ANGPTL1 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	ANGPTL1
Entrez Gene ID	9068
Full Name	angiopoietin like 1
Synonyms	ANG3,ANGPT3,ARP1,AngY,UNQ162,dJ595C2.2
General protein information	Preferred Names angiopoietin like 1 Names angiopoietin-related protein 1 ANG-3 angioarrestin angiopoietin 3 angiopoietin Y1 angiopoietin-like protein 1 dJ595C2.2 (angiopoietin Y1)
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 1 Map Location: 1q25.2
Summary	Angiopoietins are members of the vascular endothelial growth factor family and the only known growth factors largely specific for vascular endothelium. Angiopoietin-1, angiopoietin-2, and angiopoietin-4 participate in the formation of blood vessels. The protein encoded by this gene is another member of the angiopoietin family that is widely expressed in adult tissues with mRNA levels highest in highly vascularized tissues. This protein was found to be a secretory protein that does not act as an endothelial cell mitogen in vitro. [provided by RefSeq, Jul 2008].
Disorder MIM:	603874

mRNA and Protein(s)

mRNA	Protein	Name
NM_004673.3	NP_004664.1	angiopoietin-related protein 1 precursor
XM_005245577.2	XP_005245634.1	angiopoietin-related protein 1 isoform X1
NM_001376763.1	NP_001363692.1	angiopoietin-related protein 1 precursor
XM_005245577.3	XP_005245634.1	angiopoietin-related protein 1 isoform X1
NM_004673.4	NP_004664.1	angiopoietin-related protein 1 precursor

Pathways from BioSystems

Homologies

Gallus gallus (chicken)	ANGPTL1	NP_001264594.1
Bos taurus (cattle)	ANGPTL1	NP_001068894.1
Mus musculus (house mouse)	Angptl1	NP_082609.2
Homo sapiens (human)	ANGPTL1	NP_004664.1
Pan troglodytes (chimpanzee)	ANGPTL1	XP_001155579.1
Canis lupus familiaris (dog)	ANGPTL1	NP_001103283.1
Xenopus tropicalis (tropical clawed frog)	angptl1	NP_001123408.1
Danio rerio (zebrafish)	angptl1	NP_001014820.1

Gene Ontology
Bibliography

Related articles in PubMed

Yan Q, Jiang L, Liu M, Yu D, Zhang Y, Li Y, Fang S, Li Y, Zhu YH, Yuan YF, Guan XY
Cancer research77(21)5831-5845(2017 Nov)

ANGPTL1 attenuates colorectal cancer metastasis by up-regulating microRNA-138.
Chen H, Xiao Q, Hu Y, Chen L, Jiang K, Tang Y, Tan Y, Hu W, Wang Z, He J, Liu Y, Cai Y, Yang Q, Ding K
Journal of experimental & clinical cancer research : CR36(1)78(2017 Jun)

Aberrant expression of angiopoietin-like proteins 1 and 2 in cumulus cells is potentially associated with impaired oocyte developmental competence in polycystic ovary syndrome.
Liu Z, Liu C, Hao C, Xue Q, Huang X, Zhang N, Bao H, Qu Q
Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology32(7)557-61(2016 Jul)

Retinoic acid receptor beta and angiopoietin-like protein 1 are involved in the regulation of human androgen biosynthesis.
Udhane SS, Pandey AV, Hofer G, Mullis PE, Fl?ck CE
Scientific reports510132(2015 May)

Discovery and refinement of loci associated with lipid levels.
Willer CJ, Schmidt EM, Sengupta S, Peloso GM, Gustafsson S, Kanoni S, Ganna A, Chen J, Buchkovich ML, Mora S, Beckmann JS, Bragg-Gresham JL, Chang HY, Demirkan A, Den Hertog HM, Do R, Donnelly LA, Ehret GB, Esko T, Feitosa MF, Ferreira T, Fischer K, Fontanillas P, Fraser RM, Freitag DF, Gurdasani D, Heikkil? K, Hypp?nen E, Isaacs A, Jackson AU, Johansson ?, Johnson T, Kaakinen M, Kettunen J, Kleber ME, Li X, Luan J, Lyytik?inen LP, Magnusson PKE, Mangino M, Mihailov E, Montasser ME, M?ller-Nurasyid M, Nolte IM, O'Connell JR, Palmer CD, Perola M, Petersen AK, Sanna S, Saxena R, Service SK, Shah S, Shungin D, Sidore C, Song C, Strawbridge RJ, Surakka I, Tanaka T, Teslovich TM, Thorleifsson G, Van den Herik EG, Voight BF, Volcik KA, Waite LL, Wong A, Wu Y, Zhang W, Absher D, Asiki G, Barroso I, Been LF, Bolton JL, Bonnycastle LL, Brambilla P, Burnett MS, Cesana G, Dimitriou M, Doney ASF, D?ring A, Elliott P, Epstein SE, Ingi Eyjolfsson G, Gigante B, Goodarzi MO, Grallert H, Gravito ML, Groves CJ, Hallmans G, Hartikainen AL, Hayward C, Hernandez D, Hicks AA, Holm H, Hung YJ, Illig T, Jones MR, Kaleebu P, Kastelein JJP, Khaw KT, Kim E, Klopp N, Komulainen P, Kumari M, Langenberg C, Lehtim?ki T, Lin SY, Lindstr?m J, Loos RJF, Mach F, McArdle WL, Meisinger C, Mitchell BD, M?ller G, Nagaraja R, Narisu N, Nieminen TVM, Nsubuga RN, Olafsson I, Ong KK, Palotie A, Papamarkou T, Pomilla C, Pouta A, Rader DJ, Reilly MP, Ridker PM, Rivadeneira F, Rudan I, Ruokonen A, Samani N, Scharnagl H, Seeley J, Silander K, Stan??kov? A, Stirrups K, Swift AJ, Tiret L, Uitterlinden AG, van Pelt LJ, Vedantam S, Wainwright N, Wijmenga C, Wild SH, Willemsen G, Wilsgaard T, Wilson JF, Young EH, Zhao JH, Adair LS, Arveiler D, Assimes TL, Bandinelli S, Bennett F, Bochud M, Boehm BO, Boomsma DI, Borecki IB, Bornstein SR, Bovet P, Burnier M, Campbell H, Chakravarti A, Chambers JC, Chen YI, Collins FS, Cooper RS, Danesh J, Dedoussis G, de Faire U, Feranil AB, Ferri?res J, Ferrucci L, Freimer NB, Gieger C, Groop LC, Gudnason V, Gyllensten U, Hamsten A, Harris TB, Hingorani A, Hirschhorn JN, Hofman A, Hovingh GK, Hsiung CA, Humphries SE, Hunt SC, Hveem K, Iribarren C, J?rvelin MR, Jula A, K?h?nen M, Kaprio J, Kes?niemi A, Kivimaki M, Kooner JS, Koudstaal PJ, Krauss RM, Kuh D, Kuusisto J, Kyvik KO, Laakso M, Lakka TA, Lind L, Lindgren CM, Martin NG, M?rz W, McCarthy MI, McKenzie CA, Meneton P, Metspalu A, Moilanen L, Morris AD, Munroe PB, Nj?lstad I, Pedersen NL, Power C, Pramstaller PP, Price JF, Psaty BM, Quertermous T, Rauramaa R, Saleheen D, Salomaa V, Sanghera DK, Saramies J, Schwarz PEH, Sheu WH, Shuldiner AR, Siegbahn A, Spector TD, Stefansson K, Strachan DP, Tayo BO, Tremoli E, Tuomilehto J, Uusitupa M, van Duijn CM, Vollenweider P, Wallentin L, Wareham NJ, Whitfield JB, Wolffenbuttel BHR, Ordovas JM, Boerwinkle E, Palmer CNA, Thorsteinsdottir U, Chasman DI, Rotter JI, Franks PW, Ripatti S, Cupples LA, Sandhu MS, Rich SS, Boehnke M, Deloukas P, Kathiresan S, Mohlke KL, Ingelsson E, Abecasis GR,
Nature genetics45(11)1274-1283(2013 Nov)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

ANGPTL1 inhibited angiogenesis by interacting with integrin alpha1beta1 receptor to suppress the downstreamJAK2-STAT3 signaling pathway.

Aberrant expression of ANGPTL1 in cumulus cells is potentially associated with impaired oocyte developmental competence in polycystic ovary syndrome.
Title: Aberrant expression of angiopoietin-like proteins 1 and 2 in cumulus cells is potentially associated with impaired oocyte developmental competence in polycystic ovary syndrome.

Retinoic acid receptor beta and angiopoietin-like protein 1 are involved in the regulation of human androgen biosynthesis
Title: Retinoic acid receptor beta and angiopoietin-like protein 1 are involved in the regulation of human androgen biosynthesis.

ANGPTL1 represses lung cancer cell motility by abrogating the expression of the epithelial mesenchymal transformation mediator SLUG.
Title: Angiopoietin-like protein 1 suppresses SLUG to inhibit cancer cell motility.

Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
Title: MicroRNA-related genetic variations as predictors for risk of second primary tumor and/or recurrence in patients with early-stage head and neck cancer.

The following ANGPTL1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the ANGPTL1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu24901	NM_004673.4 Latest version!	Homo sapiens angiopoietin like 1 (ANGPTL1), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
OHu24901	NM_001376763.1 Latest version!	Homo sapiens angiopoietin like 1 (ANGPTL1), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
OHu24901	XM_005245577.3 Latest version!	Homo sapiens angiopoietin like 1 (ANGPTL1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
View Old Accession Versions >>
OHu24901	XM_005245577.2	Homo sapiens angiopoietin like 1 (ANGPTL1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
OHu24901	NM_004673.3	Homo sapiens angiopoietin like 1 (ANGPTL1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

ANGPTL1 ( NM_004673.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_004664.1 Homo sapiens angiopoietin like 1 (ANGPTL1), mRNA.

Price & Availability↑

CloneID	OHu24901
Clone ID Related Accession (Same CDS sequence)	NM_004673.3 , XM_005245577.2 , NM_001376763.1 , XM_005245577.3 , NM_004673.4
Accession Version	NM_004673.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1476bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-12-05
Organism	Homo sapiens(human)
Product	angiopoietin-related protein 1 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from CD356427.1, BX499002.1, AY358278.1, BC050640.1, BM710120.1 and AF086266.1. On Nov 14, 2003 this sequence version replaced NM_004673.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803613.47398.1, SRR1803613.71505.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968189, SAMEA2142348 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAAGACTT TTACCTGGAC CCTAGGTGTG CTATTCTTCC TACTAGTGGA CACTGGACAT 
TGCAGAGGTG GACAATTCAA AATTAAAAAA ATAAACCAGA GAAGATACCC TCGTGCCACA 
GATGGTAAAG AGGAAGCAAA GAAATGTGCA TACACATTCC TGGTACCTGA ACAAAGAATA 
ACAGGGCCAA TCTGTGTCAA CACCAAGGGG CAAGATGCAA GTACCATTAA AGACATGATC 
ACCAGGATGG ACCTTGAAAA CCTGAAGGAT GTGCTCTCCA GGCAGAAGCG GGAGATAGAT 
GTTCTGCAAC TGGTGGTGGA TGTAGATGGA AACATTGTGA ATGAGGTAAA GCTGCTGAGA 
AAGGAAAGCC GTAACATGAA CTCTCGTGTT ACTCAACTCT ATATGCAATT ATTACATGAG 
ATTATCCGTA AGAGGGATAA TTCACTTGAA CTTTCCCAAC TGGAAAACAA AATCCTCAAT 
GTCACCACAG AAATGTTGAA GATGGCAACA AGATACAGGG AACTAGAGGT GAAATACGCT 
TCCTTGACTG ATCTTGTCAA TAACCAATCT GTGATGATCA CTTTGTTGGA AGAACAGTGC 
TTGAGGATAT TTTCCCGACA AGACACCCAT GTGTCTCCCC CACTTGTCCA GGTGGTGCCA 
CAACATATTC CTAACAGCCA ACAGTATACT CCTGGTCTGC TGGGAGGTAA CGAGATTCAG 
AGGGATCCAG GTTATCCCAG AGATTTAATG CCACCACCTG ATCTGGCAAC TTCTCCCACC 
AAAAGCCCTT TCAAGATACC ACCGGTAACT TTCATCAATG AAGGACCATT CAAAGACTGT 
CAGCAAGCAA AAGAAGCTGG GCATTCGGTC AGTGGGATTT ATATGATTAA ACCTGAAAAC 
AGCAATGGAC CAATGCAGTT ATGGTGTGAA AACAGTTTGG ACCCTGGGGG TTGGACTGTT 
ATTCAGAAAA GAACAGACGG CTCTGTCAAC TTCTTCAGAA ATTGGGAAAA TTATAAGAAA 
GGGTTTGGAA ACATTGACGG AGAATACTGG CTTGGACTGG AAAATATCTA TATGCTTAGC 
AATCAAGATA ATTACAAGTT ATTGATTGAA TTAGAAGACT GGAGTGATAA AAAAGTCTAT 
GCAGAATACA GCAGCTTTCG TCTGGAACCT GAAAGTGAAT TCTATAGACT GCGCCTGGGA 
ACTTACCAGG GAAATGCAGG GGATTCTATG ATGTGGCATA ATGGTAAACA ATTCACCACA 
CTGGACAGAG ATAAAGATAT GTATGCAGGA AACTGCGCCC ACTTTCATAA AGGAGGCTGG 
TGGTACAATG CCTGTGCACA TTCTAACCTA AATGGAGTAT GGTACAGAGG AGGCCATTAC 
AGAAGCAAGC ACCAAGATGG AATTTTCTGG GCCGAATACA GAGGCGGGTC ATACTCCTTA 
AGAGCAGTTC AGATGATGAT CAAGCCTATT GACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_004664.1
CDS	477..1952
Translation	MKTFTWTLGVLFFLLVDTGHCRGGQFKIKKINQRRYPRATDGKEEAKKCAYTFLVPEQRITGPICVNTKGQDASTIKDMITRMDLENLKDVLSRQKREIDVLQLVVDVDGNIVNEVKLLRKESRNMNSRVTQLYMQLLHEIIRKRDNSLELSQLENKILNVTTEMLKMATRYRELEVKYASLTDLVNNQSVMITLLEEQCLRIFSRQDTHVSPPLVQVVPQHIPNSQQYTPGLLGGNEIQRDPGYPRDLMPPPDLATSPTKSPFKIPPVTFINEGPFKDCQQAKEAGHSVSGIYMIKPENSNGPMQLWCENSLDPGGWTVIQKRTDGSVNFFRNWENYKKGFGNIDGEYWLGLENIYMLSNQDNYKLLIELEDWSDKKVYAEYSSFRLEPESEFYRLRLGTYQGNAGDSMMWHNGKQFTTLDRDKDMYAGNCAHFHKGGWWYNACAHSNLNGVWYRGGHYRSKHQDGIFWAEYRGGSYSLRAVQMMIKPID

Target ORF information:

RefSeq Version	NM_004673.3
Organism	Homo sapiens(human)
Definition	Homo sapiens angiopoietin like 1 (ANGPTL1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_004673.3

ORF Insert Sequence:

ATGAAGACTT TTACCTGGAC CCTAGGTGTG CTATTCTTCC TACTAGTGGA CACTGGACAT 
TGCAGAGGTG GACAATTCAA AATTAAAAAA ATAAACCAGA GAAGATACCC TCGTGCCACA 
GATGGTAAAG AGGAAGCAAA GAAATGTGCA TACACATTCC TGGTACCTGA ACAAAGAATA 
ACAGGGCCAA TCTGTGTCAA CACCAAGGGG CAAGATGCAA GTACCATTAA AGACATGATC 
ACCAGGATGG ACCTTGAAAA CCTGAAGGAT GTGCTCTCCA GGCAGAAGCG GGAGATAGAT 
GTTCTGCAAC TGGTGGTGGA TGTAGATGGA AACATTGTGA ATGAGGTAAA GCTGCTGAGA 
AAGGAAAGCC GTAACATGAA CTCTCGTGTT ACTCAACTCT ATATGCAATT ATTACATGAG 
ATTATCCGTA AGAGGGATAA TTCACTTGAA CTTTCCCAAC TGGAAAACAA AATCCTCAAT 
GTCACCACAG AAATGTTGAA GATGGCAACA AGATACAGGG AACTAGAGGT GAAATACGCT 
TCCTTGACTG ATCTTGTCAA TAACCAATCT GTGATGATCA CTTTGTTGGA AGAACAGTGC 
TTGAGGATAT TTTCCCGACA AGACACCCAT GTGTCTCCCC CACTTGTCCA GGTGGTGCCA 
CAACATATTC CTAACAGCCA ACAGTATACT CCTGGTCTGC TGGGAGGTAA CGAGATTCAG 
AGGGATCCAG GTTATCCCAG AGATTTAATG CCACCACCTG ATCTGGCAAC TTCTCCCACC 
AAAAGCCCTT TCAAGATACC ACCGGTAACT TTCATCAATG AAGGACCATT CAAAGACTGT 
CAGCAAGCAA AAGAAGCTGG GCATTCGGTC AGTGGGATTT ATATGATTAA ACCTGAAAAC 
AGCAATGGAC CAATGCAGTT ATGGTGTGAA AACAGTTTGG ACCCTGGGGG TTGGACTGTT 
ATTCAGAAAA GAACAGACGG CTCTGTCAAC TTCTTCAGAA ATTGGGAAAA TTATAAGAAA 
GGGTTTGGAA ACATTGACGG AGAATACTGG CTTGGACTGG AAAATATCTA TATGCTTAGC 
AATCAAGATA ATTACAAGTT ATTGATTGAA TTAGAAGACT GGAGTGATAA AAAAGTCTAT 
GCAGAATACA GCAGCTTTCG TCTGGAACCT GAAAGTGAAT TCTATAGACT GCGCCTGGGA 
ACTTACCAGG GAAATGCAGG GGATTCTATG ATGTGGCATA ATGGTAAACA ATTCACCACA 
CTGGACAGAG ATAAAGATAT GTATGCAGGA AACTGCGCCC ACTTTCATAA AGGAGGCTGG 
TGGTACAATG CCTGTGCACA TTCTAACCTA AATGGAGTAT GGTACAGAGG AGGCCATTAC 
AGAAGCAAGC ACCAAGATGG AATTTTCTGG GCCGAATACA GAGGCGGGTC ATACTCCTTA 
AGAGCAGTTC AGATGATGAT CAAGCCTATT GACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ANGPTL1 ( NM_001376763.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001363692.1 Homo sapiens angiopoietin like 1 (ANGPTL1), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu24901
Clone ID Related Accession (Same CDS sequence)	NM_004673.3 , XM_005245577.2 , NM_001376763.1 , XM_005245577.3 , NM_004673.4
Accession Version	NM_001376763.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1476bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2020-01-04
Organism	Homo sapiens(human)
Product	angiopoietin-related protein 1 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AL355520.8. On Nov 20, 2019 this sequence version replaced XM_005245577.3. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC050640.1, SRR1803611.88421.1 [ECO:0000332] ##Evidence-Data-END##

ATGAAGACTT TTACCTGGAC CCTAGGTGTG CTATTCTTCC TACTAGTGGA CACTGGACAT 
TGCAGAGGTG GACAATTCAA AATTAAAAAA ATAAACCAGA GAAGATACCC TCGTGCCACA 
GATGGTAAAG AGGAAGCAAA GAAATGTGCA TACACATTCC TGGTACCTGA ACAAAGAATA 
ACAGGGCCAA TCTGTGTCAA CACCAAGGGG CAAGATGCAA GTACCATTAA AGACATGATC 
ACCAGGATGG ACCTTGAAAA CCTGAAGGAT GTGCTCTCCA GGCAGAAGCG GGAGATAGAT 
GTTCTGCAAC TGGTGGTGGA TGTAGATGGA AACATTGTGA ATGAGGTAAA GCTGCTGAGA 
AAGGAAAGCC GTAACATGAA CTCTCGTGTT ACTCAACTCT ATATGCAATT ATTACATGAG 
ATTATCCGTA AGAGGGATAA TTCACTTGAA CTTTCCCAAC TGGAAAACAA AATCCTCAAT 
GTCACCACAG AAATGTTGAA GATGGCAACA AGATACAGGG AACTAGAGGT GAAATACGCT 
TCCTTGACTG ATCTTGTCAA TAACCAATCT GTGATGATCA CTTTGTTGGA AGAACAGTGC 
TTGAGGATAT TTTCCCGACA AGACACCCAT GTGTCTCCCC CACTTGTCCA GGTGGTGCCA 
CAACATATTC CTAACAGCCA ACAGTATACT CCTGGTCTGC TGGGAGGTAA CGAGATTCAG 
AGGGATCCAG GTTATCCCAG AGATTTAATG CCACCACCTG ATCTGGCAAC TTCTCCCACC 
AAAAGCCCTT TCAAGATACC ACCGGTAACT TTCATCAATG AAGGACCATT CAAAGACTGT 
CAGCAAGCAA AAGAAGCTGG GCATTCGGTC AGTGGGATTT ATATGATTAA ACCTGAAAAC 
AGCAATGGAC CAATGCAGTT ATGGTGTGAA AACAGTTTGG ACCCTGGGGG TTGGACTGTT 
ATTCAGAAAA GAACAGACGG CTCTGTCAAC TTCTTCAGAA ATTGGGAAAA TTATAAGAAA 
GGGTTTGGAA ACATTGACGG AGAATACTGG CTTGGACTGG AAAATATCTA TATGCTTAGC 
AATCAAGATA ATTACAAGTT ATTGATTGAA TTAGAAGACT GGAGTGATAA AAAAGTCTAT 
GCAGAATACA GCAGCTTTCG TCTGGAACCT GAAAGTGAAT TCTATAGACT GCGCCTGGGA 
ACTTACCAGG GAAATGCAGG GGATTCTATG ATGTGGCATA ATGGTAAACA ATTCACCACA 
CTGGACAGAG ATAAAGATAT GTATGCAGGA AACTGCGCCC ACTTTCATAA AGGAGGCTGG 
TGGTACAATG CCTGTGCACA TTCTAACCTA AATGGAGTAT GGTACAGAGG AGGCCATTAC 
AGAAGCAAGC ACCAAGATGG AATTTTCTGG GCCGAATACA GAGGCGGGTC ATACTCCTTA 
AGAGCAGTTC AGATGATGAT CAAGCCTATT GACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001363692.1
CDS	364..1839
Translation	MKTFTWTLGVLFFLLVDTGHCRGGQFKIKKINQRRYPRATDGKEEAKKCAYTFLVPEQRITGPICVNTKGQDASTIKDMITRMDLENLKDVLSRQKREIDVLQLVVDVDGNIVNEVKLLRKESRNMNSRVTQLYMQLLHEIIRKRDNSLELSQLENKILNVTTEMLKMATRYRELEVKYASLTDLVNNQSVMITLLEEQCLRIFSRQDTHVSPPLVQVVPQHIPNSQQYTPGLLGGNEIQRDPGYPRDLMPPPDLATSPTKSPFKIPPVTFINEGPFKDCQQAKEAGHSVSGIYMIKPENSNGPMQLWCENSLDPGGWTVIQKRTDGSVNFFRNWENYKKGFGNIDGEYWLGLENIYMLSNQDNYKLLIELEDWSDKKVYAEYSSFRLEPESEFYRLRLGTYQGNAGDSMMWHNGKQFTTLDRDKDMYAGNCAHFHKGGWWYNACAHSNLNGVWYRGGHYRSKHQDGIFWAEYRGGSYSLRAVQMMIKPID

Target ORF information:

RefSeq Version	NM_001376763.1
Organism	Homo sapiens(human)
Definition	Homo sapiens angiopoietin like 1 (ANGPTL1), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001376763.1

ORF Insert Sequence:

ATGAAGACTT TTACCTGGAC CCTAGGTGTG CTATTCTTCC TACTAGTGGA CACTGGACAT 
TGCAGAGGTG GACAATTCAA AATTAAAAAA ATAAACCAGA GAAGATACCC TCGTGCCACA 
GATGGTAAAG AGGAAGCAAA GAAATGTGCA TACACATTCC TGGTACCTGA ACAAAGAATA 
ACAGGGCCAA TCTGTGTCAA CACCAAGGGG CAAGATGCAA GTACCATTAA AGACATGATC 
ACCAGGATGG ACCTTGAAAA CCTGAAGGAT GTGCTCTCCA GGCAGAAGCG GGAGATAGAT 
GTTCTGCAAC TGGTGGTGGA TGTAGATGGA AACATTGTGA ATGAGGTAAA GCTGCTGAGA 
AAGGAAAGCC GTAACATGAA CTCTCGTGTT ACTCAACTCT ATATGCAATT ATTACATGAG 
ATTATCCGTA AGAGGGATAA TTCACTTGAA CTTTCCCAAC TGGAAAACAA AATCCTCAAT 
GTCACCACAG AAATGTTGAA GATGGCAACA AGATACAGGG AACTAGAGGT GAAATACGCT 
TCCTTGACTG ATCTTGTCAA TAACCAATCT GTGATGATCA CTTTGTTGGA AGAACAGTGC 
TTGAGGATAT TTTCCCGACA AGACACCCAT GTGTCTCCCC CACTTGTCCA GGTGGTGCCA 
CAACATATTC CTAACAGCCA ACAGTATACT CCTGGTCTGC TGGGAGGTAA CGAGATTCAG 
AGGGATCCAG GTTATCCCAG AGATTTAATG CCACCACCTG ATCTGGCAAC TTCTCCCACC 
AAAAGCCCTT TCAAGATACC ACCGGTAACT TTCATCAATG AAGGACCATT CAAAGACTGT 
CAGCAAGCAA AAGAAGCTGG GCATTCGGTC AGTGGGATTT ATATGATTAA ACCTGAAAAC 
AGCAATGGAC CAATGCAGTT ATGGTGTGAA AACAGTTTGG ACCCTGGGGG TTGGACTGTT 
ATTCAGAAAA GAACAGACGG CTCTGTCAAC TTCTTCAGAA ATTGGGAAAA TTATAAGAAA 
GGGTTTGGAA ACATTGACGG AGAATACTGG CTTGGACTGG AAAATATCTA TATGCTTAGC 
AATCAAGATA ATTACAAGTT ATTGATTGAA TTAGAAGACT GGAGTGATAA AAAAGTCTAT 
GCAGAATACA GCAGCTTTCG TCTGGAACCT GAAAGTGAAT TCTATAGACT GCGCCTGGGA 
ACTTACCAGG GAAATGCAGG GGATTCTATG ATGTGGCATA ATGGTAAACA ATTCACCACA 
CTGGACAGAG ATAAAGATAT GTATGCAGGA AACTGCGCCC ACTTTCATAA AGGAGGCTGG 
TGGTACAATG CCTGTGCACA TTCTAACCTA AATGGAGTAT GGTACAGAGG AGGCCATTAC 
AGAAGCAAGC ACCAAGATGG AATTTTCTGG GCCGAATACA GAGGCGGGTC ATACTCCTTA 
AGAGCAGTTC AGATGATGAT CAAGCCTATT GACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ANGPTL1 ( NM_004673.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_004664.1 Homo sapiens angiopoietin like 1 (ANGPTL1), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu24901
Clone ID Related Accession (Same CDS sequence)	NM_004673.3 , XM_005245577.2 , NM_001376763.1 , XM_005245577.3 , NM_004673.4
Accession Version	NM_004673.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1476bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-30
Organism	Homo sapiens(human)
Product	angiopoietin-related protein 1 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BX499002.1, AY358278.1, BC050640.1, BM710120.1 and AF086266.1. On Nov 22, 2018 this sequence version replaced NM_004673.3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803613.47398.1, AY358278.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968189, SAMEA2142348 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000234816.7/ ENSP00000234816.2 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGAAGACTT TTACCTGGAC CCTAGGTGTG CTATTCTTCC TACTAGTGGA CACTGGACAT 
TGCAGAGGTG GACAATTCAA AATTAAAAAA ATAAACCAGA GAAGATACCC TCGTGCCACA 
GATGGTAAAG AGGAAGCAAA GAAATGTGCA TACACATTCC TGGTACCTGA ACAAAGAATA 
ACAGGGCCAA TCTGTGTCAA CACCAAGGGG CAAGATGCAA GTACCATTAA AGACATGATC 
ACCAGGATGG ACCTTGAAAA CCTGAAGGAT GTGCTCTCCA GGCAGAAGCG GGAGATAGAT 
GTTCTGCAAC TGGTGGTGGA TGTAGATGGA AACATTGTGA ATGAGGTAAA GCTGCTGAGA 
AAGGAAAGCC GTAACATGAA CTCTCGTGTT ACTCAACTCT ATATGCAATT ATTACATGAG 
ATTATCCGTA AGAGGGATAA TTCACTTGAA CTTTCCCAAC TGGAAAACAA AATCCTCAAT 
GTCACCACAG AAATGTTGAA GATGGCAACA AGATACAGGG AACTAGAGGT GAAATACGCT 
TCCTTGACTG ATCTTGTCAA TAACCAATCT GTGATGATCA CTTTGTTGGA AGAACAGTGC 
TTGAGGATAT TTTCCCGACA AGACACCCAT GTGTCTCCCC CACTTGTCCA GGTGGTGCCA 
CAACATATTC CTAACAGCCA ACAGTATACT CCTGGTCTGC TGGGAGGTAA CGAGATTCAG 
AGGGATCCAG GTTATCCCAG AGATTTAATG CCACCACCTG ATCTGGCAAC TTCTCCCACC 
AAAAGCCCTT TCAAGATACC ACCGGTAACT TTCATCAATG AAGGACCATT CAAAGACTGT 
CAGCAAGCAA AAGAAGCTGG GCATTCGGTC AGTGGGATTT ATATGATTAA ACCTGAAAAC 
AGCAATGGAC CAATGCAGTT ATGGTGTGAA AACAGTTTGG ACCCTGGGGG TTGGACTGTT 
ATTCAGAAAA GAACAGACGG CTCTGTCAAC TTCTTCAGAA ATTGGGAAAA TTATAAGAAA 
GGGTTTGGAA ACATTGACGG AGAATACTGG CTTGGACTGG AAAATATCTA TATGCTTAGC 
AATCAAGATA ATTACAAGTT ATTGATTGAA TTAGAAGACT GGAGTGATAA AAAAGTCTAT 
GCAGAATACA GCAGCTTTCG TCTGGAACCT GAAAGTGAAT TCTATAGACT GCGCCTGGGA 
ACTTACCAGG GAAATGCAGG GGATTCTATG ATGTGGCATA ATGGTAAACA ATTCACCACA 
CTGGACAGAG ATAAAGATAT GTATGCAGGA AACTGCGCCC ACTTTCATAA AGGAGGCTGG 
TGGTACAATG CCTGTGCACA TTCTAACCTA AATGGAGTAT GGTACAGAGG AGGCCATTAC 
AGAAGCAAGC ACCAAGATGG AATTTTCTGG GCCGAATACA GAGGCGGGTC ATACTCCTTA 
AGAGCAGTTC AGATGATGAT CAAGCCTATT GACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_004664.1
CDS	474..1949
Translation	MKTFTWTLGVLFFLLVDTGHCRGGQFKIKKINQRRYPRATDGKEEAKKCAYTFLVPEQRITGPICVNTKGQDASTIKDMITRMDLENLKDVLSRQKREIDVLQLVVDVDGNIVNEVKLLRKESRNMNSRVTQLYMQLLHEIIRKRDNSLELSQLENKILNVTTEMLKMATRYRELEVKYASLTDLVNNQSVMITLLEEQCLRIFSRQDTHVSPPLVQVVPQHIPNSQQYTPGLLGGNEIQRDPGYPRDLMPPPDLATSPTKSPFKIPPVTFINEGPFKDCQQAKEAGHSVSGIYMIKPENSNGPMQLWCENSLDPGGWTVIQKRTDGSVNFFRNWENYKKGFGNIDGEYWLGLENIYMLSNQDNYKLLIELEDWSDKKVYAEYSSFRLEPESEFYRLRLGTYQGNAGDSMMWHNGKQFTTLDRDKDMYAGNCAHFHKGGWWYNACAHSNLNGVWYRGGHYRSKHQDGIFWAEYRGGSYSLRAVQMMIKPID

Target ORF information:

RefSeq Version	NM_004673.4
Organism	Homo sapiens(human)
Definition	Homo sapiens angiopoietin like 1 (ANGPTL1), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_004673.4

ORF Insert Sequence:

ATGAAGACTT TTACCTGGAC CCTAGGTGTG CTATTCTTCC TACTAGTGGA CACTGGACAT 
TGCAGAGGTG GACAATTCAA AATTAAAAAA ATAAACCAGA GAAGATACCC TCGTGCCACA 
GATGGTAAAG AGGAAGCAAA GAAATGTGCA TACACATTCC TGGTACCTGA ACAAAGAATA 
ACAGGGCCAA TCTGTGTCAA CACCAAGGGG CAAGATGCAA GTACCATTAA AGACATGATC 
ACCAGGATGG ACCTTGAAAA CCTGAAGGAT GTGCTCTCCA GGCAGAAGCG GGAGATAGAT 
GTTCTGCAAC TGGTGGTGGA TGTAGATGGA AACATTGTGA ATGAGGTAAA GCTGCTGAGA 
AAGGAAAGCC GTAACATGAA CTCTCGTGTT ACTCAACTCT ATATGCAATT ATTACATGAG 
ATTATCCGTA AGAGGGATAA TTCACTTGAA CTTTCCCAAC TGGAAAACAA AATCCTCAAT 
GTCACCACAG AAATGTTGAA GATGGCAACA AGATACAGGG AACTAGAGGT GAAATACGCT 
TCCTTGACTG ATCTTGTCAA TAACCAATCT GTGATGATCA CTTTGTTGGA AGAACAGTGC 
TTGAGGATAT TTTCCCGACA AGACACCCAT GTGTCTCCCC CACTTGTCCA GGTGGTGCCA 
CAACATATTC CTAACAGCCA ACAGTATACT CCTGGTCTGC TGGGAGGTAA CGAGATTCAG 
AGGGATCCAG GTTATCCCAG AGATTTAATG CCACCACCTG ATCTGGCAAC TTCTCCCACC 
AAAAGCCCTT TCAAGATACC ACCGGTAACT TTCATCAATG AAGGACCATT CAAAGACTGT 
CAGCAAGCAA AAGAAGCTGG GCATTCGGTC AGTGGGATTT ATATGATTAA ACCTGAAAAC 
AGCAATGGAC CAATGCAGTT ATGGTGTGAA AACAGTTTGG ACCCTGGGGG TTGGACTGTT 
ATTCAGAAAA GAACAGACGG CTCTGTCAAC TTCTTCAGAA ATTGGGAAAA TTATAAGAAA 
GGGTTTGGAA ACATTGACGG AGAATACTGG CTTGGACTGG AAAATATCTA TATGCTTAGC 
AATCAAGATA ATTACAAGTT ATTGATTGAA TTAGAAGACT GGAGTGATAA AAAAGTCTAT 
GCAGAATACA GCAGCTTTCG TCTGGAACCT GAAAGTGAAT TCTATAGACT GCGCCTGGGA 
ACTTACCAGG GAAATGCAGG GGATTCTATG ATGTGGCATA ATGGTAAACA ATTCACCACA 
CTGGACAGAG ATAAAGATAT GTATGCAGGA AACTGCGCCC ACTTTCATAA AGGAGGCTGG 
TGGTACAATG CCTGTGCACA TTCTAACCTA AATGGAGTAT GGTACAGAGG AGGCCATTAC 
AGAAGCAAGC ACCAAGATGG AATTTTCTGG GCCGAATACA GAGGCGGGTC ATACTCCTTA 
AGAGCAGTTC AGATGATGAT CAAGCCTATT GACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ANGPTL1 ( XM_005245577.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_005245634.1 Homo sapiens angiopoietin like 1 (ANGPTL1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu24901
Clone ID Related Accession (Same CDS sequence)	NM_004673.3 , XM_005245577.2 , NM_001376763.1 , XM_005245577.3 , NM_004673.4
Accession Version	XM_005245577.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1476bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	angiopoietin-related protein 1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000001.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 12, 2015 this sequence version replaced XM_005245577.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAAGACTT TTACCTGGAC CCTAGGTGTG CTATTCTTCC TACTAGTGGA CACTGGACAT 
TGCAGAGGTG GACAATTCAA AATTAAAAAA ATAAACCAGA GAAGATACCC TCGTGCCACA 
GATGGTAAAG AGGAAGCAAA GAAATGTGCA TACACATTCC TGGTACCTGA ACAAAGAATA 
ACAGGGCCAA TCTGTGTCAA CACCAAGGGG CAAGATGCAA GTACCATTAA AGACATGATC 
ACCAGGATGG ACCTTGAAAA CCTGAAGGAT GTGCTCTCCA GGCAGAAGCG GGAGATAGAT 
GTTCTGCAAC TGGTGGTGGA TGTAGATGGA AACATTGTGA ATGAGGTAAA GCTGCTGAGA 
AAGGAAAGCC GTAACATGAA CTCTCGTGTT ACTCAACTCT ATATGCAATT ATTACATGAG 
ATTATCCGTA AGAGGGATAA TTCACTTGAA CTTTCCCAAC TGGAAAACAA AATCCTCAAT 
GTCACCACAG AAATGTTGAA GATGGCAACA AGATACAGGG AACTAGAGGT GAAATACGCT 
TCCTTGACTG ATCTTGTCAA TAACCAATCT GTGATGATCA CTTTGTTGGA AGAACAGTGC 
TTGAGGATAT TTTCCCGACA AGACACCCAT GTGTCTCCCC CACTTGTCCA GGTGGTGCCA 
CAACATATTC CTAACAGCCA ACAGTATACT CCTGGTCTGC TGGGAGGTAA CGAGATTCAG 
AGGGATCCAG GTTATCCCAG AGATTTAATG CCACCACCTG ATCTGGCAAC TTCTCCCACC 
AAAAGCCCTT TCAAGATACC ACCGGTAACT TTCATCAATG AAGGACCATT CAAAGACTGT 
CAGCAAGCAA AAGAAGCTGG GCATTCGGTC AGTGGGATTT ATATGATTAA ACCTGAAAAC 
AGCAATGGAC CAATGCAGTT ATGGTGTGAA AACAGTTTGG ACCCTGGGGG TTGGACTGTT 
ATTCAGAAAA GAACAGACGG CTCTGTCAAC TTCTTCAGAA ATTGGGAAAA TTATAAGAAA 
GGGTTTGGAA ACATTGACGG AGAATACTGG CTTGGACTGG AAAATATCTA TATGCTTAGC 
AATCAAGATA ATTACAAGTT ATTGATTGAA TTAGAAGACT GGAGTGATAA AAAAGTCTAT 
GCAGAATACA GCAGCTTTCG TCTGGAACCT GAAAGTGAAT TCTATAGACT GCGCCTGGGA 
ACTTACCAGG GAAATGCAGG GGATTCTATG ATGTGGCATA ATGGTAAACA ATTCACCACA 
CTGGACAGAG ATAAAGATAT GTATGCAGGA AACTGCGCCC ACTTTCATAA AGGAGGCTGG 
TGGTACAATG CCTGTGCACA TTCTAACCTA AATGGAGTAT GGTACAGAGG AGGCCATTAC 
AGAAGCAAGC ACCAAGATGG AATTTTCTGG GCCGAATACA GAGGCGGGTC ATACTCCTTA 
AGAGCAGTTC AGATGATGAT CAAGCCTATT GACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005245634.1
CDS	640..2115
Translation	MKTFTWTLGVLFFLLVDTGHCRGGQFKIKKINQRRYPRATDGKEEAKKCAYTFLVPEQRITGPICVNTKGQDASTIKDMITRMDLENLKDVLSRQKREIDVLQLVVDVDGNIVNEVKLLRKESRNMNSRVTQLYMQLLHEIIRKRDNSLELSQLENKILNVTTEMLKMATRYRELEVKYASLTDLVNNQSVMITLLEEQCLRIFSRQDTHVSPPLVQVVPQHIPNSQQYTPGLLGGNEIQRDPGYPRDLMPPPDLATSPTKSPFKIPPVTFINEGPFKDCQQAKEAGHSVSGIYMIKPENSNGPMQLWCENSLDPGGWTVIQKRTDGSVNFFRNWENYKKGFGNIDGEYWLGLENIYMLSNQDNYKLLIELEDWSDKKVYAEYSSFRLEPESEFYRLRLGTYQGNAGDSMMWHNGKQFTTLDRDKDMYAGNCAHFHKGGWWYNACAHSNLNGVWYRGGHYRSKHQDGIFWAEYRGGSYSLRAVQMMIKPID

Target ORF information:

RefSeq Version	XM_005245577.2
Organism	Homo sapiens(human)
Definition	Homo sapiens angiopoietin like 1 (ANGPTL1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005245577.2

ORF Insert Sequence:

ATGAAGACTT TTACCTGGAC CCTAGGTGTG CTATTCTTCC TACTAGTGGA CACTGGACAT 
TGCAGAGGTG GACAATTCAA AATTAAAAAA ATAAACCAGA GAAGATACCC TCGTGCCACA 
GATGGTAAAG AGGAAGCAAA GAAATGTGCA TACACATTCC TGGTACCTGA ACAAAGAATA 
ACAGGGCCAA TCTGTGTCAA CACCAAGGGG CAAGATGCAA GTACCATTAA AGACATGATC 
ACCAGGATGG ACCTTGAAAA CCTGAAGGAT GTGCTCTCCA GGCAGAAGCG GGAGATAGAT 
GTTCTGCAAC TGGTGGTGGA TGTAGATGGA AACATTGTGA ATGAGGTAAA GCTGCTGAGA 
AAGGAAAGCC GTAACATGAA CTCTCGTGTT ACTCAACTCT ATATGCAATT ATTACATGAG 
ATTATCCGTA AGAGGGATAA TTCACTTGAA CTTTCCCAAC TGGAAAACAA AATCCTCAAT 
GTCACCACAG AAATGTTGAA GATGGCAACA AGATACAGGG AACTAGAGGT GAAATACGCT 
TCCTTGACTG ATCTTGTCAA TAACCAATCT GTGATGATCA CTTTGTTGGA AGAACAGTGC 
TTGAGGATAT TTTCCCGACA AGACACCCAT GTGTCTCCCC CACTTGTCCA GGTGGTGCCA 
CAACATATTC CTAACAGCCA ACAGTATACT CCTGGTCTGC TGGGAGGTAA CGAGATTCAG 
AGGGATCCAG GTTATCCCAG AGATTTAATG CCACCACCTG ATCTGGCAAC TTCTCCCACC 
AAAAGCCCTT TCAAGATACC ACCGGTAACT TTCATCAATG AAGGACCATT CAAAGACTGT 
CAGCAAGCAA AAGAAGCTGG GCATTCGGTC AGTGGGATTT ATATGATTAA ACCTGAAAAC 
AGCAATGGAC CAATGCAGTT ATGGTGTGAA AACAGTTTGG ACCCTGGGGG TTGGACTGTT 
ATTCAGAAAA GAACAGACGG CTCTGTCAAC TTCTTCAGAA ATTGGGAAAA TTATAAGAAA 
GGGTTTGGAA ACATTGACGG AGAATACTGG CTTGGACTGG AAAATATCTA TATGCTTAGC 
AATCAAGATA ATTACAAGTT ATTGATTGAA TTAGAAGACT GGAGTGATAA AAAAGTCTAT 
GCAGAATACA GCAGCTTTCG TCTGGAACCT GAAAGTGAAT TCTATAGACT GCGCCTGGGA 
ACTTACCAGG GAAATGCAGG GGATTCTATG ATGTGGCATA ATGGTAAACA ATTCACCACA 
CTGGACAGAG ATAAAGATAT GTATGCAGGA AACTGCGCCC ACTTTCATAA AGGAGGCTGG 
TGGTACAATG CCTGTGCACA TTCTAACCTA AATGGAGTAT GGTACAGAGG AGGCCATTAC 
AGAAGCAAGC ACCAAGATGG AATTTTCTGG GCCGAATACA GAGGCGGGTC ATACTCCTTA 
AGAGCAGTTC AGATGATGAT CAAGCCTATT GACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ANGPTL1 ( XM_005245577.3 ) cDNA ORF clone, Homo sapiens(human) -> XP_005245634.1 Homo sapiens angiopoietin like 1 (ANGPTL1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu24901
Clone ID Related Accession (Same CDS sequence)	NM_004673.3 , XM_005245577.2 , NM_001376763.1 , XM_005245577.3 , NM_004673.4
Accession Version	XM_005245577.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1476bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-06-12
Organism	Homo sapiens(human)
Product	angiopoietin-related protein 1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000001.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_005245577.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20190607 Annotation Version :: 109.20190607 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Freeze :: 20190607 ##Genome-Annotation-Data-END##

ATGAAGACTT TTACCTGGAC CCTAGGTGTG CTATTCTTCC TACTAGTGGA CACTGGACAT 
TGCAGAGGTG GACAATTCAA AATTAAAAAA ATAAACCAGA GAAGATACCC TCGTGCCACA 
GATGGTAAAG AGGAAGCAAA GAAATGTGCA TACACATTCC TGGTACCTGA ACAAAGAATA 
ACAGGGCCAA TCTGTGTCAA CACCAAGGGG CAAGATGCAA GTACCATTAA AGACATGATC 
ACCAGGATGG ACCTTGAAAA CCTGAAGGAT GTGCTCTCCA GGCAGAAGCG GGAGATAGAT 
GTTCTGCAAC TGGTGGTGGA TGTAGATGGA AACATTGTGA ATGAGGTAAA GCTGCTGAGA 
AAGGAAAGCC GTAACATGAA CTCTCGTGTT ACTCAACTCT ATATGCAATT ATTACATGAG 
ATTATCCGTA AGAGGGATAA TTCACTTGAA CTTTCCCAAC TGGAAAACAA AATCCTCAAT 
GTCACCACAG AAATGTTGAA GATGGCAACA AGATACAGGG AACTAGAGGT GAAATACGCT 
TCCTTGACTG ATCTTGTCAA TAACCAATCT GTGATGATCA CTTTGTTGGA AGAACAGTGC 
TTGAGGATAT TTTCCCGACA AGACACCCAT GTGTCTCCCC CACTTGTCCA GGTGGTGCCA 
CAACATATTC CTAACAGCCA ACAGTATACT CCTGGTCTGC TGGGAGGTAA CGAGATTCAG 
AGGGATCCAG GTTATCCCAG AGATTTAATG CCACCACCTG ATCTGGCAAC TTCTCCCACC 
AAAAGCCCTT TCAAGATACC ACCGGTAACT TTCATCAATG AAGGACCATT CAAAGACTGT 
CAGCAAGCAA AAGAAGCTGG GCATTCGGTC AGTGGGATTT ATATGATTAA ACCTGAAAAC 
AGCAATGGAC CAATGCAGTT ATGGTGTGAA AACAGTTTGG ACCCTGGGGG TTGGACTGTT 
ATTCAGAAAA GAACAGACGG CTCTGTCAAC TTCTTCAGAA ATTGGGAAAA TTATAAGAAA 
GGGTTTGGAA ACATTGACGG AGAATACTGG CTTGGACTGG AAAATATCTA TATGCTTAGC 
AATCAAGATA ATTACAAGTT ATTGATTGAA TTAGAAGACT GGAGTGATAA AAAAGTCTAT 
GCAGAATACA GCAGCTTTCG TCTGGAACCT GAAAGTGAAT TCTATAGACT GCGCCTGGGA 
ACTTACCAGG GAAATGCAGG GGATTCTATG ATGTGGCATA ATGGTAAACA ATTCACCACA 
CTGGACAGAG ATAAAGATAT GTATGCAGGA AACTGCGCCC ACTTTCATAA AGGAGGCTGG 
TGGTACAATG CCTGTGCACA TTCTAACCTA AATGGAGTAT GGTACAGAGG AGGCCATTAC 
AGAAGCAAGC ACCAAGATGG AATTTTCTGG GCCGAATACA GAGGCGGGTC ATACTCCTTA 
AGAGCAGTTC AGATGATGAT CAAGCCTATT GACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005245634.1
CDS	364..1839
Translation	MKTFTWTLGVLFFLLVDTGHCRGGQFKIKKINQRRYPRATDGKEEAKKCAYTFLVPEQRITGPICVNTKGQDASTIKDMITRMDLENLKDVLSRQKREIDVLQLVVDVDGNIVNEVKLLRKESRNMNSRVTQLYMQLLHEIIRKRDNSLELSQLENKILNVTTEMLKMATRYRELEVKYASLTDLVNNQSVMITLLEEQCLRIFSRQDTHVSPPLVQVVPQHIPNSQQYTPGLLGGNEIQRDPGYPRDLMPPPDLATSPTKSPFKIPPVTFINEGPFKDCQQAKEAGHSVSGIYMIKPENSNGPMQLWCENSLDPGGWTVIQKRTDGSVNFFRNWENYKKGFGNIDGEYWLGLENIYMLSNQDNYKLLIELEDWSDKKVYAEYSSFRLEPESEFYRLRLGTYQGNAGDSMMWHNGKQFTTLDRDKDMYAGNCAHFHKGGWWYNACAHSNLNGVWYRGGHYRSKHQDGIFWAEYRGGSYSLRAVQMMIKPID

Target ORF information:

RefSeq Version	XM_005245577.3
Organism	Homo sapiens(human)
Definition	Homo sapiens angiopoietin like 1 (ANGPTL1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005245577.3

ORF Insert Sequence:

ATGAAGACTT TTACCTGGAC CCTAGGTGTG CTATTCTTCC TACTAGTGGA CACTGGACAT 
TGCAGAGGTG GACAATTCAA AATTAAAAAA ATAAACCAGA GAAGATACCC TCGTGCCACA 
GATGGTAAAG AGGAAGCAAA GAAATGTGCA TACACATTCC TGGTACCTGA ACAAAGAATA 
ACAGGGCCAA TCTGTGTCAA CACCAAGGGG CAAGATGCAA GTACCATTAA AGACATGATC 
ACCAGGATGG ACCTTGAAAA CCTGAAGGAT GTGCTCTCCA GGCAGAAGCG GGAGATAGAT 
GTTCTGCAAC TGGTGGTGGA TGTAGATGGA AACATTGTGA ATGAGGTAAA GCTGCTGAGA 
AAGGAAAGCC GTAACATGAA CTCTCGTGTT ACTCAACTCT ATATGCAATT ATTACATGAG 
ATTATCCGTA AGAGGGATAA TTCACTTGAA CTTTCCCAAC TGGAAAACAA AATCCTCAAT 
GTCACCACAG AAATGTTGAA GATGGCAACA AGATACAGGG AACTAGAGGT GAAATACGCT 
TCCTTGACTG ATCTTGTCAA TAACCAATCT GTGATGATCA CTTTGTTGGA AGAACAGTGC 
TTGAGGATAT TTTCCCGACA AGACACCCAT GTGTCTCCCC CACTTGTCCA GGTGGTGCCA 
CAACATATTC CTAACAGCCA ACAGTATACT CCTGGTCTGC TGGGAGGTAA CGAGATTCAG 
AGGGATCCAG GTTATCCCAG AGATTTAATG CCACCACCTG ATCTGGCAAC TTCTCCCACC 
AAAAGCCCTT TCAAGATACC ACCGGTAACT TTCATCAATG AAGGACCATT CAAAGACTGT 
CAGCAAGCAA AAGAAGCTGG GCATTCGGTC AGTGGGATTT ATATGATTAA ACCTGAAAAC 
AGCAATGGAC CAATGCAGTT ATGGTGTGAA AACAGTTTGG ACCCTGGGGG TTGGACTGTT 
ATTCAGAAAA GAACAGACGG CTCTGTCAAC TTCTTCAGAA ATTGGGAAAA TTATAAGAAA 
GGGTTTGGAA ACATTGACGG AGAATACTGG CTTGGACTGG AAAATATCTA TATGCTTAGC 
AATCAAGATA ATTACAAGTT ATTGATTGAA TTAGAAGACT GGAGTGATAA AAAAGTCTAT 
GCAGAATACA GCAGCTTTCG TCTGGAACCT GAAAGTGAAT TCTATAGACT GCGCCTGGGA 
ACTTACCAGG GAAATGCAGG GGATTCTATG ATGTGGCATA ATGGTAAACA ATTCACCACA 
CTGGACAGAG ATAAAGATAT GTATGCAGGA AACTGCGCCC ACTTTCATAA AGGAGGCTGG 
TGGTACAATG CCTGTGCACA TTCTAACCTA AATGGAGTAT GGTACAGAGG AGGCCATTAC 
AGAAGCAAGC ACCAAGATGG AATTTTCTGG GCCGAATACA GAGGCGGGTC ATACTCCTTA 
AGAGCAGTTC AGATGATGAT CAAGCCTATT GACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Cancer research77(21)5831-5845(2017 Nov)
Yan Q,Jiang L,Liu M,Yu D,Zhang Y,Li Y,Fang S,Li Y,Zhu YH,Yuan YF,Guan XY

ANGPTL1 attenuates colorectal cancer metastasis by up-regulating microRNA-138.
Journal of experimental & clinical cancer research : CR36(1)78(2017 Jun)
Chen H,Xiao Q,Hu Y,Chen L,Jiang K,Tang Y,Tan Y,Hu W,Wang Z,He J,Liu Y,Cai Y,Yang Q,Ding K

Aberrant expression of angiopoietin-like proteins 1 and 2 in cumulus cells is potentially associated with impaired oocyte developmental competence in polycystic ovary syndrome.
Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology32(7)557-61(2016 Jul)
Liu Z,Liu C,Hao C,Xue Q,Huang X,Zhang N,Bao H,Qu Q

Retinoic acid receptor beta and angiopoietin-like protein 1 are involved in the regulation of human androgen biosynthesis.
Scientific reports510132(2015 May)
Udhane SS,Pandey AV,Hofer G,Mullis PE,Fl?ck CE

Discovery and refinement of loci associated with lipid levels.
Nature genetics45(11)1274-1283(2013 Nov)
Willer CJ,Schmidt EM,Sengupta S,Peloso GM,Gustafsson S,Kanoni S,Ganna A,Chen J,Buchkovich ML,Mora S,Beckmann JS,Bragg-Gresham JL,Chang HY,Demirkan A,Den Hertog HM,Do R,Donnelly LA,Ehret GB,Esko T,Feitosa MF,Ferreira T,Fischer K,Fontanillas P,Fraser RM,Freitag DF,Gurdasani D,Heikkil? K,Hypp?nen E,Isaacs A,Jackson AU,Johansson ?,Johnson T,Kaakinen M,Kettunen J,Kleber ME,Li X,Luan J,Lyytik?inen LP,Magnusson PKE,Mangino M,Mihailov E,Montasser ME,M?ller-Nurasyid M,Nolte IM,O'Connell JR,Palmer CD,Perola M,Petersen AK,Sanna S,Saxena R,Service SK,Shah S,Shungin D,Sidore C,Song C,Strawbridge RJ,Surakka I,Tanaka T,Teslovich TM,Thorleifsson G,Van den Herik EG,Voight BF,Volcik KA,Waite LL,Wong A,Wu Y,Zhang W,Absher D,Asiki G,Barroso I,Been LF,Bolton JL,Bonnycastle LL,Brambilla P,Burnett MS,Cesana G,Dimitriou M,Doney ASF,D?ring A,Elliott P,Epstein SE,Ingi Eyjolfsson G,Gigante B,Goodarzi MO,Grallert H,Gravito ML,Groves CJ,Hallmans G,Hartikainen AL,Hayward C,Hernandez D,Hicks AA,Holm H,Hung YJ,Illig T,Jones MR,Kaleebu P,Kastelein JJP,Khaw KT,Kim E,Klopp N,Komulainen P,Kumari M,Langenberg C,Lehtim?ki T,Lin SY,Lindstr?m J,Loos RJF,Mach F,McArdle WL,Meisinger C,Mitchell BD,M?ller G,Nagaraja R,Narisu N,Nieminen TVM,Nsubuga RN,Olafsson I,Ong KK,Palotie A,Papamarkou T,Pomilla C,Pouta A,Rader DJ,Reilly MP,Ridker PM,Rivadeneira F,Rudan I,Ruokonen A,Samani N,Scharnagl H,Seeley J,Silander K,Stan??kov? A,Stirrups K,Swift AJ,Tiret L,Uitterlinden AG,van Pelt LJ,Vedantam S,Wainwright N,Wijmenga C,Wild SH,Willemsen G,Wilsgaard T,Wilson JF,Young EH,Zhao JH,Adair LS,Arveiler D,Assimes TL,Bandinelli S,Bennett F,Bochud M,Boehm BO,Boomsma DI,Borecki IB,Bornstein SR,Bovet P,Burnier M,Campbell H,Chakravarti A,Chambers JC,Chen YI,Collins FS,Cooper RS,Danesh J,Dedoussis G,de Faire U,Feranil AB,Ferri?res J,Ferrucci L,Freimer NB,Gieger C,Groop LC,Gudnason V,Gyllensten U,Hamsten A,Harris TB,Hingorani A,Hirschhorn JN,Hofman A,Hovingh GK,Hsiung CA,Humphries SE,Hunt SC,Hveem K,Iribarren C,J?rvelin MR,Jula A,K?h?nen M,Kaprio J,Kes?niemi A,Kivimaki M,Kooner JS,Koudstaal PJ,Krauss RM,Kuh D,Kuusisto J,Kyvik KO,Laakso M,Lakka TA,Lind L,Lindgren CM,Martin NG,M?rz W,McCarthy MI,McKenzie CA,Meneton P,Metspalu A,Moilanen L,Morris AD,Munroe PB,Nj?lstad I,Pedersen NL,Power C,Pramstaller PP,Price JF,Psaty BM,Quertermous T,Rauramaa R,Saleheen D,Salomaa V,Sanghera DK,Saramies J,Schwarz PEH,Sheu WH,Shuldiner AR,Siegbahn A,Spector TD,Stefansson K,Strachan DP,Tayo BO,Tremoli E,Tuomilehto J,Uusitupa M,van Duijn CM,Vollenweider P,Wallentin L,Wareham NJ,Whitfield JB,Wolffenbuttel BHR,Ordovas JM,Boerwinkle E,Palmer CNA,Thorsteinsdottir U,Chasman DI,Rotter JI,Franks PW,Ripatti S,Cupples LA,Sandhu MS,Rich SS,Boehnke M,Deloukas P,Kathiresan S,Mohlke KL,Ingelsson E,Abecasis GR,

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ANGPTL1 cDNA ORF clone, Homo sapiens(human)

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Target ORF information:

ORF Insert Sequence:

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Target ORF information:

ORF Insert Sequence:

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Target ORF information:

ORF Insert Sequence:

Target ORF information:

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ORF Insert Sequence:

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