Gene Symbol | MAP3K14 |
Entrez Gene ID | 9020 |
Full Name | mitogen-activated protein kinase kinase kinase 14 |
Synonyms | FTDCR1B,HS,HSNIK,NIK |
General protein information |
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Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Summary | This gene encodes mitogen-activated protein kinase kinase kinase 14, which is a serine/threonine protein-kinase. This kinase binds to TRAF2 and stimulates NF-kappaB activity. It shares sequence similarity with several other MAPKK kinases. It participates in an NF-kappaB-inducing signalling cascade common to receptors of the tumour-necrosis/nerve-growth factor (TNF/NGF) family and to the interleukin-1 type-I receptor. [provided by RefSeq, Jul 2008]. |
Disorder MIM: |