Gene Symbol | TAF1B |
Entrez Gene ID | 9014 |
Full Name | TATA-box binding protein associated factor, RNA polymerase I subunit B |
Synonyms | MGC:9349,RAF1B,RAFI63,SL1,TAFI63 |
General protein information |
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Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Summary | Initiation of transcription by RNA polymerase I requires the formation of a complex composed of the TATA-binding protein (TBP) and three TBP-associated factors (TAFs) specific for RNA polymerase I. This complex, known as SL1, binds to the core promoter of ribosomal RNA genes to position the polymerase properly and acts as a channel for regulatory signals. This gene encodes one of the SL1-specific TAFs. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2016]. |
Disorder MIM: |