Gene Symbol | TAF1C |
Entrez Gene ID | 9013 |
Full Name | TATA-box binding protein associated factor, RNA polymerase I subunit C |
Synonyms | MGC:39976,SL1,TAFI110,TAFI95 |
General protein information |
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Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Summary | Initiation of transcription by RNA polymerase I requires the formation of a complex composed of the TATA-binding protein (TBP) and three TBP-associated factors (TAFs) specific for RNA polymerase I. This complex, known as SL1, binds to the core promoter of ribosomal RNA genes to position the polymerase properly and acts as a channel for regulatory signals. This gene encodes the largest SL1-specific TAF. Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2011]. |
Disorder MIM: |