SERPINB11 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	SERPINB11
Entrez Gene ID	89778
Full Name	serpin family B member 11 (gene/pseudogene)
Synonyms	EPIPIN,SERPIN11
General protein information	Preferred Names serpin family B member 11 (gene/pseudogene) Names serpin B11 serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 11 serpin peptidase inhibitor, clade B (ovalbumin), member 11
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 18 Map Location: 18q21.33
Disorder MIM:	615682

mRNA and Protein(s)

mRNA	Protein	Name
XM_011526251.1	XP_011524553.1	serpin B11 isoform X1
NM_001291279.2	NP_001278208.1	serpin B11 isoform c
NM_001291278.2	NP_001278207.1	serpin B11 isoform b
NM_080475.4	NP_536723.2	serpin B11 isoform a
NM_080475.3	NP_536723.2	serpin B11 isoform a
NM_001291278.1	NP_001278207.1	serpin B11 isoform b
NM_001291279.1	NP_001278208.1	serpin B11 isoform c
NM_001370475.1	NP_001357404.1	serpin B11 isoform a

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	SERPINB11	XP_005615396.1
Rattus norvegicus (Norway rat)	Serpinb11	NP_001100637.1
Homo sapiens (human)	SERPINB11	NP_536723.2
Pan troglodytes (chimpanzee)	SERPINB11	XP_523958.3
	SERPINB11	XP_001091618.1
Mus musculus (house mouse)	Serpinb11	NP_080143.1
Xenopus tropicalis (tropical clawed frog)	LOC100490487	XP_002936466.1

Gene Ontology
Bibliography

Related articles in PubMed

Update of the human and mouse SERPIN gene superfamily.
Heit C, Jackson BC, McAndrews M, Wright MW, Thompson DC, Silverman GA, Nebert DW, Vasiliou V
Human genomics722(2013 Oct)

Avian SERPINB11 gene: a marker for ovarian endometrioid cancer in chickens.
Lim W, Kim JH, Ahn SE, Jeong W, Kim J, Bazer FW, Han JY, Song G
Experimental biology and medicine (Maywood, N.J.)237(2)150-9(2012 Feb)

Loss and gain of function in SERPINB11: an example of a gene under selection on standing variation, with implications for host-pathogen interactions.
Seixas S, Ivanova N, Ferreira Z, Rocha J, Victor BL
PloS one7(2)e32518(2012)

SERPINB11 is a new noninhibitory intracellular serpin. Common single nucleotide polymorphisms in the scaffold impair conformational change.
Askew DJ, Cataltepe S, Kumar V, Edwards C, Pace SM, Howarth RN, Pak SC, Askew YS, Br?mme D, Luke CJ, Whisstock JC, Silverman GA
The Journal of biological chemistry282(34)24948-60(2007 Aug)

Prominent use of distal 5' transcription start sites and discovery of a large number of additional exons in ENCODE regions.
Denoeud F, Kapranov P, Ucla C, Frankish A, Castelo R, Drenkow J, Lagarde J, Alioto T, Manzano C, Chrast J, Dike S, Wyss C, Henrichsen CN, Holroyd N, Dickson MC, Taylor R, Hance Z, Foissac S, Myers RM, Rogers J, Hubbard T, Harrow J, Guig? R, Gingeras TR, Antonarakis SE, Reymond A
Genome research17(6)746-59(2007 Jun)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

SERPINB11 has a role in ovarian endometrioid carcinoma in chickens and human
Title: Avian SERPINB11 gene: a marker for ovarian endometrioid cancer in chickens.

SERPINB11 is a gene under selection on standing variation, with roles in host-pathogen interactions
Title: Loss and gain of function in SERPINB11: an example of a gene under selection on standing variation, with implications for host-pathogen interactions.

SERPINB11 is a new noninhibitory intracellular serpin
Title: SERPINB11 is a new noninhibitory intracellular serpin. Common single nucleotide polymorphisms in the scaffold impair conformational change.

The following SERPINB11 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the SERPINB11 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu14429	NM_080475.4 Latest version!	Homo sapiens serpin family B member 11 (gene/pseudogene) (SERPINB11), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
OHu14429	NM_001370475.1 Latest version!	Homo sapiens serpin family B member 11 (gene/pseudogene) (SERPINB11), transcript variant 4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
OHu14429	XM_011526251.1 Latest version!	Homo sapiens serpin family B member 11 (gene/pseudogene) (SERPINB11), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
OHu14436	NM_001291279.2 Latest version!	Homo sapiens serpin family B member 11 (gene/pseudogene) (SERPINB11), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$139.30 $199.00
OHu14434	NM_001291278.2 Latest version!	Homo sapiens serpin family B member 11 (gene/pseudogene) (SERPINB11), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
View Old Accession Versions >>
OHu14429	NM_080475.3	Homo sapiens serpin family B member 11 (gene/pseudogene) (SERPINB11), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
OHu14434	NM_001291278.1	Homo sapiens serpin family B member 11 (gene/pseudogene) (SERPINB11), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
OHu14436	NM_001291279.1	Homo sapiens serpin family B member 11 (gene/pseudogene) (SERPINB11), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$139.30 $199.00
Hide Old Accession Versions >>

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***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

SERPINB11 ( NM_080475.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_536723.2 Homo sapiens serpin family B member 11 (gene/pseudogene) (SERPINB11), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu14429
Clone ID Related Accession (Same CDS sequence)	XM_011526251.1 , NM_080475.4 , NM_080475.3 , NM_001370475.1
Accession Version	NM_080475.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1179bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-06-03
Organism	Homo sapiens(human)
Product	serpin B11 isoform a
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC069356.6 and KF459701.1. On May 8, 2019 this sequence version replaced NM_080475.3. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: AY739645.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2159368, SAMN03465411 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## polymorphic pseudogene :: PMID: 22393410 ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGGTTCTC TCAGCACAGC TAACGTTGAA TTTTGCCTTG ATGTGTTCAA AGAGCTGAAC 
AGTAACAACA TAGGAGATAA CATCTTCTTT TCTTCGCTGA GTCTGCTTTA TGCTCTAAGC 
ATGGTCCTCC TTGGTGCCAG GGGAGAGACT GAAGAGCAAT TGGAGAAGGT GCTTCATTTT 
AGTCATACTG TAGACTCATT AAAACCAGGG TTCAAGGACT CACCTAAGTG CAGCCAAGCT 
GGAAGAATTC ATTCCGAGTT TGGTGTCGAA TTCTCTCAAA TCAACCAGCC AGACTCTAAC 
TGTACCCTCA GCATTGCCAA CAGGCTCTAC GGGACAAAGA CGATGGCATT TCATCAGCAA 
TATTTAAGCT GTTCTGAGAA ATGGTATCAA GCCAGGTTGC AAACTGTGGA TTTTGAACAG 
TCTACAGAAG AAACGAGGAA AACGATTAAT GCTTGGGTTG AAAATAAAAC TAATGGAAAA 
GTCGCAAATC TCTTTGGAAA GAGCACAATT GACCCTTCAT CTGTAATGGT CCTGGTGAAT 
GCCATATATT TCAAAGGACA ATGGCAAAAT AAATTTCAAG TAAGAGAGAC AGTTAAAAGT 
CCTTTTCAGC TAAGTGAGGG TAAAAATGTA ACTGTGGAAA TGATGTATCA AATTGGAACA 
TTTAAACTGG CCTTTGTAAA GGAGCCGCAG ATGCAAGTTC TTGAGCTGCC CTACGTTAAC 
AACAAATTAA GCATGATTAT TCTGCTTCCA GTAGGCATAG CTAATCTGAA ACAGATAGAA 
AAGCAGCTGA ATTCGGGGAC GTTTCATGAG TGGACAAGCT CTTCTAACAT GATGGAAAGA 
GAAGTTGAAG TACACCTCCC CCGATTCAAA CTTGAAACTA AGTATGAGCT AAATTCCCTG 
TTAAAATCTC TAGGGGTGAC AGATCTCTTC AACCAGGTCA AAGCTGATCT TTCTGGAATG 
TCACCAACCA AGGGCCTATA TTTATCAAAA GCCATCCACA AGTCATACCT GGATGTCAGC 
GAAGAGGGCA CGGAGGCAGC AGCAGCCACT GGGGACAGCA TCGCTGTAAA AAGCCTACCA 
ATGAGAGCTC AGTTCAAGGC GAACCACCCC TTCCTTTTCT TTATAAGGCA CACTCATACC 
AACACGATCC TATTCTGTGG CAAGCTTGCC TCTCCCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_536723.2
CDS	243..1421
Translation	MGSLSTANVEFCLDVFKELNSNNIGDNIFFSSLSLLYALSMVLLGARGETEEQLEKVLHFSHTVDSLKPGFKDSPKCSQAGRIHSEFGVEFSQINQPDSNCTLSIANRLYGTKTMAFHQQYLSCSEKWYQARLQTVDFEQSTEETRKTINAWVENKTNGKVANLFGKSTIDPSSVMVLVNAIYFKGQWQNKFQVRETVKSPFQLSEGKNVTVEMMYQIGTFKLAFVKEPQMQVLELPYVNNKLSMIILLPVGIANLKQIEKQLNSGTFHEWTSSSNMMEREVEVHLPRFKLETKYELNSLLKSLGVTDLFNQVKADLSGMSPTKGLYLSKAIHKSYLDVSEEGTEAAAATGDSIAVKSLPMRAQFKANHPFLFFIRHTHTNTILFCGKLASP

Target ORF information:

RefSeq Version	NM_080475.4
Organism	Homo sapiens(human)
Definition	Homo sapiens serpin family B member 11 (gene/pseudogene) (SERPINB11), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_080475.4

ORF Insert Sequence:

ATGGGTTCTC TCAGCACAGC TAACGTTGAA TTTTGCCTTG ATGTGTTCAA AGAGCTGAAC 
AGTAACAACA TAGGAGATAA CATCTTCTTT TCTTCGCTGA GTCTGCTTTA TGCTCTAAGC 
ATGGTCCTCC TTGGTGCCAG GGGAGAGACT GAAGAGCAAT TGGAGAAGGT GCTTCATTTT 
AGTCATACTG TAGACTCATT AAAACCAGGG TTCAAGGACT CACCTAAGTG CAGCCAAGCT 
GGAAGAATTC ATTCCGAGTT TGGTGTCGAA TTCTCTCAAA TCAACCAGCC AGACTCTAAC 
TGTACCCTCA GCATTGCCAA CAGGCTCTAC GGGACAAAGA CGATGGCATT TCATCAGCAA 
TATTTAAGCT GTTCTGAGAA ATGGTATCAA GCCAGGTTGC AAACTGTGGA TTTTGAACAG 
TCTACAGAAG AAACGAGGAA AACGATTAAT GCTTGGGTTG AAAATAAAAC TAATGGAAAA 
GTCGCAAATC TCTTTGGAAA GAGCACAATT GACCCTTCAT CTGTAATGGT CCTGGTGAAT 
GCCATATATT TCAAAGGACA ATGGCAAAAT AAATTTCAAG TAAGAGAGAC AGTTAAAAGT 
CCTTTTCAGC TAAGTGAGGG TAAAAATGTA ACTGTGGAAA TGATGTATCA AATTGGAACA 
TTTAAACTGG CCTTTGTAAA GGAGCCGCAG ATGCAAGTTC TTGAGCTGCC CTACGTTAAC 
AACAAATTAA GCATGATTAT TCTGCTTCCA GTAGGCATAG CTAATCTGAA ACAGATAGAA 
AAGCAGCTGA ATTCGGGGAC GTTTCATGAG TGGACAAGCT CTTCTAACAT GATGGAAAGA 
GAAGTTGAAG TACACCTCCC CCGATTCAAA CTTGAAACTA AGTATGAGCT AAATTCCCTG 
TTAAAATCTC TAGGGGTGAC AGATCTCTTC AACCAGGTCA AAGCTGATCT TTCTGGAATG 
TCACCAACCA AGGGCCTATA TTTATCAAAA GCCATCCACA AGTCATACCT GGATGTCAGC 
GAAGAGGGCA CGGAGGCAGC AGCAGCCACT GGGGACAGCA TCGCTGTAAA AAGCCTACCA 
ATGAGAGCTC AGTTCAAGGC GAACCACCCC TTCCTTTTCT TTATAAGGCA CACTCATACC 
AACACGATCC TATTCTGTGG CAAGCTTGCC TCTCCCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SERPINB11 ( NM_080475.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_536723.2 Homo sapiens serpin family B member 11 (gene/pseudogene) (SERPINB11), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu14429
Clone ID Related Accession (Same CDS sequence)	XM_011526251.1 , NM_080475.4 , NM_080475.3 , NM_001370475.1
Accession Version	NM_080475.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1179bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-06-29
Organism	Homo sapiens(human)
Product	serpin B11 isoform a
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC069356.6, AY739645.1, DC383104.1, AF419954.1 and AY792323.1. On Apr 1, 2014 this sequence version replaced NM_080475.2. Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (a). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: AY739645.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2159368, SAMN03465411 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## polymorphic pseudogene :: PMID: 22393410 ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGGTTCTC TCAGCACAGC TAACGTTGAA TTTTGCCTTG ATGTGTTCAA AGAGCTGAAC 
AGTAACAACA TAGGAGATAA CATCTTCTTT TCTTCGCTGA GTCTGCTTTA TGCTCTAAGC 
ATGGTCCTCC TTGGTGCCAG GGGAGAGACT GAAGAGCAAT TGGAGAAGGT GCTTCATTTT 
AGTCATACTG TAGACTCATT AAAACCAGGG TTCAAGGACT CACCTAAGTG CAGCCAAGCT 
GGAAGAATTC ATTCCGAGTT TGGTGTCGAA TTCTCTCAAA TCAACCAGCC AGACTCTAAC 
TGTACCCTCA GCATTGCCAA CAGGCTCTAC GGGACAAAGA CGATGGCATT TCATCAGCAA 
TATTTAAGCT GTTCTGAGAA ATGGTATCAA GCCAGGTTGC AAACTGTGGA TTTTGAACAG 
TCTACAGAAG AAACGAGGAA AACGATTAAT GCTTGGGTTG AAAATAAAAC TAATGGAAAA 
GTCGCAAATC TCTTTGGAAA GAGCACAATT GACCCTTCAT CTGTAATGGT CCTGGTGAAT 
GCCATATATT TCAAAGGACA ATGGCAAAAT AAATTTCAAG TAAGAGAGAC AGTTAAAAGT 
CCTTTTCAGC TAAGTGAGGG TAAAAATGTA ACTGTGGAAA TGATGTATCA AATTGGAACA 
TTTAAACTGG CCTTTGTAAA GGAGCCGCAG ATGCAAGTTC TTGAGCTGCC CTACGTTAAC 
AACAAATTAA GCATGATTAT TCTGCTTCCA GTAGGCATAG CTAATCTGAA ACAGATAGAA 
AAGCAGCTGA ATTCGGGGAC GTTTCATGAG TGGACAAGCT CTTCTAACAT GATGGAAAGA 
GAAGTTGAAG TACACCTCCC CCGATTCAAA CTTGAAACTA AGTATGAGCT AAATTCCCTG 
TTAAAATCTC TAGGGGTGAC AGATCTCTTC AACCAGGTCA AAGCTGATCT TTCTGGAATG 
TCACCAACCA AGGGCCTATA TTTATCAAAA GCCATCCACA AGTCATACCT GGATGTCAGC 
GAAGAGGGCA CGGAGGCAGC AGCAGCCACT GGGGACAGCA TCGCTGTAAA AAGCCTACCA 
ATGAGAGCTC AGTTCAAGGC GAACCACCCC TTCCTTTTCT TTATAAGGCA CACTCATACC 
AACACGATCC TATTCTGTGG CAAGCTTGCC TCTCCCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_536723.2
CDS	246..1424
Translation	MGSLSTANVEFCLDVFKELNSNNIGDNIFFSSLSLLYALSMVLLGARGETEEQLEKVLHFSHTVDSLKPGFKDSPKCSQAGRIHSEFGVEFSQINQPDSNCTLSIANRLYGTKTMAFHQQYLSCSEKWYQARLQTVDFEQSTEETRKTINAWVENKTNGKVANLFGKSTIDPSSVMVLVNAIYFKGQWQNKFQVRETVKSPFQLSEGKNVTVEMMYQIGTFKLAFVKEPQMQVLELPYVNNKLSMIILLPVGIANLKQIEKQLNSGTFHEWTSSSNMMEREVEVHLPRFKLETKYELNSLLKSLGVTDLFNQVKADLSGMSPTKGLYLSKAIHKSYLDVSEEGTEAAAATGDSIAVKSLPMRAQFKANHPFLFFIRHTHTNTILFCGKLASP

Target ORF information:

RefSeq Version	NM_080475.3
Organism	Homo sapiens(human)
Definition	Homo sapiens serpin family B member 11 (gene/pseudogene) (SERPINB11), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_080475.3

ORF Insert Sequence:

ATGGGTTCTC TCAGCACAGC TAACGTTGAA TTTTGCCTTG ATGTGTTCAA AGAGCTGAAC 
AGTAACAACA TAGGAGATAA CATCTTCTTT TCTTCGCTGA GTCTGCTTTA TGCTCTAAGC 
ATGGTCCTCC TTGGTGCCAG GGGAGAGACT GAAGAGCAAT TGGAGAAGGT GCTTCATTTT 
AGTCATACTG TAGACTCATT AAAACCAGGG TTCAAGGACT CACCTAAGTG CAGCCAAGCT 
GGAAGAATTC ATTCCGAGTT TGGTGTCGAA TTCTCTCAAA TCAACCAGCC AGACTCTAAC 
TGTACCCTCA GCATTGCCAA CAGGCTCTAC GGGACAAAGA CGATGGCATT TCATCAGCAA 
TATTTAAGCT GTTCTGAGAA ATGGTATCAA GCCAGGTTGC AAACTGTGGA TTTTGAACAG 
TCTACAGAAG AAACGAGGAA AACGATTAAT GCTTGGGTTG AAAATAAAAC TAATGGAAAA 
GTCGCAAATC TCTTTGGAAA GAGCACAATT GACCCTTCAT CTGTAATGGT CCTGGTGAAT 
GCCATATATT TCAAAGGACA ATGGCAAAAT AAATTTCAAG TAAGAGAGAC AGTTAAAAGT 
CCTTTTCAGC TAAGTGAGGG TAAAAATGTA ACTGTGGAAA TGATGTATCA AATTGGAACA 
TTTAAACTGG CCTTTGTAAA GGAGCCGCAG ATGCAAGTTC TTGAGCTGCC CTACGTTAAC 
AACAAATTAA GCATGATTAT TCTGCTTCCA GTAGGCATAG CTAATCTGAA ACAGATAGAA 
AAGCAGCTGA ATTCGGGGAC GTTTCATGAG TGGACAAGCT CTTCTAACAT GATGGAAAGA 
GAAGTTGAAG TACACCTCCC CCGATTCAAA CTTGAAACTA AGTATGAGCT AAATTCCCTG 
TTAAAATCTC TAGGGGTGAC AGATCTCTTC AACCAGGTCA AAGCTGATCT TTCTGGAATG 
TCACCAACCA AGGGCCTATA TTTATCAAAA GCCATCCACA AGTCATACCT GGATGTCAGC 
GAAGAGGGCA CGGAGGCAGC AGCAGCCACT GGGGACAGCA TCGCTGTAAA AAGCCTACCA 
ATGAGAGCTC AGTTCAAGGC GAACCACCCC TTCCTTTTCT TTATAAGGCA CACTCATACC 
AACACGATCC TATTCTGTGG CAAGCTTGCC TCTCCCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SERPINB11 ( NM_001370475.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001357404.1 Homo sapiens serpin family B member 11 (gene/pseudogene) (SERPINB11), transcript variant 4, mRNA.

Price & Availability↑

CloneID	OHu14429
Clone ID Related Accession (Same CDS sequence)	XM_011526251.1 , NM_080475.4 , NM_080475.3 , NM_001370475.1
Accession Version	NM_001370475.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1179bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-06
Organism	Homo sapiens(human)
Product	serpin B11 isoform a
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC069356.6 and KF459701.1. On May 8, 2019 this sequence version replaced XM_011526251.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: AK292775.1, AY739645.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2144335, SAMEA2147975 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## polymorphic pseudogene :: PMID: 22393410 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END##

ATGGGTTCTC TCAGCACAGC TAACGTTGAA TTTTGCCTTG ATGTGTTCAA AGAGCTGAAC 
AGTAACAACA TAGGAGATAA CATCTTCTTT TCTTCGCTGA GTCTGCTTTA TGCTCTAAGC 
ATGGTCCTCC TTGGTGCCAG GGGAGAGACT GAAGAGCAAT TGGAGAAGGT GCTTCATTTT 
AGTCATACTG TAGACTCATT AAAACCAGGG TTCAAGGACT CACCTAAGTG CAGCCAAGCT 
GGAAGAATTC ATTCCGAGTT TGGTGTCGAA TTCTCTCAAA TCAACCAGCC AGACTCTAAC 
TGTACCCTCA GCATTGCCAA CAGGCTCTAC GGGACAAAGA CGATGGCATT TCATCAGCAA 
TATTTAAGCT GTTCTGAGAA ATGGTATCAA GCCAGGTTGC AAACTGTGGA TTTTGAACAG 
TCTACAGAAG AAACGAGGAA AACGATTAAT GCTTGGGTTG AAAATAAAAC TAATGGAAAA 
GTCGCAAATC TCTTTGGAAA GAGCACAATT GACCCTTCAT CTGTAATGGT CCTGGTGAAT 
GCCATATATT TCAAAGGACA ATGGCAAAAT AAATTTCAAG TAAGAGAGAC AGTTAAAAGT 
CCTTTTCAGC TAAGTGAGGG TAAAAATGTA ACTGTGGAAA TGATGTATCA AATTGGAACA 
TTTAAACTGG CCTTTGTAAA GGAGCCGCAG ATGCAAGTTC TTGAGCTGCC CTACGTTAAC 
AACAAATTAA GCATGATTAT TCTGCTTCCA GTAGGCATAG CTAATCTGAA ACAGATAGAA 
AAGCAGCTGA ATTCGGGGAC GTTTCATGAG TGGACAAGCT CTTCTAACAT GATGGAAAGA 
GAAGTTGAAG TACACCTCCC CCGATTCAAA CTTGAAACTA AGTATGAGCT AAATTCCCTG 
TTAAAATCTC TAGGGGTGAC AGATCTCTTC AACCAGGTCA AAGCTGATCT TTCTGGAATG 
TCACCAACCA AGGGCCTATA TTTATCAAAA GCCATCCACA AGTCATACCT GGATGTCAGC 
GAAGAGGGCA CGGAGGCAGC AGCAGCCACT GGGGACAGCA TCGCTGTAAA AAGCCTACCA 
ATGAGAGCTC AGTTCAAGGC GAACCACCCC TTCCTTTTCT TTATAAGGCA CACTCATACC 
AACACGATCC TATTCTGTGG CAAGCTTGCC TCTCCCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001357404.1
CDS	63..1241
Translation	MGSLSTANVEFCLDVFKELNSNNIGDNIFFSSLSLLYALSMVLLGARGETEEQLEKVLHFSHTVDSLKPGFKDSPKCSQAGRIHSEFGVEFSQINQPDSNCTLSIANRLYGTKTMAFHQQYLSCSEKWYQARLQTVDFEQSTEETRKTINAWVENKTNGKVANLFGKSTIDPSSVMVLVNAIYFKGQWQNKFQVRETVKSPFQLSEGKNVTVEMMYQIGTFKLAFVKEPQMQVLELPYVNNKLSMIILLPVGIANLKQIEKQLNSGTFHEWTSSSNMMEREVEVHLPRFKLETKYELNSLLKSLGVTDLFNQVKADLSGMSPTKGLYLSKAIHKSYLDVSEEGTEAAAATGDSIAVKSLPMRAQFKANHPFLFFIRHTHTNTILFCGKLASP

Target ORF information:

RefSeq Version	NM_001370475.1
Organism	Homo sapiens(human)
Definition	Homo sapiens serpin family B member 11 (gene/pseudogene) (SERPINB11), transcript variant 4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001370475.1

ORF Insert Sequence:

ATGGGTTCTC TCAGCACAGC TAACGTTGAA TTTTGCCTTG ATGTGTTCAA AGAGCTGAAC 
AGTAACAACA TAGGAGATAA CATCTTCTTT TCTTCGCTGA GTCTGCTTTA TGCTCTAAGC 
ATGGTCCTCC TTGGTGCCAG GGGAGAGACT GAAGAGCAAT TGGAGAAGGT GCTTCATTTT 
AGTCATACTG TAGACTCATT AAAACCAGGG TTCAAGGACT CACCTAAGTG CAGCCAAGCT 
GGAAGAATTC ATTCCGAGTT TGGTGTCGAA TTCTCTCAAA TCAACCAGCC AGACTCTAAC 
TGTACCCTCA GCATTGCCAA CAGGCTCTAC GGGACAAAGA CGATGGCATT TCATCAGCAA 
TATTTAAGCT GTTCTGAGAA ATGGTATCAA GCCAGGTTGC AAACTGTGGA TTTTGAACAG 
TCTACAGAAG AAACGAGGAA AACGATTAAT GCTTGGGTTG AAAATAAAAC TAATGGAAAA 
GTCGCAAATC TCTTTGGAAA GAGCACAATT GACCCTTCAT CTGTAATGGT CCTGGTGAAT 
GCCATATATT TCAAAGGACA ATGGCAAAAT AAATTTCAAG TAAGAGAGAC AGTTAAAAGT 
CCTTTTCAGC TAAGTGAGGG TAAAAATGTA ACTGTGGAAA TGATGTATCA AATTGGAACA 
TTTAAACTGG CCTTTGTAAA GGAGCCGCAG ATGCAAGTTC TTGAGCTGCC CTACGTTAAC 
AACAAATTAA GCATGATTAT TCTGCTTCCA GTAGGCATAG CTAATCTGAA ACAGATAGAA 
AAGCAGCTGA ATTCGGGGAC GTTTCATGAG TGGACAAGCT CTTCTAACAT GATGGAAAGA 
GAAGTTGAAG TACACCTCCC CCGATTCAAA CTTGAAACTA AGTATGAGCT AAATTCCCTG 
TTAAAATCTC TAGGGGTGAC AGATCTCTTC AACCAGGTCA AAGCTGATCT TTCTGGAATG 
TCACCAACCA AGGGCCTATA TTTATCAAAA GCCATCCACA AGTCATACCT GGATGTCAGC 
GAAGAGGGCA CGGAGGCAGC AGCAGCCACT GGGGACAGCA TCGCTGTAAA AAGCCTACCA 
ATGAGAGCTC AGTTCAAGGC GAACCACCCC TTCCTTTTCT TTATAAGGCA CACTCATACC 
AACACGATCC TATTCTGTGG CAAGCTTGCC TCTCCCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SERPINB11 ( XM_011526251.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_011524553.1 Homo sapiens serpin family B member 11 (gene/pseudogene) (SERPINB11), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu14429
Clone ID Related Accession (Same CDS sequence)	XM_011526251.1 , NM_080475.4 , NM_080475.3 , NM_001370475.1
Accession Version	XM_011526251.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1179bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-03-25
Organism	Homo sapiens(human)
Product	serpin B11 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000018.10) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Homo sapiens Annotation Release 109 Annotation Version :: 109 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGTTCTC TCAGCACAGC TAACGTTGAA TTTTGCCTTG ATGTGTTCAA AGAGCTGAAC 
AGTAACAACA TAGGAGATAA CATCTTCTTT TCTTCGCTGA GTCTGCTTTA TGCTCTAAGC 
ATGGTCCTCC TTGGTGCCAG GGGAGAGACT GAAGAGCAAT TGGAGAAGGT GCTTCATTTT 
AGTCATACTG TAGACTCATT AAAACCAGGG TTCAAGGACT CACCTAAGTG CAGCCAAGCT 
GGAAGAATTC ATTCCGAGTT TGGTGTCGAA TTCTCTCAAA TCAACCAGCC AGACTCTAAC 
TGTACCCTCA GCATTGCCAA CAGGCTCTAC GGGACAAAGA CGATGGCATT TCATCAGCAA 
TATTTAAGCT GTTCTGAGAA ATGGTATCAA GCCAGGTTGC AAACTGTGGA TTTTGAACAG 
TCTACAGAAG AAACGAGGAA AACGATTAAT GCTTGGGTTG AAAATAAAAC TAATGGAAAA 
GTCGCAAATC TCTTTGGAAA GAGCACAATT GACCCTTCAT CTGTAATGGT CCTGGTGAAT 
GCCATATATT TCAAAGGACA ATGGCAAAAT AAATTTCAAG TAAGAGAGAC AGTTAAAAGT 
CCTTTTCAGC TAAGTGAGGG TAAAAATGTA ACTGTGGAAA TGATGTATCA AATTGGAACA 
TTTAAACTGG CCTTTGTAAA GGAGCCGCAG ATGCAAGTTC TTGAGCTGCC CTACGTTAAC 
AACAAATTAA GCATGATTAT TCTGCTTCCA GTAGGCATAG CTAATCTGAA ACAGATAGAA 
AAGCAGCTGA ATTCGGGGAC GTTTCATGAG TGGACAAGCT CTTCTAACAT GATGGAAAGA 
GAAGTTGAAG TACACCTCCC CCGATTCAAA CTTGAAACTA AGTATGAGCT AAATTCCCTG 
TTAAAATCTC TAGGGGTGAC AGATCTCTTC AACCAGGTCA AAGCTGATCT TTCTGGAATG 
TCACCAACCA AGGGCCTATA TTTATCAAAA GCCATCCACA AGTCATACCT GGATGTCAGC 
GAAGAGGGCA CGGAGGCAGC AGCAGCCACT GGGGACAGCA TCGCTGTAAA AAGCCTACCA 
ATGAGAGCTC AGTTCAAGGC GAACCACCCC TTCCTTTTCT TTATAAGGCA CACTCATACC 
AACACGATCC TATTCTGTGG CAAGCTTGCC TCTCCCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011524553.1
CDS	287..1465
Translation	MGSLSTANVEFCLDVFKELNSNNIGDNIFFSSLSLLYALSMVLLGARGETEEQLEKVLHFSHTVDSLKPGFKDSPKCSQAGRIHSEFGVEFSQINQPDSNCTLSIANRLYGTKTMAFHQQYLSCSEKWYQARLQTVDFEQSTEETRKTINAWVENKTNGKVANLFGKSTIDPSSVMVLVNAIYFKGQWQNKFQVRETVKSPFQLSEGKNVTVEMMYQIGTFKLAFVKEPQMQVLELPYVNNKLSMIILLPVGIANLKQIEKQLNSGTFHEWTSSSNMMEREVEVHLPRFKLETKYELNSLLKSLGVTDLFNQVKADLSGMSPTKGLYLSKAIHKSYLDVSEEGTEAAAATGDSIAVKSLPMRAQFKANHPFLFFIRHTHTNTILFCGKLASP

Target ORF information:

RefSeq Version	XM_011526251.1
Organism	Homo sapiens(human)
Definition	Homo sapiens serpin family B member 11 (gene/pseudogene) (SERPINB11), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011526251.1

ORF Insert Sequence:

ATGGGTTCTC TCAGCACAGC TAACGTTGAA TTTTGCCTTG ATGTGTTCAA AGAGCTGAAC 
AGTAACAACA TAGGAGATAA CATCTTCTTT TCTTCGCTGA GTCTGCTTTA TGCTCTAAGC 
ATGGTCCTCC TTGGTGCCAG GGGAGAGACT GAAGAGCAAT TGGAGAAGGT GCTTCATTTT 
AGTCATACTG TAGACTCATT AAAACCAGGG TTCAAGGACT CACCTAAGTG CAGCCAAGCT 
GGAAGAATTC ATTCCGAGTT TGGTGTCGAA TTCTCTCAAA TCAACCAGCC AGACTCTAAC 
TGTACCCTCA GCATTGCCAA CAGGCTCTAC GGGACAAAGA CGATGGCATT TCATCAGCAA 
TATTTAAGCT GTTCTGAGAA ATGGTATCAA GCCAGGTTGC AAACTGTGGA TTTTGAACAG 
TCTACAGAAG AAACGAGGAA AACGATTAAT GCTTGGGTTG AAAATAAAAC TAATGGAAAA 
GTCGCAAATC TCTTTGGAAA GAGCACAATT GACCCTTCAT CTGTAATGGT CCTGGTGAAT 
GCCATATATT TCAAAGGACA ATGGCAAAAT AAATTTCAAG TAAGAGAGAC AGTTAAAAGT 
CCTTTTCAGC TAAGTGAGGG TAAAAATGTA ACTGTGGAAA TGATGTATCA AATTGGAACA 
TTTAAACTGG CCTTTGTAAA GGAGCCGCAG ATGCAAGTTC TTGAGCTGCC CTACGTTAAC 
AACAAATTAA GCATGATTAT TCTGCTTCCA GTAGGCATAG CTAATCTGAA ACAGATAGAA 
AAGCAGCTGA ATTCGGGGAC GTTTCATGAG TGGACAAGCT CTTCTAACAT GATGGAAAGA 
GAAGTTGAAG TACACCTCCC CCGATTCAAA CTTGAAACTA AGTATGAGCT AAATTCCCTG 
TTAAAATCTC TAGGGGTGAC AGATCTCTTC AACCAGGTCA AAGCTGATCT TTCTGGAATG 
TCACCAACCA AGGGCCTATA TTTATCAAAA GCCATCCACA AGTCATACCT GGATGTCAGC 
GAAGAGGGCA CGGAGGCAGC AGCAGCCACT GGGGACAGCA TCGCTGTAAA AAGCCTACCA 
ATGAGAGCTC AGTTCAAGGC GAACCACCCC TTCCTTTTCT TTATAAGGCA CACTCATACC 
AACACGATCC TATTCTGTGG CAAGCTTGCC TCTCCCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SERPINB11 ( NM_001291279.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001278208.1 Homo sapiens serpin family B member 11 (gene/pseudogene) (SERPINB11), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu14436
Clone ID Related Accession (Same CDS sequence)	NM_001291279.2 , NM_001291279.1
Accession Version	NM_001291279.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 654bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-05-07
Organism	Homo sapiens(human)
Product	serpin B11 isoform c
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC069356.6 and KF459701.1. On May 8, 2019 this sequence version replaced NM_001291279.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: AK296705.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2144335, SAMEA2147975 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## polymorphic pseudogene :: PMID: 22393410 ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGTCCTGG TGAATGCCAT ATATTTCAAA GGACAATGGC AAAATAAATT TCAAGTAAGA 
GAGACAGTTA AAAGTCCTTT TCAGCTAAGT GAGGGTAAAA ATGTAACTGT GGAAATGATG 
TATCAAATTG GAACATTTAA ACTGGCCTTT GTAAAGGAGC CGCAGATGCA AGTTCTTGAG 
CTGCCCTACG TTAACAACAA ATTAAGCATG ATTATTCTGC TTCCAGTAGG CATAGCTAAT 
CTGAAACAGA TAGAAAAGCA GCTGAATTCG GGGACGTTTC ATGAGTGGAC AAGCTCTTCT 
AACATGATGG AAAGAGAAGT TGAAGTACAC CTCCCCCGAT TCAAACTTGA AACTAAGTAT 
GAGCTAAATT CCCTGTTAAA ATCTCTAGGG GTGACAGATC TCTTCAACCA GGTCAAAGCT 
GATCTTTCTG GAATGTCACC AACCAAGGGC CTATATTTAT CAAAAGCCAT CCACAAGTCA 
TACCTGGATG TCAGCGAAGA GGGCACGGAG GCAGCAGCAG CCACTGGGGA CAGCATCGCT 
GTAAAAAGCC TACCAATGAG AGCTCAGTTC AAGGCGAACC ACCCCTTCCT TTTCTTTATA 
AGGCACACTC ATACCAACAC GATCCTATTC TGTGGCAAGC TTGCCTCTCC CTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001278208.1
CDS	470..1123
Translation	MVLVNAIYFKGQWQNKFQVRETVKSPFQLSEGKNVTVEMMYQIGTFKLAFVKEPQMQVLELPYVNNKLSMIILLPVGIANLKQIEKQLNSGTFHEWTSSSNMMEREVEVHLPRFKLETKYELNSLLKSLGVTDLFNQVKADLSGMSPTKGLYLSKAIHKSYLDVSEEGTEAAAATGDSIAVKSLPMRAQFKANHPFLFFIRHTHTNTILFCGKLASP

Target ORF information:

RefSeq Version	NM_001291279.2
Organism	Homo sapiens(human)
Definition	Homo sapiens serpin family B member 11 (gene/pseudogene) (SERPINB11), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001291279.2

ORF Insert Sequence:

ATGGTCCTGG TGAATGCCAT ATATTTCAAA GGACAATGGC AAAATAAATT TCAAGTAAGA 
GAGACAGTTA AAAGTCCTTT TCAGCTAAGT GAGGGTAAAA ATGTAACTGT GGAAATGATG 
TATCAAATTG GAACATTTAA ACTGGCCTTT GTAAAGGAGC CGCAGATGCA AGTTCTTGAG 
CTGCCCTACG TTAACAACAA ATTAAGCATG ATTATTCTGC TTCCAGTAGG CATAGCTAAT 
CTGAAACAGA TAGAAAAGCA GCTGAATTCG GGGACGTTTC ATGAGTGGAC AAGCTCTTCT 
AACATGATGG AAAGAGAAGT TGAAGTACAC CTCCCCCGAT TCAAACTTGA AACTAAGTAT 
GAGCTAAATT CCCTGTTAAA ATCTCTAGGG GTGACAGATC TCTTCAACCA GGTCAAAGCT 
GATCTTTCTG GAATGTCACC AACCAAGGGC CTATATTTAT CAAAAGCCAT CCACAAGTCA 
TACCTGGATG TCAGCGAAGA GGGCACGGAG GCAGCAGCAG CCACTGGGGA CAGCATCGCT 
GTAAAAAGCC TACCAATGAG AGCTCAGTTC AAGGCGAACC ACCCCTTCCT TTTCTTTATA 
AGGCACACTC ATACCAACAC GATCCTATTC TGTGGCAAGC TTGCCTCTCC CTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SERPINB11 ( NM_001291279.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001278208.1 Homo sapiens serpin family B member 11 (gene/pseudogene) (SERPINB11), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu14436
Clone ID Related Accession (Same CDS sequence)	NM_001291279.2 , NM_001291279.1
Accession Version	NM_001291279.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 654bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-06-29
Organism	Homo sapiens(human)
Product	serpin B11 isoform c
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC069356.6, DC383104.1, DC365081.1, AK296705.1 and AY739645.1. On Apr 1, 2014 this sequence version replaced XM_006722570.1. Transcript Variant: This variant (3) lacks an alternate exon and it thus differs in its 5' UTR and initiates translation at a downstream in-frame start codon, compared to variant 1. The encoded isoform (c) is shorter at the N-terminus, compared to isoform a. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: AK296705.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2144335, SAMEA2147975 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## polymorphic pseudogene :: PMID: 22393410 ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGTCCTGG TGAATGCCAT ATATTTCAAA GGACAATGGC AAAATAAATT TCAAGTAAGA 
GAGACAGTTA AAAGTCCTTT TCAGCTAAGT GAGGGTAAAA ATGTAACTGT GGAAATGATG 
TATCAAATTG GAACATTTAA ACTGGCCTTT GTAAAGGAGC CGCAGATGCA AGTTCTTGAG 
CTGCCCTACG TTAACAACAA ATTAAGCATG ATTATTCTGC TTCCAGTAGG CATAGCTAAT 
CTGAAACAGA TAGAAAAGCA GCTGAATTCG GGGACGTTTC ATGAGTGGAC AAGCTCTTCT 
AACATGATGG AAAGAGAAGT TGAAGTACAC CTCCCCCGAT TCAAACTTGA AACTAAGTAT 
GAGCTAAATT CCCTGTTAAA ATCTCTAGGG GTGACAGATC TCTTCAACCA GGTCAAAGCT 
GATCTTTCTG GAATGTCACC AACCAAGGGC CTATATTTAT CAAAAGCCAT CCACAAGTCA 
TACCTGGATG TCAGCGAAGA GGGCACGGAG GCAGCAGCAG CCACTGGGGA CAGCATCGCT 
GTAAAAAGCC TACCAATGAG AGCTCAGTTC AAGGCGAACC ACCCCTTCCT TTTCTTTATA 
AGGCACACTC ATACCAACAC GATCCTATTC TGTGGCAAGC TTGCCTCTCC CTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001278208.1
CDS	471..1124
Translation	MVLVNAIYFKGQWQNKFQVRETVKSPFQLSEGKNVTVEMMYQIGTFKLAFVKEPQMQVLELPYVNNKLSMIILLPVGIANLKQIEKQLNSGTFHEWTSSSNMMEREVEVHLPRFKLETKYELNSLLKSLGVTDLFNQVKADLSGMSPTKGLYLSKAIHKSYLDVSEEGTEAAAATGDSIAVKSLPMRAQFKANHPFLFFIRHTHTNTILFCGKLASP

Target ORF information:

RefSeq Version	NM_001291279.1
Organism	Homo sapiens(human)
Definition	Homo sapiens serpin family B member 11 (gene/pseudogene) (SERPINB11), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001291279.1

ORF Insert Sequence:

ATGGTCCTGG TGAATGCCAT ATATTTCAAA GGACAATGGC AAAATAAATT TCAAGTAAGA 
GAGACAGTTA AAAGTCCTTT TCAGCTAAGT GAGGGTAAAA ATGTAACTGT GGAAATGATG 
TATCAAATTG GAACATTTAA ACTGGCCTTT GTAAAGGAGC CGCAGATGCA AGTTCTTGAG 
CTGCCCTACG TTAACAACAA ATTAAGCATG ATTATTCTGC TTCCAGTAGG CATAGCTAAT 
CTGAAACAGA TAGAAAAGCA GCTGAATTCG GGGACGTTTC ATGAGTGGAC AAGCTCTTCT 
AACATGATGG AAAGAGAAGT TGAAGTACAC CTCCCCCGAT TCAAACTTGA AACTAAGTAT 
GAGCTAAATT CCCTGTTAAA ATCTCTAGGG GTGACAGATC TCTTCAACCA GGTCAAAGCT 
GATCTTTCTG GAATGTCACC AACCAAGGGC CTATATTTAT CAAAAGCCAT CCACAAGTCA 
TACCTGGATG TCAGCGAAGA GGGCACGGAG GCAGCAGCAG CCACTGGGGA CAGCATCGCT 
GTAAAAAGCC TACCAATGAG AGCTCAGTTC AAGGCGAACC ACCCCTTCCT TTTCTTTATA 
AGGCACACTC ATACCAACAC GATCCTATTC TGTGGCAAGC TTGCCTCTCC CTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SERPINB11 ( NM_001291278.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001278207.1 Homo sapiens serpin family B member 11 (gene/pseudogene) (SERPINB11), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu14434
Clone ID Related Accession (Same CDS sequence)	NM_001291278.2 , NM_001291278.1
Accession Version	NM_001291278.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 918bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-05-07
Organism	Homo sapiens(human)
Product	serpin B11 isoform b
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC069356.6 and KF459701.1. On May 8, 2019 this sequence version replaced NM_001291278.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## CDS exon combination :: AY792324.1 [ECO:0000331] RNAseq introns :: single sample supports all introns SAMEA1968832, SAMEA2144335 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## inferred exon combination :: based on alignments, homology polymorphic pseudogene :: PMID: 22393410 ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGGTTCTC TCAGCACAGC TAACGTTGAA TTTTGCCTTG ATGTGTTCAA AGAGCTGAAC 
AGTAACAACA TAGGAGATAA CATCTTCTTT TCTTCGCTGA GTCTGCTTTA TGCTCTAAGC 
ATGGTCCTCC TTGGTGCCAG GGGAGAGACT GAAGAGCAAT TGGAGAAGGT GCTTCATTTT 
AGTCATACTG TAGACTCATT AAAACCAGGG TTCAAGGACT CACCTAAGTG CAGCCAAGCT 
GGAAGAATTC ATTCCGAGTT TGGTGTCGAA TTCTCTCAAA TCAACCAGCC AGACTCTAAC 
TGTACCCTCA GCATTGCCAA CAGGCTCTAC GGGACAAAGA CGATGGCATT TCATCAGGGT 
AAAAATGTAA CTGTGGAAAT GATGTATCAA ATTGGAACAT TTAAACTGGC CTTTGTAAAG 
GAGCCGCAGA TGCAAGTTCT TGAGCTGCCC TACGTTAACA ACAAATTAAG CATGATTATT 
CTGCTTCCAG TAGGCATAGC TAATCTGAAA CAGATAGAAA AGCAGCTGAA TTCGGGGACG 
TTTCATGAGT GGACAAGCTC TTCTAACATG ATGGAAAGAG AAGTTGAAGT ACACCTCCCC 
CGATTCAAAC TTGAAACTAA GTATGAGCTA AATTCCCTGT TAAAATCTCT AGGGGTGACA 
GATCTCTTCA ACCAGGTCAA AGCTGATCTT TCTGGAATGT CACCAACCAA GGGCCTATAT 
TTATCAAAAG CCATCCACAA GTCATACCTG GATGTCAGCG AAGAGGGCAC GGAGGCAGCA 
GCAGCCACTG GGGACAGCAT CGCTGTAAAA AGCCTACCAA TGAGAGCTCA GTTCAAGGCG 
AACCACCCCT TCCTTTTCTT TATAAGGCAC ACTCATACCA ACACGATCCT ATTCTGTGGC 
AAGCTTGCCT CTCCCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001278207.1
CDS	63..980
Translation	MGSLSTANVEFCLDVFKELNSNNIGDNIFFSSLSLLYALSMVLLGARGETEEQLEKVLHFSHTVDSLKPGFKDSPKCSQAGRIHSEFGVEFSQINQPDSNCTLSIANRLYGTKTMAFHQGKNVTVEMMYQIGTFKLAFVKEPQMQVLELPYVNNKLSMIILLPVGIANLKQIEKQLNSGTFHEWTSSSNMMEREVEVHLPRFKLETKYELNSLLKSLGVTDLFNQVKADLSGMSPTKGLYLSKAIHKSYLDVSEEGTEAAAATGDSIAVKSLPMRAQFKANHPFLFFIRHTHTNTILFCGKLASP

Target ORF information:

RefSeq Version	NM_001291278.2
Organism	Homo sapiens(human)
Definition	Homo sapiens serpin family B member 11 (gene/pseudogene) (SERPINB11), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001291278.2

ORF Insert Sequence:

ATGGGTTCTC TCAGCACAGC TAACGTTGAA TTTTGCCTTG ATGTGTTCAA AGAGCTGAAC 
AGTAACAACA TAGGAGATAA CATCTTCTTT TCTTCGCTGA GTCTGCTTTA TGCTCTAAGC 
ATGGTCCTCC TTGGTGCCAG GGGAGAGACT GAAGAGCAAT TGGAGAAGGT GCTTCATTTT 
AGTCATACTG TAGACTCATT AAAACCAGGG TTCAAGGACT CACCTAAGTG CAGCCAAGCT 
GGAAGAATTC ATTCCGAGTT TGGTGTCGAA TTCTCTCAAA TCAACCAGCC AGACTCTAAC 
TGTACCCTCA GCATTGCCAA CAGGCTCTAC GGGACAAAGA CGATGGCATT TCATCAGGGT 
AAAAATGTAA CTGTGGAAAT GATGTATCAA ATTGGAACAT TTAAACTGGC CTTTGTAAAG 
GAGCCGCAGA TGCAAGTTCT TGAGCTGCCC TACGTTAACA ACAAATTAAG CATGATTATT 
CTGCTTCCAG TAGGCATAGC TAATCTGAAA CAGATAGAAA AGCAGCTGAA TTCGGGGACG 
TTTCATGAGT GGACAAGCTC TTCTAACATG ATGGAAAGAG AAGTTGAAGT ACACCTCCCC 
CGATTCAAAC TTGAAACTAA GTATGAGCTA AATTCCCTGT TAAAATCTCT AGGGGTGACA 
GATCTCTTCA ACCAGGTCAA AGCTGATCTT TCTGGAATGT CACCAACCAA GGGCCTATAT 
TTATCAAAAG CCATCCACAA GTCATACCTG GATGTCAGCG AAGAGGGCAC GGAGGCAGCA 
GCAGCCACTG GGGACAGCAT CGCTGTAAAA AGCCTACCAA TGAGAGCTCA GTTCAAGGCG 
AACCACCCCT TCCTTTTCTT TATAAGGCAC ACTCATACCA ACACGATCCT ATTCTGTGGC 
AAGCTTGCCT CTCCCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SERPINB11 ( NM_001291278.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001278207.1 Homo sapiens serpin family B member 11 (gene/pseudogene) (SERPINB11), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu14434
Clone ID Related Accession (Same CDS sequence)	NM_001291278.2 , NM_001291278.1
Accession Version	NM_001291278.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 918bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-06-29
Organism	Homo sapiens(human)
Product	serpin B11 isoform b
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC069356.6, DC383104.1, AY792324.1 and AY739645.1. On Apr 1, 2014 this sequence version replaced XM_006722569.1. Transcript Variant: This variant (2) differs in the 5' UTR and lacks two alternate exons that result in the loss of an in-frame segment in the central coding region, compared to variant 1. The encoded isoform (b) is shorter than isoform a. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## CDS exon combination :: AY792324.1 [ECO:0000331] RNAseq introns :: single sample supports all introns SAMEA1968832, SAMEA2144335 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## polymorphic pseudogene :: PMID: 22393410 ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGGTTCTC TCAGCACAGC TAACGTTGAA TTTTGCCTTG ATGTGTTCAA AGAGCTGAAC 
AGTAACAACA TAGGAGATAA CATCTTCTTT TCTTCGCTGA GTCTGCTTTA TGCTCTAAGC 
ATGGTCCTCC TTGGTGCCAG GGGAGAGACT GAAGAGCAAT TGGAGAAGGT GCTTCATTTT 
AGTCATACTG TAGACTCATT AAAACCAGGG TTCAAGGACT CACCTAAGTG CAGCCAAGCT 
GGAAGAATTC ATTCCGAGTT TGGTGTCGAA TTCTCTCAAA TCAACCAGCC AGACTCTAAC 
TGTACCCTCA GCATTGCCAA CAGGCTCTAC GGGACAAAGA CGATGGCATT TCATCAGGGT 
AAAAATGTAA CTGTGGAAAT GATGTATCAA ATTGGAACAT TTAAACTGGC CTTTGTAAAG 
GAGCCGCAGA TGCAAGTTCT TGAGCTGCCC TACGTTAACA ACAAATTAAG CATGATTATT 
CTGCTTCCAG TAGGCATAGC TAATCTGAAA CAGATAGAAA AGCAGCTGAA TTCGGGGACG 
TTTCATGAGT GGACAAGCTC TTCTAACATG ATGGAAAGAG AAGTTGAAGT ACACCTCCCC 
CGATTCAAAC TTGAAACTAA GTATGAGCTA AATTCCCTGT TAAAATCTCT AGGGGTGACA 
GATCTCTTCA ACCAGGTCAA AGCTGATCTT TCTGGAATGT CACCAACCAA GGGCCTATAT 
TTATCAAAAG CCATCCACAA GTCATACCTG GATGTCAGCG AAGAGGGCAC GGAGGCAGCA 
GCAGCCACTG GGGACAGCAT CGCTGTAAAA AGCCTACCAA TGAGAGCTCA GTTCAAGGCG 
AACCACCCCT TCCTTTTCTT TATAAGGCAC ACTCATACCA ACACGATCCT ATTCTGTGGC 
AAGCTTGCCT CTCCCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001278207.1
CDS	64..981
Translation	MGSLSTANVEFCLDVFKELNSNNIGDNIFFSSLSLLYALSMVLLGARGETEEQLEKVLHFSHTVDSLKPGFKDSPKCSQAGRIHSEFGVEFSQINQPDSNCTLSIANRLYGTKTMAFHQGKNVTVEMMYQIGTFKLAFVKEPQMQVLELPYVNNKLSMIILLPVGIANLKQIEKQLNSGTFHEWTSSSNMMEREVEVHLPRFKLETKYELNSLLKSLGVTDLFNQVKADLSGMSPTKGLYLSKAIHKSYLDVSEEGTEAAAATGDSIAVKSLPMRAQFKANHPFLFFIRHTHTNTILFCGKLASP

Target ORF information:

RefSeq Version	NM_001291278.1
Organism	Homo sapiens(human)
Definition	Homo sapiens serpin family B member 11 (gene/pseudogene) (SERPINB11), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001291278.1

ORF Insert Sequence:

ATGGGTTCTC TCAGCACAGC TAACGTTGAA TTTTGCCTTG ATGTGTTCAA AGAGCTGAAC 
AGTAACAACA TAGGAGATAA CATCTTCTTT TCTTCGCTGA GTCTGCTTTA TGCTCTAAGC 
ATGGTCCTCC TTGGTGCCAG GGGAGAGACT GAAGAGCAAT TGGAGAAGGT GCTTCATTTT 
AGTCATACTG TAGACTCATT AAAACCAGGG TTCAAGGACT CACCTAAGTG CAGCCAAGCT 
GGAAGAATTC ATTCCGAGTT TGGTGTCGAA TTCTCTCAAA TCAACCAGCC AGACTCTAAC 
TGTACCCTCA GCATTGCCAA CAGGCTCTAC GGGACAAAGA CGATGGCATT TCATCAGGGT 
AAAAATGTAA CTGTGGAAAT GATGTATCAA ATTGGAACAT TTAAACTGGC CTTTGTAAAG 
GAGCCGCAGA TGCAAGTTCT TGAGCTGCCC TACGTTAACA ACAAATTAAG CATGATTATT 
CTGCTTCCAG TAGGCATAGC TAATCTGAAA CAGATAGAAA AGCAGCTGAA TTCGGGGACG 
TTTCATGAGT GGACAAGCTC TTCTAACATG ATGGAAAGAG AAGTTGAAGT ACACCTCCCC 
CGATTCAAAC TTGAAACTAA GTATGAGCTA AATTCCCTGT TAAAATCTCT AGGGGTGACA 
GATCTCTTCA ACCAGGTCAA AGCTGATCTT TCTGGAATGT CACCAACCAA GGGCCTATAT 
TTATCAAAAG CCATCCACAA GTCATACCTG GATGTCAGCG AAGAGGGCAC GGAGGCAGCA 
GCAGCCACTG GGGACAGCAT CGCTGTAAAA AGCCTACCAA TGAGAGCTCA GTTCAAGGCG 
AACCACCCCT TCCTTTTCTT TATAAGGCAC ACTCATACCA ACACGATCCT ATTCTGTGGC 
AAGCTTGCCT CTCCCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Update of the human and mouse SERPIN gene superfamily.
Human genomics722(2013 Oct)
Heit C,Jackson BC,McAndrews M,Wright MW,Thompson DC,Silverman GA,Nebert DW,Vasiliou V

Avian SERPINB11 gene: a marker for ovarian endometrioid cancer in chickens.
Experimental biology and medicine (Maywood, N.J.)237(2)150-9(2012 Feb)
Lim W,Kim JH,Ahn SE,Jeong W,Kim J,Bazer FW,Han JY,Song G

Loss and gain of function in SERPINB11: an example of a gene under selection on standing variation, with implications for host-pathogen interactions.
PloS one7(2)e32518(2012)
Seixas S,Ivanova N,Ferreira Z,Rocha J,Victor BL

SERPINB11 is a new noninhibitory intracellular serpin. Common single nucleotide polymorphisms in the scaffold impair conformational change.
The Journal of biological chemistry282(34)24948-60(2007 Aug)
Askew DJ,Cataltepe S,Kumar V,Edwards C,Pace SM,Howarth RN,Pak SC,Askew YS,Br?mme D,Luke CJ,Whisstock JC,Silverman GA

Prominent use of distal 5' transcription start sites and discovery of a large number of additional exons in ENCODE regions.
Genome research17(6)746-59(2007 Jun)
Denoeud F,Kapranov P,Ucla C,Frankish A,Castelo R,Drenkow J,Lagarde J,Alioto T,Manzano C,Chrast J,Dike S,Wyss C,Henrichsen CN,Holroyd N,Dickson MC,Taylor R,Hance Z,Foissac S,Myers RM,Rogers J,Hubbard T,Harrow J,Guig? R,Gingeras TR,Antonarakis SE,Reymond A

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SERPINB11 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

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