Gene Symbol | KYNU |
Entrez Gene ID | 8942 |
Full Name | kynureninase |
Synonyms | KYNUU,VCRL2 |
General protein information |
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Gene Type | protein-coding |
Organism | Homo sapiens(Human) |
Genome | |
Summary | Kynureninase is a pyridoxal-5'-phosphate (pyridoxal-P) dependent enzyme that catalyzes the cleavage of L-kynurenine and L-3-hydroxykynurenine into anthranilic and 3-hydroxyanthranilic acids, respectively. Kynureninase is involved in the biosynthesis of NAD cofactors from tryptophan through the kynurenine pathway. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2010]. |
Disorder MIM: | |
Disorder Html: | ?Hydroxykynureninuria, 236800 (3); Vertebral, cardiac, renal, and limb defects syndrome 2, 617661 (3) |