PROZ cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	PROZ
Entrez Gene ID	8858
Full Name	protein Z, vitamin K dependent plasma glycoprotein
Synonyms	PZ
General protein information	Preferred Names protein Z, vitamin K dependent plasma glycoprotein Names vitamin K-dependent protein Z vitamin K-dependent protein Z precursor variant 1
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 13 Map Location: 13q34
Summary	This gene encodes a liver vitamin K-dependent glycoprotein that is synthesized in the liver and secreted into the plasma. The encoded protein plays a role in regulating blood coagulation by complexing with protein Z-dependent protease inhibitor to directly inhibit activated factor X at the phospholipid surface. Deficiencies in this protein are associated with an increased risk of ischemic arterial diseases and fetal loss. Mutations in this gene are the cause of protein Z deficiency. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2012].
Disorder MIM:	176895
Disorder Html:	[Protein Z deficiency], 614024 (3)

mRNA and Protein(s)

mRNA	Protein	Name
XM_017020813.1	XP_016876302.1	vitamin K-dependent protein Z isoform X2
NM_003891.3	NP_003882.1	vitamin K-dependent protein Z isoform 2 precursor
NM_003891.2	NP_003882.1	vitamin K-dependent protein Z isoform 2 precursor
XM_017020812.1	XP_016876301.1	vitamin K-dependent protein Z isoform X1
NM_001256134.1	NP_001243063.1	vitamin K-dependent protein Z isoform 1 precursor

Pathways from BioSystems

Homologies

Mus musculus (house mouse)	Proz	NP_080110.1
Gallus gallus (chicken)	PROZ	XP_416945.3
Rattus norvegicus (Norway rat)	Proz	XP_006253535.1
Homo sapiens (human)	PROZ	NP_003882.1
Pan troglodytes (chimpanzee)	PROZ	XP_522739.3
	PROZ	XP_001087442.1
Xenopus tropicalis (tropical clawed frog)	proz	NP_001116189.1
Bos taurus (cattle)	PROZ	XP_002692060.3

Gene Ontology
Bibliography

Related articles in PubMed

Low plasma protein Z levels are associated with an increased risk for perioperative bleedings.
Hinterleitner C, Kreisselmeier KP, Pecher AC, Mauz PS, Kanz L, Kopp HG, Jaschonek KG
European journal of haematology(2018 Jan)

The Role of Protein Z and Protein Z-Dependent Protease Inhibitor Polymorphisms in the Development of Prosthetic Heart Valve Thrombosis.
Karakoyun S, Ozan G?rsoy M, Kal??k M, Yesin M, G?nd?z S, Ali Astarc?o?lu M, Bayram Z, ?akal B, Bayam E, ?zkan M
The Journal of heart valve disease26(4)460-466(2017 Jul)

The gene for human protein Z is localized to chromosome 13 at band q34 and is coded by eight regular exons and one alternative exon.
Fujimaki K, Yamazaki T, Taniwaki M, Ichinose A
Biochemistry37(19)6838-46(1998 May)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Data suggest oxidized lipid vesicles with phosphatidylserine/polyunsaturated fatty acids promote inactivation of ZPI-PZ complex or free ZPI; binding of PZ-complexed or free ZPI to oxidized vesicles mediates inactivation of ZPI (an inhibitor of FXa); blocking heparin- (anticoagulant-)binding site on ZPI interferes with binding to lipid or PZ. (ZPI = protein Z-dependent protease inhibitor; PZ = protein Z; FXa = factor Xa)
Title: Lipid oxidation inactivates the anticoagulant function of protein Z-dependent protease inhibitor (ZPI).

SAA, PROZ, and C4BPB may serve as new potential biomarkers for TB
Title: Serum amyloid A, protein Z, and C4b-binding protein ? chain as new potential biomarkers for pulmonary tuberculosis.

Protein Z is a plasma protein involving blood coagulation and inflammation. Low protein Z was found to be associated significantly with acute my.ocardial infarction in coronary atherosclerosis disease patients
Title: Low protein Z plasma level is a risk factor for acute myocardial infarction in coronary atherosclerosis disease patients.

Protein Z G79A AG/AA polymorphism may be a risk factor for thrombosis in systemic lupus erythematosus Egyptian patients.
Title: Contribution of protein Z gene single-nucleotide polymorphism to systemic lupus erythematosus in Egyptian patients.

Family-based association study revealed that the G allele of Protein Z rs2273971, and haplotypes GA, CG, and CGA of Protein Z and factor VII had a significant effect on cerebral hemorrhage susceptibility.
Title: Association of protein Z and factor VII gene polymorphisms with risk of cerebral hemorrhage: a case-control and a family-based association study in a Chinese Han population.

The following PROZ gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the PROZ cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu15828	NM_003891.2 Latest version!	Homo sapiens protein Z, vitamin K dependent plasma glycoprotein (PROZ), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
OHu20282	NM_001256134.1 Latest version!	Homo sapiens protein Z, vitamin K dependent plasma glycoprotein (PROZ), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
OHu108667	NM_003891.3 Latest version!	Homo sapiens protein Z, vitamin K dependent plasma glycoprotein (PROZ), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
OHu84671	XM_017020812.1 Latest version!	Homo sapiens protein Z, vitamin K dependent plasma glycoprotein (PROZ), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
OHu84672	XM_017020813.1 Latest version!	Homo sapiens protein Z, vitamin K dependent plasma glycoprotein (PROZ), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

PROZ ( NM_003891.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_003882.1 Homo sapiens protein Z, vitamin K dependent plasma glycoprotein (PROZ), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu15828
Clone ID Related Accession (Same CDS sequence)	NM_003891.2
Accession Version	NM_003891.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1203bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-22
Organism	Homo sapiens(human)
Product	vitamin K-dependent protein Z isoform 2 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from M55670.1, BC074906.2 and AI492996.1. On Jan 7, 2012 this sequence version replaced NM_003891.1. Transcript Variant: This variant (2) lacks an in-frame exon in the coding region, compared to variant 1. The encoded isoform (2) is shorter, compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: M55670.1, BC074906.2 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1970526, SAMEA2145122 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCAGGCT GCGTCCCACT GCTCCAGGGC CTGGTCCTGG TCCTCGCCCT CCATCGTGTG 
GAGCCCTCAG TATTTCTCCC GGCCTCCAAA GCAAACGACG TTCTGGTGAG GTGGAAGCGT 
GCGGGCTCCT ATCTTCTGGA AGAACTCTTC GAGGGAAACT TGGAAAAAGA ATGTTATGAA 
GAAATCTGTG TCTATGAAGA AGCAAGAGAA GTGTTTGAAA ATGAAGTAGT CACTGATGAA 
TTCTGGAGAC GATATAAGGG CGGCTCCCCG TGCATCTCCC AGCCCTGCCT CCACAACGGC 
TCTTGCCAGG ACAGCATCTG GGGCTACACC TGCACCTGCT CCCCCGGCTA TGAGGGCAGC 
AACTGCGAGC TGGCTAAAAA TGAATGTCAC CCAGAGCGGA CTGATGGGTG TCAACACTTC 
TGCCTCCCAG GACAGGAATC CTACACGTGC AGCTGTGCTC AGGGCTACAG GCTTGGTGAG 
GACCACAAAC AGTGTGTGCC CCACGACCAG TGTGCCTGCG GGGTGCTGAC CTCTGAGAAG 
CGTGCACCGG ATCTACAGGA CCTCCCGTGG CAGGTAAAGT TAACAAATTC CGAAGGAAAA 
GACTTCTGTG GTGGTGTTAT AATACGGGAA AATTTTGTAC TGACAACAGC AAAATGTTCA 
CTGTTACACA GGAATATTAC TGTAAAAACA TATTTTAACA GAACGAGCCA AGACCCGCTG 
ATGATCAAGA TAACGCACGT CCATGTGCAC ATGCGGTATG ACGCGGACGC GGGGGAGAAT 
GACCTGTCAC TGCTGGAGCT GGAGTGGCCC ATCCAGTGCC CAGGTGCGGG GCTCCCCGTG 
TGCACCCCTG AGAAAGACTT CGCTGAGCAC CTCCTCATCC CACGCACCAG GGGCCTCCTC 
AGCGGCTGGG CACGCAATGG CACTGACCTG GGCAACTCGC TGACCACGCG GCCTGTCACA 
CTTGTGGAGG GGGAGGAGTG CGGGCAGGTC CTGAATGTGA CTGTCACCAC CAGGACCTAC 
TGTGAGAGAA GCAGCGTGGC GGCCATGCAC TGGATGGATG GAAGTGTGGT CACCAGAGAA 
CACAGAGGCT CCTGGTTTCT CACGGGGGTC CTGGGCTCGC AGCCAGTAGG AGGGCAGGCT 
CACATGGTCC TTGTCACCAA GGTCTCCAGG TACTCACTCT GGTTTAAACA GATCATGAAC 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_003882.1
CDS	8..1210
Translation	MAGCVPLLQGLVLVLALHRVEPSVFLPASKANDVLVRWKRAGSYLLEELFEGNLEKECYEEICVYEEAREVFENEVVTDEFWRRYKGGSPCISQPCLHNGSCQDSIWGYTCTCSPGYEGSNCELAKNECHPERTDGCQHFCLPGQESYTCSCAQGYRLGEDHKQCVPHDQCACGVLTSEKRAPDLQDLPWQVKLTNSEGKDFCGGVIIRENFVLTTAKCSLLHRNITVKTYFNRTSQDPLMIKITHVHVHMRYDADAGENDLSLLELEWPIQCPGAGLPVCTPEKDFAEHLLIPRTRGLLSGWARNGTDLGNSLTTRPVTLVEGEECGQVLNVTVTTRTYCERSSVAAMHWMDGSVVTREHRGSWFLTGVLGSQPVGGQAHMVLVTKVSRYSLWFKQIMN

Target ORF information:

RefSeq Version	NM_003891.2
Organism	Homo sapiens(human)
Definition	Homo sapiens protein Z, vitamin K dependent plasma glycoprotein (PROZ), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_003891.2

ORF Insert Sequence:

ATGGCAGGCT GCGTCCCACT GCTCCAGGGC CTGGTCCTGG TCCTCGCCCT CCATCGTGTG 
GAGCCCTCAG TATTTCTCCC GGCCTCCAAA GCAAACGACG TTCTGGTGAG GTGGAAGCGT 
GCGGGCTCCT ATCTTCTGGA AGAACTCTTC GAGGGAAACT TGGAAAAAGA ATGTTATGAA 
GAAATCTGTG TCTATGAAGA AGCAAGAGAA GTGTTTGAAA ATGAAGTAGT CACTGATGAA 
TTCTGGAGAC GATATAAGGG CGGCTCCCCG TGCATCTCCC AGCCCTGCCT CCACAACGGC 
TCTTGCCAGG ACAGCATCTG GGGCTACACC TGCACCTGCT CCCCCGGCTA TGAGGGCAGC 
AACTGCGAGC TGGCTAAAAA TGAATGTCAC CCAGAGCGGA CTGATGGGTG TCAACACTTC 
TGCCTCCCAG GACAGGAATC CTACACGTGC AGCTGTGCTC AGGGCTACAG GCTTGGTGAG 
GACCACAAAC AGTGTGTGCC CCACGACCAG TGTGCCTGCG GGGTGCTGAC CTCTGAGAAG 
CGTGCACCGG ATCTACAGGA CCTCCCGTGG CAGGTAAAGT TAACAAATTC CGAAGGAAAA 
GACTTCTGTG GTGGTGTTAT AATACGGGAA AATTTTGTAC TGACAACAGC AAAATGTTCA 
CTGTTACACA GGAATATTAC TGTAAAAACA TATTTTAACA GAACGAGCCA AGACCCGCTG 
ATGATCAAGA TAACGCACGT CCATGTGCAC ATGCGGTATG ACGCGGACGC GGGGGAGAAT 
GACCTGTCAC TGCTGGAGCT GGAGTGGCCC ATCCAGTGCC CAGGTGCGGG GCTCCCCGTG 
TGCACCCCTG AGAAAGACTT CGCTGAGCAC CTCCTCATCC CACGCACCAG GGGCCTCCTC 
AGCGGCTGGG CACGCAATGG CACTGACCTG GGCAACTCGC TGACCACGCG GCCTGTCACA 
CTTGTGGAGG GGGAGGAGTG CGGGCAGGTC CTGAATGTGA CTGTCACCAC CAGGACCTAC 
TGTGAGAGAA GCAGCGTGGC GGCCATGCAC TGGATGGATG GAAGTGTGGT CACCAGAGAA 
CACAGAGGCT CCTGGTTTCT CACGGGGGTC CTGGGCTCGC AGCCAGTAGG AGGGCAGGCT 
CACATGGTCC TTGTCACCAA GGTCTCCAGG TACTCACTCT GGTTTAAACA GATCATGAAC 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PROZ ( NM_001256134.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001243063.1 Homo sapiens protein Z, vitamin K dependent plasma glycoprotein (PROZ), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu20282
Clone ID Related Accession (Same CDS sequence)	NM_001256134.1
Accession Version	NM_001256134.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1269bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-23
Organism	Homo sapiens(human)
Product	vitamin K-dependent protein Z isoform 1 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from M55671.1 and AI492996.1. This sequence is a reference standard in the RefSeqGene project. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: M55671.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2145122, SAMEA2155590 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCAGGCT GCGTCCCACT GCTCCAGGGC CTGGTCCTGG TCCTCGCCCT CCATCGTGTG 
GAGCCCTCAG CCACTTCACT GAAGGAACGA CATGGACTCC ATTCTGACTC TGCCTGCACA 
GGCGTCCAGG AAAGCTTATT TCTCCCGGCC TCCAAAGCAA ACGACGTTCT GGTGAGGTGG 
AAGCGTGCGG GCTCCTATCT TCTGGAAGAA CTCTTCGAGG GAAACTTGGA AAAAGAATGT 
TATGAAGAAA TCTGTGTCTA TGAAGAAGCA AGAGAAGTGT TTGAAAATGA AGTAGTCACT 
GATGAATTCT GGAGACGATA TAAGGGCGGC TCCCCGTGCA TCTCCCAGCC CTGCCTCCAC 
AACGGCTCTT GCCAGGACAG CATCTGGGGC TACACCTGCA CCTGCTCCCC CGGCTATGAG 
GGCAGCAACT GCGAGCTGGC TAAAAATGAA TGTCACCCAG AGCGGACTGA TGGGTGTCAA 
CACTTCTGCC TCCCAGGACA GGAATCCTAC ACGTGCAGCT GTGCTCAGGG CTACAGGCTT 
GGTGAGGACC ACAAACAGTG TGTGCCCCAC GACCAGTGTG CCTGCGGGGT GCTGACCTCT 
GAGAAGCGTG CACCGGATCT ACAGGACCTC CCGTGGCAGG TAAAGTTAAC AAATTCCGAA 
GGAAAAGACT TCTGTGGTGG TGTTATAATA CGGGAAAATT TTGTACTGAC AACAGCAAAA 
TGTTCACTGT TACACAGGAA TATTACTGTA AAAACATATT TTAACAGAAC GAGCCAAGAC 
CCGCTGATGA TCAAGATAAC GCACGTCCAT GTGCACATGC GGTATGACGC GGACGCGGGG 
GAGAATGACC TGTCACTGCT GGAGCTGGAG TGGCCCATCC AGTGCCCAGG TGCGGGGCTC 
CCCGTGTGCA CCCCTGAGAA AGACTTCGCT GAGCACCTCC TCATCCCACG CACCAGGGGC 
CTCCTCAGCG GCTGGGCACG CAATGGCACT GACCTGGGCA ACTCGCTGAC CACGCGGCCT 
GTCACACTTG TGGAGGGGGA GGAGTGCGGG CAGGTCCTGA ATGTGACTGT CACCACCAGG 
ACCTACTGTG AGAGAAGCAG CGTGGCGGCC ATGCACTGGA TGGATGGAAG TGTGGTCACC 
AGAGAACACA GAGGCTCCTG GTTTCTCACG GGGGTCCTGG GCTCGCAGCC AGTAGGAGGG 
CAGGCTCACA TGGTCCTTGT CACCAAGGTC TCCAGGTACT CACTCTGGTT TAAACAGATC 
ATGAACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001243063.1
CDS	8..1276
Translation	MAGCVPLLQGLVLVLALHRVEPSATSLKERHGLHSDSACTGVQESLFLPASKANDVLVRWKRAGSYLLEELFEGNLEKECYEEICVYEEAREVFENEVVTDEFWRRYKGGSPCISQPCLHNGSCQDSIWGYTCTCSPGYEGSNCELAKNECHPERTDGCQHFCLPGQESYTCSCAQGYRLGEDHKQCVPHDQCACGVLTSEKRAPDLQDLPWQVKLTNSEGKDFCGGVIIRENFVLTTAKCSLLHRNITVKTYFNRTSQDPLMIKITHVHVHMRYDADAGENDLSLLELEWPIQCPGAGLPVCTPEKDFAEHLLIPRTRGLLSGWARNGTDLGNSLTTRPVTLVEGEECGQVLNVTVTTRTYCERSSVAAMHWMDGSVVTREHRGSWFLTGVLGSQPVGGQAHMVLVTKVSRYSLWFKQIMN

Target ORF information:

RefSeq Version	NM_001256134.1
Organism	Homo sapiens(human)
Definition	Homo sapiens protein Z, vitamin K dependent plasma glycoprotein (PROZ), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001256134.1

ORF Insert Sequence:

ATGGCAGGCT GCGTCCCACT GCTCCAGGGC CTGGTCCTGG TCCTCGCCCT CCATCGTGTG 
GAGCCCTCAG CCACTTCACT GAAGGAACGA CATGGACTCC ATTCTGACTC TGCCTGCACA 
GGCGTCCAGG AAAGCTTATT TCTCCCGGCC TCCAAAGCAA ACGACGTTCT GGTGAGGTGG 
AAGCGTGCGG GCTCCTATCT TCTGGAAGAA CTCTTCGAGG GAAACTTGGA AAAAGAATGT 
TATGAAGAAA TCTGTGTCTA TGAAGAAGCA AGAGAAGTGT TTGAAAATGA AGTAGTCACT 
GATGAATTCT GGAGACGATA TAAGGGCGGC TCCCCGTGCA TCTCCCAGCC CTGCCTCCAC 
AACGGCTCTT GCCAGGACAG CATCTGGGGC TACACCTGCA CCTGCTCCCC CGGCTATGAG 
GGCAGCAACT GCGAGCTGGC TAAAAATGAA TGTCACCCAG AGCGGACTGA TGGGTGTCAA 
CACTTCTGCC TCCCAGGACA GGAATCCTAC ACGTGCAGCT GTGCTCAGGG CTACAGGCTT 
GGTGAGGACC ACAAACAGTG TGTGCCCCAC GACCAGTGTG CCTGCGGGGT GCTGACCTCT 
GAGAAGCGTG CACCGGATCT ACAGGACCTC CCGTGGCAGG TAAAGTTAAC AAATTCCGAA 
GGAAAAGACT TCTGTGGTGG TGTTATAATA CGGGAAAATT TTGTACTGAC AACAGCAAAA 
TGTTCACTGT TACACAGGAA TATTACTGTA AAAACATATT TTAACAGAAC GAGCCAAGAC 
CCGCTGATGA TCAAGATAAC GCACGTCCAT GTGCACATGC GGTATGACGC GGACGCGGGG 
GAGAATGACC TGTCACTGCT GGAGCTGGAG TGGCCCATCC AGTGCCCAGG TGCGGGGCTC 
CCCGTGTGCA CCCCTGAGAA AGACTTCGCT GAGCACCTCC TCATCCCACG CACCAGGGGC 
CTCCTCAGCG GCTGGGCACG CAATGGCACT GACCTGGGCA ACTCGCTGAC CACGCGGCCT 
GTCACACTTG TGGAGGGGGA GGAGTGCGGG CAGGTCCTGA ATGTGACTGT CACCACCAGG 
ACCTACTGTG AGAGAAGCAG CGTGGCGGCC ATGCACTGGA TGGATGGAAG TGTGGTCACC 
AGAGAACACA GAGGCTCCTG GTTTCTCACG GGGGTCCTGG GCTCGCAGCC AGTAGGAGGG 
CAGGCTCACA TGGTCCTTGT CACCAAGGTC TCCAGGTACT CACTCTGGTT TAAACAGATC 
ATGAACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PROZ ( NM_003891.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_003882.1 Homo sapiens protein Z, vitamin K dependent plasma glycoprotein (PROZ), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu108667
Clone ID Related Accession (Same CDS sequence)	NM_003891.3
Accession Version	NM_003891.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1203bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-28
Organism	Homo sapiens(human)
Product	vitamin K-dependent protein Z isoform 2 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AL137002.19. On Jun 2, 2019 this sequence version replaced NM_003891.2. Transcript Variant: This variant (2) lacks an in-frame exon in the coding region, compared to variant 1. The encoded isoform (2) is shorter, compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR5189664.152222.1, M55670.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1970526, SAMEA2145122 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on manual assertion, conservation, expression ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGCAGGCT GCGTCCCACT GCTCCAGGGC CTGGTCCTGG TCCTCGCCCT CCATCGTGTG 
GAGCCCTCAG TATTTCTCCC GGCCTCCAAA GCAAACGACG TTCTGGTGAG GTGGAAGCGT 
GCGGGCTCCT ATCTTCTGGA AGAACTCTTC GAGGGAAACT TGGAAAAAGA ATGTTATGAA 
GAAATCTGTG TCTATGAAGA AGCAAGAGAA GTGTTTGAAA ATGAAGTAGT CACTGATGAA 
TTCTGGAGAC GATATAAGGG CGGCTCCCCG TGCATCTCCC AGCCCTGCCT CCACAACGGC 
TCTTGCCAGG ACAGCATCTG GGGCTACACC TGCACCTGCT CCCCCGGCTA TGAGGGCAGC 
AACTGCGAGC TGGCTAAAAA TGAATGTCAC CCAGAGCGGA CTGATGGGTG TCAACACTTC 
TGCCTCCCAG GACAGGAATC CTACACATGC AGCTGTGCTC AGGGCTACAG GCTTGGTGAG 
GACCACAAAC AGTGTGTGCC CCACGACCAG TGTGCCTGCG GGGTGCTGAC CTCTGAGAAG 
CGTGCACCGG ATCTACAGGA CCTCCCGTGG CAGGTAAAGT TAACAAATTC CGAAGGAAAA 
GACTTCTGTG GTGGTGTTAT AATACGGGAA AATTTTGTAC TGACAACAGC AAAATGTTCA 
CTGTTACACA GGAATATTAC TGTAAAAACA TATTTTAACA GAACGAGCCA AGACCCGCTG 
ATGATCAAGA TAACGCACGT CCATGTGCAC ATGCGGTATG ACGCGGACGC GGGGGAGAAT 
GACCTGTCAC TGCTGGAGCT GGAGTGGCCC ATCCAGTGCC CAGGTGCGGG GCTCCCCGTG 
TGCACCCCTG AGAAAGACTT CGCTGAGCAC CTCCTCATCC CACGCACCAG GGGCCTCCTC 
AGCGGCTGGG CACGCAATGG CACTGACCTG GGCAACTCGC TGACCACGCG GCCTGTCACA 
CTTGTGGAGG GGGAGGAGTG CGGGCAGGTC CTGAATGTGA CTGTCACCAC CAGGACCTAC 
TGTGAGAGAA GCAGCGTGGC GGCCATGCAC TGGATGGATG GAAGTGTGGT CACCAGAGAA 
CACAGAGGCT CCTGGTTTCT CACGGGGGTC CTGGGCTCGC AGCCAGTAGG AGGGCAGGCT 
CACATGGTCC TTGTCACCAA GGTCTCCAGG TACTCACTCT GGTTTAAACA GATCATGAAC 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_003882.1
CDS	14..1216
Translation	MAGCVPLLQGLVLVLALHRVEPSVFLPASKANDVLVRWKRAGSYLLEELFEGNLEKECYEEICVYEEAREVFENEVVTDEFWRRYKGGSPCISQPCLHNGSCQDSIWGYTCTCSPGYEGSNCELAKNECHPERTDGCQHFCLPGQESYTCSCAQGYRLGEDHKQCVPHDQCACGVLTSEKRAPDLQDLPWQVKLTNSEGKDFCGGVIIRENFVLTTAKCSLLHRNITVKTYFNRTSQDPLMIKITHVHVHMRYDADAGENDLSLLELEWPIQCPGAGLPVCTPEKDFAEHLLIPRTRGLLSGWARNGTDLGNSLTTRPVTLVEGEECGQVLNVTVTTRTYCERSSVAAMHWMDGSVVTREHRGSWFLTGVLGSQPVGGQAHMVLVTKVSRYSLWFKQIMN

Target ORF information:

RefSeq Version	NM_003891.3
Organism	Homo sapiens(human)
Definition	Homo sapiens protein Z, vitamin K dependent plasma glycoprotein (PROZ), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_003891.3

ORF Insert Sequence:

ATGGCAGGCT GCGTCCCACT GCTCCAGGGC CTGGTCCTGG TCCTCGCCCT CCATCGTGTG 
GAGCCCTCAG TATTTCTCCC GGCCTCCAAA GCAAACGACG TTCTGGTGAG GTGGAAGCGT 
GCGGGCTCCT ATCTTCTGGA AGAACTCTTC GAGGGAAACT TGGAAAAAGA ATGTTATGAA 
GAAATCTGTG TCTATGAAGA AGCAAGAGAA GTGTTTGAAA ATGAAGTAGT CACTGATGAA 
TTCTGGAGAC GATATAAGGG CGGCTCCCCG TGCATCTCCC AGCCCTGCCT CCACAACGGC 
TCTTGCCAGG ACAGCATCTG GGGCTACACC TGCACCTGCT CCCCCGGCTA TGAGGGCAGC 
AACTGCGAGC TGGCTAAAAA TGAATGTCAC CCAGAGCGGA CTGATGGGTG TCAACACTTC 
TGCCTCCCAG GACAGGAATC CTACACATGC AGCTGTGCTC AGGGCTACAG GCTTGGTGAG 
GACCACAAAC AGTGTGTGCC CCACGACCAG TGTGCCTGCG GGGTGCTGAC CTCTGAGAAG 
CGTGCACCGG ATCTACAGGA CCTCCCGTGG CAGGTAAAGT TAACAAATTC CGAAGGAAAA 
GACTTCTGTG GTGGTGTTAT AATACGGGAA AATTTTGTAC TGACAACAGC AAAATGTTCA 
CTGTTACACA GGAATATTAC TGTAAAAACA TATTTTAACA GAACGAGCCA AGACCCGCTG 
ATGATCAAGA TAACGCACGT CCATGTGCAC ATGCGGTATG ACGCGGACGC GGGGGAGAAT 
GACCTGTCAC TGCTGGAGCT GGAGTGGCCC ATCCAGTGCC CAGGTGCGGG GCTCCCCGTG 
TGCACCCCTG AGAAAGACTT CGCTGAGCAC CTCCTCATCC CACGCACCAG GGGCCTCCTC 
AGCGGCTGGG CACGCAATGG CACTGACCTG GGCAACTCGC TGACCACGCG GCCTGTCACA 
CTTGTGGAGG GGGAGGAGTG CGGGCAGGTC CTGAATGTGA CTGTCACCAC CAGGACCTAC 
TGTGAGAGAA GCAGCGTGGC GGCCATGCAC TGGATGGATG GAAGTGTGGT CACCAGAGAA 
CACAGAGGCT CCTGGTTTCT CACGGGGGTC CTGGGCTCGC AGCCAGTAGG AGGGCAGGCT 
CACATGGTCC TTGTCACCAA GGTCTCCAGG TACTCACTCT GGTTTAAACA GATCATGAAC 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PROZ ( XM_017020812.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016876301.1 Homo sapiens protein Z, vitamin K dependent plasma glycoprotein (PROZ), transcript variant X1, mRNA.

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CloneID	OHu84671
Clone ID Related Accession (Same CDS sequence)	XM_017020812.1
Accession Version	XM_017020812.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1404bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	vitamin K-dependent protein Z isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000013.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAGTAGAA CGAGAAAACG TCAGGAGGGA AGCACACAGC TGCACAGGTC GTGCCCCGAG 
GCTCCTGCTG CCGGCACCTC CCCCAGCCTG GACTTTGGCT GTGTTTGTAG CCCTGTCCCA 
GCGCTCCGGG TGGGAATGGC AGGCTGCGTC CCACTGCTCC AGGGCCTGGT CCTGGTCCTC 
GCCCTCCATC GTGTGGAGCC CTCAGCCACT TCACTGAAGG AACGACATGG ACTCCATTCT 
GACTCTGCCT GCACAGGCGT CCAGGAAAGC TTATTTCTCC CGGCCTCCAA AGCAAACGAC 
GTTCTGGTGA GGTGGAAGCG TGCGGGCTCC TATCTTCTGG AAGAACTCTT CGAGGGAAAC 
TTGGAAAAAG AATGTTATGA AGAAATCTGT GTCTATGAAG AAGCAAGAGA AGTGTTTGAA 
AATGAAGTAG TCACTGATGA ATTCTGGAGA CGATATAAGG GCGGCTCCCC GTGCATCTCC 
CAGCCCTGCC TCCACAACGG CTCTTGCCAG GACAGCATCT GGGGCTACAC CTGCACCTGC 
TCCCCCGGCT ATGAGGGCAG CAACTGCGAG CTGGCTAAAA ATGAATGTCA CCCAGAGCGG 
ACTGATGGGT GTCAACACTT CTGCCTCCCA GGACAGGAAT CCTACACATG CAGCTGTGCT 
CAGGGCTACA GGCTTGGTGA GGACCACAAA CAGTGTGTGC CCCACGACCA GTGTGCCTGC 
GGGGTGCTGA CCTCTGAGAA GCGTGCACCG GATCTACAGG ACCTCCCGTG GCAGGTAAAG 
TTAACAAATT CCGAAGGAAA AGACTTCTGT GGTGGTGTTA TAATACGGGA AAATTTTGTA 
CTGACAACAG CAAAATGTTC ACTGTTACAC AGGAATATTA CTGTAAAAAC ATATTTTAAC 
AGAACGAGCC AAGACCCGCT GATGATCAAG ATAACGCACG TCCATGTGCA CATGCGGTAT 
GACGCGGACG CGGGGGAGAA TGACCTGTCA CTGCTGGAGC TGGAGTGGCC CATCCAGTGC 
CCAGGTGCGG GGCTCCCCGT GTGCACCCCT GAGAAAGACT TCGCTGAGCA CCTCCTCATC 
CCACGCACCA GGGGCCTCCT CAGCGGCTGG GCACGCAATG GCACTGACCT GGGCAACTCG 
CTGACCACGC GGCCTGTCAC ACTTGTGGAG GGGGAGGAGT GCGGGCAGGT CCTGAATGTG 
ACTGTCACCA CCAGGACCTA CTGTGAGAGA AGCAGCGTGG CGGCCATGCA CTGGATGGAT 
GGAAGTGTGG TCACCAGAGA ACACAGAGGC TCCTGGTTTC TCACGGGGGT CCTGGGCTCG 
CAGCCAGTAG GAGGGCAGGC TCACATGGTC CTTGTCACCA AGGTCTCCAG GTACTCACTC 
TGGTTTAAAC AGATCATGAA CTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016876301.1
CDS	4..1407
Translation	MSRTRKRQEGSTQLHRSCPEAPAAGTSPSLDFGCVCSPVPALRVGMAGCVPLLQGLVLVLALHRVEPSATSLKERHGLHSDSACTGVQESLFLPASKANDVLVRWKRAGSYLLEELFEGNLEKECYEEICVYEEAREVFENEVVTDEFWRRYKGGSPCISQPCLHNGSCQDSIWGYTCTCSPGYEGSNCELAKNECHPERTDGCQHFCLPGQESYTCSCAQGYRLGEDHKQCVPHDQCACGVLTSEKRAPDLQDLPWQVKLTNSEGKDFCGGVIIRENFVLTTAKCSLLHRNITVKTYFNRTSQDPLMIKITHVHVHMRYDADAGENDLSLLELEWPIQCPGAGLPVCTPEKDFAEHLLIPRTRGLLSGWARNGTDLGNSLTTRPVTLVEGEECGQVLNVTVTTRTYCERSSVAAMHWMDGSVVTREHRGSWFLTGVLGSQPVGGQAHMVLVTKVSRYSLWFKQIMN

Target ORF information:

RefSeq Version	XM_017020812.1
Organism	Homo sapiens(human)
Definition	Homo sapiens protein Z, vitamin K dependent plasma glycoprotein (PROZ), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017020812.1

ORF Insert Sequence:

ATGAGTAGAA CGAGAAAACG TCAGGAGGGA AGCACACAGC TGCACAGGTC GTGCCCCGAG 
GCTCCTGCTG CCGGCACCTC CCCCAGCCTG GACTTTGGCT GTGTTTGTAG CCCTGTCCCA 
GCGCTCCGGG TGGGAATGGC AGGCTGCGTC CCACTGCTCC AGGGCCTGGT CCTGGTCCTC 
GCCCTCCATC GTGTGGAGCC CTCAGCCACT TCACTGAAGG AACGACATGG ACTCCATTCT 
GACTCTGCCT GCACAGGCGT CCAGGAAAGC TTATTTCTCC CGGCCTCCAA AGCAAACGAC 
GTTCTGGTGA GGTGGAAGCG TGCGGGCTCC TATCTTCTGG AAGAACTCTT CGAGGGAAAC 
TTGGAAAAAG AATGTTATGA AGAAATCTGT GTCTATGAAG AAGCAAGAGA AGTGTTTGAA 
AATGAAGTAG TCACTGATGA ATTCTGGAGA CGATATAAGG GCGGCTCCCC GTGCATCTCC 
CAGCCCTGCC TCCACAACGG CTCTTGCCAG GACAGCATCT GGGGCTACAC CTGCACCTGC 
TCCCCCGGCT ATGAGGGCAG CAACTGCGAG CTGGCTAAAA ATGAATGTCA CCCAGAGCGG 
ACTGATGGGT GTCAACACTT CTGCCTCCCA GGACAGGAAT CCTACACATG CAGCTGTGCT 
CAGGGCTACA GGCTTGGTGA GGACCACAAA CAGTGTGTGC CCCACGACCA GTGTGCCTGC 
GGGGTGCTGA CCTCTGAGAA GCGTGCACCG GATCTACAGG ACCTCCCGTG GCAGGTAAAG 
TTAACAAATT CCGAAGGAAA AGACTTCTGT GGTGGTGTTA TAATACGGGA AAATTTTGTA 
CTGACAACAG CAAAATGTTC ACTGTTACAC AGGAATATTA CTGTAAAAAC ATATTTTAAC 
AGAACGAGCC AAGACCCGCT GATGATCAAG ATAACGCACG TCCATGTGCA CATGCGGTAT 
GACGCGGACG CGGGGGAGAA TGACCTGTCA CTGCTGGAGC TGGAGTGGCC CATCCAGTGC 
CCAGGTGCGG GGCTCCCCGT GTGCACCCCT GAGAAAGACT TCGCTGAGCA CCTCCTCATC 
CCACGCACCA GGGGCCTCCT CAGCGGCTGG GCACGCAATG GCACTGACCT GGGCAACTCG 
CTGACCACGC GGCCTGTCAC ACTTGTGGAG GGGGAGGAGT GCGGGCAGGT CCTGAATGTG 
ACTGTCACCA CCAGGACCTA CTGTGAGAGA AGCAGCGTGG CGGCCATGCA CTGGATGGAT 
GGAAGTGTGG TCACCAGAGA ACACAGAGGC TCCTGGTTTC TCACGGGGGT CCTGGGCTCG 
CAGCCAGTAG GAGGGCAGGC TCACATGGTC CTTGTCACCA AGGTCTCCAG GTACTCACTC 
TGGTTTAAAC AGATCATGAA CTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PROZ ( XM_017020813.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016876302.1 Homo sapiens protein Z, vitamin K dependent plasma glycoprotein (PROZ), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu84672
Clone ID Related Accession (Same CDS sequence)	XM_017020813.1
Accession Version	XM_017020813.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1005bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	vitamin K-dependent protein Z isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000013.11) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCAGGCT GCGTCCCACT GCTCCAGGGC CTGGTCCTGG TCCTCGCCCT CCATCGTGTG 
GAGCCCTCAG CCACTTCACT GAAGGAACGA CATGGACTCC ATTCTGACTC TGCCTGCACA 
GGCGTCCAGG AAAGCTTATT TCTCCCGGCC TCCAAAGCAA ACGACGTTCT GGTGAGGTGG 
AAGCGTGCGG GCTCCTATCT TCTGGAAGAA CTCTTCGAGG GAAACTTGGA AAAAGAATGT 
TATGAAGAAA TCTGTGTCTA TGAAGAAGCA AGAGAAGTGT TTGAAAATGA AGTAGTCACT 
GATGAATTCT GGAGACGATA TAAGGGCGGC TCCCCGTGCA TCTCCCAGCC CTGCCTCCAC 
AACGGCTCTT GCCAGGACAG CATCTGGGGC TACACCTGCA CCTGCTCCCC CGGCTATGAG 
GGCAGCAACT GCGAGCTGGC TAAAAATGAA TGTCACCCAG AGCGGACTGA TGGGTGTCAA 
CACTTCTGCC TCCCAGGACA GGAATCCTAC ACATGCAGCT GTGCTCAGGG CTACAGGCTT 
GGTGAGGACC ACAAACAGTG TGTGCCCCAC GACCAGTGTG CCTGCGGGGT GCTGACCTCT 
GAGAAGCGTG CACCGGATCT ACAGGACCTC CCGTGGCAGG TAAAGTTAAC AAATTCCGAA 
GGAAAAGACT TCTGTGGTGG TGTTATAATA CGGGAAAATT TTGTACTGAC AACAGCAAAA 
TGTTCACTGT TACACAGGAA TATTACTGTA AAAACATATT TTAACAGAAC GAGCCAAGAC 
CCGCTGATGA TCAAGATAAC GCACGTCCAT GTGCACATGC GGTATGACGC GGACGCGGGG 
GAGAATGACC TGTCACTGCT GGAGCTGGAG TGGCCCATCC AGTGCCCAGG ACCTACTGTG 
AGAGAAGCAG CGTGGCGGCC ATGCACTGGA TGGATGGAAG TGTGGTCACC AGAGAACACA 
GAGGCTCCTG GTTTCTCACG GGGGTCCTGG GCTCGCAGCC AGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016876302.1
CDS	122..1126
Translation	MAGCVPLLQGLVLVLALHRVEPSATSLKERHGLHSDSACTGVQESLFLPASKANDVLVRWKRAGSYLLEELFEGNLEKECYEEICVYEEAREVFENEVVTDEFWRRYKGGSPCISQPCLHNGSCQDSIWGYTCTCSPGYEGSNCELAKNECHPERTDGCQHFCLPGQESYTCSCAQGYRLGEDHKQCVPHDQCACGVLTSEKRAPDLQDLPWQVKLTNSEGKDFCGGVIIRENFVLTTAKCSLLHRNITVKTYFNRTSQDPLMIKITHVHVHMRYDADAGENDLSLLELEWPIQCPGPTVREAAWRPCTGWMEVWSPENTEAPGFSRGSWARSQ

Target ORF information:

RefSeq Version	XM_017020813.1
Organism	Homo sapiens(human)
Definition	Homo sapiens protein Z, vitamin K dependent plasma glycoprotein (PROZ), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017020813.1

ORF Insert Sequence:

ATGGCAGGCT GCGTCCCACT GCTCCAGGGC CTGGTCCTGG TCCTCGCCCT CCATCGTGTG 
GAGCCCTCAG CCACTTCACT GAAGGAACGA CATGGACTCC ATTCTGACTC TGCCTGCACA 
GGCGTCCAGG AAAGCTTATT TCTCCCGGCC TCCAAAGCAA ACGACGTTCT GGTGAGGTGG 
AAGCGTGCGG GCTCCTATCT TCTGGAAGAA CTCTTCGAGG GAAACTTGGA AAAAGAATGT 
TATGAAGAAA TCTGTGTCTA TGAAGAAGCA AGAGAAGTGT TTGAAAATGA AGTAGTCACT 
GATGAATTCT GGAGACGATA TAAGGGCGGC TCCCCGTGCA TCTCCCAGCC CTGCCTCCAC 
AACGGCTCTT GCCAGGACAG CATCTGGGGC TACACCTGCA CCTGCTCCCC CGGCTATGAG 
GGCAGCAACT GCGAGCTGGC TAAAAATGAA TGTCACCCAG AGCGGACTGA TGGGTGTCAA 
CACTTCTGCC TCCCAGGACA GGAATCCTAC ACATGCAGCT GTGCTCAGGG CTACAGGCTT 
GGTGAGGACC ACAAACAGTG TGTGCCCCAC GACCAGTGTG CCTGCGGGGT GCTGACCTCT 
GAGAAGCGTG CACCGGATCT ACAGGACCTC CCGTGGCAGG TAAAGTTAAC AAATTCCGAA 
GGAAAAGACT TCTGTGGTGG TGTTATAATA CGGGAAAATT TTGTACTGAC AACAGCAAAA 
TGTTCACTGT TACACAGGAA TATTACTGTA AAAACATATT TTAACAGAAC GAGCCAAGAC 
CCGCTGATGA TCAAGATAAC GCACGTCCAT GTGCACATGC GGTATGACGC GGACGCGGGG 
GAGAATGACC TGTCACTGCT GGAGCTGGAG TGGCCCATCC AGTGCCCAGG ACCTACTGTG 
AGAGAAGCAG CGTGGCGGCC ATGCACTGGA TGGATGGAAG TGTGGTCACC AGAGAACACA 
GAGGCTCCTG GTTTCTCACG GGGGTCCTGG GCTCGCAGCC AGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Low plasma protein Z levels are associated with an increased risk for perioperative bleedings.
European journal of haematology(2018 Jan)
Hinterleitner C,Kreisselmeier KP,Pecher AC,Mauz PS,Kanz L,Kopp HG,Jaschonek KG

The Role of Protein Z and Protein Z-Dependent Protease Inhibitor Polymorphisms in the Development of Prosthetic Heart Valve Thrombosis.
The Journal of heart valve disease26(4)460-466(2017 Jul)
Karakoyun S,Ozan G?rsoy M,Kal??k M,Yesin M,G?nd?z S,Ali Astarc?o?lu M,Bayram Z,?akal B,Bayam E,?zkan M

The gene for human protein Z is localized to chromosome 13 at band q34 and is coded by eight regular exons and one alternative exon.
Biochemistry37(19)6838-46(1998 May)
Fujimaki K,Yamazaki T,Taniwaki M,Ichinose A

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PROZ cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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