Gene Symbol | TNFRSF10A |
Entrez Gene ID | 8797 |
Full Name | TNF receptor superfamily member 10a |
Synonyms | APO2,CD261,DR4,TRAILR-1,TRAILR1 |
General protein information |
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Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Summary | The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL), and thus transduces cell death signal and induces cell apoptosis. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. [provided by RefSeq, Jul 2008]. |
Disorder MIM: |