PABPC4 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	PABPC4
Entrez Gene ID	8761
Full Name	poly(A) binding protein cytoplasmic 4
Synonyms	APP-1,APP1,PABP4,iPABP
General protein information	Preferred Names poly(A) binding protein cytoplasmic 4 Names polyadenylate-binding protein 4 PABP-4 activated-platelet protein 1 inducible poly(A)-binding protein poly(A) binding protein, cytoplasmic 4 (inducible form) poly(A)-binding protein 4
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 1 Map Location: 1p34.3
Summary	Poly(A)-binding proteins (PABPs) bind to the poly(A) tail present at the 3-prime ends of most eukaryotic mRNAs. PABPC4 or IPABP (inducible PABP) was isolated as an activation-induced T-cell mRNA encoding a protein. Activation of T cells increased PABPC4 mRNA levels in T cells approximately 5-fold. PABPC4 contains 4 RNA-binding domains and proline-rich C terminus. PABPC4 is localized primarily to the cytoplasm. It is suggested that PABPC4 might be necessary for regulation of stability of labile mRNA species in activated T cells. PABPC4 was also identified as an antigen, APP1 (activated-platelet protein-1), expressed on thrombin-activated rabbit platelets. PABPC4 may also be involved in the regulation of protein translation in platelets and megakaryocytes or may participate in the binding or stabilization of polyadenylates in platelet dense granules. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008].
Disorder MIM:	603407

mRNA and Protein(s)

mRNA	Protein	Name
NM_001135654.1	NP_001129126.1	polyadenylate-binding protein 4 isoform 3
NM_003819.3	NP_003810.1	polyadenylate-binding protein 4 isoform 2
NM_001135653.2	NP_001129125.1	polyadenylate-binding protein 4 isoform 1
NM_001135653.1	NP_001129125.1	polyadenylate-binding protein 4 isoform 1
NM_001135654.2	NP_001129126.1	polyadenylate-binding protein 4 isoform 3
NM_003819.4	NP_003810.1	polyadenylate-binding protein 4 isoform 2

Pathways from BioSystems

Homologies

Danio rerio (zebrafish)	pabpc4	NP_958453.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP011092	XP_309558.3
Arabidopsis thaliana (thale cress)	PAB5	NP_177322.2
Homo sapiens (human)	PABPC4	NP_001129125.1
Pan troglodytes (chimpanzee)	PABPC4	XP_513344.3
Mus musculus (house mouse)	Pabpc4	NP_570951.2
Rattus norvegicus (Norway rat)	Pabpc4	NP_001094008.1
Drosophila melanogaster (fruit fly)	pAbp	NP_725749.1
	PABPC4	XP_001113342.2
Gallus gallus (chicken)	PABPC4	XP_004947928.1
Canis lupus familiaris (dog)	PABPC4	XP_005628959.1
Bos taurus (cattle)	PABPC4	NP_001077193.1
Arabidopsis thaliana (thale cress)	PAB3	NP_173690.1

Gene Ontology
Bibliography

Related articles in PubMed

Identification of a Nuclear Exosome Decay Pathway for Processed Transcripts.
Meola N, Domanski M, Karadoulama E, Chen Y, Gentil C, Pultz D, Vitting-Seerup K, Lykke-Andersen S, Andersen JS, Sandelin A, Jensen TH
Molecular cell64(3)520-533(2016 Nov)

Gender-specific association between the cytoplasmic poly(A) binding protein 4 rs4660293 single nucleotide polymorphism and serum lipid levels.
Wu J, Yin RX, Guo T, Lin QZ, Shen SW, Sun JQ, Shi GY, Wu JZ, Yang DZ, Lin WX
Molecular medicine reports12(3)3476-86(2015 Sep)

Discovery and refinement of loci associated with lipid levels.
Willer CJ, Schmidt EM, Sengupta S, Peloso GM, Gustafsson S, Kanoni S, Ganna A, Chen J, Buchkovich ML, Mora S, Beckmann JS, Bragg-Gresham JL, Chang HY, Demirkan A, Den Hertog HM, Do R, Donnelly LA, Ehret GB, Esko T, Feitosa MF, Ferreira T, Fischer K, Fontanillas P, Fraser RM, Freitag DF, Gurdasani D, Heikkil? K, Hypp?nen E, Isaacs A, Jackson AU, Johansson ?, Johnson T, Kaakinen M, Kettunen J, Kleber ME, Li X, Luan J, Lyytik?inen LP, Magnusson PKE, Mangino M, Mihailov E, Montasser ME, M?ller-Nurasyid M, Nolte IM, O'Connell JR, Palmer CD, Perola M, Petersen AK, Sanna S, Saxena R, Service SK, Shah S, Shungin D, Sidore C, Song C, Strawbridge RJ, Surakka I, Tanaka T, Teslovich TM, Thorleifsson G, Van den Herik EG, Voight BF, Volcik KA, Waite LL, Wong A, Wu Y, Zhang W, Absher D, Asiki G, Barroso I, Been LF, Bolton JL, Bonnycastle LL, Brambilla P, Burnett MS, Cesana G, Dimitriou M, Doney ASF, D?ring A, Elliott P, Epstein SE, Ingi Eyjolfsson G, Gigante B, Goodarzi MO, Grallert H, Gravito ML, Groves CJ, Hallmans G, Hartikainen AL, Hayward C, Hernandez D, Hicks AA, Holm H, Hung YJ, Illig T, Jones MR, Kaleebu P, Kastelein JJP, Khaw KT, Kim E, Klopp N, Komulainen P, Kumari M, Langenberg C, Lehtim?ki T, Lin SY, Lindstr?m J, Loos RJF, Mach F, McArdle WL, Meisinger C, Mitchell BD, M?ller G, Nagaraja R, Narisu N, Nieminen TVM, Nsubuga RN, Olafsson I, Ong KK, Palotie A, Papamarkou T, Pomilla C, Pouta A, Rader DJ, Reilly MP, Ridker PM, Rivadeneira F, Rudan I, Ruokonen A, Samani N, Scharnagl H, Seeley J, Silander K, Stan??kov? A, Stirrups K, Swift AJ, Tiret L, Uitterlinden AG, van Pelt LJ, Vedantam S, Wainwright N, Wijmenga C, Wild SH, Willemsen G, Wilsgaard T, Wilson JF, Young EH, Zhao JH, Adair LS, Arveiler D, Assimes TL, Bandinelli S, Bennett F, Bochud M, Boehm BO, Boomsma DI, Borecki IB, Bornstein SR, Bovet P, Burnier M, Campbell H, Chakravarti A, Chambers JC, Chen YI, Collins FS, Cooper RS, Danesh J, Dedoussis G, de Faire U, Feranil AB, Ferri?res J, Ferrucci L, Freimer NB, Gieger C, Groop LC, Gudnason V, Gyllensten U, Hamsten A, Harris TB, Hingorani A, Hirschhorn JN, Hofman A, Hovingh GK, Hsiung CA, Humphries SE, Hunt SC, Hveem K, Iribarren C, J?rvelin MR, Jula A, K?h?nen M, Kaprio J, Kes?niemi A, Kivimaki M, Kooner JS, Koudstaal PJ, Krauss RM, Kuh D, Kuusisto J, Kyvik KO, Laakso M, Lakka TA, Lind L, Lindgren CM, Martin NG, M?rz W, McCarthy MI, McKenzie CA, Meneton P, Metspalu A, Moilanen L, Morris AD, Munroe PB, Nj?lstad I, Pedersen NL, Power C, Pramstaller PP, Price JF, Psaty BM, Quertermous T, Rauramaa R, Saleheen D, Salomaa V, Sanghera DK, Saramies J, Schwarz PEH, Sheu WH, Shuldiner AR, Siegbahn A, Spector TD, Stefansson K, Strachan DP, Tayo BO, Tremoli E, Tuomilehto J, Uusitupa M, van Duijn CM, Vollenweider P, Wallentin L, Wareham NJ, Whitfield JB, Wolffenbuttel BHR, Ordovas JM, Boerwinkle E, Palmer CNA, Thorsteinsdottir U, Chasman DI, Rotter JI, Franks PW, Ripatti S, Cupples LA, Sandhu MS, Rich SS, Boehnke M, Deloukas P, Kathiresan S, Mohlke KL, Ingelsson E, Abecasis GR,
Nature genetics45(11)1274-1283(2013 Nov)

Cytoplasmic poly(A) binding protein 4 is highly expressed in human colorectal cancer and correlates with better prognosis.
Liu D, Yin B, Wang Q, Ju W, Chen Y, Qiu H, Li J, Peng X, Lu C
Journal of genetics and genomics = Yi chuan xue bao39(8)369-74(2012 Aug)

Depletion of nuclear poly(A) binding protein PABPN1 produces a compensatory response by cytoplasmic PABP4 and PABP5 in cultured human cells.
Bhattacharjee RB, Bag J
PloS one7(12)e53036(2012)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The PABPC4 rs4660293 SNP is associated with serum lipid levels.
Title: Gender-specific association between the cytoplasmic poly(A) binding protein 4 rs4660293 single nucleotide polymorphism and serum lipid levels.

PABPC4 is highly expressed in human colorectal cancer.
Title: Cytoplasmic poly(A) binding protein 4 is highly expressed in human colorectal cancer and correlates with better prognosis.

although function of PABPN1 may be compensated by nuclear translocation of PABP4 and perhaps by increase the cytoplasmic abundance of PABP5, these were not sufficient to prevent apoptosis of cells. PABPN1 may have an anti apoptotic role in mammalian cells
Title: Depletion of nuclear poly(A) binding protein PABPN1 produces a compensatory response by cytoplasmic PABP4 and PABP5 in cultured human cells.

Nuclear relocalisation of cytoplasmic poly(A)-binding proteins PABP1 and PABP4 in response to UV irradiation reveals mRNA-dependent export
Title: Nuclear relocalisation of cytoplasmic poly(A)-binding proteins PABP1 and PABP4 in response to UV irradiation reveals mRNA-dependent export of metazoan PABPs.

RNA binding masks nuclear import signals within the cytoplasmic poly(A) binding protein RNA recognition motifs, thereby ensuring ef fi cient cytoplasmic retention of this protein in normal cells
Title: Importin alpha-mediated nuclear import of cytoplasmic poly(A) binding protein occurs as a direct consequence of cytoplasmic mRNA depletion.

The following PABPC4 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the PABPC4 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu24714	NM_001135654.2 Latest version!	Homo sapiens poly(A) binding protein cytoplasmic 4 (PABPC4), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
OHu24716	NM_001135653.2 Latest version!	Homo sapiens poly(A) binding protein cytoplasmic 4 (PABPC4), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$265.30 $379.00
OHu24792	NM_003819.4 Latest version!	Homo sapiens poly(A) binding protein cytoplasmic 4 (PABPC4), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$384.30 $549.00
View Old Accession Versions >>
OHu24716	NM_001135653.1	Homo sapiens poly(A) binding protein cytoplasmic 4 (PABPC4), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$265.30 $379.00
OHu24714	NM_001135654.1	Homo sapiens poly(A) binding protein cytoplasmic 4 (PABPC4), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
OHu24792	NM_003819.3	Homo sapiens poly(A) binding protein cytoplasmic 4 (PABPC4), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$384.30 $549.00
Hide Old Accession Versions >>

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Reference Sequences (Refseq)

PABPC4 ( NM_001135654.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001129126.1 Homo sapiens poly(A) binding protein cytoplasmic 4 (PABPC4), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu24714
Clone ID Related Accession (Same CDS sequence)	NM_001135654.1 , NM_001135654.2
Accession Version	NM_001135654.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1896bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-06-23
Organism	Homo sapiens(human)
Product	polyadenylate-binding protein 4 isoform 3
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DB455681.1, BC029969.1 and BC065540.1. Transcript Variant: This variant (3) lacks an in-frame coding exon, as compared to variant 1. The resulting isoform (3) lacks an internal segment, as compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC065540.1, SRR1803611.196905.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1966682, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAACGCTG CGGCCAGCAG CTACCCCATG GCCTCCCTGT ACGTGGGCGA CCTGCATTCG 
GACGTCACCG AGGCCATGCT GTACGAAAAG TTCAGCCCCG CGGGGCCTGT GCTGTCCATC 
CGGGTCTGCC GCGATATGAT CACCCGCCGC TCCCTGGGCT ATGCCTACGT CAACTTCCAG 
CAGCCGGCCG ACGCTGAGCG GGCTTTGGAC ACCATGAACT TTGATGTGAT TAAGGGAAAG 
CCAATCCGCA TCATGTGGTC TCAGAGGGAT CCCTCTTTGA GAAAATCTGG TGTGGGAAAC 
GTCTTCATCA AGAACCTGGA CAAATCTATA GATAACAAGG CACTTTATGA TACTTTTTCT 
GCTTTTGGAA ACATACTGTC CTGCAAGGTG GTGTGTGATG AGAACGGCTC TAAGGGTTAT 
GCCTTTGTCC ACTTCGAGAC CCAAGAGGCT GCCGACAAGG CCATCGAGAA GATGAATGGC 
ATGCTCCTCA ATGACCGCAA AGTATTTGTG GGCAGATTCA AGTCTCGCAA AGAGCGGGAA 
GCTGAGCTTG GAGCCAAAGC CAAGGAATTC ACCAATGTTT ATATCAAAAA CTTTGGGGAA 
GAGGTGGATG ATGAGAGTCT GAAAGAGCTA TTCAGTCAGT TTGGTAAGAC CCTAAGTGTC 
AAGGTGATGA GAGATCCCAA TGGGAAATCC AAAGGCTTTG GCTTTGTGAG TTACGAAAAA 
CACGAGGATG CCAATAAGGC TGTGGAAGAG ATGAATGGAA AAGAAATAAG TGGTAAAATC 
ATATTTGTAG GCCGTGCACA AAAGAAAGTA GAACGGCAGG CAGAGTTAAA ACGGAAATTT 
GAACAGTTGA AACAGGAGAG AATTAGTCGA TATCAGGGGG TGAATCTCTA CATTAAGAAC 
TTGGATGACA CTATTGATGA TGAGAAATTA AGGAAAGAAT TTTCTCCTTT TGGATCAATT 
ACCAGTGCTA AGGTAATGCT GGAGGATGGA AGAAGCAAAG GGTTTGGCTT CGTCTGCTTC 
TCATCTCCTG AAGAAGCAAC CAAAGCAGTC ACTGAGATGA ATGGACGCAT TGTGGGCTCC 
AAGCCACTAT ATGTTGCCCT GGCCCAGAGG AAGGAAGAGA GAAAGGCTCA CCTGACCAAC 
CAGTATATGC AACGAGTGGC TGGAATGAGA GCACTTCCTG CCAATGCCAT CTTAAATCAG 
TTCCAGCCTG CAGCGGGTGG CTACTTTGTG CCAGCAGTCC CACAGGCTCA GGGAAGGCCT 
CCATATTATA CACCTAACCA GTTAGCACAG ATGAGGCCTA ATCCACGCTG GCAGCAAGGT 
GGGAGACCTC AAGGCTTCCA AGGAATGCCA AGTGCTATAC GCCAGTCTGG GCCTCGTCCA 
ACTCTTCGCC ATCTGGCTCC AACTGGTAAT GCTCCGGCCT CTCGTGGCCT CCCTACTACC 
ACTCAGAGAG TCGGCGTTCC CACAGCTGTG CAGAACTTAG CGCCACGCGC TGCTGTTGCT 
GCTGCTGCTC CCCGGGCTGT TGCCCCCTAC AAATACGCCT CCAGTGTCCG CAGCCCTCAT 
CCTGCCATAC AGCCTCTGCA GGCACCCCAG CCTGCGGTCC ATGTGCAGGG GCAGGAGCCA 
CTGACTGCCT CCATGCTGGC TGCAGCACCC CCCCAGGAAC AGAAGCAGAT GCTGGGAGAA 
CGCTTGTTCC CACTCATCCA AACAATGCAT TCAAATCTGG CTGGGAAGAT CACGGGAATG 
CTGCTGGAGA TAGACAACTC TGAGCTGCTG CACATGTTAG AGTCCCCCGA GTCTCTCCGC 
TCCAAGGTGG ATGAAGCTGT AGCAGTTCTA CAGGCTCATC ATGCCAAGAA AGAAGCTGCC 
CAGAAGGTGG GCGCTGTTGC TGCTGCTACC TCTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001129126.1
CDS	899..2794
Translation	MNAAASSYPMASLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALDTMNFDVIKGKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDENGSKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFKSRKEREAELGAKAKEFTNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPNGKSKGFGFVSYEKHEDANKAVEEMNGKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVNLYIKNLDDTIDDEKLRKEFSPFGSITSAKVMLEDGRSKGFGFVCFSSPEEATKAVTEMNGRIVGSKPLYVALAQRKEERKAHLTNQYMQRVAGMRALPANAILNQFQPAAGGYFVPAVPQAQGRPPYYTPNQLAQMRPNPRWQQGGRPQGFQGMPSAIRQSGPRPTLRHLAPTGNAPASRGLPTTTQRVGVPTAVQNLAPRAAVAAAAPRAVAPYKYASSVRSPHPAIQPLQAPQPAVHVQGQEPLTASMLAAAPPQEQKQMLGERLFPLIQTMHSNLAGKITGMLLEIDNSELLHMLESPESLRSKVDEAVAVLQAHHAKKEAAQKVGAVAAATS

Target ORF information:

RefSeq Version	NM_001135654.1
Organism	Homo sapiens(human)
Definition	Homo sapiens poly(A) binding protein cytoplasmic 4 (PABPC4), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001135654.1

ORF Insert Sequence:

ATGAACGCTG CGGCCAGCAG CTACCCCATG GCCTCCCTGT ACGTGGGCGA CCTGCATTCG 
GACGTCACCG AGGCCATGCT GTACGAAAAG TTCAGCCCCG CGGGGCCTGT GCTGTCCATC 
CGGGTCTGCC GCGATATGAT CACCCGCCGC TCCCTGGGCT ATGCCTACGT CAACTTCCAG 
CAGCCGGCCG ACGCTGAGCG GGCTTTGGAC ACCATGAACT TTGATGTGAT TAAGGGAAAG 
CCAATCCGCA TCATGTGGTC TCAGAGGGAT CCCTCTTTGA GAAAATCTGG TGTGGGAAAC 
GTCTTCATCA AGAACCTGGA CAAATCTATA GATAACAAGG CACTTTATGA TACTTTTTCT 
GCTTTTGGAA ACATACTGTC CTGCAAGGTG GTGTGTGATG AGAACGGCTC TAAGGGTTAT 
GCCTTTGTCC ACTTCGAGAC CCAAGAGGCT GCCGACAAGG CCATCGAGAA GATGAATGGC 
ATGCTCCTCA ATGACCGCAA AGTATTTGTG GGCAGATTCA AGTCTCGCAA AGAGCGGGAA 
GCTGAGCTTG GAGCCAAAGC CAAGGAATTC ACCAATGTTT ATATCAAAAA CTTTGGGGAA 
GAGGTGGATG ATGAGAGTCT GAAAGAGCTA TTCAGTCAGT TTGGTAAGAC CCTAAGTGTC 
AAGGTGATGA GAGATCCCAA TGGGAAATCC AAAGGCTTTG GCTTTGTGAG TTACGAAAAA 
CACGAGGATG CCAATAAGGC TGTGGAAGAG ATGAATGGAA AAGAAATAAG TGGTAAAATC 
ATATTTGTAG GCCGTGCACA AAAGAAAGTA GAACGGCAGG CAGAGTTAAA ACGGAAATTT 
GAACAGTTGA AACAGGAGAG AATTAGTCGA TATCAGGGGG TGAATCTCTA CATTAAGAAC 
TTGGATGACA CTATTGATGA TGAGAAATTA AGGAAAGAAT TTTCTCCTTT TGGATCAATT 
ACCAGTGCTA AGGTAATGCT GGAGGATGGA AGAAGCAAAG GGTTTGGCTT CGTCTGCTTC 
TCATCTCCTG AAGAAGCAAC CAAAGCAGTC ACTGAGATGA ATGGACGCAT TGTGGGCTCC 
AAGCCACTAT ATGTTGCCCT GGCCCAGAGG AAGGAAGAGA GAAAGGCTCA CCTGACCAAC 
CAGTATATGC AACGAGTGGC TGGAATGAGA GCACTTCCTG CCAATGCCAT CTTAAATCAG 
TTCCAGCCTG CAGCGGGTGG CTACTTTGTG CCAGCAGTCC CACAGGCTCA GGGAAGGCCT 
CCATATTATA CACCTAACCA GTTAGCACAG ATGAGGCCTA ATCCACGCTG GCAGCAAGGT 
GGGAGACCTC AAGGCTTCCA AGGAATGCCA AGTGCTATAC GCCAGTCTGG GCCTCGTCCA 
ACTCTTCGCC ATCTGGCTCC AACTGGTAAT GCTCCGGCCT CTCGTGGCCT CCCTACTACC 
ACTCAGAGAG TCGGCGTTCC CACAGCTGTG CAGAACTTAG CGCCACGCGC TGCTGTTGCT 
GCTGCTGCTC CCCGGGCTGT TGCCCCCTAC AAATACGCCT CCAGTGTCCG CAGCCCTCAT 
CCTGCCATAC AGCCTCTGCA GGCACCCCAG CCTGCGGTCC ATGTGCAGGG GCAGGAGCCA 
CTGACTGCCT CCATGCTGGC TGCAGCACCC CCCCAGGAAC AGAAGCAGAT GCTGGGAGAA 
CGCTTGTTCC CACTCATCCA AACAATGCAT TCAAATCTGG CTGGGAAGAT CACGGGAATG 
CTGCTGGAGA TAGACAACTC TGAGCTGCTG CACATGTTAG AGTCCCCCGA GTCTCTCCGC 
TCCAAGGTGG ATGAAGCTGT AGCAGTTCTA CAGGCTCATC ATGCCAAGAA AGAAGCTGCC 
CAGAAGGTGG GCGCTGTTGC TGCTGCTACC TCTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PABPC4 ( NM_001135654.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001129126.1 Homo sapiens poly(A) binding protein cytoplasmic 4 (PABPC4), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu24714
Clone ID Related Accession (Same CDS sequence)	NM_001135654.1 , NM_001135654.2
Accession Version	NM_001135654.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1896bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-27
Organism	Homo sapiens(human)
Product	polyadenylate-binding protein 4 isoform 3
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DB455681.1, BC029969.1 and BC065540.1. On May 31, 2019 this sequence version replaced NM_001135654.1. Transcript Variant: This variant (3) lacks an in-frame coding exon, as compared to variant 1. The resulting isoform (3) lacks an internal segment, as compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC065540.1, SRR1803611.196905.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1966682, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAACGCTG CGGCCAGCAG CTACCCCATG GCCTCCCTGT ACGTGGGCGA CCTGCATTCG 
GACGTCACCG AGGCCATGCT GTACGAAAAG TTCAGCCCCG CGGGGCCTGT GCTGTCCATC 
CGGGTCTGCC GCGATATGAT CACCCGCCGC TCCCTGGGCT ATGCCTACGT CAACTTCCAG 
CAGCCGGCCG ACGCTGAGCG GGCTTTGGAC ACCATGAACT TTGATGTGAT TAAGGGAAAG 
CCAATCCGCA TCATGTGGTC TCAGAGGGAT CCCTCTTTGA GAAAATCTGG TGTGGGAAAC 
GTCTTCATCA AGAACCTGGA CAAATCTATA GATAACAAGG CACTTTATGA TACTTTTTCT 
GCTTTTGGAA ACATACTGTC CTGCAAGGTG GTGTGTGATG AGAACGGCTC TAAGGGTTAT 
GCCTTTGTCC ACTTCGAGAC CCAAGAGGCT GCCGACAAGG CCATCGAGAA GATGAATGGC 
ATGCTCCTCA ATGACCGCAA AGTATTTGTG GGCAGATTCA AGTCTCGCAA AGAGCGGGAA 
GCTGAGCTTG GAGCCAAAGC CAAGGAATTC ACCAATGTTT ATATCAAAAA CTTTGGGGAA 
GAGGTGGATG ATGAGAGTCT GAAAGAGCTA TTCAGTCAGT TTGGTAAGAC CCTAAGTGTC 
AAGGTGATGA GAGATCCCAA TGGGAAATCC AAAGGCTTTG GCTTTGTGAG TTACGAAAAA 
CACGAGGATG CCAATAAGGC TGTGGAAGAG ATGAATGGAA AAGAAATAAG TGGTAAAATC 
ATATTTGTAG GCCGTGCACA AAAGAAAGTA GAACGGCAGG CAGAGTTAAA ACGGAAATTT 
GAACAGTTGA AACAGGAGAG AATTAGTCGA TATCAGGGGG TGAATCTCTA CATTAAGAAC 
TTGGATGACA CTATTGATGA TGAGAAATTA AGGAAAGAAT TTTCTCCTTT TGGATCAATT 
ACCAGTGCTA AGGTAATGCT GGAGGATGGA AGAAGCAAAG GGTTTGGCTT CGTCTGCTTC 
TCATCTCCTG AAGAAGCAAC CAAAGCAGTC ACTGAGATGA ATGGACGCAT TGTGGGCTCC 
AAGCCACTAT ATGTTGCCCT GGCCCAGAGG AAGGAAGAGA GAAAGGCTCA CCTGACCAAC 
CAGTATATGC AACGAGTGGC TGGAATGAGA GCACTTCCTG CCAATGCCAT CTTAAATCAG 
TTCCAGCCTG CAGCGGGTGG CTACTTTGTG CCAGCAGTCC CACAGGCTCA GGGAAGGCCT 
CCATATTATA CACCTAACCA GTTAGCACAG ATGAGGCCTA ATCCACGCTG GCAGCAAGGT 
GGGAGACCTC AAGGCTTCCA AGGAATGCCA AGTGCTATAC GCCAGTCTGG GCCTCGTCCA 
ACTCTTCGCC ATCTGGCTCC AACTGGTAAT GCTCCGGCCT CTCGTGGCCT CCCTACTACC 
ACTCAGAGAG TCGGCGTTCC CACAGCTGTG CAGAACTTAG CGCCACGCGC TGCTGTTGCT 
GCTGCTGCTC CCCGGGCTGT TGCCCCCTAC AAATACGCCT CCAGTGTCCG CAGCCCTCAT 
CCTGCCATAC AGCCTCTGCA GGCACCCCAG CCTGCGGTCC ATGTGCAGGG GCAGGAGCCA 
CTGACTGCCT CCATGCTGGC TGCAGCACCC CCCCAGGAAC AGAAGCAGAT GCTGGGAGAA 
CGCTTGTTCC CACTCATCCA AACAATGCAT TCAAATCTGG CTGGGAAGAT CACGGGAATG 
CTGCTGGAGA TAGACAACTC TGAGCTGCTG CACATGTTAG AGTCCCCCGA GTCTCTCCGC 
TCCAAGGTGG ATGAAGCTGT AGCAGTTCTA CAGGCTCATC ATGCCAAGAA AGAAGCTGCC 
CAGAAGGTGG GCGCTGTTGC TGCTGCTACC TCTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001129126.1
CDS	840..2735
Translation	MNAAASSYPMASLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALDTMNFDVIKGKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDENGSKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFKSRKEREAELGAKAKEFTNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPNGKSKGFGFVSYEKHEDANKAVEEMNGKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVNLYIKNLDDTIDDEKLRKEFSPFGSITSAKVMLEDGRSKGFGFVCFSSPEEATKAVTEMNGRIVGSKPLYVALAQRKEERKAHLTNQYMQRVAGMRALPANAILNQFQPAAGGYFVPAVPQAQGRPPYYTPNQLAQMRPNPRWQQGGRPQGFQGMPSAIRQSGPRPTLRHLAPTGNAPASRGLPTTTQRVGVPTAVQNLAPRAAVAAAAPRAVAPYKYASSVRSPHPAIQPLQAPQPAVHVQGQEPLTASMLAAAPPQEQKQMLGERLFPLIQTMHSNLAGKITGMLLEIDNSELLHMLESPESLRSKVDEAVAVLQAHHAKKEAAQKVGAVAAATS

Target ORF information:

RefSeq Version	NM_001135654.2
Organism	Homo sapiens(human)
Definition	Homo sapiens poly(A) binding protein cytoplasmic 4 (PABPC4), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001135654.2

ORF Insert Sequence:

ATGAACGCTG CGGCCAGCAG CTACCCCATG GCCTCCCTGT ACGTGGGCGA CCTGCATTCG 
GACGTCACCG AGGCCATGCT GTACGAAAAG TTCAGCCCCG CGGGGCCTGT GCTGTCCATC 
CGGGTCTGCC GCGATATGAT CACCCGCCGC TCCCTGGGCT ATGCCTACGT CAACTTCCAG 
CAGCCGGCCG ACGCTGAGCG GGCTTTGGAC ACCATGAACT TTGATGTGAT TAAGGGAAAG 
CCAATCCGCA TCATGTGGTC TCAGAGGGAT CCCTCTTTGA GAAAATCTGG TGTGGGAAAC 
GTCTTCATCA AGAACCTGGA CAAATCTATA GATAACAAGG CACTTTATGA TACTTTTTCT 
GCTTTTGGAA ACATACTGTC CTGCAAGGTG GTGTGTGATG AGAACGGCTC TAAGGGTTAT 
GCCTTTGTCC ACTTCGAGAC CCAAGAGGCT GCCGACAAGG CCATCGAGAA GATGAATGGC 
ATGCTCCTCA ATGACCGCAA AGTATTTGTG GGCAGATTCA AGTCTCGCAA AGAGCGGGAA 
GCTGAGCTTG GAGCCAAAGC CAAGGAATTC ACCAATGTTT ATATCAAAAA CTTTGGGGAA 
GAGGTGGATG ATGAGAGTCT GAAAGAGCTA TTCAGTCAGT TTGGTAAGAC CCTAAGTGTC 
AAGGTGATGA GAGATCCCAA TGGGAAATCC AAAGGCTTTG GCTTTGTGAG TTACGAAAAA 
CACGAGGATG CCAATAAGGC TGTGGAAGAG ATGAATGGAA AAGAAATAAG TGGTAAAATC 
ATATTTGTAG GCCGTGCACA AAAGAAAGTA GAACGGCAGG CAGAGTTAAA ACGGAAATTT 
GAACAGTTGA AACAGGAGAG AATTAGTCGA TATCAGGGGG TGAATCTCTA CATTAAGAAC 
TTGGATGACA CTATTGATGA TGAGAAATTA AGGAAAGAAT TTTCTCCTTT TGGATCAATT 
ACCAGTGCTA AGGTAATGCT GGAGGATGGA AGAAGCAAAG GGTTTGGCTT CGTCTGCTTC 
TCATCTCCTG AAGAAGCAAC CAAAGCAGTC ACTGAGATGA ATGGACGCAT TGTGGGCTCC 
AAGCCACTAT ATGTTGCCCT GGCCCAGAGG AAGGAAGAGA GAAAGGCTCA CCTGACCAAC 
CAGTATATGC AACGAGTGGC TGGAATGAGA GCACTTCCTG CCAATGCCAT CTTAAATCAG 
TTCCAGCCTG CAGCGGGTGG CTACTTTGTG CCAGCAGTCC CACAGGCTCA GGGAAGGCCT 
CCATATTATA CACCTAACCA GTTAGCACAG ATGAGGCCTA ATCCACGCTG GCAGCAAGGT 
GGGAGACCTC AAGGCTTCCA AGGAATGCCA AGTGCTATAC GCCAGTCTGG GCCTCGTCCA 
ACTCTTCGCC ATCTGGCTCC AACTGGTAAT GCTCCGGCCT CTCGTGGCCT CCCTACTACC 
ACTCAGAGAG TCGGCGTTCC CACAGCTGTG CAGAACTTAG CGCCACGCGC TGCTGTTGCT 
GCTGCTGCTC CCCGGGCTGT TGCCCCCTAC AAATACGCCT CCAGTGTCCG CAGCCCTCAT 
CCTGCCATAC AGCCTCTGCA GGCACCCCAG CCTGCGGTCC ATGTGCAGGG GCAGGAGCCA 
CTGACTGCCT CCATGCTGGC TGCAGCACCC CCCCAGGAAC AGAAGCAGAT GCTGGGAGAA 
CGCTTGTTCC CACTCATCCA AACAATGCAT TCAAATCTGG CTGGGAAGAT CACGGGAATG 
CTGCTGGAGA TAGACAACTC TGAGCTGCTG CACATGTTAG AGTCCCCCGA GTCTCTCCGC 
TCCAAGGTGG ATGAAGCTGT AGCAGTTCTA CAGGCTCATC ATGCCAAGAA AGAAGCTGCC 
CAGAAGGTGG GCGCTGTTGC TGCTGCTACC TCTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PABPC4 ( NM_001135653.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001129125.1 Homo sapiens poly(A) binding protein cytoplasmic 4 (PABPC4), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu24716
Clone ID Related Accession (Same CDS sequence)	NM_001135653.2 , NM_001135653.1
Accession Version	NM_001135653.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1983bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-26
Organism	Homo sapiens(human)
Product	polyadenylate-binding protein 4 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC094755.1 and BC029969.1. On Nov 23, 2018 this sequence version replaced NM_001135653.1. Transcript Variant: This variant (1) encodes the longest isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC094755.1, SRR1163655.446230.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1966682, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000372858.8/ ENSP00000361949.3 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGAACGCTG CGGCCAGCAG CTACCCCATG GCCTCCCTGT ACGTGGGCGA CCTGCATTCG 
GACGTCACCG AGGCCATGCT GTACGAAAAG TTCAGCCCCG CGGGGCCTGT GCTGTCCATC 
CGGGTCTGCC GCGATATGAT CACCCGCCGC TCCCTGGGCT ATGCCTACGT CAACTTCCAG 
CAGCCGGCCG ACGCTGAGCG GGCTTTGGAC ACCATGAACT TTGATGTGAT TAAGGGAAAG 
CCAATCCGCA TCATGTGGTC TCAGAGGGAT CCCTCTTTGA GAAAATCTGG TGTGGGAAAC 
GTCTTCATCA AGAACCTGGA CAAATCTATA GATAACAAGG CACTTTATGA TACTTTTTCT 
GCTTTTGGAA ACATACTGTC CTGCAAGGTG GTGTGTGATG AGAACGGCTC TAAGGGTTAT 
GCCTTTGTCC ACTTCGAGAC CCAAGAGGCT GCCGACAAGG CCATCGAGAA GATGAATGGC 
ATGCTCCTCA ATGACCGCAA AGTATTTGTG GGCAGATTCA AGTCTCGCAA AGAGCGGGAA 
GCTGAGCTTG GAGCCAAAGC CAAGGAATTC ACCAATGTTT ATATCAAAAA CTTTGGGGAA 
GAGGTGGATG ATGAGAGTCT GAAAGAGCTA TTCAGTCAGT TTGGTAAGAC CCTAAGTGTC 
AAGGTGATGA GAGATCCCAA TGGGAAATCC AAAGGCTTTG GCTTTGTGAG TTACGAAAAA 
CACGAGGATG CCAATAAGGC TGTGGAAGAG ATGAATGGAA AAGAAATAAG TGGTAAAATC 
ATATTTGTAG GCCGTGCACA AAAGAAAGTA GAACGGCAGG CAGAGTTAAA ACGGAAATTT 
GAACAGTTGA AACAGGAGAG AATTAGTCGA TATCAGGGGG TGAATCTCTA CATTAAGAAC 
TTGGATGACA CTATTGATGA TGAGAAATTA AGGAAAGAAT TTTCTCCTTT TGGATCAATT 
ACCAGTGCTA AGGTAATGCT GGAGGATGGA AGAAGCAAAG GGTTTGGCTT CGTCTGCTTC 
TCATCTCCTG AAGAAGCAAC CAAAGCAGTC ACTGAGATGA ATGGACGCAT TGTGGGCTCC 
AAGCCACTAT ATGTTGCCCT GGCCCAGAGG AAGGAAGAGA GAAAGGCTCA CCTGACCAAC 
CAGTATATGC AACGAGTGGC TGGAATGAGA GCACTTCCTG CCAATGCCAT CTTAAATCAG 
TTCCAGCCTG CAGCGGGTGG CTACTTTGTG CCAGCAGTCC CACAGGCTCA GGGAAGGCCT 
CCATATTATA CACCTAACCA GTTAGCACAG ATGAGGCCTA ATCCACGCTG GCAGCAAGGT 
GGGAGACCTC AAGGCTTCCA AGGAATGCCA AGTGCTATAC GCCAGTCTGG GCCTCGTCCA 
ACTCTTCGCC ATCTGGCTCC AACTGGTAAT GCTCCGGCCT CTCGTGGCCT CCCTACTACC 
ACTCAGAGAG TCGGGTCTGA GTGCCCGGAC CGCTTGGCTA TGGACTTTGG TGGGGCTGGT 
GCCGCCCAGC AAGGGCTGAC TGACAGCTGC CAGTCTGGAG GCGTTCCCAC AGCTGTGCAG 
AACTTAGCGC CACGCGCTGC TGTTGCTGCT GCTGCTCCCC GGGCTGTTGC CCCCTACAAA 
TACGCCTCCA GTGTCCGCAG CCCTCATCCT GCCATACAGC CTCTGCAGGC ACCCCAGCCT 
GCGGTCCATG TGCAGGGGCA GGAGCCACTG ACTGCCTCCA TGCTGGCTGC AGCACCCCCC 
CAGGAACAGA AGCAGATGCT GGGAGAACGC TTGTTCCCAC TCATCCAAAC AATGCATTCA 
AATCTGGCTG GGAAGATCAC GGGAATGCTG CTGGAGATAG ACAACTCTGA GCTGCTGCAC 
ATGTTAGAGT CCCCCGAGTC TCTCCGCTCC AAGGTGGATG AAGCTGTAGC AGTTCTACAG 
GCTCATCATG CCAAGAAAGA AGCTGCCCAG AAGGTGGGCG CTGTTGCTGC TGCTACCTCT 
TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001129125.1
CDS	840..2822
Translation	MNAAASSYPMASLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALDTMNFDVIKGKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDENGSKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFKSRKEREAELGAKAKEFTNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPNGKSKGFGFVSYEKHEDANKAVEEMNGKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVNLYIKNLDDTIDDEKLRKEFSPFGSITSAKVMLEDGRSKGFGFVCFSSPEEATKAVTEMNGRIVGSKPLYVALAQRKEERKAHLTNQYMQRVAGMRALPANAILNQFQPAAGGYFVPAVPQAQGRPPYYTPNQLAQMRPNPRWQQGGRPQGFQGMPSAIRQSGPRPTLRHLAPTGNAPASRGLPTTTQRVGSECPDRLAMDFGGAGAAQQGLTDSCQSGGVPTAVQNLAPRAAVAAAAPRAVAPYKYASSVRSPHPAIQPLQAPQPAVHVQGQEPLTASMLAAAPPQEQKQMLGERLFPLIQTMHSNLAGKITGMLLEIDNSELLHMLESPESLRSKVDEAVAVLQAHHAKKEAAQKVGAVAAATS

Target ORF information:

RefSeq Version	NM_001135653.2
Organism	Homo sapiens(human)
Definition	Homo sapiens poly(A) binding protein cytoplasmic 4 (PABPC4), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001135653.2

ORF Insert Sequence:

ATGAACGCTG CGGCCAGCAG CTACCCCATG GCCTCCCTGT ACGTGGGCGA CCTGCATTCG 
GACGTCACCG AGGCCATGCT GTACGAAAAG TTCAGCCCCG CGGGGCCTGT GCTGTCCATC 
CGGGTCTGCC GCGATATGAT CACCCGCCGC TCCCTGGGCT ATGCCTACGT CAACTTCCAG 
CAGCCGGCCG ACGCTGAGCG GGCTTTGGAC ACCATGAACT TTGATGTGAT TAAGGGAAAG 
CCAATCCGCA TCATGTGGTC TCAGAGGGAT CCCTCTTTGA GAAAATCTGG TGTGGGAAAC 
GTCTTCATCA AGAACCTGGA CAAATCTATA GATAACAAGG CACTTTATGA TACTTTTTCT 
GCTTTTGGAA ACATACTGTC CTGCAAGGTG GTGTGTGATG AGAACGGCTC TAAGGGTTAT 
GCCTTTGTCC ACTTCGAGAC CCAAGAGGCT GCCGACAAGG CCATCGAGAA GATGAATGGC 
ATGCTCCTCA ATGACCGCAA AGTATTTGTG GGCAGATTCA AGTCTCGCAA AGAGCGGGAA 
GCTGAGCTTG GAGCCAAAGC CAAGGAATTC ACCAATGTTT ATATCAAAAA CTTTGGGGAA 
GAGGTGGATG ATGAGAGTCT GAAAGAGCTA TTCAGTCAGT TTGGTAAGAC CCTAAGTGTC 
AAGGTGATGA GAGATCCCAA TGGGAAATCC AAAGGCTTTG GCTTTGTGAG TTACGAAAAA 
CACGAGGATG CCAATAAGGC TGTGGAAGAG ATGAATGGAA AAGAAATAAG TGGTAAAATC 
ATATTTGTAG GCCGTGCACA AAAGAAAGTA GAACGGCAGG CAGAGTTAAA ACGGAAATTT 
GAACAGTTGA AACAGGAGAG AATTAGTCGA TATCAGGGGG TGAATCTCTA CATTAAGAAC 
TTGGATGACA CTATTGATGA TGAGAAATTA AGGAAAGAAT TTTCTCCTTT TGGATCAATT 
ACCAGTGCTA AGGTAATGCT GGAGGATGGA AGAAGCAAAG GGTTTGGCTT CGTCTGCTTC 
TCATCTCCTG AAGAAGCAAC CAAAGCAGTC ACTGAGATGA ATGGACGCAT TGTGGGCTCC 
AAGCCACTAT ATGTTGCCCT GGCCCAGAGG AAGGAAGAGA GAAAGGCTCA CCTGACCAAC 
CAGTATATGC AACGAGTGGC TGGAATGAGA GCACTTCCTG CCAATGCCAT CTTAAATCAG 
TTCCAGCCTG CAGCGGGTGG CTACTTTGTG CCAGCAGTCC CACAGGCTCA GGGAAGGCCT 
CCATATTATA CACCTAACCA GTTAGCACAG ATGAGGCCTA ATCCACGCTG GCAGCAAGGT 
GGGAGACCTC AAGGCTTCCA AGGAATGCCA AGTGCTATAC GCCAGTCTGG GCCTCGTCCA 
ACTCTTCGCC ATCTGGCTCC AACTGGTAAT GCTCCGGCCT CTCGTGGCCT CCCTACTACC 
ACTCAGAGAG TCGGGTCTGA GTGCCCGGAC CGCTTGGCTA TGGACTTTGG TGGGGCTGGT 
GCCGCCCAGC AAGGGCTGAC TGACAGCTGC CAGTCTGGAG GCGTTCCCAC AGCTGTGCAG 
AACTTAGCGC CACGCGCTGC TGTTGCTGCT GCTGCTCCCC GGGCTGTTGC CCCCTACAAA 
TACGCCTCCA GTGTCCGCAG CCCTCATCCT GCCATACAGC CTCTGCAGGC ACCCCAGCCT 
GCGGTCCATG TGCAGGGGCA GGAGCCACTG ACTGCCTCCA TGCTGGCTGC AGCACCCCCC 
CAGGAACAGA AGCAGATGCT GGGAGAACGC TTGTTCCCAC TCATCCAAAC AATGCATTCA 
AATCTGGCTG GGAAGATCAC GGGAATGCTG CTGGAGATAG ACAACTCTGA GCTGCTGCAC 
ATGTTAGAGT CCCCCGAGTC TCTCCGCTCC AAGGTGGATG AAGCTGTAGC AGTTCTACAG 
GCTCATCATG CCAAGAAAGA AGCTGCCCAG AAGGTGGGCG CTGTTGCTGC TGCTACCTCT 
TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PABPC4 ( NM_001135653.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001129125.1 Homo sapiens poly(A) binding protein cytoplasmic 4 (PABPC4), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu24716
Clone ID Related Accession (Same CDS sequence)	NM_001135653.2 , NM_001135653.1
Accession Version	NM_001135653.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1983bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-01
Organism	Homo sapiens(human)
Product	polyadenylate-binding protein 4 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DB455681.1, BC094755.1 and BC029969.1. Transcript Variant: This variant (1) encodes the longest isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC029969.1, BC094755.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1966682, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAACGCTG CGGCCAGCAG CTACCCCATG GCCTCCCTGT ACGTGGGCGA CCTGCATTCG 
GACGTCACCG AGGCCATGCT GTACGAAAAG TTCAGCCCCG CGGGGCCTGT GCTGTCCATC 
CGGGTCTGCC GCGATATGAT CACCCGCCGC TCCCTGGGCT ATGCCTACGT CAACTTCCAG 
CAGCCGGCCG ACGCTGAGCG GGCTTTGGAC ACCATGAACT TTGATGTGAT TAAGGGAAAG 
CCAATCCGCA TCATGTGGTC TCAGAGGGAT CCCTCTTTGA GAAAATCTGG TGTGGGAAAC 
GTCTTCATCA AGAACCTGGA CAAATCTATA GATAACAAGG CACTTTATGA TACTTTTTCT 
GCTTTTGGAA ACATACTGTC CTGCAAGGTG GTGTGTGATG AGAACGGCTC TAAGGGTTAT 
GCCTTTGTCC ACTTCGAGAC CCAAGAGGCT GCCGACAAGG CCATCGAGAA GATGAATGGC 
ATGCTCCTCA ATGACCGCAA AGTATTTGTG GGCAGATTCA AGTCTCGCAA AGAGCGGGAA 
GCTGAGCTTG GAGCCAAAGC CAAGGAATTC ACCAATGTTT ATATCAAAAA CTTTGGGGAA 
GAGGTGGATG ATGAGAGTCT GAAAGAGCTA TTCAGTCAGT TTGGTAAGAC CCTAAGTGTC 
AAGGTGATGA GAGATCCCAA TGGGAAATCC AAAGGCTTTG GCTTTGTGAG TTACGAAAAA 
CACGAGGATG CCAATAAGGC TGTGGAAGAG ATGAATGGAA AAGAAATAAG TGGTAAAATC 
ATATTTGTAG GCCGTGCACA AAAGAAAGTA GAACGGCAGG CAGAGTTAAA ACGGAAATTT 
GAACAGTTGA AACAGGAGAG AATTAGTCGA TATCAGGGGG TGAATCTCTA CATTAAGAAC 
TTGGATGACA CTATTGATGA TGAGAAATTA AGGAAAGAAT TTTCTCCTTT TGGATCAATT 
ACCAGTGCTA AGGTAATGCT GGAGGATGGA AGAAGCAAAG GGTTTGGCTT CGTCTGCTTC 
TCATCTCCTG AAGAAGCAAC CAAAGCAGTC ACTGAGATGA ATGGACGCAT TGTGGGCTCC 
AAGCCACTAT ATGTTGCCCT GGCCCAGAGG AAGGAAGAGA GAAAGGCTCA CCTGACCAAC 
CAGTATATGC AACGAGTGGC TGGAATGAGA GCACTTCCTG CCAATGCCAT CTTAAATCAG 
TTCCAGCCTG CAGCGGGTGG CTACTTTGTG CCAGCAGTCC CACAGGCTCA GGGAAGGCCT 
CCATATTATA CACCTAACCA GTTAGCACAG ATGAGGCCTA ATCCACGCTG GCAGCAAGGT 
GGGAGACCTC AAGGCTTCCA AGGAATGCCA AGTGCTATAC GCCAGTCTGG GCCTCGTCCA 
ACTCTTCGCC ATCTGGCTCC AACTGGTAAT GCTCCGGCCT CTCGTGGCCT CCCTACTACC 
ACTCAGAGAG TCGGGTCTGA GTGCCCGGAC CGCTTGGCTA TGGACTTTGG TGGGGCTGGT 
GCCGCCCAGC AAGGGCTGAC TGACAGCTGC CAGTCTGGAG GCGTTCCCAC AGCTGTGCAG 
AACTTAGCGC CACGCGCTGC TGTTGCTGCT GCTGCTCCCC GGGCTGTTGC CCCCTACAAA 
TACGCCTCCA GTGTCCGCAG CCCTCATCCT GCCATACAGC CTCTGCAGGC ACCCCAGCCT 
GCGGTCCATG TGCAGGGGCA GGAGCCACTG ACTGCCTCCA TGCTGGCTGC AGCACCCCCC 
CAGGAACAGA AGCAGATGCT GGGAGAACGC TTGTTCCCAC TCATCCAAAC AATGCATTCA 
AATCTGGCTG GGAAGATCAC GGGAATGCTG CTGGAGATAG ACAACTCTGA GCTGCTGCAC 
ATGTTAGAGT CCCCCGAGTC TCTCCGCTCC AAGGTGGATG AAGCTGTAGC AGTTCTACAG 
GCTCATCATG CCAAGAAAGA AGCTGCCCAG AAGGTGGGCG CTGTTGCTGC TGCTACCTCT 
TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001129125.1
CDS	899..2881
Translation	MNAAASSYPMASLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALDTMNFDVIKGKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDENGSKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFKSRKEREAELGAKAKEFTNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPNGKSKGFGFVSYEKHEDANKAVEEMNGKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVNLYIKNLDDTIDDEKLRKEFSPFGSITSAKVMLEDGRSKGFGFVCFSSPEEATKAVTEMNGRIVGSKPLYVALAQRKEERKAHLTNQYMQRVAGMRALPANAILNQFQPAAGGYFVPAVPQAQGRPPYYTPNQLAQMRPNPRWQQGGRPQGFQGMPSAIRQSGPRPTLRHLAPTGNAPASRGLPTTTQRVGSECPDRLAMDFGGAGAAQQGLTDSCQSGGVPTAVQNLAPRAAVAAAAPRAVAPYKYASSVRSPHPAIQPLQAPQPAVHVQGQEPLTASMLAAAPPQEQKQMLGERLFPLIQTMHSNLAGKITGMLLEIDNSELLHMLESPESLRSKVDEAVAVLQAHHAKKEAAQKVGAVAAATS

Target ORF information:

RefSeq Version	NM_001135653.1
Organism	Homo sapiens(human)
Definition	Homo sapiens poly(A) binding protein cytoplasmic 4 (PABPC4), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001135653.1

ORF Insert Sequence:

ATGAACGCTG CGGCCAGCAG CTACCCCATG GCCTCCCTGT ACGTGGGCGA CCTGCATTCG 
GACGTCACCG AGGCCATGCT GTACGAAAAG TTCAGCCCCG CGGGGCCTGT GCTGTCCATC 
CGGGTCTGCC GCGATATGAT CACCCGCCGC TCCCTGGGCT ATGCCTACGT CAACTTCCAG 
CAGCCGGCCG ACGCTGAGCG GGCTTTGGAC ACCATGAACT TTGATGTGAT TAAGGGAAAG 
CCAATCCGCA TCATGTGGTC TCAGAGGGAT CCCTCTTTGA GAAAATCTGG TGTGGGAAAC 
GTCTTCATCA AGAACCTGGA CAAATCTATA GATAACAAGG CACTTTATGA TACTTTTTCT 
GCTTTTGGAA ACATACTGTC CTGCAAGGTG GTGTGTGATG AGAACGGCTC TAAGGGTTAT 
GCCTTTGTCC ACTTCGAGAC CCAAGAGGCT GCCGACAAGG CCATCGAGAA GATGAATGGC 
ATGCTCCTCA ATGACCGCAA AGTATTTGTG GGCAGATTCA AGTCTCGCAA AGAGCGGGAA 
GCTGAGCTTG GAGCCAAAGC CAAGGAATTC ACCAATGTTT ATATCAAAAA CTTTGGGGAA 
GAGGTGGATG ATGAGAGTCT GAAAGAGCTA TTCAGTCAGT TTGGTAAGAC CCTAAGTGTC 
AAGGTGATGA GAGATCCCAA TGGGAAATCC AAAGGCTTTG GCTTTGTGAG TTACGAAAAA 
CACGAGGATG CCAATAAGGC TGTGGAAGAG ATGAATGGAA AAGAAATAAG TGGTAAAATC 
ATATTTGTAG GCCGTGCACA AAAGAAAGTA GAACGGCAGG CAGAGTTAAA ACGGAAATTT 
GAACAGTTGA AACAGGAGAG AATTAGTCGA TATCAGGGGG TGAATCTCTA CATTAAGAAC 
TTGGATGACA CTATTGATGA TGAGAAATTA AGGAAAGAAT TTTCTCCTTT TGGATCAATT 
ACCAGTGCTA AGGTAATGCT GGAGGATGGA AGAAGCAAAG GGTTTGGCTT CGTCTGCTTC 
TCATCTCCTG AAGAAGCAAC CAAAGCAGTC ACTGAGATGA ATGGACGCAT TGTGGGCTCC 
AAGCCACTAT ATGTTGCCCT GGCCCAGAGG AAGGAAGAGA GAAAGGCTCA CCTGACCAAC 
CAGTATATGC AACGAGTGGC TGGAATGAGA GCACTTCCTG CCAATGCCAT CTTAAATCAG 
TTCCAGCCTG CAGCGGGTGG CTACTTTGTG CCAGCAGTCC CACAGGCTCA GGGAAGGCCT 
CCATATTATA CACCTAACCA GTTAGCACAG ATGAGGCCTA ATCCACGCTG GCAGCAAGGT 
GGGAGACCTC AAGGCTTCCA AGGAATGCCA AGTGCTATAC GCCAGTCTGG GCCTCGTCCA 
ACTCTTCGCC ATCTGGCTCC AACTGGTAAT GCTCCGGCCT CTCGTGGCCT CCCTACTACC 
ACTCAGAGAG TCGGGTCTGA GTGCCCGGAC CGCTTGGCTA TGGACTTTGG TGGGGCTGGT 
GCCGCCCAGC AAGGGCTGAC TGACAGCTGC CAGTCTGGAG GCGTTCCCAC AGCTGTGCAG 
AACTTAGCGC CACGCGCTGC TGTTGCTGCT GCTGCTCCCC GGGCTGTTGC CCCCTACAAA 
TACGCCTCCA GTGTCCGCAG CCCTCATCCT GCCATACAGC CTCTGCAGGC ACCCCAGCCT 
GCGGTCCATG TGCAGGGGCA GGAGCCACTG ACTGCCTCCA TGCTGGCTGC AGCACCCCCC 
CAGGAACAGA AGCAGATGCT GGGAGAACGC TTGTTCCCAC TCATCCAAAC AATGCATTCA 
AATCTGGCTG GGAAGATCAC GGGAATGCTG CTGGAGATAG ACAACTCTGA GCTGCTGCAC 
ATGTTAGAGT CCCCCGAGTC TCTCCGCTCC AAGGTGGATG AAGCTGTAGC AGTTCTACAG 
GCTCATCATG CCAAGAAAGA AGCTGCCCAG AAGGTGGGCG CTGTTGCTGC TGCTACCTCT 
TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PABPC4 ( NM_003819.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_003810.1 Homo sapiens poly(A) binding protein cytoplasmic 4 (PABPC4), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu24792
Clone ID Related Accession (Same CDS sequence)	NM_003819.3 , NM_003819.4
Accession Version	NM_003819.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1935bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-20
Organism	Homo sapiens(human)
Product	polyadenylate-binding protein 4 isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DB455681.1, BC094755.1, U33818.1 and BC029969.1. On Oct 3, 2008 this sequence version replaced NM_003819.2. Transcript Variant: This variant (2) lacks an in-frame segment in the coding region, as compared to variant 1. The resulting isoform 2 lacks an internal segment, as compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: U75686.2 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1966682, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAACGCTG CGGCCAGCAG CTACCCCATG GCCTCCCTGT ACGTGGGCGA CCTGCATTCG 
GACGTCACCG AGGCCATGCT GTACGAAAAG TTCAGCCCCG CGGGGCCTGT GCTGTCCATC 
CGGGTCTGCC GCGATATGAT CACCCGCCGC TCCCTGGGCT ATGCCTACGT CAACTTCCAG 
CAGCCGGCCG ACGCTGAGCG GGCTTTGGAC ACCATGAACT TTGATGTGAT TAAGGGAAAG 
CCAATCCGCA TCATGTGGTC TCAGAGGGAT CCCTCTTTGA GAAAATCTGG TGTGGGAAAC 
GTCTTCATCA AGAACCTGGA CAAATCTATA GATAACAAGG CACTTTATGA TACTTTTTCT 
GCTTTTGGAA ACATACTGTC CTGCAAGGTG GTGTGTGATG AGAACGGCTC TAAGGGTTAT 
GCCTTTGTCC ACTTCGAGAC CCAAGAGGCT GCCGACAAGG CCATCGAGAA GATGAATGGC 
ATGCTCCTCA ATGACCGCAA AGTATTTGTG GGCAGATTCA AGTCTCGCAA AGAGCGGGAA 
GCTGAGCTTG GAGCCAAAGC CAAGGAATTC ACCAATGTTT ATATCAAAAA CTTTGGGGAA 
GAGGTGGATG ATGAGAGTCT GAAAGAGCTA TTCAGTCAGT TTGGTAAGAC CCTAAGTGTC 
AAGGTGATGA GAGATCCCAA TGGGAAATCC AAAGGCTTTG GCTTTGTGAG TTACGAAAAA 
CACGAGGATG CCAATAAGGC TGTGGAAGAG ATGAATGGAA AAGAAATAAG TGGTAAAATC 
ATATTTGTAG GCCGTGCACA AAAGAAAGTA GAACGGCAGG CAGAGTTAAA ACGGAAATTT 
GAACAGTTGA AACAGGAGAG AATTAGTCGA TATCAGGGGG TGAATCTCTA CATTAAGAAC 
TTGGATGACA CTATTGATGA TGAGAAATTA AGGAAAGAAT TTTCTCCTTT TGGATCAATT 
ACCAGTGCTA AGGTAATGCT GGAGGATGGA AGAAGCAAAG GGTTTGGCTT CGTCTGCTTC 
TCATCTCCTG AAGAAGCAAC CAAAGCAGTC ACTGAGATGA ATGGACGCAT TGTGGGCTCC 
AAGCCACTAT ATGTTGCCCT GGCCCAGAGG AAGGAAGAGA GAAAGGCTCA CCTGACCAAC 
CAGTATATGC AACGAGTGGC TGGAATGAGA GCACTTCCTG CCAATGCCAT CTTAAATCAG 
TTCCAGCCTG CAGCGGGTGG CTACTTTGTG CCAGCAGTCC CACAGGCTCA GGGAAGGCCT 
CCATATTATA CACCTAACCA GTTAGCACAG ATGAGGCCTA ATCCACGCTG GCAGCAAGGT 
GGGAGACCTC AAGGCTTCCA AGGAATGCCA AGTGCTATAC GCCAGTCTGG GCCTCGTCCA 
ACTCTTCGCC ATCTGGCTCC AACTGGGTCT GAGTGCCCGG ACCGCTTGGC TATGGACTTT 
GGTGGGGCTG GTGCCGCCCA GCAAGGGCTG ACTGACAGCT GCCAGTCTGG AGGCGTTCCC 
ACAGCTGTGC AGAACTTAGC GCCACGCGCT GCTGTTGCTG CTGCTGCTCC CCGGGCTGTT 
GCCCCCTACA AATACGCCTC CAGTGTCCGC AGCCCTCATC CTGCCATACA GCCTCTGCAG 
GCACCCCAGC CTGCGGTCCA TGTGCAGGGG CAGGAGCCAC TGACTGCCTC CATGCTGGCT 
GCAGCACCCC CCCAGGAACA GAAGCAGATG CTGGGAGAAC GCTTGTTCCC ACTCATCCAA 
ACAATGCATT CAAATCTGGC TGGGAAGATC ACGGGAATGC TGCTGGAGAT AGACAACTCT 
GAGCTGCTGC ACATGTTAGA GTCCCCCGAG TCTCTCCGCT CCAAGGTGGA TGAAGCTGTA 
GCAGTTCTAC AGGCTCATCA TGCCAAGAAA GAAGCTGCCC AGAAGGTGGG CGCTGTTGCT 
GCTGCTACCT CTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_003810.1
CDS	899..2833
Translation	MNAAASSYPMASLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALDTMNFDVIKGKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDENGSKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFKSRKEREAELGAKAKEFTNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPNGKSKGFGFVSYEKHEDANKAVEEMNGKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVNLYIKNLDDTIDDEKLRKEFSPFGSITSAKVMLEDGRSKGFGFVCFSSPEEATKAVTEMNGRIVGSKPLYVALAQRKEERKAHLTNQYMQRVAGMRALPANAILNQFQPAAGGYFVPAVPQAQGRPPYYTPNQLAQMRPNPRWQQGGRPQGFQGMPSAIRQSGPRPTLRHLAPTGSECPDRLAMDFGGAGAAQQGLTDSCQSGGVPTAVQNLAPRAAVAAAAPRAVAPYKYASSVRSPHPAIQPLQAPQPAVHVQGQEPLTASMLAAAPPQEQKQMLGERLFPLIQTMHSNLAGKITGMLLEIDNSELLHMLESPESLRSKVDEAVAVLQAHHAKKEAAQKVGAVAAATS

Target ORF information:

RefSeq Version	NM_003819.3
Organism	Homo sapiens(human)
Definition	Homo sapiens poly(A) binding protein cytoplasmic 4 (PABPC4), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_003819.3

ORF Insert Sequence:

ATGAACGCTG CGGCCAGCAG CTACCCCATG GCCTCCCTGT ACGTGGGCGA CCTGCATTCG 
GACGTCACCG AGGCCATGCT GTACGAAAAG TTCAGCCCCG CGGGGCCTGT GCTGTCCATC 
CGGGTCTGCC GCGATATGAT CACCCGCCGC TCCCTGGGCT ATGCCTACGT CAACTTCCAG 
CAGCCGGCCG ACGCTGAGCG GGCTTTGGAC ACCATGAACT TTGATGTGAT TAAGGGAAAG 
CCAATCCGCA TCATGTGGTC TCAGAGGGAT CCCTCTTTGA GAAAATCTGG TGTGGGAAAC 
GTCTTCATCA AGAACCTGGA CAAATCTATA GATAACAAGG CACTTTATGA TACTTTTTCT 
GCTTTTGGAA ACATACTGTC CTGCAAGGTG GTGTGTGATG AGAACGGCTC TAAGGGTTAT 
GCCTTTGTCC ACTTCGAGAC CCAAGAGGCT GCCGACAAGG CCATCGAGAA GATGAATGGC 
ATGCTCCTCA ATGACCGCAA AGTATTTGTG GGCAGATTCA AGTCTCGCAA AGAGCGGGAA 
GCTGAGCTTG GAGCCAAAGC CAAGGAATTC ACCAATGTTT ATATCAAAAA CTTTGGGGAA 
GAGGTGGATG ATGAGAGTCT GAAAGAGCTA TTCAGTCAGT TTGGTAAGAC CCTAAGTGTC 
AAGGTGATGA GAGATCCCAA TGGGAAATCC AAAGGCTTTG GCTTTGTGAG TTACGAAAAA 
CACGAGGATG CCAATAAGGC TGTGGAAGAG ATGAATGGAA AAGAAATAAG TGGTAAAATC 
ATATTTGTAG GCCGTGCACA AAAGAAAGTA GAACGGCAGG CAGAGTTAAA ACGGAAATTT 
GAACAGTTGA AACAGGAGAG AATTAGTCGA TATCAGGGGG TGAATCTCTA CATTAAGAAC 
TTGGATGACA CTATTGATGA TGAGAAATTA AGGAAAGAAT TTTCTCCTTT TGGATCAATT 
ACCAGTGCTA AGGTAATGCT GGAGGATGGA AGAAGCAAAG GGTTTGGCTT CGTCTGCTTC 
TCATCTCCTG AAGAAGCAAC CAAAGCAGTC ACTGAGATGA ATGGACGCAT TGTGGGCTCC 
AAGCCACTAT ATGTTGCCCT GGCCCAGAGG AAGGAAGAGA GAAAGGCTCA CCTGACCAAC 
CAGTATATGC AACGAGTGGC TGGAATGAGA GCACTTCCTG CCAATGCCAT CTTAAATCAG 
TTCCAGCCTG CAGCGGGTGG CTACTTTGTG CCAGCAGTCC CACAGGCTCA GGGAAGGCCT 
CCATATTATA CACCTAACCA GTTAGCACAG ATGAGGCCTA ATCCACGCTG GCAGCAAGGT 
GGGAGACCTC AAGGCTTCCA AGGAATGCCA AGTGCTATAC GCCAGTCTGG GCCTCGTCCA 
ACTCTTCGCC ATCTGGCTCC AACTGGGTCT GAGTGCCCGG ACCGCTTGGC TATGGACTTT 
GGTGGGGCTG GTGCCGCCCA GCAAGGGCTG ACTGACAGCT GCCAGTCTGG AGGCGTTCCC 
ACAGCTGTGC AGAACTTAGC GCCACGCGCT GCTGTTGCTG CTGCTGCTCC CCGGGCTGTT 
GCCCCCTACA AATACGCCTC CAGTGTCCGC AGCCCTCATC CTGCCATACA GCCTCTGCAG 
GCACCCCAGC CTGCGGTCCA TGTGCAGGGG CAGGAGCCAC TGACTGCCTC CATGCTGGCT 
GCAGCACCCC CCCAGGAACA GAAGCAGATG CTGGGAGAAC GCTTGTTCCC ACTCATCCAA 
ACAATGCATT CAAATCTGGC TGGGAAGATC ACGGGAATGC TGCTGGAGAT AGACAACTCT 
GAGCTGCTGC ACATGTTAGA GTCCCCCGAG TCTCTCCGCT CCAAGGTGGA TGAAGCTGTA 
GCAGTTCTAC AGGCTCATCA TGCCAAGAAA GAAGCTGCCC AGAAGGTGGG CGCTGTTGCT 
GCTGCTACCT CTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PABPC4 ( NM_003819.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_003810.1 Homo sapiens poly(A) binding protein cytoplasmic 4 (PABPC4), transcript variant 2, mRNA.

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CloneID	OHu24792
Clone ID Related Accession (Same CDS sequence)	NM_003819.3 , NM_003819.4
Accession Version	NM_003819.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1935bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2020-01-03
Organism	Homo sapiens(human)
Product	polyadenylate-binding protein 4 isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DB455681.1, BC094755.1, U33818.1 and BC029969.1. On Jun 1, 2019 this sequence version replaced NM_003819.3. Transcript Variant: This variant (2) lacks an in-frame segment in the coding region, as compared to variant 1. The resulting isoform 2 lacks an internal segment, as compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: U75686.2, SRR7346977.1126808.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1966682, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAACGCTG CGGCCAGCAG CTACCCCATG GCCTCCCTGT ACGTGGGCGA CCTGCATTCG 
GACGTCACCG AGGCCATGCT GTACGAAAAG TTCAGCCCCG CGGGGCCTGT GCTGTCCATC 
CGGGTCTGCC GCGATATGAT CACCCGCCGC TCCCTGGGCT ATGCCTACGT CAACTTCCAG 
CAGCCGGCCG ACGCTGAGCG GGCTTTGGAC ACCATGAACT TTGATGTGAT TAAGGGAAAG 
CCAATCCGCA TCATGTGGTC TCAGAGGGAT CCCTCTTTGA GAAAATCTGG TGTGGGAAAC 
GTCTTCATCA AGAACCTGGA CAAATCTATA GATAACAAGG CACTTTATGA TACTTTTTCT 
GCTTTTGGAA ACATACTGTC CTGCAAGGTG GTGTGTGATG AGAACGGCTC TAAGGGTTAT 
GCCTTTGTCC ACTTCGAGAC CCAAGAGGCT GCCGACAAGG CCATCGAGAA GATGAATGGC 
ATGCTCCTCA ATGACCGCAA AGTATTTGTG GGCAGATTCA AGTCTCGCAA AGAGCGGGAA 
GCTGAGCTTG GAGCCAAAGC CAAGGAATTC ACCAATGTTT ATATCAAAAA CTTTGGGGAA 
GAGGTGGATG ATGAGAGTCT GAAAGAGCTA TTCAGTCAGT TTGGTAAGAC CCTAAGTGTC 
AAGGTGATGA GAGATCCCAA TGGGAAATCC AAAGGCTTTG GCTTTGTGAG TTACGAAAAA 
CACGAGGATG CCAATAAGGC TGTGGAAGAG ATGAATGGAA AAGAAATAAG TGGTAAAATC 
ATATTTGTAG GCCGTGCACA AAAGAAAGTA GAACGGCAGG CAGAGTTAAA ACGGAAATTT 
GAACAGTTGA AACAGGAGAG AATTAGTCGA TATCAGGGGG TGAATCTCTA CATTAAGAAC 
TTGGATGACA CTATTGATGA TGAGAAATTA AGGAAAGAAT TTTCTCCTTT TGGATCAATT 
ACCAGTGCTA AGGTAATGCT GGAGGATGGA AGAAGCAAAG GGTTTGGCTT CGTCTGCTTC 
TCATCTCCTG AAGAAGCAAC CAAAGCAGTC ACTGAGATGA ATGGACGCAT TGTGGGCTCC 
AAGCCACTAT ATGTTGCCCT GGCCCAGAGG AAGGAAGAGA GAAAGGCTCA CCTGACCAAC 
CAGTATATGC AACGAGTGGC TGGAATGAGA GCACTTCCTG CCAATGCCAT CTTAAATCAG 
TTCCAGCCTG CAGCGGGTGG CTACTTTGTG CCAGCAGTCC CACAGGCTCA GGGAAGGCCT 
CCATATTATA CACCTAACCA GTTAGCACAG ATGAGGCCTA ATCCACGCTG GCAGCAAGGT 
GGGAGACCTC AAGGCTTCCA AGGAATGCCA AGTGCTATAC GCCAGTCTGG GCCTCGTCCA 
ACTCTTCGCC ATCTGGCTCC AACTGGGTCT GAGTGCCCGG ACCGCTTGGC TATGGACTTT 
GGTGGGGCTG GTGCCGCCCA GCAAGGGCTG ACTGACAGCT GCCAGTCTGG AGGCGTTCCC 
ACAGCTGTGC AGAACTTAGC GCCACGCGCT GCTGTTGCTG CTGCTGCTCC CCGGGCTGTT 
GCCCCCTACA AATACGCCTC CAGTGTCCGC AGCCCTCATC CTGCCATACA GCCTCTGCAG 
GCACCCCAGC CTGCGGTCCA TGTGCAGGGG CAGGAGCCAC TGACTGCCTC CATGCTGGCT 
GCAGCACCCC CCCAGGAACA GAAGCAGATG CTGGGAGAAC GCTTGTTCCC ACTCATCCAA 
ACAATGCATT CAAATCTGGC TGGGAAGATC ACGGGAATGC TGCTGGAGAT AGACAACTCT 
GAGCTGCTGC ACATGTTAGA GTCCCCCGAG TCTCTCCGCT CCAAGGTGGA TGAAGCTGTA 
GCAGTTCTAC AGGCTCATCA TGCCAAGAAA GAAGCTGCCC AGAAGGTGGG CGCTGTTGCT 
GCTGCTACCT CTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_003810.1
CDS	840..2774
Translation	MNAAASSYPMASLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALDTMNFDVIKGKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDENGSKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFKSRKEREAELGAKAKEFTNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPNGKSKGFGFVSYEKHEDANKAVEEMNGKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVNLYIKNLDDTIDDEKLRKEFSPFGSITSAKVMLEDGRSKGFGFVCFSSPEEATKAVTEMNGRIVGSKPLYVALAQRKEERKAHLTNQYMQRVAGMRALPANAILNQFQPAAGGYFVPAVPQAQGRPPYYTPNQLAQMRPNPRWQQGGRPQGFQGMPSAIRQSGPRPTLRHLAPTGSECPDRLAMDFGGAGAAQQGLTDSCQSGGVPTAVQNLAPRAAVAAAAPRAVAPYKYASSVRSPHPAIQPLQAPQPAVHVQGQEPLTASMLAAAPPQEQKQMLGERLFPLIQTMHSNLAGKITGMLLEIDNSELLHMLESPESLRSKVDEAVAVLQAHHAKKEAAQKVGAVAAATS

Target ORF information:

RefSeq Version	NM_003819.4
Organism	Homo sapiens(human)
Definition	Homo sapiens poly(A) binding protein cytoplasmic 4 (PABPC4), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_003819.4

ORF Insert Sequence:

ATGAACGCTG CGGCCAGCAG CTACCCCATG GCCTCCCTGT ACGTGGGCGA CCTGCATTCG 
GACGTCACCG AGGCCATGCT GTACGAAAAG TTCAGCCCCG CGGGGCCTGT GCTGTCCATC 
CGGGTCTGCC GCGATATGAT CACCCGCCGC TCCCTGGGCT ATGCCTACGT CAACTTCCAG 
CAGCCGGCCG ACGCTGAGCG GGCTTTGGAC ACCATGAACT TTGATGTGAT TAAGGGAAAG 
CCAATCCGCA TCATGTGGTC TCAGAGGGAT CCCTCTTTGA GAAAATCTGG TGTGGGAAAC 
GTCTTCATCA AGAACCTGGA CAAATCTATA GATAACAAGG CACTTTATGA TACTTTTTCT 
GCTTTTGGAA ACATACTGTC CTGCAAGGTG GTGTGTGATG AGAACGGCTC TAAGGGTTAT 
GCCTTTGTCC ACTTCGAGAC CCAAGAGGCT GCCGACAAGG CCATCGAGAA GATGAATGGC 
ATGCTCCTCA ATGACCGCAA AGTATTTGTG GGCAGATTCA AGTCTCGCAA AGAGCGGGAA 
GCTGAGCTTG GAGCCAAAGC CAAGGAATTC ACCAATGTTT ATATCAAAAA CTTTGGGGAA 
GAGGTGGATG ATGAGAGTCT GAAAGAGCTA TTCAGTCAGT TTGGTAAGAC CCTAAGTGTC 
AAGGTGATGA GAGATCCCAA TGGGAAATCC AAAGGCTTTG GCTTTGTGAG TTACGAAAAA 
CACGAGGATG CCAATAAGGC TGTGGAAGAG ATGAATGGAA AAGAAATAAG TGGTAAAATC 
ATATTTGTAG GCCGTGCACA AAAGAAAGTA GAACGGCAGG CAGAGTTAAA ACGGAAATTT 
GAACAGTTGA AACAGGAGAG AATTAGTCGA TATCAGGGGG TGAATCTCTA CATTAAGAAC 
TTGGATGACA CTATTGATGA TGAGAAATTA AGGAAAGAAT TTTCTCCTTT TGGATCAATT 
ACCAGTGCTA AGGTAATGCT GGAGGATGGA AGAAGCAAAG GGTTTGGCTT CGTCTGCTTC 
TCATCTCCTG AAGAAGCAAC CAAAGCAGTC ACTGAGATGA ATGGACGCAT TGTGGGCTCC 
AAGCCACTAT ATGTTGCCCT GGCCCAGAGG AAGGAAGAGA GAAAGGCTCA CCTGACCAAC 
CAGTATATGC AACGAGTGGC TGGAATGAGA GCACTTCCTG CCAATGCCAT CTTAAATCAG 
TTCCAGCCTG CAGCGGGTGG CTACTTTGTG CCAGCAGTCC CACAGGCTCA GGGAAGGCCT 
CCATATTATA CACCTAACCA GTTAGCACAG ATGAGGCCTA ATCCACGCTG GCAGCAAGGT 
GGGAGACCTC AAGGCTTCCA AGGAATGCCA AGTGCTATAC GCCAGTCTGG GCCTCGTCCA 
ACTCTTCGCC ATCTGGCTCC AACTGGGTCT GAGTGCCCGG ACCGCTTGGC TATGGACTTT 
GGTGGGGCTG GTGCCGCCCA GCAAGGGCTG ACTGACAGCT GCCAGTCTGG AGGCGTTCCC 
ACAGCTGTGC AGAACTTAGC GCCACGCGCT GCTGTTGCTG CTGCTGCTCC CCGGGCTGTT 
GCCCCCTACA AATACGCCTC CAGTGTCCGC AGCCCTCATC CTGCCATACA GCCTCTGCAG 
GCACCCCAGC CTGCGGTCCA TGTGCAGGGG CAGGAGCCAC TGACTGCCTC CATGCTGGCT 
GCAGCACCCC CCCAGGAACA GAAGCAGATG CTGGGAGAAC GCTTGTTCCC ACTCATCCAA 
ACAATGCATT CAAATCTGGC TGGGAAGATC ACGGGAATGC TGCTGGAGAT AGACAACTCT 
GAGCTGCTGC ACATGTTAGA GTCCCCCGAG TCTCTCCGCT CCAAGGTGGA TGAAGCTGTA 
GCAGTTCTAC AGGCTCATCA TGCCAAGAAA GAAGCTGCCC AGAAGGTGGG CGCTGTTGCT 
GCTGCTACCT CTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Identification of a Nuclear Exosome Decay Pathway for Processed Transcripts.
Molecular cell64(3)520-533(2016 Nov)
Meola N,Domanski M,Karadoulama E,Chen Y,Gentil C,Pultz D,Vitting-Seerup K,Lykke-Andersen S,Andersen JS,Sandelin A,Jensen TH

Gender-specific association between the cytoplasmic poly(A) binding protein 4 rs4660293 single nucleotide polymorphism and serum lipid levels.
Molecular medicine reports12(3)3476-86(2015 Sep)
Wu J,Yin RX,Guo T,Lin QZ,Shen SW,Sun JQ,Shi GY,Wu JZ,Yang DZ,Lin WX

Discovery and refinement of loci associated with lipid levels.
Nature genetics45(11)1274-1283(2013 Nov)
Willer CJ,Schmidt EM,Sengupta S,Peloso GM,Gustafsson S,Kanoni S,Ganna A,Chen J,Buchkovich ML,Mora S,Beckmann JS,Bragg-Gresham JL,Chang HY,Demirkan A,Den Hertog HM,Do R,Donnelly LA,Ehret GB,Esko T,Feitosa MF,Ferreira T,Fischer K,Fontanillas P,Fraser RM,Freitag DF,Gurdasani D,Heikkil? K,Hypp?nen E,Isaacs A,Jackson AU,Johansson ?,Johnson T,Kaakinen M,Kettunen J,Kleber ME,Li X,Luan J,Lyytik?inen LP,Magnusson PKE,Mangino M,Mihailov E,Montasser ME,M?ller-Nurasyid M,Nolte IM,O'Connell JR,Palmer CD,Perola M,Petersen AK,Sanna S,Saxena R,Service SK,Shah S,Shungin D,Sidore C,Song C,Strawbridge RJ,Surakka I,Tanaka T,Teslovich TM,Thorleifsson G,Van den Herik EG,Voight BF,Volcik KA,Waite LL,Wong A,Wu Y,Zhang W,Absher D,Asiki G,Barroso I,Been LF,Bolton JL,Bonnycastle LL,Brambilla P,Burnett MS,Cesana G,Dimitriou M,Doney ASF,D?ring A,Elliott P,Epstein SE,Ingi Eyjolfsson G,Gigante B,Goodarzi MO,Grallert H,Gravito ML,Groves CJ,Hallmans G,Hartikainen AL,Hayward C,Hernandez D,Hicks AA,Holm H,Hung YJ,Illig T,Jones MR,Kaleebu P,Kastelein JJP,Khaw KT,Kim E,Klopp N,Komulainen P,Kumari M,Langenberg C,Lehtim?ki T,Lin SY,Lindstr?m J,Loos RJF,Mach F,McArdle WL,Meisinger C,Mitchell BD,M?ller G,Nagaraja R,Narisu N,Nieminen TVM,Nsubuga RN,Olafsson I,Ong KK,Palotie A,Papamarkou T,Pomilla C,Pouta A,Rader DJ,Reilly MP,Ridker PM,Rivadeneira F,Rudan I,Ruokonen A,Samani N,Scharnagl H,Seeley J,Silander K,Stan??kov? A,Stirrups K,Swift AJ,Tiret L,Uitterlinden AG,van Pelt LJ,Vedantam S,Wainwright N,Wijmenga C,Wild SH,Willemsen G,Wilsgaard T,Wilson JF,Young EH,Zhao JH,Adair LS,Arveiler D,Assimes TL,Bandinelli S,Bennett F,Bochud M,Boehm BO,Boomsma DI,Borecki IB,Bornstein SR,Bovet P,Burnier M,Campbell H,Chakravarti A,Chambers JC,Chen YI,Collins FS,Cooper RS,Danesh J,Dedoussis G,de Faire U,Feranil AB,Ferri?res J,Ferrucci L,Freimer NB,Gieger C,Groop LC,Gudnason V,Gyllensten U,Hamsten A,Harris TB,Hingorani A,Hirschhorn JN,Hofman A,Hovingh GK,Hsiung CA,Humphries SE,Hunt SC,Hveem K,Iribarren C,J?rvelin MR,Jula A,K?h?nen M,Kaprio J,Kes?niemi A,Kivimaki M,Kooner JS,Koudstaal PJ,Krauss RM,Kuh D,Kuusisto J,Kyvik KO,Laakso M,Lakka TA,Lind L,Lindgren CM,Martin NG,M?rz W,McCarthy MI,McKenzie CA,Meneton P,Metspalu A,Moilanen L,Morris AD,Munroe PB,Nj?lstad I,Pedersen NL,Power C,Pramstaller PP,Price JF,Psaty BM,Quertermous T,Rauramaa R,Saleheen D,Salomaa V,Sanghera DK,Saramies J,Schwarz PEH,Sheu WH,Shuldiner AR,Siegbahn A,Spector TD,Stefansson K,Strachan DP,Tayo BO,Tremoli E,Tuomilehto J,Uusitupa M,van Duijn CM,Vollenweider P,Wallentin L,Wareham NJ,Whitfield JB,Wolffenbuttel BHR,Ordovas JM,Boerwinkle E,Palmer CNA,Thorsteinsdottir U,Chasman DI,Rotter JI,Franks PW,Ripatti S,Cupples LA,Sandhu MS,Rich SS,Boehnke M,Deloukas P,Kathiresan S,Mohlke KL,Ingelsson E,Abecasis GR,

Cytoplasmic poly(A) binding protein 4 is highly expressed in human colorectal cancer and correlates with better prognosis.
Journal of genetics and genomics = Yi chuan xue bao39(8)369-74(2012 Aug)
Liu D,Yin B,Wang Q,Ju W,Chen Y,Qiu H,Li J,Peng X,Lu C

Depletion of nuclear poly(A) binding protein PABPN1 produces a compensatory response by cytoplasmic PABP4 and PABP5 in cultured human cells.
PloS one7(12)e53036(2012)
Bhattacharjee RB,Bag J

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PABPC4 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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