ADAM19 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	ADAM19
Entrez Gene ID	8728
Full Name	ADAM metallopeptidase domain 19
Synonyms	FKSG34,MADDAM,MLTNB
General protein information	Preferred Names ADAM metallopeptidase domain 19 Names disintegrin and metalloproteinase domain-containing protein 19 ADAM 19 a disintegrin and metalloproteinase domain 19 (meltrin beta) meltrin-beta metalloprotease and disintegrin dendritic antigen marker metalloprotease-disintegrin meltrin beta
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 5 Map Location: 5q33.3
Summary	This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This member is a type I transmembrane protein and serves as a marker for dendritic cell differentiation. It has been demonstrated to be an active metalloproteinase, which may be involved in normal physiological processes such as cell migration, cell adhesion, cell-cell and cell-matrix interactions, and signal transduction. It is proposed to play a role in pathological processes, such as cancer, inflammatory diseases, renal diseases, and Alzheimer's disease. [provided by RefSeq, May 2013].
Disorder MIM:	603640

mRNA and Protein(s)

mRNA	Protein	Name
XM_011534682.2	XP_011532984.1	disintegrin and metalloproteinase domain-containing protein 19 isoform X2
NM_033274.5	NP_150377.1	disintegrin and metalloproteinase domain-containing protein 19 preproprotein
XM_005266003.2	XP_005266060.1	disintegrin and metalloproteinase domain-containing protein 19 isoform X1
NM_033274.4	NP_150377.1	disintegrin and metalloproteinase domain-containing protein 19 preproprotein
XM_017010009.1	XP_016865498.1	disintegrin and metalloproteinase domain-containing protein 19 isoform X2

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	ADAM19	XP_001137856.1
Homo sapiens (human)	ADAM19	NP_150377.1
	ADAM19	XP_001105246.2
Mus musculus (house mouse)	Adam19	NP_033746.1
Rattus norvegicus (Norway rat)	Adam19	NP_001153700.1
Gallus gallus (chicken)	ADAM19	NP_001182051.1
Danio rerio (zebrafish)	LOC571252	XP_699915.6
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP003498	XP_309659.5
Bos taurus (cattle)	ADAM19	NP_001068943.2
Drosophila melanogaster (fruit fly)	Meltrin	NP_001027575.1
Xenopus tropicalis (tropical clawed frog)	adam19	NP_001035105.1
Canis lupus familiaris (dog)	ADAM19	XP_005619308.1

Gene Ontology
Bibliography

Related articles in PubMed

Proteomic characterization of human multiple myeloma bone marrow extracellular matrix.
Glavey SV, Naba A, Manier S, Clauser K, Tahri S, Park J, Reagan MR, Moschetta M, Mishima Y, Gambella M, Rocci A, Sacco A, O'Dwyer ME, Asara JM, Palumbo A, Roccaro AM, Hynes RO, Ghobrial IM
Leukemia31(11)2426-2434(2017 Nov)

Genetic Variants in IL6R and ADAM19 are Associated with COPD Severity in a Mexican Mestizo Population.
P?rez-Rubio G, Silva-Zolezzi I, Fern?ndez-L?pez JC, Camarena ?, Vel?zquez-Uncal M, Morales-Mandujano F, Hern?ndez-Zenteno Rde J, Flores-Trujillo F, S?nchez-Romero C, Vel?zquez-Montero A, Espinosa de Los Monteros C, Sansores RH, Ram?rez-Venegas A, Falf?n-Valencia R
COPD13(5)610-5(2016 Oct)

Genetic and cellular studies highlight that A Disintegrin and Metalloproteinase 19 is a protective biomarker in human prostate cancer.
Hoyne G, Rudnicka C, Sang QX, Roycik M, Howarth S, Leedman P, Schlaich M, Candy P, Matthews V
BMC cancer16151(2016 Feb)

MiR-145 suppressed human retinoblastoma cell proliferation and invasion by targeting ADAM19.
Sun Z, Zhang A, Jiang T, Du Z, Che C, Wang F
International journal of clinical and experimental pathology8(11)14521-7(2015)

Extracellular signal-regulated kinase phosphorylates tumor necrosis factor alpha-converting enzyme at threonine 735: a potential role in regulated shedding.
D?az-Rodr?guez E, Montero JC, Espar?s-Ogando A, Yuste L, Pandiella A
Molecular biology of the cell13(6)2031-44(2002 Jun)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

3 SNPs (rs4329505 and rs4845626 in interleukin 6 receptor [IL6R] and rs1422794 in a disintegrin and metalloproteinase domain 19 [ADAM19]) were associated with a lower risk of suffering the most severe stages of the disease.
Title: Genetic Variants in IL6R and ADAM19 are Associated with COPD Severity in a Mexican Mestizo Population.

ADAM19 is a protective factor for human prostate cancer. Further, this study suggests that upregulation of ADAM19 expression could be of therapeutic potential in human prostate cancer.
Title: Genetic and cellular studies highlight that A Disintegrin and Metalloproteinase 19 is a protective biomarker in human prostate cancer.

MiR-153 has a role in inhibiting migration and invasion of human non-small-cell lung cancer by targeting ADAM19
Title: MiR-153 inhibits migration and invasion of human non-small-cell lung cancer by targeting ADAM19.

miR-30c inhibited colon cancer cells via targeting ADAM19.
Title: Role of microRNA-30c targeting ADAM19 in colorectal cancer.

these findings suggested that miR-145 functions as a tumor suppressor in RB by directly targeting ADAM19 in retinoblastoma cells
Title: MiR-145 suppressed human retinoblastoma cell proliferation and invasion by targeting ADAM19.

The following ADAM19 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the ADAM19 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu00084	NM_033274.5 Latest version!	Homo sapiens ADAM metallopeptidase domain 19 (ADAM19), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$339.50-$475.30 $679.00
OHu62150	XM_011534682.2 Latest version!	Homo sapiens ADAM metallopeptidase domain 19 (ADAM19), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
OHu62150	XM_017010009.1 Latest version!	Homo sapiens ADAM metallopeptidase domain 19 (ADAM19), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
OHu40078	XM_005266003.2 Latest version!	Homo sapiens ADAM metallopeptidase domain 19 (ADAM19), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$475.30 $679.00
View Old Accession Versions >>
OHu00084	NM_033274.4	Homo sapiens ADAM metallopeptidase domain 19 (ADAM19), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$643.30 $919.00
Hide Old Accession Versions >>

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***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

ADAM19 ( NM_033274.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_150377.1 Homo sapiens ADAM metallopeptidase domain 19 (ADAM19), mRNA.

Price & Availability↑

CloneID	OHu00084
Clone ID Related Accession (Same CDS sequence)	NM_033274.5 , NM_033274.4
Accession Version	NM_033274.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2757bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-03
Organism	Homo sapiens(human)
Product	disintegrin and metalloproteinase domain-containing protein 19 preproprotein
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK308182.1, AF311317.1, AC008676.6 and BC024214.2. This sequence is a reference standard in the RefSeqGene project. On Jun 2, 2019 this sequence version replaced NM_033274.4. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: Y13786.2, SRR1803613.164608.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on manual assertion, conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGCCAGGGG GCGCAGGCGC CGCCCGGCTC TGCTTGCTGG CGTTTGCCCT GCAGCCCCTC 
CGGCCGCGGG CGGCGCGGGA GCCTGGATGG ACAAGAGGAA GTGAGGAAGG CAGCCCCAAG 
CTGCAGCATG AACTTATCAT ACCTCAGTGG AAGACTTCAG AAAGCCCCGT GAGAGAAAAG 
CATCCACTCA AAGCTGAGCT CAGGGTAATG GCTGAGGGGC GAGAACTGAT CCTGGACCTG 
GAGAAGAATG AGCAACTTTT TGCTCCTTCC TACACAGAAA CCCATTATAC TTCAAGTGGT 
AACCCTCAAA CCACCACACG GAAATTGGAG GATCACTGCT TTTACCACGG CACGGTGAGG 
GAGACAGAAC TGTCCAGCGT CACGCTCAGC ACTTGCCGAG GAATTAGAGG ACTGATTACG 
GTGAGCAGCA ACCTCAGCTA CGTCATCGAG CCCCTCCCTG ACAGCAAGGG CCAACACCTT 
ATTTACAGAT CTGAACATCT CAAGCCGCCC CCGGGAAACT GTGGGTTCGA GCACTCCAAG 
CCCACCACCA GGGACTGGGC TCTTCAGTTT ACACAACAGA CCAAGAAGCG ACCTCGCAGG 
ATGAAAAGGG AAGATTTAAA CTCCATGAAG TATGTGGAGC TTTACCTCGT GGCTGATTAT 
TTAGAGTTTC AGAAGAATCG ACGAGACCAG GACGCCACCA AACACAAGCT CATAGAGATC 
GCCAACTATG TTGATAAGTT TTACCGATCC TTGAACATCC GGATTGCTCT CGTGGGCTTG 
GAAGTGTGGA CCCACGGGAA CATGTGTGAA GTTTCAGAGA ATCCATATTC TACCCTCTGG 
TCCTTTCTCA GTTGGAGGCG CAAGCTGCTT GCCCAGAAGT ACCATGACAA CGCCCAATTA 
ATCACGGGCA TGTCCTTCCA CGGCACCACC ATCGGCCTGG CCCCCCTCAT GGCCATGTGC 
TCTGTGTACC AGTCTGGAGG AGTCAACATG GACCACTCCG AGAATGCCAT TGGCGTGGCT 
GCCACCATGG CCCACGAGAT GGGCCACAAC TTTGGCATGA CCCATGATTC TGCAGATTGC 
TGCTCGGCCA GTGCGGCTGA TGGTGGGTGC ATCATGGCAG CTGCCACTGG GCACCCCTTT 
CCCAAAGTGT TCAATGGATG CAACAGGAGG GAGCTGGACA GGTATCTGCA GTCAGGTGGT 
GGAATGTGTC TCTCCAACAT GCCAGACACC AGGATGTTGT ATGGAGGCCG GAGGTGTGGG 
AACGGGTATC TGGAAGATGG GGAAGAGTGT GACTGTGGAG AAGAAGAGGA ATGTAACAAC 
CCCTGCTGCA ATGCCTCTAA TTGTACCCTG AGGCCGGGGG CGGAGTGTGC TCACGGCTCC 
TGCTGCCACC AGTGTAAGCT GTTGGCTCCT GGGACCCTGT GCCGCGAGCA GGCCAGGCAG 
TGTGACCTCC CGGAGTTCTG TACGGGCAAG TCTCCCCACT GCCCTACCAA CTTCTACCAG 
ATGGATGGTA CCCCCTGTGA GGGCGGCCAG GCCTACTGCT ACAACGGCAT GTGCCTCACC 
TACCAGGAGC AGTGCCAGCA GCTGTGGGGA CCCGGAGCCC GACCTGCCCC TGACCTCTGC 
TTCGAGAAGG TGAATGTGGC AGGAGACACC TTTGGAAACT GTGGAAAGGA CATGAATGGT 
GAACACAGGA AGTGCAACAT GAGAGATGCG AAGTGTGGGA AGATCCAGTG TCAGAGCTCT 
GAGGCCCGGC CCCTGGAGTC CAACGCGGTG CCCATTGACA CCACTATCAT CATGAATGGG 
AGGCAGATCC AGTGCCGGGG CACCCACGTC TACCGAGGTC CTGAGGAGGA GGGTGACATG 
CTGGACCCAG GGCTGGTGAT GACTGGAACC AAGTGTGGCT ACAACCATAT TTGCTTTGAG 
GGGCAGTGCA GGAACACCTC CTTCTTTGAA ACTGAAGGCT GTGGGAAGAA GTGCAATGGC 
CATGGGGTCT GTAACAACAA CCAGAACTGC CACTGCCTGC CGGGCTGGGC CCCGCCCTTC 
TGCAACACAC CGGGCCACGG GGGCAGTATC GACAGTGGGC CTATGCCCCC TGAGAGTGTG 
GGTCCTGTGG TAGCTGGAGT GTTGGTGGCC ATCTTGGTGC TGGCGGTCCT CATGCTGATG 
TACTACTGCT GCAGACAGAA CAACAAACTA GGCCAACTCA AGCCCTCAGC TCTCCCTTCC 
AAGCTGAGGC AACAGTTCAG TTGTCCCTTC AGGGTTTCTC AGAACAGCGG GACTGGTCAT 
GCCAACCCAA CTTTCAAGCT GCAGACGCCC CAGGGCAAGC GAAAGGTGAT CAACACTCCG 
GAAATCCTGC GGAAGCCCTC CCAGCCTCCT CCCCGGCCCC CTCCAGATTA TCTGCGTGGT 
GGGTCCCCAC CTGCACCACT GCCAGCTCAC CTGAGCAGGG CTGCTAGGAA CTCCCCAGGG 
CCCGGGTCTC AAATAGAGAG GACGGAGTCG TCCAGGAGGC CTCCTCCAAG CCGGCCAATT 
CCCCCCGCAC CAAATTGCAT CGTTTCCCAG GACTTCTCCA GGCCTCGGCC GCCCCAGAAG 
GCACTCCCGG CAAACCCAGT GCCAGGCCGC AGGAGCCTCC CCAGGCCAGG AGGTGCATCC 
CCACTGCGGC CCCCTGGTGC TGGCCCTCAG CAGTCCCGGC CTCTGGCAGC ACTTGCCCCA 
AAGTTTCCAG AATACAGATC ACAGAGGGCT GGAGGGATGA TTAGCTCGAA AATCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_150377.1
CDS	80..2836
Translation	MPGGAGAARLCLLAFALQPLRPRAAREPGWTRGSEEGSPKLQHELIIPQWKTSESPVREKHPLKAELRVMAEGRELILDLEKNEQLFAPSYTETHYTSSGNPQTTTRKLEDHCFYHGTVRETELSSVTLSTCRGIRGLITVSSNLSYVIEPLPDSKGQHLIYRSEHLKPPPGNCGFEHSKPTTRDWALQFTQQTKKRPRRMKREDLNSMKYVELYLVADYLEFQKNRRDQDATKHKLIEIANYVDKFYRSLNIRIALVGLEVWTHGNMCEVSENPYSTLWSFLSWRRKLLAQKYHDNAQLITGMSFHGTTIGLAPLMAMCSVYQSGGVNMDHSENAIGVAATMAHEMGHNFGMTHDSADCCSASAADGGCIMAAATGHPFPKVFNGCNRRELDRYLQSGGGMCLSNMPDTRMLYGGRRCGNGYLEDGEECDCGEEEECNNPCCNASNCTLRPGAECAHGSCCHQCKLLAPGTLCREQARQCDLPEFCTGKSPHCPTNFYQMDGTPCEGGQAYCYNGMCLTYQEQCQQLWGPGARPAPDLCFEKVNVAGDTFGNCGKDMNGEHRKCNMRDAKCGKIQCQSSEARPLESNAVPIDTTIIMNGRQIQCRGTHVYRGPEEEGDMLDPGLVMTGTKCGYNHICFEGQCRNTSFFETEGCGKKCNGHGVCNNNQNCHCLPGWAPPFCNTPGHGGSIDSGPMPPESVGPVVAGVLVAILVLAVLMLMYYCCRQNNKLGQLKPSALPSKLRQQFSCPFRVSQNSGTGHANPTFKLQTPQGKRKVINTPEILRKPSQPPPRPPPDYLRGGSPPAPLPAHLSRAARNSPGPGSQIERTESSRRPPPSRPIPPAPNCIVSQDFSRPRPPQKALPANPVPGRRSLPRPGGASPLRPPGAGPQQSRPLAALAPKFPEYRSQRAGGMISSKI

Target ORF information:

RefSeq Version	NM_033274.5
Organism	Homo sapiens(human)
Definition	Homo sapiens ADAM metallopeptidase domain 19 (ADAM19), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_033274.5

ORF Insert Sequence:

ATGCCAGGGG GCGCAGGCGC CGCCCGGCTC TGCTTGCTGG CGTTTGCCCT GCAGCCCCTC 
CGGCCGCGGG CGGCGCGGGA GCCTGGATGG ACAAGAGGAA GTGAGGAAGG CAGCCCCAAG 
CTGCAGCATG AACTTATCAT ACCTCAGTGG AAGACTTCAG AAAGCCCCGT GAGAGAAAAG 
CATCCACTCA AAGCTGAGCT CAGGGTAATG GCTGAGGGGC GAGAACTGAT CCTGGACCTG 
GAGAAGAATG AGCAACTTTT TGCTCCTTCC TACACAGAAA CCCATTATAC TTCAAGTGGT 
AACCCTCAAA CCACCACACG GAAATTGGAG GATCACTGCT TTTACCACGG CACGGTGAGG 
GAGACAGAAC TGTCCAGCGT CACGCTCAGC ACTTGCCGAG GAATTAGAGG ACTGATTACG 
GTGAGCAGCA ACCTCAGCTA CGTCATCGAG CCCCTCCCTG ACAGCAAGGG CCAACACCTT 
ATTTACAGAT CTGAACATCT CAAGCCGCCC CCGGGAAACT GTGGGTTCGA GCACTCCAAG 
CCCACCACCA GGGACTGGGC TCTTCAGTTT ACACAACAGA CCAAGAAGCG ACCTCGCAGG 
ATGAAAAGGG AAGATTTAAA CTCCATGAAG TATGTGGAGC TTTACCTCGT GGCTGATTAT 
TTAGAGTTTC AGAAGAATCG ACGAGACCAG GACGCCACCA AACACAAGCT CATAGAGATC 
GCCAACTATG TTGATAAGTT TTACCGATCC TTGAACATCC GGATTGCTCT CGTGGGCTTG 
GAAGTGTGGA CCCACGGGAA CATGTGTGAA GTTTCAGAGA ATCCATATTC TACCCTCTGG 
TCCTTTCTCA GTTGGAGGCG CAAGCTGCTT GCCCAGAAGT ACCATGACAA CGCCCAATTA 
ATCACGGGCA TGTCCTTCCA CGGCACCACC ATCGGCCTGG CCCCCCTCAT GGCCATGTGC 
TCTGTGTACC AGTCTGGAGG AGTCAACATG GACCACTCCG AGAATGCCAT TGGCGTGGCT 
GCCACCATGG CCCACGAGAT GGGCCACAAC TTTGGCATGA CCCATGATTC TGCAGATTGC 
TGCTCGGCCA GTGCGGCTGA TGGTGGGTGC ATCATGGCAG CTGCCACTGG GCACCCCTTT 
CCCAAAGTGT TCAATGGATG CAACAGGAGG GAGCTGGACA GGTATCTGCA GTCAGGTGGT 
GGAATGTGTC TCTCCAACAT GCCAGACACC AGGATGTTGT ATGGAGGCCG GAGGTGTGGG 
AACGGGTATC TGGAAGATGG GGAAGAGTGT GACTGTGGAG AAGAAGAGGA ATGTAACAAC 
CCCTGCTGCA ATGCCTCTAA TTGTACCCTG AGGCCGGGGG CGGAGTGTGC TCACGGCTCC 
TGCTGCCACC AGTGTAAGCT GTTGGCTCCT GGGACCCTGT GCCGCGAGCA GGCCAGGCAG 
TGTGACCTCC CGGAGTTCTG TACGGGCAAG TCTCCCCACT GCCCTACCAA CTTCTACCAG 
ATGGATGGTA CCCCCTGTGA GGGCGGCCAG GCCTACTGCT ACAACGGCAT GTGCCTCACC 
TACCAGGAGC AGTGCCAGCA GCTGTGGGGA CCCGGAGCCC GACCTGCCCC TGACCTCTGC 
TTCGAGAAGG TGAATGTGGC AGGAGACACC TTTGGAAACT GTGGAAAGGA CATGAATGGT 
GAACACAGGA AGTGCAACAT GAGAGATGCG AAGTGTGGGA AGATCCAGTG TCAGAGCTCT 
GAGGCCCGGC CCCTGGAGTC CAACGCGGTG CCCATTGACA CCACTATCAT CATGAATGGG 
AGGCAGATCC AGTGCCGGGG CACCCACGTC TACCGAGGTC CTGAGGAGGA GGGTGACATG 
CTGGACCCAG GGCTGGTGAT GACTGGAACC AAGTGTGGCT ACAACCATAT TTGCTTTGAG 
GGGCAGTGCA GGAACACCTC CTTCTTTGAA ACTGAAGGCT GTGGGAAGAA GTGCAATGGC 
CATGGGGTCT GTAACAACAA CCAGAACTGC CACTGCCTGC CGGGCTGGGC CCCGCCCTTC 
TGCAACACAC CGGGCCACGG GGGCAGTATC GACAGTGGGC CTATGCCCCC TGAGAGTGTG 
GGTCCTGTGG TAGCTGGAGT GTTGGTGGCC ATCTTGGTGC TGGCGGTCCT CATGCTGATG 
TACTACTGCT GCAGACAGAA CAACAAACTA GGCCAACTCA AGCCCTCAGC TCTCCCTTCC 
AAGCTGAGGC AACAGTTCAG TTGTCCCTTC AGGGTTTCTC AGAACAGCGG GACTGGTCAT 
GCCAACCCAA CTTTCAAGCT GCAGACGCCC CAGGGCAAGC GAAAGGTGAT CAACACTCCG 
GAAATCCTGC GGAAGCCCTC CCAGCCTCCT CCCCGGCCCC CTCCAGATTA TCTGCGTGGT 
GGGTCCCCAC CTGCACCACT GCCAGCTCAC CTGAGCAGGG CTGCTAGGAA CTCCCCAGGG 
CCCGGGTCTC AAATAGAGAG GACGGAGTCG TCCAGGAGGC CTCCTCCAAG CCGGCCAATT 
CCCCCCGCAC CAAATTGCAT CGTTTCCCAG GACTTCTCCA GGCCTCGGCC GCCCCAGAAG 
GCACTCCCGG CAAACCCAGT GCCAGGCCGC AGGAGCCTCC CCAGGCCAGG AGGTGCATCC 
CCACTGCGGC CCCCTGGTGC TGGCCCTCAG CAGTCCCGGC CTCTGGCAGC ACTTGCCCCA 
AAGTTTCCAG AATACAGATC ACAGAGGGCT GGAGGGATGA TTAGCTCGAA AATCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ADAM19 ( XM_011534682.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011532984.1 Homo sapiens ADAM metallopeptidase domain 19 (ADAM19), transcript variant X3, mRNA.

Price & Availability↑

CloneID	OHu62150
Clone ID Related Accession (Same CDS sequence)	XM_011534682.2 , XM_017010009.1
Accession Version	XM_011534682.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1956bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-03-25
Organism	Homo sapiens(human)
Product	disintegrin and metalloproteinase domain-containing protein 19 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000005.10) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011534682.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Homo sapiens Annotation Release 109 Annotation Version :: 109 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTGTGAAG TTTCAGAGAA TCCATATTCT ACCCTCTGGT CCTTTCTCAG TTGGAGGCGC 
AAGCTGCTTG CCCAGAAGTA CCATGACAAC GCCCAATTAA TCACGGGCAT GTCCTTCCAC 
GGCACCACCA TCGGCCTGGC CCCCCTCATG GCCATGTGCT CTGTGTACCA GTCTGGAGGA 
GTCAACATGG ACCACTCCGA GAATGCCATT GGCGTGGCTG CCACCATGGC CCACGAGATG 
GGCCACAACT TTGGCATGAC CCATGATTCT GCAGATTGCT GCTCGGCCAG TGCGGCTGAT 
GGTGGGTGCA TCATGGCAGC TGCCACTGGG CACCCCTTTC CCAAAGTGTT CAATGGATGC 
AACAGGAGGG AGCTGGACAG GTATCTGCAG TCAGGTGGTG GAATGTGTCT CTCCAACATG 
CCAGACACCA GGATGTTGTA TGGAGGCCGG AGGTGTGGGA ACGGGTATCT GGAAGATGGG 
GAAGAGTGTG ACTGTGGAGA AGAAGAGGAA TGTAACAACC CCTGCTGCAA TGCCTCTAAT 
TGTACCCTGA GGCCGGGGGC GGAGTGTGCT CACGGCTCCT GCTGCCACCA GTGTAAGCTG 
TTGGCTCCTG GGACCCTGTG CCGCGAGCAG GCCAGGCAGT GTGACCTCCC GGAGTTCTGT 
ACGGGCAAGT CTCCCCACTG CCCTACCAAC TTCTACCAGA TGGATGGTAC CCCCTGTGAG 
GGCGGCCAGG CCTACTGCTA CAACGGCATG TGCCTCACCT ACCAGGAGCA GTGCCAGCAG 
CTGTGGGGAC CCGGAGCCCG ACCTGCCCCT GACCTCTGCT TCGAGAAGGT GAATGTGGCA 
GGAGACACCT TTGGAAACTG TGGAAAGGAC ATGAATGGTG AACACAGGAA GTGCAACATG 
AGAGATGCGA AGTGTGGGAA GATCCAGTGT CAGAGCTCTG AGGCCCGGCC CCTGGAGTCC 
AACGCGGTGC CCATTGACAC CACTATCATC ATGAATGGGA GGCAGATCCA GTGCCGGGGC 
ACCCACGTCT ACCGAGGTCC TGAGGAGGAG GGTGACATGC TGGACCCAGG GCTGGTGATG 
ACTGGAACCA AGTGTGGCTA CAACCATATT TGCTTTGAGG GGCAGTGCAG GAACACCTCC 
TTCTTTGAAA CTGAAGGCTG TGGGAAGAAG TGCAATGGCC ATGGGGTCTG TAACAACAAC 
CAGAACTGCC ACTGCCTGCC GGGCTGGGCC CCGCCCTTCT GCAACACACC GGGCCACGGG 
GGCAGTATCG ACAGTGGGCC TATGCCCCCT GAGAGTGTGG GTCCTGTGGT AGCTGGAGTG 
TTGGTGGCCA TCTTGGTGCT GGCGGTCCTC ATGCTGATGT ACTACTGCTG CAGACAGAAC 
AACAAACTAG GCCAACTCAA GCCCTCAGCT CTCCCTTCCA AGCTGAGGCA ACAGTTCAGT 
TGTCCCTTCA GGGTTTCTCA GAACAGCGGG ACTGGTCATG CCAACCCAAC TTTCAAGCTG 
CAGACGCCCC AGGGCAAGCG AAAGGTGATC AACACTCCGG AAATCCTGCG GAAGCCCTCC 
CAGCCTCCTC CCCGGCCCCC TCCAGATTAT CTGCGTGGTG GGTCCCCACC TGCACCACTG 
CCAGCTCACC TGAGCAGGGC TGCTAGGAAC TCCCCAGGGC CCGGGTCTCA AATAGAGAGG 
ACGGAGTCGT CCAGGAGGCC TCCTCCAAGC CGGCCAATTC CCCCCGCACC AAATTGCATC 
GTTTCCCAGG ACTTCTCCAG GCCTCGGCCG CCCCAGAAGG CACTCCCGGC AAACCCAGTG 
CCAGGCCGCA GGAGCCTCCC CAGGCCAGGA GGTGCATCCC CACTGCGGCC CCCTGGTGCT 
GGCCCTCAGC AGTCCCGGCC TCTGGCAGCA CTTGCCCCAA AGTTTCCAGA ATACAGATCA 
CAGAGGGCTG GAGGGATGAT TAGCTCGAAA ATCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011532984.1
CDS	1685..3640
Translation	MCEVSENPYSTLWSFLSWRRKLLAQKYHDNAQLITGMSFHGTTIGLAPLMAMCSVYQSGGVNMDHSENAIGVAATMAHEMGHNFGMTHDSADCCSASAADGGCIMAAATGHPFPKVFNGCNRRELDRYLQSGGGMCLSNMPDTRMLYGGRRCGNGYLEDGEECDCGEEEECNNPCCNASNCTLRPGAECAHGSCCHQCKLLAPGTLCREQARQCDLPEFCTGKSPHCPTNFYQMDGTPCEGGQAYCYNGMCLTYQEQCQQLWGPGARPAPDLCFEKVNVAGDTFGNCGKDMNGEHRKCNMRDAKCGKIQCQSSEARPLESNAVPIDTTIIMNGRQIQCRGTHVYRGPEEEGDMLDPGLVMTGTKCGYNHICFEGQCRNTSFFETEGCGKKCNGHGVCNNNQNCHCLPGWAPPFCNTPGHGGSIDSGPMPPESVGPVVAGVLVAILVLAVLMLMYYCCRQNNKLGQLKPSALPSKLRQQFSCPFRVSQNSGTGHANPTFKLQTPQGKRKVINTPEILRKPSQPPPRPPPDYLRGGSPPAPLPAHLSRAARNSPGPGSQIERTESSRRPPPSRPIPPAPNCIVSQDFSRPRPPQKALPANPVPGRRSLPRPGGASPLRPPGAGPQQSRPLAALAPKFPEYRSQRAGGMISSKI

Target ORF information:

RefSeq Version	XM_011534682.2
Organism	Homo sapiens(human)
Definition	Homo sapiens ADAM metallopeptidase domain 19 (ADAM19), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011534682.2

ORF Insert Sequence:

ATGTGTGAAG TTTCAGAGAA TCCATATTCT ACCCTCTGGT CCTTTCTCAG TTGGAGGCGC 
AAGCTGCTTG CCCAGAAGTA CCATGACAAC GCCCAATTAA TCACGGGCAT GTCCTTCCAC 
GGCACCACCA TCGGCCTGGC CCCCCTCATG GCCATGTGCT CTGTGTACCA GTCTGGAGGA 
GTCAACATGG ACCACTCCGA GAATGCCATT GGCGTGGCTG CCACCATGGC CCACGAGATG 
GGCCACAACT TTGGCATGAC CCATGATTCT GCAGATTGCT GCTCGGCCAG TGCGGCTGAT 
GGTGGGTGCA TCATGGCAGC TGCCACTGGG CACCCCTTTC CCAAAGTGTT CAATGGATGC 
AACAGGAGGG AGCTGGACAG GTATCTGCAG TCAGGTGGTG GAATGTGTCT CTCCAACATG 
CCAGACACCA GGATGTTGTA TGGAGGCCGG AGGTGTGGGA ACGGGTATCT GGAAGATGGG 
GAAGAGTGTG ACTGTGGAGA AGAAGAGGAA TGTAACAACC CCTGCTGCAA TGCCTCTAAT 
TGTACCCTGA GGCCGGGGGC GGAGTGTGCT CACGGCTCCT GCTGCCACCA GTGTAAGCTG 
TTGGCTCCTG GGACCCTGTG CCGCGAGCAG GCCAGGCAGT GTGACCTCCC GGAGTTCTGT 
ACGGGCAAGT CTCCCCACTG CCCTACCAAC TTCTACCAGA TGGATGGTAC CCCCTGTGAG 
GGCGGCCAGG CCTACTGCTA CAACGGCATG TGCCTCACCT ACCAGGAGCA GTGCCAGCAG 
CTGTGGGGAC CCGGAGCCCG ACCTGCCCCT GACCTCTGCT TCGAGAAGGT GAATGTGGCA 
GGAGACACCT TTGGAAACTG TGGAAAGGAC ATGAATGGTG AACACAGGAA GTGCAACATG 
AGAGATGCGA AGTGTGGGAA GATCCAGTGT CAGAGCTCTG AGGCCCGGCC CCTGGAGTCC 
AACGCGGTGC CCATTGACAC CACTATCATC ATGAATGGGA GGCAGATCCA GTGCCGGGGC 
ACCCACGTCT ACCGAGGTCC TGAGGAGGAG GGTGACATGC TGGACCCAGG GCTGGTGATG 
ACTGGAACCA AGTGTGGCTA CAACCATATT TGCTTTGAGG GGCAGTGCAG GAACACCTCC 
TTCTTTGAAA CTGAAGGCTG TGGGAAGAAG TGCAATGGCC ATGGGGTCTG TAACAACAAC 
CAGAACTGCC ACTGCCTGCC GGGCTGGGCC CCGCCCTTCT GCAACACACC GGGCCACGGG 
GGCAGTATCG ACAGTGGGCC TATGCCCCCT GAGAGTGTGG GTCCTGTGGT AGCTGGAGTG 
TTGGTGGCCA TCTTGGTGCT GGCGGTCCTC ATGCTGATGT ACTACTGCTG CAGACAGAAC 
AACAAACTAG GCCAACTCAA GCCCTCAGCT CTCCCTTCCA AGCTGAGGCA ACAGTTCAGT 
TGTCCCTTCA GGGTTTCTCA GAACAGCGGG ACTGGTCATG CCAACCCAAC TTTCAAGCTG 
CAGACGCCCC AGGGCAAGCG AAAGGTGATC AACACTCCGG AAATCCTGCG GAAGCCCTCC 
CAGCCTCCTC CCCGGCCCCC TCCAGATTAT CTGCGTGGTG GGTCCCCACC TGCACCACTG 
CCAGCTCACC TGAGCAGGGC TGCTAGGAAC TCCCCAGGGC CCGGGTCTCA AATAGAGAGG 
ACGGAGTCGT CCAGGAGGCC TCCTCCAAGC CGGCCAATTC CCCCCGCACC AAATTGCATC 
GTTTCCCAGG ACTTCTCCAG GCCTCGGCCG CCCCAGAAGG CACTCCCGGC AAACCCAGTG 
CCAGGCCGCA GGAGCCTCCC CAGGCCAGGA GGTGCATCCC CACTGCGGCC CCCTGGTGCT 
GGCCCTCAGC AGTCCCGGCC TCTGGCAGCA CTTGCCCCAA AGTTTCCAGA ATACAGATCA 
CAGAGGGCTG GAGGGATGAT TAGCTCGAAA ATCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ADAM19 ( XM_017010009.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016865498.1 Homo sapiens ADAM metallopeptidase domain 19 (ADAM19), transcript variant X2, mRNA.

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CloneID	OHu62150
Clone ID Related Accession (Same CDS sequence)	XM_011534682.2 , XM_017010009.1
Accession Version	XM_017010009.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1956bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	disintegrin and metalloproteinase domain-containing protein 19 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000005.10) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTGTGAAG TTTCAGAGAA TCCATATTCT ACCCTCTGGT CCTTTCTCAG TTGGAGGCGC 
AAGCTGCTTG CCCAGAAGTA CCATGACAAC GCCCAATTAA TCACGGGCAT GTCCTTCCAC 
GGCACCACCA TCGGCCTGGC CCCCCTCATG GCCATGTGCT CTGTGTACCA GTCTGGAGGA 
GTCAACATGG ACCACTCCGA GAATGCCATT GGCGTGGCTG CCACCATGGC CCACGAGATG 
GGCCACAACT TTGGCATGAC CCATGATTCT GCAGATTGCT GCTCGGCCAG TGCGGCTGAT 
GGTGGGTGCA TCATGGCAGC TGCCACTGGG CACCCCTTTC CCAAAGTGTT CAATGGATGC 
AACAGGAGGG AGCTGGACAG GTATCTGCAG TCAGGTGGTG GAATGTGTCT CTCCAACATG 
CCAGACACCA GGATGTTGTA TGGAGGCCGG AGGTGTGGGA ACGGGTATCT GGAAGATGGG 
GAAGAGTGTG ACTGTGGAGA AGAAGAGGAA TGTAACAACC CCTGCTGCAA TGCCTCTAAT 
TGTACCCTGA GGCCGGGGGC GGAGTGTGCT CACGGCTCCT GCTGCCACCA GTGTAAGCTG 
TTGGCTCCTG GGACCCTGTG CCGCGAGCAG GCCAGGCAGT GTGACCTCCC GGAGTTCTGT 
ACGGGCAAGT CTCCCCACTG CCCTACCAAC TTCTACCAGA TGGATGGTAC CCCCTGTGAG 
GGCGGCCAGG CCTACTGCTA CAACGGCATG TGCCTCACCT ACCAGGAGCA GTGCCAGCAG 
CTGTGGGGAC CCGGAGCCCG ACCTGCCCCT GACCTCTGCT TCGAGAAGGT GAATGTGGCA 
GGAGACACCT TTGGAAACTG TGGAAAGGAC ATGAATGGTG AACACAGGAA GTGCAACATG 
AGAGATGCGA AGTGTGGGAA GATCCAGTGT CAGAGCTCTG AGGCCCGGCC CCTGGAGTCC 
AACGCGGTGC CCATTGACAC CACTATCATC ATGAATGGGA GGCAGATCCA GTGCCGGGGC 
ACCCACGTCT ACCGAGGTCC TGAGGAGGAG GGTGACATGC TGGACCCAGG GCTGGTGATG 
ACTGGAACCA AGTGTGGCTA CAACCATATT TGCTTTGAGG GGCAGTGCAG GAACACCTCC 
TTCTTTGAAA CTGAAGGCTG TGGGAAGAAG TGCAATGGCC ATGGGGTCTG TAACAACAAC 
CAGAACTGCC ACTGCCTGCC GGGCTGGGCC CCGCCCTTCT GCAACACACC GGGCCACGGG 
GGCAGTATCG ACAGTGGGCC TATGCCCCCT GAGAGTGTGG GTCCTGTGGT AGCTGGAGTG 
TTGGTGGCCA TCTTGGTGCT GGCGGTCCTC ATGCTGATGT ACTACTGCTG CAGACAGAAC 
AACAAACTAG GCCAACTCAA GCCCTCAGCT CTCCCTTCCA AGCTGAGGCA ACAGTTCAGT 
TGTCCCTTCA GGGTTTCTCA GAACAGCGGG ACTGGTCATG CCAACCCAAC TTTCAAGCTG 
CAGACGCCCC AGGGCAAGCG AAAGGTGATC AACACTCCGG AAATCCTGCG GAAGCCCTCC 
CAGCCTCCTC CCCGGCCCCC TCCAGATTAT CTGCGTGGTG GGTCCCCACC TGCACCACTG 
CCAGCTCACC TGAGCAGGGC TGCTAGGAAC TCCCCAGGGC CCGGGTCTCA AATAGAGAGG 
ACGGAGTCGT CCAGGAGGCC TCCTCCAAGC CGGCCAATTC CCCCCGCACC AAATTGCATC 
GTTTCCCAGG ACTTCTCCAG GCCTCGGCCG CCCCAGAAGG CACTCCCGGC AAACCCAGTG 
CCAGGCCGCA GGAGCCTCCC CAGGCCAGGA GGTGCATCCC CACTGCGGCC CCCTGGTGCT 
GGCCCTCAGC AGTCCCGGCC TCTGGCAGCA CTTGCCCCAA AGTTTCCAGA ATACAGATCA 
CAGAGGGCTG GAGGGATGAT TAGCTCGAAA ATCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016865498.1
CDS	146..2101
Translation	MCEVSENPYSTLWSFLSWRRKLLAQKYHDNAQLITGMSFHGTTIGLAPLMAMCSVYQSGGVNMDHSENAIGVAATMAHEMGHNFGMTHDSADCCSASAADGGCIMAAATGHPFPKVFNGCNRRELDRYLQSGGGMCLSNMPDTRMLYGGRRCGNGYLEDGEECDCGEEEECNNPCCNASNCTLRPGAECAHGSCCHQCKLLAPGTLCREQARQCDLPEFCTGKSPHCPTNFYQMDGTPCEGGQAYCYNGMCLTYQEQCQQLWGPGARPAPDLCFEKVNVAGDTFGNCGKDMNGEHRKCNMRDAKCGKIQCQSSEARPLESNAVPIDTTIIMNGRQIQCRGTHVYRGPEEEGDMLDPGLVMTGTKCGYNHICFEGQCRNTSFFETEGCGKKCNGHGVCNNNQNCHCLPGWAPPFCNTPGHGGSIDSGPMPPESVGPVVAGVLVAILVLAVLMLMYYCCRQNNKLGQLKPSALPSKLRQQFSCPFRVSQNSGTGHANPTFKLQTPQGKRKVINTPEILRKPSQPPPRPPPDYLRGGSPPAPLPAHLSRAARNSPGPGSQIERTESSRRPPPSRPIPPAPNCIVSQDFSRPRPPQKALPANPVPGRRSLPRPGGASPLRPPGAGPQQSRPLAALAPKFPEYRSQRAGGMISSKI

Target ORF information:

RefSeq Version	XM_017010009.1
Organism	Homo sapiens(human)
Definition	Homo sapiens ADAM metallopeptidase domain 19 (ADAM19), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017010009.1

ORF Insert Sequence:

ATGTGTGAAG TTTCAGAGAA TCCATATTCT ACCCTCTGGT CCTTTCTCAG TTGGAGGCGC 
AAGCTGCTTG CCCAGAAGTA CCATGACAAC GCCCAATTAA TCACGGGCAT GTCCTTCCAC 
GGCACCACCA TCGGCCTGGC CCCCCTCATG GCCATGTGCT CTGTGTACCA GTCTGGAGGA 
GTCAACATGG ACCACTCCGA GAATGCCATT GGCGTGGCTG CCACCATGGC CCACGAGATG 
GGCCACAACT TTGGCATGAC CCATGATTCT GCAGATTGCT GCTCGGCCAG TGCGGCTGAT 
GGTGGGTGCA TCATGGCAGC TGCCACTGGG CACCCCTTTC CCAAAGTGTT CAATGGATGC 
AACAGGAGGG AGCTGGACAG GTATCTGCAG TCAGGTGGTG GAATGTGTCT CTCCAACATG 
CCAGACACCA GGATGTTGTA TGGAGGCCGG AGGTGTGGGA ACGGGTATCT GGAAGATGGG 
GAAGAGTGTG ACTGTGGAGA AGAAGAGGAA TGTAACAACC CCTGCTGCAA TGCCTCTAAT 
TGTACCCTGA GGCCGGGGGC GGAGTGTGCT CACGGCTCCT GCTGCCACCA GTGTAAGCTG 
TTGGCTCCTG GGACCCTGTG CCGCGAGCAG GCCAGGCAGT GTGACCTCCC GGAGTTCTGT 
ACGGGCAAGT CTCCCCACTG CCCTACCAAC TTCTACCAGA TGGATGGTAC CCCCTGTGAG 
GGCGGCCAGG CCTACTGCTA CAACGGCATG TGCCTCACCT ACCAGGAGCA GTGCCAGCAG 
CTGTGGGGAC CCGGAGCCCG ACCTGCCCCT GACCTCTGCT TCGAGAAGGT GAATGTGGCA 
GGAGACACCT TTGGAAACTG TGGAAAGGAC ATGAATGGTG AACACAGGAA GTGCAACATG 
AGAGATGCGA AGTGTGGGAA GATCCAGTGT CAGAGCTCTG AGGCCCGGCC CCTGGAGTCC 
AACGCGGTGC CCATTGACAC CACTATCATC ATGAATGGGA GGCAGATCCA GTGCCGGGGC 
ACCCACGTCT ACCGAGGTCC TGAGGAGGAG GGTGACATGC TGGACCCAGG GCTGGTGATG 
ACTGGAACCA AGTGTGGCTA CAACCATATT TGCTTTGAGG GGCAGTGCAG GAACACCTCC 
TTCTTTGAAA CTGAAGGCTG TGGGAAGAAG TGCAATGGCC ATGGGGTCTG TAACAACAAC 
CAGAACTGCC ACTGCCTGCC GGGCTGGGCC CCGCCCTTCT GCAACACACC GGGCCACGGG 
GGCAGTATCG ACAGTGGGCC TATGCCCCCT GAGAGTGTGG GTCCTGTGGT AGCTGGAGTG 
TTGGTGGCCA TCTTGGTGCT GGCGGTCCTC ATGCTGATGT ACTACTGCTG CAGACAGAAC 
AACAAACTAG GCCAACTCAA GCCCTCAGCT CTCCCTTCCA AGCTGAGGCA ACAGTTCAGT 
TGTCCCTTCA GGGTTTCTCA GAACAGCGGG ACTGGTCATG CCAACCCAAC TTTCAAGCTG 
CAGACGCCCC AGGGCAAGCG AAAGGTGATC AACACTCCGG AAATCCTGCG GAAGCCCTCC 
CAGCCTCCTC CCCGGCCCCC TCCAGATTAT CTGCGTGGTG GGTCCCCACC TGCACCACTG 
CCAGCTCACC TGAGCAGGGC TGCTAGGAAC TCCCCAGGGC CCGGGTCTCA AATAGAGAGG 
ACGGAGTCGT CCAGGAGGCC TCCTCCAAGC CGGCCAATTC CCCCCGCACC AAATTGCATC 
GTTTCCCAGG ACTTCTCCAG GCCTCGGCCG CCCCAGAAGG CACTCCCGGC AAACCCAGTG 
CCAGGCCGCA GGAGCCTCCC CAGGCCAGGA GGTGCATCCC CACTGCGGCC CCCTGGTGCT 
GGCCCTCAGC AGTCCCGGCC TCTGGCAGCA CTTGCCCCAA AGTTTCCAGA ATACAGATCA 
CAGAGGGCTG GAGGGATGAT TAGCTCGAAA ATCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ADAM19 ( NM_033274.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_150377.1 Homo sapiens ADAM metallopeptidase domain 19 (ADAM19), mRNA.

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CloneID	OHu00084
Clone ID Related Accession (Same CDS sequence)	NM_033274.5 , NM_033274.4
Accession Version	NM_033274.4	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2757bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-23
Organism	Homo sapiens(human)
Product	disintegrin and metalloproteinase domain-containing protein 19 preproprotein
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from HY088077.1, AK308182.1, AF311317.1, AC008676.6 and BC024214.2. This sequence is a reference standard in the RefSeqGene project. On May 10, 2013 this sequence version replaced NM_033274.3. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: Y13786.2, SRR1803613.164608.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCCAGGGG GCGCAGGCGC CGCCCGGCTC TGCTTGCTGG CGTTTGCCCT GCAGCCCCTC 
CGGCCGCGGG CGGCGCGGGA GCCTGGATGG ACAAGAGGAA GTGAGGAAGG CAGCCCCAAG 
CTGCAGCATG AACTTATCAT ACCTCAGTGG AAGACTTCAG AAAGCCCCGT GAGAGAAAAG 
CATCCACTCA AAGCTGAGCT CAGGGTAATG GCTGAGGGGC GAGAACTGAT CCTGGACCTG 
GAGAAGAATG AGCAACTTTT TGCTCCTTCC TACACAGAAA CCCATTATAC TTCAAGTGGT 
AACCCTCAAA CCACCACACG GAAATTGGAG GATCACTGCT TTTACCACGG CACGGTGAGG 
GAGACAGAAC TGTCCAGCGT CACGCTCAGC ACTTGCCGAG GAATTAGAGG ACTGATTACG 
GTGAGCAGCA ACCTCAGCTA CGTCATCGAG CCCCTCCCTG ACAGCAAGGG CCAACACCTT 
ATTTACAGAT CTGAACATCT CAAGCCGCCC CCGGGAAACT GTGGGTTCGA GCACTCCAAG 
CCCACCACCA GGGACTGGGC TCTTCAGTTT ACACAACAGA CCAAGAAGCG ACCTCGCAGG 
ATGAAAAGGG AAGATTTAAA CTCCATGAAG TATGTGGAGC TTTACCTCGT GGCTGATTAT 
TTAGAGTTTC AGAAGAATCG ACGAGACCAG GACGCCACCA AACACAAGCT CATAGAGATC 
GCCAACTATG TTGATAAGTT TTACCGATCC TTGAACATCC GGATTGCTCT CGTGGGCTTG 
GAAGTGTGGA CCCACGGGAA CATGTGTGAA GTTTCAGAGA ATCCATATTC TACCCTCTGG 
TCCTTTCTCA GTTGGAGGCG CAAGCTGCTT GCCCAGAAGT ACCATGACAA CGCCCAATTA 
ATCACGGGCA TGTCCTTCCA CGGCACCACC ATCGGCCTGG CCCCCCTCAT GGCCATGTGC 
TCTGTGTACC AGTCTGGAGG AGTCAACATG GACCACTCCG AGAATGCCAT TGGCGTGGCT 
GCCACCATGG CCCACGAGAT GGGCCACAAC TTTGGCATGA CCCATGATTC TGCAGATTGC 
TGCTCGGCCA GTGCGGCTGA TGGTGGGTGC ATCATGGCAG CTGCCACTGG GCACCCCTTT 
CCCAAAGTGT TCAATGGATG CAACAGGAGG GAGCTGGACA GGTATCTGCA GTCAGGTGGT 
GGAATGTGTC TCTCCAACAT GCCAGACACC AGGATGTTGT ATGGAGGCCG GAGGTGTGGG 
AACGGGTATC TGGAAGATGG GGAAGAGTGT GACTGTGGAG AAGAAGAGGA ATGTAACAAC 
CCCTGCTGCA ATGCCTCTAA TTGTACCCTG AGGCCGGGGG CGGAGTGTGC TCACGGCTCC 
TGCTGCCACC AGTGTAAGCT GTTGGCTCCT GGGACCCTGT GCCGCGAGCA GGCCAGGCAG 
TGTGACCTCC CGGAGTTCTG TACGGGCAAG TCTCCCCACT GCCCTACCAA CTTCTACCAG 
ATGGATGGTA CCCCCTGTGA GGGCGGCCAG GCCTACTGCT ACAACGGCAT GTGCCTCACC 
TACCAGGAGC AGTGCCAGCA GCTGTGGGGA CCCGGAGCCC GACCTGCCCC TGACCTCTGC 
TTCGAGAAGG TGAATGTGGC AGGAGACACC TTTGGAAACT GTGGAAAGGA CATGAATGGT 
GAACACAGGA AGTGCAACAT GAGAGATGCG AAGTGTGGGA AGATCCAGTG TCAGAGCTCT 
GAGGCCCGGC CCCTGGAGTC CAACGCGGTG CCCATTGACA CCACTATCAT CATGAATGGG 
AGGCAGATCC AGTGCCGGGG CACCCACGTC TACCGAGGTC CTGAGGAGGA GGGTGACATG 
CTGGACCCAG GGCTGGTGAT GACTGGAACC AAGTGTGGCT ACAACCATAT TTGCTTTGAG 
GGGCAGTGCA GGAACACCTC CTTCTTTGAA ACTGAAGGCT GTGGGAAGAA GTGCAATGGC 
CATGGGGTCT GTAACAACAA CCAGAACTGC CACTGCCTGC CGGGCTGGGC CCCGCCCTTC 
TGCAACACAC CGGGCCACGG GGGCAGTATC GACAGTGGGC CTATGCCCCC TGAGAGTGTG 
GGTCCTGTGG TAGCTGGAGT GTTGGTGGCC ATCTTGGTGC TGGCGGTCCT CATGCTGATG 
TACTACTGCT GCAGACAGAA CAACAAACTA GGCCAACTCA AGCCCTCAGC TCTCCCTTCC 
AAGCTGAGGC AACAGTTCAG TTGTCCCTTC AGGGTTTCTC AGAACAGCGG GACTGGTCAT 
GCCAACCCAA CTTTCAAGCT GCAGACGCCC CAGGGCAAGC GAAAGGTGAT CAACACTCCG 
GAAATCCTGC GGAAGCCCTC CCAGCCTCCT CCCCGGCCCC CTCCAGATTA TCTGCGTGGT 
GGGTCCCCAC CTGCACCACT GCCAGCTCAC CTGAGCAGGG CTGCTAGGAA CTCCCCAGGG 
CCCGGGTCTC AAATAGAGAG GACGGAGTCG TCCAGGAGGC CTCCTCCAAG CCGGCCAATT 
CCCCCCGCAC CAAATTGCAT CGTTTCCCAG GACTTCTCCA GGCCTCGGCC GCCCCAGAAG 
GCACTCCCGG CAAACCCAGT GCCAGGCCGC AGGAGCCTCC CCAGGCCAGG AGGTGCATCC 
CCACTGCGGC CCCCTGGTGC TGGCCCTCAG CAGTCCCGGC CTCTGGCAGC ACTTGCCCCA 
AAGTTTCCAG AATACAGATC ACAGAGGGCT GGAGGGATGA TTAGCTCGAA AATCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_150377.1
CDS	128..2884
Translation	MPGGAGAARLCLLAFALQPLRPRAAREPGWTRGSEEGSPKLQHELIIPQWKTSESPVREKHPLKAELRVMAEGRELILDLEKNEQLFAPSYTETHYTSSGNPQTTTRKLEDHCFYHGTVRETELSSVTLSTCRGIRGLITVSSNLSYVIEPLPDSKGQHLIYRSEHLKPPPGNCGFEHSKPTTRDWALQFTQQTKKRPRRMKREDLNSMKYVELYLVADYLEFQKNRRDQDATKHKLIEIANYVDKFYRSLNIRIALVGLEVWTHGNMCEVSENPYSTLWSFLSWRRKLLAQKYHDNAQLITGMSFHGTTIGLAPLMAMCSVYQSGGVNMDHSENAIGVAATMAHEMGHNFGMTHDSADCCSASAADGGCIMAAATGHPFPKVFNGCNRRELDRYLQSGGGMCLSNMPDTRMLYGGRRCGNGYLEDGEECDCGEEEECNNPCCNASNCTLRPGAECAHGSCCHQCKLLAPGTLCREQARQCDLPEFCTGKSPHCPTNFYQMDGTPCEGGQAYCYNGMCLTYQEQCQQLWGPGARPAPDLCFEKVNVAGDTFGNCGKDMNGEHRKCNMRDAKCGKIQCQSSEARPLESNAVPIDTTIIMNGRQIQCRGTHVYRGPEEEGDMLDPGLVMTGTKCGYNHICFEGQCRNTSFFETEGCGKKCNGHGVCNNNQNCHCLPGWAPPFCNTPGHGGSIDSGPMPPESVGPVVAGVLVAILVLAVLMLMYYCCRQNNKLGQLKPSALPSKLRQQFSCPFRVSQNSGTGHANPTFKLQTPQGKRKVINTPEILRKPSQPPPRPPPDYLRGGSPPAPLPAHLSRAARNSPGPGSQIERTESSRRPPPSRPIPPAPNCIVSQDFSRPRPPQKALPANPVPGRRSLPRPGGASPLRPPGAGPQQSRPLAALAPKFPEYRSQRAGGMISSKI

Target ORF information:

RefSeq Version	NM_033274.4
Organism	Homo sapiens(human)
Definition	Homo sapiens ADAM metallopeptidase domain 19 (ADAM19), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_033274.4

ORF Insert Sequence:

ATGCCAGGGG GCGCAGGCGC CGCCCGGCTC TGCTTGCTGG CGTTTGCCCT GCAGCCCCTC 
CGGCCGCGGG CGGCGCGGGA GCCTGGATGG ACAAGAGGAA GTGAGGAAGG CAGCCCCAAG 
CTGCAGCATG AACTTATCAT ACCTCAGTGG AAGACTTCAG AAAGCCCCGT GAGAGAAAAG 
CATCCACTCA AAGCTGAGCT CAGGGTAATG GCTGAGGGGC GAGAACTGAT CCTGGACCTG 
GAGAAGAATG AGCAACTTTT TGCTCCTTCC TACACAGAAA CCCATTATAC TTCAAGTGGT 
AACCCTCAAA CCACCACACG GAAATTGGAG GATCACTGCT TTTACCACGG CACGGTGAGG 
GAGACAGAAC TGTCCAGCGT CACGCTCAGC ACTTGCCGAG GAATTAGAGG ACTGATTACG 
GTGAGCAGCA ACCTCAGCTA CGTCATCGAG CCCCTCCCTG ACAGCAAGGG CCAACACCTT 
ATTTACAGAT CTGAACATCT CAAGCCGCCC CCGGGAAACT GTGGGTTCGA GCACTCCAAG 
CCCACCACCA GGGACTGGGC TCTTCAGTTT ACACAACAGA CCAAGAAGCG ACCTCGCAGG 
ATGAAAAGGG AAGATTTAAA CTCCATGAAG TATGTGGAGC TTTACCTCGT GGCTGATTAT 
TTAGAGTTTC AGAAGAATCG ACGAGACCAG GACGCCACCA AACACAAGCT CATAGAGATC 
GCCAACTATG TTGATAAGTT TTACCGATCC TTGAACATCC GGATTGCTCT CGTGGGCTTG 
GAAGTGTGGA CCCACGGGAA CATGTGTGAA GTTTCAGAGA ATCCATATTC TACCCTCTGG 
TCCTTTCTCA GTTGGAGGCG CAAGCTGCTT GCCCAGAAGT ACCATGACAA CGCCCAATTA 
ATCACGGGCA TGTCCTTCCA CGGCACCACC ATCGGCCTGG CCCCCCTCAT GGCCATGTGC 
TCTGTGTACC AGTCTGGAGG AGTCAACATG GACCACTCCG AGAATGCCAT TGGCGTGGCT 
GCCACCATGG CCCACGAGAT GGGCCACAAC TTTGGCATGA CCCATGATTC TGCAGATTGC 
TGCTCGGCCA GTGCGGCTGA TGGTGGGTGC ATCATGGCAG CTGCCACTGG GCACCCCTTT 
CCCAAAGTGT TCAATGGATG CAACAGGAGG GAGCTGGACA GGTATCTGCA GTCAGGTGGT 
GGAATGTGTC TCTCCAACAT GCCAGACACC AGGATGTTGT ATGGAGGCCG GAGGTGTGGG 
AACGGGTATC TGGAAGATGG GGAAGAGTGT GACTGTGGAG AAGAAGAGGA ATGTAACAAC 
CCCTGCTGCA ATGCCTCTAA TTGTACCCTG AGGCCGGGGG CGGAGTGTGC TCACGGCTCC 
TGCTGCCACC AGTGTAAGCT GTTGGCTCCT GGGACCCTGT GCCGCGAGCA GGCCAGGCAG 
TGTGACCTCC CGGAGTTCTG TACGGGCAAG TCTCCCCACT GCCCTACCAA CTTCTACCAG 
ATGGATGGTA CCCCCTGTGA GGGCGGCCAG GCCTACTGCT ACAACGGCAT GTGCCTCACC 
TACCAGGAGC AGTGCCAGCA GCTGTGGGGA CCCGGAGCCC GACCTGCCCC TGACCTCTGC 
TTCGAGAAGG TGAATGTGGC AGGAGACACC TTTGGAAACT GTGGAAAGGA CATGAATGGT 
GAACACAGGA AGTGCAACAT GAGAGATGCG AAGTGTGGGA AGATCCAGTG TCAGAGCTCT 
GAGGCCCGGC CCCTGGAGTC CAACGCGGTG CCCATTGACA CCACTATCAT CATGAATGGG 
AGGCAGATCC AGTGCCGGGG CACCCACGTC TACCGAGGTC CTGAGGAGGA GGGTGACATG 
CTGGACCCAG GGCTGGTGAT GACTGGAACC AAGTGTGGCT ACAACCATAT TTGCTTTGAG 
GGGCAGTGCA GGAACACCTC CTTCTTTGAA ACTGAAGGCT GTGGGAAGAA GTGCAATGGC 
CATGGGGTCT GTAACAACAA CCAGAACTGC CACTGCCTGC CGGGCTGGGC CCCGCCCTTC 
TGCAACACAC CGGGCCACGG GGGCAGTATC GACAGTGGGC CTATGCCCCC TGAGAGTGTG 
GGTCCTGTGG TAGCTGGAGT GTTGGTGGCC ATCTTGGTGC TGGCGGTCCT CATGCTGATG 
TACTACTGCT GCAGACAGAA CAACAAACTA GGCCAACTCA AGCCCTCAGC TCTCCCTTCC 
AAGCTGAGGC AACAGTTCAG TTGTCCCTTC AGGGTTTCTC AGAACAGCGG GACTGGTCAT 
GCCAACCCAA CTTTCAAGCT GCAGACGCCC CAGGGCAAGC GAAAGGTGAT CAACACTCCG 
GAAATCCTGC GGAAGCCCTC CCAGCCTCCT CCCCGGCCCC CTCCAGATTA TCTGCGTGGT 
GGGTCCCCAC CTGCACCACT GCCAGCTCAC CTGAGCAGGG CTGCTAGGAA CTCCCCAGGG 
CCCGGGTCTC AAATAGAGAG GACGGAGTCG TCCAGGAGGC CTCCTCCAAG CCGGCCAATT 
CCCCCCGCAC CAAATTGCAT CGTTTCCCAG GACTTCTCCA GGCCTCGGCC GCCCCAGAAG 
GCACTCCCGG CAAACCCAGT GCCAGGCCGC AGGAGCCTCC CCAGGCCAGG AGGTGCATCC 
CCACTGCGGC CCCCTGGTGC TGGCCCTCAG CAGTCCCGGC CTCTGGCAGC ACTTGCCCCA 
AAGTTTCCAG AATACAGATC ACAGAGGGCT GGAGGGATGA TTAGCTCGAA AATCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ADAM19 ( XM_005266003.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_005266060.1 Homo sapiens ADAM metallopeptidase domain 19 (ADAM19), transcript variant X1, mRNA.

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CloneID	OHu40078
Clone ID Related Accession (Same CDS sequence)	XM_005266003.2
Accession Version	XM_005266003.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2868bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-03-25
Organism	Homo sapiens(human)
Product	disintegrin and metalloproteinase domain-containing protein 19 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000005.10) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 12, 2015 this sequence version replaced XM_005266003.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Homo sapiens Annotation Release 109 Annotation Version :: 109 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCCAGGGG GCGCAGGCGC CGCCCGGCTC TGCTTGCTGG CGTTTGCCCT GCAGCCCCTC 
CGGCCGCGGG CGGCGCGGGA GCCTGGATGG ACAAGAGGAA GTGAGGAAGG CAGCCCCAAG 
CTGCAGCATG AACTTATCAT ACCTCAGTGG AAGACTTCAG AAAGCCCCGT GAGAGAAAAG 
CATCCACTCA AAGCTGAGCT CAGGGTAATG GCTGAGGGGC GAGAACTGAT CCTGGACCTG 
GAGAAGAATG AGCAACTTTT TGCTCCTTCC TACACAGAAA CCCATTATAC TTCAAGTGGT 
AACCCTCAAA CCACCACACG GAAATTGGAG GATCACTGCT TTTACCACGG CACGGTGAGG 
GAGACAGAAC TGTCCAGCGT CACGCTCAGC ACTTGCCGAG GAATTAGAGG ACTGATTACG 
GTGAGCAGCA ACCTCAGCTA CGTCATCGAG CCCCTCCCTG ACAGCAAGGG CCAACACCTT 
ATTTACAGAT CTGAACATCT CAAGCCGCCC CCGGGAAACT GTGGGTTCGA GCACTCCAAG 
CCCACCACCA GGGACTGGGC TCTTCAGTTT ACACAACAGA CCAAGAAGCG ACCTCGCAGG 
ATGAAAAGGG AAGATTTAAA CTCCATGAAG TATGTGGAGC TTTACCTCGT GGCTGATTAT 
TTAGAGTTTC AGAAGAATCG ACGAGACCAG GACGCCACCA AACACAAGCT CATAGAGATC 
GCCAACTATG TTGATAAGTT TTACCGATCC TTGAACATCC GGATTGCTCT CGTGGGCTTG 
GAAGTGTGGA CCCACGGGAA CATGTGTGAA GTTTCAGAGA ATCCATATTC TACCCTCTGG 
TCCTTTCTCA GTTGGAGGCG CAAGCTGCTT GCCCAGAAGT ACCATGACAA CGCCCAATTA 
ATCACGGGCA TGTCCTTCCA CGGCACCACC ATCGGCCTGG CCCCCCTCAT GGCCATGTGC 
TCTGTGTACC AGTCTGGAGG AGTCAACATG GACCACTCCG AGAATGCCAT TGGCGTGGCT 
GCCACCATGG CCCACGAGAT GGGCCACAAC TTTGGCATGA CCCATGATTC TGCAGATTGC 
TGCTCGGCCA GTGCGGCTGA TGGTGGGTGC ATCATGGCAG CTGCCACTGG GCACCCCTTT 
CCCAAAGTGT TCAATGGATG CAACAGGAGG GAGCTGGACA GGTATCTGCA GTCAGGTGGT 
GGAATGTGTC TCTCCAACAT GCCAGACACC AGGATGTTGT ATGGAGGCCG GAGGTGTGGG 
AACGGGTATC TGGAAGATGG GGAAGAGTGT GACTGTGGAG AAGAAGAGGA ATGTAACAAC 
CCCTGCTGCA ATGCCTCTAA TTGTACCCTG AGGCCGGGGG CGGAGTGTGC TCACGGCTCC 
TGCTGCCACC AGTGTAAGCT GTTGGCTCCT GGGACCCTGT GCCGCGAGCA GGCCAGGCAG 
TGTGACCTCC CGGAGTTCTG TACGGGCAAG TCTCCCCACT GCCCTACCAA CTTCTACCAG 
ATGGATGGTA CCCCCTGTGA GGGCGGCCAG GCCTACTGCT ACAACGGCAT GTGCCTCACC 
TACCAGGAGC AGTGCCAGCA GCTGTGGGGA CCCGGAGCCC GACCTGCCCC TGACCTCTGC 
TTCGAGAAGG TGAATGTGGC AGGAGACACC TTTGGAAACT GTGGAAAGGA CATGAATGGT 
GAACACAGGA AGTGCAACAT GAGAGATGCG AAGTGTGGGA AGATCCAGTG TCAGAGCTCT 
GAGGCCCGGC CCCTGGAGTC CAACGCGGTG CCCATTGACA CCACTATCAT CATGAATGGG 
AGGCAGATCC AGTGCCGGGG CACCCACGTC TACCGAGGTC CTGAGGAGGA GGGTGACATG 
CTGGACCCAG GGCTGGTGAT GACTGGAACC AAGTGTGGCT ACAACCATAT TTGCTTTGAG 
GGGCAGTGCA GGAACACCTC CTTCTTTGAA ACTGAAGGCT GTGGGAAGAA GTGCAATGGC 
CATGGGGTCT GTAACAACAA CCAGAACTGC CACTGCCTGC CGGGCTGGGC CCCGCCCTTC 
TGCAACACAC CGGGCCACGG GGGCAGTATC GACAGTGGGC CTATGCCCCC TGAGAGTGTG 
GGTCCTGTGG TAGCTGGAGT GTTGGTGGCC ATCTTGGTGC TGGCGGTCCT CATGCTGATG 
TACTACTGCT GCAGACAGAA CAACAAACTA GGCCAACTCA AGCCCTCAGC TCTCCCTTCC 
AAGCTGAGGC AACAGTTCAG TTGTCCCTTC AGGGTTTCTC AGAACAGCGG GACTGGTCAT 
GCCAACCCAA CTTTCAAGCT GCAGACGCCC CAGGGCAAGC GAAAGGTGAT CAACACTCCG 
GAAATCCTGC GGAAGCCCTC CCAGCCTCCT CCCCGGCCCC CTCCAGATTA TCTGCGTGGT 
GGGTCCCCAC CTGCACCACT GCCAGCTCAC CTGAGCAGGG CTGCTAGGAA CTCCCCAGGG 
CCCGGGTCTC AAATAGAGAG GACGGAGTCG TCCAGGAGGC CTCCTCCAAG CCGGCCAATT 
CCCCCCGCAC CAAATTGCAT CGTTTCCCAG GACTTCTCCA GGCCTCGGCC GCCCCAGAAG 
GCACTCCCGG CAAACCCAGT GCCAGGCCGC AGGAGCCTCC CCAGGCCAGG AGGTGCATCC 
CCACTGCGGC CCCCTGGTGC TGGCCCTCAG CAGTCCCGGC CTCTGGCAGC ACTTGCCCCA 
AAGGTGAGTC CACGGGAAGC CCTCAAGGTG AAAGCTGGTA CCAGAGGGCT CCAGGGGGGC 
AGGTGTAGAG TTGAGAAAAC AAAGCAATTC ATGCTTCTTG TGGTCTGGAC TGAACTTCCA 
GAACAAAAGC CAAGGGCAAA ACATTCATGT TTCTTGGTGC CCGCTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005266060.1
CDS	80..2947
Translation	MPGGAGAARLCLLAFALQPLRPRAAREPGWTRGSEEGSPKLQHELIIPQWKTSESPVREKHPLKAELRVMAEGRELILDLEKNEQLFAPSYTETHYTSSGNPQTTTRKLEDHCFYHGTVRETELSSVTLSTCRGIRGLITVSSNLSYVIEPLPDSKGQHLIYRSEHLKPPPGNCGFEHSKPTTRDWALQFTQQTKKRPRRMKREDLNSMKYVELYLVADYLEFQKNRRDQDATKHKLIEIANYVDKFYRSLNIRIALVGLEVWTHGNMCEVSENPYSTLWSFLSWRRKLLAQKYHDNAQLITGMSFHGTTIGLAPLMAMCSVYQSGGVNMDHSENAIGVAATMAHEMGHNFGMTHDSADCCSASAADGGCIMAAATGHPFPKVFNGCNRRELDRYLQSGGGMCLSNMPDTRMLYGGRRCGNGYLEDGEECDCGEEEECNNPCCNASNCTLRPGAECAHGSCCHQCKLLAPGTLCREQARQCDLPEFCTGKSPHCPTNFYQMDGTPCEGGQAYCYNGMCLTYQEQCQQLWGPGARPAPDLCFEKVNVAGDTFGNCGKDMNGEHRKCNMRDAKCGKIQCQSSEARPLESNAVPIDTTIIMNGRQIQCRGTHVYRGPEEEGDMLDPGLVMTGTKCGYNHICFEGQCRNTSFFETEGCGKKCNGHGVCNNNQNCHCLPGWAPPFCNTPGHGGSIDSGPMPPESVGPVVAGVLVAILVLAVLMLMYYCCRQNNKLGQLKPSALPSKLRQQFSCPFRVSQNSGTGHANPTFKLQTPQGKRKVINTPEILRKPSQPPPRPPPDYLRGGSPPAPLPAHLSRAARNSPGPGSQIERTESSRRPPPSRPIPPAPNCIVSQDFSRPRPPQKALPANPVPGRRSLPRPGGASPLRPPGAGPQQSRPLAALAPKVSPREALKVKAGTRGLQGGRCRVEKTKQFMLLVVWTELPEQKPRAKHSCFLVPA

Target ORF information:

RefSeq Version	XM_005266003.2
Organism	Homo sapiens(human)
Definition	Homo sapiens ADAM metallopeptidase domain 19 (ADAM19), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005266003.2

ORF Insert Sequence:

ATGCCAGGGG GCGCAGGCGC CGCCCGGCTC TGCTTGCTGG CGTTTGCCCT GCAGCCCCTC 
CGGCCGCGGG CGGCGCGGGA GCCTGGATGG ACAAGAGGAA GTGAGGAAGG CAGCCCCAAG 
CTGCAGCATG AACTTATCAT ACCTCAGTGG AAGACTTCAG AAAGCCCCGT GAGAGAAAAG 
CATCCACTCA AAGCTGAGCT CAGGGTAATG GCTGAGGGGC GAGAACTGAT CCTGGACCTG 
GAGAAGAATG AGCAACTTTT TGCTCCTTCC TACACAGAAA CCCATTATAC TTCAAGTGGT 
AACCCTCAAA CCACCACACG GAAATTGGAG GATCACTGCT TTTACCACGG CACGGTGAGG 
GAGACAGAAC TGTCCAGCGT CACGCTCAGC ACTTGCCGAG GAATTAGAGG ACTGATTACG 
GTGAGCAGCA ACCTCAGCTA CGTCATCGAG CCCCTCCCTG ACAGCAAGGG CCAACACCTT 
ATTTACAGAT CTGAACATCT CAAGCCGCCC CCGGGAAACT GTGGGTTCGA GCACTCCAAG 
CCCACCACCA GGGACTGGGC TCTTCAGTTT ACACAACAGA CCAAGAAGCG ACCTCGCAGG 
ATGAAAAGGG AAGATTTAAA CTCCATGAAG TATGTGGAGC TTTACCTCGT GGCTGATTAT 
TTAGAGTTTC AGAAGAATCG ACGAGACCAG GACGCCACCA AACACAAGCT CATAGAGATC 
GCCAACTATG TTGATAAGTT TTACCGATCC TTGAACATCC GGATTGCTCT CGTGGGCTTG 
GAAGTGTGGA CCCACGGGAA CATGTGTGAA GTTTCAGAGA ATCCATATTC TACCCTCTGG 
TCCTTTCTCA GTTGGAGGCG CAAGCTGCTT GCCCAGAAGT ACCATGACAA CGCCCAATTA 
ATCACGGGCA TGTCCTTCCA CGGCACCACC ATCGGCCTGG CCCCCCTCAT GGCCATGTGC 
TCTGTGTACC AGTCTGGAGG AGTCAACATG GACCACTCCG AGAATGCCAT TGGCGTGGCT 
GCCACCATGG CCCACGAGAT GGGCCACAAC TTTGGCATGA CCCATGATTC TGCAGATTGC 
TGCTCGGCCA GTGCGGCTGA TGGTGGGTGC ATCATGGCAG CTGCCACTGG GCACCCCTTT 
CCCAAAGTGT TCAATGGATG CAACAGGAGG GAGCTGGACA GGTATCTGCA GTCAGGTGGT 
GGAATGTGTC TCTCCAACAT GCCAGACACC AGGATGTTGT ATGGAGGCCG GAGGTGTGGG 
AACGGGTATC TGGAAGATGG GGAAGAGTGT GACTGTGGAG AAGAAGAGGA ATGTAACAAC 
CCCTGCTGCA ATGCCTCTAA TTGTACCCTG AGGCCGGGGG CGGAGTGTGC TCACGGCTCC 
TGCTGCCACC AGTGTAAGCT GTTGGCTCCT GGGACCCTGT GCCGCGAGCA GGCCAGGCAG 
TGTGACCTCC CGGAGTTCTG TACGGGCAAG TCTCCCCACT GCCCTACCAA CTTCTACCAG 
ATGGATGGTA CCCCCTGTGA GGGCGGCCAG GCCTACTGCT ACAACGGCAT GTGCCTCACC 
TACCAGGAGC AGTGCCAGCA GCTGTGGGGA CCCGGAGCCC GACCTGCCCC TGACCTCTGC 
TTCGAGAAGG TGAATGTGGC AGGAGACACC TTTGGAAACT GTGGAAAGGA CATGAATGGT 
GAACACAGGA AGTGCAACAT GAGAGATGCG AAGTGTGGGA AGATCCAGTG TCAGAGCTCT 
GAGGCCCGGC CCCTGGAGTC CAACGCGGTG CCCATTGACA CCACTATCAT CATGAATGGG 
AGGCAGATCC AGTGCCGGGG CACCCACGTC TACCGAGGTC CTGAGGAGGA GGGTGACATG 
CTGGACCCAG GGCTGGTGAT GACTGGAACC AAGTGTGGCT ACAACCATAT TTGCTTTGAG 
GGGCAGTGCA GGAACACCTC CTTCTTTGAA ACTGAAGGCT GTGGGAAGAA GTGCAATGGC 
CATGGGGTCT GTAACAACAA CCAGAACTGC CACTGCCTGC CGGGCTGGGC CCCGCCCTTC 
TGCAACACAC CGGGCCACGG GGGCAGTATC GACAGTGGGC CTATGCCCCC TGAGAGTGTG 
GGTCCTGTGG TAGCTGGAGT GTTGGTGGCC ATCTTGGTGC TGGCGGTCCT CATGCTGATG 
TACTACTGCT GCAGACAGAA CAACAAACTA GGCCAACTCA AGCCCTCAGC TCTCCCTTCC 
AAGCTGAGGC AACAGTTCAG TTGTCCCTTC AGGGTTTCTC AGAACAGCGG GACTGGTCAT 
GCCAACCCAA CTTTCAAGCT GCAGACGCCC CAGGGCAAGC GAAAGGTGAT CAACACTCCG 
GAAATCCTGC GGAAGCCCTC CCAGCCTCCT CCCCGGCCCC CTCCAGATTA TCTGCGTGGT 
GGGTCCCCAC CTGCACCACT GCCAGCTCAC CTGAGCAGGG CTGCTAGGAA CTCCCCAGGG 
CCCGGGTCTC AAATAGAGAG GACGGAGTCG TCCAGGAGGC CTCCTCCAAG CCGGCCAATT 
CCCCCCGCAC CAAATTGCAT CGTTTCCCAG GACTTCTCCA GGCCTCGGCC GCCCCAGAAG 
GCACTCCCGG CAAACCCAGT GCCAGGCCGC AGGAGCCTCC CCAGGCCAGG AGGTGCATCC 
CCACTGCGGC CCCCTGGTGC TGGCCCTCAG CAGTCCCGGC CTCTGGCAGC ACTTGCCCCA 
AAGGTGAGTC CACGGGAAGC CCTCAAGGTG AAAGCTGGTA CCAGAGGGCT CCAGGGGGGC 
AGGTGTAGAG TTGAGAAAAC AAAGCAATTC ATGCTTCTTG TGGTCTGGAC TGAACTTCCA 
GAACAAAAGC CAAGGGCAAA ACATTCATGT TTCTTGGTGC CCGCTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Proteomic characterization of human multiple myeloma bone marrow extracellular matrix.
Leukemia31(11)2426-2434(2017 Nov)
Glavey SV,Naba A,Manier S,Clauser K,Tahri S,Park J,Reagan MR,Moschetta M,Mishima Y,Gambella M,Rocci A,Sacco A,O'Dwyer ME,Asara JM,Palumbo A,Roccaro AM,Hynes RO,Ghobrial IM

Genetic Variants in IL6R and ADAM19 are Associated with COPD Severity in a Mexican Mestizo Population.
COPD13(5)610-5(2016 Oct)
P?rez-Rubio G,Silva-Zolezzi I,Fern?ndez-L?pez JC,Camarena ?,Vel?zquez-Uncal M,Morales-Mandujano F,Hern?ndez-Zenteno Rde J,Flores-Trujillo F,S?nchez-Romero C,Vel?zquez-Montero A,Espinosa de Los Monteros C,Sansores RH,Ram?rez-Venegas A,Falf?n-Valencia R

Genetic and cellular studies highlight that A Disintegrin and Metalloproteinase 19 is a protective biomarker in human prostate cancer.
BMC cancer16151(2016 Feb)
Hoyne G,Rudnicka C,Sang QX,Roycik M,Howarth S,Leedman P,Schlaich M,Candy P,Matthews V

MiR-145 suppressed human retinoblastoma cell proliferation and invasion by targeting ADAM19.
International journal of clinical and experimental pathology8(11)14521-7(2015)
Sun Z,Zhang A,Jiang T,Du Z,Che C,Wang F

Extracellular signal-regulated kinase phosphorylates tumor necrosis factor alpha-converting enzyme at threonine 735: a potential role in regulated shedding.
Molecular biology of the cell13(6)2031-44(2002 Jun)
D?az-Rodr?guez E,Montero JC,Espar?s-Ogando A,Yuste L,Pandiella A

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ADAM19 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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