TRADD cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	TRADD
Entrez Gene ID	8717
Full Name	TNFRSF1A associated via death domain
Synonyms	Hs.89862
General protein information	Preferred Names TNFRSF1A associated via death domain Names tumor necrosis factor receptor type 1-associated DEATH domain protein TNFR1-associated death domain protein tumor necrosis factor receptor type 1 associated death domain protein tumor necrosis factor receptor-1-associated protein
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 16 Map Location: 16q22.1
Summary	The protein encoded by this gene is a death domain containing adaptor molecule that interacts with TNFRSF1A/TNFR1 and mediates programmed cell death signaling and NF-kappaB activation. This protein binds adaptor protein TRAF2, reduces the recruitment of inhibitor-of-apoptosis proteins (IAPs) by TRAF2, and thus suppresses TRAF2 mediated apoptosis. This protein can also interact with receptor TNFRSF6/FAS and adaptor protein FADD/MORT1, and is involved in the Fas-induced cell death pathway. [provided by RefSeq, Jul 2008].
Disorder MIM:	603500

mRNA and Protein(s)

mRNA	Protein	Name
XM_011523420.1	XP_011521722.1	tumor necrosis factor receptor type 1-associated DEATH domain protein isoform X1
NM_003789.3	NP_003780.1	tumor necrosis factor receptor type 1-associated DEATH domain protein
NM_001323552.1	NP_001310481.1	tumor necrosis factor receptor type 1-associated DEATH domain protein
XM_005256213.3	XP_005256270.1	tumor necrosis factor receptor type 1-associated DEATH domain protein isoform X2
NM_001323552.2	NP_001310481.1	tumor necrosis factor receptor type 1-associated DEATH domain protein
XM_017023815.1	XP_016879304.1	tumor necrosis factor receptor type 1-associated DEATH domain protein isoform X1
NM_003789.4	NP_003780.1	tumor necrosis factor receptor type 1-associated DEATH domain protein
XM_005256213.4	XP_005256270.1	tumor necrosis factor receptor type 1-associated DEATH domain protein isoform X2

Pathways from BioSystems

Homologies

	LOC698160	XP_002802576.1
Gallus gallus (chicken)	TRADD	XP_004944196.1
Homo sapiens (human)	TRADD	NP_003780.1
Pan troglodytes (chimpanzee)	TRADD	XP_511022.3
Mus musculus (house mouse)	Tradd	NP_001028333.1
Xenopus tropicalis (tropical clawed frog)	tradd	XP_004913591.1
Rattus norvegicus (Norway rat)	Tradd	NP_001093950.1
Canis lupus familiaris (dog)	TRADD	XP_853998.2
Bos taurus (cattle)	TRADD	NP_001039361.1
Danio rerio (zebrafish)	tradd	NP_571682.1

Gene Ontology
Bibliography

Related articles in PubMed

Identification of TRADD as a potential biomarker in human uterine leiomyoma through iTRAQ based proteomic profiling.
Liu Y, Lu D, Sheng J, Luo L, Zhang W
Molecular and cellular probes3615-20(2017 Dec)

Structure of the C-terminal domain of TRADD reveals a novel fold in the death domain superfamily.
Zhang N, Yuan W, Fan JS, Lin Z
Scientific reports7(1)7073(2017 Aug)

TRADD, TRAF2, RIP1 and TAK1 are required for TNF-?-induced pro-labour mediators in human primary myometrial cells.
Lim R, Barker G, Lappas M
American journal of reproductive immunology (New York, N.Y. : 1989)78(1)(2017 Jul)

Nuclear TRADD prevents DNA damage-mediated death by facilitating non-homologous end-joining repair.
Koo GB, Ji JH, Cho H, Morgan MJ, Kim YS
Scientific reports7(1)3332(2017 Jun)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

These data for the first time identifies miR-485-5p/TRADD axis in hydrogen sulfide protecting against TNF-alpha-induced neuronal cell apoptosis.
Title: Hydrogen sulfide protects against TNF-? induced neuronal cell apoptosis through miR-485-5p/TRADD signaling.

By reducing the levels of TRADD, wild type CFTR suppresses downstream proinflammatory NFkappaB signaling.
Title: CFTR Controls the Activity of NF-?B by Enhancing the Degradation of TRADD.

The release of extracellular vesicles was triggered by TNFA from BEAS-2b cells.TNFA-triggered extracellular vesicles contained TNFR1 and TRADD.
Title: TNF? triggers release of extracellular vesicles containing TNFR1 and TRADD, which can modulate TNF? responses of the parental cells.

MicroRNA-30c-2-3p negatively regulates NF-kappaB signaling and cell cycle progression through downregulation of TRADD and CCNE1 in breast cancer.
Title: MicroRNA-30c-2-3p negatively regulates NF-?B signaling and cell cycle progression through downregulation of TRADD and CCNE1 in breast cancer.

NPM-RAR binding to TRADD selectively inhibits caspase activation, while allowing activation of NFkappaB and JNK
Title: NPM-RAR binding to TRADD selectively inhibits caspase activation, while allowing activation of NF?B and JNK.

The following TRADD gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the TRADD cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu26945	NM_001323552.2 Latest version!	Homo sapiens TNFRSF1A associated via death domain (TRADD), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$99.50-$139.30 $199.00
OHu26945	NM_003789.4 Latest version!	Homo sapiens TNFRSF1A associated via death domain (TRADD), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$99.50-$139.30 $199.00
OHu26945	XM_011523420.1 Latest version!	Homo sapiens TNFRSF1A-associated via death domain (TRADD), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$99.50-$139.30 $199.00
OHu26945	XM_017023815.1 Latest version!	Homo sapiens TNFRSF1A associated via death domain (TRADD), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$99.50-$139.30 $199.00
OHu49561	XM_005256213.4 Latest version!	Homo sapiens TNFRSF1A associated via death domain (TRADD), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
View Old Accession Versions >>
OHu26945	NM_001323552.1	Homo sapiens TNFRSF1A associated via death domain (TRADD), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$99.50-$139.30 $199.00
OHu26945	NM_003789.3	Homo sapiens TNFRSF1A associated via death domain (TRADD), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$99.50-$139.30 $199.00
OHu49561	XM_005256213.3	Homo sapiens TNFRSF1A associated via death domain (TRADD), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
Hide Old Accession Versions >>

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***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

TRADD ( NM_003789.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_003780.1 Homo sapiens TNFRSF1A associated via death domain (TRADD), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu26945
Clone ID Related Accession (Same CDS sequence)	XM_011523420.1 , NM_003789.3 , NM_001323552.1 , NM_001323552.2 , XM_017023815.1 , NM_003789.4
Accession Version	NM_003789.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 939bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-01
Organism	Homo sapiens(human)
Product	tumor necrosis factor receptor type 1-associated DEATH domain protein
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA353575.1, BC004491.2 and CA426418.1. On Sep 28, 2006 this sequence version replaced NM_003789.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1163655.43590.1, SRR1163655.647799.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCAGCTG GGCAAAATGG GCACGAAGAG TGGGTGGGCA GCGCATACCT GTTTGTGGAG 
TCCTCGCTGG ACAAGGTGGT CCTGTCGGAT GCCTACGCGC ACCCCCAGCA GAAGGTGGCA 
GTGTACAGGG CTCTGCAGGC TGCCTTGGCA GAGAGCGGCG GGAGCCCGGA CGTGCTGCAG 
ATGCTGAAGA TCCACCGCAG CGACCCGCAG CTGATCGTGC AGCTGCGATT CTGCGGGCGG 
CAGCCCTGTG GCCGCTTCCT CCGCGCCTAC CGCGAGGGGG CGCTGCGCGC CGCGCTGCAG 
AGGAGCCTGG CGGCCGCGCT CGCCCAGCAC TCGGTGCCGC TGCAACTGGA GCTGCGCGCC 
GGCGCCGAGC GGCTGGACGC TTTGCTGGCG GACGAGGAGC GCTGTTTGAG TTGCATCCTA 
GCCCAGCAGC CCGACCGGCT CCGGGATGAA GAACTGGCTG AGCTGGAGGA TGCGCTGCGA 
AATCTGAAGT GCGGCTCGGG GGCCCGGGGT GGCGACGGGG AGGTCGCTTC GGCCCCCTTG 
CAGCCCCCGG TGCCCTCTCT GTCGGAGGTG AAGCCGCCGC CGCCGCCGCC ACCTGCCCAG 
ACTTTTCTGT TCCAGGGTCA GCCTGTAGTG AATCGGCCGC TGAGCCTGAA GGACCAACAG 
ACGTTCGCGC GCTCTGTGGG TCTCAAATGG CGCAAGGTGG GGCGCTCACT GCAGCGAGGC 
TGCCGGGCGC TGCGGGACCC GGCGCTGGAC TCGCTGGCCT ACGAGTACGA GCGCGAGGGA 
CTGTACGAGC AGGCCTTCCA GCTGCTGCGG CGCTTCGTGC AGGCCGAGGG CCGCCGCGCC 
ACGCTGCAGC GCCTGGTGGA GGCACTCGAG GAGAACGAGC TCACCAGCCT GGCAGAGGAC 
TTGCTGGGCC TGACCGATCC CAATGGCGGC CTGGCCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_003780.1
CDS	81..1019
Translation	MAAGQNGHEEWVGSAYLFVESSLDKVVLSDAYAHPQQKVAVYRALQAALAESGGSPDVLQMLKIHRSDPQLIVQLRFCGRQPCGRFLRAYREGALRAALQRSLAAALAQHSVPLQLELRAGAERLDALLADEERCLSCILAQQPDRLRDEELAELEDALRNLKCGSGARGGDGEVASAPLQPPVPSLSEVKPPPPPPPAQTFLFQGQPVVNRPLSLKDQQTFARSVGLKWRKVGRSLQRGCRALRDPALDSLAYEYEREGLYEQAFQLLRRFVQAEGRRATLQRLVEALEENELTSLAEDLLGLTDPNGGLA

Target ORF information:

RefSeq Version	NM_003789.3
Organism	Homo sapiens(human)
Definition	Homo sapiens TNFRSF1A associated via death domain (TRADD), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_003789.3

ORF Insert Sequence:

ATGGCAGCTG GGCAAAATGG GCACGAAGAG TGGGTGGGCA GCGCATACCT GTTTGTGGAG 
TCCTCGCTGG ACAAGGTGGT CCTGTCGGAT GCCTACGCGC ACCCCCAGCA GAAGGTGGCA 
GTGTACAGGG CTCTGCAGGC TGCCTTGGCA GAGAGCGGCG GGAGCCCGGA CGTGCTGCAG 
ATGCTGAAGA TCCACCGCAG CGACCCGCAG CTGATCGTGC AGCTGCGATT CTGCGGGCGG 
CAGCCCTGTG GCCGCTTCCT CCGCGCCTAC CGCGAGGGGG CGCTGCGCGC CGCGCTGCAG 
AGGAGCCTGG CGGCCGCGCT CGCCCAGCAC TCGGTGCCGC TGCAACTGGA GCTGCGCGCC 
GGCGCCGAGC GGCTGGACGC TTTGCTGGCG GACGAGGAGC GCTGTTTGAG TTGCATCCTA 
GCCCAGCAGC CCGACCGGCT CCGGGATGAA GAACTGGCTG AGCTGGAGGA TGCGCTGCGA 
AATCTGAAGT GCGGCTCGGG GGCCCGGGGT GGCGACGGGG AGGTCGCTTC GGCCCCCTTG 
CAGCCCCCGG TGCCCTCTCT GTCGGAGGTG AAGCCGCCGC CGCCGCCGCC ACCTGCCCAG 
ACTTTTCTGT TCCAGGGTCA GCCTGTAGTG AATCGGCCGC TGAGCCTGAA GGACCAACAG 
ACGTTCGCGC GCTCTGTGGG TCTCAAATGG CGCAAGGTGG GGCGCTCACT GCAGCGAGGC 
TGCCGGGCGC TGCGGGACCC GGCGCTGGAC TCGCTGGCCT ACGAGTACGA GCGCGAGGGA 
CTGTACGAGC AGGCCTTCCA GCTGCTGCGG CGCTTCGTGC AGGCCGAGGG CCGCCGCGCC 
ACGCTGCAGC GCCTGGTGGA GGCACTCGAG GAGAACGAGC TCACCAGCCT GGCAGAGGAC 
TTGCTGGGCC TGACCGATCC CAATGGCGGC CTGGCCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TRADD ( NM_001323552.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001310481.1 Homo sapiens TNFRSF1A associated via death domain (TRADD), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu26945
Clone ID Related Accession (Same CDS sequence)	XM_011523420.1 , NM_003789.3 , NM_001323552.1 , NM_001323552.2 , XM_017023815.1 , NM_003789.4
Accession Version	NM_001323552.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 939bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-24
Organism	Homo sapiens(human)
Product	tumor necrosis factor receptor type 1-associated DEATH domain protein
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA353575.1, AC074143.5, BT006934.1 and CA426418.1. On Apr 22, 2016 this sequence version replaced XM_011523420.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: ERR279839.1380.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1968540, SAMEA1968968 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCAGCTG GGCAAAATGG GCACGAAGAG TGGGTGGGCA GCGCATACCT GTTTGTGGAG 
TCCTCGCTGG ACAAGGTGGT CCTGTCGGAT GCCTACGCGC ACCCCCAGCA GAAGGTGGCA 
GTGTACAGGG CTCTGCAGGC TGCCTTGGCA GAGAGCGGCG GGAGCCCGGA CGTGCTGCAG 
ATGCTGAAGA TCCACCGCAG CGACCCGCAG CTGATCGTGC AGCTGCGATT CTGCGGGCGG 
CAGCCCTGTG GCCGCTTCCT CCGCGCCTAC CGCGAGGGGG CGCTGCGCGC CGCGCTGCAG 
AGGAGCCTGG CGGCCGCGCT CGCCCAGCAC TCGGTGCCGC TGCAACTGGA GCTGCGCGCC 
GGCGCCGAGC GGCTGGACGC TTTGCTGGCG GACGAGGAGC GCTGTTTGAG TTGCATCCTA 
GCCCAGCAGC CCGACCGGCT CCGGGATGAA GAACTGGCTG AGCTGGAGGA TGCGCTGCGA 
AATCTGAAGT GCGGCTCGGG GGCCCGGGGT GGCGACGGGG AGGTCGCTTC GGCCCCCTTG 
CAGCCCCCGG TGCCCTCTCT GTCGGAGGTG AAGCCGCCGC CGCCGCCGCC ACCTGCCCAG 
ACTTTTCTGT TCCAGGGTCA GCCTGTAGTG AATCGGCCGC TGAGCCTGAA GGACCAACAG 
ACGTTCGCGC GCTCTGTGGG TCTCAAATGG CGCAAGGTGG GGCGCTCACT GCAGCGAGGC 
TGCCGGGCGC TGCGGGACCC GGCGCTGGAC TCGCTGGCCT ACGAGTACGA GCGCGAGGGA 
CTGTACGAGC AGGCCTTCCA GCTGCTGCGG CGCTTCGTGC AGGCCGAGGG CCGCCGCGCC 
ACGCTGCAGC GCCTGGTGGA GGCACTCGAG GAGAACGAGC TCACCAGCCT GGCAGAGGAC 
TTGCTGGGCC TGACCGATCC CAATGGCGGC CTGGCCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001310481.1
CDS	94..1032
Translation	MAAGQNGHEEWVGSAYLFVESSLDKVVLSDAYAHPQQKVAVYRALQAALAESGGSPDVLQMLKIHRSDPQLIVQLRFCGRQPCGRFLRAYREGALRAALQRSLAAALAQHSVPLQLELRAGAERLDALLADEERCLSCILAQQPDRLRDEELAELEDALRNLKCGSGARGGDGEVASAPLQPPVPSLSEVKPPPPPPPAQTFLFQGQPVVNRPLSLKDQQTFARSVGLKWRKVGRSLQRGCRALRDPALDSLAYEYEREGLYEQAFQLLRRFVQAEGRRATLQRLVEALEENELTSLAEDLLGLTDPNGGLA

Target ORF information:

RefSeq Version	NM_001323552.1
Organism	Homo sapiens(human)
Definition	Homo sapiens TNFRSF1A associated via death domain (TRADD), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001323552.1

ORF Insert Sequence:

ATGGCAGCTG GGCAAAATGG GCACGAAGAG TGGGTGGGCA GCGCATACCT GTTTGTGGAG 
TCCTCGCTGG ACAAGGTGGT CCTGTCGGAT GCCTACGCGC ACCCCCAGCA GAAGGTGGCA 
GTGTACAGGG CTCTGCAGGC TGCCTTGGCA GAGAGCGGCG GGAGCCCGGA CGTGCTGCAG 
ATGCTGAAGA TCCACCGCAG CGACCCGCAG CTGATCGTGC AGCTGCGATT CTGCGGGCGG 
CAGCCCTGTG GCCGCTTCCT CCGCGCCTAC CGCGAGGGGG CGCTGCGCGC CGCGCTGCAG 
AGGAGCCTGG CGGCCGCGCT CGCCCAGCAC TCGGTGCCGC TGCAACTGGA GCTGCGCGCC 
GGCGCCGAGC GGCTGGACGC TTTGCTGGCG GACGAGGAGC GCTGTTTGAG TTGCATCCTA 
GCCCAGCAGC CCGACCGGCT CCGGGATGAA GAACTGGCTG AGCTGGAGGA TGCGCTGCGA 
AATCTGAAGT GCGGCTCGGG GGCCCGGGGT GGCGACGGGG AGGTCGCTTC GGCCCCCTTG 
CAGCCCCCGG TGCCCTCTCT GTCGGAGGTG AAGCCGCCGC CGCCGCCGCC ACCTGCCCAG 
ACTTTTCTGT TCCAGGGTCA GCCTGTAGTG AATCGGCCGC TGAGCCTGAA GGACCAACAG 
ACGTTCGCGC GCTCTGTGGG TCTCAAATGG CGCAAGGTGG GGCGCTCACT GCAGCGAGGC 
TGCCGGGCGC TGCGGGACCC GGCGCTGGAC TCGCTGGCCT ACGAGTACGA GCGCGAGGGA 
CTGTACGAGC AGGCCTTCCA GCTGCTGCGG CGCTTCGTGC AGGCCGAGGG CCGCCGCGCC 
ACGCTGCAGC GCCTGGTGGA GGCACTCGAG GAGAACGAGC TCACCAGCCT GGCAGAGGAC 
TTGCTGGGCC TGACCGATCC CAATGGCGGC CTGGCCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TRADD ( NM_001323552.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001310481.1 Homo sapiens TNFRSF1A associated via death domain (TRADD), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu26945
Clone ID Related Accession (Same CDS sequence)	XM_011523420.1 , NM_003789.3 , NM_001323552.1 , NM_001323552.2 , XM_017023815.1 , NM_003789.4
Accession Version	NM_001323552.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 939bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-27
Organism	Homo sapiens(human)
Product	tumor necrosis factor receptor type 1-associated DEATH domain protein
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA353575.1, AC074143.5, BT006934.1 and CA426418.1. On May 31, 2019 this sequence version replaced NM_001323552.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: ERR279839.1380.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1968540, SAMEA1968968 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCAGCTG GGCAAAATGG GCACGAAGAG TGGGTGGGCA GCGCATACCT GTTTGTGGAG 
TCCTCGCTGG ACAAGGTGGT CCTGTCGGAT GCCTACGCGC ACCCCCAGCA GAAGGTGGCA 
GTGTACAGGG CTCTGCAGGC TGCCTTGGCA GAGAGCGGCG GGAGCCCGGA CGTGCTGCAG 
ATGCTGAAGA TCCACCGCAG CGACCCGCAG CTGATCGTGC AGCTGCGATT CTGCGGGCGG 
CAGCCCTGTG GCCGCTTCCT CCGCGCCTAC CGCGAGGGGG CGCTGCGCGC CGCGCTGCAG 
AGGAGCCTGG CGGCCGCGCT CGCCCAGCAC TCGGTGCCGC TGCAACTGGA GCTGCGCGCC 
GGCGCCGAGC GGCTGGACGC TTTGCTGGCG GACGAGGAGC GCTGTTTGAG TTGCATCCTA 
GCCCAGCAGC CCGACCGGCT CCGGGATGAA GAACTGGCTG AGCTGGAGGA TGCGCTGCGA 
AATCTGAAGT GCGGCTCGGG GGCCCGGGGT GGCGACGGGG AGGTCGCTTC GGCCCCCTTG 
CAGCCCCCGG TGCCCTCTCT GTCGGAGGTG AAGCCGCCGC CGCCGCCGCC ACCTGCCCAG 
ACTTTTCTGT TCCAGGGTCA GCCTGTAGTG AATCGGCCGC TGAGCCTGAA GGACCAACAG 
ACGTTCGCGC GCTCTGTGGG TCTCAAATGG CGCAAGGTGG GGCGCTCACT GCAGCGAGGC 
TGCCGGGCGC TGCGGGACCC GGCGCTGGAC TCGCTGGCCT ACGAGTACGA GCGCGAGGGA 
CTGTACGAGC AGGCCTTCCA GCTGCTGCGG CGCTTCGTGC AGGCCGAGGG CCGCCGCGCC 
ACGCTGCAGC GCCTGGTGGA GGCACTCGAG GAGAACGAGC TCACCAGCCT GGCAGAGGAC 
TTGCTGGGCC TGACCGATCC CAATGGCGGC CTGGCCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001310481.1
CDS	94..1032
Translation	MAAGQNGHEEWVGSAYLFVESSLDKVVLSDAYAHPQQKVAVYRALQAALAESGGSPDVLQMLKIHRSDPQLIVQLRFCGRQPCGRFLRAYREGALRAALQRSLAAALAQHSVPLQLELRAGAERLDALLADEERCLSCILAQQPDRLRDEELAELEDALRNLKCGSGARGGDGEVASAPLQPPVPSLSEVKPPPPPPPAQTFLFQGQPVVNRPLSLKDQQTFARSVGLKWRKVGRSLQRGCRALRDPALDSLAYEYEREGLYEQAFQLLRRFVQAEGRRATLQRLVEALEENELTSLAEDLLGLTDPNGGLA

Target ORF information:

RefSeq Version	NM_001323552.2
Organism	Homo sapiens(human)
Definition	Homo sapiens TNFRSF1A associated via death domain (TRADD), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001323552.2

ORF Insert Sequence:

ATGGCAGCTG GGCAAAATGG GCACGAAGAG TGGGTGGGCA GCGCATACCT GTTTGTGGAG 
TCCTCGCTGG ACAAGGTGGT CCTGTCGGAT GCCTACGCGC ACCCCCAGCA GAAGGTGGCA 
GTGTACAGGG CTCTGCAGGC TGCCTTGGCA GAGAGCGGCG GGAGCCCGGA CGTGCTGCAG 
ATGCTGAAGA TCCACCGCAG CGACCCGCAG CTGATCGTGC AGCTGCGATT CTGCGGGCGG 
CAGCCCTGTG GCCGCTTCCT CCGCGCCTAC CGCGAGGGGG CGCTGCGCGC CGCGCTGCAG 
AGGAGCCTGG CGGCCGCGCT CGCCCAGCAC TCGGTGCCGC TGCAACTGGA GCTGCGCGCC 
GGCGCCGAGC GGCTGGACGC TTTGCTGGCG GACGAGGAGC GCTGTTTGAG TTGCATCCTA 
GCCCAGCAGC CCGACCGGCT CCGGGATGAA GAACTGGCTG AGCTGGAGGA TGCGCTGCGA 
AATCTGAAGT GCGGCTCGGG GGCCCGGGGT GGCGACGGGG AGGTCGCTTC GGCCCCCTTG 
CAGCCCCCGG TGCCCTCTCT GTCGGAGGTG AAGCCGCCGC CGCCGCCGCC ACCTGCCCAG 
ACTTTTCTGT TCCAGGGTCA GCCTGTAGTG AATCGGCCGC TGAGCCTGAA GGACCAACAG 
ACGTTCGCGC GCTCTGTGGG TCTCAAATGG CGCAAGGTGG GGCGCTCACT GCAGCGAGGC 
TGCCGGGCGC TGCGGGACCC GGCGCTGGAC TCGCTGGCCT ACGAGTACGA GCGCGAGGGA 
CTGTACGAGC AGGCCTTCCA GCTGCTGCGG CGCTTCGTGC AGGCCGAGGG CCGCCGCGCC 
ACGCTGCAGC GCCTGGTGGA GGCACTCGAG GAGAACGAGC TCACCAGCCT GGCAGAGGAC 
TTGCTGGGCC TGACCGATCC CAATGGCGGC CTGGCCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TRADD ( NM_003789.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_003780.1 Homo sapiens TNFRSF1A associated via death domain (TRADD), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu26945
Clone ID Related Accession (Same CDS sequence)	XM_011523420.1 , NM_003789.3 , NM_001323552.1 , NM_001323552.2 , XM_017023815.1 , NM_003789.4
Accession Version	NM_003789.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 939bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-25
Organism	Homo sapiens(human)
Product	tumor necrosis factor receptor type 1-associated DEATH domain protein
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA353575.1, BC004491.2 and CA426418.1. On Nov 22, 2018 this sequence version replaced NM_003789.3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR3476690.500582.1, SRR1163657.329789.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000345057.9/ ENSP00000341268.4 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGCAGCTG GGCAAAATGG GCACGAAGAG TGGGTGGGCA GCGCATACCT GTTTGTGGAG 
TCCTCGCTGG ACAAGGTGGT CCTGTCGGAT GCCTACGCGC ACCCCCAGCA GAAGGTGGCA 
GTGTACAGGG CTCTGCAGGC TGCCTTGGCA GAGAGCGGCG GGAGCCCGGA CGTGCTGCAG 
ATGCTGAAGA TCCACCGCAG CGACCCGCAG CTGATCGTGC AGCTGCGATT CTGCGGGCGG 
CAGCCCTGTG GCCGCTTCCT CCGCGCCTAC CGCGAGGGGG CGCTGCGCGC CGCGCTGCAG 
AGGAGCCTGG CGGCCGCGCT CGCCCAGCAC TCGGTGCCGC TGCAACTGGA GCTGCGCGCC 
GGCGCCGAGC GGCTGGACGC TTTGCTGGCG GACGAGGAGC GCTGTTTGAG TTGCATCCTA 
GCCCAGCAGC CCGACCGGCT CCGGGATGAA GAACTGGCTG AGCTGGAGGA TGCGCTGCGA 
AATCTGAAGT GCGGCTCGGG GGCCCGGGGT GGCGACGGGG AGGTCGCTTC GGCCCCCTTG 
CAGCCCCCGG TGCCCTCTCT GTCGGAGGTG AAGCCGCCGC CGCCGCCGCC ACCTGCCCAG 
ACTTTTCTGT TCCAGGGTCA GCCTGTAGTG AATCGGCCGC TGAGCCTGAA GGACCAACAG 
ACGTTCGCGC GCTCTGTGGG TCTCAAATGG CGCAAGGTGG GGCGCTCACT GCAGCGAGGC 
TGCCGGGCGC TGCGGGACCC GGCGCTGGAC TCGCTGGCCT ACGAGTACGA GCGCGAGGGA 
CTGTACGAGC AGGCCTTCCA GCTGCTGCGG CGCTTCGTGC AGGCCGAGGG CCGCCGCGCC 
ACGCTGCAGC GCCTGGTGGA GGCACTCGAG GAGAACGAGC TCACCAGCCT GGCAGAGGAC 
TTGCTGGGCC TGACCGATCC CAATGGCGGC CTGGCCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_003780.1
CDS	81..1019
Translation	MAAGQNGHEEWVGSAYLFVESSLDKVVLSDAYAHPQQKVAVYRALQAALAESGGSPDVLQMLKIHRSDPQLIVQLRFCGRQPCGRFLRAYREGALRAALQRSLAAALAQHSVPLQLELRAGAERLDALLADEERCLSCILAQQPDRLRDEELAELEDALRNLKCGSGARGGDGEVASAPLQPPVPSLSEVKPPPPPPPAQTFLFQGQPVVNRPLSLKDQQTFARSVGLKWRKVGRSLQRGCRALRDPALDSLAYEYEREGLYEQAFQLLRRFVQAEGRRATLQRLVEALEENELTSLAEDLLGLTDPNGGLA

Target ORF information:

RefSeq Version	NM_003789.4
Organism	Homo sapiens(human)
Definition	Homo sapiens TNFRSF1A associated via death domain (TRADD), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_003789.4

ORF Insert Sequence:

ATGGCAGCTG GGCAAAATGG GCACGAAGAG TGGGTGGGCA GCGCATACCT GTTTGTGGAG 
TCCTCGCTGG ACAAGGTGGT CCTGTCGGAT GCCTACGCGC ACCCCCAGCA GAAGGTGGCA 
GTGTACAGGG CTCTGCAGGC TGCCTTGGCA GAGAGCGGCG GGAGCCCGGA CGTGCTGCAG 
ATGCTGAAGA TCCACCGCAG CGACCCGCAG CTGATCGTGC AGCTGCGATT CTGCGGGCGG 
CAGCCCTGTG GCCGCTTCCT CCGCGCCTAC CGCGAGGGGG CGCTGCGCGC CGCGCTGCAG 
AGGAGCCTGG CGGCCGCGCT CGCCCAGCAC TCGGTGCCGC TGCAACTGGA GCTGCGCGCC 
GGCGCCGAGC GGCTGGACGC TTTGCTGGCG GACGAGGAGC GCTGTTTGAG TTGCATCCTA 
GCCCAGCAGC CCGACCGGCT CCGGGATGAA GAACTGGCTG AGCTGGAGGA TGCGCTGCGA 
AATCTGAAGT GCGGCTCGGG GGCCCGGGGT GGCGACGGGG AGGTCGCTTC GGCCCCCTTG 
CAGCCCCCGG TGCCCTCTCT GTCGGAGGTG AAGCCGCCGC CGCCGCCGCC ACCTGCCCAG 
ACTTTTCTGT TCCAGGGTCA GCCTGTAGTG AATCGGCCGC TGAGCCTGAA GGACCAACAG 
ACGTTCGCGC GCTCTGTGGG TCTCAAATGG CGCAAGGTGG GGCGCTCACT GCAGCGAGGC 
TGCCGGGCGC TGCGGGACCC GGCGCTGGAC TCGCTGGCCT ACGAGTACGA GCGCGAGGGA 
CTGTACGAGC AGGCCTTCCA GCTGCTGCGG CGCTTCGTGC AGGCCGAGGG CCGCCGCGCC 
ACGCTGCAGC GCCTGGTGGA GGCACTCGAG GAGAACGAGC TCACCAGCCT GGCAGAGGAC 
TTGCTGGGCC TGACCGATCC CAATGGCGGC CTGGCCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TRADD ( XM_011523420.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_011521722.1 Homo sapiens TNFRSF1A-associated via death domain (TRADD), transcript variant X1, mRNA.

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CloneID	OHu26945
Clone ID Related Accession (Same CDS sequence)	XM_011523420.1 , NM_003789.3 , NM_001323552.1 , NM_001323552.2 , XM_017023815.1 , NM_003789.4
Accession Version	XM_011523420.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 939bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2015-03-11
Organism	Homo sapiens(Human)
Product	tumor necrosis factor receptor type 1-associated DEATH domain protein isoform X1
Comment

ATGGCAGCTG GGCAAAATGG GCACGAAGAG TGGGTGGGCA GCGCATACCT GTTTGTGGAG 
TCCTCGCTGG ACAAGGTGGT CCTGTCGGAT GCCTACGCGC ACCCCCAGCA GAAGGTGGCA 
GTGTACAGGG CTCTGCAGGC TGCCTTGGCA GAGAGCGGCG GGAGCCCGGA CGTGCTGCAG 
ATGCTGAAGA TCCACCGCAG CGACCCGCAG CTGATCGTGC AGCTGCGATT CTGCGGGCGG 
CAGCCCTGTG GCCGCTTCCT CCGCGCCTAC CGCGAGGGGG CGCTGCGCGC CGCGCTGCAG 
AGGAGCCTGG CGGCCGCGCT CGCCCAGCAC TCGGTGCCGC TGCAACTGGA GCTGCGCGCC 
GGCGCCGAGC GGCTGGACGC TTTGCTGGCG GACGAGGAGC GCTGTTTGAG TTGCATCCTA 
GCCCAGCAGC CCGACCGGCT CCGGGATGAA GAACTGGCTG AGCTGGAGGA TGCGCTGCGA 
AATCTGAAGT GCGGCTCGGG GGCCCGGGGT GGCGACGGGG AGGTCGCTTC GGCCCCCTTG 
CAGCCCCCGG TGCCCTCTCT GTCGGAGGTG AAGCCGCCGC CGCCGCCGCC ACCTGCCCAG 
ACTTTTCTGT TCCAGGGTCA GCCTGTAGTG AATCGGCCGC TGAGCCTGAA GGACCAACAG 
ACGTTCGCGC GCTCTGTGGG TCTCAAATGG CGCAAGGTGG GGCGCTCACT GCAGCGAGGC 
TGCCGGGCGC TGCGGGACCC GGCGCTGGAC TCGCTGGCCT ACGAGTACGA GCGCGAGGGA 
CTGTACGAGC AGGCCTTCCA GCTGCTGCGG CGCTTCGTGC AGGCCGAGGG CCGCCGCGCC 
ACGCTGCAGC GCCTGGTGGA GGCACTCGAG GAGAACGAGC TCACCAGCCT GGCAGAGGAC 
TTGCTGGGCC TGACCGATCC CAATGGCGGC CTGGCCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011521722.1
Translation	MAAGQNGHEEWVGSAYLFVESSLDKVVLSDAYAHPQQKVAVYRALQAALAESGGSPDVLQMLKIHRSDPQLIVQLRFCGRQPCGRFLRAYREGALRAALQRSLAAALAQHSVPLQLELRAGAERLDALLADEERCLSCILAQQPDRLRDEELAELEDALRNLKCGSGARGGDGEVASAPLQPPVPSLSEVKPPPPPPPAQTFLFQGQPVVNRPLSLKDQQTFARSVGLKWRKVGRSLQRGCRALRDPALDSLAYEYEREGLYEQAFQLLRRFVQAEGRRATLQRLVEALEENELTSLAEDLLGLTDPNGGLA

Target ORF information:

RefSeq Version	XM_011523420.1
Organism	Homo sapiens(Human)
Definition	Homo sapiens TNFRSF1A-associated via death domain (TRADD), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011523420.1

ORF Insert Sequence:

ATGGCAGCTG GGCAAAATGG GCACGAAGAG TGGGTGGGCA GCGCATACCT GTTTGTGGAG 
TCCTCGCTGG ACAAGGTGGT CCTGTCGGAT GCCTACGCGC ACCCCCAGCA GAAGGTGGCA 
GTGTACAGGG CTCTGCAGGC TGCCTTGGCA GAGAGCGGCG GGAGCCCGGA CGTGCTGCAG 
ATGCTGAAGA TCCACCGCAG CGACCCGCAG CTGATCGTGC AGCTGCGATT CTGCGGGCGG 
CAGCCCTGTG GCCGCTTCCT CCGCGCCTAC CGCGAGGGGG CGCTGCGCGC CGCGCTGCAG 
AGGAGCCTGG CGGCCGCGCT CGCCCAGCAC TCGGTGCCGC TGCAACTGGA GCTGCGCGCC 
GGCGCCGAGC GGCTGGACGC TTTGCTGGCG GACGAGGAGC GCTGTTTGAG TTGCATCCTA 
GCCCAGCAGC CCGACCGGCT CCGGGATGAA GAACTGGCTG AGCTGGAGGA TGCGCTGCGA 
AATCTGAAGT GCGGCTCGGG GGCCCGGGGT GGCGACGGGG AGGTCGCTTC GGCCCCCTTG 
CAGCCCCCGG TGCCCTCTCT GTCGGAGGTG AAGCCGCCGC CGCCGCCGCC ACCTGCCCAG 
ACTTTTCTGT TCCAGGGTCA GCCTGTAGTG AATCGGCCGC TGAGCCTGAA GGACCAACAG 
ACGTTCGCGC GCTCTGTGGG TCTCAAATGG CGCAAGGTGG GGCGCTCACT GCAGCGAGGC 
TGCCGGGCGC TGCGGGACCC GGCGCTGGAC TCGCTGGCCT ACGAGTACGA GCGCGAGGGA 
CTGTACGAGC AGGCCTTCCA GCTGCTGCGG CGCTTCGTGC AGGCCGAGGG CCGCCGCGCC 
ACGCTGCAGC GCCTGGTGGA GGCACTCGAG GAGAACGAGC TCACCAGCCT GGCAGAGGAC 
TTGCTGGGCC TGACCGATCC CAATGGCGGC CTGGCCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TRADD ( XM_017023815.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016879304.1 Homo sapiens TNFRSF1A associated via death domain (TRADD), transcript variant X1, mRNA.

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CloneID	OHu26945
Clone ID Related Accession (Same CDS sequence)	XM_011523420.1 , NM_003789.3 , NM_001323552.1 , NM_001323552.2 , XM_017023815.1 , NM_003789.4
Accession Version	XM_017023815.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 939bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	tumor necrosis factor receptor type 1-associated DEATH domain protein isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000016.10) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCAGCTG GGCAAAATGG GCACGAAGAG TGGGTGGGCA GCGCATACCT GTTTGTGGAG 
TCCTCGCTGG ACAAGGTGGT CCTGTCGGAT GCCTACGCGC ACCCCCAGCA GAAGGTGGCA 
GTGTACAGGG CTCTGCAGGC TGCCTTGGCA GAGAGCGGCG GGAGCCCGGA CGTGCTGCAG 
ATGCTGAAGA TCCACCGCAG CGACCCGCAG CTGATCGTGC AGCTGCGATT CTGCGGGCGG 
CAGCCCTGTG GCCGCTTCCT CCGCGCCTAC CGCGAGGGGG CGCTGCGCGC CGCGCTGCAG 
AGGAGCCTGG CGGCCGCGCT CGCCCAGCAC TCGGTGCCGC TGCAACTGGA GCTGCGCGCC 
GGCGCCGAGC GGCTGGACGC TTTGCTGGCG GACGAGGAGC GCTGTTTGAG TTGCATCCTA 
GCCCAGCAGC CCGACCGGCT CCGGGATGAA GAACTGGCTG AGCTGGAGGA TGCGCTGCGA 
AATCTGAAGT GCGGCTCGGG GGCCCGGGGT GGCGACGGGG AGGTCGCTTC GGCCCCCTTG 
CAGCCCCCGG TGCCCTCTCT GTCGGAGGTG AAGCCGCCGC CGCCGCCGCC ACCTGCCCAG 
ACTTTTCTGT TCCAGGGTCA GCCTGTAGTG AATCGGCCGC TGAGCCTGAA GGACCAACAG 
ACGTTCGCGC GCTCTGTGGG TCTCAAATGG CGCAAGGTGG GGCGCTCACT GCAGCGAGGC 
TGCCGGGCGC TGCGGGACCC GGCGCTGGAC TCGCTGGCCT ACGAGTACGA GCGCGAGGGA 
CTGTACGAGC AGGCCTTCCA GCTGCTGCGG CGCTTCGTGC AGGCCGAGGG CCGCCGCGCC 
ACGCTGCAGC GCCTGGTGGA GGCACTCGAG GAGAACGAGC TCACCAGCCT GGCAGAGGAC 
TTGCTGGGCC TGACCGATCC CAATGGCGGC CTGGCCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016879304.1
CDS	147..1085
Translation	MAAGQNGHEEWVGSAYLFVESSLDKVVLSDAYAHPQQKVAVYRALQAALAESGGSPDVLQMLKIHRSDPQLIVQLRFCGRQPCGRFLRAYREGALRAALQRSLAAALAQHSVPLQLELRAGAERLDALLADEERCLSCILAQQPDRLRDEELAELEDALRNLKCGSGARGGDGEVASAPLQPPVPSLSEVKPPPPPPPAQTFLFQGQPVVNRPLSLKDQQTFARSVGLKWRKVGRSLQRGCRALRDPALDSLAYEYEREGLYEQAFQLLRRFVQAEGRRATLQRLVEALEENELTSLAEDLLGLTDPNGGLA

Target ORF information:

RefSeq Version	XM_017023815.1
Organism	Homo sapiens(human)
Definition	Homo sapiens TNFRSF1A associated via death domain (TRADD), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017023815.1

ORF Insert Sequence:

ATGGCAGCTG GGCAAAATGG GCACGAAGAG TGGGTGGGCA GCGCATACCT GTTTGTGGAG 
TCCTCGCTGG ACAAGGTGGT CCTGTCGGAT GCCTACGCGC ACCCCCAGCA GAAGGTGGCA 
GTGTACAGGG CTCTGCAGGC TGCCTTGGCA GAGAGCGGCG GGAGCCCGGA CGTGCTGCAG 
ATGCTGAAGA TCCACCGCAG CGACCCGCAG CTGATCGTGC AGCTGCGATT CTGCGGGCGG 
CAGCCCTGTG GCCGCTTCCT CCGCGCCTAC CGCGAGGGGG CGCTGCGCGC CGCGCTGCAG 
AGGAGCCTGG CGGCCGCGCT CGCCCAGCAC TCGGTGCCGC TGCAACTGGA GCTGCGCGCC 
GGCGCCGAGC GGCTGGACGC TTTGCTGGCG GACGAGGAGC GCTGTTTGAG TTGCATCCTA 
GCCCAGCAGC CCGACCGGCT CCGGGATGAA GAACTGGCTG AGCTGGAGGA TGCGCTGCGA 
AATCTGAAGT GCGGCTCGGG GGCCCGGGGT GGCGACGGGG AGGTCGCTTC GGCCCCCTTG 
CAGCCCCCGG TGCCCTCTCT GTCGGAGGTG AAGCCGCCGC CGCCGCCGCC ACCTGCCCAG 
ACTTTTCTGT TCCAGGGTCA GCCTGTAGTG AATCGGCCGC TGAGCCTGAA GGACCAACAG 
ACGTTCGCGC GCTCTGTGGG TCTCAAATGG CGCAAGGTGG GGCGCTCACT GCAGCGAGGC 
TGCCGGGCGC TGCGGGACCC GGCGCTGGAC TCGCTGGCCT ACGAGTACGA GCGCGAGGGA 
CTGTACGAGC AGGCCTTCCA GCTGCTGCGG CGCTTCGTGC AGGCCGAGGG CCGCCGCGCC 
ACGCTGCAGC GCCTGGTGGA GGCACTCGAG GAGAACGAGC TCACCAGCCT GGCAGAGGAC 
TTGCTGGGCC TGACCGATCC CAATGGCGGC CTGGCCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TRADD ( XM_005256213.3 ) cDNA ORF clone, Homo sapiens(human) -> XP_005256270.1 Homo sapiens TNFRSF1A associated via death domain (TRADD), transcript variant X2, mRNA.

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CloneID	OHu49561
Clone ID Related Accession (Same CDS sequence)	XM_005256213.3 , XM_005256213.4
Accession Version	XM_005256213.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 759bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	tumor necrosis factor receptor type 1-associated DEATH domain protein isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000016.10) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_005256213.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCTGAAGA TCCACCGCAG CGACCCGCAG CTGATCGTGC AGCTGCGATT CTGCGGGCGG 
CAGCCCTGTG GCCGCTTCCT CCGCGCCTAC CGCGAGGGGG CGCTGCGCGC CGCGCTGCAG 
AGGAGCCTGG CGGCCGCGCT CGCCCAGCAC TCGGTGCCGC TGCAACTGGA GCTGCGCGCC 
GGCGCCGAGC GGCTGGACGC TTTGCTGGCG GACGAGGAGC GCTGTTTGAG TTGCATCCTA 
GCCCAGCAGC CCGACCGGCT CCGGGATGAA GAACTGGCTG AGCTGGAGGA TGCGCTGCGA 
AATCTGAAGT GCGGCTCGGG GGCCCGGGGT GGCGACGGGG AGGTCGCTTC GGCCCCCTTG 
CAGCCCCCGG TGCCCTCTCT GTCGGAGGTG AAGCCGCCGC CGCCGCCGCC ACCTGCCCAG 
ACTTTTCTGT TCCAGGGTCA GCCTGTAGTG AATCGGCCGC TGAGCCTGAA GGACCAACAG 
ACGTTCGCGC GCTCTGTGGG TCTCAAATGG CGCAAGGTGG GGCGCTCACT GCAGCGAGGC 
TGCCGGGCGC TGCGGGACCC GGCGCTGGAC TCGCTGGCCT ACGAGTACGA GCGCGAGGGA 
CTGTACGAGC AGGCCTTCCA GCTGCTGCGG CGCTTCGTGC AGGCCGAGGG CCGCCGCGCC 
ACGCTGCAGC GCCTGGTGGA GGCACTCGAG GAGAACGAGC TCACCAGCCT GGCAGAGGAC 
TTGCTGGGCC TGACCGATCC CAATGGCGGC CTGGCCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005256270.1
CDS	778..1536
Translation	MLKIHRSDPQLIVQLRFCGRQPCGRFLRAYREGALRAALQRSLAAALAQHSVPLQLELRAGAERLDALLADEERCLSCILAQQPDRLRDEELAELEDALRNLKCGSGARGGDGEVASAPLQPPVPSLSEVKPPPPPPPAQTFLFQGQPVVNRPLSLKDQQTFARSVGLKWRKVGRSLQRGCRALRDPALDSLAYEYEREGLYEQAFQLLRRFVQAEGRRATLQRLVEALEENELTSLAEDLLGLTDPNGGLA

Target ORF information:

RefSeq Version	XM_005256213.3
Organism	Homo sapiens(human)
Definition	Homo sapiens TNFRSF1A associated via death domain (TRADD), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005256213.3

ORF Insert Sequence:

ATGCTGAAGA TCCACCGCAG CGACCCGCAG CTGATCGTGC AGCTGCGATT CTGCGGGCGG 
CAGCCCTGTG GCCGCTTCCT CCGCGCCTAC CGCGAGGGGG CGCTGCGCGC CGCGCTGCAG 
AGGAGCCTGG CGGCCGCGCT CGCCCAGCAC TCGGTGCCGC TGCAACTGGA GCTGCGCGCC 
GGCGCCGAGC GGCTGGACGC TTTGCTGGCG GACGAGGAGC GCTGTTTGAG TTGCATCCTA 
GCCCAGCAGC CCGACCGGCT CCGGGATGAA GAACTGGCTG AGCTGGAGGA TGCGCTGCGA 
AATCTGAAGT GCGGCTCGGG GGCCCGGGGT GGCGACGGGG AGGTCGCTTC GGCCCCCTTG 
CAGCCCCCGG TGCCCTCTCT GTCGGAGGTG AAGCCGCCGC CGCCGCCGCC ACCTGCCCAG 
ACTTTTCTGT TCCAGGGTCA GCCTGTAGTG AATCGGCCGC TGAGCCTGAA GGACCAACAG 
ACGTTCGCGC GCTCTGTGGG TCTCAAATGG CGCAAGGTGG GGCGCTCACT GCAGCGAGGC 
TGCCGGGCGC TGCGGGACCC GGCGCTGGAC TCGCTGGCCT ACGAGTACGA GCGCGAGGGA 
CTGTACGAGC AGGCCTTCCA GCTGCTGCGG CGCTTCGTGC AGGCCGAGGG CCGCCGCGCC 
ACGCTGCAGC GCCTGGTGGA GGCACTCGAG GAGAACGAGC TCACCAGCCT GGCAGAGGAC 
TTGCTGGGCC TGACCGATCC CAATGGCGGC CTGGCCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TRADD ( XM_005256213.4 ) cDNA ORF clone, Homo sapiens(human) -> XP_005256270.1 Homo sapiens TNFRSF1A associated via death domain (TRADD), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu49561
Clone ID Related Accession (Same CDS sequence)	XM_005256213.3 , XM_005256213.4
Accession Version	XM_005256213.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 759bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	tumor necrosis factor receptor type 1-associated DEATH domain protein isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000016.10) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_005256213.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCTGAAGA TCCACCGCAG CGACCCGCAG CTGATCGTGC AGCTGCGATT CTGCGGGCGG 
CAGCCCTGTG GCCGCTTCCT CCGCGCCTAC CGCGAGGGGG CGCTGCGCGC CGCGCTGCAG 
AGGAGCCTGG CGGCCGCGCT CGCCCAGCAC TCGGTGCCGC TGCAACTGGA GCTGCGCGCC 
GGCGCCGAGC GGCTGGACGC TTTGCTGGCG GACGAGGAGC GCTGTTTGAG TTGCATCCTA 
GCCCAGCAGC CCGACCGGCT CCGGGATGAA GAACTGGCTG AGCTGGAGGA TGCGCTGCGA 
AATCTGAAGT GCGGCTCGGG GGCCCGGGGT GGCGACGGGG AGGTCGCTTC GGCCCCCTTG 
CAGCCCCCGG TGCCCTCTCT GTCGGAGGTG AAGCCGCCGC CGCCGCCGCC ACCTGCCCAG 
ACTTTTCTGT TCCAGGGTCA GCCTGTAGTG AATCGGCCGC TGAGCCTGAA GGACCAACAG 
ACGTTCGCGC GCTCTGTGGG TCTCAAATGG CGCAAGGTGG GGCGCTCACT GCAGCGAGGC 
TGCCGGGCGC TGCGGGACCC GGCGCTGGAC TCGCTGGCCT ACGAGTACGA GCGCGAGGGA 
CTGTACGAGC AGGCCTTCCA GCTGCTGCGG CGCTTCGTGC AGGCCGAGGG CCGCCGCGCC 
ACGCTGCAGC GCCTGGTGGA GGCACTCGAG GAGAACGAGC TCACCAGCCT GGCAGAGGAC 
TTGCTGGGCC TGACCGATCC CAATGGCGGC CTGGCCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005256270.1
CDS	801..1559
Translation	MLKIHRSDPQLIVQLRFCGRQPCGRFLRAYREGALRAALQRSLAAALAQHSVPLQLELRAGAERLDALLADEERCLSCILAQQPDRLRDEELAELEDALRNLKCGSGARGGDGEVASAPLQPPVPSLSEVKPPPPPPPAQTFLFQGQPVVNRPLSLKDQQTFARSVGLKWRKVGRSLQRGCRALRDPALDSLAYEYEREGLYEQAFQLLRRFVQAEGRRATLQRLVEALEENELTSLAEDLLGLTDPNGGLA

Target ORF information:

RefSeq Version	XM_005256213.4
Organism	Homo sapiens(human)
Definition	Homo sapiens TNFRSF1A associated via death domain (TRADD), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005256213.4

ORF Insert Sequence:

ATGCTGAAGA TCCACCGCAG CGACCCGCAG CTGATCGTGC AGCTGCGATT CTGCGGGCGG 
CAGCCCTGTG GCCGCTTCCT CCGCGCCTAC CGCGAGGGGG CGCTGCGCGC CGCGCTGCAG 
AGGAGCCTGG CGGCCGCGCT CGCCCAGCAC TCGGTGCCGC TGCAACTGGA GCTGCGCGCC 
GGCGCCGAGC GGCTGGACGC TTTGCTGGCG GACGAGGAGC GCTGTTTGAG TTGCATCCTA 
GCCCAGCAGC CCGACCGGCT CCGGGATGAA GAACTGGCTG AGCTGGAGGA TGCGCTGCGA 
AATCTGAAGT GCGGCTCGGG GGCCCGGGGT GGCGACGGGG AGGTCGCTTC GGCCCCCTTG 
CAGCCCCCGG TGCCCTCTCT GTCGGAGGTG AAGCCGCCGC CGCCGCCGCC ACCTGCCCAG 
ACTTTTCTGT TCCAGGGTCA GCCTGTAGTG AATCGGCCGC TGAGCCTGAA GGACCAACAG 
ACGTTCGCGC GCTCTGTGGG TCTCAAATGG CGCAAGGTGG GGCGCTCACT GCAGCGAGGC 
TGCCGGGCGC TGCGGGACCC GGCGCTGGAC TCGCTGGCCT ACGAGTACGA GCGCGAGGGA 
CTGTACGAGC AGGCCTTCCA GCTGCTGCGG CGCTTCGTGC AGGCCGAGGG CCGCCGCGCC 
ACGCTGCAGC GCCTGGTGGA GGCACTCGAG GAGAACGAGC TCACCAGCCT GGCAGAGGAC 
TTGCTGGGCC TGACCGATCC CAATGGCGGC CTGGCCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Identification of TRADD as a potential biomarker in human uterine leiomyoma through iTRAQ based proteomic profiling.
Molecular and cellular probes3615-20(2017 Dec)
Liu Y,Lu D,Sheng J,Luo L,Zhang W

Structure of the C-terminal domain of TRADD reveals a novel fold in the death domain superfamily.
Scientific reports7(1)7073(2017 Aug)
Zhang N,Yuan W,Fan JS,Lin Z

TRADD, TRAF2, RIP1 and TAK1 are required for TNF-?-induced pro-labour mediators in human primary myometrial cells.
American journal of reproductive immunology (New York, N.Y. : 1989)78(1)(2017 Jul)
Lim R,Barker G,Lappas M

Nuclear TRADD prevents DNA damage-mediated death by facilitating non-homologous end-joining repair.
Scientific reports7(1)3332(2017 Jun)
Koo GB,Ji JH,Cho H,Morgan MJ,Kim YS

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TRADD cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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