CBL cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	CBL
Entrez Gene ID	867
Full Name	Cbl proto-oncogene
Synonyms	C-CBL,CBL2,FRA11B,NSLL,RNF55
General protein information	Preferred Names Cbl proto-oncogene Names E3 ubiquitin-protein ligase CBL Cas-Br-M (murine) ecotropic retroviral transforming sequence Cbl proto-oncogene, E3 ubiquitin protein ligase RING finger protein 55 RING-type E3 ubiquitin transferase CBL casitas B-lineage lymphoma proto-oncogene fragile site, folic acid type, rare, fra(11)(q23.3) oncogene CBL2 proto-oncogene c-Cbl signal transduction protein CBL
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 11 Map Location: 11q23.3
Summary	This gene is a proto-oncogene that encodes a RING finger E3 ubiquitin ligase. The encoded protein is one of the enzymes required for targeting substrates for degradation by the proteasome. This protein mediates the transfer of ubiquitin from ubiquitin conjugating enzymes (E2) to specific substrates. This protein also contains an N-terminal phosphotyrosine binding domain that allows it to interact with numerous tyrosine-phosphorylated substrates and target them for proteasome degradation. As such it functions as a negative regulator of many signal transduction pathways. This gene has been found to be mutated or translocated in many cancers including acute myeloid leukaemia, and expansion of CGG repeats in the 5' UTR has been associated with Jacobsen syndrome. Mutations in this gene are also the cause of Noonan syndrome-like disorder. [provided by RefSeq, Jul 2016].
Disorder MIM:	165360
Disorder Html:	Noonan syndrome-like disorder with or without juvenile myelomonocytic leukemia, 613563 (3); ?Juvenile myelomonocytic leukemia, 607785 (3)

mRNA and Protein(s)

mRNA	Protein	Name
XM_011543057.2	XP_011541359.1	E3 ubiquitin-protein ligase CBL isoform X2
XM_017018511.1	XP_016874000.1	E3 ubiquitin-protein ligase CBL isoform X1
NM_005188.3	NP_005179.2	E3 ubiquitin-protein ligase CBL
NM_005188.4	NP_005179.2	E3 ubiquitin-protein ligase CBL

Pathways from BioSystems

Homologies

Gallus gallus (chicken)	CBL	NP_989539.1
	CBL	XP_001104812.1
Xenopus tropicalis (tropical clawed frog)	cbl	NP_001122110.1
Pan troglodytes (chimpanzee)	CBL	XP_001165648.1
Mus musculus (house mouse)	Cbl	NP_031645.2
Homo sapiens (human)	CBL	NP_005179.2
Canis lupus familiaris (dog)	CBL	XP_546487.3
Bos taurus (cattle)	CBL	XP_002693128.2
Rattus norvegicus (Norway rat)	Cbl	XP_576396.3
Danio rerio (zebrafish)	cbl	NP_001007331.1

Gene Ontology

The following CBL gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the CBL cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu21115	NM_005188.4 Latest version!	Homo sapiens Cbl proto-oncogene (CBL), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
OHu56677	XM_011543057.2 Latest version!	Homo sapiens Cbl proto-oncogene (CBL), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
OHu92650	XM_017018511.1 Latest version!	Homo sapiens Cbl proto-oncogene (CBL), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	10-12	$391.30 $559.00
View Old Accession Versions >>
OHu21115	NM_005188.3	Homo sapiens Cbl proto-oncogene (CBL), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

CBL ( NM_005188.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_005179.2 Homo sapiens Cbl proto-oncogene (CBL), mRNA.

Price & Availability↑

CloneID	OHu21115
Clone ID Related Accession (Same CDS sequence)	NM_005188.3 , NM_005188.4
Accession Version	NM_005188.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2721bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-06-25
Organism	Homo sapiens(human)
Product	E3 ubiquitin-protein ligase CBL
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DB457271.2, BC132733.1, AP002956.1 and AA806454.1. This sequence is a reference standard in the RefSeqGene project. On Mar 7, 2012 this sequence version replaced NM_005188.2. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC132733.1, SRR1803616.164251.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGCCGGCA ACGTGAAGAA GAGCTCTGGG GCCGGGGGCG GCAGCGGCTC CGGGGGCTCG 
GGTTCGGGTG GCCTGATTGG GCTCATGAAG GACGCCTTCC AGCCGCACCA CCACCACCAC 
CACCACCTCA GCCCCCACCC GCCGGGGACG GTGGACAAGA AGATGGTGGA GAAGTGCTGG 
AAGCTCATGG ACAAGGTGGT GCGGTTGTGT CAGAACCCAA AGCTGGCGCT AAAGAATAGC 
CCACCTTATA TCTTAGACCT GCTACCAGAT ACCTACCAGC ATCTCCGTAC TATCTTGTCA 
AGATATGAGG GGAAGATGGA GACACTTGGA GAAAATGAGT ATTTTAGGGT GTTTATGGAG 
AATTTGATGA AGAAAACTAA GCAAACCATA AGCCTCTTCA AGGAGGGAAA AGAAAGAATG 
TATGAGGAGA ATTCTCAGCC TAGGCGAAAC CTAACCAAAC TGTCCCTCAT CTTCAGCCAC 
ATGCTGGCAG AACTAAAAGG AATCTTTCCA AGTGGACTCT TTCAGGGAGA CACATTTCGG 
ATTACTAAAG CAGATGCTGC GGAATTTTGG AGAAAAGCTT TTGGGGAAAA GACAATAGTC 
CCTTGGAAGA GCTTTCGACA GGCTCTACAT GAAGTGCATC CCATCAGTTC TGGGCTGGAG 
GCCATGGCTC TGAAATCCAC TATTGATCTG ACCTGCAATG ATTATATTTC GGTTTTTGAA 
TTTGACATCT TTACCCGACT CTTTCAGCCC TGGTCCTCTT TGCTCAGGAA TTGGAACAGC 
CTTGCTGTAA CTCATCCTGG CTACATGGCT TTTTTGACGT ATGACGAAGT GAAAGCTCGG 
CTCCAGAAAT TCATTCACAA ACCTGGCAGT TATATCTTCC GGCTGAGCTG TACTCGTCTG 
GGTCAGTGGG CTATTGGGTA TGTTACTGCT GATGGGAACA TTCTCCAGAC AATCCCTCAC 
AATAAACCTC TCTTCCAAGC ACTGATTGAT GGCTTCAGGG AAGGCTTCTA TTTGTTTCCT 
GATGGACGAA ATCAGAATCC TGATCTGACT GGCTTATGTG AACCAACTCC CCAAGACCAT 
ATCAAAGTGA CCCAGGAACA ATATGAATTA TACTGTGAGA TGGGCTCCAC ATTCCAACTA 
TGTAAAATAT GTGCTGAAAA TGATAAGGAT GTAAAGATTG AGCCCTGTGG ACACCTCATG 
TGCACATCCT GTCTTACATC CTGGCAGGAA TCAGAAGGTC AGGGCTGTCC TTTCTGCCGA 
TGTGAAATTA AAGGTACTGA ACCCATCGTG GTAGATCCGT TTGATCCTAG AGGGAGTGGC 
AGCCTGTTGA GGCAAGGAGC AGAGGGAGCT CCCTCCCCAA ATTATGATGA TGATGATGAT 
GAACGAGCTG ATGATACTCT CTTCATGATG AAGGAATTGG CTGGTGCCAA GGTGGAACGG 
CCGCCTTCTC CATTCTCCAT GGCCCCACAA GCTTCCCTTC CCCCGGTGCC ACCACGACTT 
GACCTTCTGC CGCAGCGAGT ATGTGTTCCC TCAAGTGCTT CTGCTCTTGG AACTGCTTCT 
AAGGCTGCTT CTGGCTCCCT TCATAAAGAC AAACCATTGC CAGTACCTCC CACACTTCGA 
GATCTTCCAC CACCACCGCC TCCAGACCGG CCATATTCTG TTGGAGCAGA ATCCCGACCT 
CAAAGACGCC CCTTGCCTTG TACACCAGGC GACTGTCCCT CCAGAGACAA ACTGCCCCCT 
GTCCCCTCTA GCCGCCTTGG AGACTCATGG CTGCCCCGGC CAATCCCCAA AGTACCAGTA 
TCTGCCCCAA GTTCCAGTGA TCCCTGGACA GGAAGAGAAT TAACCAACCG GCACTCACTT 
CCATTTTCAT TGCCCTCACA AATGGAGCCC AGACCAGATG TGCCTAGGCT CGGAAGCACG 
TTCAGTCTGG ATACCTCCAT GAGTATGAAT AGCAGCCCAT TAGTAGGTCC AGAGTGTGAC 
CACCCCAAAA TCAAACCTTC CTCATCTGCC AATGCCATTT ATTCTCTGGC TGCCAGACCT 
CTTCCTGTGC CAAAACTGCC ACCTGGGGAG CAATGTGAGG GTGAAGAGGA CACAGAGTAC 
ATGACTCCCT CTTCCAGGCC TCTACGGCCT TTGGATACAT CCCAGAGTTC ACGAGCATGT 
GATTGCGACC AGCAGATTGA TAGCTGTACG TATGAAGCAA TGTATAATAT TCAGTCCCAG 
GCGCCATCTA TCACCGAGAG CAGCACCTTT GGTGAAGGGA ATTTGGCCGC AGCCCATGCC 
AACACTGGTC CCGAGGAGTC AGAAAATGAG GATGATGGGT ATGATGTCCC AAAGCCACCT 
GTGCCGGCCG TGCTGGCCCG CCGAACTCTC TCAGATATCT CTAATGCCAG CTCCTCCTTT 
GGCTGGTTGT CTCTGGATGG TGATCCTACA ACAAATGTCA CTGAAGGTTC CCAAGTTCCC 
GAGAGGCCTC CAAAACCATT CCCGCGGAGA ATCAACTCTG AACGGAAAGC TGGCAGCTGT 
CAGCAAGGTA GTGGTCCTGC CGCCTCTGCT GCCACCGCCT CACCTCAGCT CTCCAGTGAG 
ATCGAGAACC TCATGAGTCA GGGGTACTCC TACCAGGACA TCCAGAAAGC TTTGGTCATT 
GCCCAGAACA ACATCGAGAT GGCCAAAAAC ATCCTCCGGG AATTTGTTTC CATTTCTTCT 
CCTGCCCATG TAGCTACCTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_005179.2
CDS	143..2863
Translation	MAGNVKKSSGAGGGSGSGGSGSGGLIGLMKDAFQPHHHHHHHLSPHPPGTVDKKMVEKCWKLMDKVVRLCQNPKLALKNSPPYILDLLPDTYQHLRTILSRYEGKMETLGENEYFRVFMENLMKKTKQTISLFKEGKERMYEENSQPRRNLTKLSLIFSHMLAELKGIFPSGLFQGDTFRITKADAAEFWRKAFGEKTIVPWKSFRQALHEVHPISSGLEAMALKSTIDLTCNDYISVFEFDIFTRLFQPWSSLLRNWNSLAVTHPGYMAFLTYDEVKARLQKFIHKPGSYIFRLSCTRLGQWAIGYVTADGNILQTIPHNKPLFQALIDGFREGFYLFPDGRNQNPDLTGLCEPTPQDHIKVTQEQYELYCEMGSTFQLCKICAENDKDVKIEPCGHLMCTSCLTSWQESEGQGCPFCRCEIKGTEPIVVDPFDPRGSGSLLRQGAEGAPSPNYDDDDDERADDTLFMMKELAGAKVERPPSPFSMAPQASLPPVPPRLDLLPQRVCVPSSASALGTASKAASGSLHKDKPLPVPPTLRDLPPPPPPDRPYSVGAESRPQRRPLPCTPGDCPSRDKLPPVPSSRLGDSWLPRPIPKVPVSAPSSSDPWTGRELTNRHSLPFSLPSQMEPRPDVPRLGSTFSLDTSMSMNSSPLVGPECDHPKIKPSSSANAIYSLAARPLPVPKLPPGEQCEGEEDTEYMTPSSRPLRPLDTSQSSRACDCDQQIDSCTYEAMYNIQSQAPSITESSTFGEGNLAAAHANTGPEESENEDDGYDVPKPPVPAVLARRTLSDISNASSSFGWLSLDGDPTTNVTEGSQVPERPPKPFPRRINSERKAGSCQQGSGPAASAATASPQLSSEIENLMSQGYSYQDIQKALVIAQNNIEMAKNILREFVSISSPAHVAT

Target ORF information:

RefSeq Version	NM_005188.3
Organism	Homo sapiens(human)
Definition	Homo sapiens Cbl proto-oncogene (CBL), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_005188.3

ORF Insert Sequence:

ATGGCCGGCA ACGTGAAGAA GAGCTCTGGG GCCGGGGGCG GCAGCGGCTC CGGGGGCTCG 
GGTTCGGGTG GCCTGATTGG GCTCATGAAG GACGCCTTCC AGCCGCACCA CCACCACCAC 
CACCACCTCA GCCCCCACCC GCCGGGGACG GTGGACAAGA AGATGGTGGA GAAGTGCTGG 
AAGCTCATGG ACAAGGTGGT GCGGTTGTGT CAGAACCCAA AGCTGGCGCT AAAGAATAGC 
CCACCTTATA TCTTAGACCT GCTACCAGAT ACCTACCAGC ATCTCCGTAC TATCTTGTCA 
AGATATGAGG GGAAGATGGA GACACTTGGA GAAAATGAGT ATTTTAGGGT GTTTATGGAG 
AATTTGATGA AGAAAACTAA GCAAACCATA AGCCTCTTCA AGGAGGGAAA AGAAAGAATG 
TATGAGGAGA ATTCTCAGCC TAGGCGAAAC CTAACCAAAC TGTCCCTCAT CTTCAGCCAC 
ATGCTGGCAG AACTAAAAGG AATCTTTCCA AGTGGACTCT TTCAGGGAGA CACATTTCGG 
ATTACTAAAG CAGATGCTGC GGAATTTTGG AGAAAAGCTT TTGGGGAAAA GACAATAGTC 
CCTTGGAAGA GCTTTCGACA GGCTCTACAT GAAGTGCATC CCATCAGTTC TGGGCTGGAG 
GCCATGGCTC TGAAATCCAC TATTGATCTG ACCTGCAATG ATTATATTTC GGTTTTTGAA 
TTTGACATCT TTACCCGACT CTTTCAGCCC TGGTCCTCTT TGCTCAGGAA TTGGAACAGC 
CTTGCTGTAA CTCATCCTGG CTACATGGCT TTTTTGACGT ATGACGAAGT GAAAGCTCGG 
CTCCAGAAAT TCATTCACAA ACCTGGCAGT TATATCTTCC GGCTGAGCTG TACTCGTCTG 
GGTCAGTGGG CTATTGGGTA TGTTACTGCT GATGGGAACA TTCTCCAGAC AATCCCTCAC 
AATAAACCTC TCTTCCAAGC ACTGATTGAT GGCTTCAGGG AAGGCTTCTA TTTGTTTCCT 
GATGGACGAA ATCAGAATCC TGATCTGACT GGCTTATGTG AACCAACTCC CCAAGACCAT 
ATCAAAGTGA CCCAGGAACA ATATGAATTA TACTGTGAGA TGGGCTCCAC ATTCCAACTA 
TGTAAAATAT GTGCTGAAAA TGATAAGGAT GTAAAGATTG AGCCCTGTGG ACACCTCATG 
TGCACATCCT GTCTTACATC CTGGCAGGAA TCAGAAGGTC AGGGCTGTCC TTTCTGCCGA 
TGTGAAATTA AAGGTACTGA ACCCATCGTG GTAGATCCGT TTGATCCTAG AGGGAGTGGC 
AGCCTGTTGA GGCAAGGAGC AGAGGGAGCT CCCTCCCCAA ATTATGATGA TGATGATGAT 
GAACGAGCTG ATGATACTCT CTTCATGATG AAGGAATTGG CTGGTGCCAA GGTGGAACGG 
CCGCCTTCTC CATTCTCCAT GGCCCCACAA GCTTCCCTTC CCCCGGTGCC ACCACGACTT 
GACCTTCTGC CGCAGCGAGT ATGTGTTCCC TCAAGTGCTT CTGCTCTTGG AACTGCTTCT 
AAGGCTGCTT CTGGCTCCCT TCATAAAGAC AAACCATTGC CAGTACCTCC CACACTTCGA 
GATCTTCCAC CACCACCGCC TCCAGACCGG CCATATTCTG TTGGAGCAGA ATCCCGACCT 
CAAAGACGCC CCTTGCCTTG TACACCAGGC GACTGTCCCT CCAGAGACAA ACTGCCCCCT 
GTCCCCTCTA GCCGCCTTGG AGACTCATGG CTGCCCCGGC CAATCCCCAA AGTACCAGTA 
TCTGCCCCAA GTTCCAGTGA TCCCTGGACA GGAAGAGAAT TAACCAACCG GCACTCACTT 
CCATTTTCAT TGCCCTCACA AATGGAGCCC AGACCAGATG TGCCTAGGCT CGGAAGCACG 
TTCAGTCTGG ATACCTCCAT GAGTATGAAT AGCAGCCCAT TAGTAGGTCC AGAGTGTGAC 
CACCCCAAAA TCAAACCTTC CTCATCTGCC AATGCCATTT ATTCTCTGGC TGCCAGACCT 
CTTCCTGTGC CAAAACTGCC ACCTGGGGAG CAATGTGAGG GTGAAGAGGA CACAGAGTAC 
ATGACTCCCT CTTCCAGGCC TCTACGGCCT TTGGATACAT CCCAGAGTTC ACGAGCATGT 
GATTGCGACC AGCAGATTGA TAGCTGTACG TATGAAGCAA TGTATAATAT TCAGTCCCAG 
GCGCCATCTA TCACCGAGAG CAGCACCTTT GGTGAAGGGA ATTTGGCCGC AGCCCATGCC 
AACACTGGTC CCGAGGAGTC AGAAAATGAG GATGATGGGT ATGATGTCCC AAAGCCACCT 
GTGCCGGCCG TGCTGGCCCG CCGAACTCTC TCAGATATCT CTAATGCCAG CTCCTCCTTT 
GGCTGGTTGT CTCTGGATGG TGATCCTACA ACAAATGTCA CTGAAGGTTC CCAAGTTCCC 
GAGAGGCCTC CAAAACCATT CCCGCGGAGA ATCAACTCTG AACGGAAAGC TGGCAGCTGT 
CAGCAAGGTA GTGGTCCTGC CGCCTCTGCT GCCACCGCCT CACCTCAGCT CTCCAGTGAG 
ATCGAGAACC TCATGAGTCA GGGGTACTCC TACCAGGACA TCCAGAAAGC TTTGGTCATT 
GCCCAGAACA ACATCGAGAT GGCCAAAAAC ATCCTCCGGG AATTTGTTTC CATTTCTTCT 
CCTGCCCATG TAGCTACCTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CBL ( NM_005188.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_005179.2 Homo sapiens Cbl proto-oncogene (CBL), mRNA.

Price & Availability↑

CloneID	OHu21115
Clone ID Related Accession (Same CDS sequence)	NM_005188.3 , NM_005188.4
Accession Version	NM_005188.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2721bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-14
Organism	Homo sapiens(human)
Product	E3 ubiquitin-protein ligase CBL
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DB457271.2, BC132733.1, AP002956.1 and AA806454.1. On Aug 31, 2019 this sequence version replaced NM_005188.3. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC132733.1, X57110.1 [ECO:0000332] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGCCGGCA ACGTGAAGAA GAGCTCTGGG GCCGGGGGCG GCAGCGGCTC CGGGGGCTCG 
GGTTCGGGTG GCCTGATTGG GCTCATGAAG GACGCCTTCC AGCCGCACCA CCACCACCAC 
CACCACCTCA GCCCCCACCC GCCGGGGACG GTGGACAAGA AGATGGTGGA GAAGTGCTGG 
AAGCTCATGG ACAAGGTGGT GCGGTTGTGT CAGAACCCAA AGCTGGCGCT AAAGAATAGC 
CCACCTTATA TCTTAGACCT GCTACCAGAT ACCTACCAGC ATCTCCGTAC TATCTTGTCA 
AGATATGAGG GGAAGATGGA GACACTTGGA GAAAATGAGT ATTTTAGGGT GTTTATGGAG 
AATTTGATGA AGAAAACTAA GCAAACCATA AGCCTCTTCA AGGAGGGAAA AGAAAGAATG 
TATGAGGAGA ATTCTCAGCC TAGGCGAAAC CTAACCAAAC TGTCCCTCAT CTTCAGCCAC 
ATGCTGGCAG AACTAAAAGG AATCTTTCCA AGTGGACTCT TTCAGGGAGA CACATTTCGG 
ATTACTAAAG CAGATGCTGC GGAATTTTGG AGAAAAGCTT TTGGGGAAAA GACAATAGTC 
CCTTGGAAGA GCTTTCGACA GGCTCTACAT GAAGTGCATC CCATCAGTTC TGGGCTGGAG 
GCCATGGCTC TGAAATCCAC TATTGATCTG ACCTGCAATG ATTATATTTC GGTTTTTGAA 
TTTGACATCT TTACCCGACT CTTTCAGCCC TGGTCCTCTT TGCTCAGGAA TTGGAACAGC 
CTTGCTGTAA CTCATCCTGG CTACATGGCT TTTTTGACGT ATGACGAAGT GAAAGCTCGG 
CTCCAGAAAT TCATTCACAA ACCTGGCAGT TATATCTTCC GGCTGAGCTG TACTCGTCTG 
GGTCAGTGGG CTATTGGGTA TGTTACTGCT GATGGGAACA TTCTCCAGAC AATCCCTCAC 
AATAAACCTC TCTTCCAAGC ACTGATTGAT GGCTTCAGGG AAGGCTTCTA TTTGTTTCCT 
GATGGACGAA ATCAGAATCC TGATCTGACT GGCTTATGTG AACCAACTCC CCAAGACCAT 
ATCAAAGTGA CCCAGGAACA ATATGAATTA TACTGTGAGA TGGGCTCCAC ATTCCAACTA 
TGTAAAATAT GTGCTGAAAA TGATAAGGAT GTAAAGATTG AGCCCTGTGG ACACCTCATG 
TGCACATCCT GTCTTACATC CTGGCAGGAA TCAGAAGGTC AGGGCTGTCC TTTCTGCCGA 
TGTGAAATTA AAGGTACTGA ACCCATCGTG GTAGATCCGT TTGATCCTAG AGGGAGTGGC 
AGCCTGTTGA GGCAAGGAGC AGAGGGAGCT CCCTCCCCAA ATTATGATGA TGATGATGAT 
GAACGAGCTG ATGATACTCT CTTCATGATG AAGGAATTGG CTGGTGCCAA GGTGGAACGG 
CCGCCTTCTC CATTCTCCAT GGCCCCACAA GCTTCCCTTC CCCCGGTGCC ACCACGACTT 
GACCTTCTGC CGCAGCGAGT ATGTGTTCCC TCAAGTGCTT CTGCTCTTGG AACTGCTTCT 
AAGGCTGCTT CTGGCTCCCT TCATAAAGAC AAACCATTGC CAGTACCTCC CACACTTCGA 
GATCTTCCAC CACCACCGCC TCCAGACCGG CCATATTCTG TTGGAGCAGA ATCCCGACCT 
CAAAGACGCC CCTTGCCTTG TACACCAGGC GACTGTCCCT CCAGAGACAA ACTGCCCCCT 
GTCCCCTCTA GCCGCCTTGG AGACTCATGG CTGCCCCGGC CAATCCCCAA AGTACCAGTA 
TCTGCCCCAA GTTCCAGTGA TCCCTGGACA GGAAGAGAAT TAACCAACCG GCACTCACTT 
CCATTTTCAT TGCCCTCACA AATGGAGCCC AGACCAGATG TGCCTAGGCT CGGAAGCACG 
TTCAGTCTGG ATACCTCCAT GAGTATGAAT AGCAGCCCAT TAGTAGGTCC AGAGTGTGAC 
CACCCCAAAA TCAAACCTTC CTCATCTGCC AATGCCATTT ATTCTCTGGC TGCCAGACCT 
CTTCCTGTGC CAAAACTGCC ACCTGGGGAG CAATGTGAGG GTGAAGAGGA CACAGAGTAC 
ATGACTCCCT CTTCCAGGCC TCTACGGCCT TTGGATACAT CCCAGAGTTC ACGAGCATGT 
GATTGCGACC AGCAGATTGA TAGCTGTACG TATGAAGCAA TGTATAATAT TCAGTCCCAG 
GCGCCATCTA TCACCGAGAG CAGCACCTTT GGTGAAGGGA ATTTGGCCGC AGCCCATGCC 
AACACTGGTC CCGAGGAGTC AGAAAATGAG GATGATGGGT ATGATGTCCC AAAGCCACCT 
GTGCCGGCCG TGCTGGCCCG CCGAACTCTC TCAGATATCT CTAATGCCAG CTCCTCCTTT 
GGCTGGTTGT CTCTGGATGG TGATCCTACA ACAAATGTCA CTGAAGGTTC CCAAGTTCCC 
GAGAGGCCTC CAAAACCATT CCCGCGGAGA ATCAACTCTG AACGGAAAGC TGGCAGCTGT 
CAGCAAGGTA GTGGTCCTGC CGCCTCTGCT GCCACCGCCT CACCTCAGCT CTCCAGTGAG 
ATCGAGAACC TCATGAGTCA GGGGTACTCC TACCAGGACA TCCAGAAAGC TTTGGTCATT 
GCCCAGAACA ACATCGAGAT GGCCAAAAAC ATCCTCCGGG AATTTGTTTC CATTTCTTCT 
CCTGCCCATG TAGCTACCTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_005179.2
CDS	80..2800
Translation	MAGNVKKSSGAGGGSGSGGSGSGGLIGLMKDAFQPHHHHHHHLSPHPPGTVDKKMVEKCWKLMDKVVRLCQNPKLALKNSPPYILDLLPDTYQHLRTILSRYEGKMETLGENEYFRVFMENLMKKTKQTISLFKEGKERMYEENSQPRRNLTKLSLIFSHMLAELKGIFPSGLFQGDTFRITKADAAEFWRKAFGEKTIVPWKSFRQALHEVHPISSGLEAMALKSTIDLTCNDYISVFEFDIFTRLFQPWSSLLRNWNSLAVTHPGYMAFLTYDEVKARLQKFIHKPGSYIFRLSCTRLGQWAIGYVTADGNILQTIPHNKPLFQALIDGFREGFYLFPDGRNQNPDLTGLCEPTPQDHIKVTQEQYELYCEMGSTFQLCKICAENDKDVKIEPCGHLMCTSCLTSWQESEGQGCPFCRCEIKGTEPIVVDPFDPRGSGSLLRQGAEGAPSPNYDDDDDERADDTLFMMKELAGAKVERPPSPFSMAPQASLPPVPPRLDLLPQRVCVPSSASALGTASKAASGSLHKDKPLPVPPTLRDLPPPPPPDRPYSVGAESRPQRRPLPCTPGDCPSRDKLPPVPSSRLGDSWLPRPIPKVPVSAPSSSDPWTGRELTNRHSLPFSLPSQMEPRPDVPRLGSTFSLDTSMSMNSSPLVGPECDHPKIKPSSSANAIYSLAARPLPVPKLPPGEQCEGEEDTEYMTPSSRPLRPLDTSQSSRACDCDQQIDSCTYEAMYNIQSQAPSITESSTFGEGNLAAAHANTGPEESENEDDGYDVPKPPVPAVLARRTLSDISNASSSFGWLSLDGDPTTNVTEGSQVPERPPKPFPRRINSERKAGSCQQGSGPAASAATASPQLSSEIENLMSQGYSYQDIQKALVIAQNNIEMAKNILREFVSISSPAHVAT

Target ORF information:

RefSeq Version	NM_005188.4
Organism	Homo sapiens(human)
Definition	Homo sapiens Cbl proto-oncogene (CBL), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_005188.4

ORF Insert Sequence:

ATGGCCGGCA ACGTGAAGAA GAGCTCTGGG GCCGGGGGCG GCAGCGGCTC CGGGGGCTCG 
GGTTCGGGTG GCCTGATTGG GCTCATGAAG GACGCCTTCC AGCCGCACCA CCACCACCAC 
CACCACCTCA GCCCCCACCC GCCGGGGACG GTGGACAAGA AGATGGTGGA GAAGTGCTGG 
AAGCTCATGG ACAAGGTGGT GCGGTTGTGT CAGAACCCAA AGCTGGCGCT AAAGAATAGC 
CCACCTTATA TCTTAGACCT GCTACCAGAT ACCTACCAGC ATCTCCGTAC TATCTTGTCA 
AGATATGAGG GGAAGATGGA GACACTTGGA GAAAATGAGT ATTTTAGGGT GTTTATGGAG 
AATTTGATGA AGAAAACTAA GCAAACCATA AGCCTCTTCA AGGAGGGAAA AGAAAGAATG 
TATGAGGAGA ATTCTCAGCC TAGGCGAAAC CTAACCAAAC TGTCCCTCAT CTTCAGCCAC 
ATGCTGGCAG AACTAAAAGG AATCTTTCCA AGTGGACTCT TTCAGGGAGA CACATTTCGG 
ATTACTAAAG CAGATGCTGC GGAATTTTGG AGAAAAGCTT TTGGGGAAAA GACAATAGTC 
CCTTGGAAGA GCTTTCGACA GGCTCTACAT GAAGTGCATC CCATCAGTTC TGGGCTGGAG 
GCCATGGCTC TGAAATCCAC TATTGATCTG ACCTGCAATG ATTATATTTC GGTTTTTGAA 
TTTGACATCT TTACCCGACT CTTTCAGCCC TGGTCCTCTT TGCTCAGGAA TTGGAACAGC 
CTTGCTGTAA CTCATCCTGG CTACATGGCT TTTTTGACGT ATGACGAAGT GAAAGCTCGG 
CTCCAGAAAT TCATTCACAA ACCTGGCAGT TATATCTTCC GGCTGAGCTG TACTCGTCTG 
GGTCAGTGGG CTATTGGGTA TGTTACTGCT GATGGGAACA TTCTCCAGAC AATCCCTCAC 
AATAAACCTC TCTTCCAAGC ACTGATTGAT GGCTTCAGGG AAGGCTTCTA TTTGTTTCCT 
GATGGACGAA ATCAGAATCC TGATCTGACT GGCTTATGTG AACCAACTCC CCAAGACCAT 
ATCAAAGTGA CCCAGGAACA ATATGAATTA TACTGTGAGA TGGGCTCCAC ATTCCAACTA 
TGTAAAATAT GTGCTGAAAA TGATAAGGAT GTAAAGATTG AGCCCTGTGG ACACCTCATG 
TGCACATCCT GTCTTACATC CTGGCAGGAA TCAGAAGGTC AGGGCTGTCC TTTCTGCCGA 
TGTGAAATTA AAGGTACTGA ACCCATCGTG GTAGATCCGT TTGATCCTAG AGGGAGTGGC 
AGCCTGTTGA GGCAAGGAGC AGAGGGAGCT CCCTCCCCAA ATTATGATGA TGATGATGAT 
GAACGAGCTG ATGATACTCT CTTCATGATG AAGGAATTGG CTGGTGCCAA GGTGGAACGG 
CCGCCTTCTC CATTCTCCAT GGCCCCACAA GCTTCCCTTC CCCCGGTGCC ACCACGACTT 
GACCTTCTGC CGCAGCGAGT ATGTGTTCCC TCAAGTGCTT CTGCTCTTGG AACTGCTTCT 
AAGGCTGCTT CTGGCTCCCT TCATAAAGAC AAACCATTGC CAGTACCTCC CACACTTCGA 
GATCTTCCAC CACCACCGCC TCCAGACCGG CCATATTCTG TTGGAGCAGA ATCCCGACCT 
CAAAGACGCC CCTTGCCTTG TACACCAGGC GACTGTCCCT CCAGAGACAA ACTGCCCCCT 
GTCCCCTCTA GCCGCCTTGG AGACTCATGG CTGCCCCGGC CAATCCCCAA AGTACCAGTA 
TCTGCCCCAA GTTCCAGTGA TCCCTGGACA GGAAGAGAAT TAACCAACCG GCACTCACTT 
CCATTTTCAT TGCCCTCACA AATGGAGCCC AGACCAGATG TGCCTAGGCT CGGAAGCACG 
TTCAGTCTGG ATACCTCCAT GAGTATGAAT AGCAGCCCAT TAGTAGGTCC AGAGTGTGAC 
CACCCCAAAA TCAAACCTTC CTCATCTGCC AATGCCATTT ATTCTCTGGC TGCCAGACCT 
CTTCCTGTGC CAAAACTGCC ACCTGGGGAG CAATGTGAGG GTGAAGAGGA CACAGAGTAC 
ATGACTCCCT CTTCCAGGCC TCTACGGCCT TTGGATACAT CCCAGAGTTC ACGAGCATGT 
GATTGCGACC AGCAGATTGA TAGCTGTACG TATGAAGCAA TGTATAATAT TCAGTCCCAG 
GCGCCATCTA TCACCGAGAG CAGCACCTTT GGTGAAGGGA ATTTGGCCGC AGCCCATGCC 
AACACTGGTC CCGAGGAGTC AGAAAATGAG GATGATGGGT ATGATGTCCC AAAGCCACCT 
GTGCCGGCCG TGCTGGCCCG CCGAACTCTC TCAGATATCT CTAATGCCAG CTCCTCCTTT 
GGCTGGTTGT CTCTGGATGG TGATCCTACA ACAAATGTCA CTGAAGGTTC CCAAGTTCCC 
GAGAGGCCTC CAAAACCATT CCCGCGGAGA ATCAACTCTG AACGGAAAGC TGGCAGCTGT 
CAGCAAGGTA GTGGTCCTGC CGCCTCTGCT GCCACCGCCT CACCTCAGCT CTCCAGTGAG 
ATCGAGAACC TCATGAGTCA GGGGTACTCC TACCAGGACA TCCAGAAAGC TTTGGTCATT 
GCCCAGAACA ACATCGAGAT GGCCAAAAAC ATCCTCCGGG AATTTGTTTC CATTTCTTCT 
CCTGCCCATG TAGCTACCTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CBL ( XM_011543057.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011541359.1 Homo sapiens Cbl proto-oncogene (CBL), transcript variant X2, mRNA.

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CloneID	OHu56677
Clone ID Related Accession (Same CDS sequence)	XM_011543057.2
Accession Version	XM_011543057.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1506bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	E3 ubiquitin-protein ligase CBL isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000011.10) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011543057.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCCGGCA ACGTGAAGAA GAGCTCTGGG GCCGGGGGCG GCAGCGGCTC CGGGGGCTCG 
GGTTCGGGTG GCCTGATTGG GCTCATGAAG GACGCCTTCC AGCCGCACCA CCACCACCAC 
CACCACCTCA GCCCCCACCC GCCGGGGACG GTGGACAAGA AGATGGTGGA GAAGTGCTGG 
AAGCTCATGG ACAAGGTGGT GCGGTTGTGT CAGAACCCAA AGCTGGCGCT AAAGAATAGC 
CCACCTTATA TCTTAGACCT GCTACCAGAT ACCTACCAGC ATCTCCGTAC TATCTTGTCA 
AGATATGAGG GGAAGATGGA GACACTTGGA GAAAATGAGT ATTTTAGGGT GTTTATGGAG 
AATTTGATGA AGAAAACTAA GCAAACCATA AGCCTCTTCA AGGAGGGAAA AGAAAGAATG 
TATGAGGAGA ATTCTCAGCC TAGGCGAAAC CTAACCAAAC TGTCCCTCAT CTTCAGCCAC 
ATGCTGGCAG AACTAAAAGG AATCTTTCCA AGTGGACTCT TTCAGGGAGA CACATTTCGG 
ATTACTAAAG CAGATGCTGC GGAATTTTGG AGAAAAGCTT TTGGGGAAAA GACAATAGTC 
CCTTGGAAGA GCTTTCGACA GGCTCTACAT GAAGTGCATC CCATCAGTTC TGGGCTGGAG 
GCCATGGCTC TGAAATCCAC TATTGATCTG ACCTGCAATG ATTATATTTC GGTTTTTGAA 
TTTGACATCT TTACCCGACT CTTTCAGCCC TGGTCCTCTT TGCTCAGGAA TTGGAACAGC 
CTTGCTGTAA CTCATCCTGG CTACATGGCT TTTTTGACGT ATGACGAAGT GAAAGCTCGG 
CTCCAGAAAT TCATTCACAA ACCTGGCAGT TATATCTTCC GGCTGAGCTG TACTCGTCTG 
GGTCAGTGGG CTATTGGGTA TGTTACTGCT GATGGGAACA TTCTCCAGAC AATCCCTCAC 
AATAAACCTC TCTTCCAAGC ACTGATTGAT GGCTTCAGGG AAGGCTTCTA TTTGTTTCCT 
GATGGACGAA ATCAGAATCC TGATCTGACT GGCTTATGTG AACCAACTCC CCAAGACCAT 
ATCAAAGTGA CCCAGGAACA ATATGAATTA TACTGTGAGA TGGGCTCCAC ATTCCAACTA 
TGTAAAATAT GTGCTGAAAA TGATAAGGAT GTAAAGATTG AGCCCTGTGG ACACCTCATG 
TGCACATCCT GTCTTACATC CTGGCAGGAA TCAGAAGGTC AGGGCTGTCC TTTCTGCCGA 
TGTGAAATTA AAGGTACTGA ACCCATCGTG GTAGATCCGT TTGATCCTAG AGGGAGTGGC 
AGCCTGTTGA GGCAAGGAGC AGAGGGAGCT CCCTCCCCAA ATTATGATGA TGATGATGAT 
GAACGAGCTG ATGATACTCT CTTCATGATG AAGGAATTGG CTGGTGCCAA GATGAAGAAA 
CTGAGGCACA AAGAGGTTAA GGAATTTGCC GAAGACCACA CAGCTAGTAG GTTGAAGCAT 
CTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011541359.1
CDS	143..1648
Translation	MAGNVKKSSGAGGGSGSGGSGSGGLIGLMKDAFQPHHHHHHHLSPHPPGTVDKKMVEKCWKLMDKVVRLCQNPKLALKNSPPYILDLLPDTYQHLRTILSRYEGKMETLGENEYFRVFMENLMKKTKQTISLFKEGKERMYEENSQPRRNLTKLSLIFSHMLAELKGIFPSGLFQGDTFRITKADAAEFWRKAFGEKTIVPWKSFRQALHEVHPISSGLEAMALKSTIDLTCNDYISVFEFDIFTRLFQPWSSLLRNWNSLAVTHPGYMAFLTYDEVKARLQKFIHKPGSYIFRLSCTRLGQWAIGYVTADGNILQTIPHNKPLFQALIDGFREGFYLFPDGRNQNPDLTGLCEPTPQDHIKVTQEQYELYCEMGSTFQLCKICAENDKDVKIEPCGHLMCTSCLTSWQESEGQGCPFCRCEIKGTEPIVVDPFDPRGSGSLLRQGAEGAPSPNYDDDDDERADDTLFMMKELAGAKMKKLRHKEVKEFAEDHTASRLKHL

Target ORF information:

RefSeq Version	XM_011543057.2
Organism	Homo sapiens(human)
Definition	Homo sapiens Cbl proto-oncogene (CBL), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011543057.2

ORF Insert Sequence:

ATGGCCGGCA ACGTGAAGAA GAGCTCTGGG GCCGGGGGCG GCAGCGGCTC CGGGGGCTCG 
GGTTCGGGTG GCCTGATTGG GCTCATGAAG GACGCCTTCC AGCCGCACCA CCACCACCAC 
CACCACCTCA GCCCCCACCC GCCGGGGACG GTGGACAAGA AGATGGTGGA GAAGTGCTGG 
AAGCTCATGG ACAAGGTGGT GCGGTTGTGT CAGAACCCAA AGCTGGCGCT AAAGAATAGC 
CCACCTTATA TCTTAGACCT GCTACCAGAT ACCTACCAGC ATCTCCGTAC TATCTTGTCA 
AGATATGAGG GGAAGATGGA GACACTTGGA GAAAATGAGT ATTTTAGGGT GTTTATGGAG 
AATTTGATGA AGAAAACTAA GCAAACCATA AGCCTCTTCA AGGAGGGAAA AGAAAGAATG 
TATGAGGAGA ATTCTCAGCC TAGGCGAAAC CTAACCAAAC TGTCCCTCAT CTTCAGCCAC 
ATGCTGGCAG AACTAAAAGG AATCTTTCCA AGTGGACTCT TTCAGGGAGA CACATTTCGG 
ATTACTAAAG CAGATGCTGC GGAATTTTGG AGAAAAGCTT TTGGGGAAAA GACAATAGTC 
CCTTGGAAGA GCTTTCGACA GGCTCTACAT GAAGTGCATC CCATCAGTTC TGGGCTGGAG 
GCCATGGCTC TGAAATCCAC TATTGATCTG ACCTGCAATG ATTATATTTC GGTTTTTGAA 
TTTGACATCT TTACCCGACT CTTTCAGCCC TGGTCCTCTT TGCTCAGGAA TTGGAACAGC 
CTTGCTGTAA CTCATCCTGG CTACATGGCT TTTTTGACGT ATGACGAAGT GAAAGCTCGG 
CTCCAGAAAT TCATTCACAA ACCTGGCAGT TATATCTTCC GGCTGAGCTG TACTCGTCTG 
GGTCAGTGGG CTATTGGGTA TGTTACTGCT GATGGGAACA TTCTCCAGAC AATCCCTCAC 
AATAAACCTC TCTTCCAAGC ACTGATTGAT GGCTTCAGGG AAGGCTTCTA TTTGTTTCCT 
GATGGACGAA ATCAGAATCC TGATCTGACT GGCTTATGTG AACCAACTCC CCAAGACCAT 
ATCAAAGTGA CCCAGGAACA ATATGAATTA TACTGTGAGA TGGGCTCCAC ATTCCAACTA 
TGTAAAATAT GTGCTGAAAA TGATAAGGAT GTAAAGATTG AGCCCTGTGG ACACCTCATG 
TGCACATCCT GTCTTACATC CTGGCAGGAA TCAGAAGGTC AGGGCTGTCC TTTCTGCCGA 
TGTGAAATTA AAGGTACTGA ACCCATCGTG GTAGATCCGT TTGATCCTAG AGGGAGTGGC 
AGCCTGTTGA GGCAAGGAGC AGAGGGAGCT CCCTCCCCAA ATTATGATGA TGATGATGAT 
GAACGAGCTG ATGATACTCT CTTCATGATG AAGGAATTGG CTGGTGCCAA GATGAAGAAA 
CTGAGGCACA AAGAGGTTAA GGAATTTGCC GAAGACCACA CAGCTAGTAG GTTGAAGCAT 
CTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CBL ( XM_017018511.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016874000.1 Homo sapiens Cbl proto-oncogene (CBL), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu92650
Clone ID Related Accession (Same CDS sequence)	XM_017018511.1
Accession Version	XM_017018511.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2241bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	E3 ubiquitin-protein ligase CBL isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000011.10) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCTGGCAG AACTAAAAGG AATCTTTCCA AGTGGACTCT TTCAGGGAGA CACATTTCGG 
ATTACTAAAG CAGATGCTGC GGAATTTTGG AGAAAAGCTT TTGGGGAAAA GACAATAGTC 
CCTTGGAAGA GCTTTCGACA GGCTCTACAT GAAGTGCATC CCATCAGTTC TGGGCTGGAG 
GCCATGGCTC TGAAATCCAC TATTGATCTG ACCTGCAATG ATTATATTTC GGTTTTTGAA 
TTTGACATCT TTACCCGACT CTTTCAGCCC TGGTCCTCTT TGCTCAGGAA TTGGAACAGC 
CTTGCTGTAA CTCATCCTGG CTACATGGCT TTTTTGACGT ATGACGAAGT GAAAGCTCGG 
CTCCAGAAAT TCATTCACAA ACCTGGCAGT TATATCTTCC GGCTGAGCTG TACTCGTCTG 
GGTCAGTGGG CTATTGGGTA TGTTACTGCT GATGGGAACA TTCTCCAGAC AATCCCTCAC 
AATAAACCTC TCTTCCAAGC ACTGATTGAT GGCTTCAGGG AAGGCTTCTA TTTGTTTCCT 
GATGGACGAA ATCAGAATCC TGATCTGACT GGCTTATGTG AACCAACTCC CCAAGACCAT 
ATCAAAGTGA CCCAGGAACA ATATGAATTA TACTGTGAGA TGGGCTCCAC ATTCCAACTA 
TGTAAAATAT GTGCTGAAAA TGATAAGGAT GTAAAGATTG AGCCCTGTGG ACACCTCATG 
TGCACATCCT GTCTTACATC CTGGCAGGAA TCAGAAGGTC AGGGCTGTCC TTTCTGCCGA 
TGTGAAATTA AAGGTACTGA ACCCATCGTG GTAGATCCGT TTGATCCTAG AGGGAGTGGC 
AGCCTGTTGA GGCAAGGAGC AGAGGGAGCT CCCTCCCCAA ATTATGATGA TGATGATGAT 
GAACGAGCTG ATGATACTCT CTTCATGATG AAGGAATTGG CTGGTGCCAA GGTGGAACGG 
CCGCCTTCTC CATTCTCCAT GGCCCCACAA GCTTCCCTTC CCCCGGTGCC ACCACGACTT 
GACCTTCTGC CGCAGCGAGT ATGTGTTCCC TCAAGTGCTT CTGCTCTTGG AACTGCTTCT 
AAGGCTGCTT CTGGCTCCCT TCATAAAGAC AAACCATTGC CAGTACCTCC CACACTTCGA 
GATCTTCCAC CACCACCGCC TCCAGACCGG CCATATTCTG TTGGAGCAGA ATCCCGACCT 
CAAAGACGCC CCTTGCCTTG TACACCAGGC GACTGTCCCT CCAGAGACAA ACTGCCCCCT 
GTCCCCTCTA GCCGCCTTGG AGACTCATGG CTGCCCCGGC CAATCCCCAA AGTACCAGTA 
TCTGCCCCAA GTTCCAGTGA TCCCTGGACA GGAAGAGAAT TAACCAACCG GCACTCACTT 
CCATTTTCAT TGCCCTCACA AATGGAGCCC AGACCAGATG TGCCTAGGCT CGGAAGCACG 
TTCAGTCTGG ATACCTCCAT GAGTATGAAT AGCAGCCCAT TAGTAGGTCC AGAGTGTGAC 
CACCCCAAAA TCAAACCTTC CTCATCTGCC AATGCCATTT ATTCTCTGGC TGCCAGACCT 
CTTCCTGTGC CAAAACTGCC ACCTGGGGAG CAATGTGAGG GTGAAGAGGA CACAGAGTAC 
ATGACTCCCT CTTCCAGGCC TCTACGGCCT TTGGATACAT CCCAGAGTTC ACGAGCATGT 
GATTGCGACC AGCAGATTGA TAGCTGTACG TATGAAGCAA TGTATAATAT TCAGTCCCAG 
GCGCCATCTA TCACCGAGAG CAGCACCTTT GGTGAAGGGA ATTTGGCCGC AGCCCATGCC 
AACACTGGTC CCGAGGAGTC AGAAAATGAG GATGATGGGT ATGATGTCCC AAAGCCACCT 
GTGCCGGCCG TGCTGGCCCG CCGAACTCTC TCAGATATCT CTAATGCCAG CTCCTCCTTT 
GGCTGGTTGT CTCTGGATGG TGATCCTACA ACAAATGTCA CTGAAGGTTC CCAAGTTCCC 
GAGAGGCCTC CAAAACCATT CCCGCGGAGA ATCAACTCTG AACGGAAAGC TGGCAGCTGT 
CAGCAAGGTA GTGGTCCTGC CGCCTCTGCT GCCACCGCCT CACCTCAGCT CTCCAGTGAG 
ATCGAGAACC TCATGAGTCA GGGGTACTCC TACCAGGACA TCCAGAAAGC TTTGGTCATT 
GCCCAGAACA ACATCGAGAT GGCCAAAAAC ATCCTCCGGG AATTTGTTTC CATTTCTTCT 
CCTGCCCATG TAGCTACCTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016874000.1
CDS	58..2298
Translation	MLAELKGIFPSGLFQGDTFRITKADAAEFWRKAFGEKTIVPWKSFRQALHEVHPISSGLEAMALKSTIDLTCNDYISVFEFDIFTRLFQPWSSLLRNWNSLAVTHPGYMAFLTYDEVKARLQKFIHKPGSYIFRLSCTRLGQWAIGYVTADGNILQTIPHNKPLFQALIDGFREGFYLFPDGRNQNPDLTGLCEPTPQDHIKVTQEQYELYCEMGSTFQLCKICAENDKDVKIEPCGHLMCTSCLTSWQESEGQGCPFCRCEIKGTEPIVVDPFDPRGSGSLLRQGAEGAPSPNYDDDDDERADDTLFMMKELAGAKVERPPSPFSMAPQASLPPVPPRLDLLPQRVCVPSSASALGTASKAASGSLHKDKPLPVPPTLRDLPPPPPPDRPYSVGAESRPQRRPLPCTPGDCPSRDKLPPVPSSRLGDSWLPRPIPKVPVSAPSSSDPWTGRELTNRHSLPFSLPSQMEPRPDVPRLGSTFSLDTSMSMNSSPLVGPECDHPKIKPSSSANAIYSLAARPLPVPKLPPGEQCEGEEDTEYMTPSSRPLRPLDTSQSSRACDCDQQIDSCTYEAMYNIQSQAPSITESSTFGEGNLAAAHANTGPEESENEDDGYDVPKPPVPAVLARRTLSDISNASSSFGWLSLDGDPTTNVTEGSQVPERPPKPFPRRINSERKAGSCQQGSGPAASAATASPQLSSEIENLMSQGYSYQDIQKALVIAQNNIEMAKNILREFVSISSPAHVAT

Target ORF information:

RefSeq Version	XM_017018511.1
Organism	Homo sapiens(human)
Definition	Homo sapiens Cbl proto-oncogene (CBL), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017018511.1

ORF Insert Sequence:

ATGCTGGCAG AACTAAAAGG AATCTTTCCA AGTGGACTCT TTCAGGGAGA CACATTTCGG 
ATTACTAAAG CAGATGCTGC GGAATTTTGG AGAAAAGCTT TTGGGGAAAA GACAATAGTC 
CCTTGGAAGA GCTTTCGACA GGCTCTACAT GAAGTGCATC CCATCAGTTC TGGGCTGGAG 
GCCATGGCTC TGAAATCCAC TATTGATCTG ACCTGCAATG ATTATATTTC GGTTTTTGAA 
TTTGACATCT TTACCCGACT CTTTCAGCCC TGGTCCTCTT TGCTCAGGAA TTGGAACAGC 
CTTGCTGTAA CTCATCCTGG CTACATGGCT TTTTTGACGT ATGACGAAGT GAAAGCTCGG 
CTCCAGAAAT TCATTCACAA ACCTGGCAGT TATATCTTCC GGCTGAGCTG TACTCGTCTG 
GGTCAGTGGG CTATTGGGTA TGTTACTGCT GATGGGAACA TTCTCCAGAC AATCCCTCAC 
AATAAACCTC TCTTCCAAGC ACTGATTGAT GGCTTCAGGG AAGGCTTCTA TTTGTTTCCT 
GATGGACGAA ATCAGAATCC TGATCTGACT GGCTTATGTG AACCAACTCC CCAAGACCAT 
ATCAAAGTGA CCCAGGAACA ATATGAATTA TACTGTGAGA TGGGCTCCAC ATTCCAACTA 
TGTAAAATAT GTGCTGAAAA TGATAAGGAT GTAAAGATTG AGCCCTGTGG ACACCTCATG 
TGCACATCCT GTCTTACATC CTGGCAGGAA TCAGAAGGTC AGGGCTGTCC TTTCTGCCGA 
TGTGAAATTA AAGGTACTGA ACCCATCGTG GTAGATCCGT TTGATCCTAG AGGGAGTGGC 
AGCCTGTTGA GGCAAGGAGC AGAGGGAGCT CCCTCCCCAA ATTATGATGA TGATGATGAT 
GAACGAGCTG ATGATACTCT CTTCATGATG AAGGAATTGG CTGGTGCCAA GGTGGAACGG 
CCGCCTTCTC CATTCTCCAT GGCCCCACAA GCTTCCCTTC CCCCGGTGCC ACCACGACTT 
GACCTTCTGC CGCAGCGAGT ATGTGTTCCC TCAAGTGCTT CTGCTCTTGG AACTGCTTCT 
AAGGCTGCTT CTGGCTCCCT TCATAAAGAC AAACCATTGC CAGTACCTCC CACACTTCGA 
GATCTTCCAC CACCACCGCC TCCAGACCGG CCATATTCTG TTGGAGCAGA ATCCCGACCT 
CAAAGACGCC CCTTGCCTTG TACACCAGGC GACTGTCCCT CCAGAGACAA ACTGCCCCCT 
GTCCCCTCTA GCCGCCTTGG AGACTCATGG CTGCCCCGGC CAATCCCCAA AGTACCAGTA 
TCTGCCCCAA GTTCCAGTGA TCCCTGGACA GGAAGAGAAT TAACCAACCG GCACTCACTT 
CCATTTTCAT TGCCCTCACA AATGGAGCCC AGACCAGATG TGCCTAGGCT CGGAAGCACG 
TTCAGTCTGG ATACCTCCAT GAGTATGAAT AGCAGCCCAT TAGTAGGTCC AGAGTGTGAC 
CACCCCAAAA TCAAACCTTC CTCATCTGCC AATGCCATTT ATTCTCTGGC TGCCAGACCT 
CTTCCTGTGC CAAAACTGCC ACCTGGGGAG CAATGTGAGG GTGAAGAGGA CACAGAGTAC 
ATGACTCCCT CTTCCAGGCC TCTACGGCCT TTGGATACAT CCCAGAGTTC ACGAGCATGT 
GATTGCGACC AGCAGATTGA TAGCTGTACG TATGAAGCAA TGTATAATAT TCAGTCCCAG 
GCGCCATCTA TCACCGAGAG CAGCACCTTT GGTGAAGGGA ATTTGGCCGC AGCCCATGCC 
AACACTGGTC CCGAGGAGTC AGAAAATGAG GATGATGGGT ATGATGTCCC AAAGCCACCT 
GTGCCGGCCG TGCTGGCCCG CCGAACTCTC TCAGATATCT CTAATGCCAG CTCCTCCTTT 
GGCTGGTTGT CTCTGGATGG TGATCCTACA ACAAATGTCA CTGAAGGTTC CCAAGTTCCC 
GAGAGGCCTC CAAAACCATT CCCGCGGAGA ATCAACTCTG AACGGAAAGC TGGCAGCTGT 
CAGCAAGGTA GTGGTCCTGC CGCCTCTGCT GCCACCGCCT CACCTCAGCT CTCCAGTGAG 
ATCGAGAACC TCATGAGTCA GGGGTACTCC TACCAGGACA TCCAGAAAGC TTTGGTCATT 
GCCCAGAACA ACATCGAGAT GGCCAAAAAC ATCCTCCGGG AATTTGTTTC CATTTCTTCT 
CCTGCCCATG TAGCTACCTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

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03-6811-6572

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03-6811-6573
050-3174-7589(受注専用)

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CBL cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

見積依頼

Eメール

電話

FAX

オンラインフォーム

サポート

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サポート

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