SLC25A12 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	SLC25A12
Entrez Gene ID	8604
Full Name	solute carrier family 25 member 12
Synonyms	AGC1,ARALAR,EIEE39
General protein information	Preferred Names solute carrier family 25 member 12 Names calcium-binding mitochondrial carrier protein Aralar1 araceli hiperlarga calcium binding mitochondrial carrier superfamily member Aralar1 mitochondrial aspartate glutamate carrier 1 solute carrier family 25 (aspartate/glutamate carrier), member 12 solute carrier family 25 (mitochondrial carrier, Aralar), member 12
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 2 Map Location: 2q31.1
Summary	This gene encodes a calcium-binding mitochondrial carrier protein. The encoded protein localizes to the mitochondria and is involved in the exchange of aspartate for glutamate across the inner mitochondrial membrane. Polymorphisms in this gene may be associated with autism, and mutations in this gene may also be a cause of global cerebral hypomyelination. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Apr 2012].
Disorder MIM:	603667
Disorder Html:	Epileptic encephalopathy, early infantile, 39, 612949 (3)

mRNA and Protein(s)

mRNA	Protein	Name
XM_011512070.2	XP_011510372.1	calcium-binding mitochondrial carrier protein Aralar1 isoform X1
NM_003705.4	NP_003696.2	calcium-binding mitochondrial carrier protein Aralar1
NM_003705.5	NP_003696.2	calcium-binding mitochondrial carrier protein Aralar1
XM_011512070.3	XP_011510372.1	calcium-binding mitochondrial carrier protein Aralar1 isoform X1

Pathways from BioSystems

Homologies

Caenorhabditis elegans (roundworm)	K02F3.2	NP_497274.2
	SLC25A12	XP_001085208.1
Canis lupus familiaris (dog)	SLC25A12	XP_005640369.1
Gallus gallus (chicken)	SLC25A12	XP_428938.4
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP000958	XP_309148.5
Neurospora crassa	NCU01241	XP_961607.1
Homo sapiens (human)	SLC25A12	NP_003696.2
Pan troglodytes (chimpanzee)	SLC25A12	XP_003949966.1
Bos taurus (cattle)	SLC25A12	NP_001094664.1
Mus musculus (house mouse)	Slc25a12	NP_766024.1
Danio rerio (zebrafish)	slc25a12	NP_997947.1
Drosophila melanogaster (fruit fly)	aralar1	NP_001247368.1
Magnaporthe oryzae (rice blast fungus)	MGG_07066	XP_003715248.1

Gene Ontology
Bibliography

Related articles in PubMed

Single Nucleotide Polymorphisms in SLC19A1 and SLC25A9 Are Associated with Childhood Autism Spectrum Disorder in the Chinese Han Population.
Liu J, Mo W, Zhang Z, Yu H, Yang A, Qu F, Hu P, Liu Z, Wang S
Journal of molecular neuroscience : MN62(2)262-267(2017 Jun)

AGC1/2, the mitochondrial aspartate-glutamate carriers.
Amoedo ND, Punzi G, Obre E, Lacombe D, De Grassi A, Pierri CL, Rossignol R
Biochimica et biophysica acta1863(10)2394-412(2016 10)

Mitochondrial Aspartate/Glutamate Carrier SLC25A12 and Autism Spectrum Disorder: a Meta-Analysis.
Aoki Y, Cortese S
Molecular neurobiology53(3)1579-1588(2016 Apr)

Association between genetic variants in SLC25A12 and risk of autism spectrum disorders: An integrated meta-analysis.
Liu J, Yang A, Zhang Q, Yang G, Yang W, Lei H, Quan J, Qu F, Wang M, Zhang Z, Yu K
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics168B(4)236-46(2015 Jun)

Calcium-induced conformational changes of the regulatory domain of human mitochondrial aspartate/glutamate carriers.
Thangaratnarajah C, Ruprecht JJ, Kunji ER
Nature communications55491(2014 Nov)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The features of AGC1 structure and function in physiology and pathology, regulation by calcium, dependency on mitochondrial membrane potential, role in cancer cells, and tissue specificity are reviewed. AGC1 is involved in the glutamate-mediated excitotoxicity in neurons and AGC gene or protein alterations were discovered in rare human diseases. Review.
Title: AGC1/2, the mitochondrial aspartate-glutamate carriers.

Sensitivity analyses including only studies with family-based design demonstrated significant association between autism spectrum disorders and SNPs rs2292813 and rs2056202. In contrast, sensitivity analyses including case-control design studies only failed to find a significant association. Review.
Title: Mitochondrial Aspartate/Glutamate Carrier SLC25A12 and Autism Spectrum Disorder: a Meta-Analysis.

rs2056202 and rs2292813 in SLC25A12 may contribute significantly to autism spectrum disorders risk.
Title: Association between genetic variants in SLC25A12 and risk of autism spectrum disorders: An integrated meta-analysis.

Structure of the calcium bound and calcium free N- and C-terminal domains is described, elucidating the mechanism of calcium regulation.
Title: Calcium-induced conformational changes of the regulatory domain of human mitochondrial aspartate/glutamate carriers.

Compares and contrasts all the known human SLC25A* genes and includes functional information.
Title: The mitochondrial transporter family SLC25: identification, properties and physiopathology.

The following SLC25A12 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the SLC25A12 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu20364	NM_003705.5 Latest version!	Homo sapiens solute carrier family 25 member 12 (SLC25A12), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$344.50-$482.30 $689.00
OHu62019	XM_011512070.3 Latest version!	Homo sapiens solute carrier family 25 member 12 (SLC25A12), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
View Old Accession Versions >>
OHu20364	NM_003705.4	Homo sapiens solute carrier family 25 member 12 (SLC25A12), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$344.50-$482.30 $689.00
OHu62019	XM_011512070.2	Homo sapiens solute carrier family 25 member 12 (SLC25A12), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
Hide Old Accession Versions >>

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***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

SLC25A12 ( NM_003705.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_003696.2 Homo sapiens solute carrier family 25 member 12 (SLC25A12), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu20364
Clone ID Related Accession (Same CDS sequence)	NM_003705.4 , NM_003705.5
Accession Version	NM_003705.4	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2037bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-11-28
Organism	Homo sapiens(human)
Product	calcium-binding mitochondrial carrier protein Aralar1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC068039.6 and AJ496568.1. This sequence is a reference standard in the RefSeqGene project. On Apr 10, 2012 this sequence version replaced NM_003705.3. Transcript Variant: This variant (1) represents the longer transcript and is protein-coding. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660803.28634.1, SRR1803614.98292.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: reported by MitoCarta ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGCGGTCA AGGTGCAGAC AACTAAGCGA GGGGATCCTC ATGAGTTAAG AAACATATTT 
CTACAGTATG CCAGTACTGA GGTTGATGGA GAGCGTTATA TGACCCCAGA AGACTTTGTT 
CAGCGCTATC TTGGACTGTA TAATGATCCA AATAGTAACC CAAAGATCGT GCAGCTCTTG 
GCAGGAGTAG CTGATCAAAC CAAGGATGGG TTGATCTCCT ATCAAGAGTT TTTGGCATTT 
GAATCTGTTT TATGTGCTCC AGATTCCATG TTCATAGTGG CTTTCCAGTT GTTTGACAAG 
AGTGGAAATG GAGAGGTGAC ATTTGAAAAT GTCAAAGAAA TTTTTGGACA GACTATTATT 
CATCATCATA TCCCTTTTAA CTGGGATTGT GAATTTATCC GACTGCATTT TGGGCATAAC 
CGGAAGAAGC ATCTTAACTA CACAGAATTC ACGCAGTTTC TCCAGGAGCT GCAATTGGAA 
CATGCAAGAC AAGCCTTTGC ACTCAAAGAC AAAAGCAAAA GTGGCATGAT TTCTGGTCTG 
GATTTCAGTG ACATCATGGT TACCATTAGA TCTCACATGC TTACTCCTTT TGTGGAGGAG 
AACTTAGTTT CAGCAGCTGG AGGAAGTATC TCACACCAGG TTAGCTTCTC CTACTTCAAT 
GCATTTAACT CGTTACTGAA TAACATGGAG CTTGTTCGTA AGATATATAG CACTCTAGCT 
GGCACAAGGA AAGATGTTGA AGTCACAAAG GAGGAATTTG CCCAGAGTGC CATACGCTAT 
GGACAAGTCA CACCACTAGA AATTGATATT CTATATCAGC TTGCAGACTT ATATAATGCT 
TCAGGGCGCT TGACTTTGGC AGATATTGAG AGAATAGCCC CATTGGCTGA GGGGGCCTTA 
CCTTACAACC TGGCAGAACT TCAGAGACAG CAGTCTCCTG GGTTAGGCAG GCCTATCTGG 
CTCCAGATTG CCGAGTCTGC TTACAGATTC ACTCTGGGCT CAGTTGCTGG AGCTGTGGGA 
GCCACTGCAG TGTATCCTAT AGATCTGGTG AAGACCCGAA TGCAAAACCA GCGTGGCTCT 
GGCTCTGTTG TTGGGGAGCT AATGTACAAA AACAGCTTTG ACTGTTTTAA GAAAGTCTTG 
CGTTATGAGG GCTTCTTTGG ACTCTACAGG GGTCTGATAC CACAACTTAT AGGGGTTGCT 
CCAGAAAAGG CCATTAAACT GACTGTTAAT GATTTTGTTC GGGACAAATT TACCAGAAGA 
GATGGCTCTG TTCCACTTCC AGCAGAAGTT CTTGCTGGAG GCTGTGCTGG AGGCTCTCAG 
GTCATTTTTA CCAACCCATT GGAGATAGTG AAGATTCGTC TGCAAGTAGC TGGAGAGATC 
ACCACGGGAC CCAGAGTCAG CGCCCTGAAT GTGCTCCGGG ACTTGGGAAT TTTTGGTCTG 
TATAAGGGTG CCAAAGCGTG TTTCCTCCGA GACATTCCCT TCTCTGCAAT CTATTTTCCT 
GTTTATGCTC ATTGCAAACT ACTTCTGGCT GATGAAAATG GACACGTGGG AGGTTTAAAT 
CTTCTTGCAG CTGGAGCCAT GGCAGGTGTC CCAGCTGCAT CTCTGGTGAC CCCTGCTGAT 
GTCATCAAGA CAAGACTGCA GGTGGCTGCC CGCGCTGGCC AGACGACATA CAGTGGTGTC 
ATCGACTGTT TCAGGAAGAT TCTCCGGGAA GAAGGGCCCT CAGCATTTTG GAAAGGGACT 
GCAGCTCGAG TGTTTCGATC CTCTCCCCAG TTTGGTGTTA CCTTGGTCAC TTATGAACTT 
CTCCAGCGGT GGTTTTACAT TGATTTTGGA GGCCTCAAAC CCGCTGGTTC AGAACCAACA 
CCTAAGTCAC GCATTGCAGA CCTTCCTCCT GCCAACCCTG ATCACATCGG TGGATACAGA 
CTCGCCACAG CCACGTTTGC AGGCATCGAA AACAAATTTG GCCTTTATCT CCCGAAATTT 
AAGTCTCCTA GTGTTGCTGT GGTTCAGCCA AAGGCAGCAG TGGCAGCCAC TCAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_003696.2
CDS	93..2129
Translation	MAVKVQTTKRGDPHELRNIFLQYASTEVDGERYMTPEDFVQRYLGLYNDPNSNPKIVQLLAGVADQTKDGLISYQEFLAFESVLCAPDSMFIVAFQLFDKSGNGEVTFENVKEIFGQTIIHHHIPFNWDCEFIRLHFGHNRKKHLNYTEFTQFLQELQLEHARQAFALKDKSKSGMISGLDFSDIMVTIRSHMLTPFVEENLVSAAGGSISHQVSFSYFNAFNSLLNNMELVRKIYSTLAGTRKDVEVTKEEFAQSAIRYGQVTPLEIDILYQLADLYNASGRLTLADIERIAPLAEGALPYNLAELQRQQSPGLGRPIWLQIAESAYRFTLGSVAGAVGATAVYPIDLVKTRMQNQRGSGSVVGELMYKNSFDCFKKVLRYEGFFGLYRGLIPQLIGVAPEKAIKLTVNDFVRDKFTRRDGSVPLPAEVLAGGCAGGSQVIFTNPLEIVKIRLQVAGEITTGPRVSALNVLRDLGIFGLYKGAKACFLRDIPFSAIYFPVYAHCKLLLADENGHVGGLNLLAAGAMAGVPAASLVTPADVIKTRLQVAARAGQTTYSGVIDCFRKILREEGPSAFWKGTAARVFRSSPQFGVTLVTYELLQRWFYIDFGGLKPAGSEPTPKSRIADLPPANPDHIGGYRLATATFAGIENKFGLYLPKFKSPSVAVVQPKAAVAATQ

Target ORF information:

RefSeq Version	NM_003705.4
Organism	Homo sapiens(human)
Definition	Homo sapiens solute carrier family 25 member 12 (SLC25A12), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_003705.4

ORF Insert Sequence:

ATGGCGGTCA AGGTGCAGAC AACTAAGCGA GGGGATCCTC ATGAGTTAAG AAACATATTT 
CTACAGTATG CCAGTACTGA GGTTGATGGA GAGCGTTATA TGACCCCAGA AGACTTTGTT 
CAGCGCTATC TTGGACTGTA TAATGATCCA AATAGTAACC CAAAGATCGT GCAGCTCTTG 
GCAGGAGTAG CTGATCAAAC CAAGGATGGG TTGATCTCCT ATCAAGAGTT TTTGGCATTT 
GAATCTGTTT TATGTGCTCC AGATTCCATG TTCATAGTGG CTTTCCAGTT GTTTGACAAG 
AGTGGAAATG GAGAGGTGAC ATTTGAAAAT GTCAAAGAAA TTTTTGGACA GACTATTATT 
CATCATCATA TCCCTTTTAA CTGGGATTGT GAATTTATCC GACTGCATTT TGGGCATAAC 
CGGAAGAAGC ATCTTAACTA CACAGAATTC ACGCAGTTTC TCCAGGAGCT GCAATTGGAA 
CATGCAAGAC AAGCCTTTGC ACTCAAAGAC AAAAGCAAAA GTGGCATGAT TTCTGGTCTG 
GATTTCAGTG ACATCATGGT TACCATTAGA TCTCACATGC TTACTCCTTT TGTGGAGGAG 
AACTTAGTTT CAGCAGCTGG AGGAAGTATC TCACACCAGG TTAGCTTCTC CTACTTCAAT 
GCATTTAACT CGTTACTGAA TAACATGGAG CTTGTTCGTA AGATATATAG CACTCTAGCT 
GGCACAAGGA AAGATGTTGA AGTCACAAAG GAGGAATTTG CCCAGAGTGC CATACGCTAT 
GGACAAGTCA CACCACTAGA AATTGATATT CTATATCAGC TTGCAGACTT ATATAATGCT 
TCAGGGCGCT TGACTTTGGC AGATATTGAG AGAATAGCCC CATTGGCTGA GGGGGCCTTA 
CCTTACAACC TGGCAGAACT TCAGAGACAG CAGTCTCCTG GGTTAGGCAG GCCTATCTGG 
CTCCAGATTG CCGAGTCTGC TTACAGATTC ACTCTGGGCT CAGTTGCTGG AGCTGTGGGA 
GCCACTGCAG TGTATCCTAT AGATCTGGTG AAGACCCGAA TGCAAAACCA GCGTGGCTCT 
GGCTCTGTTG TTGGGGAGCT AATGTACAAA AACAGCTTTG ACTGTTTTAA GAAAGTCTTG 
CGTTATGAGG GCTTCTTTGG ACTCTACAGG GGTCTGATAC CACAACTTAT AGGGGTTGCT 
CCAGAAAAGG CCATTAAACT GACTGTTAAT GATTTTGTTC GGGACAAATT TACCAGAAGA 
GATGGCTCTG TTCCACTTCC AGCAGAAGTT CTTGCTGGAG GCTGTGCTGG AGGCTCTCAG 
GTCATTTTTA CCAACCCATT GGAGATAGTG AAGATTCGTC TGCAAGTAGC TGGAGAGATC 
ACCACGGGAC CCAGAGTCAG CGCCCTGAAT GTGCTCCGGG ACTTGGGAAT TTTTGGTCTG 
TATAAGGGTG CCAAAGCGTG TTTCCTCCGA GACATTCCCT TCTCTGCAAT CTATTTTCCT 
GTTTATGCTC ATTGCAAACT ACTTCTGGCT GATGAAAATG GACACGTGGG AGGTTTAAAT 
CTTCTTGCAG CTGGAGCCAT GGCAGGTGTC CCAGCTGCAT CTCTGGTGAC CCCTGCTGAT 
GTCATCAAGA CAAGACTGCA GGTGGCTGCC CGCGCTGGCC AGACGACATA CAGTGGTGTC 
ATCGACTGTT TCAGGAAGAT TCTCCGGGAA GAAGGGCCCT CAGCATTTTG GAAAGGGACT 
GCAGCTCGAG TGTTTCGATC CTCTCCCCAG TTTGGTGTTA CCTTGGTCAC TTATGAACTT 
CTCCAGCGGT GGTTTTACAT TGATTTTGGA GGCCTCAAAC CCGCTGGTTC AGAACCAACA 
CCTAAGTCAC GCATTGCAGA CCTTCCTCCT GCCAACCCTG ATCACATCGG TGGATACAGA 
CTCGCCACAG CCACGTTTGC AGGCATCGAA AACAAATTTG GCCTTTATCT CCCGAAATTT 
AAGTCTCCTA GTGTTGCTGT GGTTCAGCCA AAGGCAGCAG TGGCAGCCAC TCAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SLC25A12 ( NM_003705.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_003696.2 Homo sapiens solute carrier family 25 member 12 (SLC25A12), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu20364
Clone ID Related Accession (Same CDS sequence)	NM_003705.4 , NM_003705.5
Accession Version	NM_003705.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2037bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-30
Organism	Homo sapiens(human)
Product	calcium-binding mitochondrial carrier protein Aralar1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC068039.6 and AJ496568.1. This sequence is a reference standard in the RefSeqGene project. On Nov 22, 2018 this sequence version replaced NM_003705.4. Transcript Variant: This variant (1) represents the longer transcript and is protein-coding. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803615.95919.1, SRR1660803.28634.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: reported by MitoCarta MANE Ensembl match :: ENST00000422440.7/ ENSP00000388658.2 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGCGGTCA AGGTGCAGAC AACTAAGCGA GGGGATCCTC ATGAGTTAAG AAACATATTT 
CTACAGTATG CCAGTACTGA GGTTGATGGA GAGCGTTATA TGACCCCAGA AGACTTTGTT 
CAGCGCTATC TTGGACTGTA TAATGATCCA AATAGTAACC CAAAGATCGT GCAGCTCTTG 
GCAGGAGTAG CTGATCAAAC CAAGGATGGG TTGATCTCCT ATCAAGAGTT TTTGGCATTT 
GAATCTGTTT TATGTGCTCC AGATTCCATG TTCATAGTGG CTTTCCAGTT GTTTGACAAG 
AGTGGAAATG GAGAGGTGAC ATTTGAAAAT GTCAAAGAAA TTTTTGGACA GACTATTATT 
CATCATCATA TCCCTTTTAA CTGGGATTGT GAATTTATCC GACTGCATTT TGGGCATAAC 
CGGAAGAAGC ATCTTAACTA CACAGAATTC ACGCAGTTTC TCCAGGAGCT GCAATTGGAA 
CATGCAAGAC AAGCCTTTGC ACTCAAAGAC AAAAGCAAAA GTGGCATGAT TTCTGGTCTG 
GATTTCAGTG ACATCATGGT TACCATTAGA TCTCACATGC TTACTCCTTT TGTGGAGGAG 
AACTTAGTTT CAGCAGCTGG AGGAAGTATC TCACACCAGG TTAGCTTCTC CTACTTCAAT 
GCATTTAACT CGTTACTGAA TAACATGGAG CTTGTTCGTA AGATATATAG CACTCTAGCT 
GGCACAAGGA AAGATGTTGA AGTCACAAAG GAGGAATTTG CCCAGAGTGC CATACGCTAT 
GGACAAGTCA CACCACTAGA AATTGATATT CTATATCAGC TTGCAGACTT ATATAATGCT 
TCAGGGCGCT TGACTTTGGC AGATATTGAG AGAATAGCCC CATTGGCTGA GGGGGCCTTA 
CCTTACAACC TGGCAGAACT TCAGAGACAG CAGTCTCCTG GGTTAGGCAG GCCTATCTGG 
CTCCAGATTG CCGAGTCTGC TTACAGATTC ACTCTGGGCT CAGTTGCTGG AGCTGTGGGA 
GCCACTGCAG TGTATCCTAT AGATCTGGTG AAGACCCGAA TGCAAAACCA GCGTGGCTCT 
GGCTCTGTTG TTGGGGAGCT AATGTACAAA AACAGCTTTG ACTGTTTTAA GAAAGTCTTG 
CGTTATGAGG GCTTCTTTGG ACTCTACAGG GGTCTGATAC CACAACTTAT AGGGGTTGCT 
CCAGAAAAGG CCATTAAACT GACTGTTAAT GATTTTGTTC GGGACAAATT TACCAGAAGA 
GATGGCTCTG TTCCACTTCC AGCAGAAGTT CTTGCTGGAG GCTGTGCTGG AGGCTCTCAG 
GTCATTTTTA CCAACCCATT GGAGATAGTG AAGATTCGTC TGCAAGTAGC TGGAGAGATC 
ACCACGGGAC CCAGAGTCAG CGCCCTGAAT GTGCTCCGGG ACTTGGGAAT TTTTGGTCTG 
TATAAGGGTG CCAAAGCGTG TTTCCTCCGA GACATTCCCT TCTCTGCAAT CTATTTTCCT 
GTTTATGCTC ATTGCAAACT ACTTCTGGCT GATGAAAATG GACACGTGGG AGGTTTAAAT 
CTTCTTGCAG CTGGAGCCAT GGCAGGTGTC CCAGCTGCAT CTCTGGTGAC CCCTGCTGAT 
GTCATCAAGA CAAGACTGCA GGTGGCTGCC CGCGCTGGCC AGACGACATA CAGTGGTGTC 
ATCGACTGTT TCAGGAAGAT TCTCCGGGAA GAAGGGCCCT CAGCATTTTG GAAAGGGACT 
GCAGCTCGAG TGTTTCGATC CTCTCCCCAG TTTGGTGTTA CCTTGGTCAC TTATGAACTT 
CTCCAGCGGT GGTTTTACAT TGATTTTGGA GGCCTCAAAC CCGCTGGTTC AGAACCAACA 
CCTAAGTCAC GCATTGCAGA CCTTCCTCCT GCCAACCCTG ATCACATCGG TGGATACAGA 
CTCGCCACAG CCACGTTTGC AGGCATCGAA AACAAATTTG GCCTTTATCT CCCGAAATTT 
AAGTCTCCTA GTGTTGCTGT GGTTCAGCCA AAGGCAGCAG TGGCAGCCAC TCAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_003696.2
CDS	31..2067
Translation	MAVKVQTTKRGDPHELRNIFLQYASTEVDGERYMTPEDFVQRYLGLYNDPNSNPKIVQLLAGVADQTKDGLISYQEFLAFESVLCAPDSMFIVAFQLFDKSGNGEVTFENVKEIFGQTIIHHHIPFNWDCEFIRLHFGHNRKKHLNYTEFTQFLQELQLEHARQAFALKDKSKSGMISGLDFSDIMVTIRSHMLTPFVEENLVSAAGGSISHQVSFSYFNAFNSLLNNMELVRKIYSTLAGTRKDVEVTKEEFAQSAIRYGQVTPLEIDILYQLADLYNASGRLTLADIERIAPLAEGALPYNLAELQRQQSPGLGRPIWLQIAESAYRFTLGSVAGAVGATAVYPIDLVKTRMQNQRGSGSVVGELMYKNSFDCFKKVLRYEGFFGLYRGLIPQLIGVAPEKAIKLTVNDFVRDKFTRRDGSVPLPAEVLAGGCAGGSQVIFTNPLEIVKIRLQVAGEITTGPRVSALNVLRDLGIFGLYKGAKACFLRDIPFSAIYFPVYAHCKLLLADENGHVGGLNLLAAGAMAGVPAASLVTPADVIKTRLQVAARAGQTTYSGVIDCFRKILREEGPSAFWKGTAARVFRSSPQFGVTLVTYELLQRWFYIDFGGLKPAGSEPTPKSRIADLPPANPDHIGGYRLATATFAGIENKFGLYLPKFKSPSVAVVQPKAAVAATQ

Target ORF information:

RefSeq Version	NM_003705.5
Organism	Homo sapiens(human)
Definition	Homo sapiens solute carrier family 25 member 12 (SLC25A12), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_003705.5

ORF Insert Sequence:

ATGGCGGTCA AGGTGCAGAC AACTAAGCGA GGGGATCCTC ATGAGTTAAG AAACATATTT 
CTACAGTATG CCAGTACTGA GGTTGATGGA GAGCGTTATA TGACCCCAGA AGACTTTGTT 
CAGCGCTATC TTGGACTGTA TAATGATCCA AATAGTAACC CAAAGATCGT GCAGCTCTTG 
GCAGGAGTAG CTGATCAAAC CAAGGATGGG TTGATCTCCT ATCAAGAGTT TTTGGCATTT 
GAATCTGTTT TATGTGCTCC AGATTCCATG TTCATAGTGG CTTTCCAGTT GTTTGACAAG 
AGTGGAAATG GAGAGGTGAC ATTTGAAAAT GTCAAAGAAA TTTTTGGACA GACTATTATT 
CATCATCATA TCCCTTTTAA CTGGGATTGT GAATTTATCC GACTGCATTT TGGGCATAAC 
CGGAAGAAGC ATCTTAACTA CACAGAATTC ACGCAGTTTC TCCAGGAGCT GCAATTGGAA 
CATGCAAGAC AAGCCTTTGC ACTCAAAGAC AAAAGCAAAA GTGGCATGAT TTCTGGTCTG 
GATTTCAGTG ACATCATGGT TACCATTAGA TCTCACATGC TTACTCCTTT TGTGGAGGAG 
AACTTAGTTT CAGCAGCTGG AGGAAGTATC TCACACCAGG TTAGCTTCTC CTACTTCAAT 
GCATTTAACT CGTTACTGAA TAACATGGAG CTTGTTCGTA AGATATATAG CACTCTAGCT 
GGCACAAGGA AAGATGTTGA AGTCACAAAG GAGGAATTTG CCCAGAGTGC CATACGCTAT 
GGACAAGTCA CACCACTAGA AATTGATATT CTATATCAGC TTGCAGACTT ATATAATGCT 
TCAGGGCGCT TGACTTTGGC AGATATTGAG AGAATAGCCC CATTGGCTGA GGGGGCCTTA 
CCTTACAACC TGGCAGAACT TCAGAGACAG CAGTCTCCTG GGTTAGGCAG GCCTATCTGG 
CTCCAGATTG CCGAGTCTGC TTACAGATTC ACTCTGGGCT CAGTTGCTGG AGCTGTGGGA 
GCCACTGCAG TGTATCCTAT AGATCTGGTG AAGACCCGAA TGCAAAACCA GCGTGGCTCT 
GGCTCTGTTG TTGGGGAGCT AATGTACAAA AACAGCTTTG ACTGTTTTAA GAAAGTCTTG 
CGTTATGAGG GCTTCTTTGG ACTCTACAGG GGTCTGATAC CACAACTTAT AGGGGTTGCT 
CCAGAAAAGG CCATTAAACT GACTGTTAAT GATTTTGTTC GGGACAAATT TACCAGAAGA 
GATGGCTCTG TTCCACTTCC AGCAGAAGTT CTTGCTGGAG GCTGTGCTGG AGGCTCTCAG 
GTCATTTTTA CCAACCCATT GGAGATAGTG AAGATTCGTC TGCAAGTAGC TGGAGAGATC 
ACCACGGGAC CCAGAGTCAG CGCCCTGAAT GTGCTCCGGG ACTTGGGAAT TTTTGGTCTG 
TATAAGGGTG CCAAAGCGTG TTTCCTCCGA GACATTCCCT TCTCTGCAAT CTATTTTCCT 
GTTTATGCTC ATTGCAAACT ACTTCTGGCT GATGAAAATG GACACGTGGG AGGTTTAAAT 
CTTCTTGCAG CTGGAGCCAT GGCAGGTGTC CCAGCTGCAT CTCTGGTGAC CCCTGCTGAT 
GTCATCAAGA CAAGACTGCA GGTGGCTGCC CGCGCTGGCC AGACGACATA CAGTGGTGTC 
ATCGACTGTT TCAGGAAGAT TCTCCGGGAA GAAGGGCCCT CAGCATTTTG GAAAGGGACT 
GCAGCTCGAG TGTTTCGATC CTCTCCCCAG TTTGGTGTTA CCTTGGTCAC TTATGAACTT 
CTCCAGCGGT GGTTTTACAT TGATTTTGGA GGCCTCAAAC CCGCTGGTTC AGAACCAACA 
CCTAAGTCAC GCATTGCAGA CCTTCCTCCT GCCAACCCTG ATCACATCGG TGGATACAGA 
CTCGCCACAG CCACGTTTGC AGGCATCGAA AACAAATTTG GCCTTTATCT CCCGAAATTT 
AAGTCTCCTA GTGTTGCTGT GGTTCAGCCA AAGGCAGCAG TGGCAGCCAC TCAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SLC25A12 ( XM_011512070.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011510372.1 Homo sapiens solute carrier family 25 member 12 (SLC25A12), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu62019
Clone ID Related Accession (Same CDS sequence)	XM_011512070.2 , XM_011512070.3
Accession Version	XM_011512070.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1764bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	calcium-binding mitochondrial carrier protein Aralar1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000002.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011512070.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAACAGG CATGGTGGCA GTCTTGGAGA AGAGTGCCAG CCCCGGTCAG AGAAAATGTC 
AAAGAAATTT TTGGACAGAC TATTATTCAT CATCATATCC CTTTTAACTG GGATTGTGAA 
TTTATCCGAC TGCATTTTGG GCATAACCGG AAGAAGCATC TTAACTACAC AGAATTCACG 
CAGTTTCTCC AGGAGCTGCA ATTGGAACAT GCAAGACAAG CCTTTGCACT CAAAGACAAA 
AGCAAAAGTG GCATGATTTC TGGTCTGGAT TTCAGTGACA TCATGGTTAC CATTAGATCT 
CACATGCTTA CTCCTTTTGT GGAGGAGAAC TTAGTTTCAG CAGCTGGAGG AAGTATCTCA 
CACCAGGTTA GCTTCTCCTA CTTCAATGCA TTTAACTCGT TACTGAATAA CATGGAGCTT 
GTTCGTAAGA TATATAGCAC TCTAGCTGGC ACAAGGAAAG ATGTTGAAGT CACAAAGGAG 
GAATTTGCCC AGAGTGCCAT ACGCTATGGA CAAGTCACAC CACTAGAAAT TGATATTCTA 
TATCAGCTTG CAGACTTATA TAATGCTTCA GGGCGCTTGA CTTTGGCAGA TATTGAGAGA 
ATAGCCCCAT TGGCTGAGGG GGCCTTACCT TACAACCTGG CAGAACTTCA GAGACAGCAG 
TCTCCTGGGT TAGGCAGGCC TATCTGGCTC CAGATTGCCG AGTCTGCTTA CAGATTCACT 
CTGGGCTCAG TTGCTGGAGC TGTGGGAGCC ACTGCAGTGT ATCCTATAGA TCTGGTGAAG 
ACCCGAATGC AAAACCAGCG TGGCTCTGGC TCTGTTGTTG GGGAGCTAAT GTACAAAAAC 
AGCTTTGACT GTTTTAAGAA AGTCTTGCGT TATGAGGGCT TCTTTGGACT CTACAGGGGT 
CTGATACCAC AACTTATAGG GGTTGCTCCA GAAAAGGCCA TTAAACTGAC TGTTAATGAT 
TTTGTTCGGG ACAAATTTAC CAGAAGAGAT GGCTCTGTTC CACTTCCAGC AGAAGTTCTT 
GCTGGAGGCT GTGCTGGAGG CTCTCAGGTC ATTTTTACCA ACCCATTGGA GATAGTGAAG 
ATTCGTCTGC AAGTAGCTGG AGAGATCACC ACGGGACCCA GAGTCAGCGC CCTGAATGTG 
CTCCGGGACT TGGGAATTTT TGGTCTGTAT AAGGGTGCCA AAGCGTGTTT CCTCCGAGAC 
ATTCCCTTCT CTGCAATCTA TTTTCCTGTT TATGCTCATT GCAAACTACT TCTGGCTGAT 
GAAAATGGAC ACGTGGGAGG TTTAAATCTT CTTGCAGCTG GAGCCATGGC AGGTGTCCCA 
GCTGCATCTC TGGTGACCCC TGCTGATGTC ATCAAGACAA GACTGCAGGT GGCTGCCCGC 
GCTGGCCAGA CGACATACAG TGGTGTCATC GACTGTTTCA GGAAGATTCT CCGGGAAGAA 
GGGCCCTCAG CATTTTGGAA AGGGACTGCA GCTCGAGTGT TTCGATCCTC TCCCCAGTTT 
GGTGTTACCT TGGTCACTTA TGAACTTCTC CAGCGGTGGT TTTACATTGA TTTTGGAGGC 
CTCAAACCCG CTGGTTCAGA ACCAACACCT AAGTCACGCA TTGCAGACCT TCCTCCTGCC 
AACCCTGATC ACATCGGTGG ATACAGACTC GCCACAGCCA CGTTTGCAGG CATCGAAAAC 
AAATTTGGCC TTTATCTCCC GAAATTTAAG TCTCCTAGTG TTGCTGTGGT TCAGCCAAAG 
GCAGCAGTGG CAGCCACTCA GTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011510372.1
CDS	438..2201
Translation	MEQAWWQSWRRVPAPVRENVKEIFGQTIIHHHIPFNWDCEFIRLHFGHNRKKHLNYTEFTQFLQELQLEHARQAFALKDKSKSGMISGLDFSDIMVTIRSHMLTPFVEENLVSAAGGSISHQVSFSYFNAFNSLLNNMELVRKIYSTLAGTRKDVEVTKEEFAQSAIRYGQVTPLEIDILYQLADLYNASGRLTLADIERIAPLAEGALPYNLAELQRQQSPGLGRPIWLQIAESAYRFTLGSVAGAVGATAVYPIDLVKTRMQNQRGSGSVVGELMYKNSFDCFKKVLRYEGFFGLYRGLIPQLIGVAPEKAIKLTVNDFVRDKFTRRDGSVPLPAEVLAGGCAGGSQVIFTNPLEIVKIRLQVAGEITTGPRVSALNVLRDLGIFGLYKGAKACFLRDIPFSAIYFPVYAHCKLLLADENGHVGGLNLLAAGAMAGVPAASLVTPADVIKTRLQVAARAGQTTYSGVIDCFRKILREEGPSAFWKGTAARVFRSSPQFGVTLVTYELLQRWFYIDFGGLKPAGSEPTPKSRIADLPPANPDHIGGYRLATATFAGIENKFGLYLPKFKSPSVAVVQPKAAVAATQ

Target ORF information:

RefSeq Version	XM_011512070.2
Organism	Homo sapiens(human)
Definition	Homo sapiens solute carrier family 25 member 12 (SLC25A12), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011512070.2

ORF Insert Sequence:

ATGGAACAGG CATGGTGGCA GTCTTGGAGA AGAGTGCCAG CCCCGGTCAG AGAAAATGTC 
AAAGAAATTT TTGGACAGAC TATTATTCAT CATCATATCC CTTTTAACTG GGATTGTGAA 
TTTATCCGAC TGCATTTTGG GCATAACCGG AAGAAGCATC TTAACTACAC AGAATTCACG 
CAGTTTCTCC AGGAGCTGCA ATTGGAACAT GCAAGACAAG CCTTTGCACT CAAAGACAAA 
AGCAAAAGTG GCATGATTTC TGGTCTGGAT TTCAGTGACA TCATGGTTAC CATTAGATCT 
CACATGCTTA CTCCTTTTGT GGAGGAGAAC TTAGTTTCAG CAGCTGGAGG AAGTATCTCA 
CACCAGGTTA GCTTCTCCTA CTTCAATGCA TTTAACTCGT TACTGAATAA CATGGAGCTT 
GTTCGTAAGA TATATAGCAC TCTAGCTGGC ACAAGGAAAG ATGTTGAAGT CACAAAGGAG 
GAATTTGCCC AGAGTGCCAT ACGCTATGGA CAAGTCACAC CACTAGAAAT TGATATTCTA 
TATCAGCTTG CAGACTTATA TAATGCTTCA GGGCGCTTGA CTTTGGCAGA TATTGAGAGA 
ATAGCCCCAT TGGCTGAGGG GGCCTTACCT TACAACCTGG CAGAACTTCA GAGACAGCAG 
TCTCCTGGGT TAGGCAGGCC TATCTGGCTC CAGATTGCCG AGTCTGCTTA CAGATTCACT 
CTGGGCTCAG TTGCTGGAGC TGTGGGAGCC ACTGCAGTGT ATCCTATAGA TCTGGTGAAG 
ACCCGAATGC AAAACCAGCG TGGCTCTGGC TCTGTTGTTG GGGAGCTAAT GTACAAAAAC 
AGCTTTGACT GTTTTAAGAA AGTCTTGCGT TATGAGGGCT TCTTTGGACT CTACAGGGGT 
CTGATACCAC AACTTATAGG GGTTGCTCCA GAAAAGGCCA TTAAACTGAC TGTTAATGAT 
TTTGTTCGGG ACAAATTTAC CAGAAGAGAT GGCTCTGTTC CACTTCCAGC AGAAGTTCTT 
GCTGGAGGCT GTGCTGGAGG CTCTCAGGTC ATTTTTACCA ACCCATTGGA GATAGTGAAG 
ATTCGTCTGC AAGTAGCTGG AGAGATCACC ACGGGACCCA GAGTCAGCGC CCTGAATGTG 
CTCCGGGACT TGGGAATTTT TGGTCTGTAT AAGGGTGCCA AAGCGTGTTT CCTCCGAGAC 
ATTCCCTTCT CTGCAATCTA TTTTCCTGTT TATGCTCATT GCAAACTACT TCTGGCTGAT 
GAAAATGGAC ACGTGGGAGG TTTAAATCTT CTTGCAGCTG GAGCCATGGC AGGTGTCCCA 
GCTGCATCTC TGGTGACCCC TGCTGATGTC ATCAAGACAA GACTGCAGGT GGCTGCCCGC 
GCTGGCCAGA CGACATACAG TGGTGTCATC GACTGTTTCA GGAAGATTCT CCGGGAAGAA 
GGGCCCTCAG CATTTTGGAA AGGGACTGCA GCTCGAGTGT TTCGATCCTC TCCCCAGTTT 
GGTGTTACCT TGGTCACTTA TGAACTTCTC CAGCGGTGGT TTTACATTGA TTTTGGAGGC 
CTCAAACCCG CTGGTTCAGA ACCAACACCT AAGTCACGCA TTGCAGACCT TCCTCCTGCC 
AACCCTGATC ACATCGGTGG ATACAGACTC GCCACAGCCA CGTTTGCAGG CATCGAAAAC 
AAATTTGGCC TTTATCTCCC GAAATTTAAG TCTCCTAGTG TTGCTGTGGT TCAGCCAAAG 
GCAGCAGTGG CAGCCACTCA GTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SLC25A12 ( XM_011512070.3 ) cDNA ORF clone, Homo sapiens(human) -> XP_011510372.1 Homo sapiens solute carrier family 25 member 12 (SLC25A12), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu62019
Clone ID Related Accession (Same CDS sequence)	XM_011512070.2 , XM_011512070.3
Accession Version	XM_011512070.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1764bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	calcium-binding mitochondrial carrier protein Aralar1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000002.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_011512070.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAACAGG CATGGTGGCA GTCTTGGAGA AGAGTGCCAG CCCCGGTCAG AGAAAATGTC 
AAAGAAATTT TTGGACAGAC TATTATTCAT CATCATATCC CTTTTAACTG GGATTGTGAA 
TTTATCCGAC TGCATTTTGG GCATAACCGG AAGAAGCATC TTAACTACAC AGAATTCACG 
CAGTTTCTCC AGGAGCTGCA ATTGGAACAT GCAAGACAAG CCTTTGCACT CAAAGACAAA 
AGCAAAAGTG GCATGATTTC TGGTCTGGAT TTCAGTGACA TCATGGTTAC CATTAGATCT 
CACATGCTTA CTCCTTTTGT GGAGGAGAAC TTAGTTTCAG CAGCTGGAGG AAGTATCTCA 
CACCAGGTTA GCTTCTCCTA CTTCAATGCA TTTAACTCGT TACTGAATAA CATGGAGCTT 
GTTCGTAAGA TATATAGCAC TCTAGCTGGC ACAAGGAAAG ATGTTGAAGT CACAAAGGAG 
GAATTTGCCC AGAGTGCCAT ACGCTATGGA CAAGTCACAC CACTAGAAAT TGATATTCTA 
TATCAGCTTG CAGACTTATA TAATGCTTCA GGGCGCTTGA CTTTGGCAGA TATTGAGAGA 
ATAGCCCCAT TGGCTGAGGG GGCCTTACCT TACAACCTGG CAGAACTTCA GAGACAGCAG 
TCTCCTGGGT TAGGCAGGCC TATCTGGCTC CAGATTGCCG AGTCTGCTTA CAGATTCACT 
CTGGGCTCAG TTGCTGGAGC TGTGGGAGCC ACTGCAGTGT ATCCTATAGA TCTGGTGAAG 
ACCCGAATGC AAAACCAGCG TGGCTCTGGC TCTGTTGTTG GGGAGCTAAT GTACAAAAAC 
AGCTTTGACT GTTTTAAGAA AGTCTTGCGT TATGAGGGCT TCTTTGGACT CTACAGGGGT 
CTGATACCAC AACTTATAGG GGTTGCTCCA GAAAAGGCCA TTAAACTGAC TGTTAATGAT 
TTTGTTCGGG ACAAATTTAC CAGAAGAGAT GGCTCTGTTC CACTTCCAGC AGAAGTTCTT 
GCTGGAGGCT GTGCTGGAGG CTCTCAGGTC ATTTTTACCA ACCCATTGGA GATAGTGAAG 
ATTCGTCTGC AAGTAGCTGG AGAGATCACC ACGGGACCCA GAGTCAGCGC CCTGAATGTG 
CTCCGGGACT TGGGAATTTT TGGTCTGTAT AAGGGTGCCA AAGCGTGTTT CCTCCGAGAC 
ATTCCCTTCT CTGCAATCTA TTTTCCTGTT TATGCTCATT GCAAACTACT TCTGGCTGAT 
GAAAATGGAC ACGTGGGAGG TTTAAATCTT CTTGCAGCTG GAGCCATGGC AGGTGTCCCA 
GCTGCATCTC TGGTGACCCC TGCTGATGTC ATCAAGACAA GACTGCAGGT GGCTGCCCGC 
GCTGGCCAGA CGACATACAG TGGTGTCATC GACTGTTTCA GGAAGATTCT CCGGGAAGAA 
GGGCCCTCAG CATTTTGGAA AGGGACTGCA GCTCGAGTGT TTCGATCCTC TCCCCAGTTT 
GGTGTTACCT TGGTCACTTA TGAACTTCTC CAGCGGTGGT TTTACATTGA TTTTGGAGGC 
CTCAAACCCG CTGGTTCAGA ACCAACACCT AAGTCACGCA TTGCAGACCT TCCTCCTGCC 
AACCCTGATC ACATCGGTGG ATACAGACTC GCCACAGCCA CGTTTGCAGG CATCGAAAAC 
AAATTTGGCC TTTATCTCCC GAAATTTAAG TCTCCTAGTG TTGCTGTGGT TCAGCCAAAG 
GCAGCAGTGG CAGCCACTCA GTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011510372.1
CDS	408..2171
Translation	MEQAWWQSWRRVPAPVRENVKEIFGQTIIHHHIPFNWDCEFIRLHFGHNRKKHLNYTEFTQFLQELQLEHARQAFALKDKSKSGMISGLDFSDIMVTIRSHMLTPFVEENLVSAAGGSISHQVSFSYFNAFNSLLNNMELVRKIYSTLAGTRKDVEVTKEEFAQSAIRYGQVTPLEIDILYQLADLYNASGRLTLADIERIAPLAEGALPYNLAELQRQQSPGLGRPIWLQIAESAYRFTLGSVAGAVGATAVYPIDLVKTRMQNQRGSGSVVGELMYKNSFDCFKKVLRYEGFFGLYRGLIPQLIGVAPEKAIKLTVNDFVRDKFTRRDGSVPLPAEVLAGGCAGGSQVIFTNPLEIVKIRLQVAGEITTGPRVSALNVLRDLGIFGLYKGAKACFLRDIPFSAIYFPVYAHCKLLLADENGHVGGLNLLAAGAMAGVPAASLVTPADVIKTRLQVAARAGQTTYSGVIDCFRKILREEGPSAFWKGTAARVFRSSPQFGVTLVTYELLQRWFYIDFGGLKPAGSEPTPKSRIADLPPANPDHIGGYRLATATFAGIENKFGLYLPKFKSPSVAVVQPKAAVAATQ

Target ORF information:

RefSeq Version	XM_011512070.3
Organism	Homo sapiens(human)
Definition	Homo sapiens solute carrier family 25 member 12 (SLC25A12), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011512070.3

ORF Insert Sequence:

ATGGAACAGG CATGGTGGCA GTCTTGGAGA AGAGTGCCAG CCCCGGTCAG AGAAAATGTC 
AAAGAAATTT TTGGACAGAC TATTATTCAT CATCATATCC CTTTTAACTG GGATTGTGAA 
TTTATCCGAC TGCATTTTGG GCATAACCGG AAGAAGCATC TTAACTACAC AGAATTCACG 
CAGTTTCTCC AGGAGCTGCA ATTGGAACAT GCAAGACAAG CCTTTGCACT CAAAGACAAA 
AGCAAAAGTG GCATGATTTC TGGTCTGGAT TTCAGTGACA TCATGGTTAC CATTAGATCT 
CACATGCTTA CTCCTTTTGT GGAGGAGAAC TTAGTTTCAG CAGCTGGAGG AAGTATCTCA 
CACCAGGTTA GCTTCTCCTA CTTCAATGCA TTTAACTCGT TACTGAATAA CATGGAGCTT 
GTTCGTAAGA TATATAGCAC TCTAGCTGGC ACAAGGAAAG ATGTTGAAGT CACAAAGGAG 
GAATTTGCCC AGAGTGCCAT ACGCTATGGA CAAGTCACAC CACTAGAAAT TGATATTCTA 
TATCAGCTTG CAGACTTATA TAATGCTTCA GGGCGCTTGA CTTTGGCAGA TATTGAGAGA 
ATAGCCCCAT TGGCTGAGGG GGCCTTACCT TACAACCTGG CAGAACTTCA GAGACAGCAG 
TCTCCTGGGT TAGGCAGGCC TATCTGGCTC CAGATTGCCG AGTCTGCTTA CAGATTCACT 
CTGGGCTCAG TTGCTGGAGC TGTGGGAGCC ACTGCAGTGT ATCCTATAGA TCTGGTGAAG 
ACCCGAATGC AAAACCAGCG TGGCTCTGGC TCTGTTGTTG GGGAGCTAAT GTACAAAAAC 
AGCTTTGACT GTTTTAAGAA AGTCTTGCGT TATGAGGGCT TCTTTGGACT CTACAGGGGT 
CTGATACCAC AACTTATAGG GGTTGCTCCA GAAAAGGCCA TTAAACTGAC TGTTAATGAT 
TTTGTTCGGG ACAAATTTAC CAGAAGAGAT GGCTCTGTTC CACTTCCAGC AGAAGTTCTT 
GCTGGAGGCT GTGCTGGAGG CTCTCAGGTC ATTTTTACCA ACCCATTGGA GATAGTGAAG 
ATTCGTCTGC AAGTAGCTGG AGAGATCACC ACGGGACCCA GAGTCAGCGC CCTGAATGTG 
CTCCGGGACT TGGGAATTTT TGGTCTGTAT AAGGGTGCCA AAGCGTGTTT CCTCCGAGAC 
ATTCCCTTCT CTGCAATCTA TTTTCCTGTT TATGCTCATT GCAAACTACT TCTGGCTGAT 
GAAAATGGAC ACGTGGGAGG TTTAAATCTT CTTGCAGCTG GAGCCATGGC AGGTGTCCCA 
GCTGCATCTC TGGTGACCCC TGCTGATGTC ATCAAGACAA GACTGCAGGT GGCTGCCCGC 
GCTGGCCAGA CGACATACAG TGGTGTCATC GACTGTTTCA GGAAGATTCT CCGGGAAGAA 
GGGCCCTCAG CATTTTGGAA AGGGACTGCA GCTCGAGTGT TTCGATCCTC TCCCCAGTTT 
GGTGTTACCT TGGTCACTTA TGAACTTCTC CAGCGGTGGT TTTACATTGA TTTTGGAGGC 
CTCAAACCCG CTGGTTCAGA ACCAACACCT AAGTCACGCA TTGCAGACCT TCCTCCTGCC 
AACCCTGATC ACATCGGTGG ATACAGACTC GCCACAGCCA CGTTTGCAGG CATCGAAAAC 
AAATTTGGCC TTTATCTCCC GAAATTTAAG TCTCCTAGTG TTGCTGTGGT TCAGCCAAAG 
GCAGCAGTGG CAGCCACTCA GTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Single Nucleotide Polymorphisms in SLC19A1 and SLC25A9 Are Associated with Childhood Autism Spectrum Disorder in the Chinese Han Population.
Journal of molecular neuroscience : MN62(2)262-267(2017 Jun)
Liu J,Mo W,Zhang Z,Yu H,Yang A,Qu F,Hu P,Liu Z,Wang S

AGC1/2, the mitochondrial aspartate-glutamate carriers.
Biochimica et biophysica acta1863(10)2394-412(2016 10)
Amoedo ND,Punzi G,Obre E,Lacombe D,De Grassi A,Pierri CL,Rossignol R

Mitochondrial Aspartate/Glutamate Carrier SLC25A12 and Autism Spectrum Disorder: a Meta-Analysis.
Molecular neurobiology53(3)1579-1588(2016 Apr)
Aoki Y,Cortese S

Association between genetic variants in SLC25A12 and risk of autism spectrum disorders: An integrated meta-analysis.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics168B(4)236-46(2015 Jun)
Liu J,Yang A,Zhang Q,Yang G,Yang W,Lei H,Quan J,Qu F,Wang M,Zhang Z,Yu K

Calcium-induced conformational changes of the regulatory domain of human mitochondrial aspartate/glutamate carriers.
Nature communications55491(2014 Nov)
Thangaratnarajah C,Ruprecht JJ,Kunji ER

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SLC25A12 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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