ZIC5 cDNA ORF clone, Homo sapiens(Human)

Gene
Clones
gRNAs

Summary

Gene Symbol	ZIC5
Entrez Gene ID	85416
Full Name	Zic family member 5
General protein information	Preferred Names Zic family member 5 Names zinc finger protein ZIC 5 Zic family member 5 (odd-paired homolog, Drosophila) zinc finger protein of the cerebellum 5
Gene Type	protein-coding
Organism	Homo sapiens(Human)
Genome	Chromosome: 13 Map Location: 13q32.3
Summary	This gene encodes a member of the ZIC family of C2H2-type zinc finger proteins. The encoded protein may act as a transcriptional repressor. Studies in mouse and Xenopus support a role for this gene in neural crest development. Elevated expression of this gene has been observed in various human cancers and may contribute to cancer progression. This gene is closely linked to a related family member on chromosome 13. [provided by RefSeq, Mar 2017].

mRNA and Protein(s)

mRNA	Protein	Name
NM_033132.4	NP_149123.2	zinc finger protein ZIC 5
NM_033132.3	NP_149123.2	zinc finger protein ZIC 5

Pathways from BioSystems

Homologies

Homo sapiens (human)	ZIC5	NP_149123.2
	LOC705141	XP_001093521.2
Mus musculus (house mouse)	Zic5	NP_075363.1
Canis lupus familiaris (dog)	ZIC5	XP_854266.2
Rattus norvegicus (Norway rat)	Zic5	NP_001101861.1

Gene Ontology
Bibliography

Related articles in PubMed

Identification of zinc finger protein of the cerebellum 5 as a survival factor of prostate and colorectal cancer cells.
Satow R, Inagaki S, Kato C, Shimozawa M, Fukami K
Cancer science108(12)2405-2412(2017 Dec)

ZIC5 Drives Melanoma Aggressiveness by PDGFD-Mediated Activation of FAK and STAT3.
Satow R, Nakamura T, Kato C, Endo M, Tamura M, Batori R, Tomura S, Murayama Y, Fukami K
Cancer research77(2)366-377(2017 Jan)

Overexpression of ZIC5 promotes proliferation in non-small cell lung cancer.
Sun Q, Shi R, Wang X, Li D, Wu H, Ren B
Biochemical and biophysical research communications479(3)502-509(2016 Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

ZIC5 positively regulated the proliferation, migration, and survival of prostate colorectal cancer cells
Title: Identification of zinc finger protein of the cerebellum 5 as a survival factor of prostate and colorectal cancer cells.

ZIC5 is highly upregulated in non-small cell lung cancer tumor tissues and may act as an oncogene by influencing CCNB1 and CDK1 complex expression
Title: Overexpression of ZIC5 promotes proliferation in non-small cell lung cancer.

the smallest 13q deletion associated to DWM allows further narrowing of the previously established critical region for this brain malformation to 13q32.2-32.3. Among the few genes of the deleted region, ZIC2 and ZIC5 seem the most plausible candidates.
Title: Description of the smallest critical region for Dandy-Walker malformation in chromosome 13 in a girl with a cryptic deletion related to t(6;13)(q23;q32).

ZIC1, ZIC2, and ZIC5 may have roles in meningiomas
Title: Expression of ZIC family genes in meningiomas and other brain tumors.

The following ZIC5 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the ZIC5 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu29982	NM_033132.4 Latest version!	Homo sapiens Zic family member 5 (ZIC5), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$307.30 $439.00
View Old Accession Versions >>
OHu29982	NM_033132.3	Homo sapiens Zic family member 5 (ZIC5), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$307.30 $439.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

ZIC5 ( NM_033132.4 ) cDNA ORF clone, Homo sapiens(Human) -> NP_149123.2 Homo sapiens Zic family member 5 (ZIC5), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu29982
Clone ID Related Accession (Same CDS sequence)	NM_033132.4 , NM_033132.3
Accession Version	NM_033132.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1992bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-25
Organism	Homo sapiens(human)
Product	zinc finger protein ZIC 5
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AF378304.1, AL355338.33 and CB129979.1. This sequence is a reference standard in the RefSeqGene project. On Mar 25, 2017 this sequence version replaced NM_033132.3. Transcript Variant: This variant (1) encodes the protein. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF378304.1, SRR1660803.29887.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA2145743 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGTTTTTGA AGGCGGGCAG AGGGAATAAA GTCCCCCCAG TGAGGGTCTA TGGGCCTGAT 
TGTGTAGTTC TGATGGAGCC CCCTTTGAGC AAGAGGAACC CGCCAGCGCT GAGATTAGCG 
GATTTGGCAA CGGCTCAGGT CCAGCCGCTT CAGAATATGA CAGGCTTCCC GGCGCTGGCC 
GGCCCGCCCG CCCACTCCCA ACTCCGGGCC GCCGTCGCGC ACCTCCGCCT GCGGGACCTG 
GGCGCTGACC CCGGCGTGGC CACCACTCCG CTCGGACCCG AGCACATGGC CCAGGCGAGC 
ACGCTGGGCC TCAGCCCTCC CTCCCAGGCG TTCCCGGCAC ACCCGGAGGC TCCGGCAGCC 
GCCGCCCGTG CTGCAGCCTT GGTCGCGCAC CCCGGCGCGG GCAGCTACCC CTGCGGCGGG 
GGCAGCAGTG GCGCGCAGCC CTCCGCGCCC CCGCCCCCAG CCCCTCCTCT TCCTCCCACC 
CCTTCACCCC CTCCCCCTCC CCCGCCTCCT CCTCCTCCTG CCCTCTCGGG CTACACCACC 
ACCAACAGTG GCGGCGGCGG CAGCAGCGGC AAAGGCCACA GCAGGGACTT CGTCCTCCGG 
AGGGACCTTT CCGCCACGGC CCCCGCGGCG GCCATGCACG GGGCCCCGCT CGGAGGGGAG 
CAGCGGTCCG GCACCGGCTC CCCCCAGCAC CCGGCCCCGC CTCCCCACTC GGCCGGCATG 
TTCATCTCCG CCAGCGGCAC CTACGCGGGC CCGGACGGCA GCGGCGGCCC GGCGCTCTTC 
CCCGCGCTGC ACGACACGCC GGGGGCCCCA GGCGGCCACC CGCACCCGCT CAACGGCCAG 
ATGCGCCTGG GGCTGGCGGC GGCAGCGGCA GCCGCGGCGG CTGAGCTGTA CGGCCGCGCC 
GAACCGCCCT TCGCGCCGCG CTCTGGGGAC GCGCACTACG GGGCGGTTGC GGCCGCAGCG 
GCGGCCGCCC TGCACGGCTA CGGAGCCGTG AACTTAAACC TGAACCTGGC GGCTGCGGCG 
GCCGCAGCAG CGGCCGGGCC CGGGCCCCAC CTGCAGCACC ACGCGCCGCC CCCGGCGCCG 
CCGCCGCCGC CGGCGCCCGC GCAGCACCCG CACCAGCACC ACCCCCACCT CCCAGGGGCG 
GCTGGGGCCT TCCTGCGCTA CATGCGGCAG CCAATCAAGC AGGAGCTCAT CTGCAAGTGG 
ATCGACCCCG ACGAGCTGGC CGGGCTGCCG CCGCCGCCGC CGCCGCCGCC GCCGCCGCCG 
CCACCGCCCC CGGCCGGCGG CGCCAAGCCC TGCTCCAAAA CTTTCGGCAC CATGCACGAG 
CTGGTGAATC ACGTCACGGT GGAGCACGTG GGAGGCCCCG AGCAGAGCAG CCACGTCTGC 
TTCTGGGAGG ACTGTCCGCG CGAGGGCAAG CCCTTCAAGG CCAAATACAA GCTCATCAAC 
CACATCCGCG TGCACACCGG CGAGAAGCCC TTTCCCTGCC CTTTCCCCGG CTGCGGCAAG 
GTCTTCGCGC GCTCCGAGAA CCTCAAGATC CACAAGCGTA CTCATACAGG GGAAAAGCCT 
TTCAAATGTG AATTTGATGG CTGTGACAGG AAGTTTGCCA ATAGCAGTGA TCGGAAGAAA 
CATTCCCATG TCCACACCAG TGACAAGCCC TACTACTGCA AGATTCGAGG CTGTGACAAA 
TCCTACACTC ACCCAAGCTC CCTGAGGAAG CACATGAAGA TTCACTGCAA GTCCCCGCCA 
CCTTCTCCAG GACCCCTTGG TTACTCATCA GTGGGGACTC CAGTGGGCGC CCCCTTGTCC 
CCTGTGCTGG ACCCAGCCAG GAGTCACTCC AGCACTCTGT CCCCTCAGGT GACCAACCTC 
AATGAGTGGT ACGTTTGCCA GGCCAGTGGG GCCCCCAGCC ACCTCCACAC CCCTTCCAGC 
AACGGAACCA CCTCTGAGAC TGAAGATGAG GAAATTTACG GGAACCCTGA AGTTGTGCGG 
ACGATACATT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_149123.2
CDS	235..2226
Translation	MFLKAGRGNKVPPVRVYGPDCVVLMEPPLSKRNPPALRLADLATAQVQPLQNMTGFPALAGPPAHSQLRAAVAHLRLRDLGADPGVATTPLGPEHMAQASTLGLSPPSQAFPAHPEAPAAAARAAALVAHPGAGSYPCGGGSSGAQPSAPPPPAPPLPPTPSPPPPPPPPPPPALSGYTTTNSGGGGSSGKGHSRDFVLRRDLSATAPAAAMHGAPLGGEQRSGTGSPQHPAPPPHSAGMFISASGTYAGPDGSGGPALFPALHDTPGAPGGHPHPLNGQMRLGLAAAAAAAAAELYGRAEPPFAPRSGDAHYGAVAAAAAAALHGYGAVNLNLNLAAAAAAAAAGPGPHLQHHAPPPAPPPPPAPAQHPHQHHPHLPGAAGAFLRYMRQPIKQELICKWIDPDELAGLPPPPPPPPPPPPPPPAGGAKPCSKTFGTMHELVNHVTVEHVGGPEQSSHVCFWEDCPREGKPFKAKYKLINHIRVHTGEKPFPCPFPGCGKVFARSENLKIHKRTHTGEKPFKCEFDGCDRKFANSSDRKKHSHVHTSDKPYYCKIRGCDKSYTHPSSLRKHMKIHCKSPPPSPGPLGYSSVGTPVGAPLSPVLDPARSHSSTLSPQVTNLNEWYVCQASGAPSHLHTPSSNGTTSETEDEEIYGNPEVVRTIH

Target ORF information:

RefSeq Version	NM_033132.4
Organism	Homo sapiens(human)
Definition	Homo sapiens Zic family member 5 (ZIC5), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_033132.4

ORF Insert Sequence:

ATGTTTTTGA AGGCGGGCAG AGGGAATAAA GTCCCCCCAG TGAGGGTCTA TGGGCCTGAT 
TGTGTAGTTC TGATGGAGCC CCCTTTGAGC AAGAGGAACC CGCCAGCGCT GAGATTAGCG 
GATTTGGCAA CGGCTCAGGT CCAGCCGCTT CAGAATATGA CAGGCTTCCC GGCGCTGGCC 
GGCCCGCCCG CCCACTCCCA ACTCCGGGCC GCCGTCGCGC ACCTCCGCCT GCGGGACCTG 
GGCGCTGACC CCGGCGTGGC CACCACTCCG CTCGGACCCG AGCACATGGC CCAGGCGAGC 
ACGCTGGGCC TCAGCCCTCC CTCCCAGGCG TTCCCGGCAC ACCCGGAGGC TCCGGCAGCC 
GCCGCCCGTG CTGCAGCCTT GGTCGCGCAC CCCGGCGCGG GCAGCTACCC CTGCGGCGGG 
GGCAGCAGTG GCGCGCAGCC CTCCGCGCCC CCGCCCCCAG CCCCTCCTCT TCCTCCCACC 
CCTTCACCCC CTCCCCCTCC CCCGCCTCCT CCTCCTCCTG CCCTCTCGGG CTACACCACC 
ACCAACAGTG GCGGCGGCGG CAGCAGCGGC AAAGGCCACA GCAGGGACTT CGTCCTCCGG 
AGGGACCTTT CCGCCACGGC CCCCGCGGCG GCCATGCACG GGGCCCCGCT CGGAGGGGAG 
CAGCGGTCCG GCACCGGCTC CCCCCAGCAC CCGGCCCCGC CTCCCCACTC GGCCGGCATG 
TTCATCTCCG CCAGCGGCAC CTACGCGGGC CCGGACGGCA GCGGCGGCCC GGCGCTCTTC 
CCCGCGCTGC ACGACACGCC GGGGGCCCCA GGCGGCCACC CGCACCCGCT CAACGGCCAG 
ATGCGCCTGG GGCTGGCGGC GGCAGCGGCA GCCGCGGCGG CTGAGCTGTA CGGCCGCGCC 
GAACCGCCCT TCGCGCCGCG CTCTGGGGAC GCGCACTACG GGGCGGTTGC GGCCGCAGCG 
GCGGCCGCCC TGCACGGCTA CGGAGCCGTG AACTTAAACC TGAACCTGGC GGCTGCGGCG 
GCCGCAGCAG CGGCCGGGCC CGGGCCCCAC CTGCAGCACC ACGCGCCGCC CCCGGCGCCG 
CCGCCGCCGC CGGCGCCCGC GCAGCACCCG CACCAGCACC ACCCCCACCT CCCAGGGGCG 
GCTGGGGCCT TCCTGCGCTA CATGCGGCAG CCAATCAAGC AGGAGCTCAT CTGCAAGTGG 
ATCGACCCCG ACGAGCTGGC CGGGCTGCCG CCGCCGCCGC CGCCGCCGCC GCCGCCGCCG 
CCACCGCCCC CGGCCGGCGG CGCCAAGCCC TGCTCCAAAA CTTTCGGCAC CATGCACGAG 
CTGGTGAATC ACGTCACGGT GGAGCACGTG GGAGGCCCCG AGCAGAGCAG CCACGTCTGC 
TTCTGGGAGG ACTGTCCGCG CGAGGGCAAG CCCTTCAAGG CCAAATACAA GCTCATCAAC 
CACATCCGCG TGCACACCGG CGAGAAGCCC TTTCCCTGCC CTTTCCCCGG CTGCGGCAAG 
GTCTTCGCGC GCTCCGAGAA CCTCAAGATC CACAAGCGTA CTCATACAGG GGAAAAGCCT 
TTCAAATGTG AATTTGATGG CTGTGACAGG AAGTTTGCCA ATAGCAGTGA TCGGAAGAAA 
CATTCCCATG TCCACACCAG TGACAAGCCC TACTACTGCA AGATTCGAGG CTGTGACAAA 
TCCTACACTC ACCCAAGCTC CCTGAGGAAG CACATGAAGA TTCACTGCAA GTCCCCGCCA 
CCTTCTCCAG GACCCCTTGG TTACTCATCA GTGGGGACTC CAGTGGGCGC CCCCTTGTCC 
CCTGTGCTGG ACCCAGCCAG GAGTCACTCC AGCACTCTGT CCCCTCAGGT GACCAACCTC 
AATGAGTGGT ACGTTTGCCA GGCCAGTGGG GCCCCCAGCC ACCTCCACAC CCCTTCCAGC 
AACGGAACCA CCTCTGAGAC TGAAGATGAG GAAATTTACG GGAACCCTGA AGTTGTGCGG 
ACGATACATT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ZIC5 ( NM_033132.3 ) cDNA ORF clone, Homo sapiens(Human) -> NP_149123.2 Homo sapiens Zic family member 5 (ZIC5), mRNA.

Price & Availability↑

CloneID	OHu29982
Clone ID Related Accession (Same CDS sequence)	NM_033132.4 , NM_033132.3
Accession Version	NM_033132.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1992bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2015-03-14
Organism	Homo sapiens(Human)
Product	zinc finger protein ZIC 5
Comment

ATGTTTTTGA AGGCGGGCAG AGGGAATAAA GTCCCCCCAG TGAGGGTCTA TGGGCCTGAT 
TGTGTAGTTC TGATGGAGCC CCCTTTGAGC AAGAGGAACC CGCCAGCGCT GAGATTAGCG 
GATTTGGCAA CGGCTCAGGT CCAGCCGCTT CAGAATATGA CAGGCTTCCC GGCGCTGGCC 
GGCCCGCCCG CCCACTCCCA ACTCCGGGCC GCCGTCGCGC ACCTCCGCCT GCGGGACCTG 
GGCGCTGACC CCGGCGTGGC CACCACTCCG CTCGGACCCG AGCACATGGC CCAGGCGAGC 
ACGCTGGGCC TCAGCCCTCC CTCCCAGGCG TTCCCGGCAC ACCCGGAGGC TCCGGCAGCC 
GCCGCCCGTG CTGCAGCCTT GGTCGCGCAC CCCGGCGCGG GCAGCTACCC CTGCGGCGGG 
GGCAGCAGTG GCGCGCAGCC CTCCGCGCCC CCGCCCCCAG CCCCTCCTCT TCCTCCCACC 
CCTTCACCCC CTCCCCCTCC CCCGCCTCCT CCTCCTCCTG CCCTCTCGGG CTACACCACC 
ACCAACAGTG GCGGCGGCGG CAGCAGCGGC AAAGGCCACA GCAGGGACTT CGTCCTCCGG 
AGGGACCTTT CCGCCACGGC CCCCGCGGCG GCCATGCACG GGGCCCCGCT CGGAGGGGAG 
CAGCGGTCCG GCACCGGCTC CCCCCAGCAC CCGGCCCCGC CTCCCCACTC GGCCGGCATG 
TTCATCTCCG CCAGCGGCAC CTACGCGGGC CCGGACGGCA GCGGCGGCCC GGCGCTCTTC 
CCCGCGCTGC ACGACACGCC GGGGGCCCCA GGCGGCCACC CGCACCCGCT CAACGGCCAG 
ATGCGCCTGG GGCTGGCGGC GGCAGCGGCA GCCGCGGCGG CTGAGCTGTA CGGCCGCGCC 
GAACCGCCCT TCGCGCCGCG CTCTGGGGAC GCGCACTACG GGGCGGTTGC GGCCGCAGCG 
GCGGCCGCCC TGCACGGCTA CGGAGCCGTG AACTTAAACC TGAACCTGGC GGCTGCGGCG 
GCCGCAGCAG CGGCCGGGCC CGGGCCCCAC CTGCAGCACC ACGCGCCGCC CCCGGCGCCG 
CCGCCGCCGC CGGCGCCCGC GCAGCACCCG CACCAGCACC ACCCCCACCT CCCAGGGGCG 
GCTGGGGCCT TCCTGCGCTA CATGCGGCAG CCAATCAAGC AGGAGCTCAT CTGCAAGTGG 
ATCGACCCCG ACGAGCTGGC CGGGCTGCCG CCGCCGCCGC CGCCGCCGCC GCCGCCGCCG 
CCACCGCCCC CGGCCGGCGG CGCCAAGCCC TGCTCCAAAA CTTTCGGCAC CATGCACGAG 
CTGGTGAATC ACGTCACGGT GGAGCACGTG GGAGGCCCCG AGCAGAGCAG CCACGTCTGC 
TTCTGGGAGG ACTGTCCGCG CGAGGGCAAG CCCTTCAAGG CCAAATACAA GCTCATCAAC 
CACATCCGCG TGCACACCGG CGAGAAGCCC TTTCCCTGCC CTTTCCCCGG CTGCGGCAAG 
GTCTTCGCGC GCTCCGAGAA CCTCAAGATC CACAAGCGTA CTCATACAGG GGAAAAGCCT 
TTCAAATGTG AATTTGATGG CTGTGACAGG AAGTTTGCCA ATAGCAGTGA TCGGAAGAAA 
CATTCCCATG TCCACACCAG TGACAAGCCC TACTACTGCA AGATTCGAGG CTGTGACAAA 
TCCTACACTC ACCCAAGCTC CCTGAGGAAG CACATGAAGA TTCACTGCAA GTCCCCGCCA 
CCTTCTCCAG GACCCCTTGG TTACTCATCA GTGGGGACTC CAGTGGGCGC CCCCTTGTCC 
CCTGTGCTGG ACCCAGCCAG GAGTCACTCC AGCACTCTGT CCCCTCAGGT GACCAACCTC 
AATGAGTGGT ACGTTTGCCA GGCCAGTGGG GCCCCCAGCC ACCTCCACAC CCCTTCCAGC 
AACGGAACCA CCTCTGAGAC TGAAGATGAG GAAATTTACG GGAACCCTGA AGTTGTGCGG 
ACGATACATT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq

NP_149123.2

Translation

MFLKAGRGNKVPPVRVYGPDCVVLMEPPLSKRNPPALRLADLATAQVQPLQNMTGFPALAGPPAHSQLRAAVAHLRLRDLGADPGVATTPLGPEHMAQASTLGLSPPSQAFPAHPEAPAAAARAAALVAHPGAGSYPCGGGSSGAQPSAPPPPAPPLPPTPSPPPPPPPPPPPALSGYTTTNSGGGGSSGKGHSRDFVLRRDLSATAPAAAMHGAPLGGEQRSGTGSPQHPAPPPHSAGMFISASGTYAGPDGSGGPALFPALHDTPGAPGGHPHPLNGQMRLGLAAAAAAAAAELYGRAEPPFAPRSGDAHYGAVAAAAAAALHGYGAVNLNLNLAAAAAAAAAGPGPHLQHHAPPPAPPPPPAPAQHPHQHHPHLPGAAGAFLRYMRQPIKQELICKWIDPDELAGLPPPPPPPPPPPPPPPAGGAKPCSKTFGTMHELVNHVTVEHVGGPEQSSHVCFWEDCPREGKPFKAKYKLINHIRVHTGEKPFPCPFPGCGKVFARSENLKIHKRTHTGEKPFKCEFDGCDRKFANSSDRKKHSHVHTSDKPYYCKIRGCDKSYTHPSSLRKHMKIHCKSPPPSPGPLGYSSVGTPVGAPLSPVLDPARSHSSTLSPQVTNLNEWYVCQASGAPSHLHTPSSNGTTSETEDEEIYGNPEVVRTIH

Target ORF information:

RefSeq Version	NM_033132.3
Organism	Homo sapiens(Human)
Definition	Homo sapiens Zic family member 5 (ZIC5), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_033132.3

ORF Insert Sequence:

ATGTTTTTGA AGGCGGGCAG AGGGAATAAA GTCCCCCCAG TGAGGGTCTA TGGGCCTGAT 
TGTGTAGTTC TGATGGAGCC CCCTTTGAGC AAGAGGAACC CGCCAGCGCT GAGATTAGCG 
GATTTGGCAA CGGCTCAGGT CCAGCCGCTT CAGAATATGA CAGGCTTCCC GGCGCTGGCC 
GGCCCGCCCG CCCACTCCCA ACTCCGGGCC GCCGTCGCGC ACCTCCGCCT GCGGGACCTG 
GGCGCTGACC CCGGCGTGGC CACCACTCCG CTCGGACCCG AGCACATGGC CCAGGCGAGC 
ACGCTGGGCC TCAGCCCTCC CTCCCAGGCG TTCCCGGCAC ACCCGGAGGC TCCGGCAGCC 
GCCGCCCGTG CTGCAGCCTT GGTCGCGCAC CCCGGCGCGG GCAGCTACCC CTGCGGCGGG 
GGCAGCAGTG GCGCGCAGCC CTCCGCGCCC CCGCCCCCAG CCCCTCCTCT TCCTCCCACC 
CCTTCACCCC CTCCCCCTCC CCCGCCTCCT CCTCCTCCTG CCCTCTCGGG CTACACCACC 
ACCAACAGTG GCGGCGGCGG CAGCAGCGGC AAAGGCCACA GCAGGGACTT CGTCCTCCGG 
AGGGACCTTT CCGCCACGGC CCCCGCGGCG GCCATGCACG GGGCCCCGCT CGGAGGGGAG 
CAGCGGTCCG GCACCGGCTC CCCCCAGCAC CCGGCCCCGC CTCCCCACTC GGCCGGCATG 
TTCATCTCCG CCAGCGGCAC CTACGCGGGC CCGGACGGCA GCGGCGGCCC GGCGCTCTTC 
CCCGCGCTGC ACGACACGCC GGGGGCCCCA GGCGGCCACC CGCACCCGCT CAACGGCCAG 
ATGCGCCTGG GGCTGGCGGC GGCAGCGGCA GCCGCGGCGG CTGAGCTGTA CGGCCGCGCC 
GAACCGCCCT TCGCGCCGCG CTCTGGGGAC GCGCACTACG GGGCGGTTGC GGCCGCAGCG 
GCGGCCGCCC TGCACGGCTA CGGAGCCGTG AACTTAAACC TGAACCTGGC GGCTGCGGCG 
GCCGCAGCAG CGGCCGGGCC CGGGCCCCAC CTGCAGCACC ACGCGCCGCC CCCGGCGCCG 
CCGCCGCCGC CGGCGCCCGC GCAGCACCCG CACCAGCACC ACCCCCACCT CCCAGGGGCG 
GCTGGGGCCT TCCTGCGCTA CATGCGGCAG CCAATCAAGC AGGAGCTCAT CTGCAAGTGG 
ATCGACCCCG ACGAGCTGGC CGGGCTGCCG CCGCCGCCGC CGCCGCCGCC GCCGCCGCCG 
CCACCGCCCC CGGCCGGCGG CGCCAAGCCC TGCTCCAAAA CTTTCGGCAC CATGCACGAG 
CTGGTGAATC ACGTCACGGT GGAGCACGTG GGAGGCCCCG AGCAGAGCAG CCACGTCTGC 
TTCTGGGAGG ACTGTCCGCG CGAGGGCAAG CCCTTCAAGG CCAAATACAA GCTCATCAAC 
CACATCCGCG TGCACACCGG CGAGAAGCCC TTTCCCTGCC CTTTCCCCGG CTGCGGCAAG 
GTCTTCGCGC GCTCCGAGAA CCTCAAGATC CACAAGCGTA CTCATACAGG GGAAAAGCCT 
TTCAAATGTG AATTTGATGG CTGTGACAGG AAGTTTGCCA ATAGCAGTGA TCGGAAGAAA 
CATTCCCATG TCCACACCAG TGACAAGCCC TACTACTGCA AGATTCGAGG CTGTGACAAA 
TCCTACACTC ACCCAAGCTC CCTGAGGAAG CACATGAAGA TTCACTGCAA GTCCCCGCCA 
CCTTCTCCAG GACCCCTTGG TTACTCATCA GTGGGGACTC CAGTGGGCGC CCCCTTGTCC 
CCTGTGCTGG ACCCAGCCAG GAGTCACTCC AGCACTCTGT CCCCTCAGGT GACCAACCTC 
AATGAGTGGT ACGTTTGCCA GGCCAGTGGG GCCCCCAGCC ACCTCCACAC CCCTTCCAGC 
AACGGAACCA CCTCTGAGAC TGAAGATGAG GAAATTTACG GGAACCCTGA AGTTGTGCGG 
ACGATACATT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Identification of zinc finger protein of the cerebellum 5 as a survival factor of prostate and colorectal cancer cells.
Cancer science108(12)2405-2412(2017 Dec)
Satow R,Inagaki S,Kato C,Shimozawa M,Fukami K

ZIC5 Drives Melanoma Aggressiveness by PDGFD-Mediated Activation of FAK and STAT3.
Cancer research77(2)366-377(2017 Jan)
Satow R,Nakamura T,Kato C,Endo M,Tamura M,Batori R,Tomura S,Murayama Y,Fukami K

Overexpression of ZIC5 promotes proliferation in non-small cell lung cancer.
Biochemical and biophysical research communications479(3)502-509(2016 Oct)
Sun Q,Shi R,Wang X,Li D,Wu H,Ren B

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ZIC5 cDNA ORF clone, Homo sapiens(Human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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