AGPS cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	AGPS
Entrez Gene ID	8540
Full Name	alkylglycerone phosphate synthase
Synonyms	ADAP-S,ADAS,ADHAPS,ADPS,ALDHPSY,RCDP3
General protein information	Preferred Names alkylglycerone phosphate synthase Names alkyldihydroxyacetonephosphate synthase, peroxisomal aging-associated gene 5 protein aging-associated protein 5 alkyl-DHAP synthase
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 2 Map Location: 2q31.2
Summary	This gene is a member of the FAD-binding oxidoreductase/transferase type 4 family. It encodes a protein that catalyzes the second step of ether lipid biosynthesis in which acyl-dihydroxyacetonephosphate (DHAP) is converted to alkyl-DHAP by the addition of a long chain alcohol and the removal of a long-chain acid anion. The protein is localized to the inner aspect of the peroxisomal membrane and requires FAD as a cofactor. Mutations in this gene have been associated with rhizomelic chondrodysplasia punctata, type 3 and Zellweger syndrome. [provided by RefSeq, Jul 2008].
Disorder MIM:	603051
Disorder Html:	Rhizomelic chondrodysplasia punctata, type 3, 600121 (3)

mRNA and Protein(s)

mRNA	Protein	Name
XM_011512042.1	XP_011510344.1	alkyldihydroxyacetonephosphate synthase, peroxisomal isoform X1
XM_011512043.2	XP_011510345.1	alkyldihydroxyacetonephosphate synthase, peroxisomal isoform X2
NM_003659.4	NP_003650.1	alkyldihydroxyacetonephosphate synthase, peroxisomal precursor
XM_011512041.2	XP_011510343.1	alkyldihydroxyacetonephosphate synthase, peroxisomal isoform X1
NM_003659.3	NP_003650.1	alkyldihydroxyacetonephosphate synthase, peroxisomal precursor

Pathways from BioSystems

Homologies

Mus musculus (house mouse)	Agps	NP_766254.2
Homo sapiens (human)	AGPS	NP_003650.1
Bos taurus (cattle)	AGPS	NP_001193648.1
Rattus norvegicus (Norway rat)	Agps	NP_445802.2
Drosophila melanogaster (fruit fly)	CG10253	NP_001188935.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP004358	XP_313642.2
Xenopus tropicalis (tropical clawed frog)	agps	NP_001120301.1
Pan troglodytes (chimpanzee)	AGPS	XP_001154263.3
Canis lupus familiaris (dog)	AGPS	XP_545543.2
	AGPS	XP_002799004.1
Gallus gallus (chicken)	AGPS	XP_421987.3
Caenorhabditis elegans (roundworm)	ads-1	NP_497185.1
Danio rerio (zebrafish)	agps	NP_956407.1

Gene Ontology
Bibliography

Related articles in PubMed

The effect of benzyl isothiocyanate and its computer-aided design derivants targeting alkylglycerone phosphate synthase on the inhibition of human glioma U87MG cell line.
Zhu Y, Liu A, Zhang X, Qi L, Zhang L, Xue J, Liu Y, Yang P
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine36(5)3499-509(2015 May)

Role and mechanism of the alkylglycerone phosphate synthase in suppressing the invasion potential of human glioma and hepatic carcinoma cells in vitro.
Zhu Y, Zhu L, Lu L, Zhang L, Zhang G, Wang Q, Yang P
Oncology reports32(1)431-6(2014 Jul)

Alkylglyceronephosphate synthase (AGPS) alters lipid signaling pathways and supports chemotherapy resistance of glioma and hepatic carcinoma cell lines.
Zhu Y, Liu XJ, Yang P, Zhao M, Lv LX, Zhang GD, Wang Q, Zhang L
Asian Pacific journal of cancer prevention : APJCP15(7)3219-26(2014)

Ether lipid generating enzyme AGPS alters the balance of structural and signaling lipids to fuel cancer pathogenicity.
Benjamin DI, Cozzo A, Ji X, Roberts LS, Louie SM, Mulvihill MM, Luo K, Nomura DK
Proceedings of the National Academy of Sciences of the United States of America110(37)14912-7(2013 Sep)

Functional characterization of novel mutations in GNPAT and AGPS, causing rhizomelic chondrodysplasia punctata (RCDP) types 2 and 3.
Itzkovitz B, Jiralerspong S, Nimmo G, Loscalzo M, Horovitz DD, Snowden A, Moser A, Steinberg S, Braverman N
Human mutation33(1)189-97(2012 Jan)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

we optimized the BITC construction targeting alkylglycerone phosphate synthase (AGPS) by computer-aided design, and the derivants also showed anti-tumor potential in vitro.
Title: The effect of benzyl isothiocyanate and its computer-aided design derivants targeting alkylglycerone phosphate synthase on the inhibition of human glioma U87MG cell line.

Results demonstrated that AGPS negatively regulated the invasion potential of glioma and hepatic carcinoma cells by modulating the expression of relevant genes and activity of the MAPK pathway.
Title: Role and mechanism of the alkylglycerone phosphate synthase in suppressing the invasion potential of human glioma and hepatic carcinoma cells in vitro.

AGPS overexpression could be a causation of chemotherapy agent resistance of cancer cells. AGPS silencing could lead to drug uptake and cell cycle arrest and apoptotic cell death.
Title: Alkylglyceronephosphate synthase (AGPS) alters lipid signaling pathways and supports chemotherapy resistance of glioma and hepatic carcinoma cell lines.

AGPS, in addition to maintaining ether lipids, also controls cellular utilization of fatty acids, favoring the generation of signaling lipids necessary for promoting the aggressive features of cancer.
Title: Ether lipid generating enzyme AGPS alters the balance of structural and signaling lipids to fuel cancer pathogenicity.

Novel mutations in AGPS (alkylglycerone-phosphate synthase) cause rhizomelic chondrodysplasia punctata (RCDP) type 3.
Title: Functional characterization of novel mutations in GNPAT and AGPS, causing rhizomelic chondrodysplasia punctata (RCDP) types 2 and 3.

The following AGPS gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the AGPS cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu17928	NM_003659.4 Latest version!	Homo sapiens alkylglycerone phosphate synthase (AGPS), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
OHu61936	XM_011512041.2 Latest version!	Homo sapiens alkylglycerone phosphate synthase (AGPS), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$307.30 $439.00
OHu61936	XM_011512042.1 Latest version!	Homo sapiens alkylglycerone phosphate synthase (AGPS), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$307.30 $439.00
OHu61937	XM_011512043.2 Latest version!	Homo sapiens alkylglycerone phosphate synthase (AGPS), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$223.30 $319.00
View Old Accession Versions >>
OHu17928	NM_003659.3	Homo sapiens alkylglycerone phosphate synthase (AGPS), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
Hide Old Accession Versions >>

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***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

AGPS ( NM_003659.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_003650.1 Homo sapiens alkylglycerone phosphate synthase (AGPS), mRNA.

Price & Availability↑

CloneID	OHu17928
Clone ID Related Accession (Same CDS sequence)	NM_003659.4 , NM_003659.3
Accession Version	NM_003659.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1977bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-26
Organism	Homo sapiens(human)
Product	alkyldihydroxyacetonephosphate synthase, peroxisomal precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK314259.1, AC073834.6 and AA832354.1. This sequence is a reference standard in the RefSeqGene project. On Nov 23, 2018 this sequence version replaced NM_003659.3. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The extent of this transcript is supported by transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803614.69648.1, SRR1660807.66305.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGCGGAGG CGGCGGCTGC AGCGGGTGGG ACTGGCTTGG GCGCGGGCGC GAGCTACGGG 
TCTGCAGCGG ACCGGGACCG GGACCCGGAC CCGGACCGCG CCGGGCGGAG GCTGCGGGTT 
CTCTCTGGCC ATCTGCTGGG CCGGCCCCGG GAGGCTCTGA GTACCAATGA GTGCAAAGCG 
CGGAGAGCCG CGTCGGCGGC CACGGCAGCG CCCACGGCCA CTCCCGCCGC GCAGGAGTCG 
GGCACCATCC CAAAGAAGCG GCAAGAAGTT ATGAAATGGA ATGGATGGGG ATATAATGAT 
TCTAAATTCA TCTTCAATAA GAAGGGCCAA ATTGAATTGA CTGGGAAAAG GTACCCTCTT 
AGTGGCATGG GTTTACCAAC ATTTAAAGAA TGGATCCAAA ATACCCTTGG AGTAAATGTG 
GAGCATAAAA CTACCTCTAA AGCATCCTTA AATCCTAGTG ATACACCTCC TTCTGTTGTA 
AATGAAGATT TTCTTCATGA CCTTAAAGAA ACTAATATTT CATATTCACA AGAGGCAGAT 
GATCGAGTAT TTAGAGCTCA TGGTCATTGT CTTCATGAGA TATTTTTGCT CAGGGAAGGA 
ATGTTTGAGC GAATTCCTGA TATAGTTTTA TGGCCAACAT GCCATGATGA TGTAGTTAAG 
ATTGTGAATC TAGCTTGCAA ATATAATCTT TGTATCATAC CAATTGGTGG AGGAACAAGT 
GTTTCATATG GCCTGATGTG TCCTGCAGAT GAGACAAGAA CAATTATTTC TTTGGACACT 
TCACAAATGA ATCGAATTCT CTGGGTTGAT GAGAACAATT TGACAGCTCA TGTAGAGGCT 
GGCATAACAG GACAAGAGTT GGAAAGACAG CTTAAAGAAA GTGGTTATTG TACAGGTCAT 
GAACCAGATT CCCTGGAGTT CAGTACTGTA GGAGGATGGG TATCTACTCG CGCATCAGGC 
ATGAAGAAGA ATATCTATGG CAATATCGAG GACCTGGTGG TTCATATAAA AATGGTAACA 
CCTAGAGGTA TAATAGAAAA AAGCTGTCAA GGACCTCGTA TGTCAACAGG CCCTGATATC 
CATCACTTCA TCATGGGATC TGAAGGAACT CTTGGTGTAA TAACAGAAGC TACAATAAAA 
ATCAGACCAG TCCCTGAATA CCAAAAGTAT GGCTCAGTAG CTTTCCCTAA TTTTGAACAA 
GGAGTAGCCT GTTTAAGAGA AATTGCAAAA CAGAGATGTG CTCCGGCATC TATTCGCCTC 
ATGGACAACA AGCAGTTTCA GTTTGGTCAT GCTCTTAAAC CTCAGGTTTC CTCTATTTTT 
ACATCATTTT TGGACGGATT AAAAAAGTTT TATATTACAA AGTTTAAAGG ATTTGACCCA 
AATCAGCTAA GTGTAGCCAC ATTACTGTTT GAGGGGGATC GTGAGAAGGT TCTTCAACAT 
GAAAAACAAG TGTATGATAT TGCTGCAAAA TTTGGTGGGT TGGCAGCTGG AGAAGATAAT 
GGACAGAGAG GTTATTTGCT GACCTATGTT ATTGCATACA TTCGAGACTT GGCTTTGGAA 
TACTATGTAT TAGGAGAATC TTTTGAGACT TCTGCTCCTT GGGACAGGGT GGTAGATCTC 
TGTAGAAATG TAAAAGAAAG AATAACAAGG GAATGCAAAG AGAAGGGTGT TCAGTTTGCT 
CCTTTTTCTA CATGCAGGGT GACGCAGACT TACGATGCAG GTGCTTGTAT CTACTTCTAT 
TTTGCCTTTA ACTACAGGGG AATTAGTGAC CCACTGACCG TATTTGAACA AACTGAGGCA 
GCTGCTAGAG AAGAAATCCT TGCTAATGGA GGGAGCCTGT CACATCACCA TGGAGTGGGC 
AAGTTACGGA AGCAATGGCT AAAGGAAAGT ATCTCTGATG TCGGCTTTGG GATGCTGAAG 
TCTGTCAAGG AATATGTGGA CCCCAATAAC ATCTTTGGAA ACAGAAACCT TTTATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_003650.1
CDS	18..1994
Translation	MAEAAAAAGGTGLGAGASYGSAADRDRDPDPDRAGRRLRVLSGHLLGRPREALSTNECKARRAASAATAAPTATPAAQESGTIPKKRQEVMKWNGWGYNDSKFIFNKKGQIELTGKRYPLSGMGLPTFKEWIQNTLGVNVEHKTTSKASLNPSDTPPSVVNEDFLHDLKETNISYSQEADDRVFRAHGHCLHEIFLLREGMFERIPDIVLWPTCHDDVVKIVNLACKYNLCIIPIGGGTSVSYGLMCPADETRTIISLDTSQMNRILWVDENNLTAHVEAGITGQELERQLKESGYCTGHEPDSLEFSTVGGWVSTRASGMKKNIYGNIEDLVVHIKMVTPRGIIEKSCQGPRMSTGPDIHHFIMGSEGTLGVITEATIKIRPVPEYQKYGSVAFPNFEQGVACLREIAKQRCAPASIRLMDNKQFQFGHALKPQVSSIFTSFLDGLKKFYITKFKGFDPNQLSVATLLFEGDREKVLQHEKQVYDIAAKFGGLAAGEDNGQRGYLLTYVIAYIRDLALEYYVLGESFETSAPWDRVVDLCRNVKERITRECKEKGVQFAPFSTCRVTQTYDAGACIYFYFAFNYRGISDPLTVFEQTEAAAREEILANGGSLSHHHGVGKLRKQWLKESISDVGFGMLKSVKEYVDPNNIFGNRNLL

Target ORF information:

RefSeq Version	NM_003659.4
Organism	Homo sapiens(human)
Definition	Homo sapiens alkylglycerone phosphate synthase (AGPS), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_003659.4

ORF Insert Sequence:

ATGGCGGAGG CGGCGGCTGC AGCGGGTGGG ACTGGCTTGG GCGCGGGCGC GAGCTACGGG 
TCTGCAGCGG ACCGGGACCG GGACCCGGAC CCGGACCGCG CCGGGCGGAG GCTGCGGGTT 
CTCTCTGGCC ATCTGCTGGG CCGGCCCCGG GAGGCTCTGA GTACCAATGA GTGCAAAGCG 
CGGAGAGCCG CGTCGGCGGC CACGGCAGCG CCCACGGCCA CTCCCGCCGC GCAGGAGTCG 
GGCACCATCC CAAAGAAGCG GCAAGAAGTT ATGAAATGGA ATGGATGGGG ATATAATGAT 
TCTAAATTCA TCTTCAATAA GAAGGGCCAA ATTGAATTGA CTGGGAAAAG GTACCCTCTT 
AGTGGCATGG GTTTACCAAC ATTTAAAGAA TGGATCCAAA ATACCCTTGG AGTAAATGTG 
GAGCATAAAA CTACCTCTAA AGCATCCTTA AATCCTAGTG ATACACCTCC TTCTGTTGTA 
AATGAAGATT TTCTTCATGA CCTTAAAGAA ACTAATATTT CATATTCACA AGAGGCAGAT 
GATCGAGTAT TTAGAGCTCA TGGTCATTGT CTTCATGAGA TATTTTTGCT CAGGGAAGGA 
ATGTTTGAGC GAATTCCTGA TATAGTTTTA TGGCCAACAT GCCATGATGA TGTAGTTAAG 
ATTGTGAATC TAGCTTGCAA ATATAATCTT TGTATCATAC CAATTGGTGG AGGAACAAGT 
GTTTCATATG GCCTGATGTG TCCTGCAGAT GAGACAAGAA CAATTATTTC TTTGGACACT 
TCACAAATGA ATCGAATTCT CTGGGTTGAT GAGAACAATT TGACAGCTCA TGTAGAGGCT 
GGCATAACAG GACAAGAGTT GGAAAGACAG CTTAAAGAAA GTGGTTATTG TACAGGTCAT 
GAACCAGATT CCCTGGAGTT CAGTACTGTA GGAGGATGGG TATCTACTCG CGCATCAGGC 
ATGAAGAAGA ATATCTATGG CAATATCGAG GACCTGGTGG TTCATATAAA AATGGTAACA 
CCTAGAGGTA TAATAGAAAA AAGCTGTCAA GGACCTCGTA TGTCAACAGG CCCTGATATC 
CATCACTTCA TCATGGGATC TGAAGGAACT CTTGGTGTAA TAACAGAAGC TACAATAAAA 
ATCAGACCAG TCCCTGAATA CCAAAAGTAT GGCTCAGTAG CTTTCCCTAA TTTTGAACAA 
GGAGTAGCCT GTTTAAGAGA AATTGCAAAA CAGAGATGTG CTCCGGCATC TATTCGCCTC 
ATGGACAACA AGCAGTTTCA GTTTGGTCAT GCTCTTAAAC CTCAGGTTTC CTCTATTTTT 
ACATCATTTT TGGACGGATT AAAAAAGTTT TATATTACAA AGTTTAAAGG ATTTGACCCA 
AATCAGCTAA GTGTAGCCAC ATTACTGTTT GAGGGGGATC GTGAGAAGGT TCTTCAACAT 
GAAAAACAAG TGTATGATAT TGCTGCAAAA TTTGGTGGGT TGGCAGCTGG AGAAGATAAT 
GGACAGAGAG GTTATTTGCT GACCTATGTT ATTGCATACA TTCGAGACTT GGCTTTGGAA 
TACTATGTAT TAGGAGAATC TTTTGAGACT TCTGCTCCTT GGGACAGGGT GGTAGATCTC 
TGTAGAAATG TAAAAGAAAG AATAACAAGG GAATGCAAAG AGAAGGGTGT TCAGTTTGCT 
CCTTTTTCTA CATGCAGGGT GACGCAGACT TACGATGCAG GTGCTTGTAT CTACTTCTAT 
TTTGCCTTTA ACTACAGGGG AATTAGTGAC CCACTGACCG TATTTGAACA AACTGAGGCA 
GCTGCTAGAG AAGAAATCCT TGCTAATGGA GGGAGCCTGT CACATCACCA TGGAGTGGGC 
AAGTTACGGA AGCAATGGCT AAAGGAAAGT ATCTCTGATG TCGGCTTTGG GATGCTGAAG 
TCTGTCAAGG AATATGTGGA CCCCAATAAC ATCTTTGGAA ACAGAAACCT TTTATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

AGPS ( NM_003659.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_003650.1 Homo sapiens alkylglycerone phosphate synthase (AGPS), mRNA.

Price & Availability↑

CloneID	OHu17928
Clone ID Related Accession (Same CDS sequence)	NM_003659.4 , NM_003659.3
Accession Version	NM_003659.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1977bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-01
Organism	Homo sapiens(human)
Product	alkyldihydroxyacetonephosphate synthase, peroxisomal precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DC402978.1, AK314259.1, AC073834.6 and AA832354.1. This sequence is a reference standard in the RefSeqGene project. On Jun 6, 2008 this sequence version replaced NM_003659.2. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The extent of this transcript is supported by transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660807.66305.1, SRR1660803.91434.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCGGAGG CGGCGGCTGC AGCGGGTGGG ACTGGCTTGG GCGCGGGCGC GAGCTACGGG 
TCTGCAGCGG ACCGGGACCG GGACCCGGAC CCGGACCGCG CCGGGCGGAG GCTGCGGGTT 
CTCTCTGGCC ATCTGCTGGG CCGGCCCCGG GAGGCTCTGA GTACCAATGA GTGCAAAGCG 
CGGAGAGCCG CGTCGGCGGC CACGGCAGCG CCCACGGCCA CTCCCGCCGC GCAGGAGTCG 
GGCACCATCC CAAAGAAGCG GCAAGAAGTT ATGAAATGGA ATGGATGGGG ATATAATGAT 
TCTAAATTCA TCTTCAATAA GAAGGGCCAA ATTGAATTGA CTGGGAAAAG GTACCCTCTT 
AGTGGCATGG GTTTACCAAC ATTTAAAGAA TGGATCCAAA ATACCCTTGG AGTAAATGTG 
GAGCATAAAA CTACCTCTAA AGCATCCTTA AATCCTAGTG ATACACCTCC TTCTGTTGTA 
AATGAAGATT TTCTTCATGA CCTTAAAGAA ACTAATATTT CATATTCACA AGAGGCAGAT 
GATCGAGTAT TTAGAGCTCA TGGTCATTGT CTTCATGAGA TATTTTTGCT CAGGGAAGGA 
ATGTTTGAGC GAATTCCTGA TATAGTTTTA TGGCCAACAT GCCATGATGA TGTAGTTAAG 
ATTGTGAATC TAGCTTGCAA ATATAATCTT TGTATCATAC CAATTGGTGG AGGAACAAGT 
GTTTCATATG GCCTGATGTG TCCTGCAGAT GAGACAAGAA CAATTATTTC TTTGGACACT 
TCACAAATGA ATCGAATTCT CTGGGTTGAT GAGAACAATT TGACAGCTCA TGTAGAGGCT 
GGCATAACAG GACAAGAGTT GGAAAGACAG CTTAAAGAAA GTGGTTATTG TACAGGTCAT 
GAACCAGATT CCCTGGAGTT CAGTACTGTA GGAGGATGGG TATCTACTCG CGCATCAGGC 
ATGAAGAAGA ATATCTATGG CAATATCGAG GACCTGGTGG TTCATATAAA AATGGTAACA 
CCTAGAGGTA TAATAGAAAA AAGCTGTCAA GGACCTCGTA TGTCAACAGG CCCTGATATC 
CATCACTTCA TCATGGGATC TGAAGGAACT CTTGGTGTAA TAACAGAAGC TACAATAAAA 
ATCAGACCAG TCCCTGAATA CCAAAAGTAT GGCTCAGTAG CTTTCCCTAA TTTTGAACAA 
GGAGTAGCCT GTTTAAGAGA AATTGCAAAA CAGAGATGTG CTCCGGCATC TATTCGCCTC 
ATGGACAACA AGCAGTTTCA GTTTGGTCAT GCTCTTAAAC CTCAGGTTTC CTCTATTTTT 
ACATCATTTT TGGACGGATT AAAAAAGTTT TATATTACAA AGTTTAAAGG ATTTGACCCA 
AATCAGCTAA GTGTAGCCAC ATTACTGTTT GAGGGGGATC GTGAGAAGGT TCTTCAACAT 
GAAAAACAAG TGTATGATAT TGCTGCAAAA TTTGGTGGGT TGGCAGCTGG AGAAGATAAT 
GGACAGAGAG GTTATTTGCT GACCTATGTT ATTGCATACA TTCGAGACTT GGCTTTGGAA 
TACTATGTAT TAGGAGAATC TTTTGAGACT TCTGCTCCTT GGGACAGGGT GGTAGATCTC 
TGTAGAAATG TAAAAGAAAG AATAACAAGG GAATGCAAAG AGAAGGGTGT TCAGTTTGCT 
CCTTTTTCTA CATGCAGGGT GACGCAGACT TACGATGCAG GTGCTTGTAT CTACTTCTAT 
TTTGCCTTTA ACTACAGGGG AATTAGTGAC CCACTGACCG TATTTGAACA AACTGAGGCA 
GCTGCTAGAG AAGAAATCCT TGCTAATGGA GGGAGCCTGT CACATCACCA TGGAGTGGGC 
AAGTTACGGA AGCAATGGCT AAAGGAAAGT ATCTCTGATG TCGGCTTTGG GATGCTGAAG 
TCTGTCAAGG AATATGTGGA CCCCAATAAC ATCTTTGGAA ACAGAAACCT TTTATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_003650.1
CDS	48..2024
Translation	MAEAAAAAGGTGLGAGASYGSAADRDRDPDPDRAGRRLRVLSGHLLGRPREALSTNECKARRAASAATAAPTATPAAQESGTIPKKRQEVMKWNGWGYNDSKFIFNKKGQIELTGKRYPLSGMGLPTFKEWIQNTLGVNVEHKTTSKASLNPSDTPPSVVNEDFLHDLKETNISYSQEADDRVFRAHGHCLHEIFLLREGMFERIPDIVLWPTCHDDVVKIVNLACKYNLCIIPIGGGTSVSYGLMCPADETRTIISLDTSQMNRILWVDENNLTAHVEAGITGQELERQLKESGYCTGHEPDSLEFSTVGGWVSTRASGMKKNIYGNIEDLVVHIKMVTPRGIIEKSCQGPRMSTGPDIHHFIMGSEGTLGVITEATIKIRPVPEYQKYGSVAFPNFEQGVACLREIAKQRCAPASIRLMDNKQFQFGHALKPQVSSIFTSFLDGLKKFYITKFKGFDPNQLSVATLLFEGDREKVLQHEKQVYDIAAKFGGLAAGEDNGQRGYLLTYVIAYIRDLALEYYVLGESFETSAPWDRVVDLCRNVKERITRECKEKGVQFAPFSTCRVTQTYDAGACIYFYFAFNYRGISDPLTVFEQTEAAAREEILANGGSLSHHHGVGKLRKQWLKESISDVGFGMLKSVKEYVDPNNIFGNRNLL

Target ORF information:

RefSeq Version	NM_003659.3
Organism	Homo sapiens(human)
Definition	Homo sapiens alkylglycerone phosphate synthase (AGPS), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_003659.3

ORF Insert Sequence:

ATGGCGGAGG CGGCGGCTGC AGCGGGTGGG ACTGGCTTGG GCGCGGGCGC GAGCTACGGG 
TCTGCAGCGG ACCGGGACCG GGACCCGGAC CCGGACCGCG CCGGGCGGAG GCTGCGGGTT 
CTCTCTGGCC ATCTGCTGGG CCGGCCCCGG GAGGCTCTGA GTACCAATGA GTGCAAAGCG 
CGGAGAGCCG CGTCGGCGGC CACGGCAGCG CCCACGGCCA CTCCCGCCGC GCAGGAGTCG 
GGCACCATCC CAAAGAAGCG GCAAGAAGTT ATGAAATGGA ATGGATGGGG ATATAATGAT 
TCTAAATTCA TCTTCAATAA GAAGGGCCAA ATTGAATTGA CTGGGAAAAG GTACCCTCTT 
AGTGGCATGG GTTTACCAAC ATTTAAAGAA TGGATCCAAA ATACCCTTGG AGTAAATGTG 
GAGCATAAAA CTACCTCTAA AGCATCCTTA AATCCTAGTG ATACACCTCC TTCTGTTGTA 
AATGAAGATT TTCTTCATGA CCTTAAAGAA ACTAATATTT CATATTCACA AGAGGCAGAT 
GATCGAGTAT TTAGAGCTCA TGGTCATTGT CTTCATGAGA TATTTTTGCT CAGGGAAGGA 
ATGTTTGAGC GAATTCCTGA TATAGTTTTA TGGCCAACAT GCCATGATGA TGTAGTTAAG 
ATTGTGAATC TAGCTTGCAA ATATAATCTT TGTATCATAC CAATTGGTGG AGGAACAAGT 
GTTTCATATG GCCTGATGTG TCCTGCAGAT GAGACAAGAA CAATTATTTC TTTGGACACT 
TCACAAATGA ATCGAATTCT CTGGGTTGAT GAGAACAATT TGACAGCTCA TGTAGAGGCT 
GGCATAACAG GACAAGAGTT GGAAAGACAG CTTAAAGAAA GTGGTTATTG TACAGGTCAT 
GAACCAGATT CCCTGGAGTT CAGTACTGTA GGAGGATGGG TATCTACTCG CGCATCAGGC 
ATGAAGAAGA ATATCTATGG CAATATCGAG GACCTGGTGG TTCATATAAA AATGGTAACA 
CCTAGAGGTA TAATAGAAAA AAGCTGTCAA GGACCTCGTA TGTCAACAGG CCCTGATATC 
CATCACTTCA TCATGGGATC TGAAGGAACT CTTGGTGTAA TAACAGAAGC TACAATAAAA 
ATCAGACCAG TCCCTGAATA CCAAAAGTAT GGCTCAGTAG CTTTCCCTAA TTTTGAACAA 
GGAGTAGCCT GTTTAAGAGA AATTGCAAAA CAGAGATGTG CTCCGGCATC TATTCGCCTC 
ATGGACAACA AGCAGTTTCA GTTTGGTCAT GCTCTTAAAC CTCAGGTTTC CTCTATTTTT 
ACATCATTTT TGGACGGATT AAAAAAGTTT TATATTACAA AGTTTAAAGG ATTTGACCCA 
AATCAGCTAA GTGTAGCCAC ATTACTGTTT GAGGGGGATC GTGAGAAGGT TCTTCAACAT 
GAAAAACAAG TGTATGATAT TGCTGCAAAA TTTGGTGGGT TGGCAGCTGG AGAAGATAAT 
GGACAGAGAG GTTATTTGCT GACCTATGTT ATTGCATACA TTCGAGACTT GGCTTTGGAA 
TACTATGTAT TAGGAGAATC TTTTGAGACT TCTGCTCCTT GGGACAGGGT GGTAGATCTC 
TGTAGAAATG TAAAAGAAAG AATAACAAGG GAATGCAAAG AGAAGGGTGT TCAGTTTGCT 
CCTTTTTCTA CATGCAGGGT GACGCAGACT TACGATGCAG GTGCTTGTAT CTACTTCTAT 
TTTGCCTTTA ACTACAGGGG AATTAGTGAC CCACTGACCG TATTTGAACA AACTGAGGCA 
GCTGCTAGAG AAGAAATCCT TGCTAATGGA GGGAGCCTGT CACATCACCA TGGAGTGGGC 
AAGTTACGGA AGCAATGGCT AAAGGAAAGT ATCTCTGATG TCGGCTTTGG GATGCTGAAG 
TCTGTCAAGG AATATGTGGA CCCCAATAAC ATCTTTGGAA ACAGAAACCT TTTATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

AGPS ( XM_011512042.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_011510344.1 Homo sapiens alkylglycerone phosphate synthase (AGPS), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu61936
Clone ID Related Accession (Same CDS sequence)	XM_011512042.1 , XM_011512041.2
Accession Version	XM_011512042.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1707bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	alkyldihydroxyacetonephosphate synthase, peroxisomal isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000002.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAAATGGA ATGGATGGGG ATATAATGAT TCTAAATTCA TCTTCAATAA GAAGGGCCAA 
ATTGAATTGA CTGGGAAAAG GTACCCTCTT AGTGGCATGG GTTTACCAAC ATTTAAAGAA 
TGGATCCAAA ATACCCTTGG AGTAAATGTG GAGCATAAAA CTACCTCTAA AGCATCCTTA 
AATCCTAGTG ATACACCTCC TTCTGTTGTA AATGAAGATT TTCTTCATGA CCTTAAAGAA 
ACTAATATTT CATATTCACA AGAGGCAGAT GATCGAGTAT TTAGAGCTCA TGGTCATTGT 
CTTCATGAGA TATTTTTGCT CAGGGAAGGA ATGTTTGAGC GAATTCCTGA TATAGTTTTA 
TGGCCAACAT GCCATGATGA TGTAGTTAAG ATTGTGAATC TAGCTTGCAA ATATAATCTT 
TGTATCATAC CAATTGGTGG AGGAACAAGT GTTTCATATG GCCTGATGTG TCCTGCAGAT 
GAGACAAGAA CAATTATTTC TTTGGACACT TCACAAATGA ATCGAATTCT CTGGGTTGAT 
GAGAACAATT TGACAGCTCA TGTAGAGGCT GGCATAACAG GACAAGAGTT GGAAAGACAG 
CTTAAAGAAA GTGGTTATTG TACAGGTCAT GAACCAGATT CCCTGGAGTT CAGTACTGTA 
GGAGGATGGG TATCTACTCG CGCATCAGGC ATGAAGAAGA ATATCTATGG CAATATCGAG 
GACCTGGTGG TTCATATAAA AATGGTAACA CCTAGAGGTA TAATAGAAAA AAGCTGTCAA 
GGACCTCGTA TGTCAACAGG CCCTGATATC CATCACTTCA TCATGGGATC TGAAGGAACT 
CTTGGTGTAA TAACAGAAGC TACAATAAAA ATCAGACCAG TCCCTGAATA CCAAAAGTAT 
GGCTCAGTAG CTTTCCCTAA TTTTGAACAA GGAGTAGCCT GTTTAAGAGA AATTGCAAAA 
CAGAGATGTG CTCCGGCATC TATTCGCCTC ATGGACAACA AGCAGTTTCA GTTTGGTCAT 
GCTCTTAAAC CTCAGGTTTC CTCTATTTTT ACATCATTTT TGGACGGATT AAAAAAGTTT 
TATATTACAA AGTTTAAAGG ATTTGACCCA AATCAGCTAA GTGTAGCCAC ATTACTGTTT 
GAGGGGGATC GTGAGAAGGT TCTTCAACAT GAAAAACAAG TGTATGATAT TGCTGCAAAA 
TTTGGTGGGT TGGCAGCTGG AGAAGATAAT GGACAGAGAG GTTATTTGCT GACCTATGTT 
ATTGCATACA TTCGAGACTT GGCTTTGGAA TACTATGTAT TAGGAGAATC TTTTGAGACT 
TCTGCTCCTT GGGACAGGGT GGTAGATCTC TGTAGAAATG TAAAAGAAAG AATAACAAGG 
GAATGCAAAG AGAAGGGTGT TCAGTTTGCT CCTTTTTCTA CATGCAGGGT GACGCAGACT 
TACGATGCAG GTGCTTGTAT CTACTTCTAT TTTGCCTTTA ACTACAGGGG AATTAGTGAC 
CCACTGACCG TATTTGAACA AACTGAGGCA GCTGCTAGAG AAGAAATCCT TGCTAATGGA 
GGGAGCCTGT CACATCACCA TGGAGTGGGC AAGTTACGGA AGCAATGGCT AAAGGAAAGT 
ATCTCTGATG TCGGCTTTGG GATGCTGAAG TCTGTCAAGG AATATGTGGA CCCCAATAAC 
ATCTTTGGAA ACAGAAACCT TTTATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011510344.1
CDS	267..1973
Translation	MKWNGWGYNDSKFIFNKKGQIELTGKRYPLSGMGLPTFKEWIQNTLGVNVEHKTTSKASLNPSDTPPSVVNEDFLHDLKETNISYSQEADDRVFRAHGHCLHEIFLLREGMFERIPDIVLWPTCHDDVVKIVNLACKYNLCIIPIGGGTSVSYGLMCPADETRTIISLDTSQMNRILWVDENNLTAHVEAGITGQELERQLKESGYCTGHEPDSLEFSTVGGWVSTRASGMKKNIYGNIEDLVVHIKMVTPRGIIEKSCQGPRMSTGPDIHHFIMGSEGTLGVITEATIKIRPVPEYQKYGSVAFPNFEQGVACLREIAKQRCAPASIRLMDNKQFQFGHALKPQVSSIFTSFLDGLKKFYITKFKGFDPNQLSVATLLFEGDREKVLQHEKQVYDIAAKFGGLAAGEDNGQRGYLLTYVIAYIRDLALEYYVLGESFETSAPWDRVVDLCRNVKERITRECKEKGVQFAPFSTCRVTQTYDAGACIYFYFAFNYRGISDPLTVFEQTEAAAREEILANGGSLSHHHGVGKLRKQWLKESISDVGFGMLKSVKEYVDPNNIFGNRNLL

Target ORF information:

RefSeq Version	XM_011512042.1
Organism	Homo sapiens(human)
Definition	Homo sapiens alkylglycerone phosphate synthase (AGPS), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011512042.1

ORF Insert Sequence:

ATGAAATGGA ATGGATGGGG ATATAATGAT TCTAAATTCA TCTTCAATAA GAAGGGCCAA 
ATTGAATTGA CTGGGAAAAG GTACCCTCTT AGTGGCATGG GTTTACCAAC ATTTAAAGAA 
TGGATCCAAA ATACCCTTGG AGTAAATGTG GAGCATAAAA CTACCTCTAA AGCATCCTTA 
AATCCTAGTG ATACACCTCC TTCTGTTGTA AATGAAGATT TTCTTCATGA CCTTAAAGAA 
ACTAATATTT CATATTCACA AGAGGCAGAT GATCGAGTAT TTAGAGCTCA TGGTCATTGT 
CTTCATGAGA TATTTTTGCT CAGGGAAGGA ATGTTTGAGC GAATTCCTGA TATAGTTTTA 
TGGCCAACAT GCCATGATGA TGTAGTTAAG ATTGTGAATC TAGCTTGCAA ATATAATCTT 
TGTATCATAC CAATTGGTGG AGGAACAAGT GTTTCATATG GCCTGATGTG TCCTGCAGAT 
GAGACAAGAA CAATTATTTC TTTGGACACT TCACAAATGA ATCGAATTCT CTGGGTTGAT 
GAGAACAATT TGACAGCTCA TGTAGAGGCT GGCATAACAG GACAAGAGTT GGAAAGACAG 
CTTAAAGAAA GTGGTTATTG TACAGGTCAT GAACCAGATT CCCTGGAGTT CAGTACTGTA 
GGAGGATGGG TATCTACTCG CGCATCAGGC ATGAAGAAGA ATATCTATGG CAATATCGAG 
GACCTGGTGG TTCATATAAA AATGGTAACA CCTAGAGGTA TAATAGAAAA AAGCTGTCAA 
GGACCTCGTA TGTCAACAGG CCCTGATATC CATCACTTCA TCATGGGATC TGAAGGAACT 
CTTGGTGTAA TAACAGAAGC TACAATAAAA ATCAGACCAG TCCCTGAATA CCAAAAGTAT 
GGCTCAGTAG CTTTCCCTAA TTTTGAACAA GGAGTAGCCT GTTTAAGAGA AATTGCAAAA 
CAGAGATGTG CTCCGGCATC TATTCGCCTC ATGGACAACA AGCAGTTTCA GTTTGGTCAT 
GCTCTTAAAC CTCAGGTTTC CTCTATTTTT ACATCATTTT TGGACGGATT AAAAAAGTTT 
TATATTACAA AGTTTAAAGG ATTTGACCCA AATCAGCTAA GTGTAGCCAC ATTACTGTTT 
GAGGGGGATC GTGAGAAGGT TCTTCAACAT GAAAAACAAG TGTATGATAT TGCTGCAAAA 
TTTGGTGGGT TGGCAGCTGG AGAAGATAAT GGACAGAGAG GTTATTTGCT GACCTATGTT 
ATTGCATACA TTCGAGACTT GGCTTTGGAA TACTATGTAT TAGGAGAATC TTTTGAGACT 
TCTGCTCCTT GGGACAGGGT GGTAGATCTC TGTAGAAATG TAAAAGAAAG AATAACAAGG 
GAATGCAAAG AGAAGGGTGT TCAGTTTGCT CCTTTTTCTA CATGCAGGGT GACGCAGACT 
TACGATGCAG GTGCTTGTAT CTACTTCTAT TTTGCCTTTA ACTACAGGGG AATTAGTGAC 
CCACTGACCG TATTTGAACA AACTGAGGCA GCTGCTAGAG AAGAAATCCT TGCTAATGGA 
GGGAGCCTGT CACATCACCA TGGAGTGGGC AAGTTACGGA AGCAATGGCT AAAGGAAAGT 
ATCTCTGATG TCGGCTTTGG GATGCTGAAG TCTGTCAAGG AATATGTGGA CCCCAATAAC 
ATCTTTGGAA ACAGAAACCT TTTATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

AGPS ( XM_011512041.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011510343.1 Homo sapiens alkylglycerone phosphate synthase (AGPS), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu61936
Clone ID Related Accession (Same CDS sequence)	XM_011512042.1 , XM_011512041.2
Accession Version	XM_011512041.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1707bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	alkyldihydroxyacetonephosphate synthase, peroxisomal isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000002.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011512041.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAAATGGA ATGGATGGGG ATATAATGAT TCTAAATTCA TCTTCAATAA GAAGGGCCAA 
ATTGAATTGA CTGGGAAAAG GTACCCTCTT AGTGGCATGG GTTTACCAAC ATTTAAAGAA 
TGGATCCAAA ATACCCTTGG AGTAAATGTG GAGCATAAAA CTACCTCTAA AGCATCCTTA 
AATCCTAGTG ATACACCTCC TTCTGTTGTA AATGAAGATT TTCTTCATGA CCTTAAAGAA 
ACTAATATTT CATATTCACA AGAGGCAGAT GATCGAGTAT TTAGAGCTCA TGGTCATTGT 
CTTCATGAGA TATTTTTGCT CAGGGAAGGA ATGTTTGAGC GAATTCCTGA TATAGTTTTA 
TGGCCAACAT GCCATGATGA TGTAGTTAAG ATTGTGAATC TAGCTTGCAA ATATAATCTT 
TGTATCATAC CAATTGGTGG AGGAACAAGT GTTTCATATG GCCTGATGTG TCCTGCAGAT 
GAGACAAGAA CAATTATTTC TTTGGACACT TCACAAATGA ATCGAATTCT CTGGGTTGAT 
GAGAACAATT TGACAGCTCA TGTAGAGGCT GGCATAACAG GACAAGAGTT GGAAAGACAG 
CTTAAAGAAA GTGGTTATTG TACAGGTCAT GAACCAGATT CCCTGGAGTT CAGTACTGTA 
GGAGGATGGG TATCTACTCG CGCATCAGGC ATGAAGAAGA ATATCTATGG CAATATCGAG 
GACCTGGTGG TTCATATAAA AATGGTAACA CCTAGAGGTA TAATAGAAAA AAGCTGTCAA 
GGACCTCGTA TGTCAACAGG CCCTGATATC CATCACTTCA TCATGGGATC TGAAGGAACT 
CTTGGTGTAA TAACAGAAGC TACAATAAAA ATCAGACCAG TCCCTGAATA CCAAAAGTAT 
GGCTCAGTAG CTTTCCCTAA TTTTGAACAA GGAGTAGCCT GTTTAAGAGA AATTGCAAAA 
CAGAGATGTG CTCCGGCATC TATTCGCCTC ATGGACAACA AGCAGTTTCA GTTTGGTCAT 
GCTCTTAAAC CTCAGGTTTC CTCTATTTTT ACATCATTTT TGGACGGATT AAAAAAGTTT 
TATATTACAA AGTTTAAAGG ATTTGACCCA AATCAGCTAA GTGTAGCCAC ATTACTGTTT 
GAGGGGGATC GTGAGAAGGT TCTTCAACAT GAAAAACAAG TGTATGATAT TGCTGCAAAA 
TTTGGTGGGT TGGCAGCTGG AGAAGATAAT GGACAGAGAG GTTATTTGCT GACCTATGTT 
ATTGCATACA TTCGAGACTT GGCTTTGGAA TACTATGTAT TAGGAGAATC TTTTGAGACT 
TCTGCTCCTT GGGACAGGGT GGTAGATCTC TGTAGAAATG TAAAAGAAAG AATAACAAGG 
GAATGCAAAG AGAAGGGTGT TCAGTTTGCT CCTTTTTCTA CATGCAGGGT GACGCAGACT 
TACGATGCAG GTGCTTGTAT CTACTTCTAT TTTGCCTTTA ACTACAGGGG AATTAGTGAC 
CCACTGACCG TATTTGAACA AACTGAGGCA GCTGCTAGAG AAGAAATCCT TGCTAATGGA 
GGGAGCCTGT CACATCACCA TGGAGTGGGC AAGTTACGGA AGCAATGGCT AAAGGAAAGT 
ATCTCTGATG TCGGCTTTGG GATGCTGAAG TCTGTCAAGG AATATGTGGA CCCCAATAAC 
ATCTTTGGAA ACAGAAACCT TTTATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011510343.1
CDS	100..1806
Translation	MKWNGWGYNDSKFIFNKKGQIELTGKRYPLSGMGLPTFKEWIQNTLGVNVEHKTTSKASLNPSDTPPSVVNEDFLHDLKETNISYSQEADDRVFRAHGHCLHEIFLLREGMFERIPDIVLWPTCHDDVVKIVNLACKYNLCIIPIGGGTSVSYGLMCPADETRTIISLDTSQMNRILWVDENNLTAHVEAGITGQELERQLKESGYCTGHEPDSLEFSTVGGWVSTRASGMKKNIYGNIEDLVVHIKMVTPRGIIEKSCQGPRMSTGPDIHHFIMGSEGTLGVITEATIKIRPVPEYQKYGSVAFPNFEQGVACLREIAKQRCAPASIRLMDNKQFQFGHALKPQVSSIFTSFLDGLKKFYITKFKGFDPNQLSVATLLFEGDREKVLQHEKQVYDIAAKFGGLAAGEDNGQRGYLLTYVIAYIRDLALEYYVLGESFETSAPWDRVVDLCRNVKERITRECKEKGVQFAPFSTCRVTQTYDAGACIYFYFAFNYRGISDPLTVFEQTEAAAREEILANGGSLSHHHGVGKLRKQWLKESISDVGFGMLKSVKEYVDPNNIFGNRNLL

Target ORF information:

RefSeq Version	XM_011512041.2
Organism	Homo sapiens(human)
Definition	Homo sapiens alkylglycerone phosphate synthase (AGPS), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011512041.2

ORF Insert Sequence:

ATGAAATGGA ATGGATGGGG ATATAATGAT TCTAAATTCA TCTTCAATAA GAAGGGCCAA 
ATTGAATTGA CTGGGAAAAG GTACCCTCTT AGTGGCATGG GTTTACCAAC ATTTAAAGAA 
TGGATCCAAA ATACCCTTGG AGTAAATGTG GAGCATAAAA CTACCTCTAA AGCATCCTTA 
AATCCTAGTG ATACACCTCC TTCTGTTGTA AATGAAGATT TTCTTCATGA CCTTAAAGAA 
ACTAATATTT CATATTCACA AGAGGCAGAT GATCGAGTAT TTAGAGCTCA TGGTCATTGT 
CTTCATGAGA TATTTTTGCT CAGGGAAGGA ATGTTTGAGC GAATTCCTGA TATAGTTTTA 
TGGCCAACAT GCCATGATGA TGTAGTTAAG ATTGTGAATC TAGCTTGCAA ATATAATCTT 
TGTATCATAC CAATTGGTGG AGGAACAAGT GTTTCATATG GCCTGATGTG TCCTGCAGAT 
GAGACAAGAA CAATTATTTC TTTGGACACT TCACAAATGA ATCGAATTCT CTGGGTTGAT 
GAGAACAATT TGACAGCTCA TGTAGAGGCT GGCATAACAG GACAAGAGTT GGAAAGACAG 
CTTAAAGAAA GTGGTTATTG TACAGGTCAT GAACCAGATT CCCTGGAGTT CAGTACTGTA 
GGAGGATGGG TATCTACTCG CGCATCAGGC ATGAAGAAGA ATATCTATGG CAATATCGAG 
GACCTGGTGG TTCATATAAA AATGGTAACA CCTAGAGGTA TAATAGAAAA AAGCTGTCAA 
GGACCTCGTA TGTCAACAGG CCCTGATATC CATCACTTCA TCATGGGATC TGAAGGAACT 
CTTGGTGTAA TAACAGAAGC TACAATAAAA ATCAGACCAG TCCCTGAATA CCAAAAGTAT 
GGCTCAGTAG CTTTCCCTAA TTTTGAACAA GGAGTAGCCT GTTTAAGAGA AATTGCAAAA 
CAGAGATGTG CTCCGGCATC TATTCGCCTC ATGGACAACA AGCAGTTTCA GTTTGGTCAT 
GCTCTTAAAC CTCAGGTTTC CTCTATTTTT ACATCATTTT TGGACGGATT AAAAAAGTTT 
TATATTACAA AGTTTAAAGG ATTTGACCCA AATCAGCTAA GTGTAGCCAC ATTACTGTTT 
GAGGGGGATC GTGAGAAGGT TCTTCAACAT GAAAAACAAG TGTATGATAT TGCTGCAAAA 
TTTGGTGGGT TGGCAGCTGG AGAAGATAAT GGACAGAGAG GTTATTTGCT GACCTATGTT 
ATTGCATACA TTCGAGACTT GGCTTTGGAA TACTATGTAT TAGGAGAATC TTTTGAGACT 
TCTGCTCCTT GGGACAGGGT GGTAGATCTC TGTAGAAATG TAAAAGAAAG AATAACAAGG 
GAATGCAAAG AGAAGGGTGT TCAGTTTGCT CCTTTTTCTA CATGCAGGGT GACGCAGACT 
TACGATGCAG GTGCTTGTAT CTACTTCTAT TTTGCCTTTA ACTACAGGGG AATTAGTGAC 
CCACTGACCG TATTTGAACA AACTGAGGCA GCTGCTAGAG AAGAAATCCT TGCTAATGGA 
GGGAGCCTGT CACATCACCA TGGAGTGGGC AAGTTACGGA AGCAATGGCT AAAGGAAAGT 
ATCTCTGATG TCGGCTTTGG GATGCTGAAG TCTGTCAAGG AATATGTGGA CCCCAATAAC 
ATCTTTGGAA ACAGAAACCT TTTATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

AGPS ( XM_011512043.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011510345.1 Homo sapiens alkylglycerone phosphate synthase (AGPS), transcript variant X3, mRNA.

Price & Availability↑

CloneID	OHu61937
Clone ID Related Accession (Same CDS sequence)	XM_011512043.2
Accession Version	XM_011512043.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1242bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	alkyldihydroxyacetonephosphate synthase, peroxisomal isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000002.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011512043.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTGTCCTG CAGATGAGAC AAGAACAATT ATTTCTTTGG ACACTTCACA AATGAATCGA 
ATTCTCTGGG TTGATGAGAA CAATTTGACA GCTCATGTAG AGGCTGGCAT AACAGGACAA 
GAGTTGGAAA GACAGCTTAA AGAAAGTGGT TATTGTACAG GTCATGAACC AGATTCCCTG 
GAGTTCAGTA CTGTAGGAGG ATGGGTATCT ACTCGCGCAT CAGGCATGAA GAAGAATATC 
TATGGCAATA TCGAGGACCT GGTGGTTCAT ATAAAAATGG TAACACCTAG AGGTATAATA 
GAAAAAAGCT GTCAAGGACC TCGTATGTCA ACAGGCCCTG ATATCCATCA CTTCATCATG 
GGATCTGAAG GAACTCTTGG TGTAATAACA GAAGCTACAA TAAAAATCAG ACCAGTCCCT 
GAATACCAAA AGTATGGCTC AGTAGCTTTC CCTAATTTTG AACAAGGAGT AGCCTGTTTA 
AGAGAAATTG CAAAACAGAG ATGTGCTCCG GCATCTATTC GCCTCATGGA CAACAAGCAG 
TTTCAGTTTG GTCATGCTCT TAAACCTCAG GTTTCCTCTA TTTTTACATC ATTTTTGGAC 
GGATTAAAAA AGTTTTATAT TACAAAGTTT AAAGGATTTG ACCCAAATCA GCTAAGTGTA 
GCCACATTAC TGTTTGAGGG GGATCGTGAG AAGGTTCTTC AACATGAAAA ACAAGTGTAT 
GATATTGCTG CAAAATTTGG TGGGTTGGCA GCTGGAGAAG ATAATGGACA GAGAGGTTAT 
TTGCTGACCT ATGTTATTGC ATACATTCGA GACTTGGCTT TGGAATACTA TGTATTAGGA 
GAATCTTTTG AGACTTCTGC TCCTTGGGAC AGGGTGGTAG ATCTCTGTAG AAATGTAAAA 
GAAAGAATAA CAAGGGAATG CAAAGAGAAG GGTGTTCAGT TTGCTCCTTT TTCTACATGC 
AGGGTGACGC AGACTTACGA TGCAGGTGCT TGTATCTACT TCTATTTTGC CTTTAACTAC 
AGGGGAATTA GTGACCCACT GACCGTATTT GAACAAACTG AGGCAGCTGC TAGAGAAGAA 
ATCCTTGCTA ATGGAGGGAG CCTGTCACAT CACCATGGAG TGGGCAAGTT ACGGAAGCAA 
TGGCTAAAGG AAAGTATCTC TGATGTCGGC TTTGGGATGC TGAAGTCTGT CAAGGAATAT 
GTGGACCCCA ATAACATCTT TGGAAACAGA AACCTTTTAT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011510345.1
CDS	1369..2610
Translation	MCPADETRTIISLDTSQMNRILWVDENNLTAHVEAGITGQELERQLKESGYCTGHEPDSLEFSTVGGWVSTRASGMKKNIYGNIEDLVVHIKMVTPRGIIEKSCQGPRMSTGPDIHHFIMGSEGTLGVITEATIKIRPVPEYQKYGSVAFPNFEQGVACLREIAKQRCAPASIRLMDNKQFQFGHALKPQVSSIFTSFLDGLKKFYITKFKGFDPNQLSVATLLFEGDREKVLQHEKQVYDIAAKFGGLAAGEDNGQRGYLLTYVIAYIRDLALEYYVLGESFETSAPWDRVVDLCRNVKERITRECKEKGVQFAPFSTCRVTQTYDAGACIYFYFAFNYRGISDPLTVFEQTEAAAREEILANGGSLSHHHGVGKLRKQWLKESISDVGFGMLKSVKEYVDPNNIFGNRNLL

Target ORF information:

RefSeq Version	XM_011512043.2
Organism	Homo sapiens(human)
Definition	Homo sapiens alkylglycerone phosphate synthase (AGPS), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011512043.2

ORF Insert Sequence:

ATGTGTCCTG CAGATGAGAC AAGAACAATT ATTTCTTTGG ACACTTCACA AATGAATCGA 
ATTCTCTGGG TTGATGAGAA CAATTTGACA GCTCATGTAG AGGCTGGCAT AACAGGACAA 
GAGTTGGAAA GACAGCTTAA AGAAAGTGGT TATTGTACAG GTCATGAACC AGATTCCCTG 
GAGTTCAGTA CTGTAGGAGG ATGGGTATCT ACTCGCGCAT CAGGCATGAA GAAGAATATC 
TATGGCAATA TCGAGGACCT GGTGGTTCAT ATAAAAATGG TAACACCTAG AGGTATAATA 
GAAAAAAGCT GTCAAGGACC TCGTATGTCA ACAGGCCCTG ATATCCATCA CTTCATCATG 
GGATCTGAAG GAACTCTTGG TGTAATAACA GAAGCTACAA TAAAAATCAG ACCAGTCCCT 
GAATACCAAA AGTATGGCTC AGTAGCTTTC CCTAATTTTG AACAAGGAGT AGCCTGTTTA 
AGAGAAATTG CAAAACAGAG ATGTGCTCCG GCATCTATTC GCCTCATGGA CAACAAGCAG 
TTTCAGTTTG GTCATGCTCT TAAACCTCAG GTTTCCTCTA TTTTTACATC ATTTTTGGAC 
GGATTAAAAA AGTTTTATAT TACAAAGTTT AAAGGATTTG ACCCAAATCA GCTAAGTGTA 
GCCACATTAC TGTTTGAGGG GGATCGTGAG AAGGTTCTTC AACATGAAAA ACAAGTGTAT 
GATATTGCTG CAAAATTTGG TGGGTTGGCA GCTGGAGAAG ATAATGGACA GAGAGGTTAT 
TTGCTGACCT ATGTTATTGC ATACATTCGA GACTTGGCTT TGGAATACTA TGTATTAGGA 
GAATCTTTTG AGACTTCTGC TCCTTGGGAC AGGGTGGTAG ATCTCTGTAG AAATGTAAAA 
GAAAGAATAA CAAGGGAATG CAAAGAGAAG GGTGTTCAGT TTGCTCCTTT TTCTACATGC 
AGGGTGACGC AGACTTACGA TGCAGGTGCT TGTATCTACT TCTATTTTGC CTTTAACTAC 
AGGGGAATTA GTGACCCACT GACCGTATTT GAACAAACTG AGGCAGCTGC TAGAGAAGAA 
ATCCTTGCTA ATGGAGGGAG CCTGTCACAT CACCATGGAG TGGGCAAGTT ACGGAAGCAA 
TGGCTAAAGG AAAGTATCTC TGATGTCGGC TTTGGGATGC TGAAGTCTGT CAAGGAATAT 
GTGGACCCCA ATAACATCTT TGGAAACAGA AACCTTTTAT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

The effect of benzyl isothiocyanate and its computer-aided design derivants targeting alkylglycerone phosphate synthase on the inhibition of human glioma U87MG cell line.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine36(5)3499-509(2015 May)
Zhu Y,Liu A,Zhang X,Qi L,Zhang L,Xue J,Liu Y,Yang P

Role and mechanism of the alkylglycerone phosphate synthase in suppressing the invasion potential of human glioma and hepatic carcinoma cells in vitro.
Oncology reports32(1)431-6(2014 Jul)
Zhu Y,Zhu L,Lu L,Zhang L,Zhang G,Wang Q,Yang P

Alkylglyceronephosphate synthase (AGPS) alters lipid signaling pathways and supports chemotherapy resistance of glioma and hepatic carcinoma cell lines.
Asian Pacific journal of cancer prevention : APJCP15(7)3219-26(2014)
Zhu Y,Liu XJ,Yang P,Zhao M,Lv LX,Zhang GD,Wang Q,Zhang L

Ether lipid generating enzyme AGPS alters the balance of structural and signaling lipids to fuel cancer pathogenicity.
Proceedings of the National Academy of Sciences of the United States of America110(37)14912-7(2013 Sep)
Benjamin DI,Cozzo A,Ji X,Roberts LS,Louie SM,Mulvihill MM,Luo K,Nomura DK

Functional characterization of novel mutations in GNPAT and AGPS, causing rhizomelic chondrodysplasia punctata (RCDP) types 2 and 3.
Human mutation33(1)189-97(2012 Jan)
Itzkovitz B,Jiralerspong S,Nimmo G,Loscalzo M,Horovitz DD,Snowden A,Moser A,Steinberg S,Braverman N

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AGPS cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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