BARX2 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	BARX2
Entrez Gene ID	8538
Full Name	BARX homeobox 2
General protein information	Preferred Names BARX homeobox 2 Names homeobox protein BarH-like 2 BarH-like homeobox 2
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 11 Map Location: 11q24.3
Summary	This gene encodes a member of the homeobox transcription factor family. A highly related protein in mouse has been shown to influence cellular processes that control cell adhesion and remodeling of the actin cytoskeleton in myoblast fusion and chondrogenesis. The encoded protein may also play a role in cancer progression. [provided by RefSeq, Jul 2008].
Disorder MIM:	604823

mRNA and Protein(s)

mRNA	Protein	Name
XM_011543043.1	XP_011541345.1	homeobox protein BarH-like 2 isoform X1
XM_011543044.2	XP_011541346.1	homeobox protein BarH-like 2 isoform X2
NM_003658.5	NP_003649.2	homeobox protein BarH-like 2
NM_003658.4	NP_003649.2	homeobox protein BarH-like 2

Pathways from BioSystems

Homologies

Homo sapiens (human)	BARX2	NP_003649.2
Pan troglodytes (chimpanzee)	BARX2	XP_522247.2
Mus musculus (house mouse)	Barx2	NP_038828.2
Xenopus tropicalis (tropical clawed frog)	barx2	XP_002934925.2
Canis lupus familiaris (dog)	BARX2	XP_851519.1
Rattus norvegicus (Norway rat)	Barx2	XP_003750505.1
Danio rerio (zebrafish)	barx2	XP_001342044.1
	BARX2	XP_001113572.1
Bos taurus (cattle)	BARX2	NP_001094736.1
Gallus gallus (chicken)	BARX2	NP_990227.1

Gene Ontology
Bibliography

Related articles in PubMed

Downregulation of BarH-like homeobox 2 promotes cell proliferation, migration and aerobic glycolysis through Wnt/?-catenin signaling, and predicts a poor prognosis in non-small cell lung carcinoma.
Chen H, Zhang M, Zhang W, Li Y, Zhu J, Zhang X, Zhao L, Zhu S, Chen B
Thoracic cancer(2018 Jan)

Down-regulation of Barx2 predicts poor survival in colorectal cancer.
Mi Y, Zhao S, Zhang W, Zhang D, Weng J, Huang K, Sun H, Tang H, Zhang X, Sun X, Peng Z, Wen Y
Biochemical and biophysical research communications478(1)67-73(2016 09)

Downregulation of homeobox gene Barx2 increases gastric cancer proliferation and metastasis and predicts poor patient outcomes.
Mi Y, Zhao S, Zhou C, Weng J, Li J, Wang Z, Sun H, Tang H, Zhang X, Sun X, Peng Z, Wen Y
Oncotarget7(37)60593-60608(2016 Sep)

A genome-wide association search for type 2 diabetes genes in African Americans.
Palmer ND, McDonough CW, Hicks PJ, Roh BH, Wing MR, An SS, Hester JM, Cooke JN, Bostrom MA, Rudock ME, Talbert ME, Lewis JP, , , Ferrara A, Lu L, Ziegler JT, Sale MM, Divers J, Shriner D, Adeyemo A, Rotimi CN, Ng MC, Langefeld CD, Freedman BI, Bowden DW, Voight BF, Scott LJ, Steinthorsdottir V, Morris AP, Dina C, Welch RP, Zeggini E, Huth C, Aulchenko YS, Thorleifsson G, McCulloch LJ, Ferreira T, Grallert H, Amin N, Wu G, Willer CJ, Raychaudhuri S, McCarroll SA, Langenberg C, Hofmann OM, Dupuis J, Qi L, Segr? AV, van Hoek M, Navarro P, Ardlie K, Balkau B, Benediktsson R, Bennett AJ, Blagieva R, Boerwinkle E, Bonnycastle LL, Bostr?m KB, Bravenboer B, Bumpstead S, Burtt NP, Charpentier G, Chines PS, Cornelis M, Couper DJ, Crawford G, Doney AS, Elliott KS, Elliott AL, Erdos MR, Fox CS, Franklin CS, Ganser M, Gieger C, Grarup N, Green T, Griffin S, Groves CJ, Guiducci C, Hadjadj S, Hassanali N, Herder C, Isomaa B, Jackson AU, Johnson PR, J?rgensen T, Kao WH, Klopp N, Kong A, Kraft P, Kuusisto J, Lauritzen T, Li M, Lieverse A, Lindgren CM, Lyssenko V, Marre M, Meitinger T, Midthjell K, Morken MA, Narisu N, Nilsson P, Owen KR, Payne F, Perry JR, Petersen AK, Platou C, Proen?a C, Prokopenko I, Rathmann W, Rayner NW, Robertson NR, Rocheleau G, Roden M, Sampson MJ, Saxena R, Shields BM, Shrader P, Sigurdsson G, Spars? T, Strassburger K, Stringham HM, Sun Q, Swift AJ, Thorand B, Tichet J, Tuomi T, van Dam RM, van Haeften TW, van Herpt T, van Vliet-Ostaptchouk JV, Walters GB, Weedon MN, Wijmenga C, Witteman J, Bergman RN, Cauchi S, Collins FS, Gloyn AL, Gyllensten U, Hansen T, Hide WA, Hitman GA, Hofman A, Hunter DJ, Hveem K, Laakso M, Mohlke KL, Morris AD, Palmer CN, Pramstaller PP, Rudan I, Sijbrands E, Stein LD, Tuomilehto J, Uitterlinden A, Walker M, Wareham NJ, Watanabe RM, Abecasis GR, Boehm BO, Campbell H, Daly MJ, Hattersley AT, Hu FB, Meigs JB, Pankow JS, Pedersen O, Wichmann HE, Barroso I, Florez JC, Frayling TM, Groop L, Sladek R, Thorsteinsdottir U, Wilson JF, Illig T, Froguel P, van Duijn CM, Stefansson K, Altshuler D, Boehnke M, McCarthy MI, Soranzo N, Wheeler E, Glazer NL, Bouatia-Naji N, M?gi R, Randall J, Johnson T, Elliott P, Rybin D, Henneman P, Dehghan A, Hottenga JJ, Song K, Goel A, Egan JM, Lajunen T, Doney A, Kanoni S, Cavalcanti-Proen?a C, Kumari M, Timpson NJ, Zabena C, Ingelsson E, An P, O'Connell J, Luan J, Elliott A, McCarroll SA, Roccasecca RM, Pattou F, Sethupathy P, Ariyurek Y, Barter P, Beilby JP, Ben-Shlomo Y, Bergmann S, Bochud M, Bonnefond A, Borch-Johnsen K, B?ttcher Y, Brunner E, Bumpstead SJ, Chen YD, Chines P, Clarke R, Coin LJ, Cooper MN, Crisponi L, Day IN, de Geus EJ, Delplanque J, Fedson AC, Fischer-Rosinsky A, Forouhi NG, Frants R, Franzosi MG, Galan P, Goodarzi MO, Graessler J, Grundy S, Gwilliam R, Hallmans G, Hammond N, Han X, Hartikainen AL, Hayward C, Heath SC, Hercberg S, Hicks AA, Hillman DR, Hingorani AD, Hui J, Hung J, Jula A, Kaakinen M, Kaprio J, Kesaniemi YA, Kivimaki M, Knight B, Koskinen S, Kovacs P, Kyvik KO, Lathrop GM, Lawlor DA, Le Bacquer O, Lecoeur C, Li Y, Mahley R, Mangino M, Manning AK, Mart?nez-Larrad MT, McAteer JB, McPherson R, Meisinger C, Melzer D, Meyre D, Mitchell BD, Mukherjee S, Naitza S, Neville MJ, Oostra BA, Orr? M, Pakyz R, Paolisso G, Pattaro C, Pearson D, Peden JF, Pedersen NL, Perola M, Pfeiffer AF, Pichler I, Polasek O, Posthuma D, Potter SC, Pouta A, Province MA, Psaty BM, Rayner NW, Rice K, Ripatti S, Rivadeneira F, Rolandsson O, Sandbaek A, Sandhu M, Sanna S, Sayer AA, Scheet P, Seedorf U, Sharp SJ, Shields B, Sijbrands EJ, Silveira A, Simpson L, Singleton A, Smith NL, Sovio U, Swift A, Syddall H, Syv?nen AC, Tanaka T, T?njes A, Uitterlinden AG, van Dijk KW, Varma D, Visvikis-Siest S, Vitart V, Vogelzangs N, Waeber G, Wagner PJ, Walley A, Ward KL, Watkins H, Wild SH, Willemsen G, Witteman JC, Yarnell JW, Zelenika D, Zethelius B, Zhai G, Zhao JH, Zillikens MC, Borecki IB, Loos RJ, Meneton P, Magnusson PK, Nathan DM, Williams GH, Silander K, Salomaa V, Smith GD, Bornstein SR, Schwarz P, Spranger J, Karpe F, Shuldiner AR, Cooper C, Dedoussis GV, Serrano-R?os M, Lind L, Palmer LJ, Franks PW, Ebrahim S, Marmot M, Kao WH, Pramstaller PP, Wright AF, Stumvoll M, Hamsten A, Buchanan TA, Valle TT, Rotter JI, Siscovick DS, Penninx BW, Boomsma DI, Deloukas P, Spector TD, Ferrucci L, Cao A, Scuteri A, Schlessinger D, Uda M, Ruokonen A, Jarvelin MR, Waterworth DM, Vollenweider P, Peltonen L, Mooser V, Sladek R
PloS one7(1)e29202(2012)

Genome-wide association study in east Asians identifies novel susceptibility loci for breast cancer.
Long J, Cai Q, Sung H, Shi J, Zhang B, Choi JY, Wen W, Delahanty RJ, Lu W, Gao YT, Shen H, Park SK, Chen K, Shen CY, Ren Z, Haiman CA, Matsuo K, Kim MK, Khoo US, Iwasaki M, Zheng Y, Xiang YB, Gu K, Rothman N, Wang W, Hu Z, Liu Y, Yoo KY, Noh DY, Han BG, Lee MH, Zheng H, Zhang L, Wu PE, Shieh YL, Chan SY, Wang S, Xie X, Kim SW, Henderson BE, Le Marchand L, Ito H, Kasuga Y, Ahn SH, Kang HS, Chan KY, Iwata H, Tsugane S, Li C, Shu XO, Kang DH, Zheng W
PLoS genetics8(2)e1002532(2012)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Down-regulation of Barx2 is associated with advanced clinical factors of colorectal cancer and predicts poor survival.
Title: Down-regulation of Barx2 predicts poor survival in colorectal cancer.

Observational study of gene-disease association. (HuGE Navigator)
Title: Maternal genes and facial clefts in offspring: a comprehensive search for genetic associations in two population-based cleft studies from Scandinavia.

BARX2 can coordinate the expression of a network of genes that influence the growth of tumor cells
Title: Identification of novel binding elements and gene targets for the homeodomain protein BARX2.

The following BARX2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the BARX2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu30656	NM_003658.5 Latest version!	Homo sapiens BARX homeobox 2 (BARX2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$154.50-$216.30 $309.00
OHu61935	XM_011543044.2 Latest version!	Homo sapiens BARX homeobox 2 (BARX2), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00
OHu61934	XM_011543043.1 Latest version!	Homo sapiens BARX homeobox 2 (BARX2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
View Old Accession Versions >>
OHu30656	NM_003658.4	Homo sapiens BARX homeobox 2 (BARX2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$154.50-$216.30 $309.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

BARX2 ( NM_003658.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_003649.2 Homo sapiens BARX homeobox 2 (BARX2), mRNA.

Price & Availability↑

CloneID	OHu30656
Clone ID Related Accession (Same CDS sequence)	NM_003658.5 , NM_003658.4
Accession Version	NM_003658.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 840bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-24
Organism	Homo sapiens(human)
Product	homeobox protein BarH-like 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AP003775.3 and BC111432.1. On May 17, 2019 this sequence version replaced NM_003658.4. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AJ243512.1, AF031924.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA1968832 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000281437.6/ ENSP00000281437.4 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGCACTGCC ACGCCGAGCT GAGGCTGAGC TCGCCCGGCC AGCTCAAAGC AGCCAGGCGG 
CGCTACAAGA CTTTCATGAT CGACGAGATC CTCTCCAAGG AGACCTGCGA TTACTTTGAG 
AAACTTTCCC TCTACTCCGT GTGCCCGTCG CTGGTCGTGC GACCCAAGCC CCTGCATTCC 
TGTACGGGCT CCCCTTCCCT GCGGGCATAT CCGCTCCTCT CGGTGATCAC CCGCCAGCCC 
ACTGTCATCT CCCACCTGGT CCCTGCCACC CCGGGAATCG CCCAGGCACT GTCCTGCCAC 
CAGGTCACCG AGGCGGTCTC TGCTGAGGCC CCAGGGGGCG AGGCCCTAGC CAGCAGCGAG 
TCAGAGACGG AACAGCCCAC GCCCCGACAG AAGAAGCCCC GCCGGAGTCG CACCATCTTC 
ACCGAGCTGC AGCTCATGGG CCTGGAGAAG AAATTCCAGA AGCAGAAGTA TTTGTCAACC 
CCAGACAGGT TGGACTTGGC TCAGTCTCTG GGACTCACTC AGCTGCAGGT GAAGACCTGG 
TATCAGAATC GCAGGATGAA ATGGAAGAAA ATGGTTCTTA AAGGTGGACA GGAAGCACCC 
ACAAAACCCA AAGGTCGCCC CAAGAAGAAC TCCATCCCCA CATCAGAAGA GATTGAAGCT 
GAAGAGAAGA TGAACAGCCA GGCCCAGGGT CAGGAGCAGC TGGAGCCCTC TCAGGGGCAG 
GAGGAGCTCT GTGAAGCACA GGAACCGAAA GCACGTGATG TCCCCTTAGA GATGGCAGAG 
CCACCAGACC CGCCCCAGGA GTTGCCAATA CCCTCTTCGG AACCCCCACC ATTAAGCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_003649.2
CDS	189..1028
Translation	MHCHAELRLSSPGQLKAARRRYKTFMIDEILSKETCDYFEKLSLYSVCPSLVVRPKPLHSCTGSPSLRAYPLLSVITRQPTVISHLVPATPGIAQALSCHQVTEAVSAEAPGGEALASSESETEQPTPRQKKPRRSRTIFTELQLMGLEKKFQKQKYLSTPDRLDLAQSLGLTQLQVKTWYQNRRMKWKKMVLKGGQEAPTKPKGRPKKNSIPTSEEIEAEEKMNSQAQGQEQLEPSQGQEELCEAQEPKARDVPLEMAEPPDPPQELPIPSSEPPPLS

Target ORF information:

RefSeq Version	NM_003658.5
Organism	Homo sapiens(human)
Definition	Homo sapiens BARX homeobox 2 (BARX2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_003658.5

ORF Insert Sequence:

ATGCACTGCC ACGCCGAGCT GAGGCTGAGC TCGCCCGGCC AGCTCAAAGC AGCCAGGCGG 
CGCTACAAGA CTTTCATGAT CGACGAGATC CTCTCCAAGG AGACCTGCGA TTACTTTGAG 
AAACTTTCCC TCTACTCCGT GTGCCCGTCG CTGGTCGTGC GACCCAAGCC CCTGCATTCC 
TGTACGGGCT CCCCTTCCCT GCGGGCATAT CCGCTCCTCT CGGTGATCAC CCGCCAGCCC 
ACTGTCATCT CCCACCTGGT CCCTGCCACC CCGGGAATCG CCCAGGCACT GTCCTGCCAC 
CAGGTCACCG AGGCGGTCTC TGCTGAGGCC CCAGGGGGCG AGGCCCTAGC CAGCAGCGAG 
TCAGAGACGG AACAGCCCAC GCCCCGACAG AAGAAGCCCC GCCGGAGTCG CACCATCTTC 
ACCGAGCTGC AGCTCATGGG CCTGGAGAAG AAATTCCAGA AGCAGAAGTA TTTGTCAACC 
CCAGACAGGT TGGACTTGGC TCAGTCTCTG GGACTCACTC AGCTGCAGGT GAAGACCTGG 
TATCAGAATC GCAGGATGAA ATGGAAGAAA ATGGTTCTTA AAGGTGGACA GGAAGCACCC 
ACAAAACCCA AAGGTCGCCC CAAGAAGAAC TCCATCCCCA CATCAGAAGA GATTGAAGCT 
GAAGAGAAGA TGAACAGCCA GGCCCAGGGT CAGGAGCAGC TGGAGCCCTC TCAGGGGCAG 
GAGGAGCTCT GTGAAGCACA GGAACCGAAA GCACGTGATG TCCCCTTAGA GATGGCAGAG 
CCACCAGACC CGCCCCAGGA GTTGCCAATA CCCTCTTCGG AACCCCCACC ATTAAGCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

BARX2 ( NM_003658.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_003649.2 Homo sapiens BARX homeobox 2 (BARX2), mRNA.

Price & Availability↑

CloneID	OHu30656
Clone ID Related Accession (Same CDS sequence)	NM_003658.5 , NM_003658.4
Accession Version	NM_003658.4	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 840bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-12-22
Organism	Homo sapiens(human)
Product	homeobox protein BarH-like 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AP003775.3 and BC111432.1. On Jul 24, 2007 this sequence version replaced NM_003658.3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC069378.1, AJ243512.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA1968832 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCACTGCC ACGCCGAGCT GAGGCTGAGC TCGCCCGGCC AGCTCAAAGC AGCCAGGCGG 
CGCTACAAGA CTTTCATGAT CGACGAGATC CTCTCCAAGG AGACCTGCGA TTACTTTGAG 
AAACTTTCCC TCTACTCCGT GTGCCCGTCG CTGGTCGTGC GACCCAAGCC CCTGCATTCC 
TGTACGGGCT CCCCTTCCCT GCGGGCATAT CCGCTCCTCT CGGTGATCAC CCGCCAGCCC 
ACTGTCATCT CCCACCTGGT CCCTGCCACC CCGGGAATCG CCCAGGCACT GTCCTGCCAC 
CAGGTCACCG AGGCGGTCTC TGCTGAGGCC CCAGGGGGCG AGGCCCTAGC CAGCAGCGAG 
TCAGAGACGG AACAGCCCAC GCCCCGACAG AAGAAGCCCC GCCGGAGTCG CACCATCTTC 
ACCGAGCTGC AGCTCATGGG CCTGGAGAAG AAATTCCAGA AGCAGAAGTA TTTGTCAACC 
CCAGACAGGT TGGACTTGGC TCAGTCTCTG GGACTCACTC AGCTGCAGGT GAAGACCTGG 
TATCAGAATC GCAGGATGAA ATGGAAGAAA ATGGTTCTTA AAGGTGGACA GGAAGCACCC 
ACAAAACCCA AAGGTCGCCC CAAGAAGAAC TCCATCCCCA CATCAGAAGA GATTGAAGCT 
GAAGAGAAGA TGAACAGCCA GGCCCAGGGT CAGGAGCAGC TGGAGCCCTC TCAGGGGCAG 
GAGGAGCTCT GTGAAGCACA GGAACCGAAA GCACGTGATG TCCCCTTAGA GATGGCAGAG 
CCACCAGACC CGCCCCAGGA GTTGCCAATA CCCTCTTCGG AACCCCCACC ATTAAGCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_003649.2
CDS	51..890
Translation	MHCHAELRLSSPGQLKAARRRYKTFMIDEILSKETCDYFEKLSLYSVCPSLVVRPKPLHSCTGSPSLRAYPLLSVITRQPTVISHLVPATPGIAQALSCHQVTEAVSAEAPGGEALASSESETEQPTPRQKKPRRSRTIFTELQLMGLEKKFQKQKYLSTPDRLDLAQSLGLTQLQVKTWYQNRRMKWKKMVLKGGQEAPTKPKGRPKKNSIPTSEEIEAEEKMNSQAQGQEQLEPSQGQEELCEAQEPKARDVPLEMAEPPDPPQELPIPSSEPPPLS

Target ORF information:

RefSeq Version	NM_003658.4
Organism	Homo sapiens(human)
Definition	Homo sapiens BARX homeobox 2 (BARX2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_003658.4

ORF Insert Sequence:

ATGCACTGCC ACGCCGAGCT GAGGCTGAGC TCGCCCGGCC AGCTCAAAGC AGCCAGGCGG 
CGCTACAAGA CTTTCATGAT CGACGAGATC CTCTCCAAGG AGACCTGCGA TTACTTTGAG 
AAACTTTCCC TCTACTCCGT GTGCCCGTCG CTGGTCGTGC GACCCAAGCC CCTGCATTCC 
TGTACGGGCT CCCCTTCCCT GCGGGCATAT CCGCTCCTCT CGGTGATCAC CCGCCAGCCC 
ACTGTCATCT CCCACCTGGT CCCTGCCACC CCGGGAATCG CCCAGGCACT GTCCTGCCAC 
CAGGTCACCG AGGCGGTCTC TGCTGAGGCC CCAGGGGGCG AGGCCCTAGC CAGCAGCGAG 
TCAGAGACGG AACAGCCCAC GCCCCGACAG AAGAAGCCCC GCCGGAGTCG CACCATCTTC 
ACCGAGCTGC AGCTCATGGG CCTGGAGAAG AAATTCCAGA AGCAGAAGTA TTTGTCAACC 
CCAGACAGGT TGGACTTGGC TCAGTCTCTG GGACTCACTC AGCTGCAGGT GAAGACCTGG 
TATCAGAATC GCAGGATGAA ATGGAAGAAA ATGGTTCTTA AAGGTGGACA GGAAGCACCC 
ACAAAACCCA AAGGTCGCCC CAAGAAGAAC TCCATCCCCA CATCAGAAGA GATTGAAGCT 
GAAGAGAAGA TGAACAGCCA GGCCCAGGGT CAGGAGCAGC TGGAGCCCTC TCAGGGGCAG 
GAGGAGCTCT GTGAAGCACA GGAACCGAAA GCACGTGATG TCCCCTTAGA GATGGCAGAG 
CCACCAGACC CGCCCCAGGA GTTGCCAATA CCCTCTTCGG AACCCCCACC ATTAAGCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

BARX2 ( XM_011543044.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011541346.1 Homo sapiens BARX homeobox 2 (BARX2), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu61935
Clone ID Related Accession (Same CDS sequence)	XM_011543044.2
Accession Version	XM_011543044.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 405bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	homeobox protein BarH-like 2 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000011.10) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011543044.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGCCTGG AGAAGAAATT CCAGAAGCAG AAGTATTTGT CAACCCCAGA CAGGTTGGAC 
TTGGCTCAGT CTCTGGGACT CACTCAGCTG CAGGTGAAGA CCTGGTATCA GAATCGCAGG 
ATGAAATGGA AGAAAATGGT TCTTAAAGGT GGACAGGAAG CACCCACAAA ACCCAAAGGT 
CGCCCCAAGA AGAACTCCAT CCCCACATCA GAAGAGATTG AAGCTGAAGA GAAGATGAAC 
AGCCAGGCCC AGGGTCAGGA GCAGCTGGAG CCCTCTCAGG GGCAGGAGGA GCTCTGTGAA 
GCACAGGAAC CGAAAGCACG TGATGTCCCC TTAGAGATGG CAGAGCCACC AGACCCGCCC 
CAGGAGTTGC CAATACCCTC TTCGGAACCC CCACCATTAA GCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011541346.1
CDS	331..735
Translation	MGLEKKFQKQKYLSTPDRLDLAQSLGLTQLQVKTWYQNRRMKWKKMVLKGGQEAPTKPKGRPKKNSIPTSEEIEAEEKMNSQAQGQEQLEPSQGQEELCEAQEPKARDVPLEMAEPPDPPQELPIPSSEPPPLS

Target ORF information:

RefSeq Version	XM_011543044.2
Organism	Homo sapiens(human)
Definition	Homo sapiens BARX homeobox 2 (BARX2), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011543044.2

ORF Insert Sequence:

ATGGGCCTGG AGAAGAAATT CCAGAAGCAG AAGTATTTGT CAACCCCAGA CAGGTTGGAC 
TTGGCTCAGT CTCTGGGACT CACTCAGCTG CAGGTGAAGA CCTGGTATCA GAATCGCAGG 
ATGAAATGGA AGAAAATGGT TCTTAAAGGT GGACAGGAAG CACCCACAAA ACCCAAAGGT 
CGCCCCAAGA AGAACTCCAT CCCCACATCA GAAGAGATTG AAGCTGAAGA GAAGATGAAC 
AGCCAGGCCC AGGGTCAGGA GCAGCTGGAG CCCTCTCAGG GGCAGGAGGA GCTCTGTGAA 
GCACAGGAAC CGAAAGCACG TGATGTCCCC TTAGAGATGG CAGAGCCACC AGACCCGCCC 
CAGGAGTTGC CAATACCCTC TTCGGAACCC CCACCATTAA GCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

BARX2 ( XM_011543043.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_011541345.1 Homo sapiens BARX homeobox 2 (BARX2), transcript variant X1, mRNA.

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CloneID	OHu61934
Clone ID Related Accession (Same CDS sequence)	XM_011543043.1
Accession Version	XM_011543043.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 702bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	homeobox protein BarH-like 2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000011.10) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCACATCA ACTGCCTGGA AGACAGAATG TCAGAAAGGA AAGTCTCTGG CTCCCCTTCC 
CTGCGGGCAT ATCCGCTCCT CTCGGTGATC ACCCGCCAGC CCACTGTCAT CTCCCACCTG 
GTCCCTGCCA CCCCGGGAAT CGCCCAGGCA CTGTCCTGCC ACCAGGTCAC CGAGGCGGTC 
TCTGCTGAGG CCCCAGGGGG CGAGGCCCTA GCCAGCAGCG AGTCAGAGAC GGAACAGCCC 
ACGCCCCGAC AGAAGAAGCC CCGCCGGAGT CGCACCATCT TCACCGAGCT GCAGCTCATG 
GGCCTGGAGA AGAAATTCCA GAAGCAGAAG TATTTGTCAA CCCCAGACAG GTTGGACTTG 
GCTCAGTCTC TGGGACTCAC TCAGCTGCAG GTGAAGACCT GGTATCAGAA TCGCAGGATG 
AAATGGAAGA AAATGGTTCT TAAAGGTGGA CAGGAAGCAC CCACAAAACC CAAAGGTCGC 
CCCAAGAAGA ACTCCATCCC CACATCAGAA GAGATTGAAG CTGAAGAGAA GATGAACAGC 
CAGGCCCAGG GTCAGGAGCA GCTGGAGCCC TCTCAGGGGC AGGAGGAGCT CTGTGAAGCA 
CAGGAACCGA AAGCACGTGA TGTCCCCTTA GAGATGGCAG AGCCACCAGA CCCGCCCCAG 
GAGTTGCCAA TACCCTCTTC GGAACCCCCA CCATTAAGCT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011541345.1
CDS	16..717
Translation	MHINCLEDRMSERKVSGSPSLRAYPLLSVITRQPTVISHLVPATPGIAQALSCHQVTEAVSAEAPGGEALASSESETEQPTPRQKKPRRSRTIFTELQLMGLEKKFQKQKYLSTPDRLDLAQSLGLTQLQVKTWYQNRRMKWKKMVLKGGQEAPTKPKGRPKKNSIPTSEEIEAEEKMNSQAQGQEQLEPSQGQEELCEAQEPKARDVPLEMAEPPDPPQELPIPSSEPPPLS

Target ORF information:

RefSeq Version	XM_011543043.1
Organism	Homo sapiens(human)
Definition	Homo sapiens BARX homeobox 2 (BARX2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011543043.1

ORF Insert Sequence:

ATGCACATCA ACTGCCTGGA AGACAGAATG TCAGAAAGGA AAGTCTCTGG CTCCCCTTCC 
CTGCGGGCAT ATCCGCTCCT CTCGGTGATC ACCCGCCAGC CCACTGTCAT CTCCCACCTG 
GTCCCTGCCA CCCCGGGAAT CGCCCAGGCA CTGTCCTGCC ACCAGGTCAC CGAGGCGGTC 
TCTGCTGAGG CCCCAGGGGG CGAGGCCCTA GCCAGCAGCG AGTCAGAGAC GGAACAGCCC 
ACGCCCCGAC AGAAGAAGCC CCGCCGGAGT CGCACCATCT TCACCGAGCT GCAGCTCATG 
GGCCTGGAGA AGAAATTCCA GAAGCAGAAG TATTTGTCAA CCCCAGACAG GTTGGACTTG 
GCTCAGTCTC TGGGACTCAC TCAGCTGCAG GTGAAGACCT GGTATCAGAA TCGCAGGATG 
AAATGGAAGA AAATGGTTCT TAAAGGTGGA CAGGAAGCAC CCACAAAACC CAAAGGTCGC 
CCCAAGAAGA ACTCCATCCC CACATCAGAA GAGATTGAAG CTGAAGAGAA GATGAACAGC 
CAGGCCCAGG GTCAGGAGCA GCTGGAGCCC TCTCAGGGGC AGGAGGAGCT CTGTGAAGCA 
CAGGAACCGA AAGCACGTGA TGTCCCCTTA GAGATGGCAG AGCCACCAGA CCCGCCCCAG 
GAGTTGCCAA TACCCTCTTC GGAACCCCCA CCATTAAGCT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Downregulation of BarH-like homeobox 2 promotes cell proliferation, migration and aerobic glycolysis through Wnt/?-catenin signaling, and predicts a poor prognosis in non-small cell lung carcinoma.
Thoracic cancer(2018 Jan)
Chen H,Zhang M,Zhang W,Li Y,Zhu J,Zhang X,Zhao L,Zhu S,Chen B

Down-regulation of Barx2 predicts poor survival in colorectal cancer.
Biochemical and biophysical research communications478(1)67-73(2016 09)
Mi Y,Zhao S,Zhang W,Zhang D,Weng J,Huang K,Sun H,Tang H,Zhang X,Sun X,Peng Z,Wen Y

Downregulation of homeobox gene Barx2 increases gastric cancer proliferation and metastasis and predicts poor patient outcomes.
Oncotarget7(37)60593-60608(2016 Sep)
Mi Y,Zhao S,Zhou C,Weng J,Li J,Wang Z,Sun H,Tang H,Zhang X,Sun X,Peng Z,Wen Y

A genome-wide association search for type 2 diabetes genes in African Americans.
PloS one7(1)e29202(2012)
Palmer ND,McDonough CW,Hicks PJ,Roh BH,Wing MR,An SS,Hester JM,Cooke JN,Bostrom MA,Rudock ME,Talbert ME,Lewis JP,,,Ferrara A,Lu L,Ziegler JT,Sale MM,Divers J,Shriner D,Adeyemo A,Rotimi CN,Ng MC,Langefeld CD,Freedman BI,Bowden DW,Voight BF,Scott LJ,Steinthorsdottir V,Morris AP,Dina C,Welch RP,Zeggini E,Huth C,Aulchenko YS,Thorleifsson G,McCulloch LJ,Ferreira T,Grallert H,Amin N,Wu G,Willer CJ,Raychaudhuri S,McCarroll SA,Langenberg C,Hofmann OM,Dupuis J,Qi L,Segr? AV,van Hoek M,Navarro P,Ardlie K,Balkau B,Benediktsson R,Bennett AJ,Blagieva R,Boerwinkle E,Bonnycastle LL,Bostr?m KB,Bravenboer B,Bumpstead S,Burtt NP,Charpentier G,Chines PS,Cornelis M,Couper DJ,Crawford G,Doney AS,Elliott KS,Elliott AL,Erdos MR,Fox CS,Franklin CS,Ganser M,Gieger C,Grarup N,Green T,Griffin S,Groves CJ,Guiducci C,Hadjadj S,Hassanali N,Herder C,Isomaa B,Jackson AU,Johnson PR,J?rgensen T,Kao WH,Klopp N,Kong A,Kraft P,Kuusisto J,Lauritzen T,Li M,Lieverse A,Lindgren CM,Lyssenko V,Marre M,Meitinger T,Midthjell K,Morken MA,Narisu N,Nilsson P,Owen KR,Payne F,Perry JR,Petersen AK,Platou C,Proen?a C,Prokopenko I,Rathmann W,Rayner NW,Robertson NR,Rocheleau G,Roden M,Sampson MJ,Saxena R,Shields BM,Shrader P,Sigurdsson G,Spars? T,Strassburger K,Stringham HM,Sun Q,Swift AJ,Thorand B,Tichet J,Tuomi T,van Dam RM,van Haeften TW,van Herpt T,van Vliet-Ostaptchouk JV,Walters GB,Weedon MN,Wijmenga C,Witteman J,Bergman RN,Cauchi S,Collins FS,Gloyn AL,Gyllensten U,Hansen T,Hide WA,Hitman GA,Hofman A,Hunter DJ,Hveem K,Laakso M,Mohlke KL,Morris AD,Palmer CN,Pramstaller PP,Rudan I,Sijbrands E,Stein LD,Tuomilehto J,Uitterlinden A,Walker M,Wareham NJ,Watanabe RM,Abecasis GR,Boehm BO,Campbell H,Daly MJ,Hattersley AT,Hu FB,Meigs JB,Pankow JS,Pedersen O,Wichmann HE,Barroso I,Florez JC,Frayling TM,Groop L,Sladek R,Thorsteinsdottir U,Wilson JF,Illig T,Froguel P,van Duijn CM,Stefansson K,Altshuler D,Boehnke M,McCarthy MI,Soranzo N,Wheeler E,Glazer NL,Bouatia-Naji N,M?gi R,Randall J,Johnson T,Elliott P,Rybin D,Henneman P,Dehghan A,Hottenga JJ,Song K,Goel A,Egan JM,Lajunen T,Doney A,Kanoni S,Cavalcanti-Proen?a C,Kumari M,Timpson NJ,Zabena C,Ingelsson E,An P,O'Connell J,Luan J,Elliott A,McCarroll SA,Roccasecca RM,Pattou F,Sethupathy P,Ariyurek Y,Barter P,Beilby JP,Ben-Shlomo Y,Bergmann S,Bochud M,Bonnefond A,Borch-Johnsen K,B?ttcher Y,Brunner E,Bumpstead SJ,Chen YD,Chines P,Clarke R,Coin LJ,Cooper MN,Crisponi L,Day IN,de Geus EJ,Delplanque J,Fedson AC,Fischer-Rosinsky A,Forouhi NG,Frants R,Franzosi MG,Galan P,Goodarzi MO,Graessler J,Grundy S,Gwilliam R,Hallmans G,Hammond N,Han X,Hartikainen AL,Hayward C,Heath SC,Hercberg S,Hicks AA,Hillman DR,Hingorani AD,Hui J,Hung J,Jula A,Kaakinen M,Kaprio J,Kesaniemi YA,Kivimaki M,Knight B,Koskinen S,Kovacs P,Kyvik KO,Lathrop GM,Lawlor DA,Le Bacquer O,Lecoeur C,Li Y,Mahley R,Mangino M,Manning AK,Mart?nez-Larrad MT,McAteer JB,McPherson R,Meisinger C,Melzer D,Meyre D,Mitchell BD,Mukherjee S,Naitza S,Neville MJ,Oostra BA,Orr? M,Pakyz R,Paolisso G,Pattaro C,Pearson D,Peden JF,Pedersen NL,Perola M,Pfeiffer AF,Pichler I,Polasek O,Posthuma D,Potter SC,Pouta A,Province MA,Psaty BM,Rayner NW,Rice K,Ripatti S,Rivadeneira F,Rolandsson O,Sandbaek A,Sandhu M,Sanna S,Sayer AA,Scheet P,Seedorf U,Sharp SJ,Shields B,Sijbrands EJ,Silveira A,Simpson L,Singleton A,Smith NL,Sovio U,Swift A,Syddall H,Syv?nen AC,Tanaka T,T?njes A,Uitterlinden AG,van Dijk KW,Varma D,Visvikis-Siest S,Vitart V,Vogelzangs N,Waeber G,Wagner PJ,Walley A,Ward KL,Watkins H,Wild SH,Willemsen G,Witteman JC,Yarnell JW,Zelenika D,Zethelius B,Zhai G,Zhao JH,Zillikens MC,Borecki IB,Loos RJ,Meneton P,Magnusson PK,Nathan DM,Williams GH,Silander K,Salomaa V,Smith GD,Bornstein SR,Schwarz P,Spranger J,Karpe F,Shuldiner AR,Cooper C,Dedoussis GV,Serrano-R?os M,Lind L,Palmer LJ,Franks PW,Ebrahim S,Marmot M,Kao WH,Pramstaller PP,Wright AF,Stumvoll M,Hamsten A,Buchanan TA,Valle TT,Rotter JI,Siscovick DS,Penninx BW,Boomsma DI,Deloukas P,Spector TD,Ferrucci L,Cao A,Scuteri A,Schlessinger D,Uda M,Ruokonen A,Jarvelin MR,Waterworth DM,Vollenweider P,Peltonen L,Mooser V,Sladek R

Genome-wide association study in east Asians identifies novel susceptibility loci for breast cancer.
PLoS genetics8(2)e1002532(2012)
Long J,Cai Q,Sung H,Shi J,Zhang B,Choi JY,Wen W,Delahanty RJ,Lu W,Gao YT,Shen H,Park SK,Chen K,Shen CY,Ren Z,Haiman CA,Matsuo K,Kim MK,Khoo US,Iwasaki M,Zheng Y,Xiang YB,Gu K,Rothman N,Wang W,Hu Z,Liu Y,Yoo KY,Noh DY,Han BG,Lee MH,Zheng H,Zhang L,Wu PE,Shieh YL,Chan SY,Wang S,Xie X,Kim SW,Henderson BE,Le Marchand L,Ito H,Kasuga Y,Ahn SH,Kang HS,Chan KY,Iwata H,Tsugane S,Li C,Shu XO,Kang DH,Zheng W

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BARX2 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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