ITGA8 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	ITGA8
Entrez Gene ID	8516
Full Name	integrin subunit alpha 8
General protein information	Preferred Names integrin subunit alpha 8 Names integrin alpha-8 integrin, alpha 8
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 10 Map Location: 10p13
Summary	Integrins are heterodimeric transmembrane receptor proteins that mediate numerous cellular processes including cell adhesion, cytoskeletal rearrangement, and activation of cell signaling pathways. Integrins are composed of alpha and beta subunits. This gene encodes the alpha 8 subunit of the heterodimeric integrin alpha8beta1 protein. The encoded protein is a single-pass type 1 membrane protein that contains multiple FG-GAP repeats. This repeat is predicted to fold into a beta propeller structure. This gene regulates the recruitment of mesenchymal cells into epithelial structures, mediates cell-cell interactions, and regulates neurite outgrowth of sensory and motor neurons. The integrin alpha8beta1 protein thus plays an important role in wound-healing and organogenesis. Mutations in this gene have been associated with renal hypodysplasia/aplasia-1 (RHDA1) and with several animal models of chronic kidney disease. Alternate splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Apr 2014].
Disorder MIM:	604063
Disorder Html:	Renal hypodysplasia/aplasia 1, 191830 (3)

mRNA and Protein(s)

mRNA	Protein	Name
XM_011519752.2	XP_011518054.1	integrin alpha-8 isoform X1
NM_001291494.1	NP_001278423.1	integrin alpha-8 isoform 2 preproprotein
NM_003638.3	NP_003629.2	integrin alpha-8 isoform 1 preproprotein
NM_003638.2	NP_003629.2	integrin alpha-8 Isoform 1 preproprotein

Pathways from BioSystems

Homologies

Gallus gallus (chicken)	ITGA8	NP_990619.1
Caenorhabditis elegans (roundworm)	pat-2	NP_498948.1
Pan troglodytes (chimpanzee)	ITGA8	XP_507671.2
Bos taurus (cattle)	ITGA8	XP_002692127.1
	ITGA8	XP_001089317.1
Drosophila melanogaster (fruit fly)	if	NP_001162778.1
Canis lupus familiaris (dog)	ITGA8	XP_005617255.1
Mus musculus (house mouse)	Itga8	NP_001001309.1
Homo sapiens (human)	ITGA8	NP_003629.1
Rattus norvegicus (Norway rat)	Itga8	NP_001167443.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP000032	XP_311131.5
Xenopus tropicalis (tropical clawed frog)	itga8	XP_002939074.2

Gene Ontology
Bibliography

Related articles in PubMed

ITGA2B and ITGA8 are predictive of prognosis in clear cell renal cell carcinoma patients.
Lu X, Wan F, Zhang H, Shi G, Ye D
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine37(1)253-62(2016 Jan)

Mild recessive mutations in six Fraser syndrome-related genes cause isolated congenital anomalies of the kidney and urinary tract.
Kohl S, Hwang DY, Dworschak GC, Hilger AC, Saisawat P, Vivante A, Stajic N, Bogdanovic R, Reutter HM, Kehinde EO, Tasic V, Hildebrandt F
Journal of the American Society of Nephrology : JASN25(9)1917-22(2014 Sep)

Integrin alpha 8 recessive mutations are responsible for bilateral renal agenesis in humans.
Humbert C, Silbermann F, Morar B, Parisot M, Zarhrate M, Masson C, Tores F, Blanchet P, Perez MJ, Petrov Y, Khau Van Kien P, Roume J, Leroy B, Gribouval O, Kalaydjieva L, Heidet L, Salomon R, Antignac C, Benmerah A, Saunier S, Jeanpierre C
American journal of human genetics94(2)288-94(2014 Feb)

Genome-wide association study of chronic periodontitis in a general German population.
Teumer A, Holtfreter B, V?lker U, Petersmann A, Nauck M, Biffar R, V?lzke H, Kroemer HK, Meisel P, Homuth G, Kocher T
Journal of clinical periodontology40(11)977-85(2013 Nov)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

ITGA2B and ITGA8 have roles in prognosis in clear cell renal cell carcinoma patients
Title: ITGA2B and ITGA8 are predictive of prognosis in clear cell renal cell carcinoma patients.

In 15 of 590 families, we identified recessive mutations in the genes FRAS1, FREM2, GRIP1, FREM1, ITGA8, and GREM1, all of which function in the interaction of the ureteric bud and the metanephric mesenchyme.
Title: Mild recessive mutations in six Fraser syndrome-related genes cause isolated congenital anomalies of the kidney and urinary tract.

Mutations of ITGA8 are a genetic cause of bilateral renal agenesis and that, at least in some cases, bilateral renal agenesis is an autosomal-recessive disease.
Title: Integrin alpha 8 recessive mutations are responsible for bilateral renal agenesis in humans.

the ITGA8 gene might have gender-specific roles in the development of schizophrenia.
Title: A missense mutation in the ITGA8 gene, a cell adhesion molecule gene, is associated with schizophrenia in Japanese female patients.

Analysis of the data demonstrated that Itga8 expression is CArG box-serum response factor independent, but myocardin dependent through an as yet unknown sequence module that is distal from the promoter region.
Title: Expression and promoter analysis of a highly restricted integrin alpha gene in vascular smooth muscle.

The following ITGA8 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the ITGA8 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu23698	NM_003638.3 Latest version!	Homo sapiens integrin subunit alpha 8 (ITGA8), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$539.50-$755.30 $1079.00
OHu61909	XM_011519752.2 Latest version!	Homo sapiens integrin subunit alpha 8 (ITGA8), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$391.30 $559.00
OHu16978	NM_001291494.1 Latest version!	Homo sapiens integrin subunit alpha 8 (ITGA8), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	20	$559.30 $799.00
View Old Accession Versions >>
OHu23698	NM_003638.2	Homo sapiens integrin subunit alpha 8 (ITGA8), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$539.50-$755.30 $1079.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

ITGA8 ( NM_003638.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_003629.2 Homo sapiens integrin subunit alpha 8 (ITGA8), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu23698
Clone ID Related Accession (Same CDS sequence)	NM_003638.3 , NM_003638.2
Accession Version	NM_003638.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3192bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-26
Organism	Homo sapiens(human)
Product	integrin alpha-8 isoform 1 preproprotein
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DB237365.1, DC425586.1, AK297740.1, L36531.1, AL590636.12 and BU735798.1. This sequence is a reference standard in the RefSeqGene project. On Nov 23, 2018 this sequence version replaced NM_003638.2. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660809.95988.1, SRR1660803.194784.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000378076.4/ ENSP00000367316.3 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGTCGCCCG GGGCCAGCCG CGGTCCCCGG GGAAGCCAGG CGCCGCTGAT CGCGCCCCTC 
TGCTGCGCCG CGGCCGCGCT GGGGATGTTG CTGTGGTCCC CCGCCTGTCA GGCGTTCAAC 
CTGGACGTGG AAAAGCTCAC AGTGTACAGC GGCCCCAAGG GCAGCTACTT CGGCTACGCC 
GTGGACTTCC ACATACCCGA CGCCCGCACA GCGAGTGTCT TGGTGGGGGC GCCCAAAGCC 
AACACCAGCC AGCCCGATAT CGTGGAAGGG GGAGCCGTCT ATTACTGTCC TTGGCCCGCG 
GAGGGGTCTG CGCAGTGCAG GCAGATACCG TTTGACACCA CCAACAACAG AAAGATCAGA 
GTTAATGGAA CCAAAGAACC TATCGAGTTC AAATCCAATC AGTGGTTTGG AGCAACAGTG 
AAAGCTCACA AAGGAAAAGT TGTGGCCTGT GCTCCTTTAT ATCACTGGAG AACTCTTAAA 
CCGACACCAG AAAAGGACCC AGTTGGCACC TGCTATGTAG CAATTCAGAA CTTCAGCGCC 
TATGCCGAGT TCTCTCCTTG CCGGAACAGC AATGCTGATC CGGAAGGCCA GGGTTACTGC 
CAAGCAGGAT TTAGTCTGGA TTTTTATAAG AATGGAGACC TTATTGTGGG AGGACCTGGG 
AGTTTCTACT GGCAAGGACA AGTGATCACT GCCAGTGTTG CAGATATCAT TGCAAATTAC 
TCATTCAAGG ATATCCTCAG GAAACTGGCA GGAGAAAAGC AGACGGAAGT GGCTCCAGCT 
TCCTATGATG ACAGTTACCT TGGATACTCA GTTGCTGCTG GGGAGTTTAC TGGGGATTCT 
CAGCAAGAAT TGGTTGCTGG AATTCCAAGA GGAGCACAGA ATTTTGGATA TGTTTCCATC 
ATTAACTCTA CGGATATGAC GTTTATTCAG AATTTCACGG GAGAACAGAT GGCATCTTAT 
TTTGGATATA CCGTTGTCGT ATCAGATGTT AACAGTGATG GACTGGATGA TGTCCTGGTT 
GGGGCACCTC TCTTTATGGA ACGTGAATTT GAGAGCAACC CCAGAGAAGT AGGGCAAATC 
TACCTGTATT TGCAAGTGAG CTCTCTCCTC TTCAGAGACC CCCAGATCCT CACTGGCACC 
GAGACGTTTG GGAGATTCGG TAGTGCTATG GCACACTTAG GAGACCTGAA CCAAGATGGA 
TACAATGACA TTGCCATCGG AGTGCCTTTT GCAGGCAAGG ATCAAAGAGG CAAAGTGCTC 
ATTTATAATG GGAACAAAGA TGGCTTAAAC ACCAAGCCTT CCCAAGTTCT GCAAGGAGTG 
TGGGCCTCAC ATGCTGTCCC TTCCGGATTT GGCTTTACTT TAAGAGGAGA TTCAGACATA 
GACAAGAATG ATTACCCAGA TTTGATTGTG GGTGCATTTG GAACAGGAAA AGTCGCTGTT 
TACAGAGCAA GACCGGTTGT GACTGTAGAT GCCCAGCTTC TGCTGCACCC AATGATTATC 
AATCTTGAAA ATAAAACTTG CCAGGTTCCA GACTCTATGA CATCTGCTGC CTGCTTTTCT 
TTAAGAGTAT GTGCATCTGT CACAGGCCAG AGCATTGCAA ACACAATAGT CTTGATGGCA 
GAGGTGCAAT TAGATTCCCT GAAACAGAAA GGAGCTATTA AACGGACGCT CTTCCTTGAT 
AACCATCAGG CTCATCGCGT CTTCCCTCTT GTGATAAAAA GGCAGAAATC CCACCAGTGC 
CAGGATTTCA TCGTTTACCT TCGAGATGAA ACTGAATTCC GAGATAAATT ATCTCCAATC 
AACATTAGTT TGAATTACAG TTTGGACGAA TCCACCTTTA AAGAAGGCCT GGAAGTGAAA 
CCAATATTGA ACTACTACAG AGAAAACATT GTTAGTGAAC AGGCTCACAT TCTGGTGGAC 
TGTGGAGAAG ACAATCTGTG TGTTCCTGAC TTGAAGCTGT CGGCTAGACC AGATAAGCAT 
CAGGTAATCA TTGGAGATGA AAATCACCTT ATGCTCATAA TAAATGCAAG AAATGAAGGG 
GAAGGAGCAT ATGAAGCTGA ACTCTTTGTA ATGATACCAG AAGAGGCAGA TTATGTTGGA 
ATCGAACGCA ACAACAAGGG ATTTCGACCA CTGAGCTGTG AGTACAAGAT GGAAAATGTA 
ACCAGGATGG TGGTGTGTGA CCTTGGGAAC CCTATGGTGT CTGGAACAAA TTATTCCCTG 
GGCCTCCGAT TTGCAGTTCC ACGTCTTGAG AAAACAAACA TGAGCATTAA CTTCGATCTC 
CAAATCAGAA GTTCCAACAA GGACAATCCA GACAGCAATT TTGTGAGCCT GCAAATCAAC 
ATCACTGCTG TAGCGCAGGT GGAAATAAGA GGAGTGTCAC ACCCTCCGCA GATTGTTCTG 
CCCATTCATA ACTGGGAACC AGAAGAGGAG CCCCACAAAG AGGAGGAGGT TGGACCATTG 
GTGGAACATA TTTATGAGCT GCACAATATT GGACCAAGTA CCATCAGTGA CACCATCCTG 
GAGGTGGGCT GGCCTTTCTC TGCCCGGGAT GAATTTCTTC TCTATATTTT CCATATTCAA 
ACTCTGGGAC CTCTGCAGTG CCAACCAAAT CCTAATATCA ATCCACAGGA TATAAAGCCT 
GCTGCCTCCC CAGAGGACAC CCCTGAGCTC AGCGCCTTTT TGCGAAACTC TACTATTCCT 
CATCTTGTCA GGAAGAGGGA TGTACATGTG GTCGAATTCC ACAGACAGAG CCCTGCAAAA 
ATACTGAATT GTACAAATAT CGAGTGTTTA CAAATCTCCT GTGCAGTGGG ACGACTCGAA 
GGAGGAGAAA GCGCAGTCCT GAAAGTCAGG TCACGATTAT GGGCCCACAC CTTCCTCCAG 
AGAAAAAATG ATCCCTATGC TCTTGCATCC CTGGTGTCCT TTGAAGTTAA GAAGATGCCT 
TATACAGATC AGCCAGCAAA ACTCCCAGAA GGAAGCATAG TAATTAAGAC ATCAGTTATT 
TGGGCAACTC CGAATGTTTC CTTCTCAATC CCATTATGGG TAATAATACT AGCAATACTT 
CTTGGATTGT TGGTTCTCGC CATTTTAACC TTAGCTTTAT GGAAGTGTGG ATTCTTTGAC 
AGAGCCAGAC CTCCTCAGGA GGACATGACC GACAGGGAAC AGCTGACAAA TGACAAGACC 
CCTGAGGCAT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_003629.2
CDS	152..3343
Translation	MSPGASRGPRGSQAPLIAPLCCAAAALGMLLWSPACQAFNLDVEKLTVYSGPKGSYFGYAVDFHIPDARTASVLVGAPKANTSQPDIVEGGAVYYCPWPAEGSAQCRQIPFDTTNNRKIRVNGTKEPIEFKSNQWFGATVKAHKGKVVACAPLYHWRTLKPTPEKDPVGTCYVAIQNFSAYAEFSPCRNSNADPEGQGYCQAGFSLDFYKNGDLIVGGPGSFYWQGQVITASVADIIANYSFKDILRKLAGEKQTEVAPASYDDSYLGYSVAAGEFTGDSQQELVAGIPRGAQNFGYVSIINSTDMTFIQNFTGEQMASYFGYTVVVSDVNSDGLDDVLVGAPLFMEREFESNPREVGQIYLYLQVSSLLFRDPQILTGTETFGRFGSAMAHLGDLNQDGYNDIAIGVPFAGKDQRGKVLIYNGNKDGLNTKPSQVLQGVWASHAVPSGFGFTLRGDSDIDKNDYPDLIVGAFGTGKVAVYRARPVVTVDAQLLLHPMIINLENKTCQVPDSMTSAACFSLRVCASVTGQSIANTIVLMAEVQLDSLKQKGAIKRTLFLDNHQAHRVFPLVIKRQKSHQCQDFIVYLRDETEFRDKLSPINISLNYSLDESTFKEGLEVKPILNYYRENIVSEQAHILVDCGEDNLCVPDLKLSARPDKHQVIIGDENHLMLIINARNEGEGAYEAELFVMIPEEADYVGIERNNKGFRPLSCEYKMENVTRMVVCDLGNPMVSGTNYSLGLRFAVPRLEKTNMSINFDLQIRSSNKDNPDSNFVSLQINITAVAQVEIRGVSHPPQIVLPIHNWEPEEEPHKEEEVGPLVEHIYELHNIGPSTISDTILEVGWPFSARDEFLLYIFHIQTLGPLQCQPNPNINPQDIKPAASPEDTPELSAFLRNSTIPHLVRKRDVHVVEFHRQSPAKILNCTNIECLQISCAVGRLEGGESAVLKVRSRLWAHTFLQRKNDPYALASLVSFEVKKMPYTDQPAKLPEGSIVIKTSVIWATPNVSFSIPLWVIILAILLGLLVLAILTLALWKCGFFDRARPPQEDMTDREQLTNDKTPEA

Target ORF information:

RefSeq Version	NM_003638.3
Organism	Homo sapiens(human)
Definition	Homo sapiens integrin subunit alpha 8 (ITGA8), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_003638.3

ORF Insert Sequence:

ATGTCGCCCG GGGCCAGCCG CGGTCCCCGG GGAAGCCAGG CGCCGCTGAT CGCGCCCCTC 
TGCTGCGCCG CGGCCGCGCT GGGGATGTTG CTGTGGTCCC CCGCCTGTCA GGCGTTCAAC 
CTGGACGTGG AAAAGCTCAC AGTGTACAGC GGCCCCAAGG GCAGCTACTT CGGCTACGCC 
GTGGACTTCC ACATACCCGA CGCCCGCACA GCGAGTGTCT TGGTGGGGGC GCCCAAAGCC 
AACACCAGCC AGCCCGATAT CGTGGAAGGG GGAGCCGTCT ATTACTGTCC TTGGCCCGCG 
GAGGGGTCTG CGCAGTGCAG GCAGATACCG TTTGACACCA CCAACAACAG AAAGATCAGA 
GTTAATGGAA CCAAAGAACC TATCGAGTTC AAATCCAATC AGTGGTTTGG AGCAACAGTG 
AAAGCTCACA AAGGAAAAGT TGTGGCCTGT GCTCCTTTAT ATCACTGGAG AACTCTTAAA 
CCGACACCAG AAAAGGACCC AGTTGGCACC TGCTATGTAG CAATTCAGAA CTTCAGCGCC 
TATGCCGAGT TCTCTCCTTG CCGGAACAGC AATGCTGATC CGGAAGGCCA GGGTTACTGC 
CAAGCAGGAT TTAGTCTGGA TTTTTATAAG AATGGAGACC TTATTGTGGG AGGACCTGGG 
AGTTTCTACT GGCAAGGACA AGTGATCACT GCCAGTGTTG CAGATATCAT TGCAAATTAC 
TCATTCAAGG ATATCCTCAG GAAACTGGCA GGAGAAAAGC AGACGGAAGT GGCTCCAGCT 
TCCTATGATG ACAGTTACCT TGGATACTCA GTTGCTGCTG GGGAGTTTAC TGGGGATTCT 
CAGCAAGAAT TGGTTGCTGG AATTCCAAGA GGAGCACAGA ATTTTGGATA TGTTTCCATC 
ATTAACTCTA CGGATATGAC GTTTATTCAG AATTTCACGG GAGAACAGAT GGCATCTTAT 
TTTGGATATA CCGTTGTCGT ATCAGATGTT AACAGTGATG GACTGGATGA TGTCCTGGTT 
GGGGCACCTC TCTTTATGGA ACGTGAATTT GAGAGCAACC CCAGAGAAGT AGGGCAAATC 
TACCTGTATT TGCAAGTGAG CTCTCTCCTC TTCAGAGACC CCCAGATCCT CACTGGCACC 
GAGACGTTTG GGAGATTCGG TAGTGCTATG GCACACTTAG GAGACCTGAA CCAAGATGGA 
TACAATGACA TTGCCATCGG AGTGCCTTTT GCAGGCAAGG ATCAAAGAGG CAAAGTGCTC 
ATTTATAATG GGAACAAAGA TGGCTTAAAC ACCAAGCCTT CCCAAGTTCT GCAAGGAGTG 
TGGGCCTCAC ATGCTGTCCC TTCCGGATTT GGCTTTACTT TAAGAGGAGA TTCAGACATA 
GACAAGAATG ATTACCCAGA TTTGATTGTG GGTGCATTTG GAACAGGAAA AGTCGCTGTT 
TACAGAGCAA GACCGGTTGT GACTGTAGAT GCCCAGCTTC TGCTGCACCC AATGATTATC 
AATCTTGAAA ATAAAACTTG CCAGGTTCCA GACTCTATGA CATCTGCTGC CTGCTTTTCT 
TTAAGAGTAT GTGCATCTGT CACAGGCCAG AGCATTGCAA ACACAATAGT CTTGATGGCA 
GAGGTGCAAT TAGATTCCCT GAAACAGAAA GGAGCTATTA AACGGACGCT CTTCCTTGAT 
AACCATCAGG CTCATCGCGT CTTCCCTCTT GTGATAAAAA GGCAGAAATC CCACCAGTGC 
CAGGATTTCA TCGTTTACCT TCGAGATGAA ACTGAATTCC GAGATAAATT ATCTCCAATC 
AACATTAGTT TGAATTACAG TTTGGACGAA TCCACCTTTA AAGAAGGCCT GGAAGTGAAA 
CCAATATTGA ACTACTACAG AGAAAACATT GTTAGTGAAC AGGCTCACAT TCTGGTGGAC 
TGTGGAGAAG ACAATCTGTG TGTTCCTGAC TTGAAGCTGT CGGCTAGACC AGATAAGCAT 
CAGGTAATCA TTGGAGATGA AAATCACCTT ATGCTCATAA TAAATGCAAG AAATGAAGGG 
GAAGGAGCAT ATGAAGCTGA ACTCTTTGTA ATGATACCAG AAGAGGCAGA TTATGTTGGA 
ATCGAACGCA ACAACAAGGG ATTTCGACCA CTGAGCTGTG AGTACAAGAT GGAAAATGTA 
ACCAGGATGG TGGTGTGTGA CCTTGGGAAC CCTATGGTGT CTGGAACAAA TTATTCCCTG 
GGCCTCCGAT TTGCAGTTCC ACGTCTTGAG AAAACAAACA TGAGCATTAA CTTCGATCTC 
CAAATCAGAA GTTCCAACAA GGACAATCCA GACAGCAATT TTGTGAGCCT GCAAATCAAC 
ATCACTGCTG TAGCGCAGGT GGAAATAAGA GGAGTGTCAC ACCCTCCGCA GATTGTTCTG 
CCCATTCATA ACTGGGAACC AGAAGAGGAG CCCCACAAAG AGGAGGAGGT TGGACCATTG 
GTGGAACATA TTTATGAGCT GCACAATATT GGACCAAGTA CCATCAGTGA CACCATCCTG 
GAGGTGGGCT GGCCTTTCTC TGCCCGGGAT GAATTTCTTC TCTATATTTT CCATATTCAA 
ACTCTGGGAC CTCTGCAGTG CCAACCAAAT CCTAATATCA ATCCACAGGA TATAAAGCCT 
GCTGCCTCCC CAGAGGACAC CCCTGAGCTC AGCGCCTTTT TGCGAAACTC TACTATTCCT 
CATCTTGTCA GGAAGAGGGA TGTACATGTG GTCGAATTCC ACAGACAGAG CCCTGCAAAA 
ATACTGAATT GTACAAATAT CGAGTGTTTA CAAATCTCCT GTGCAGTGGG ACGACTCGAA 
GGAGGAGAAA GCGCAGTCCT GAAAGTCAGG TCACGATTAT GGGCCCACAC CTTCCTCCAG 
AGAAAAAATG ATCCCTATGC TCTTGCATCC CTGGTGTCCT TTGAAGTTAA GAAGATGCCT 
TATACAGATC AGCCAGCAAA ACTCCCAGAA GGAAGCATAG TAATTAAGAC ATCAGTTATT 
TGGGCAACTC CGAATGTTTC CTTCTCAATC CCATTATGGG TAATAATACT AGCAATACTT 
CTTGGATTGT TGGTTCTCGC CATTTTAACC TTAGCTTTAT GGAAGTGTGG ATTCTTTGAC 
AGAGCCAGAC CTCCTCAGGA GGACATGACC GACAGGGAAC AGCTGACAAA TGACAAGACC 
CCTGAGGCAT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ITGA8 ( NM_003638.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_003629.2 Homo sapiens integrin subunit alpha 8 (ITGA8), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu23698
Clone ID Related Accession (Same CDS sequence)	NM_003638.3 , NM_003638.2
Accession Version	NM_003638.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3192bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-06-25
Organism	Homo sapiens(human)
Product	integrin alpha-8 Isoform 1 preproprotein
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DB237365.1, DC425586.1, AK297740.1, L36531.1, AL590636.12 and BU735798.1. This sequence is a reference standard in the RefSeqGene project. On Apr 17, 2014 this sequence version replaced NM_003638.1. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660809.95988.1, SRR1660803.194784.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: full length.

ATGTCGCCCG GGGCCAGCCG CGGTCCCCGG GGAAGCCAGG CGCCGCTGAT CGCGCCCCTC 
TGCTGCGCCG CGGCCGCGCT GGGGATGTTG CTGTGGTCCC CCGCCTGTCA GGCGTTCAAC 
CTGGACGTGG AAAAGCTCAC AGTGTACAGC GGCCCCAAGG GCAGCTACTT CGGCTACGCC 
GTGGACTTCC ACATACCCGA CGCCCGCACA GCGAGTGTCT TGGTGGGGGC GCCCAAAGCC 
AACACCAGCC AGCCCGATAT CGTGGAAGGG GGAGCCGTCT ATTACTGTCC TTGGCCCGCG 
GAGGGGTCTG CGCAGTGCAG GCAGATACCG TTTGACACCA CCAACAACAG AAAGATCAGA 
GTTAATGGAA CCAAAGAACC TATCGAGTTC AAATCCAATC AGTGGTTTGG AGCAACAGTG 
AAAGCTCACA AAGGAAAAGT TGTGGCCTGT GCTCCTTTAT ATCACTGGAG AACTCTTAAA 
CCGACACCAG AAAAGGACCC AGTTGGCACC TGCTATGTAG CAATTCAGAA CTTCAGCGCC 
TATGCCGAGT TCTCTCCTTG CCGGAACAGC AATGCTGATC CGGAAGGCCA GGGTTACTGC 
CAAGCAGGAT TTAGTCTGGA TTTTTATAAG AATGGAGACC TTATTGTGGG AGGACCTGGG 
AGTTTCTACT GGCAAGGACA AGTGATCACT GCCAGTGTTG CAGATATCAT TGCAAATTAC 
TCATTCAAGG ATATCCTCAG GAAACTGGCA GGAGAAAAGC AGACGGAAGT GGCTCCAGCT 
TCCTATGATG ACAGTTACCT TGGATACTCA GTTGCTGCTG GGGAGTTTAC TGGGGATTCT 
CAGCAAGAAT TGGTTGCTGG AATTCCAAGA GGAGCACAGA ATTTTGGATA TGTTTCCATC 
ATTAACTCTA CGGATATGAC GTTTATTCAG AATTTCACGG GAGAACAGAT GGCATCTTAT 
TTTGGATATA CCGTTGTCGT ATCAGATGTT AACAGTGATG GACTGGATGA TGTCCTGGTT 
GGGGCACCTC TCTTTATGGA ACGTGAATTT GAGAGCAACC CCAGAGAAGT AGGGCAAATC 
TACCTGTATT TGCAAGTGAG CTCTCTCCTC TTCAGAGACC CCCAGATCCT CACTGGCACC 
GAGACGTTTG GGAGATTCGG TAGTGCTATG GCACACTTAG GAGACCTGAA CCAAGATGGA 
TACAATGACA TTGCCATCGG AGTGCCTTTT GCAGGCAAGG ATCAAAGAGG CAAAGTGCTC 
ATTTATAATG GGAACAAAGA TGGCTTAAAC ACCAAGCCTT CCCAAGTTCT GCAAGGAGTG 
TGGGCCTCAC ATGCTGTCCC TTCCGGATTT GGCTTTACTT TAAGAGGAGA TTCAGACATA 
GACAAGAATG ATTACCCAGA TTTGATTGTG GGTGCATTTG GAACAGGAAA AGTCGCTGTT 
TACAGAGCAA GACCGGTTGT GACTGTAGAT GCCCAGCTTC TGCTGCACCC AATGATTATC 
AATCTTGAAA ATAAAACTTG CCAGGTTCCA GACTCTATGA CATCTGCTGC CTGCTTTTCT 
TTAAGAGTAT GTGCATCTGT CACAGGCCAG AGCATTGCAA ACACAATAGT CTTGATGGCA 
GAGGTGCAAT TAGATTCCCT GAAACAGAAA GGAGCTATTA AACGGACGCT CTTCCTTGAT 
AACCATCAGG CTCATCGCGT CTTCCCTCTT GTGATAAAAA GGCAGAAATC CCACCAGTGC 
CAGGATTTCA TCGTTTACCT TCGAGATGAA ACTGAATTCC GAGATAAATT ATCTCCAATC 
AACATTAGTT TGAATTACAG TTTGGACGAA TCCACCTTTA AAGAAGGCCT GGAAGTGAAA 
CCAATATTGA ACTACTACAG AGAAAACATT GTTAGTGAAC AGGCTCACAT TCTGGTGGAC 
TGTGGAGAAG ACAATCTGTG TGTTCCTGAC TTGAAGCTGT CGGCTAGACC AGATAAGCAT 
CAGGTAATCA TTGGAGATGA AAATCACCTT ATGCTCATAA TAAATGCAAG AAATGAAGGG 
GAAGGAGCAT ATGAAGCTGA ACTCTTTGTA ATGATACCAG AAGAGGCAGA TTATGTTGGA 
ATCGAACGCA ACAACAAGGG ATTTCGACCA CTGAGCTGTG AGTACAAGAT GGAAAATGTA 
ACCAGGATGG TGGTGTGTGA CCTTGGGAAC CCTATGGTGT CTGGAACAAA TTATTCCCTG 
GGCCTCCGAT TTGCAGTTCC ACGTCTTGAG AAAACAAACA TGAGCATTAA CTTCGATCTC 
CAAATCAGAA GTTCCAACAA GGACAATCCA GACAGCAATT TTGTGAGCCT GCAAATCAAC 
ATCACTGCTG TAGCGCAGGT GGAAATAAGA GGAGTGTCAC ACCCTCCGCA GATTGTTCTG 
CCCATTCATA ACTGGGAACC AGAAGAGGAG CCCCACAAAG AGGAGGAGGT TGGACCATTG 
GTGGAACATA TTTATGAGCT GCACAATATT GGACCAAGTA CCATCAGTGA CACCATCCTG 
GAGGTGGGCT GGCCTTTCTC TGCCCGGGAT GAATTTCTTC TCTATATTTT CCATATTCAA 
ACTCTGGGAC CTCTGCAGTG CCAACCAAAT CCTAATATCA ATCCACAGGA TATAAAGCCT 
GCTGCCTCCC CAGAGGACAC CCCTGAGCTC AGCGCCTTTT TGCGAAACTC TACTATTCCT 
CATCTTGTCA GGAAGAGGGA TGTACATGTG GTCGAATTCC ACAGACAGAG CCCTGCAAAA 
ATACTGAATT GTACAAATAT CGAGTGTTTA CAAATCTCCT GTGCAGTGGG ACGACTCGAA 
GGAGGAGAAA GCGCAGTCCT GAAAGTCAGG TCACGATTAT GGGCCCACAC CTTCCTCCAG 
AGAAAAAATG ATCCCTATGC TCTTGCATCC CTGGTGTCCT TTGAAGTTAA GAAGATGCCT 
TATACAGATC AGCCAGCAAA ACTCCCAGAA GGAAGCATAG TAATTAAGAC ATCAGTTATT 
TGGGCAACTC CGAATGTTTC CTTCTCAATC CCATTATGGG TAATAATACT AGCAATACTT 
CTTGGATTGT TGGTTCTCGC CATTTTAACC TTAGCTTTAT GGAAGTGTGG ATTCTTTGAC 
AGAGCCAGAC CTCCTCAGGA GGACATGACC GACAGGGAAC AGCTGACAAA TGACAAGACC 
CCTGAGGCAT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_003629.2
CDS	565..3756
Translation	MSPGASRGPRGSQAPLIAPLCCAAAALGMLLWSPACQAFNLDVEKLTVYSGPKGSYFGYAVDFHIPDARTASVLVGAPKANTSQPDIVEGGAVYYCPWPAEGSAQCRQIPFDTTNNRKIRVNGTKEPIEFKSNQWFGATVKAHKGKVVACAPLYHWRTLKPTPEKDPVGTCYVAIQNFSAYAEFSPCRNSNADPEGQGYCQAGFSLDFYKNGDLIVGGPGSFYWQGQVITASVADIIANYSFKDILRKLAGEKQTEVAPASYDDSYLGYSVAAGEFTGDSQQELVAGIPRGAQNFGYVSIINSTDMTFIQNFTGEQMASYFGYTVVVSDVNSDGLDDVLVGAPLFMEREFESNPREVGQIYLYLQVSSLLFRDPQILTGTETFGRFGSAMAHLGDLNQDGYNDIAIGVPFAGKDQRGKVLIYNGNKDGLNTKPSQVLQGVWASHAVPSGFGFTLRGDSDIDKNDYPDLIVGAFGTGKVAVYRARPVVTVDAQLLLHPMIINLENKTCQVPDSMTSAACFSLRVCASVTGQSIANTIVLMAEVQLDSLKQKGAIKRTLFLDNHQAHRVFPLVIKRQKSHQCQDFIVYLRDETEFRDKLSPINISLNYSLDESTFKEGLEVKPILNYYRENIVSEQAHILVDCGEDNLCVPDLKLSARPDKHQVIIGDENHLMLIINARNEGEGAYEAELFVMIPEEADYVGIERNNKGFRPLSCEYKMENVTRMVVCDLGNPMVSGTNYSLGLRFAVPRLEKTNMSINFDLQIRSSNKDNPDSNFVSLQINITAVAQVEIRGVSHPPQIVLPIHNWEPEEEPHKEEEVGPLVEHIYELHNIGPSTISDTILEVGWPFSARDEFLLYIFHIQTLGPLQCQPNPNINPQDIKPAASPEDTPELSAFLRNSTIPHLVRKRDVHVVEFHRQSPAKILNCTNIECLQISCAVGRLEGGESAVLKVRSRLWAHTFLQRKNDPYALASLVSFEVKKMPYTDQPAKLPEGSIVIKTSVIWATPNVSFSIPLWVIILAILLGLLVLAILTLALWKCGFFDRARPPQEDMTDREQLTNDKTPEA

Target ORF information:

RefSeq Version	NM_003638.2
Organism	Homo sapiens(human)
Definition	Homo sapiens integrin subunit alpha 8 (ITGA8), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_003638.2

ORF Insert Sequence:

ATGTCGCCCG GGGCCAGCCG CGGTCCCCGG GGAAGCCAGG CGCCGCTGAT CGCGCCCCTC 
TGCTGCGCCG CGGCCGCGCT GGGGATGTTG CTGTGGTCCC CCGCCTGTCA GGCGTTCAAC 
CTGGACGTGG AAAAGCTCAC AGTGTACAGC GGCCCCAAGG GCAGCTACTT CGGCTACGCC 
GTGGACTTCC ACATACCCGA CGCCCGCACA GCGAGTGTCT TGGTGGGGGC GCCCAAAGCC 
AACACCAGCC AGCCCGATAT CGTGGAAGGG GGAGCCGTCT ATTACTGTCC TTGGCCCGCG 
GAGGGGTCTG CGCAGTGCAG GCAGATACCG TTTGACACCA CCAACAACAG AAAGATCAGA 
GTTAATGGAA CCAAAGAACC TATCGAGTTC AAATCCAATC AGTGGTTTGG AGCAACAGTG 
AAAGCTCACA AAGGAAAAGT TGTGGCCTGT GCTCCTTTAT ATCACTGGAG AACTCTTAAA 
CCGACACCAG AAAAGGACCC AGTTGGCACC TGCTATGTAG CAATTCAGAA CTTCAGCGCC 
TATGCCGAGT TCTCTCCTTG CCGGAACAGC AATGCTGATC CGGAAGGCCA GGGTTACTGC 
CAAGCAGGAT TTAGTCTGGA TTTTTATAAG AATGGAGACC TTATTGTGGG AGGACCTGGG 
AGTTTCTACT GGCAAGGACA AGTGATCACT GCCAGTGTTG CAGATATCAT TGCAAATTAC 
TCATTCAAGG ATATCCTCAG GAAACTGGCA GGAGAAAAGC AGACGGAAGT GGCTCCAGCT 
TCCTATGATG ACAGTTACCT TGGATACTCA GTTGCTGCTG GGGAGTTTAC TGGGGATTCT 
CAGCAAGAAT TGGTTGCTGG AATTCCAAGA GGAGCACAGA ATTTTGGATA TGTTTCCATC 
ATTAACTCTA CGGATATGAC GTTTATTCAG AATTTCACGG GAGAACAGAT GGCATCTTAT 
TTTGGATATA CCGTTGTCGT ATCAGATGTT AACAGTGATG GACTGGATGA TGTCCTGGTT 
GGGGCACCTC TCTTTATGGA ACGTGAATTT GAGAGCAACC CCAGAGAAGT AGGGCAAATC 
TACCTGTATT TGCAAGTGAG CTCTCTCCTC TTCAGAGACC CCCAGATCCT CACTGGCACC 
GAGACGTTTG GGAGATTCGG TAGTGCTATG GCACACTTAG GAGACCTGAA CCAAGATGGA 
TACAATGACA TTGCCATCGG AGTGCCTTTT GCAGGCAAGG ATCAAAGAGG CAAAGTGCTC 
ATTTATAATG GGAACAAAGA TGGCTTAAAC ACCAAGCCTT CCCAAGTTCT GCAAGGAGTG 
TGGGCCTCAC ATGCTGTCCC TTCCGGATTT GGCTTTACTT TAAGAGGAGA TTCAGACATA 
GACAAGAATG ATTACCCAGA TTTGATTGTG GGTGCATTTG GAACAGGAAA AGTCGCTGTT 
TACAGAGCAA GACCGGTTGT GACTGTAGAT GCCCAGCTTC TGCTGCACCC AATGATTATC 
AATCTTGAAA ATAAAACTTG CCAGGTTCCA GACTCTATGA CATCTGCTGC CTGCTTTTCT 
TTAAGAGTAT GTGCATCTGT CACAGGCCAG AGCATTGCAA ACACAATAGT CTTGATGGCA 
GAGGTGCAAT TAGATTCCCT GAAACAGAAA GGAGCTATTA AACGGACGCT CTTCCTTGAT 
AACCATCAGG CTCATCGCGT CTTCCCTCTT GTGATAAAAA GGCAGAAATC CCACCAGTGC 
CAGGATTTCA TCGTTTACCT TCGAGATGAA ACTGAATTCC GAGATAAATT ATCTCCAATC 
AACATTAGTT TGAATTACAG TTTGGACGAA TCCACCTTTA AAGAAGGCCT GGAAGTGAAA 
CCAATATTGA ACTACTACAG AGAAAACATT GTTAGTGAAC AGGCTCACAT TCTGGTGGAC 
TGTGGAGAAG ACAATCTGTG TGTTCCTGAC TTGAAGCTGT CGGCTAGACC AGATAAGCAT 
CAGGTAATCA TTGGAGATGA AAATCACCTT ATGCTCATAA TAAATGCAAG AAATGAAGGG 
GAAGGAGCAT ATGAAGCTGA ACTCTTTGTA ATGATACCAG AAGAGGCAGA TTATGTTGGA 
ATCGAACGCA ACAACAAGGG ATTTCGACCA CTGAGCTGTG AGTACAAGAT GGAAAATGTA 
ACCAGGATGG TGGTGTGTGA CCTTGGGAAC CCTATGGTGT CTGGAACAAA TTATTCCCTG 
GGCCTCCGAT TTGCAGTTCC ACGTCTTGAG AAAACAAACA TGAGCATTAA CTTCGATCTC 
CAAATCAGAA GTTCCAACAA GGACAATCCA GACAGCAATT TTGTGAGCCT GCAAATCAAC 
ATCACTGCTG TAGCGCAGGT GGAAATAAGA GGAGTGTCAC ACCCTCCGCA GATTGTTCTG 
CCCATTCATA ACTGGGAACC AGAAGAGGAG CCCCACAAAG AGGAGGAGGT TGGACCATTG 
GTGGAACATA TTTATGAGCT GCACAATATT GGACCAAGTA CCATCAGTGA CACCATCCTG 
GAGGTGGGCT GGCCTTTCTC TGCCCGGGAT GAATTTCTTC TCTATATTTT CCATATTCAA 
ACTCTGGGAC CTCTGCAGTG CCAACCAAAT CCTAATATCA ATCCACAGGA TATAAAGCCT 
GCTGCCTCCC CAGAGGACAC CCCTGAGCTC AGCGCCTTTT TGCGAAACTC TACTATTCCT 
CATCTTGTCA GGAAGAGGGA TGTACATGTG GTCGAATTCC ACAGACAGAG CCCTGCAAAA 
ATACTGAATT GTACAAATAT CGAGTGTTTA CAAATCTCCT GTGCAGTGGG ACGACTCGAA 
GGAGGAGAAA GCGCAGTCCT GAAAGTCAGG TCACGATTAT GGGCCCACAC CTTCCTCCAG 
AGAAAAAATG ATCCCTATGC TCTTGCATCC CTGGTGTCCT TTGAAGTTAA GAAGATGCCT 
TATACAGATC AGCCAGCAAA ACTCCCAGAA GGAAGCATAG TAATTAAGAC ATCAGTTATT 
TGGGCAACTC CGAATGTTTC CTTCTCAATC CCATTATGGG TAATAATACT AGCAATACTT 
CTTGGATTGT TGGTTCTCGC CATTTTAACC TTAGCTTTAT GGAAGTGTGG ATTCTTTGAC 
AGAGCCAGAC CTCCTCAGGA GGACATGACC GACAGGGAAC AGCTGACAAA TGACAAGACC 
CCTGAGGCAT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ITGA8 ( XM_011519752.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011518054.1 Homo sapiens integrin subunit alpha 8 (ITGA8), transcript variant X1, mRNA.

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CloneID	OHu61909
Clone ID Related Accession (Same CDS sequence)	XM_011519752.2
Accession Version	XM_011519752.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2400bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	integrin alpha-8 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000010.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011519752.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTCGCCCG GGGCCAGCCG CGGTCCCCGG GGAAGCCAGG CGCCGCTGAT CGCGCCCCTC 
TGCTGCGCCG CGGCCGCGCT GGGGATGTTG CTGTGGTCCC CCGCCTGTCA GGCGTTCAAC 
CTGGACGTGG AAAAGCTCAC AGTGTACAGC GGCCCCAAGG GCAGCTACTT CGGCTACGCC 
GTGGACTTCC ACATACCCGA CGCCCGCACA GCGAGTGTCT TGGTGGGGGC GCCCAAAGCC 
AACACCAGCC AGCCCGATAT CGTGGAAGGG GGAGCCGTCT ATTACTGTCC TTGGCCCGCG 
GAGGGGTCTG CGCAGTGCAG GCAGATACCG TTTGACACCA CCAACAACAG AAAGATCAGA 
GTTAATGGAA CCAAAGAACC TATCGAGTTC AAATCCAATC AGTGGTTTGG AGCAACAGTG 
AAAGCTCACA AAGGAAAAGT TGTGGCCTGT GCTCCTTTAT ATCACTGGAG AACTCTTAAA 
CCGACACCAG AAAAGGACCC AGTTGGCACC TGCTATGTAG CAATTCAGAA CTTCAGCGCC 
TATGCCGAGT TCTCTCCTTG CCGGAACAGC AATGCTGATC CGGAAGGCCA GGGTTACTGC 
CAAGCAGGAT TTAGTCTGGA TTTTTATAAG AATGGAGACC TTATTGTGGG AGGACCTGGG 
AGTTTCTACT GGCAAGGACA AGTGATCACT GCCAGTGTTG CAGATATCAT TGCAAATTAC 
TCATTCAAGG ATATCCTCAG GAAACTGGCA GGAGAAAAGC AGACGGAAGT GGCTCCAGCT 
TCCTATGATG ACAGTTACCT TGGATACTCA GTTGCTGCTG GGGAGTTTAC TGGGGATTCT 
CAGCAAGAAT TGGTTGCTGG AATTCCAAGA GGAGCACAGA ATTTTGGATA TGTTTCCATC 
ATTAACTCTA CGGATATGAC GTTTATTCAG AATTTCACGG GAGAACAGAT GGCATCTTAT 
TTTGGATATA CCGTTGTCGT ATCAGATGTT AACAGTGATG GACTGGATGA TGTCCTGGTT 
GGGGCACCTC TCTTTATGGA ACGTGAATTT GAGAGCAACC CCAGAGAAGT AGGGCAAATC 
TACCTGTATT TGCAAGTGAG CTCTCTCCTC TTCAGAGACC CCCAGATCCT CACTGGCACC 
GAGACGTTTG GGAGATTCGG TAGTGCTATG GCACACTTAG GAGACCTGAA CCAAGATGGA 
TACAATGACA TTGCCATCGG AGTGCCTTTT GCAGGCAAGG ATCAAAGAGG CAAAGTGCTC 
ATTTATAATG GGAACAAAGA TGGCTTAAAC ACCAAGCCTT CCCAAGTTCT GCAAGGAGTG 
TGGGCCTCAC ATGCTGTCCC TTCCGGATTT GGCTTTACTT TAAGAGGAGA TTCAGACATA 
GACAAGAATG ATTACCCAGA TTTGATTGTG GGTGCATTTG GAACAGGAAA AGTCGCTGTT 
TACAGAGCAA GACCGGTTGT GACTGTAGAT GCCCAGCTTC TGCTGCACCC AATGATTATC 
AATCTTGAAA ATAAAACTTG CCAGGTTCCA GACTCTATGA CATCTGCTGC CTGCTTTTCT 
TTAAGAGTAT GTGCATCTGT CACAGGCCAG AGCATTGCAA ACACAATAGT CTTGATGGCA 
GAGGTGCAAT TAGATTCCCT GAAACAGAAA GGAGCTATTA AACGGACGCT CTTCCTTGAT 
AACCATCAGG CTCATCGCGT CTTCCCTCTT GTGATAAAAA GGCAGAAATC CCACCAGTGC 
CAGGATTTCA TCGTTTACCT TCGAGATGAA ACTGAATTCC GAGATAAATT ATCTCCAATC 
AACATTAGTT TGAATTACAG TTTGGACGAA TCCACCTTTA AAGAAGGCCT GGAAGTGAAA 
CCAATATTGA ACTACTACAG AGAAAACATT GTTAGTGAAC AGGCTCACAT TCTGGTGGAC 
TGTGGAGAAG ACAATCTGTG TGTTCCTGAC TTGAAGCTGT CGGCTAGACC AGATAAGCAT 
CAGGTAATCA TTGGAGATGA AAATCACCTT ATGCTCATAA TAAATGCAAG AAATGAAGGG 
GAAGGAGCAT ATGAAGCTGA ACTCTTTGTA ATGATACCAG AAGAGGCAGA TTATGTTGGA 
ATCGAACGCA ACAACAAGGG ATTTCGACCA CTGAGCTGTG AGTACAAGAT GGAAAATGTA 
ACCAGGATGG TGGTGTGTGA CCTTGGGAAC CCTATGGTGT CTGGAACAAA TTATTCCCTG 
GGCCTCCGAT TTGCAGTTCC ACGTCTTGAG AAAACAAACA TGAGCATTAA CTTCGATCTC 
CAAATCAGAA GTTCCAACAA GGACAATCCA GACAGCAATT TTGTGAGCCT GCAAATCAAC 
ATCACTGCTG TAGCGCAGGT GGAAATAAGA GGACTAGAAC CACCAGTGCA TGATCAATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011518054.1
CDS	559..2958
Translation	MSPGASRGPRGSQAPLIAPLCCAAAALGMLLWSPACQAFNLDVEKLTVYSGPKGSYFGYAVDFHIPDARTASVLVGAPKANTSQPDIVEGGAVYYCPWPAEGSAQCRQIPFDTTNNRKIRVNGTKEPIEFKSNQWFGATVKAHKGKVVACAPLYHWRTLKPTPEKDPVGTCYVAIQNFSAYAEFSPCRNSNADPEGQGYCQAGFSLDFYKNGDLIVGGPGSFYWQGQVITASVADIIANYSFKDILRKLAGEKQTEVAPASYDDSYLGYSVAAGEFTGDSQQELVAGIPRGAQNFGYVSIINSTDMTFIQNFTGEQMASYFGYTVVVSDVNSDGLDDVLVGAPLFMEREFESNPREVGQIYLYLQVSSLLFRDPQILTGTETFGRFGSAMAHLGDLNQDGYNDIAIGVPFAGKDQRGKVLIYNGNKDGLNTKPSQVLQGVWASHAVPSGFGFTLRGDSDIDKNDYPDLIVGAFGTGKVAVYRARPVVTVDAQLLLHPMIINLENKTCQVPDSMTSAACFSLRVCASVTGQSIANTIVLMAEVQLDSLKQKGAIKRTLFLDNHQAHRVFPLVIKRQKSHQCQDFIVYLRDETEFRDKLSPINISLNYSLDESTFKEGLEVKPILNYYRENIVSEQAHILVDCGEDNLCVPDLKLSARPDKHQVIIGDENHLMLIINARNEGEGAYEAELFVMIPEEADYVGIERNNKGFRPLSCEYKMENVTRMVVCDLGNPMVSGTNYSLGLRFAVPRLEKTNMSINFDLQIRSSNKDNPDSNFVSLQINITAVAQVEIRGLEPPVHDQ

Target ORF information:

RefSeq Version	XM_011519752.2
Organism	Homo sapiens(human)
Definition	Homo sapiens integrin subunit alpha 8 (ITGA8), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011519752.2

ORF Insert Sequence:

ATGTCGCCCG GGGCCAGCCG CGGTCCCCGG GGAAGCCAGG CGCCGCTGAT CGCGCCCCTC 
TGCTGCGCCG CGGCCGCGCT GGGGATGTTG CTGTGGTCCC CCGCCTGTCA GGCGTTCAAC 
CTGGACGTGG AAAAGCTCAC AGTGTACAGC GGCCCCAAGG GCAGCTACTT CGGCTACGCC 
GTGGACTTCC ACATACCCGA CGCCCGCACA GCGAGTGTCT TGGTGGGGGC GCCCAAAGCC 
AACACCAGCC AGCCCGATAT CGTGGAAGGG GGAGCCGTCT ATTACTGTCC TTGGCCCGCG 
GAGGGGTCTG CGCAGTGCAG GCAGATACCG TTTGACACCA CCAACAACAG AAAGATCAGA 
GTTAATGGAA CCAAAGAACC TATCGAGTTC AAATCCAATC AGTGGTTTGG AGCAACAGTG 
AAAGCTCACA AAGGAAAAGT TGTGGCCTGT GCTCCTTTAT ATCACTGGAG AACTCTTAAA 
CCGACACCAG AAAAGGACCC AGTTGGCACC TGCTATGTAG CAATTCAGAA CTTCAGCGCC 
TATGCCGAGT TCTCTCCTTG CCGGAACAGC AATGCTGATC CGGAAGGCCA GGGTTACTGC 
CAAGCAGGAT TTAGTCTGGA TTTTTATAAG AATGGAGACC TTATTGTGGG AGGACCTGGG 
AGTTTCTACT GGCAAGGACA AGTGATCACT GCCAGTGTTG CAGATATCAT TGCAAATTAC 
TCATTCAAGG ATATCCTCAG GAAACTGGCA GGAGAAAAGC AGACGGAAGT GGCTCCAGCT 
TCCTATGATG ACAGTTACCT TGGATACTCA GTTGCTGCTG GGGAGTTTAC TGGGGATTCT 
CAGCAAGAAT TGGTTGCTGG AATTCCAAGA GGAGCACAGA ATTTTGGATA TGTTTCCATC 
ATTAACTCTA CGGATATGAC GTTTATTCAG AATTTCACGG GAGAACAGAT GGCATCTTAT 
TTTGGATATA CCGTTGTCGT ATCAGATGTT AACAGTGATG GACTGGATGA TGTCCTGGTT 
GGGGCACCTC TCTTTATGGA ACGTGAATTT GAGAGCAACC CCAGAGAAGT AGGGCAAATC 
TACCTGTATT TGCAAGTGAG CTCTCTCCTC TTCAGAGACC CCCAGATCCT CACTGGCACC 
GAGACGTTTG GGAGATTCGG TAGTGCTATG GCACACTTAG GAGACCTGAA CCAAGATGGA 
TACAATGACA TTGCCATCGG AGTGCCTTTT GCAGGCAAGG ATCAAAGAGG CAAAGTGCTC 
ATTTATAATG GGAACAAAGA TGGCTTAAAC ACCAAGCCTT CCCAAGTTCT GCAAGGAGTG 
TGGGCCTCAC ATGCTGTCCC TTCCGGATTT GGCTTTACTT TAAGAGGAGA TTCAGACATA 
GACAAGAATG ATTACCCAGA TTTGATTGTG GGTGCATTTG GAACAGGAAA AGTCGCTGTT 
TACAGAGCAA GACCGGTTGT GACTGTAGAT GCCCAGCTTC TGCTGCACCC AATGATTATC 
AATCTTGAAA ATAAAACTTG CCAGGTTCCA GACTCTATGA CATCTGCTGC CTGCTTTTCT 
TTAAGAGTAT GTGCATCTGT CACAGGCCAG AGCATTGCAA ACACAATAGT CTTGATGGCA 
GAGGTGCAAT TAGATTCCCT GAAACAGAAA GGAGCTATTA AACGGACGCT CTTCCTTGAT 
AACCATCAGG CTCATCGCGT CTTCCCTCTT GTGATAAAAA GGCAGAAATC CCACCAGTGC 
CAGGATTTCA TCGTTTACCT TCGAGATGAA ACTGAATTCC GAGATAAATT ATCTCCAATC 
AACATTAGTT TGAATTACAG TTTGGACGAA TCCACCTTTA AAGAAGGCCT GGAAGTGAAA 
CCAATATTGA ACTACTACAG AGAAAACATT GTTAGTGAAC AGGCTCACAT TCTGGTGGAC 
TGTGGAGAAG ACAATCTGTG TGTTCCTGAC TTGAAGCTGT CGGCTAGACC AGATAAGCAT 
CAGGTAATCA TTGGAGATGA AAATCACCTT ATGCTCATAA TAAATGCAAG AAATGAAGGG 
GAAGGAGCAT ATGAAGCTGA ACTCTTTGTA ATGATACCAG AAGAGGCAGA TTATGTTGGA 
ATCGAACGCA ACAACAAGGG ATTTCGACCA CTGAGCTGTG AGTACAAGAT GGAAAATGTA 
ACCAGGATGG TGGTGTGTGA CCTTGGGAAC CCTATGGTGT CTGGAACAAA TTATTCCCTG 
GGCCTCCGAT TTGCAGTTCC ACGTCTTGAG AAAACAAACA TGAGCATTAA CTTCGATCTC 
CAAATCAGAA GTTCCAACAA GGACAATCCA GACAGCAATT TTGTGAGCCT GCAAATCAAC 
ATCACTGCTG TAGCGCAGGT GGAAATAAGA GGACTAGAAC CACCAGTGCA TGATCAATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ITGA8 ( NM_001291494.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001278423.1 Homo sapiens integrin subunit alpha 8 (ITGA8), transcript variant 2, mRNA.

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CloneID	OHu16978
Clone ID Related Accession (Same CDS sequence)	NM_001291494.1
Accession Version	NM_001291494.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3147bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-25
Organism	Homo sapiens(human)
Product	integrin alpha-8 isoform 2 preproprotein
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DB237365.1, DC425586.1, AK297740.1, AL590636.12 and BU735798.1. On Apr 17, 2014 this sequence version replaced XM_005252633.1. Transcript Variant: This variant (2) lacks an in-frame exon in the 5' coding region, compared to variant 1. It encodes a shorter protein (isoform 2), compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK297740.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: full length.

ATGTCGCCCG GGGCCAGCCG CGGTCCCCGG GGAAGCCAGG CGCCGCTGAT CGCGCCCCTC 
TGCTGCGCCG CGGCCGCGCT GGGGATGTTG CTGTGGTCCC CCGCCTGTCA GGCGTTCAAC 
CTGGACGTGG AAAAGCTCAC AGTGTACAGC GGCCCCAAGG GCAGCTACTT CGGCTACGCC 
GTGGACTTCC ACATACCCGA CGCCCGCACA GCGAGTGTCT TGGTGGGGGC GCCCAAAGCC 
AACACCAGCC AGCCCGATAT CGTGGAAGGG GGAGCCGTCT ATTACTGTCC TTGGCCCGCG 
GAGGGGTCTG CGCAGTGCAG GCAGATACCG TTTGACACCA CCAACAACAG AAAGATCAGA 
GTTAATGGAA CCAAAGAACC TATCGAGTTC AAATCCAATC AGTGGTTTGG AGCAACAGTG 
AAAGCTCACA AAGGAAAAGT TGTGGCCTGT GCTCCTTTAT ATCACTGGAG AACTCTTAAA 
CCGACACCAG AAAAGGACCC AGTTGGCACC TGCTATGTAG CAATTCAGAA CTTCAGCGCC 
TATGCCGAGT TCTCTCCTTG CCGGAACAGC AATGCTGATC CGGAAGGCCA GGGTTACTGC 
CAAGCAGGAT TTAGTCTGGA TTTTTATAAG AATGGAGACC TTATTGTGGG AGGACCTGGG 
AGTTTCTACT GGCAAGGACA AGTGATCACT GCCAGTGTTG CAGATATCAT TGCAAATTAC 
TCATTCAAGG ATATCCTCAG GAAACTGGCA GGAGAAAAGC AGACGGAAGT GGCTCCAGCT 
TCCTATGATG ACAGTTACCT TGAATTGGTT GCTGGAATTC CAAGAGGAGC ACAGAATTTT 
GGATATGTTT CCATCATTAA CTCTACGGAT ATGACGTTTA TTCAGAATTT CACGGGAGAA 
CAGATGGCAT CTTATTTTGG ATATACCGTT GTCGTATCAG ATGTTAACAG TGATGGACTG 
GATGATGTCC TGGTTGGGGC ACCTCTCTTT ATGGAACGTG AATTTGAGAG CAACCCCAGA 
GAAGTAGGGC AAATCTACCT GTATTTGCAA GTGAGCTCTC TCCTCTTCAG AGACCCCCAG 
ATCCTCACTG GCACCGAGAC GTTTGGGAGA TTCGGTAGTG CTATGGCACA CTTAGGAGAC 
CTGAACCAAG ATGGATACAA TGACATTGCC ATCGGAGTGC CTTTTGCAGG CAAGGATCAA 
AGAGGCAAAG TGCTCATTTA TAATGGGAAC AAAGATGGCT TAAACACCAA GCCTTCCCAA 
GTTCTGCAAG GAGTGTGGGC CTCACATGCT GTCCCTTCCG GATTTGGCTT TACTTTAAGA 
GGAGATTCAG ACATAGACAA GAATGATTAC CCAGATTTGA TTGTGGGTGC ATTTGGAACA 
GGAAAAGTCG CTGTTTACAG AGCAAGACCG GTTGTGACTG TAGATGCCCA GCTTCTGCTG 
CACCCAATGA TTATCAATCT TGAAAATAAA ACTTGCCAGG TTCCAGACTC TATGACATCT 
GCTGCCTGCT TTTCTTTAAG AGTATGTGCA TCTGTCACAG GCCAGAGCAT TGCAAACACA 
ATAGTCTTGA TGGCAGAGGT GCAATTAGAT TCCCTGAAAC AGAAAGGAGC TATTAAACGG 
ACGCTCTTCC TTGATAACCA TCAGGCTCAT CGCGTCTTCC CTCTTGTGAT AAAAAGGCAG 
AAATCCCACC AGTGCCAGGA TTTCATCGTT TACCTTCGAG ATGAAACTGA ATTCCGAGAT 
AAATTATCTC CAATCAACAT TAGTTTGAAT TACAGTTTGG ACGAATCCAC CTTTAAAGAA 
GGCCTGGAAG TGAAACCAAT ATTGAACTAC TACAGAGAAA ACATTGTTAG TGAACAGGCT 
CACATTCTGG TGGACTGTGG AGAAGACAAT CTGTGTGTTC CTGACTTGAA GCTGTCGGCT 
AGACCAGATA AGCATCAGGT AATCATTGGA GATGAAAATC ACCTTATGCT CATAATAAAT 
GCAAGAAATG AAGGGGAAGG AGCATATGAA GCTGAACTCT TTGTAATGAT ACCAGAAGAG 
GCAGATTATG TTGGAATCGA ACGCAACAAC AAGGGATTTC GACCACTGAG CTGTGAGTAC 
AAGATGGAAA ATGTAACCAG GATGGTGGTG TGTGACCTTG GGAACCCTAT GGTGTCTGGA 
ACAAATTATT CCCTGGGCCT CCGATTTGCA GTTCCACGTC TTGAGAAAAC AAACATGAGC 
ATTAACTTCG ATCTCCAAAT CAGAAGTTCC AACAAGGACA ATCCAGACAG CAATTTTGTG 
AGCCTGCAAA TCAACATCAC TGCTGTAGCG CAGGTGGAAA TAAGAGGAGT GTCACACCCT 
CCGCAGATTG TTCTGCCCAT TCATAACTGG GAACCAGAAG AGGAGCCCCA CAAAGAGGAG 
GAGGTTGGAC CATTGGTGGA ACATATTTAT GAGCTGCACA ATATTGGACC AAGTACCATC 
AGTGACACCA TCCTGGAGGT GGGCTGGCCT TTCTCTGCCC GGGATGAATT TCTTCTCTAT 
ATTTTCCATA TTCAAACTCT GGGACCTCTG CAGTGCCAAC CAAATCCTAA TATCAATCCA 
CAGGATATAA AGCCTGCTGC CTCCCCAGAG GACACCCCTG AGCTCAGCGC CTTTTTGCGA 
AACTCTACTA TTCCTCATCT TGTCAGGAAG AGGGATGTAC ATGTGGTCGA ATTCCACAGA 
CAGAGCCCTG CAAAAATACT GAATTGTACA AATATCGAGT GTTTACAAAT CTCCTGTGCA 
GTGGGACGAC TCGAAGGAGG AGAAAGCGCA GTCCTGAAAG TCAGGTCACG ATTATGGGCC 
CACACCTTCC TCCAGAGAAA AAATGATCCC TATGCTCTTG CATCCCTGGT GTCCTTTGAA 
GTTAAGAAGA TGCCTTATAC AGATCAGCCA GCAAAACTCC CAGAAGGAAG CATAGTAATT 
AAGACATCAG TTATTTGGGC AACTCCGAAT GTTTCCTTCT CAATCCCATT ATGGGTAATA 
ATACTAGCAA TACTTCTTGG ATTGTTGGTT CTCGCCATTT TAACCTTAGC TTTATGGAAG 
TGTGGATTCT TTGACAGAGC CAGACCTCCT CAGGAGGACA TGACCGACAG GGAACAGCTG 
ACAAATGACA AGACCCCTGA GGCATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001278423.1
CDS	565..3711
Translation	MSPGASRGPRGSQAPLIAPLCCAAAALGMLLWSPACQAFNLDVEKLTVYSGPKGSYFGYAVDFHIPDARTASVLVGAPKANTSQPDIVEGGAVYYCPWPAEGSAQCRQIPFDTTNNRKIRVNGTKEPIEFKSNQWFGATVKAHKGKVVACAPLYHWRTLKPTPEKDPVGTCYVAIQNFSAYAEFSPCRNSNADPEGQGYCQAGFSLDFYKNGDLIVGGPGSFYWQGQVITASVADIIANYSFKDILRKLAGEKQTEVAPASYDDSYLELVAGIPRGAQNFGYVSIINSTDMTFIQNFTGEQMASYFGYTVVVSDVNSDGLDDVLVGAPLFMEREFESNPREVGQIYLYLQVSSLLFRDPQILTGTETFGRFGSAMAHLGDLNQDGYNDIAIGVPFAGKDQRGKVLIYNGNKDGLNTKPSQVLQGVWASHAVPSGFGFTLRGDSDIDKNDYPDLIVGAFGTGKVAVYRARPVVTVDAQLLLHPMIINLENKTCQVPDSMTSAACFSLRVCASVTGQSIANTIVLMAEVQLDSLKQKGAIKRTLFLDNHQAHRVFPLVIKRQKSHQCQDFIVYLRDETEFRDKLSPINISLNYSLDESTFKEGLEVKPILNYYRENIVSEQAHILVDCGEDNLCVPDLKLSARPDKHQVIIGDENHLMLIINARNEGEGAYEAELFVMIPEEADYVGIERNNKGFRPLSCEYKMENVTRMVVCDLGNPMVSGTNYSLGLRFAVPRLEKTNMSINFDLQIRSSNKDNPDSNFVSLQINITAVAQVEIRGVSHPPQIVLPIHNWEPEEEPHKEEEVGPLVEHIYELHNIGPSTISDTILEVGWPFSARDEFLLYIFHIQTLGPLQCQPNPNINPQDIKPAASPEDTPELSAFLRNSTIPHLVRKRDVHVVEFHRQSPAKILNCTNIECLQISCAVGRLEGGESAVLKVRSRLWAHTFLQRKNDPYALASLVSFEVKKMPYTDQPAKLPEGSIVIKTSVIWATPNVSFSIPLWVIILAILLGLLVLAILTLALWKCGFFDRARPPQEDMTDREQLTNDKTPEA

Target ORF information:

RefSeq Version	NM_001291494.1
Organism	Homo sapiens(human)
Definition	Homo sapiens integrin subunit alpha 8 (ITGA8), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001291494.1

ORF Insert Sequence:

ATGTCGCCCG GGGCCAGCCG CGGTCCCCGG GGAAGCCAGG CGCCGCTGAT CGCGCCCCTC 
TGCTGCGCCG CGGCCGCGCT GGGGATGTTG CTGTGGTCCC CCGCCTGTCA GGCGTTCAAC 
CTGGACGTGG AAAAGCTCAC AGTGTACAGC GGCCCCAAGG GCAGCTACTT CGGCTACGCC 
GTGGACTTCC ACATACCCGA CGCCCGCACA GCGAGTGTCT TGGTGGGGGC GCCCAAAGCC 
AACACCAGCC AGCCCGATAT CGTGGAAGGG GGAGCCGTCT ATTACTGTCC TTGGCCCGCG 
GAGGGGTCTG CGCAGTGCAG GCAGATACCG TTTGACACCA CCAACAACAG AAAGATCAGA 
GTTAATGGAA CCAAAGAACC TATCGAGTTC AAATCCAATC AGTGGTTTGG AGCAACAGTG 
AAAGCTCACA AAGGAAAAGT TGTGGCCTGT GCTCCTTTAT ATCACTGGAG AACTCTTAAA 
CCGACACCAG AAAAGGACCC AGTTGGCACC TGCTATGTAG CAATTCAGAA CTTCAGCGCC 
TATGCCGAGT TCTCTCCTTG CCGGAACAGC AATGCTGATC CGGAAGGCCA GGGTTACTGC 
CAAGCAGGAT TTAGTCTGGA TTTTTATAAG AATGGAGACC TTATTGTGGG AGGACCTGGG 
AGTTTCTACT GGCAAGGACA AGTGATCACT GCCAGTGTTG CAGATATCAT TGCAAATTAC 
TCATTCAAGG ATATCCTCAG GAAACTGGCA GGAGAAAAGC AGACGGAAGT GGCTCCAGCT 
TCCTATGATG ACAGTTACCT TGAATTGGTT GCTGGAATTC CAAGAGGAGC ACAGAATTTT 
GGATATGTTT CCATCATTAA CTCTACGGAT ATGACGTTTA TTCAGAATTT CACGGGAGAA 
CAGATGGCAT CTTATTTTGG ATATACCGTT GTCGTATCAG ATGTTAACAG TGATGGACTG 
GATGATGTCC TGGTTGGGGC ACCTCTCTTT ATGGAACGTG AATTTGAGAG CAACCCCAGA 
GAAGTAGGGC AAATCTACCT GTATTTGCAA GTGAGCTCTC TCCTCTTCAG AGACCCCCAG 
ATCCTCACTG GCACCGAGAC GTTTGGGAGA TTCGGTAGTG CTATGGCACA CTTAGGAGAC 
CTGAACCAAG ATGGATACAA TGACATTGCC ATCGGAGTGC CTTTTGCAGG CAAGGATCAA 
AGAGGCAAAG TGCTCATTTA TAATGGGAAC AAAGATGGCT TAAACACCAA GCCTTCCCAA 
GTTCTGCAAG GAGTGTGGGC CTCACATGCT GTCCCTTCCG GATTTGGCTT TACTTTAAGA 
GGAGATTCAG ACATAGACAA GAATGATTAC CCAGATTTGA TTGTGGGTGC ATTTGGAACA 
GGAAAAGTCG CTGTTTACAG AGCAAGACCG GTTGTGACTG TAGATGCCCA GCTTCTGCTG 
CACCCAATGA TTATCAATCT TGAAAATAAA ACTTGCCAGG TTCCAGACTC TATGACATCT 
GCTGCCTGCT TTTCTTTAAG AGTATGTGCA TCTGTCACAG GCCAGAGCAT TGCAAACACA 
ATAGTCTTGA TGGCAGAGGT GCAATTAGAT TCCCTGAAAC AGAAAGGAGC TATTAAACGG 
ACGCTCTTCC TTGATAACCA TCAGGCTCAT CGCGTCTTCC CTCTTGTGAT AAAAAGGCAG 
AAATCCCACC AGTGCCAGGA TTTCATCGTT TACCTTCGAG ATGAAACTGA ATTCCGAGAT 
AAATTATCTC CAATCAACAT TAGTTTGAAT TACAGTTTGG ACGAATCCAC CTTTAAAGAA 
GGCCTGGAAG TGAAACCAAT ATTGAACTAC TACAGAGAAA ACATTGTTAG TGAACAGGCT 
CACATTCTGG TGGACTGTGG AGAAGACAAT CTGTGTGTTC CTGACTTGAA GCTGTCGGCT 
AGACCAGATA AGCATCAGGT AATCATTGGA GATGAAAATC ACCTTATGCT CATAATAAAT 
GCAAGAAATG AAGGGGAAGG AGCATATGAA GCTGAACTCT TTGTAATGAT ACCAGAAGAG 
GCAGATTATG TTGGAATCGA ACGCAACAAC AAGGGATTTC GACCACTGAG CTGTGAGTAC 
AAGATGGAAA ATGTAACCAG GATGGTGGTG TGTGACCTTG GGAACCCTAT GGTGTCTGGA 
ACAAATTATT CCCTGGGCCT CCGATTTGCA GTTCCACGTC TTGAGAAAAC AAACATGAGC 
ATTAACTTCG ATCTCCAAAT CAGAAGTTCC AACAAGGACA ATCCAGACAG CAATTTTGTG 
AGCCTGCAAA TCAACATCAC TGCTGTAGCG CAGGTGGAAA TAAGAGGAGT GTCACACCCT 
CCGCAGATTG TTCTGCCCAT TCATAACTGG GAACCAGAAG AGGAGCCCCA CAAAGAGGAG 
GAGGTTGGAC CATTGGTGGA ACATATTTAT GAGCTGCACA ATATTGGACC AAGTACCATC 
AGTGACACCA TCCTGGAGGT GGGCTGGCCT TTCTCTGCCC GGGATGAATT TCTTCTCTAT 
ATTTTCCATA TTCAAACTCT GGGACCTCTG CAGTGCCAAC CAAATCCTAA TATCAATCCA 
CAGGATATAA AGCCTGCTGC CTCCCCAGAG GACACCCCTG AGCTCAGCGC CTTTTTGCGA 
AACTCTACTA TTCCTCATCT TGTCAGGAAG AGGGATGTAC ATGTGGTCGA ATTCCACAGA 
CAGAGCCCTG CAAAAATACT GAATTGTACA AATATCGAGT GTTTACAAAT CTCCTGTGCA 
GTGGGACGAC TCGAAGGAGG AGAAAGCGCA GTCCTGAAAG TCAGGTCACG ATTATGGGCC 
CACACCTTCC TCCAGAGAAA AAATGATCCC TATGCTCTTG CATCCCTGGT GTCCTTTGAA 
GTTAAGAAGA TGCCTTATAC AGATCAGCCA GCAAAACTCC CAGAAGGAAG CATAGTAATT 
AAGACATCAG TTATTTGGGC AACTCCGAAT GTTTCCTTCT CAATCCCATT ATGGGTAATA 
ATACTAGCAA TACTTCTTGG ATTGTTGGTT CTCGCCATTT TAACCTTAGC TTTATGGAAG 
TGTGGATTCT TTGACAGAGC CAGACCTCCT CAGGAGGACA TGACCGACAG GGAACAGCTG 
ACAAATGACA AGACCCCTGA GGCATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

ITGA2B and ITGA8 are predictive of prognosis in clear cell renal cell carcinoma patients.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine37(1)253-62(2016 Jan)
Lu X,Wan F,Zhang H,Shi G,Ye D

Mild recessive mutations in six Fraser syndrome-related genes cause isolated congenital anomalies of the kidney and urinary tract.
Journal of the American Society of Nephrology : JASN25(9)1917-22(2014 Sep)
Kohl S,Hwang DY,Dworschak GC,Hilger AC,Saisawat P,Vivante A,Stajic N,Bogdanovic R,Reutter HM,Kehinde EO,Tasic V,Hildebrandt F

Integrin alpha 8 recessive mutations are responsible for bilateral renal agenesis in humans.
American journal of human genetics94(2)288-94(2014 Feb)
Humbert C,Silbermann F,Morar B,Parisot M,Zarhrate M,Masson C,Tores F,Blanchet P,Perez MJ,Petrov Y,Khau Van Kien P,Roume J,Leroy B,Gribouval O,Kalaydjieva L,Heidet L,Salomon R,Antignac C,Benmerah A,Saunier S,Jeanpierre C

Genome-wide association study of chronic periodontitis in a general German population.
Journal of clinical periodontology40(11)977-85(2013 Nov)
Teumer A,Holtfreter B,V?lker U,Petersmann A,Nauck M,Biffar R,V?lzke H,Kroemer HK,Meisel P,Homuth G,Kocher T

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ITGA8 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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