Gene Symbol | CEP19 |
Entrez Gene ID | 84984 |
Full Name | centrosomal protein 19 |
Synonyms | C3orf34,MOSPGF |
General protein information |
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Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Summary | The protein encoded by this gene localizes to centrosomes and primary cilia and co-localizes with a marker for the mother centriole. This gene resides in a region of human chromosome 3 that is linked to morbid obesity. A homozygous knockout of the orthologous gene in mouse resulted in mice with morbid obesity, hyperphagy, glucose intolerance, and insulin resistance. Mutations in this gene cause morbid obesity and spermatogenic failure (MOSPGF). This gene has a pseudogene on human chromosome 2. [provided by RefSeq, Apr 2014]. |
Disorder MIM: | |
Disorder Html: | Morbid obesity and spermatogenic failure, 615703 (3) |