WDR73 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	WDR73
Entrez Gene ID	84942
Full Name	WD repeat domain 73
Synonyms	GAMOS,GAMOS1,HSPC264
General protein information	Preferred Names WD repeat domain 73 Names WD repeat-containing protein 73 FLJ00296 protein
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 15 Map Location: 15q25.2
Summary	The protein encoded by this gene is thought to contain multiple WD40 repeats. WD40 repeats are motifs that contain 40-60 amino acids, and usually end with Trp-Asp (WD). This protein is found in the cytoplasm during interphase, but accumulates at the spindle poles and astral microtubules during mitosis. Reduced expression of this gene results in abnormalities in the size and morphology of the nucleus. Mutations in this gene have been associated with Galloway-Mowat syndrome PMID: 25466283), which is a rare autosomal recessive disorder that affects both the central nervous system and kidneys. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2015].
Disorder MIM:	616144
Disorder Html:	Galloway-Mowat syndrome 1, 251300 (3)

mRNA and Protein(s)

mRNA	Protein	Name
NM_032856.3	NP_116245.2	WD repeat-containing protein 73
NM_032856.5	NP_116245.2	WD repeat-containing protein 73

Pathways from BioSystems

Homologies

Homo sapiens (human)	WDR73	NP_116245.2
Canis lupus familiaris (dog)	WDR73	XP_851953.2
Mus musculus (house mouse)	Wdr73	NP_082302.2
Pan troglodytes (chimpanzee)	WDR73	XP_001162099.1
	LOC696186	XP_001084838.2
Bos taurus (cattle)	WDR73	NP_001071359.1
Rattus norvegicus (Norway rat)	Wdr73	NP_001100995.1
Gallus gallus (chicken)	WDR73	XP_423425.4
Danio rerio (zebrafish)	wdr73	NP_001017646.1
Xenopus tropicalis (tropical clawed frog)	wdr73	XP_002942462.2

Gene Ontology
Bibliography

Related articles in PubMed

WDR73 missense mutation causes infantile onset intellectual disability and cerebellar hypoplasia in a consanguineous family.
Jiang C, Gai N, Zou Y, Zheng Y, Ma R, Wei X, Liang D, Wu L
Clinica chimica acta; international journal of clinical chemistry46424-29(2017 Jan)

WDR73 Mutations Cause Infantile Neurodegeneration and Variable Glomerular Kidney Disease.
Vodopiutz J, Seidl R, Prayer D, Khan MI, Mayr JA, Streubel B, Stei? JO, Hahn A, Csaicsich D, Castro C, Assoum M, M?ller T, Wieczorek D, Mancini GM, Sadowski CE, L?vy N, M?garban? A, Godbole K, Schanze D, Hildebrandt F, Delague V, Janecke AR, Zenker M
Human mutation36(11)1021-8(2015 Nov)

Recessive nephrocerebellar syndrome on the Galloway-Mowat syndrome spectrum is caused by homozygous protein-truncating mutations of WDR73.
Jinks RN, Puffenberger EG, Baple E, Harding B, Crino P, Fogo AB, Wenger O, Xin B, Koehler AE, McGlincy MH, Provencher MM, Smith JD, Tran L, Al Turki S, Chioza BA, Cross H, Harlalka GV, Hurles ME, Maroofian R, Heaps AD, Morton MC, Stempak L, Hildebrandt F, Sadowski CE, Zaritsky J, Campellone K, Morton DH, Wang H, Crosby A, Strauss KA
Brain : a journal of neurology138(Pt 8)2173-90(2015 Aug)

Nonsense mutation in the WDR73 gene is associated with Galloway-Mowat syndrome.
Ben-Omran T, Fahiminiya S, Sorfazlian N, Almuriekhi M, Nawaz Z, Nadaf J, Khadija KA, Zaineddin S, Kamel H, Majewski J, Tropepe V
Journal of medical genetics52(6)381-90(2015 Jun)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

WDR73 as a candidate gene of severe intellectual disability and cerebellar hypoplasia.
Title: WDR73 missense mutation causes infantile onset intellectual disability and cerebellar hypoplasia in a consanguineous family.

We document postnatal onset of CA, a retinopathy, basal ganglia degeneration, and short stature as novel features of WDR73-related disease, and define WDR73-related disease as a new entity of infantile neurodegeneration.
Title: WDR73 Mutations Cause Infantile Neurodegeneration and Variable Glomerular Kidney Disease.

WDR73 interacts with mitotic microtubules to regulate cell cycle progression, proliferation and survival in brain
Title: Recessive nephrocerebellar syndrome on the Galloway-Mowat syndrome spectrum is caused by homozygous protein-truncating mutations of WDR73.

Nonsense mutation in the WDR73 gene is associated with Galloway-Mowat syndrome
Title: Nonsense mutation in the WDR73 gene is associated with Galloway-Mowat syndrome.

WDR73 plays a crucial role in the maintenance of cell architecture and cell survival.
Title: Loss-of-function mutations in WDR73 are responsible for microcephaly and steroid-resistant nephrotic syndrome: Galloway-Mowat syndrome.

The following WDR73 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the WDR73 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu12543	NM_032856.5 Latest version!	Homo sapiens WD repeat domain 73 (WDR73), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
View Old Accession Versions >>
OHu12543	NM_032856.3	Homo sapiens WD repeat domain 73 (WDR73), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

WDR73 ( NM_032856.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_116245.2 Homo sapiens WD repeat domain 73 (WDR73), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu12543
Clone ID Related Accession (Same CDS sequence)	NM_032856.3 , NM_032856.5
Accession Version	NM_032856.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1137bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-05-03
Organism	Homo sapiens(human)
Product	WD repeat-containing protein 73
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BU601517.1, AK225068.1, BM050710.1, BC050648.1, BC014115.2, CX867053.1, AC048382.7 and BM875282.1. This sequence is a reference standard in the RefSeqGene project. On Feb 18, 2015 this sequence version replaced NM_032856.2. Transcript Variant: This variant (1) encodes the protein. ##Evidence-Data-START## Transcript exon combination :: SRR1803611.110292.1, SRR1803614.61502.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGATCCTG GGGACGACTG GCTGGTGGAA TCCTTGCGCT TGTACCAGGA TTTCTATGCA 
TTCGACCTGT CAGGAGCCAC TCGAGTCCTT GAATGGATTG ATGACAAAGG AGTCTTTGTT 
GCTGGCTATG AAAGCCTGAA AAAGAATGAA ATTCTTCATC TGAAATTACC TCTCAGACTT 
TCTGTAAAGG AAAACAAGGG CTTATTCCCA GAAAGAGATT TCAAAGTGCG CCATGGAGGA 
TTTTCAGACA GGTCTATCTT TGATCTAAAG CATGTGCCAC ATACCAGATT GCTGGTTACC 
AGTGGCCTTC CAGGTTGTTA TCTGCAGGTG TGGCAGGTTG CAGAGGACAG TGATGTCATT 
AAAGCTGTCA GCACCATTGC TGTGCATGAG AAAGAGGAGA GTCTCTGGCC TAGGGTGGCC 
GTCTTCTCCA CATTGGCACC CGGAGTCCTC CATGGGGCGA GGCTCCGAAG TCTGCAGGTC 
GTTGATCTGG AGTCCCGGAA GACCACGTAC ACCTCAGATG TCAGTGACAG TGAGGAGCTG 
AGTAGCCTGC AGGTCCTAGA TGCAGACACC TTTGCCTTCT GCTGTGCTTC AGGCCGGCTG 
GGGCTTGTTG ACACCCGGCA GAAGTGGGCA CCGTTGGAGA ATCGCAGCCC TGGCCCTGGG 
TCTGGTGGAG AGAGATGGTG TGCTGAAGTT GGGAGCTGGG GCCAGGGCCC TGGGCCCAGC 
ATTGCCAGCC TTGGCTCAGA TGGGCGTCTT TGTCTTCTTG ACCCCCGGGA TCTCTGCCAT 
CCTGTGAGCT CAGTCCAGTG CCCAGTATCC GTACCTAGCC CTGACCCAGA GCTGCTGCGA 
GTGACTTGGG CCCCAGGCCT GAAGAATTGC TTGGCCATCT CAGGTTTTGA TGGTACAGTC 
CAGGTCTATG ATGCCACATC TTGGGATGGA ACACGGAGCC AAGATGGAAC ACGGAGCCAA 
GTAGAACCTC TCTTCACTCA CAGAGGTCAC ATCTTCCTAG ATGGAAATGG GATGGACCCT 
GCTCCTTTGG TCACCACCCA CACCTGGCAT CCCTGCAGAC CAAGGACTTT GTTATCAGCA 
ACAAATGATG CCTCTCTGCA TGTGTGGGAC TGGGTGGACC TTTGTGCCCC CCGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_116245.2
CDS	70..1206
Translation	MDPGDDWLVESLRLYQDFYAFDLSGATRVLEWIDDKGVFVAGYESLKKNEILHLKLPLRLSVKENKGLFPERDFKVRHGGFSDRSIFDLKHVPHTRLLVTSGLPGCYLQVWQVAEDSDVIKAVSTIAVHEKEESLWPRVAVFSTLAPGVLHGARLRSLQVVDLESRKTTYTSDVSDSEELSSLQVLDADTFAFCCASGRLGLVDTRQKWAPLENRSPGPGSGGERWCAEVGSWGQGPGPSIASLGSDGRLCLLDPRDLCHPVSSVQCPVSVPSPDPELLRVTWAPGLKNCLAISGFDGTVQVYDATSWDGTRSQDGTRSQVEPLFTHRGHIFLDGNGMDPAPLVTTHTWHPCRPRTLLSATNDASLHVWDWVDLCAPR

Target ORF information:

RefSeq Version	NM_032856.3
Organism	Homo sapiens(human)
Definition	Homo sapiens WD repeat domain 73 (WDR73), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_032856.3

ORF Insert Sequence:

ATGGATCCTG GGGACGACTG GCTGGTGGAA TCCTTGCGCT TGTACCAGGA TTTCTATGCA 
TTCGACCTGT CAGGAGCCAC TCGAGTCCTT GAATGGATTG ATGACAAAGG AGTCTTTGTT 
GCTGGCTATG AAAGCCTGAA AAAGAATGAA ATTCTTCATC TGAAATTACC TCTCAGACTT 
TCTGTAAAGG AAAACAAGGG CTTATTCCCA GAAAGAGATT TCAAAGTGCG CCATGGAGGA 
TTTTCAGACA GGTCTATCTT TGATCTAAAG CATGTGCCAC ATACCAGATT GCTGGTTACC 
AGTGGCCTTC CAGGTTGTTA TCTGCAGGTG TGGCAGGTTG CAGAGGACAG TGATGTCATT 
AAAGCTGTCA GCACCATTGC TGTGCATGAG AAAGAGGAGA GTCTCTGGCC TAGGGTGGCC 
GTCTTCTCCA CATTGGCACC CGGAGTCCTC CATGGGGCGA GGCTCCGAAG TCTGCAGGTC 
GTTGATCTGG AGTCCCGGAA GACCACGTAC ACCTCAGATG TCAGTGACAG TGAGGAGCTG 
AGTAGCCTGC AGGTCCTAGA TGCAGACACC TTTGCCTTCT GCTGTGCTTC AGGCCGGCTG 
GGGCTTGTTG ACACCCGGCA GAAGTGGGCA CCGTTGGAGA ATCGCAGCCC TGGCCCTGGG 
TCTGGTGGAG AGAGATGGTG TGCTGAAGTT GGGAGCTGGG GCCAGGGCCC TGGGCCCAGC 
ATTGCCAGCC TTGGCTCAGA TGGGCGTCTT TGTCTTCTTG ACCCCCGGGA TCTCTGCCAT 
CCTGTGAGCT CAGTCCAGTG CCCAGTATCC GTACCTAGCC CTGACCCAGA GCTGCTGCGA 
GTGACTTGGG CCCCAGGCCT GAAGAATTGC TTGGCCATCT CAGGTTTTGA TGGTACAGTC 
CAGGTCTATG ATGCCACATC TTGGGATGGA ACACGGAGCC AAGATGGAAC ACGGAGCCAA 
GTAGAACCTC TCTTCACTCA CAGAGGTCAC ATCTTCCTAG ATGGAAATGG GATGGACCCT 
GCTCCTTTGG TCACCACCCA CACCTGGCAT CCCTGCAGAC CAAGGACTTT GTTATCAGCA 
ACAAATGATG CCTCTCTGCA TGTGTGGGAC TGGGTGGACC TTTGTGCCCC CCGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

WDR73 ( NM_032856.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_116245.2 Homo sapiens WD repeat domain 73 (WDR73), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu12543
Clone ID Related Accession (Same CDS sequence)	NM_032856.3 , NM_032856.5
Accession Version	NM_032856.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1137bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-19
Organism	Homo sapiens(human)
Product	WD repeat-containing protein 73
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC048382.7. On Nov 30, 2019 this sequence version replaced NM_032856.4. Transcript Variant: This variant (1) encodes the protein. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: AK225068.1, AK027794.1 [ECO:0000332] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGATCCTG GGGACGACTG GCTGGTGGAA TCCTTGCGCT TGTACCAGGA TTTCTATGCA 
TTCGACCTGT CAGGAGCCAC TCGAGTCCTT GAATGGATTG ATGACAAAGG AGTCTTTGTT 
GCTGGCTATG AAAGCCTGAA AAAGAATGAA ATTCTTCATC TGAAATTACC TCTCAGACTT 
TCTGTAAAGG AAAACAAGGG CTTATTCCCA GAAAGAGATT TCAAAGTGCG CCATGGAGGA 
TTTTCAGACA GGTCTATCTT TGATCTAAAG CATGTGCCAC ATACCAGATT GCTGGTTACC 
AGTGGCCTTC CAGGTTGTTA TCTGCAGGTG TGGCAGGTTG CAGAGGACAG TGATGTCATT 
AAAGCTGTCA GCACCATTGC TGTGCATGAG AAAGAGGAGA GTCTCTGGCC TAGGGTGGCC 
GTCTTCTCCA CATTGGCACC CGGAGTCCTC CATGGGGCGA GGCTCCGAAG TCTGCAGGTC 
GTTGATCTGG AGTCCCGGAA GACCACGTAC ACCTCAGATG TCAGTGACAG TGAGGAGCTG 
AGTAGCCTGC AGGTCCTAGA TGCAGACACC TTTGCCTTCT GCTGTGCTTC AGGCCGGCTG 
GGGCTTGTTG ACACCCGGCA GAAGTGGGCA CCGTTGGAGA ATCGCAGCCC TGGCCCTGGG 
TCTGGTGGAG AGAGATGGTG TGCTGAAGTT GGGAGCTGGG GCCAGGGCCC TGGGCCCAGC 
ATTGCCAGCC TTGGCTCAGA TGGGCGTCTT TGTCTTCTTG ACCCCCGGGA TCTCTGCCAT 
CCTGTGAGCT CAGTCCAGTG CCCAGTATCC GTACCTAGCC CTGACCCAGA GCTGCTGCGA 
GTGACTTGGG CCCCAGGCCT GAAGAATTGC TTGGCCATCT CAGGTTTTGA TGGTACAGTC 
CAGGTCTATG ATGCCACATC TTGGGATGGA ACACGGAGCC AAGATGGAAC ACGGAGCCAA 
GTAGAACCTC TCTTCACTCA CAGAGGTCAC ATCTTCCTAG ATGGAAATGG GATGGACCCT 
GCTCCTTTGG TCACCACCCA CACCTGGCAT CCCTGCAGAC CAAGGACTTT GTTATCAGCA 
ACAAATGATG CCTCTCTGCA TGTGTGGGAC TGGGTGGACC TTTGTGCCCC CCGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_116245.2
CDS	10..1146
Translation	MDPGDDWLVESLRLYQDFYAFDLSGATRVLEWIDDKGVFVAGYESLKKNEILHLKLPLRLSVKENKGLFPERDFKVRHGGFSDRSIFDLKHVPHTRLLVTSGLPGCYLQVWQVAEDSDVIKAVSTIAVHEKEESLWPRVAVFSTLAPGVLHGARLRSLQVVDLESRKTTYTSDVSDSEELSSLQVLDADTFAFCCASGRLGLVDTRQKWAPLENRSPGPGSGGERWCAEVGSWGQGPGPSIASLGSDGRLCLLDPRDLCHPVSSVQCPVSVPSPDPELLRVTWAPGLKNCLAISGFDGTVQVYDATSWDGTRSQDGTRSQVEPLFTHRGHIFLDGNGMDPAPLVTTHTWHPCRPRTLLSATNDASLHVWDWVDLCAPR

Target ORF information:

RefSeq Version	NM_032856.5
Organism	Homo sapiens(human)
Definition	Homo sapiens WD repeat domain 73 (WDR73), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_032856.5

ORF Insert Sequence:

ATGGATCCTG GGGACGACTG GCTGGTGGAA TCCTTGCGCT TGTACCAGGA TTTCTATGCA 
TTCGACCTGT CAGGAGCCAC TCGAGTCCTT GAATGGATTG ATGACAAAGG AGTCTTTGTT 
GCTGGCTATG AAAGCCTGAA AAAGAATGAA ATTCTTCATC TGAAATTACC TCTCAGACTT 
TCTGTAAAGG AAAACAAGGG CTTATTCCCA GAAAGAGATT TCAAAGTGCG CCATGGAGGA 
TTTTCAGACA GGTCTATCTT TGATCTAAAG CATGTGCCAC ATACCAGATT GCTGGTTACC 
AGTGGCCTTC CAGGTTGTTA TCTGCAGGTG TGGCAGGTTG CAGAGGACAG TGATGTCATT 
AAAGCTGTCA GCACCATTGC TGTGCATGAG AAAGAGGAGA GTCTCTGGCC TAGGGTGGCC 
GTCTTCTCCA CATTGGCACC CGGAGTCCTC CATGGGGCGA GGCTCCGAAG TCTGCAGGTC 
GTTGATCTGG AGTCCCGGAA GACCACGTAC ACCTCAGATG TCAGTGACAG TGAGGAGCTG 
AGTAGCCTGC AGGTCCTAGA TGCAGACACC TTTGCCTTCT GCTGTGCTTC AGGCCGGCTG 
GGGCTTGTTG ACACCCGGCA GAAGTGGGCA CCGTTGGAGA ATCGCAGCCC TGGCCCTGGG 
TCTGGTGGAG AGAGATGGTG TGCTGAAGTT GGGAGCTGGG GCCAGGGCCC TGGGCCCAGC 
ATTGCCAGCC TTGGCTCAGA TGGGCGTCTT TGTCTTCTTG ACCCCCGGGA TCTCTGCCAT 
CCTGTGAGCT CAGTCCAGTG CCCAGTATCC GTACCTAGCC CTGACCCAGA GCTGCTGCGA 
GTGACTTGGG CCCCAGGCCT GAAGAATTGC TTGGCCATCT CAGGTTTTGA TGGTACAGTC 
CAGGTCTATG ATGCCACATC TTGGGATGGA ACACGGAGCC AAGATGGAAC ACGGAGCCAA 
GTAGAACCTC TCTTCACTCA CAGAGGTCAC ATCTTCCTAG ATGGAAATGG GATGGACCCT 
GCTCCTTTGG TCACCACCCA CACCTGGCAT CCCTGCAGAC CAAGGACTTT GTTATCAGCA 
ACAAATGATG CCTCTCTGCA TGTGTGGGAC TGGGTGGACC TTTGTGCCCC CCGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

WDR73 missense mutation causes infantile onset intellectual disability and cerebellar hypoplasia in a consanguineous family.
Clinica chimica acta; international journal of clinical chemistry46424-29(2017 Jan)
Jiang C,Gai N,Zou Y,Zheng Y,Ma R,Wei X,Liang D,Wu L

WDR73 Mutations Cause Infantile Neurodegeneration and Variable Glomerular Kidney Disease.
Human mutation36(11)1021-8(2015 Nov)
Vodopiutz J,Seidl R,Prayer D,Khan MI,Mayr JA,Streubel B,Stei? JO,Hahn A,Csaicsich D,Castro C,Assoum M,M?ller T,Wieczorek D,Mancini GM,Sadowski CE,L?vy N,M?garban? A,Godbole K,Schanze D,Hildebrandt F,Delague V,Janecke AR,Zenker M

Recessive nephrocerebellar syndrome on the Galloway-Mowat syndrome spectrum is caused by homozygous protein-truncating mutations of WDR73.
Brain : a journal of neurology138(Pt 8)2173-90(2015 Aug)
Jinks RN,Puffenberger EG,Baple E,Harding B,Crino P,Fogo AB,Wenger O,Xin B,Koehler AE,McGlincy MH,Provencher MM,Smith JD,Tran L,Al Turki S,Chioza BA,Cross H,Harlalka GV,Hurles ME,Maroofian R,Heaps AD,Morton MC,Stempak L,Hildebrandt F,Sadowski CE,Zaritsky J,Campellone K,Morton DH,Wang H,Crosby A,Strauss KA

Nonsense mutation in the WDR73 gene is associated with Galloway-Mowat syndrome.
Journal of medical genetics52(6)381-90(2015 Jun)
Ben-Omran T,Fahiminiya S,Sorfazlian N,Almuriekhi M,Nawaz Z,Nadaf J,Khadija KA,Zaineddin S,Kamel H,Majewski J,Tropepe V

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WDR73 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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