UTP4 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	UTP4
Entrez Gene ID	84916
Full Name	UTP4, small subunit processome component
Synonyms	CIRH1A,CIRHIN,NAIC,TEX292
General protein information	Preferred Names UTP4, small subunit processome component Names U3 small nucleolar RNA-associated protein 4 homolog UTP4 small subunit (SSU) processome component UTP4, small subunit (SSU) processome component, homolog cirrhosis, autosomal recessive 1A (cirhin) testis expressed gene 292
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 16 Map Location: 16q22.1
Summary	This gene encodes a WD40-repeat-containing protein that is localized to the nucleolus. Mutation of this gene causes North American Indian childhood cirrhosis, a severe intrahepatic cholestasis that results in transient neonatal jaundice, and progresses to periportal fibrosis and cirrhosis in childhood and adolescence. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016].
Disorder MIM:	607456

mRNA and Protein(s)

mRNA	Protein	Name
XM_005256205.3	XP_005256262.2	U3 small nucleolar RNA-associated protein 4 homolog isoform X1
NM_032830.2	NP_116219.2	U3 small nucleolar RNA-associated protein 4 homolog isoform 1
NM_001318391.1	NP_001305320.1	U3 small nucleolar RNA-associated protein 4 homolog isoform 2
NM_032830.3	NP_116219.2	U3 small nucleolar RNA-associated protein 4 homolog isoform 1

Pathways from BioSystems

Homologies

Homo sapiens (human)	CIRH1A	NP_116219.2
Danio rerio (zebrafish)	cirh1a	NP_998447.1
Arabidopsis thaliana (thale cress)	AT4G07410	NP_567317.2
Rattus norvegicus (Norway rat)	Cirh1a	NP_001009640.1
Oryza sativa (rice)	Os03g0735100	NP_001051185.2
	CIRH1A	XP_001093408.2
Canis lupus familiaris (dog)	CIRH1A	XP_546858.3
Bos taurus (cattle)	CIRH1A	NP_001192601.1
Saccharomyces cerevisiae (baker's yeast)	UTP4	NP_010611.3
Kluyveromyces lactis	KLLA0D13222g	XP_453652.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP006092	XP_316150.4
Eremothecium gossypii	AGOS_AGR367C	NP_987033.2
Schizosaccharomyces pombe (fission yeast)	utp4	NP_596540.1
Arabidopsis thaliana (thale cress)	AT1G27470	NP_174067.2
Xenopus tropicalis (tropical clawed frog)	cirh1a	NP_001039163.1
Pan troglodytes (chimpanzee)	CIRH1A	XP_511062.3
Mus musculus (house mouse)	Cirh1a	NP_035704.2
Gallus gallus (chicken)	CIRH1A	XP_004944391.1
Drosophila melanogaster (fruit fly)	l(3)72Dn	NP_001261930.1

Gene Ontology
Bibliography

Related articles in PubMed

Architecture of the human interactome defines protein communities and disease networks.
Huttlin EL, Bruckner RJ, Paulo JA, Cannon JR, Ting L, Baltier K, Colby G, Gebreab F, Gygi MP, Parzen H, Szpyt J, Tam S, Zarraga G, Pontano-Vaites L, Swarup S, White AE, Schweppe DK, Rad R, Erickson BK, Obar RA, Guruharsha KG, Li K, Artavanis-Tsakonas S, Gygi SP, Harper JW
Nature545(7655)505-509(2017 05)

CIRH1A augments the proliferation of RKO colorectal cancer cells.
Guo F, Chen JJ, Tang WJ
Oncology reports37(4)2375-2381(2017 Apr)

Interaction, mobility, and phosphorylation of human orthologues of WD repeat-containing components of the yeast SSU processome t-UTP sub-complex.
Sato M, Araki N, Kumeta M, Takeyasu K, Taguchi Y, Asai T, Furukawa K, Horigome T
Biochemistry and cell biology = Biochimie et biologie cellulaire91(6)466-75(2013 Dec)

Insights into RNA biology from an atlas of mammalian mRNA-binding proteins.
Castello A, Fischer B, Eichelbaum K, Horos R, Beckmann BM, Strein C, Davey NE, Humphreys DT, Preiss T, Steinmetz LM, Krijgsveld J, Hentze MW
Cell149(6)1393-406(2012 Jun)

NOL11, implicated in the pathogenesis of North American Indian childhood cirrhosis, is required for pre-rRNA transcription and processing.
Freed EF, Prieto JL, McCann KL, McStay B, Baserga SJ
PLoS genetics8(8)e1002892(2012)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Results show that CIRH1A was highly expressed in carcinoma samples and colorectal cancer cells and suggest that CIRH1A plays a critical role in the proliferation, cell cycle distribution, and apoptosis of human malignant colorectal cells.
Title: CIRH1A augments the proliferation of RKO colorectal cancer cells.

Cirhin is a transcriptional regulatory factor of this NF-kappaB sequence and could be a participant in the regulation of other genes with NF-kappaB responsive elements.
Title: Cirhin up-regulates a canonical NF-kappaB element through strong interaction with Cirip/HIVEP1.

Cirhin is a nucleolar protein and the R565W mutation, for which all North American Indian childhood cirrhosis patients are homozygous, has no effect on subcellular localization.
Title: Nucleolar localization of cirhin, the protein mutated in North American Indian childhood cirrhosis.

A missense mutation (R565W) in cirhin (FLJ14728) in North American Indian childhood cirrhosis
Title: A missense mutation (R565W) in cirhin (FLJ14728) in North American Indian childhood cirrhosis.

The following UTP4 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the UTP4 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu18371	NM_032830.3 Latest version!	Homo sapiens UTP4 small subunit processome component (UTP4), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
OHu49549	NM_001318391.1 Latest version!	Homo sapiens UTP4 small subunit processome component (UTP4), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$307.30 $439.00
OHu73851	XM_005256205.3 Latest version!	Homo sapiens UTP4 small subunit processome component (UTP4), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
View Old Accession Versions >>
OHu18371	NM_032830.2	Homo sapiens UTP4, small subunit processome component (UTP4), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
Hide Old Accession Versions >>

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***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

UTP4 ( NM_032830.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_116219.2 Homo sapiens UTP4, small subunit processome component (UTP4), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu18371
Clone ID Related Accession (Same CDS sequence)	NM_032830.2 , NM_032830.3
Accession Version	NM_032830.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2061bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-01
Organism	Homo sapiens(human)
Product	U3 small nucleolar RNA-associated protein 4 homolog isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA277545.1, BC009348.2 and CA430627.1. This sequence is a reference standard in the RefSeqGene project. On Apr 29, 2008 this sequence version replaced NM_032830.1. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK074795.1, SRR1660809.204959.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGGTGAAT TTAAGGTCCA TCGAGTACGT TTCTTTAATT ATGTTCCATC AGGAATCCGC 
TGTGTGGCTT ACAATAACCA GTCAAACAGA TTGGCTGTTT CACGAACAGA TGGCACTGTG 
GAAATTTATA ACTTGTCAGC AAACTACTTT CAGGAGAAAT TTTTCCCAGG TCATGAGTCT 
CGGGCTACAG AAGCTTTGTG CTGGGCAGAA GGACAGCGAC TCTTTAGTGC TGGGCTCAAT 
GGCGAGATTA TGGAGTATGA TTTACAGGCG TTAAACATCA AGTATGCTAT GGATGCCTTT 
GGAGGACCTA TTTGGAGCAT GGCTGCCAGC CCCAGTGGCT CTCAACTTTT GGTTGGTTGT 
GAAGATGGAT CTGTGAAACT ATTTCAAATT ACCCCAGACA AAATCCAGTT TGAAAGAAAT 
TTTGATCGGC AGAAAAGTCG CATCCTGAGT CTCAGCTGGC ATCCCTCTGG TACCCACATT 
GCAGCTGGTT CCATAGACTA CATTAGTGTG TTTGATGTCA AATCAGGCAG CGCTGTTCAT 
AAGATGATTG TGGACAGGCA GTATATGGGC GTGTCTAAGC GGAAGTGCAT CGTGTGGGGT 
GTCGCCTTCT TGTCCGATGG CACTATCATA AGTGTGGACT CTGCTGGGAA GGTGCAGTTC 
TGGGACTCAG CCACTGGGAC GCTTGTGAAG AGCCATCTCA TCGCTAATGC TGACGTGCAG 
TCCATTGCTG TAGCTGACCA AGAAGACAGT TTCGTGGTGG GCACAGCCGA GGGAACAGTC 
TTCCATTTTC AGCTGGTCCC TGTGACATCT AACAGCAGTG AGAAGCAGTG GGTGCGGACA 
AAACCGTTCC AGCATCACAC TCATGACGTG CGCACTGTGG CCCACAGCCC AACAGCGCTG 
ATATCTGGAG GCACTGACAC CCACTTAGTC TTTCGTCCTC TCATGGAGAA GGTGGAAGTA 
AAGAATTACG ATGCCGCTCT CCGAAAAATC ACCTTTCCCC ACCGATGTCT CATCTCCTGT 
TCTAAAAAGA GGCAGCTTCT CCTCTTCCAG TTTGCTCATC ACTTAGAACT TTGGCGACTG 
GGATCCACAG TTGCAACAGG CAAGAATGGG GATACTCTTC CACTCTCTAA AAATGCAGAT 
CATTTACTGC ACCTAAAGAC AAAGGGTCCT GAGAACATTA TCTGTAGCTG TATCTCCCCA 
TGTGGAAGTT GGATAGCCTA TTCTACAGTT TCTCGGTTTT TTCTCTATCG GCTGAATTAT 
GAACATGACA ACATAAGCCT CAAAAGGGTT TCCAAAATGC CAGCATTCCT TCGCTCTGCC 
CTTCAGATTT TGTTTTCTGA AGATTCAACA AAGCTCTTTG TAGCATCAAA TCAAGGAGCT 
CTGCATATTG TTCAGCTGTC AGGAGGAAGC TTCAAGCACC TGCATGCTTT CCAGCCTCAG 
TCAGGAACAG TGGAGGCCAT GTGTCTTTTG GCAGTCAGTC CAGATGGGAA TTGGCTAGCT 
GCATCAGGTA CCAGTGCTGG AGTCCATGTC TACAACGTAA AACAGCTAAA GCTTCACTGC 
ACGGTGCCTG CTTACAATTT CCCAGTGACT GCTATGGCTA TTGCCCCCAA TACCAACAAC 
CTTGTCATCG CTCATTCGGA CCAGCAGGTA TTTGAGTACA GCATCCCAGA CAAACAGTAT 
ACAGATTGGA GCCGGACTGT CCAGAAGCAG GGCTTTCACC ACCTTTGGCT CCAAAGGGAT 
ACTCCTATCA CACACATCAG TTTTCATCCC AAGAGACCGA TGCACATCCT TCTCCATGAT 
GCCTACATGT TCTGCATCAT TGACAAGTCA TTGCCCCTTC CAAATGACAA AACCTTACTC 
TACAATCCAT TTCCTCCCAC GAATGAATCA GATGTCATCC GGAGGCGCAC AGCTCATGCT 
TTTAAAATTT CTAAGATATA TAAGCCTCTA CTCTTCATGG ATCTTTTGGA TGAAAGAACA 
CTCGTGGCAG TAGAACGGCC TCTGGATGAC ATCATTGCTC AGCTCCCACC ACCCATTAAA 
AAGAAGAAAT TTGGAACCTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_116219.2
CDS	97..2157
Translation	MGEFKVHRVRFFNYVPSGIRCVAYNNQSNRLAVSRTDGTVEIYNLSANYFQEKFFPGHESRATEALCWAEGQRLFSAGLNGEIMEYDLQALNIKYAMDAFGGPIWSMAASPSGSQLLVGCEDGSVKLFQITPDKIQFERNFDRQKSRILSLSWHPSGTHIAAGSIDYISVFDVKSGSAVHKMIVDRQYMGVSKRKCIVWGVAFLSDGTIISVDSAGKVQFWDSATGTLVKSHLIANADVQSIAVADQEDSFVVGTAEGTVFHFQLVPVTSNSSEKQWVRTKPFQHHTHDVRTVAHSPTALISGGTDTHLVFRPLMEKVEVKNYDAALRKITFPHRCLISCSKKRQLLLFQFAHHLELWRLGSTVATGKNGDTLPLSKNADHLLHLKTKGPENIICSCISPCGSWIAYSTVSRFFLYRLNYEHDNISLKRVSKMPAFLRSALQILFSEDSTKLFVASNQGALHIVQLSGGSFKHLHAFQPQSGTVEAMCLLAVSPDGNWLAASGTSAGVHVYNVKQLKLHCTVPAYNFPVTAMAIAPNTNNLVIAHSDQQVFEYSIPDKQYTDWSRTVQKQGFHHLWLQRDTPITHISFHPKRPMHILLHDAYMFCIIDKSLPLPNDKTLLYNPFPPTNESDVIRRRTAHAFKISKIYKPLLFMDLLDERTLVAVERPLDDIIAQLPPPIKKKKFGT

Target ORF information:

RefSeq Version	NM_032830.2
Organism	Homo sapiens(human)
Definition	Homo sapiens UTP4, small subunit processome component (UTP4), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_032830.2

ORF Insert Sequence:

ATGGGTGAAT TTAAGGTCCA TCGAGTACGT TTCTTTAATT ATGTTCCATC AGGAATCCGC 
TGTGTGGCTT ACAATAACCA GTCAAACAGA TTGGCTGTTT CACGAACAGA TGGCACTGTG 
GAAATTTATA ACTTGTCAGC AAACTACTTT CAGGAGAAAT TTTTCCCAGG TCATGAGTCT 
CGGGCTACAG AAGCTTTGTG CTGGGCAGAA GGACAGCGAC TCTTTAGTGC TGGGCTCAAT 
GGCGAGATTA TGGAGTATGA TTTACAGGCG TTAAACATCA AGTATGCTAT GGATGCCTTT 
GGAGGACCTA TTTGGAGCAT GGCTGCCAGC CCCAGTGGCT CTCAACTTTT GGTTGGTTGT 
GAAGATGGAT CTGTGAAACT ATTTCAAATT ACCCCAGACA AAATCCAGTT TGAAAGAAAT 
TTTGATCGGC AGAAAAGTCG CATCCTGAGT CTCAGCTGGC ATCCCTCTGG TACCCACATT 
GCAGCTGGTT CCATAGACTA CATTAGTGTG TTTGATGTCA AATCAGGCAG CGCTGTTCAT 
AAGATGATTG TGGACAGGCA GTATATGGGC GTGTCTAAGC GGAAGTGCAT CGTGTGGGGT 
GTCGCCTTCT TGTCCGATGG CACTATCATA AGTGTGGACT CTGCTGGGAA GGTGCAGTTC 
TGGGACTCAG CCACTGGGAC GCTTGTGAAG AGCCATCTCA TCGCTAATGC TGACGTGCAG 
TCCATTGCTG TAGCTGACCA AGAAGACAGT TTCGTGGTGG GCACAGCCGA GGGAACAGTC 
TTCCATTTTC AGCTGGTCCC TGTGACATCT AACAGCAGTG AGAAGCAGTG GGTGCGGACA 
AAACCGTTCC AGCATCACAC TCATGACGTG CGCACTGTGG CCCACAGCCC AACAGCGCTG 
ATATCTGGAG GCACTGACAC CCACTTAGTC TTTCGTCCTC TCATGGAGAA GGTGGAAGTA 
AAGAATTACG ATGCCGCTCT CCGAAAAATC ACCTTTCCCC ACCGATGTCT CATCTCCTGT 
TCTAAAAAGA GGCAGCTTCT CCTCTTCCAG TTTGCTCATC ACTTAGAACT TTGGCGACTG 
GGATCCACAG TTGCAACAGG CAAGAATGGG GATACTCTTC CACTCTCTAA AAATGCAGAT 
CATTTACTGC ACCTAAAGAC AAAGGGTCCT GAGAACATTA TCTGTAGCTG TATCTCCCCA 
TGTGGAAGTT GGATAGCCTA TTCTACAGTT TCTCGGTTTT TTCTCTATCG GCTGAATTAT 
GAACATGACA ACATAAGCCT CAAAAGGGTT TCCAAAATGC CAGCATTCCT TCGCTCTGCC 
CTTCAGATTT TGTTTTCTGA AGATTCAACA AAGCTCTTTG TAGCATCAAA TCAAGGAGCT 
CTGCATATTG TTCAGCTGTC AGGAGGAAGC TTCAAGCACC TGCATGCTTT CCAGCCTCAG 
TCAGGAACAG TGGAGGCCAT GTGTCTTTTG GCAGTCAGTC CAGATGGGAA TTGGCTAGCT 
GCATCAGGTA CCAGTGCTGG AGTCCATGTC TACAACGTAA AACAGCTAAA GCTTCACTGC 
ACGGTGCCTG CTTACAATTT CCCAGTGACT GCTATGGCTA TTGCCCCCAA TACCAACAAC 
CTTGTCATCG CTCATTCGGA CCAGCAGGTA TTTGAGTACA GCATCCCAGA CAAACAGTAT 
ACAGATTGGA GCCGGACTGT CCAGAAGCAG GGCTTTCACC ACCTTTGGCT CCAAAGGGAT 
ACTCCTATCA CACACATCAG TTTTCATCCC AAGAGACCGA TGCACATCCT TCTCCATGAT 
GCCTACATGT TCTGCATCAT TGACAAGTCA TTGCCCCTTC CAAATGACAA AACCTTACTC 
TACAATCCAT TTCCTCCCAC GAATGAATCA GATGTCATCC GGAGGCGCAC AGCTCATGCT 
TTTAAAATTT CTAAGATATA TAAGCCTCTA CTCTTCATGG ATCTTTTGGA TGAAAGAACA 
CTCGTGGCAG TAGAACGGCC TCTGGATGAC ATCATTGCTC AGCTCCCACC ACCCATTAAA 
AAGAAGAAAT TTGGAACCTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

UTP4 ( NM_032830.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_116219.2 Homo sapiens UTP4 small subunit processome component (UTP4), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu18371
Clone ID Related Accession (Same CDS sequence)	NM_032830.2 , NM_032830.3
Accession Version	NM_032830.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2061bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-09
Organism	Homo sapiens(human)
Product	U3 small nucleolar RNA-associated protein 4 homolog isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA277545.1 and BC009348.2. This sequence is a reference standard in the RefSeqGene project. On Nov 23, 2018 this sequence version replaced NM_032830.2. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR3476690.1105789.1, AK027675.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000314423.12/ ENSP00000327179.7 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGGTGAAT TTAAGGTCCA TCGAGTACGT TTCTTTAATT ATGTTCCATC AGGAATCCGC 
TGTGTGGCTT ACAATAACCA GTCAAACAGA TTGGCTGTTT CACGAACAGA TGGCACTGTG 
GAAATTTATA ACTTGTCAGC AAACTACTTT CAGGAGAAAT TTTTCCCAGG TCATGAGTCT 
CGGGCTACAG AAGCTTTGTG CTGGGCAGAA GGACAGCGAC TCTTTAGTGC TGGGCTCAAT 
GGCGAGATTA TGGAGTATGA TTTACAGGCG TTAAACATCA AGTATGCTAT GGATGCCTTT 
GGAGGACCTA TTTGGAGCAT GGCTGCCAGC CCCAGTGGCT CTCAACTTTT GGTTGGTTGT 
GAAGATGGAT CTGTGAAACT ATTTCAAATT ACCCCAGACA AAATCCAGTT TGAAAGAAAT 
TTTGATCGGC AGAAAAGTCG CATCCTGAGT CTCAGCTGGC ATCCCTCTGG TACCCACATT 
GCAGCTGGTT CCATAGACTA CATTAGTGTG TTTGATGTCA AATCAGGCAG CGCTGTTCAT 
AAGATGATTG TGGACAGGCA GTATATGGGC GTGTCTAAGC GGAAGTGCAT CGTGTGGGGT 
GTCGCCTTCT TGTCCGATGG CACTATCATA AGTGTGGACT CTGCTGGGAA GGTGCAGTTC 
TGGGACTCAG CCACTGGGAC GCTTGTGAAG AGCCATCTCA TCGCTAATGC TGACGTGCAG 
TCCATTGCTG TAGCTGACCA AGAAGACAGT TTCGTGGTGG GCACAGCCGA GGGAACAGTC 
TTCCATTTTC AGCTGGTCCC TGTGACATCT AACAGCAGTG AGAAGCAGTG GGTGCGGACA 
AAACCGTTCC AGCATCACAC TCATGACGTG CGCACTGTGG CCCACAGCCC AACAGCGCTG 
ATATCTGGAG GCACTGACAC CCACTTAGTC TTTCGTCCTC TCATGGAGAA GGTGGAAGTA 
AAGAATTACG ATGCCGCTCT CCGAAAAATC ACCTTTCCCC ACCGATGTCT CATCTCCTGT 
TCTAAAAAGA GGCAGCTTCT CCTCTTCCAG TTTGCTCATC ACTTAGAACT TTGGCGACTG 
GGATCCACAG TTGCAACAGG CAAGAATGGG GATACTCTTC CACTCTCTAA AAATGCAGAT 
CATTTACTGC ACCTAAAGAC AAAGGGTCCT GAGAACATTA TCTGTAGCTG TATCTCCCCA 
TGTGGAAGTT GGATAGCCTA TTCTACAGTT TCTCGGTTTT TTCTCTATCG GCTGAATTAT 
GAACATGACA ACATAAGCCT CAAAAGGGTT TCCAAAATGC CAGCATTCCT TCGCTCTGCC 
CTTCAGATTT TGTTTTCTGA AGATTCAACA AAGCTCTTTG TAGCATCAAA TCAAGGAGCT 
CTGCATATTG TTCAGCTGTC AGGAGGAAGC TTCAAGCACC TGCATGCTTT CCAGCCTCAG 
TCAGGAACAG TGGAGGCCAT GTGTCTTTTG GCAGTCAGTC CAGATGGGAA TTGGCTAGCT 
GCATCAGGTA CCAGTGCTGG AGTCCATGTC TACAACGTAA AACAGCTAAA GCTTCACTGC 
ACGGTGCCTG CTTACAATTT CCCAGTGACT GCTATGGCTA TTGCCCCCAA TACCAACAAC 
CTTGTCATCG CTCATTCGGA CCAGCAGGTA TTTGAGTACA GCATCCCAGA CAAACAGTAT 
ACAGATTGGA GCCGGACTGT CCAGAAGCAG GGCTTTCACC ACCTTTGGCT CCAAAGGGAT 
ACTCCTATCA CACACATCAG TTTTCATCCC AAGAGACCGA TGCACATCCT TCTCCATGAT 
GCCTACATGT TCTGCATCAT TGACAAGTCA TTGCCCCTTC CAAATGACAA AACCTTACTC 
TACAATCCAT TTCCTCCCAC GAATGAATCA GATGTCATCC GGAGGCGCAC AGCTCATGCT 
TTTAAAATTT CTAAGATATA TAAGCCTCTA CTCTTCATGG ATCTTTTGGA TGAAAGAACA 
CTCGTGGCAG TAGAACGGCC TCTGGATGAC ATCATTGCTC AGCTCCCACC ACCCATTAAA 
AAGAAGAAAT TTGGAACCTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_116219.2
CDS	44..2104
Translation	MGEFKVHRVRFFNYVPSGIRCVAYNNQSNRLAVSRTDGTVEIYNLSANYFQEKFFPGHESRATEALCWAEGQRLFSAGLNGEIMEYDLQALNIKYAMDAFGGPIWSMAASPSGSQLLVGCEDGSVKLFQITPDKIQFERNFDRQKSRILSLSWHPSGTHIAAGSIDYISVFDVKSGSAVHKMIVDRQYMGVSKRKCIVWGVAFLSDGTIISVDSAGKVQFWDSATGTLVKSHLIANADVQSIAVADQEDSFVVGTAEGTVFHFQLVPVTSNSSEKQWVRTKPFQHHTHDVRTVAHSPTALISGGTDTHLVFRPLMEKVEVKNYDAALRKITFPHRCLISCSKKRQLLLFQFAHHLELWRLGSTVATGKNGDTLPLSKNADHLLHLKTKGPENIICSCISPCGSWIAYSTVSRFFLYRLNYEHDNISLKRVSKMPAFLRSALQILFSEDSTKLFVASNQGALHIVQLSGGSFKHLHAFQPQSGTVEAMCLLAVSPDGNWLAASGTSAGVHVYNVKQLKLHCTVPAYNFPVTAMAIAPNTNNLVIAHSDQQVFEYSIPDKQYTDWSRTVQKQGFHHLWLQRDTPITHISFHPKRPMHILLHDAYMFCIIDKSLPLPNDKTLLYNPFPPTNESDVIRRRTAHAFKISKIYKPLLFMDLLDERTLVAVERPLDDIIAQLPPPIKKKKFGT

Target ORF information:

RefSeq Version	NM_032830.3
Organism	Homo sapiens(human)
Definition	Homo sapiens UTP4 small subunit processome component (UTP4), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_032830.3

ORF Insert Sequence:

ATGGGTGAAT TTAAGGTCCA TCGAGTACGT TTCTTTAATT ATGTTCCATC AGGAATCCGC 
TGTGTGGCTT ACAATAACCA GTCAAACAGA TTGGCTGTTT CACGAACAGA TGGCACTGTG 
GAAATTTATA ACTTGTCAGC AAACTACTTT CAGGAGAAAT TTTTCCCAGG TCATGAGTCT 
CGGGCTACAG AAGCTTTGTG CTGGGCAGAA GGACAGCGAC TCTTTAGTGC TGGGCTCAAT 
GGCGAGATTA TGGAGTATGA TTTACAGGCG TTAAACATCA AGTATGCTAT GGATGCCTTT 
GGAGGACCTA TTTGGAGCAT GGCTGCCAGC CCCAGTGGCT CTCAACTTTT GGTTGGTTGT 
GAAGATGGAT CTGTGAAACT ATTTCAAATT ACCCCAGACA AAATCCAGTT TGAAAGAAAT 
TTTGATCGGC AGAAAAGTCG CATCCTGAGT CTCAGCTGGC ATCCCTCTGG TACCCACATT 
GCAGCTGGTT CCATAGACTA CATTAGTGTG TTTGATGTCA AATCAGGCAG CGCTGTTCAT 
AAGATGATTG TGGACAGGCA GTATATGGGC GTGTCTAAGC GGAAGTGCAT CGTGTGGGGT 
GTCGCCTTCT TGTCCGATGG CACTATCATA AGTGTGGACT CTGCTGGGAA GGTGCAGTTC 
TGGGACTCAG CCACTGGGAC GCTTGTGAAG AGCCATCTCA TCGCTAATGC TGACGTGCAG 
TCCATTGCTG TAGCTGACCA AGAAGACAGT TTCGTGGTGG GCACAGCCGA GGGAACAGTC 
TTCCATTTTC AGCTGGTCCC TGTGACATCT AACAGCAGTG AGAAGCAGTG GGTGCGGACA 
AAACCGTTCC AGCATCACAC TCATGACGTG CGCACTGTGG CCCACAGCCC AACAGCGCTG 
ATATCTGGAG GCACTGACAC CCACTTAGTC TTTCGTCCTC TCATGGAGAA GGTGGAAGTA 
AAGAATTACG ATGCCGCTCT CCGAAAAATC ACCTTTCCCC ACCGATGTCT CATCTCCTGT 
TCTAAAAAGA GGCAGCTTCT CCTCTTCCAG TTTGCTCATC ACTTAGAACT TTGGCGACTG 
GGATCCACAG TTGCAACAGG CAAGAATGGG GATACTCTTC CACTCTCTAA AAATGCAGAT 
CATTTACTGC ACCTAAAGAC AAAGGGTCCT GAGAACATTA TCTGTAGCTG TATCTCCCCA 
TGTGGAAGTT GGATAGCCTA TTCTACAGTT TCTCGGTTTT TTCTCTATCG GCTGAATTAT 
GAACATGACA ACATAAGCCT CAAAAGGGTT TCCAAAATGC CAGCATTCCT TCGCTCTGCC 
CTTCAGATTT TGTTTTCTGA AGATTCAACA AAGCTCTTTG TAGCATCAAA TCAAGGAGCT 
CTGCATATTG TTCAGCTGTC AGGAGGAAGC TTCAAGCACC TGCATGCTTT CCAGCCTCAG 
TCAGGAACAG TGGAGGCCAT GTGTCTTTTG GCAGTCAGTC CAGATGGGAA TTGGCTAGCT 
GCATCAGGTA CCAGTGCTGG AGTCCATGTC TACAACGTAA AACAGCTAAA GCTTCACTGC 
ACGGTGCCTG CTTACAATTT CCCAGTGACT GCTATGGCTA TTGCCCCCAA TACCAACAAC 
CTTGTCATCG CTCATTCGGA CCAGCAGGTA TTTGAGTACA GCATCCCAGA CAAACAGTAT 
ACAGATTGGA GCCGGACTGT CCAGAAGCAG GGCTTTCACC ACCTTTGGCT CCAAAGGGAT 
ACTCCTATCA CACACATCAG TTTTCATCCC AAGAGACCGA TGCACATCCT TCTCCATGAT 
GCCTACATGT TCTGCATCAT TGACAAGTCA TTGCCCCTTC CAAATGACAA AACCTTACTC 
TACAATCCAT TTCCTCCCAC GAATGAATCA GATGTCATCC GGAGGCGCAC AGCTCATGCT 
TTTAAAATTT CTAAGATATA TAAGCCTCTA CTCTTCATGG ATCTTTTGGA TGAAAGAACA 
CTCGTGGCAG TAGAACGGCC TCTGGATGAC ATCATTGCTC AGCTCCCACC ACCCATTAAA 
AAGAAGAAAT TTGGAACCTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

UTP4 ( NM_001318391.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001305320.1 Homo sapiens UTP4 small subunit processome component (UTP4), transcript variant 2, mRNA.

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CloneID	OHu49549
Clone ID Related Accession (Same CDS sequence)	NM_001318391.1
Accession Version	NM_001318391.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1812bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-10
Organism	Homo sapiens(human)
Product	U3 small nucleolar RNA-associated protein 4 homolog isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DC368305.1, BX647265.1 and CA430627.1. On Jan 6, 2016 this sequence version replaced XM_005256204.1. Transcript Variant: This variant (2) differs in the 5' UTR, lacks a portion of the 5' coding region and initiates translation at a downstream start codon, compared to variant 1. It encodes isoform 2, which has a shorter N-terminus, compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BX647265.1, SRR1803611.84400.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGAGTATG ATTTACAGGC GTTAAACATC AAGTATGCTA TGGATGCCTT TGGAGGACCT 
ATTTGGAGCA TGGCTGCCAG CCCCAGTGGC TCTCAACTTT TGGTTGGTTG TGAAGATGGA 
TCTGTGAAAC TATTTCAAAT TACCCCAGAC AAAATCCAGT TTGAAAGAAA TTTTGATCGG 
CAGAAAAGTC GCATCCTGAG TCTCAGCTGG CATCCCTCTG GTACCCACAT TGCAGCTGGT 
TCCATAGACT ACATTAGTGT GTTTGATGTC AAATCAGGCA GCGCTGTTCA TAAGATGATT 
GTGGACAGGC AGTATATGGG CGTGTCTAAG CGGAAGTGCA TCGTGTGGGG TGTCGCCTTC 
TTGTCCGATG GCACTATCAT AAGTGTGGAC TCTGCTGGGA AGGTGCAGTT CTGGGACTCA 
GCCACTGGGA CGCTTGTGAA GAGCCATCTC ATCGCTAATG CTGACGTGCA GTCCATTGCT 
GTAGCTGACC AAGAAGACAG TTTCGTGGTG GGCACAGCCG AGGGAACAGT CTTCCATTTT 
CAGCTGGTCC CTGTGACATC TAACAGCAGT GAGAAGCAGT GGGTGCGGAC AAAACCGTTC 
CAGCATCACA CTCATGACGT GCGCACTGTG GCCCACAGCC CAACAGCGCT GATATCTGGA 
GGCACTGACA CCCACTTAGT CTTTCGTCCT CTCATGGAGA AGGTGGAAGT AAAGAATTAC 
GATGCCGCTC TCCGAAAAAT CACCTTTCCC CACCGATGTC TCATCTCCTG TTCTAAAAAG 
AGGCAGCTTC TCCTCTTCCA GTTTGCTCAT CACTTAGAAC TTTGGCGACT GGGATCCACA 
GTTGCAACAG GCAAGAATGG GGATACTCTT CCACTCTCTA AAAATGCAGA TCATTTACTG 
CACCTAAAGA CAAAGGGTCC TGAGAACATT ATCTGTAGCT GTATCTCCCC ATGTGGAAGT 
TGGATAGCCT ATTCTACAGT TTCTCGGTTT TTTCTCTATC GGCTGAATTA TGAACATGAC 
AACATAAGCC TCAAAAGGGT TTCCAAAATG CCAGCATTCC TTCGCTCTGC CCTTCAGATT 
TTGTTTTCTG AAGATTCAAC AAAGCTCTTT GTAGCATCAA ATCAAGGAGC TCTGCATATT 
GTTCAGCTGT CAGGAGGAAG CTTCAAGCAC CTGCATGCTT TCCAGCCTCA GTCAGGAACA 
GTGGAGGCCA TGTGTCTTTT GGCAGTCAGT CCAGATGGGA ATTGGCTAGC TGCATCAGGT 
ACCAGTGCTG GAGTCCATGT CTACAACGTA AAACAGCTAA AGCTTCACTG CACGGTGCCT 
GCTTACAATT TCCCAGTGAC TGCTATGGCT ATTGCCCCCA ATACCAACAA CCTTGTCATC 
GCTCATTCGG ACCAGCAGGT ATTTGAGTAC AGCATCCCAG ACAAACAGTA TACAGATTGG 
AGCCGGACTG TCCAGAAGCA GGGCTTTCAC CACCTTTGGC TCCAAAGGGA TACTCCTATC 
ACACACATCA GTTTTCATCC CAAGAGACCG ATGCACATCC TTCTCCATGA TGCCTACATG 
TTCTGCATCA TTGACAAGTC ATTGCCCCTT CCAAATGACA AAACCTTACT CTACAATCCA 
TTTCCTCCCA CGAATGAATC AGATGTCATC CGGAGGCGCA CAGCTCATGC TTTTAAAATT 
TCTAAGATAT ATAAGCCTCT ACTCTTCATG GATCTTTTGG ATGAAAGAAC ACTCGTGGCA 
GTAGAACGGC CTCTGGATGA CATCATTGCT CAGCTCCCAC CACCCATTAA AAAGAAGAAA 
TTTGGAACCT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001305320.1
CDS	292..2103
Translation	MEYDLQALNIKYAMDAFGGPIWSMAASPSGSQLLVGCEDGSVKLFQITPDKIQFERNFDRQKSRILSLSWHPSGTHIAAGSIDYISVFDVKSGSAVHKMIVDRQYMGVSKRKCIVWGVAFLSDGTIISVDSAGKVQFWDSATGTLVKSHLIANADVQSIAVADQEDSFVVGTAEGTVFHFQLVPVTSNSSEKQWVRTKPFQHHTHDVRTVAHSPTALISGGTDTHLVFRPLMEKVEVKNYDAALRKITFPHRCLISCSKKRQLLLFQFAHHLELWRLGSTVATGKNGDTLPLSKNADHLLHLKTKGPENIICSCISPCGSWIAYSTVSRFFLYRLNYEHDNISLKRVSKMPAFLRSALQILFSEDSTKLFVASNQGALHIVQLSGGSFKHLHAFQPQSGTVEAMCLLAVSPDGNWLAASGTSAGVHVYNVKQLKLHCTVPAYNFPVTAMAIAPNTNNLVIAHSDQQVFEYSIPDKQYTDWSRTVQKQGFHHLWLQRDTPITHISFHPKRPMHILLHDAYMFCIIDKSLPLPNDKTLLYNPFPPTNESDVIRRRTAHAFKISKIYKPLLFMDLLDERTLVAVERPLDDIIAQLPPPIKKKKFGT

Target ORF information:

RefSeq Version	NM_001318391.1
Organism	Homo sapiens(human)
Definition	Homo sapiens UTP4 small subunit processome component (UTP4), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001318391.1

ORF Insert Sequence:

ATGGAGTATG ATTTACAGGC GTTAAACATC AAGTATGCTA TGGATGCCTT TGGAGGACCT 
ATTTGGAGCA TGGCTGCCAG CCCCAGTGGC TCTCAACTTT TGGTTGGTTG TGAAGATGGA 
TCTGTGAAAC TATTTCAAAT TACCCCAGAC AAAATCCAGT TTGAAAGAAA TTTTGATCGG 
CAGAAAAGTC GCATCCTGAG TCTCAGCTGG CATCCCTCTG GTACCCACAT TGCAGCTGGT 
TCCATAGACT ACATTAGTGT GTTTGATGTC AAATCAGGCA GCGCTGTTCA TAAGATGATT 
GTGGACAGGC AGTATATGGG CGTGTCTAAG CGGAAGTGCA TCGTGTGGGG TGTCGCCTTC 
TTGTCCGATG GCACTATCAT AAGTGTGGAC TCTGCTGGGA AGGTGCAGTT CTGGGACTCA 
GCCACTGGGA CGCTTGTGAA GAGCCATCTC ATCGCTAATG CTGACGTGCA GTCCATTGCT 
GTAGCTGACC AAGAAGACAG TTTCGTGGTG GGCACAGCCG AGGGAACAGT CTTCCATTTT 
CAGCTGGTCC CTGTGACATC TAACAGCAGT GAGAAGCAGT GGGTGCGGAC AAAACCGTTC 
CAGCATCACA CTCATGACGT GCGCACTGTG GCCCACAGCC CAACAGCGCT GATATCTGGA 
GGCACTGACA CCCACTTAGT CTTTCGTCCT CTCATGGAGA AGGTGGAAGT AAAGAATTAC 
GATGCCGCTC TCCGAAAAAT CACCTTTCCC CACCGATGTC TCATCTCCTG TTCTAAAAAG 
AGGCAGCTTC TCCTCTTCCA GTTTGCTCAT CACTTAGAAC TTTGGCGACT GGGATCCACA 
GTTGCAACAG GCAAGAATGG GGATACTCTT CCACTCTCTA AAAATGCAGA TCATTTACTG 
CACCTAAAGA CAAAGGGTCC TGAGAACATT ATCTGTAGCT GTATCTCCCC ATGTGGAAGT 
TGGATAGCCT ATTCTACAGT TTCTCGGTTT TTTCTCTATC GGCTGAATTA TGAACATGAC 
AACATAAGCC TCAAAAGGGT TTCCAAAATG CCAGCATTCC TTCGCTCTGC CCTTCAGATT 
TTGTTTTCTG AAGATTCAAC AAAGCTCTTT GTAGCATCAA ATCAAGGAGC TCTGCATATT 
GTTCAGCTGT CAGGAGGAAG CTTCAAGCAC CTGCATGCTT TCCAGCCTCA GTCAGGAACA 
GTGGAGGCCA TGTGTCTTTT GGCAGTCAGT CCAGATGGGA ATTGGCTAGC TGCATCAGGT 
ACCAGTGCTG GAGTCCATGT CTACAACGTA AAACAGCTAA AGCTTCACTG CACGGTGCCT 
GCTTACAATT TCCCAGTGAC TGCTATGGCT ATTGCCCCCA ATACCAACAA CCTTGTCATC 
GCTCATTCGG ACCAGCAGGT ATTTGAGTAC AGCATCCCAG ACAAACAGTA TACAGATTGG 
AGCCGGACTG TCCAGAAGCA GGGCTTTCAC CACCTTTGGC TCCAAAGGGA TACTCCTATC 
ACACACATCA GTTTTCATCC CAAGAGACCG ATGCACATCC TTCTCCATGA TGCCTACATG 
TTCTGCATCA TTGACAAGTC ATTGCCCCTT CCAAATGACA AAACCTTACT CTACAATCCA 
TTTCCTCCCA CGAATGAATC AGATGTCATC CGGAGGCGCA CAGCTCATGC TTTTAAAATT 
TCTAAGATAT ATAAGCCTCT ACTCTTCATG GATCTTTTGG ATGAAAGAAC ACTCGTGGCA 
GTAGAACGGC CTCTGGATGA CATCATTGCT CAGCTCCCAC CACCCATTAA AAAGAAGAAA 
TTTGGAACCT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

UTP4 ( XM_005256205.3 ) cDNA ORF clone, Homo sapiens(human) -> XP_005256262.2 Homo sapiens UTP4 small subunit processome component (UTP4), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu73851
Clone ID Related Accession (Same CDS sequence)	XM_005256205.3
Accession Version	XM_005256205.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1644bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	U3 small nucleolar RNA-associated protein 4 homolog isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000016.10) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_005256205.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGATCTGGC TGGACTGCTT ATTTGGGGTA GCCCTGAAGC CAGAATCTTC AGATCTTTTC 
TTTTGTGTCA GTTATGTTCC TCAGAAATGG TTTTTCATTC TCCTGCCTGG CAGCGCTGTT 
CATAAGATGA TTGTGGACAG GCAGTATATG GGCGTGTCTA AGCGGAAGTG CATCGTGTGG 
GGTGTCGCCT TCTTGTCCGA TGGCACTATC ATAAGTGTGG ACTCTGCTGG GAAGGTGCAG 
TTCTGGGACT CAGCCACTGG GACGCTTGTG AAGAGCCATC TCATCGCTAA TGCTGACGTG 
CAGTCCATTG CTGTAGCTGA CCAAGAAGAC AGTTTCGTGG TGGGCACAGC CGAGGGAACA 
GTCTTCCATT TTCAGCTGGT CCCTGTGACA TCTAACAGCA GTGAGAAGCA GTGGGTGCGG 
ACAAAACCGT TCCAGCATCA CACTCATGAC GTGCGCACTG TGGCCCACAG CCCAACAGCG 
CTGATATCTG GAGGCACTGA CACCCACTTA GTCTTTCGTC CTCTCATGGA GAAGGTGGAA 
GTAAAGAATT ACGATGCCGC TCTCCGAAAA ATCACCTTTC CCCACCGATG TCTCATCTCC 
TGTTCTAAAA AGAGGCAGCT TCTCCTCTTC CAGTTTGCTC ATCACTTAGA ACTTTGGCGA 
CTGGGATCCA CAGTTGCAAC AGGCAAGAAT GGGGATACTC TTCCACTCTC TAAAAATGCA 
GATCATTTAC TGCACCTAAA GACAAAGGGT CCTGAGAACA TTATCTGTAG CTGTATCTCC 
CCATGTGGAA GTTGGATAGC CTATTCTACA GTTTCTCGGT TTTTTCTCTA TCGGCTGAAT 
TATGAACATG ACAACATAAG CCTCAAAAGG GTTTCCAAAA TGCCAGCATT CCTTCGCTCT 
GCCCTTCAGA TTTTGTTTTC TGAAGATTCA ACAAAGCTCT TTGTAGCATC AAATCAAGGA 
GCTCTGCATA TTGTTCAGCT GTCAGGAGGA AGCTTCAAGC ACCTGCATGC TTTCCAGCCT 
CAGTCAGGAA CAGTGGAGGC CATGTGTCTT TTGGCAGTCA GTCCAGATGG GAATTGGCTA 
GCTGCATCAG GTACCAGTGC TGGAGTCCAT GTCTACAACG TAAAACAGCT AAAGCTTCAC 
TGCACGGTGC CTGCTTACAA TTTCCCAGTG ACTGCTATGG CTATTGCCCC CAATACCAAC 
AACCTTGTCA TCGCTCATTC GGACCAGCAG GTATTTGAGT ACAGCATCCC AGACAAACAG 
TATACAGATT GGAGCCGGAC TGTCCAGAAG CAGGGCTTTC ACCACCTTTG GCTCCAAAGG 
GATACTCCTA TCACACACAT CAGTTTTCAT CCCAAGAGAC CGATGCACAT CCTTCTCCAT 
GATGCCTACA TGTTCTGCAT CATTGACAAG TCATTGCCCC TTCCAAATGA CAAAACCTTA 
CTCTACAATC CATTTCCTCC CACGAATGAA TCAGATGTCA TCCGGAGGCG CACAGCTCAT 
GCTTTTAAAA TTTCTAAGAT ATATAAGCCT CTACTCTTCA TGGATCTTTT GGATGAAAGA 
ACACTCGTGG CAGTAGAACG GCCTCTGGAT GACATCATTG CTCAGCTCCC ACCACCCATT 
AAAAAGAAGA AATTTGGAAC CTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005256262.2
CDS	45..1688
Translation	MIWLDCLFGVALKPESSDLFFCVSYVPQKWFFILLPGSAVHKMIVDRQYMGVSKRKCIVWGVAFLSDGTIISVDSAGKVQFWDSATGTLVKSHLIANADVQSIAVADQEDSFVVGTAEGTVFHFQLVPVTSNSSEKQWVRTKPFQHHTHDVRTVAHSPTALISGGTDTHLVFRPLMEKVEVKNYDAALRKITFPHRCLISCSKKRQLLLFQFAHHLELWRLGSTVATGKNGDTLPLSKNADHLLHLKTKGPENIICSCISPCGSWIAYSTVSRFFLYRLNYEHDNISLKRVSKMPAFLRSALQILFSEDSTKLFVASNQGALHIVQLSGGSFKHLHAFQPQSGTVEAMCLLAVSPDGNWLAASGTSAGVHVYNVKQLKLHCTVPAYNFPVTAMAIAPNTNNLVIAHSDQQVFEYSIPDKQYTDWSRTVQKQGFHHLWLQRDTPITHISFHPKRPMHILLHDAYMFCIIDKSLPLPNDKTLLYNPFPPTNESDVIRRRTAHAFKISKIYKPLLFMDLLDERTLVAVERPLDDIIAQLPPPIKKKKFGT

Target ORF information:

RefSeq Version	XM_005256205.3
Organism	Homo sapiens(human)
Definition	Homo sapiens UTP4 small subunit processome component (UTP4), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005256205.3

ORF Insert Sequence:

ATGATCTGGC TGGACTGCTT ATTTGGGGTA GCCCTGAAGC CAGAATCTTC AGATCTTTTC 
TTTTGTGTCA GTTATGTTCC TCAGAAATGG TTTTTCATTC TCCTGCCTGG CAGCGCTGTT 
CATAAGATGA TTGTGGACAG GCAGTATATG GGCGTGTCTA AGCGGAAGTG CATCGTGTGG 
GGTGTCGCCT TCTTGTCCGA TGGCACTATC ATAAGTGTGG ACTCTGCTGG GAAGGTGCAG 
TTCTGGGACT CAGCCACTGG GACGCTTGTG AAGAGCCATC TCATCGCTAA TGCTGACGTG 
CAGTCCATTG CTGTAGCTGA CCAAGAAGAC AGTTTCGTGG TGGGCACAGC CGAGGGAACA 
GTCTTCCATT TTCAGCTGGT CCCTGTGACA TCTAACAGCA GTGAGAAGCA GTGGGTGCGG 
ACAAAACCGT TCCAGCATCA CACTCATGAC GTGCGCACTG TGGCCCACAG CCCAACAGCG 
CTGATATCTG GAGGCACTGA CACCCACTTA GTCTTTCGTC CTCTCATGGA GAAGGTGGAA 
GTAAAGAATT ACGATGCCGC TCTCCGAAAA ATCACCTTTC CCCACCGATG TCTCATCTCC 
TGTTCTAAAA AGAGGCAGCT TCTCCTCTTC CAGTTTGCTC ATCACTTAGA ACTTTGGCGA 
CTGGGATCCA CAGTTGCAAC AGGCAAGAAT GGGGATACTC TTCCACTCTC TAAAAATGCA 
GATCATTTAC TGCACCTAAA GACAAAGGGT CCTGAGAACA TTATCTGTAG CTGTATCTCC 
CCATGTGGAA GTTGGATAGC CTATTCTACA GTTTCTCGGT TTTTTCTCTA TCGGCTGAAT 
TATGAACATG ACAACATAAG CCTCAAAAGG GTTTCCAAAA TGCCAGCATT CCTTCGCTCT 
GCCCTTCAGA TTTTGTTTTC TGAAGATTCA ACAAAGCTCT TTGTAGCATC AAATCAAGGA 
GCTCTGCATA TTGTTCAGCT GTCAGGAGGA AGCTTCAAGC ACCTGCATGC TTTCCAGCCT 
CAGTCAGGAA CAGTGGAGGC CATGTGTCTT TTGGCAGTCA GTCCAGATGG GAATTGGCTA 
GCTGCATCAG GTACCAGTGC TGGAGTCCAT GTCTACAACG TAAAACAGCT AAAGCTTCAC 
TGCACGGTGC CTGCTTACAA TTTCCCAGTG ACTGCTATGG CTATTGCCCC CAATACCAAC 
AACCTTGTCA TCGCTCATTC GGACCAGCAG GTATTTGAGT ACAGCATCCC AGACAAACAG 
TATACAGATT GGAGCCGGAC TGTCCAGAAG CAGGGCTTTC ACCACCTTTG GCTCCAAAGG 
GATACTCCTA TCACACACAT CAGTTTTCAT CCCAAGAGAC CGATGCACAT CCTTCTCCAT 
GATGCCTACA TGTTCTGCAT CATTGACAAG TCATTGCCCC TTCCAAATGA CAAAACCTTA 
CTCTACAATC CATTTCCTCC CACGAATGAA TCAGATGTCA TCCGGAGGCG CACAGCTCAT 
GCTTTTAAAA TTTCTAAGAT ATATAAGCCT CTACTCTTCA TGGATCTTTT GGATGAAAGA 
ACACTCGTGG CAGTAGAACG GCCTCTGGAT GACATCATTG CTCAGCTCCC ACCACCCATT 
AAAAAGAAGA AATTTGGAAC CTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Architecture of the human interactome defines protein communities and disease networks.
Nature545(7655)505-509(2017 05)
Huttlin EL,Bruckner RJ,Paulo JA,Cannon JR,Ting L,Baltier K,Colby G,Gebreab F,Gygi MP,Parzen H,Szpyt J,Tam S,Zarraga G,Pontano-Vaites L,Swarup S,White AE,Schweppe DK,Rad R,Erickson BK,Obar RA,Guruharsha KG,Li K,Artavanis-Tsakonas S,Gygi SP,Harper JW

CIRH1A augments the proliferation of RKO colorectal cancer cells.
Oncology reports37(4)2375-2381(2017 Apr)
Guo F,Chen JJ,Tang WJ

Interaction, mobility, and phosphorylation of human orthologues of WD repeat-containing components of the yeast SSU processome t-UTP sub-complex.
Biochemistry and cell biology = Biochimie et biologie cellulaire91(6)466-75(2013 Dec)
Sato M,Araki N,Kumeta M,Takeyasu K,Taguchi Y,Asai T,Furukawa K,Horigome T

Insights into RNA biology from an atlas of mammalian mRNA-binding proteins.
Cell149(6)1393-406(2012 Jun)
Castello A,Fischer B,Eichelbaum K,Horos R,Beckmann BM,Strein C,Davey NE,Humphreys DT,Preiss T,Steinmetz LM,Krijgsveld J,Hentze MW

NOL11, implicated in the pathogenesis of North American Indian childhood cirrhosis, is required for pre-rRNA transcription and processing.
PLoS genetics8(8)e1002892(2012)
Freed EF,Prieto JL,McCann KL,McStay B,Baserga SJ

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UTP4 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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