TMEM87B cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	TMEM87B
Entrez Gene ID	84910
Full Name	transmembrane protein 87B
General protein information	Preferred Names transmembrane protein 87B Names transmembrane protein 87B
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 2 Map Location: 2q13
Summary	This gene encodes a protein that may interact with human papillomavirus type 18 E6 oncogene. The protein is also likely to be involved in endosome-to-trans-Golgi network retrograde transport. The gene is expressed in adult and fetal tissues, including brain and heart. This gene is a component of the 2q13 deletion syndrome. Mutations in this gene may be associated with congenital heart defects. [provided by RefSeq, Aug 2016].
Disorder MIM:	617203

mRNA and Protein(s)

mRNA	Protein	Name
NM_032824.2	NP_116213.1	transmembrane protein 87B isoform 1 precursor
NM_001329914.1	NP_001316843.1	transmembrane protein 87B isoform 2 precursor
NM_032824.3	NP_116213.1	transmembrane protein 87B isoform 1 precursor
XM_005263827.2	XP_005263884.1	transmembrane protein 87B isoform X1
XM_017005121.1	XP_016860610.1	transmembrane protein 87B isoform X2
NM_001329914.2	NP_001316843.1	transmembrane protein 87B isoform 2 precursor

Pathways from BioSystems

Homologies

Homo sapiens (human)	TMEM87B	NP_116213.1
	TMEM87B	XP_001087195.1
Danio rerio (zebrafish)	tmem87b	XP_002664278.3
Canis lupus familiaris (dog)	TMEM87B	XP_005630496.1
Bos taurus (cattle)	TMEM87B	XP_002691201.2
Rattus norvegicus (Norway rat)	Tmem87b	NP_001178783.1
Mus musculus (house mouse)	Tmem87b	NP_082524.2
Drosophila melanogaster (fruit fly)	CG17660	NP_608612.3
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP007934	XP_317548.3
Xenopus tropicalis (tropical clawed frog)	tmem87b	NP_001016057.1
Pan troglodytes (chimpanzee)	TMEM87B	XP_001141265.3
Caenorhabditis elegans (roundworm)	C52B9.4	NP_508729.2

Gene Ontology
Bibliography

Related articles in PubMed

Discovery of a potentially deleterious variant in TMEM87B in a patient with a hemizygous 2q13 microdeletion suggests a recessive condition characterized by congenital heart disease and restrictive cardiomyopathy.
Yu HC, Coughlin CR, Geiger EA, Salvador BJ, Elias ER, Cavanaugh JL, Chatfield KC, Miyamoto SD, Shaikh TH
Cold Spring Harbor molecular case studies2(3)a000844(2016 May)

Recurrent deletions and duplications of chromosome 2q11.2 and 2q13 are associated with variable outcomes.
Riley KN, Catalano LM, Bernat JA, Adams SD, Martin DM, Lalani SR, Patel A, Burnside RD, Innis JW, Rudd MK
American journal of medical genetics. Part A167A(11)2664-73(2015 Nov)

Post-Golgi anterograde transport requires GARP-dependent endosome-to-TGN retrograde transport.
Hirata T, Fujita M, Nakamura S, Gotoh K, Motooka D, Murakami Y, Maeda Y, Kinoshita T
Molecular biology of the cell26(17)3071-84(2015 Sep)

A recurrent deletion on chromosome 2q13 is associated with developmental delay and mild facial dysmorphisms.
Hladilkova E, Bar?y T, Fannemel M, Vallova V, Misceo D, Bryn V, Slamova I, Prasilova S, Kuglik P, Frengen E
Molecular cytogenetics857(2015)

Functional analysis of candidate genes in 2q13 deletion syndrome implicates FBLN7 and TMEM87B deficiency in congenital heart defects and FBLN7 in craniofacial malformations.
Russell MW, Raeker MO, Geisler SB, Thomas PE, Simmons TA, Bernat JA, Thorsson T, Innis JW
Human molecular genetics23(16)4272-84(2014 Aug)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Heterozygous loss of FBLN7 and TMEM87B account for some of the clinical features, including cardiac defects and craniofacial abnormalities associated with 2q13 deletion syndrome.
Title: Functional analysis of candidate genes in 2q13 deletion syndrome implicates FBLN7 and TMEM87B deficiency in congenital heart defects and FBLN7 in craniofacial malformations.

The following TMEM87B gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the TMEM87B cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu36700	XM_005263827.2 Latest version!	Homo sapiens transmembrane protein 87B (TMEM87B), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$307.30 $439.00
OHu10962	NM_032824.3 Latest version!	Homo sapiens transmembrane protein 87B (TMEM87B), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
OHu36699	NM_001329914.2 Latest version!	Homo sapiens transmembrane protein 87B (TMEM87B), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
OHu90001	XM_017005121.1 Latest version!	Homo sapiens transmembrane protein 87B (TMEM87B), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
View Old Accession Versions >>
OHu10962	NM_032824.2	Homo sapiens transmembrane protein 87B (TMEM87B), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
OHu36699	NM_001329914.1	Homo sapiens transmembrane protein 87B (TMEM87B), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

TMEM87B ( XM_005263827.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_005263884.1 Homo sapiens transmembrane protein 87B (TMEM87B), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu36700
Clone ID Related Accession (Same CDS sequence)	XM_005263827.2
Accession Version	XM_005263827.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1665bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	transmembrane protein 87B isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000002.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_005263827.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGTCGCCG CCTGCCGCTC GGTAGCCGGG CTCCTGCCAC GCCGCCGCCG CTGCTTTCCC 
GCCCGGGCCC CGCTGCTGCG CGTCGCCCTC TGCCTCCTGT GCTGGACCCC GGCGGCTGTG 
CGCGCGGTCC CTGAGCTCGG GCTCTGGTTA GAGACAGTCA ACGACAAATC AGGACCTTTG 
ATATTTAGGA AAACTATGTT TAACTCTACA GATATCAAGT TATCTGTTAA GTCATTCCAT 
TGTTCTGGGC CTGTGAAGTT TACCATAGTG TGGCATTTGA AGTATCATAC CTGTCACAAT 
GAGCATTCTA ATCTGGAAGA GCTGTTCCAA AAACATAAAC TTAGTGTTGA TGAAGACTTT 
TGTCATTATT TGAAGAATGA CAACTGTTGG ACAACAAAAA ATGAAAACTT AGATTGCAAC 
AGTGATTCAC AGGTGTTTCC CTCTTTGAAT AATAAAGAAC TAATAAATAT CAGAAATGTT 
TCAAACCAGG AAAGATCGGA TGTTGTAGCC AGAACACAAA AAGATGGGTT TCATATCTTT 
ATTGTTTCTA TTAAAACGGA GAATACAGAT GCAAGCTGGA ATTTGAATGT TTCTCTTTCT 
ATGATTGGGC CTCATGGATA TATCTCTGCA TCAGATTGGC CCCTAATGAT TTTTTACATG 
GTGATGTGTA TTGTTTATAT ATTATATGGC ATACTCTGGC TGACGTGGTC TGCCTGTTAT 
TGGAAAGATA TATTAAGAAT CCAGTTCTGG ATTGCAGCTG TTATTTTTTT GGGAATGCTT 
GAAAAAGCAG TTTTTTATAG TGAATACCAA AACATCAGCA ACACTGGACT GTCAACCCAA 
GGCTTATTGA TATTTGCGGA GTTGATTTCT GCGATTAAGA GGACGTTGGC TCGCCTTCTC 
GTGATCATTG TGAGCCTGGG CTATGGCATT GTGAAGCCTC GTTTAGGAAC AGTCATGCAC 
CGGGTGATCG GACTGGGGCT TCTATACTTA ATCTTTGCAG CTGTTGAAGG CGTGATGAGA 
GTCATTGGGG GTTCTAACCA TTTAGCTGTT GTTCTTGATG ACATTATTTT AGCAGTTATT 
GACTCCATTT TTGTGTGGTT CATTTTTATT AGTTTGGCAC AAACTATGAA GACCCTAAGG 
CTAAGAAAGA ACACTGTGAA ATTTTCATTA TATAGACATT TTAAAAATAC TCTGATCTTT 
GCTGTGCTGG CTTCTATAGT GTTTATGGGG TGGACAACTA AGACATTTAG AATTGCAAAA 
TGCCAATCAG ATTGGATGGA ACGCTGGGTT GACGATGCAT TTTGGAGCTT CCTTTTTTCG 
CTTATCCTTA TTGTAATCAT GTTTTTGTGG AGACCATCAG CAAACAATCA GAGATATGCC 
TTCATGCCCT TAATAGATGA TTCTGATGAT GAAATTGAGG AATTCATGGT AACTTCTGAA 
AATTTAACCG AAGGAATAAA ATTAAGAGCC TCAAAATCAG TTTCCAATGG AACAGCTAAG 
CCTGCCACTT CTGAGAACTT TGATGAAGAT TTGAAGTGGG TAGAAGAAAA TATTCCCTCT 
TCATTCACAG ATGTAGCTCT TCCAGTGTTA GTGGATTCAG ATGAGGAAAT CATGACCAGA 
TCTGAAATGG CTGAAAAAAT GTTCTCTTCA GAAAAGATAA TGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005263884.1
CDS	327..1991
Translation	MVAACRSVAGLLPRRRRCFPARAPLLRVALCLLCWTPAAVRAVPELGLWLETVNDKSGPLIFRKTMFNSTDIKLSVKSFHCSGPVKFTIVWHLKYHTCHNEHSNLEELFQKHKLSVDEDFCHYLKNDNCWTTKNENLDCNSDSQVFPSLNNKELINIRNVSNQERSDVVARTQKDGFHIFIVSIKTENTDASWNLNVSLSMIGPHGYISASDWPLMIFYMVMCIVYILYGILWLTWSACYWKDILRIQFWIAAVIFLGMLEKAVFYSEYQNISNTGLSTQGLLIFAELISAIKRTLARLLVIIVSLGYGIVKPRLGTVMHRVIGLGLLYLIFAAVEGVMRVIGGSNHLAVVLDDIILAVIDSIFVWFIFISLAQTMKTLRLRKNTVKFSLYRHFKNTLIFAVLASIVFMGWTTKTFRIAKCQSDWMERWVDDAFWSFLFSLILIVIMFLWRPSANNQRYAFMPLIDDSDDEIEEFMVTSENLTEGIKLRASKSVSNGTAKPATSENFDEDLKWVEENIPSSFTDVALPVLVDSDEEIMTRSEMAEKMFSSEKIM

Target ORF information:

RefSeq Version	XM_005263827.2
Organism	Homo sapiens(human)
Definition	Homo sapiens transmembrane protein 87B (TMEM87B), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005263827.2

ORF Insert Sequence:

ATGGTCGCCG CCTGCCGCTC GGTAGCCGGG CTCCTGCCAC GCCGCCGCCG CTGCTTTCCC 
GCCCGGGCCC CGCTGCTGCG CGTCGCCCTC TGCCTCCTGT GCTGGACCCC GGCGGCTGTG 
CGCGCGGTCC CTGAGCTCGG GCTCTGGTTA GAGACAGTCA ACGACAAATC AGGACCTTTG 
ATATTTAGGA AAACTATGTT TAACTCTACA GATATCAAGT TATCTGTTAA GTCATTCCAT 
TGTTCTGGGC CTGTGAAGTT TACCATAGTG TGGCATTTGA AGTATCATAC CTGTCACAAT 
GAGCATTCTA ATCTGGAAGA GCTGTTCCAA AAACATAAAC TTAGTGTTGA TGAAGACTTT 
TGTCATTATT TGAAGAATGA CAACTGTTGG ACAACAAAAA ATGAAAACTT AGATTGCAAC 
AGTGATTCAC AGGTGTTTCC CTCTTTGAAT AATAAAGAAC TAATAAATAT CAGAAATGTT 
TCAAACCAGG AAAGATCGGA TGTTGTAGCC AGAACACAAA AAGATGGGTT TCATATCTTT 
ATTGTTTCTA TTAAAACGGA GAATACAGAT GCAAGCTGGA ATTTGAATGT TTCTCTTTCT 
ATGATTGGGC CTCATGGATA TATCTCTGCA TCAGATTGGC CCCTAATGAT TTTTTACATG 
GTGATGTGTA TTGTTTATAT ATTATATGGC ATACTCTGGC TGACGTGGTC TGCCTGTTAT 
TGGAAAGATA TATTAAGAAT CCAGTTCTGG ATTGCAGCTG TTATTTTTTT GGGAATGCTT 
GAAAAAGCAG TTTTTTATAG TGAATACCAA AACATCAGCA ACACTGGACT GTCAACCCAA 
GGCTTATTGA TATTTGCGGA GTTGATTTCT GCGATTAAGA GGACGTTGGC TCGCCTTCTC 
GTGATCATTG TGAGCCTGGG CTATGGCATT GTGAAGCCTC GTTTAGGAAC AGTCATGCAC 
CGGGTGATCG GACTGGGGCT TCTATACTTA ATCTTTGCAG CTGTTGAAGG CGTGATGAGA 
GTCATTGGGG GTTCTAACCA TTTAGCTGTT GTTCTTGATG ACATTATTTT AGCAGTTATT 
GACTCCATTT TTGTGTGGTT CATTTTTATT AGTTTGGCAC AAACTATGAA GACCCTAAGG 
CTAAGAAAGA ACACTGTGAA ATTTTCATTA TATAGACATT TTAAAAATAC TCTGATCTTT 
GCTGTGCTGG CTTCTATAGT GTTTATGGGG TGGACAACTA AGACATTTAG AATTGCAAAA 
TGCCAATCAG ATTGGATGGA ACGCTGGGTT GACGATGCAT TTTGGAGCTT CCTTTTTTCG 
CTTATCCTTA TTGTAATCAT GTTTTTGTGG AGACCATCAG CAAACAATCA GAGATATGCC 
TTCATGCCCT TAATAGATGA TTCTGATGAT GAAATTGAGG AATTCATGGT AACTTCTGAA 
AATTTAACCG AAGGAATAAA ATTAAGAGCC TCAAAATCAG TTTCCAATGG AACAGCTAAG 
CCTGCCACTT CTGAGAACTT TGATGAAGAT TTGAAGTGGG TAGAAGAAAA TATTCCCTCT 
TCATTCACAG ATGTAGCTCT TCCAGTGTTA GTGGATTCAG ATGAGGAAAT CATGACCAGA 
TCTGAAATGG CTGAAAAAAT GTTCTCTTCA GAAAAGATAA TGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TMEM87B ( NM_032824.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_116213.1 Homo sapiens transmembrane protein 87B (TMEM87B), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu10962
Clone ID Related Accession (Same CDS sequence)	NM_032824.2 , NM_032824.3
Accession Version	NM_032824.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1668bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-01
Organism	Homo sapiens(human)
Product	transmembrane protein 87B isoform 1 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA806277.1, AC093675.4, DA550235.1, AK027587.1, AK074243.1, AC092645.2 and AI806006.1. This sequence is a reference standard in the RefSeqGene project. On Nov 26, 2008 this sequence version replaced NM_032824.1. Transcript Variant: This variant (1) encodes isoform 1. ##Evidence-Data-START## Transcript exon combination :: SRR1660809.263269.1, SRR1660807.261290.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGTCGCCG CCTGCCGCTC GGTAGCCGGG CTCCTGCCAC GCCGCCGCCG CTGCTTTCCC 
GCCCGGGCCC CGCTGCTGCG CGTCGCCCTC TGCCTCCTGT GCTGGACCCC GGCGGCTGTG 
CGCGCGGTCC CTGAGCTCGG GCTCTGGTTA GAGACAGTCA ACGACAAATC AGGACCTTTG 
ATATTTAGGA AAACTATGTT TAACTCTACA GATATCAAGT TATCTGTTAA GTCATTCCAT 
TGTTCTGGGC CTGTGAAGTT TACCATAGTG TGGCATTTGA AGTATCATAC CTGTCACAAT 
GAGCATTCTA ATCTGGAAGA GCTGTTCCAA AAACATAAAC TTAGTGTTGA TGAAGACTTT 
TGTCATTATT TGAAGAATGA CAACTGTTGG ACAACAAAAA ATGAAAACTT AGATTGCAAC 
AGTGATTCAC AGGTGTTTCC CTCTTTGAAT AATAAAGAAC TAATAAATAT CAGAAATGTT 
TCAAACCAGG AAAGATCAAT GGATGTTGTA GCCAGAACAC AAAAAGATGG GTTTCATATC 
TTTATTGTTT CTATTAAAAC GGAGAATACA GATGCAAGCT GGAATTTGAA TGTTTCTCTT 
TCTATGATTG GGCCTCATGG ATATATCTCT GCATCAGATT GGCCCCTAAT GATTTTTTAC 
ATGGTGATGT GTATTGTTTA TATATTATAT GGCATACTCT GGCTGACGTG GTCTGCCTGT 
TATTGGAAAG ATATATTAAG AATCCAGTTC TGGATTGCAG CTGTTATTTT TTTGGGAATG 
CTTGAAAAAG CAGTTTTTTA TAGTGAATAC CAAAACATCA GCAACACTGG ACTGTCAACC 
CAAGGCTTAT TGATATTTGC GGAGTTGATT TCTGCGATTA AGAGGACGTT GGCTCGCCTT 
CTCGTGATCA TTGTGAGCCT GGGCTATGGC ATTGTGAAGC CTCGTTTAGG AACAGTCATG 
CACCGGGTGA TCGGACTGGG GCTTCTATAC TTAATCTTTG CAGCTGTTGA AGGCGTGATG 
AGAGTCATTG GGGGTTCTAA CCATTTAGCT GTTGTTCTTG ATGACATTAT TTTAGCAGTT 
ATTGACTCCA TTTTTGTGTG GTTCATTTTT ATTAGTTTGG CACAAACTAT GAAGACCCTA 
AGGCTAAGAA AGAACACTGT GAAATTTTCA TTATATAGAC ATTTTAAAAA TACTCTGATC 
TTTGCTGTGC TGGCTTCTAT AGTGTTTATG GGGTGGACAA CTAAGACATT TAGAATTGCA 
AAATGCCAAT CAGATTGGAT GGAACGCTGG GTTGACGATG CATTTTGGAG CTTCCTTTTT 
TCGCTTATCC TTATTGTAAT CATGTTTTTG TGGAGACCAT CAGCAAACAA TCAGAGATAT 
GCCTTCATGC CCTTAATAGA TGATTCTGAT GATGAAATTG AGGAATTCAT GGTAACTTCT 
GAAAATTTAA CCGAAGGAAT AAAATTAAGA GCCTCAAAAT CAGTTTCCAA TGGAACAGCT 
AAGCCTGCCA CTTCTGAGAA CTTTGATGAA GATTTGAAGT GGGTAGAAGA AAATATTCCC 
TCTTCATTCA CAGATGTAGC TCTTCCAGTG TTAGTGGATT CAGATGAGGA AATCATGACC 
AGATCTGAAA TGGCTGAAAA AATGTTCTCT TCAGAAAAGA TAATGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_116213.1
CDS	370..2037
Translation	MVAACRSVAGLLPRRRRCFPARAPLLRVALCLLCWTPAAVRAVPELGLWLETVNDKSGPLIFRKTMFNSTDIKLSVKSFHCSGPVKFTIVWHLKYHTCHNEHSNLEELFQKHKLSVDEDFCHYLKNDNCWTTKNENLDCNSDSQVFPSLNNKELINIRNVSNQERSMDVVARTQKDGFHIFIVSIKTENTDASWNLNVSLSMIGPHGYISASDWPLMIFYMVMCIVYILYGILWLTWSACYWKDILRIQFWIAAVIFLGMLEKAVFYSEYQNISNTGLSTQGLLIFAELISAIKRTLARLLVIIVSLGYGIVKPRLGTVMHRVIGLGLLYLIFAAVEGVMRVIGGSNHLAVVLDDIILAVIDSIFVWFIFISLAQTMKTLRLRKNTVKFSLYRHFKNTLIFAVLASIVFMGWTTKTFRIAKCQSDWMERWVDDAFWSFLFSLILIVIMFLWRPSANNQRYAFMPLIDDSDDEIEEFMVTSENLTEGIKLRASKSVSNGTAKPATSENFDEDLKWVEENIPSSFTDVALPVLVDSDEEIMTRSEMAEKMFSSEKIM

Target ORF information:

RefSeq Version	NM_032824.2
Organism	Homo sapiens(human)
Definition	Homo sapiens transmembrane protein 87B (TMEM87B), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_032824.2

ORF Insert Sequence:

ATGGTCGCCG CCTGCCGCTC GGTAGCCGGG CTCCTGCCAC GCCGCCGCCG CTGCTTTCCC 
GCCCGGGCCC CGCTGCTGCG CGTCGCCCTC TGCCTCCTGT GCTGGACCCC GGCGGCTGTG 
CGCGCGGTCC CTGAGCTCGG GCTCTGGTTA GAGACAGTCA ACGACAAATC AGGACCTTTG 
ATATTTAGGA AAACTATGTT TAACTCTACA GATATCAAGT TATCTGTTAA GTCATTCCAT 
TGTTCTGGGC CTGTGAAGTT TACCATAGTG TGGCATTTGA AGTATCATAC CTGTCACAAT 
GAGCATTCTA ATCTGGAAGA GCTGTTCCAA AAACATAAAC TTAGTGTTGA TGAAGACTTT 
TGTCATTATT TGAAGAATGA CAACTGTTGG ACAACAAAAA ATGAAAACTT AGATTGCAAC 
AGTGATTCAC AGGTGTTTCC CTCTTTGAAT AATAAAGAAC TAATAAATAT CAGAAATGTT 
TCAAACCAGG AAAGATCAAT GGATGTTGTA GCCAGAACAC AAAAAGATGG GTTTCATATC 
TTTATTGTTT CTATTAAAAC GGAGAATACA GATGCAAGCT GGAATTTGAA TGTTTCTCTT 
TCTATGATTG GGCCTCATGG ATATATCTCT GCATCAGATT GGCCCCTAAT GATTTTTTAC 
ATGGTGATGT GTATTGTTTA TATATTATAT GGCATACTCT GGCTGACGTG GTCTGCCTGT 
TATTGGAAAG ATATATTAAG AATCCAGTTC TGGATTGCAG CTGTTATTTT TTTGGGAATG 
CTTGAAAAAG CAGTTTTTTA TAGTGAATAC CAAAACATCA GCAACACTGG ACTGTCAACC 
CAAGGCTTAT TGATATTTGC GGAGTTGATT TCTGCGATTA AGAGGACGTT GGCTCGCCTT 
CTCGTGATCA TTGTGAGCCT GGGCTATGGC ATTGTGAAGC CTCGTTTAGG AACAGTCATG 
CACCGGGTGA TCGGACTGGG GCTTCTATAC TTAATCTTTG CAGCTGTTGA AGGCGTGATG 
AGAGTCATTG GGGGTTCTAA CCATTTAGCT GTTGTTCTTG ATGACATTAT TTTAGCAGTT 
ATTGACTCCA TTTTTGTGTG GTTCATTTTT ATTAGTTTGG CACAAACTAT GAAGACCCTA 
AGGCTAAGAA AGAACACTGT GAAATTTTCA TTATATAGAC ATTTTAAAAA TACTCTGATC 
TTTGCTGTGC TGGCTTCTAT AGTGTTTATG GGGTGGACAA CTAAGACATT TAGAATTGCA 
AAATGCCAAT CAGATTGGAT GGAACGCTGG GTTGACGATG CATTTTGGAG CTTCCTTTTT 
TCGCTTATCC TTATTGTAAT CATGTTTTTG TGGAGACCAT CAGCAAACAA TCAGAGATAT 
GCCTTCATGC CCTTAATAGA TGATTCTGAT GATGAAATTG AGGAATTCAT GGTAACTTCT 
GAAAATTTAA CCGAAGGAAT AAAATTAAGA GCCTCAAAAT CAGTTTCCAA TGGAACAGCT 
AAGCCTGCCA CTTCTGAGAA CTTTGATGAA GATTTGAAGT GGGTAGAAGA AAATATTCCC 
TCTTCATTCA CAGATGTAGC TCTTCCAGTG TTAGTGGATT CAGATGAGGA AATCATGACC 
AGATCTGAAA TGGCTGAAAA AATGTTCTCT TCAGAAAAGA TAATGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TMEM87B ( NM_032824.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_116213.1 Homo sapiens transmembrane protein 87B (TMEM87B), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu10962
Clone ID Related Accession (Same CDS sequence)	NM_032824.2 , NM_032824.3
Accession Version	NM_032824.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1668bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-21
Organism	Homo sapiens(human)
Product	transmembrane protein 87B isoform 1 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA550235.1, AK027587.1, AK074243.1, AC092645.2 and AI806006.1. This sequence is a reference standard in the RefSeqGene project. On Nov 22, 2018 this sequence version replaced NM_032824.2. Transcript Variant: This variant (1) encodes isoform 1. ##Evidence-Data-START## Transcript exon combination :: SRR1660809.263269.1, SRR1660807.261290.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000283206.9/ ENSP00000283206.4 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGTCGCCG CCTGCCGCTC GGTAGCCGGG CTCCTGCCAC GCCGCCGCCG CTGCTTTCCC 
GCCCGGGCCC CGCTGCTGCG CGTCGCCCTC TGCCTCCTGT GCTGGACCCC GGCGGCTGTG 
CGCGCGGTCC CTGAGCTCGG GCTCTGGTTA GAGACAGTCA ACGACAAATC AGGACCTTTG 
ATATTTAGGA AAACTATGTT TAACTCTACA GATATCAAGT TATCTGTTAA GTCATTCCAT 
TGTTCTGGGC CTGTGAAGTT TACCATAGTG TGGCATTTGA AGTATCATAC CTGTCACAAT 
GAGCATTCTA ATCTGGAAGA GCTGTTCCAA AAACATAAAC TTAGTGTTGA TGAAGACTTT 
TGTCATTATT TGAAGAATGA CAACTGTTGG ACAACAAAAA ATGAAAACTT AGATTGCAAC 
AGTGATTCAC AGGTGTTTCC CTCTTTGAAT AATAAAGAAC TAATAAATAT CAGAAATGTT 
TCAAACCAGG AAAGATCAAT GGATGTTGTA GCCAGAACAC AAAAAGATGG GTTTCATATC 
TTTATTGTTT CTATTAAAAC GGAGAATACA GATGCAAGCT GGAATTTGAA TGTTTCTCTT 
TCTATGATTG GGCCTCATGG ATATATCTCT GCATCAGATT GGCCCCTAAT GATTTTTTAC 
ATGGTGATGT GTATTGTTTA TATATTATAT GGCATACTCT GGCTGACGTG GTCTGCCTGT 
TATTGGAAAG ATATATTAAG AATCCAGTTC TGGATTGCAG CTGTTATTTT TTTGGGAATG 
CTTGAAAAAG CAGTTTTTTA TAGTGAATAC CAAAACATCA GCAACACTGG ACTGTCAACC 
CAAGGCTTAT TGATATTTGC GGAGTTGATT TCTGCGATTA AGAGGACGTT GGCTCGCCTT 
CTCGTGATCA TTGTGAGCCT GGGCTATGGC ATTGTGAAGC CTCGTTTAGG AACAGTCATG 
CACCGGGTGA TCGGACTGGG GCTTCTATAC TTAATCTTTG CAGCTGTTGA AGGCGTGATG 
AGAGTCATTG GGGGTTCTAA CCATTTAGCT GTTGTTCTTG ATGACATTAT TTTAGCAGTT 
ATTGACTCCA TTTTTGTGTG GTTCATTTTT ATTAGTTTGG CACAAACTAT GAAGACCCTA 
AGGCTAAGAA AGAACACTGT GAAATTTTCA TTATATAGAC ATTTTAAAAA TACTCTGATC 
TTTGCTGTGC TGGCTTCTAT AGTGTTTATG GGGTGGACAA CTAAGACATT TAGAATTGCA 
AAATGCCAAT CAGATTGGAT GGAACGCTGG GTTGACGATG CATTTTGGAG CTTCCTTTTT 
TCGCTTATCC TTATTGTAAT CATGTTTTTG TGGAGACCAT CAGCAAACAA TCAGAGATAT 
GCCTTCATGC CCTTAATAGA TGATTCTGAT GATGAAATTG AGGAATTCAT GGTAACTTCT 
GAAAATTTAA CCGAAGGAAT AAAATTAAGA GCCTCAAAAT CAGTTTCCAA TGGAACAGCT 
AAGCCTGCCA CTTCTGAGAA CTTTGATGAA GATTTGAAGT GGGTAGAAGA AAATATTCCC 
TCTTCATTCA CAGATGTAGC TCTTCCAGTG TTAGTGGATT CAGATGAGGA AATCATGACC 
AGATCTGAAA TGGCTGAAAA AATGTTCTCT TCAGAAAAGA TAATGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_116213.1
CDS	324..1991
Translation	MVAACRSVAGLLPRRRRCFPARAPLLRVALCLLCWTPAAVRAVPELGLWLETVNDKSGPLIFRKTMFNSTDIKLSVKSFHCSGPVKFTIVWHLKYHTCHNEHSNLEELFQKHKLSVDEDFCHYLKNDNCWTTKNENLDCNSDSQVFPSLNNKELINIRNVSNQERSMDVVARTQKDGFHIFIVSIKTENTDASWNLNVSLSMIGPHGYISASDWPLMIFYMVMCIVYILYGILWLTWSACYWKDILRIQFWIAAVIFLGMLEKAVFYSEYQNISNTGLSTQGLLIFAELISAIKRTLARLLVIIVSLGYGIVKPRLGTVMHRVIGLGLLYLIFAAVEGVMRVIGGSNHLAVVLDDIILAVIDSIFVWFIFISLAQTMKTLRLRKNTVKFSLYRHFKNTLIFAVLASIVFMGWTTKTFRIAKCQSDWMERWVDDAFWSFLFSLILIVIMFLWRPSANNQRYAFMPLIDDSDDEIEEFMVTSENLTEGIKLRASKSVSNGTAKPATSENFDEDLKWVEENIPSSFTDVALPVLVDSDEEIMTRSEMAEKMFSSEKIM

Target ORF information:

RefSeq Version	NM_032824.3
Organism	Homo sapiens(human)
Definition	Homo sapiens transmembrane protein 87B (TMEM87B), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_032824.3

ORF Insert Sequence:

ATGGTCGCCG CCTGCCGCTC GGTAGCCGGG CTCCTGCCAC GCCGCCGCCG CTGCTTTCCC 
GCCCGGGCCC CGCTGCTGCG CGTCGCCCTC TGCCTCCTGT GCTGGACCCC GGCGGCTGTG 
CGCGCGGTCC CTGAGCTCGG GCTCTGGTTA GAGACAGTCA ACGACAAATC AGGACCTTTG 
ATATTTAGGA AAACTATGTT TAACTCTACA GATATCAAGT TATCTGTTAA GTCATTCCAT 
TGTTCTGGGC CTGTGAAGTT TACCATAGTG TGGCATTTGA AGTATCATAC CTGTCACAAT 
GAGCATTCTA ATCTGGAAGA GCTGTTCCAA AAACATAAAC TTAGTGTTGA TGAAGACTTT 
TGTCATTATT TGAAGAATGA CAACTGTTGG ACAACAAAAA ATGAAAACTT AGATTGCAAC 
AGTGATTCAC AGGTGTTTCC CTCTTTGAAT AATAAAGAAC TAATAAATAT CAGAAATGTT 
TCAAACCAGG AAAGATCAAT GGATGTTGTA GCCAGAACAC AAAAAGATGG GTTTCATATC 
TTTATTGTTT CTATTAAAAC GGAGAATACA GATGCAAGCT GGAATTTGAA TGTTTCTCTT 
TCTATGATTG GGCCTCATGG ATATATCTCT GCATCAGATT GGCCCCTAAT GATTTTTTAC 
ATGGTGATGT GTATTGTTTA TATATTATAT GGCATACTCT GGCTGACGTG GTCTGCCTGT 
TATTGGAAAG ATATATTAAG AATCCAGTTC TGGATTGCAG CTGTTATTTT TTTGGGAATG 
CTTGAAAAAG CAGTTTTTTA TAGTGAATAC CAAAACATCA GCAACACTGG ACTGTCAACC 
CAAGGCTTAT TGATATTTGC GGAGTTGATT TCTGCGATTA AGAGGACGTT GGCTCGCCTT 
CTCGTGATCA TTGTGAGCCT GGGCTATGGC ATTGTGAAGC CTCGTTTAGG AACAGTCATG 
CACCGGGTGA TCGGACTGGG GCTTCTATAC TTAATCTTTG CAGCTGTTGA AGGCGTGATG 
AGAGTCATTG GGGGTTCTAA CCATTTAGCT GTTGTTCTTG ATGACATTAT TTTAGCAGTT 
ATTGACTCCA TTTTTGTGTG GTTCATTTTT ATTAGTTTGG CACAAACTAT GAAGACCCTA 
AGGCTAAGAA AGAACACTGT GAAATTTTCA TTATATAGAC ATTTTAAAAA TACTCTGATC 
TTTGCTGTGC TGGCTTCTAT AGTGTTTATG GGGTGGACAA CTAAGACATT TAGAATTGCA 
AAATGCCAAT CAGATTGGAT GGAACGCTGG GTTGACGATG CATTTTGGAG CTTCCTTTTT 
TCGCTTATCC TTATTGTAAT CATGTTTTTG TGGAGACCAT CAGCAAACAA TCAGAGATAT 
GCCTTCATGC CCTTAATAGA TGATTCTGAT GATGAAATTG AGGAATTCAT GGTAACTTCT 
GAAAATTTAA CCGAAGGAAT AAAATTAAGA GCCTCAAAAT CAGTTTCCAA TGGAACAGCT 
AAGCCTGCCA CTTCTGAGAA CTTTGATGAA GATTTGAAGT GGGTAGAAGA AAATATTCCC 
TCTTCATTCA CAGATGTAGC TCTTCCAGTG TTAGTGGATT CAGATGAGGA AATCATGACC 
AGATCTGAAA TGGCTGAAAA AATGTTCTCT TCAGAAAAGA TAATGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TMEM87B ( NM_001329914.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001316843.1 Homo sapiens transmembrane protein 87B (TMEM87B), transcript variant 2, mRNA.

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CloneID	OHu36699
Clone ID Related Accession (Same CDS sequence)	NM_001329914.1 , NM_001329914.2
Accession Version	NM_001329914.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1668bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-06-30
Organism	Homo sapiens(human)
Product	transmembrane protein 87B isoform 2 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC093675.4 and AC092645.2. On Aug 4, 2016 this sequence version replaced XM_006712807.2. Transcript Variant: This variant (2) lacks an alternate exon and contains an additional alternate exon, compared to variant 1. It encodes isoform 2, which is of the same length, but differs in sequence, compared to isoform 1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: SRR1660803.174621.1, SRR1660809.142979.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END##

ATGGTCGCCG CCTGCCGCTC GGTAGCCGGG CTCCTGCCAC GCCGCCGCCG CTGCTTTCCC 
GCCCGGGCCC CGCTGCTGCG CGTCGCCCTC TGCCTCCTGT GCTGGACCCC GGCGGCTGTG 
CGCGCGGTCC CTGAGCTCGG GCTCTGGTTA GAGACAGTCA ACGACAAATC AGGACCTTTG 
ATATTTAGGA AAACTATGTT TAACTCTACA GATATCAAGT TATCTGTTAA GTCATTCCAT 
TGTTCTGGGC CTGTGAAGTT TACCATAGTG TGGCATTTGA AGTATCATAC CTGTCACAAT 
GAGCATTCTA ATCTGGAAGA GCTGTTCCAA AAACATAAAC TTAGTGTTGA TGAAGACTTT 
TGTCATTATT TGAAGAATGA CAACTGTTGG ACAACAAAAA ATGAAAACTT AGATTGCAAC 
AGTGATTCAC AGGTGTTTCC CTCTTTGAAT AATAAAGAAC TAATAAATAT CAGAAATGTT 
TCAAACCAGG AAAGATCAAT GGATGTTGTA GCCAGAACAC AAAAAGATGG GTTTCATATC 
TTTATTGTTT CTATTAAAAC GGAGAATACA GATGCAAGCT GGAATTTGAA TGTTTCTCTT 
TCTATGATTG GGCCTCATGG ATATATCTCT GCATCAGATT GGCCCCTAAT GATTTTTTAC 
ATGGTGATGT GTATTGTTTA TATATTATAT GGCATACTCT GGCTGACGTG GTCTGCCTGT 
TATTGGAAAG ATATATTAAG AATCCAGTTC TGGATTGCAG CTGTTATTTT TTTGGGAATG 
CTTGAAAAAG CAGTTTTTTA TAGTGAATAC CAAAACATCA GCAACACTGG ACTGTCAACC 
CAAGGCTTAT TGATATTTGC GGAGTTGATT TCTGCGATTA AGAGGACGTT GGCTCGCCTT 
CTCGTGATCA TTGTGAGCCT GGGCTATGGC ATTGTGAAGC CTCGTTTAGG AACAGTCATG 
CACCGGGTGA TCGGACTGGG GCTTCTATAC TTAATCTTTG CAGCTGTTGA AGGCGTGATG 
AGAGTCATTG GGGTGAGTGA TTCTGATCTT GTTCTTCTGG CCAGCCTCCC CCTCTCTCTC 
CTTGACTCTG GCTTGTGCTG GTGGATTTTT ATTAGTTTGG CACAAACTAT GAAGACCCTA 
AGGCTAAGAA AGAACACTGT GAAATTTTCA TTATATAGAC ATTTTAAAAA TACTCTGATC 
TTTGCTGTGC TGGCTTCTAT AGTGTTTATG GGGTGGACAA CTAAGACATT TAGAATTGCA 
AAATGCCAAT CAGATTGGAT GGAACGCTGG GTTGACGATG CATTTTGGAG CTTCCTTTTT 
TCGCTTATCC TTATTGTAAT CATGTTTTTG TGGAGACCAT CAGCAAACAA TCAGAGATAT 
GCCTTCATGC CCTTAATAGA TGATTCTGAT GATGAAATTG AGGAATTCAT GGTAACTTCT 
GAAAATTTAA CCGAAGGAAT AAAATTAAGA GCCTCAAAAT CAGTTTCCAA TGGAACAGCT 
AAGCCTGCCA CTTCTGAGAA CTTTGATGAA GATTTGAAGT GGGTAGAAGA AAATATTCCC 
TCTTCATTCA CAGATGTAGC TCTTCCAGTG TTAGTGGATT CAGATGAGGA AATCATGACC 
AGATCTGAAA TGGCTGAAAA AATGTTCTCT TCAGAAAAGA TAATGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001316843.1
CDS	370..2037
Translation	MVAACRSVAGLLPRRRRCFPARAPLLRVALCLLCWTPAAVRAVPELGLWLETVNDKSGPLIFRKTMFNSTDIKLSVKSFHCSGPVKFTIVWHLKYHTCHNEHSNLEELFQKHKLSVDEDFCHYLKNDNCWTTKNENLDCNSDSQVFPSLNNKELINIRNVSNQERSMDVVARTQKDGFHIFIVSIKTENTDASWNLNVSLSMIGPHGYISASDWPLMIFYMVMCIVYILYGILWLTWSACYWKDILRIQFWIAAVIFLGMLEKAVFYSEYQNISNTGLSTQGLLIFAELISAIKRTLARLLVIIVSLGYGIVKPRLGTVMHRVIGLGLLYLIFAAVEGVMRVIGVSDSDLVLLASLPLSLLDSGLCWWIFISLAQTMKTLRLRKNTVKFSLYRHFKNTLIFAVLASIVFMGWTTKTFRIAKCQSDWMERWVDDAFWSFLFSLILIVIMFLWRPSANNQRYAFMPLIDDSDDEIEEFMVTSENLTEGIKLRASKSVSNGTAKPATSENFDEDLKWVEENIPSSFTDVALPVLVDSDEEIMTRSEMAEKMFSSEKIM

Target ORF information:

RefSeq Version	NM_001329914.1
Organism	Homo sapiens(human)
Definition	Homo sapiens transmembrane protein 87B (TMEM87B), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001329914.1

ORF Insert Sequence:

ATGGTCGCCG CCTGCCGCTC GGTAGCCGGG CTCCTGCCAC GCCGCCGCCG CTGCTTTCCC 
GCCCGGGCCC CGCTGCTGCG CGTCGCCCTC TGCCTCCTGT GCTGGACCCC GGCGGCTGTG 
CGCGCGGTCC CTGAGCTCGG GCTCTGGTTA GAGACAGTCA ACGACAAATC AGGACCTTTG 
ATATTTAGGA AAACTATGTT TAACTCTACA GATATCAAGT TATCTGTTAA GTCATTCCAT 
TGTTCTGGGC CTGTGAAGTT TACCATAGTG TGGCATTTGA AGTATCATAC CTGTCACAAT 
GAGCATTCTA ATCTGGAAGA GCTGTTCCAA AAACATAAAC TTAGTGTTGA TGAAGACTTT 
TGTCATTATT TGAAGAATGA CAACTGTTGG ACAACAAAAA ATGAAAACTT AGATTGCAAC 
AGTGATTCAC AGGTGTTTCC CTCTTTGAAT AATAAAGAAC TAATAAATAT CAGAAATGTT 
TCAAACCAGG AAAGATCAAT GGATGTTGTA GCCAGAACAC AAAAAGATGG GTTTCATATC 
TTTATTGTTT CTATTAAAAC GGAGAATACA GATGCAAGCT GGAATTTGAA TGTTTCTCTT 
TCTATGATTG GGCCTCATGG ATATATCTCT GCATCAGATT GGCCCCTAAT GATTTTTTAC 
ATGGTGATGT GTATTGTTTA TATATTATAT GGCATACTCT GGCTGACGTG GTCTGCCTGT 
TATTGGAAAG ATATATTAAG AATCCAGTTC TGGATTGCAG CTGTTATTTT TTTGGGAATG 
CTTGAAAAAG CAGTTTTTTA TAGTGAATAC CAAAACATCA GCAACACTGG ACTGTCAACC 
CAAGGCTTAT TGATATTTGC GGAGTTGATT TCTGCGATTA AGAGGACGTT GGCTCGCCTT 
CTCGTGATCA TTGTGAGCCT GGGCTATGGC ATTGTGAAGC CTCGTTTAGG AACAGTCATG 
CACCGGGTGA TCGGACTGGG GCTTCTATAC TTAATCTTTG CAGCTGTTGA AGGCGTGATG 
AGAGTCATTG GGGTGAGTGA TTCTGATCTT GTTCTTCTGG CCAGCCTCCC CCTCTCTCTC 
CTTGACTCTG GCTTGTGCTG GTGGATTTTT ATTAGTTTGG CACAAACTAT GAAGACCCTA 
AGGCTAAGAA AGAACACTGT GAAATTTTCA TTATATAGAC ATTTTAAAAA TACTCTGATC 
TTTGCTGTGC TGGCTTCTAT AGTGTTTATG GGGTGGACAA CTAAGACATT TAGAATTGCA 
AAATGCCAAT CAGATTGGAT GGAACGCTGG GTTGACGATG CATTTTGGAG CTTCCTTTTT 
TCGCTTATCC TTATTGTAAT CATGTTTTTG TGGAGACCAT CAGCAAACAA TCAGAGATAT 
GCCTTCATGC CCTTAATAGA TGATTCTGAT GATGAAATTG AGGAATTCAT GGTAACTTCT 
GAAAATTTAA CCGAAGGAAT AAAATTAAGA GCCTCAAAAT CAGTTTCCAA TGGAACAGCT 
AAGCCTGCCA CTTCTGAGAA CTTTGATGAA GATTTGAAGT GGGTAGAAGA AAATATTCCC 
TCTTCATTCA CAGATGTAGC TCTTCCAGTG TTAGTGGATT CAGATGAGGA AATCATGACC 
AGATCTGAAA TGGCTGAAAA AATGTTCTCT TCAGAAAAGA TAATGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TMEM87B ( NM_001329914.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001316843.1 Homo sapiens transmembrane protein 87B (TMEM87B), transcript variant 2, mRNA.

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CloneID	OHu36699
Clone ID Related Accession (Same CDS sequence)	NM_001329914.1 , NM_001329914.2
Accession Version	NM_001329914.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1668bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-05-30
Organism	Homo sapiens(human)
Product	transmembrane protein 87B isoform 2 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC093675.4 and AC092645.2. On May 31, 2019 this sequence version replaced NM_001329914.1. Transcript Variant: This variant (2) lacks an alternate exon and contains an additional alternate exon, compared to variant 1. It encodes isoform 2, which is of the same length, but differs in sequence, compared to isoform 1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: SRR1660803.174621.1, SRR1660803.90339.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END##

ATGGTCGCCG CCTGCCGCTC GGTAGCCGGG CTCCTGCCAC GCCGCCGCCG CTGCTTTCCC 
GCCCGGGCCC CGCTGCTGCG CGTCGCCCTC TGCCTCCTGT GCTGGACCCC GGCGGCTGTG 
CGCGCGGTCC CTGAGCTCGG GCTCTGGTTA GAGACAGTCA ACGACAAATC AGGACCTTTG 
ATATTTAGGA AAACTATGTT TAACTCTACA GATATCAAGT TATCTGTTAA GTCATTCCAT 
TGTTCTGGGC CTGTGAAGTT TACCATAGTG TGGCATTTGA AGTATCATAC CTGTCACAAT 
GAGCATTCTA ATCTGGAAGA GCTGTTCCAA AAACATAAAC TTAGTGTTGA TGAAGACTTT 
TGTCATTATT TGAAGAATGA CAACTGTTGG ACAACAAAAA ATGAAAACTT AGATTGCAAC 
AGTGATTCAC AGGTGTTTCC CTCTTTGAAT AATAAAGAAC TAATAAATAT CAGAAATGTT 
TCAAACCAGG AAAGATCAAT GGATGTTGTA GCCAGAACAC AAAAAGATGG GTTTCATATC 
TTTATTGTTT CTATTAAAAC GGAGAATACA GATGCAAGCT GGAATTTGAA TGTTTCTCTT 
TCTATGATTG GGCCTCATGG ATATATCTCT GCATCAGATT GGCCCCTAAT GATTTTTTAC 
ATGGTGATGT GTATTGTTTA TATATTATAT GGCATACTCT GGCTGACGTG GTCTGCCTGT 
TATTGGAAAG ATATATTAAG AATCCAGTTC TGGATTGCAG CTGTTATTTT TTTGGGAATG 
CTTGAAAAAG CAGTTTTTTA TAGTGAATAC CAAAACATCA GCAACACTGG ACTGTCAACC 
CAAGGCTTAT TGATATTTGC GGAGTTGATT TCTGCGATTA AGAGGACGTT GGCTCGCCTT 
CTCGTGATCA TTGTGAGCCT GGGCTATGGC ATTGTGAAGC CTCGTTTAGG AACAGTCATG 
CACCGGGTGA TCGGACTGGG GCTTCTATAC TTAATCTTTG CAGCTGTTGA AGGCGTGATG 
AGAGTCATTG GGGTGAGTGA TTCTGATCTT GTTCTTCTGG CCAGCCTCCC CCTCTCTCTC 
CTTGACTCTG GCTTGTGCTG GTGGATTTTT ATTAGTTTGG CACAAACTAT GAAGACCCTA 
AGGCTAAGAA AGAACACTGT GAAATTTTCA TTATATAGAC ATTTTAAAAA TACTCTGATC 
TTTGCTGTGC TGGCTTCTAT AGTGTTTATG GGGTGGACAA CTAAGACATT TAGAATTGCA 
AAATGCCAAT CAGATTGGAT GGAACGCTGG GTTGACGATG CATTTTGGAG CTTCCTTTTT 
TCGCTTATCC TTATTGTAAT CATGTTTTTG TGGAGACCAT CAGCAAACAA TCAGAGATAT 
GCCTTCATGC CCTTAATAGA TGATTCTGAT GATGAAATTG AGGAATTCAT GGTAACTTCT 
GAAAATTTAA CCGAAGGAAT AAAATTAAGA GCCTCAAAAT CAGTTTCCAA TGGAACAGCT 
AAGCCTGCCA CTTCTGAGAA CTTTGATGAA GATTTGAAGT GGGTAGAAGA AAATATTCCC 
TCTTCATTCA CAGATGTAGC TCTTCCAGTG TTAGTGGATT CAGATGAGGA AATCATGACC 
AGATCTGAAA TGGCTGAAAA AATGTTCTCT TCAGAAAAGA TAATGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001316843.1
CDS	324..1991
Translation	MVAACRSVAGLLPRRRRCFPARAPLLRVALCLLCWTPAAVRAVPELGLWLETVNDKSGPLIFRKTMFNSTDIKLSVKSFHCSGPVKFTIVWHLKYHTCHNEHSNLEELFQKHKLSVDEDFCHYLKNDNCWTTKNENLDCNSDSQVFPSLNNKELINIRNVSNQERSMDVVARTQKDGFHIFIVSIKTENTDASWNLNVSLSMIGPHGYISASDWPLMIFYMVMCIVYILYGILWLTWSACYWKDILRIQFWIAAVIFLGMLEKAVFYSEYQNISNTGLSTQGLLIFAELISAIKRTLARLLVIIVSLGYGIVKPRLGTVMHRVIGLGLLYLIFAAVEGVMRVIGVSDSDLVLLASLPLSLLDSGLCWWIFISLAQTMKTLRLRKNTVKFSLYRHFKNTLIFAVLASIVFMGWTTKTFRIAKCQSDWMERWVDDAFWSFLFSLILIVIMFLWRPSANNQRYAFMPLIDDSDDEIEEFMVTSENLTEGIKLRASKSVSNGTAKPATSENFDEDLKWVEENIPSSFTDVALPVLVDSDEEIMTRSEMAEKMFSSEKIM

Target ORF information:

RefSeq Version	NM_001329914.2
Organism	Homo sapiens(human)
Definition	Homo sapiens transmembrane protein 87B (TMEM87B), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001329914.2

ORF Insert Sequence:

ATGGTCGCCG CCTGCCGCTC GGTAGCCGGG CTCCTGCCAC GCCGCCGCCG CTGCTTTCCC 
GCCCGGGCCC CGCTGCTGCG CGTCGCCCTC TGCCTCCTGT GCTGGACCCC GGCGGCTGTG 
CGCGCGGTCC CTGAGCTCGG GCTCTGGTTA GAGACAGTCA ACGACAAATC AGGACCTTTG 
ATATTTAGGA AAACTATGTT TAACTCTACA GATATCAAGT TATCTGTTAA GTCATTCCAT 
TGTTCTGGGC CTGTGAAGTT TACCATAGTG TGGCATTTGA AGTATCATAC CTGTCACAAT 
GAGCATTCTA ATCTGGAAGA GCTGTTCCAA AAACATAAAC TTAGTGTTGA TGAAGACTTT 
TGTCATTATT TGAAGAATGA CAACTGTTGG ACAACAAAAA ATGAAAACTT AGATTGCAAC 
AGTGATTCAC AGGTGTTTCC CTCTTTGAAT AATAAAGAAC TAATAAATAT CAGAAATGTT 
TCAAACCAGG AAAGATCAAT GGATGTTGTA GCCAGAACAC AAAAAGATGG GTTTCATATC 
TTTATTGTTT CTATTAAAAC GGAGAATACA GATGCAAGCT GGAATTTGAA TGTTTCTCTT 
TCTATGATTG GGCCTCATGG ATATATCTCT GCATCAGATT GGCCCCTAAT GATTTTTTAC 
ATGGTGATGT GTATTGTTTA TATATTATAT GGCATACTCT GGCTGACGTG GTCTGCCTGT 
TATTGGAAAG ATATATTAAG AATCCAGTTC TGGATTGCAG CTGTTATTTT TTTGGGAATG 
CTTGAAAAAG CAGTTTTTTA TAGTGAATAC CAAAACATCA GCAACACTGG ACTGTCAACC 
CAAGGCTTAT TGATATTTGC GGAGTTGATT TCTGCGATTA AGAGGACGTT GGCTCGCCTT 
CTCGTGATCA TTGTGAGCCT GGGCTATGGC ATTGTGAAGC CTCGTTTAGG AACAGTCATG 
CACCGGGTGA TCGGACTGGG GCTTCTATAC TTAATCTTTG CAGCTGTTGA AGGCGTGATG 
AGAGTCATTG GGGTGAGTGA TTCTGATCTT GTTCTTCTGG CCAGCCTCCC CCTCTCTCTC 
CTTGACTCTG GCTTGTGCTG GTGGATTTTT ATTAGTTTGG CACAAACTAT GAAGACCCTA 
AGGCTAAGAA AGAACACTGT GAAATTTTCA TTATATAGAC ATTTTAAAAA TACTCTGATC 
TTTGCTGTGC TGGCTTCTAT AGTGTTTATG GGGTGGACAA CTAAGACATT TAGAATTGCA 
AAATGCCAAT CAGATTGGAT GGAACGCTGG GTTGACGATG CATTTTGGAG CTTCCTTTTT 
TCGCTTATCC TTATTGTAAT CATGTTTTTG TGGAGACCAT CAGCAAACAA TCAGAGATAT 
GCCTTCATGC CCTTAATAGA TGATTCTGAT GATGAAATTG AGGAATTCAT GGTAACTTCT 
GAAAATTTAA CCGAAGGAAT AAAATTAAGA GCCTCAAAAT CAGTTTCCAA TGGAACAGCT 
AAGCCTGCCA CTTCTGAGAA CTTTGATGAA GATTTGAAGT GGGTAGAAGA AAATATTCCC 
TCTTCATTCA CAGATGTAGC TCTTCCAGTG TTAGTGGATT CAGATGAGGA AATCATGACC 
AGATCTGAAA TGGCTGAAAA AATGTTCTCT TCAGAAAAGA TAATGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TMEM87B ( XM_017005121.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016860610.1 Homo sapiens transmembrane protein 87B (TMEM87B), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu90001
Clone ID Related Accession (Same CDS sequence)	XM_017005121.1
Accession Version	XM_017005121.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1065bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	transmembrane protein 87B isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000002.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGATTGGGC CTCATGGATA TATCTCTGCA TCAGATTGGC CCCTAATGAT TTTTTACATG 
GTGATGTGTA TTGTTTATAT ATTATATGGC ATACTCTGGC TGACGTGGTC TGCCTGTTAT 
TGGAAAGATA TATTAAGAAT CCAGTTCTGG ATTGCAGCTG TTATTTTTTT GGGAATGCTT 
GAAAAAGCAG TTTTTTATAG TGAATACCAA AACATCAGCA ACACTGGACT GTCAACCCAA 
GGCTTATTGA TATTTGCGGA GTTGATTTCT GCGATTAAGA GGACGTTGGC TCGCCTTCTC 
GTGATCATTG TGAGCCTGGG CTATGGCATT GTGAAGCCTC GTTTAGGAAC AGTCATGCAC 
CGGGTGATCG GACTGGGGCT TCTATACTTA ATCTTTGCAG CTGTTGAAGG CGTGATGAGA 
GTCATTGGGG GTTCTAACCA TTTAGCTGTT GTTCTTGATG ACATTATTTT AGCAGTTATT 
GACTCCATTT TTGTGTGGTT CATTTTTATT AGTTTGGCAC AAACTATGAA GACCCTAAGG 
CTAAGAAAGA ACACTGTGAA ATTTTCATTA TATAGACATT TTAAAAATAC TCTGATCTTT 
GCTGTGCTGG CTTCTATAGT GTTTATGGGG TGGACAACTA AGACATTTAG AATTGCAAAA 
TGCCAATCAG ATTGGATGGA ACGCTGGGTT GACGATGCAT TTTGGAGCTT CCTTTTTTCG 
CTTATCCTTA TTGTAATCAT GTTTTTGTGG AGACCATCAG CAAACAATCA GAGATATGCC 
TTCATGCCCT TAATAGATGA TTCTGATGAT GAAATTGAGG AATTCATGGT AACTTCTGAA 
AATTTAACCG AAGGAATAAA ATTAAGAGCC TCAAAATCAG TTTCCAATGG AACAGCTAAG 
CCTGCCACTT CTGAGAACTT TGATGAAGAT TTGAAGTGGG TAGAAGAAAA TATTCCCTCT 
TCATTCACAG ATGTAGCTCT TCCAGTGTTA GTGGATTCAG ATGAGGAAAT CATGACCAGA 
TCTGAAATGG CTGAAAAAAT GTTCTCTTCA GAAAAGATAA TGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016860610.1
CDS	334..1398
Translation	MIGPHGYISASDWPLMIFYMVMCIVYILYGILWLTWSACYWKDILRIQFWIAAVIFLGMLEKAVFYSEYQNISNTGLSTQGLLIFAELISAIKRTLARLLVIIVSLGYGIVKPRLGTVMHRVIGLGLLYLIFAAVEGVMRVIGGSNHLAVVLDDIILAVIDSIFVWFIFISLAQTMKTLRLRKNTVKFSLYRHFKNTLIFAVLASIVFMGWTTKTFRIAKCQSDWMERWVDDAFWSFLFSLILIVIMFLWRPSANNQRYAFMPLIDDSDDEIEEFMVTSENLTEGIKLRASKSVSNGTAKPATSENFDEDLKWVEENIPSSFTDVALPVLVDSDEEIMTRSEMAEKMFSSEKIM

Target ORF information:

RefSeq Version	XM_017005121.1
Organism	Homo sapiens(human)
Definition	Homo sapiens transmembrane protein 87B (TMEM87B), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017005121.1

ORF Insert Sequence:

ATGATTGGGC CTCATGGATA TATCTCTGCA TCAGATTGGC CCCTAATGAT TTTTTACATG 
GTGATGTGTA TTGTTTATAT ATTATATGGC ATACTCTGGC TGACGTGGTC TGCCTGTTAT 
TGGAAAGATA TATTAAGAAT CCAGTTCTGG ATTGCAGCTG TTATTTTTTT GGGAATGCTT 
GAAAAAGCAG TTTTTTATAG TGAATACCAA AACATCAGCA ACACTGGACT GTCAACCCAA 
GGCTTATTGA TATTTGCGGA GTTGATTTCT GCGATTAAGA GGACGTTGGC TCGCCTTCTC 
GTGATCATTG TGAGCCTGGG CTATGGCATT GTGAAGCCTC GTTTAGGAAC AGTCATGCAC 
CGGGTGATCG GACTGGGGCT TCTATACTTA ATCTTTGCAG CTGTTGAAGG CGTGATGAGA 
GTCATTGGGG GTTCTAACCA TTTAGCTGTT GTTCTTGATG ACATTATTTT AGCAGTTATT 
GACTCCATTT TTGTGTGGTT CATTTTTATT AGTTTGGCAC AAACTATGAA GACCCTAAGG 
CTAAGAAAGA ACACTGTGAA ATTTTCATTA TATAGACATT TTAAAAATAC TCTGATCTTT 
GCTGTGCTGG CTTCTATAGT GTTTATGGGG TGGACAACTA AGACATTTAG AATTGCAAAA 
TGCCAATCAG ATTGGATGGA ACGCTGGGTT GACGATGCAT TTTGGAGCTT CCTTTTTTCG 
CTTATCCTTA TTGTAATCAT GTTTTTGTGG AGACCATCAG CAAACAATCA GAGATATGCC 
TTCATGCCCT TAATAGATGA TTCTGATGAT GAAATTGAGG AATTCATGGT AACTTCTGAA 
AATTTAACCG AAGGAATAAA ATTAAGAGCC TCAAAATCAG TTTCCAATGG AACAGCTAAG 
CCTGCCACTT CTGAGAACTT TGATGAAGAT TTGAAGTGGG TAGAAGAAAA TATTCCCTCT 
TCATTCACAG ATGTAGCTCT TCCAGTGTTA GTGGATTCAG ATGAGGAAAT CATGACCAGA 
TCTGAAATGG CTGAAAAAAT GTTCTCTTCA GAAAAGATAA TGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Discovery of a potentially deleterious variant in TMEM87B in a patient with a hemizygous 2q13 microdeletion suggests a recessive condition characterized by congenital heart disease and restrictive cardiomyopathy.
Cold Spring Harbor molecular case studies2(3)a000844(2016 May)
Yu HC,Coughlin CR,Geiger EA,Salvador BJ,Elias ER,Cavanaugh JL,Chatfield KC,Miyamoto SD,Shaikh TH

Recurrent deletions and duplications of chromosome 2q11.2 and 2q13 are associated with variable outcomes.
American journal of medical genetics. Part A167A(11)2664-73(2015 Nov)
Riley KN,Catalano LM,Bernat JA,Adams SD,Martin DM,Lalani SR,Patel A,Burnside RD,Innis JW,Rudd MK

Post-Golgi anterograde transport requires GARP-dependent endosome-to-TGN retrograde transport.
Molecular biology of the cell26(17)3071-84(2015 Sep)
Hirata T,Fujita M,Nakamura S,Gotoh K,Motooka D,Murakami Y,Maeda Y,Kinoshita T

A recurrent deletion on chromosome 2q13 is associated with developmental delay and mild facial dysmorphisms.
Molecular cytogenetics857(2015)
Hladilkova E,Bar?y T,Fannemel M,Vallova V,Misceo D,Bryn V,Slamova I,Prasilova S,Kuglik P,Frengen E

Functional analysis of candidate genes in 2q13 deletion syndrome implicates FBLN7 and TMEM87B deficiency in congenital heart defects and FBLN7 in craniofacial malformations.
Human molecular genetics23(16)4272-84(2014 Aug)
Russell MW,Raeker MO,Geisler SB,Thomas PE,Simmons TA,Bernat JA,Thorsson T,Innis JW

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TMEM87B cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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