SLC7A3 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	SLC7A3
Entrez Gene ID	84889
Full Name	solute carrier family 7 member 3
Synonyms	ATRC3,CAT-3,CAT3
General protein information	Preferred Names solute carrier family 7 member 3 Names cationic amino acid transporter 3 solute carrier family 7 (cationic amino acid transporter, y+ system), member 3
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: X Map Location: Xq13.1
Summary	This gene encodes a member of the solute carrier family 7. The encoded protein is a sodium-independent cationic amino acid transporter. Alternate splicing results in multiple transcripts that encoded the same protein.[provided by RefSeq, May 2010].
Disorder MIM:	300443

mRNA and Protein(s)

mRNA	Protein	Name
XM_017029912.1	XP_016885401.1	cationic amino acid transporter 3 isoform X1
NM_001048164.3	NP_001041629.1	cationic amino acid transporter 3
NM_032803.5	NP_116192.4	cationic amino acid transporter 3
NM_001048164.2	NP_001041629.1	cationic amino acid transporter 3
NM_032803.6	NP_116192.4	cationic amino acid transporter 3

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	SLC7A3	XP_003954575.1
Gallus gallus (chicken)	SLC7A3	XP_420204.4
Danio rerio (zebrafish)	slc7a3a	NP_001007330.2
Danio rerio (zebrafish)	LOC100003376	XP_001342962.2
Homo sapiens (human)	SLC7A3	NP_001041629.1
Bos taurus (cattle)	SLC7A3	NP_001071487.1
Mus musculus (house mouse)	Slc7a3	NP_031541.1
Rattus norvegicus (Norway rat)	Slc7a3	NP_058913.1
Oryza sativa (rice)	Os10g0437100	NP_001064675.1
Canis lupus familiaris (dog)	SLC7A3	XP_005641511.1

Gene Ontology
Bibliography

Related articles in PubMed

Hypomorphic variants of cationic amino acid transporter 3 in males with autism spectrum disorders.
Nava C, Rupp J, Boissel JP, Mignot C, Rastetter A, Amiet C, Jacquette A, Dupuits C, Bouteiller D, Keren B, Ruberg M, Faudet A, Doummar D, Philippe A, P?risse D, Laurent C, Lebrun N, Guillemot V, Chelly J, Cohen D, H?ron D, Brice A, Closs EI, Depienne C
Amino acids47(12)2647-58(2015 Dec)

Genetic ablation of solute carrier family 7a3a leads to hepatic steatosis in zebrafish during fasting.
Gu Q, Yang X, Lin L, Li S, Li Q, Zhong S, Peng J, Cui Z
Hepatology (Baltimore, Md.)60(6)1929-41(2014 Dec)

Differential topochemistry of three cationic amino acid transporter proteins, hCAT1, hCAT2 and hCAT3, in the adult human brain.
J?ger K, Wolf S, Dobrowolny H, Steiner J, Nave H, Maronde E, Bogerts B, Bernstein HG
Amino acids44(2)423-33(2013 Feb)

Activation of classical protein kinase C reduces the expression of human cationic amino acid transporter 3 (hCAT-3) in the plasma membrane.
Rotmann A, V?kony N, Gassner D, Niegisch G, Strand D, Martin? U, Closs EI
The Biochemical journal395(1)117-23(2006 Apr)

Monovalent cation conductance in Xenopus laevis oocytes expressing hCAT-3.
Gilles W, Vulcu SD, Liewald JF, Habermeier A, V?kony N, Closs EI, Rupp J, Nawrath H
Biochimica et biophysica acta1668(2)234-9(2005 Mar)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

rare hypomorphic variants of SLC7A3 exist in male individuals, SLC7A3 variants possibly contribute to the etiology of autism spectrum disorders in male subjects in association with other genetic factors
Title: Hypomorphic variants of cationic amino acid transporter 3 in males with autism spectrum disorders.

knockdown impaired AMPK-PPAR-alpha signaling and resulted in lipid accumulation under glucose starvation in liver cells
Title: Genetic ablation of solute carrier family 7a3a leads to hepatic steatosis in zebrafish during fasting.

CAT1, CAT2, and CAT3 localized in adult brains but with uneven distribution.
Title: Differential topochemistry of three cationic amino acid transporter proteins, hCAT1, hCAT2 and hCAT3, in the adult human brain.

It is concluded that similar to hCAT-1, hCAT-3 activity is decreased by PKC via reduction of transporter molecules in the plasma membrane.
Title: Activation of classical protein kinase C reduces the expression of human cationic amino acid transporter 3 (hCAT-3) in the plasma membrane.

is concluded that hCAT-3 is a passive transport system that conducts monovalent cations including L-Arg.
Title: Monovalent cation conductance in Xenopus laevis oocytes expressing hCAT-3.

The following SLC7A3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the SLC7A3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu21460	NM_001048164.3 Latest version!	Homo sapiens solute carrier family 7 member 3 (SLC7A3), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
OHu21460	NM_032803.6 Latest version!	Homo sapiens solute carrier family 7 member 3 (SLC7A3), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
OHu21460	XM_017029912.1 Latest version!	Homo sapiens solute carrier family 7 member 3 (SLC7A3), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
View Old Accession Versions >>
OHu21460	NM_001048164.2	Homo sapiens solute carrier family 7 member 3 (SLC7A3), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
OHu21460	NM_032803.5	Homo sapiens solute carrier family 7 member 3 (SLC7A3), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
Hide Old Accession Versions >>

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***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

SLC7A3 ( NM_001048164.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_001041629.1 Homo sapiens solute carrier family 7 member 3 (SLC7A3), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu21460
Clone ID Related Accession (Same CDS sequence)	XM_017029912.1 , NM_001048164.3 , NM_032803.5 , NM_001048164.2 , NM_032803.6
Accession Version	NM_001048164.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1860bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-27
Organism	Homo sapiens(human)
Product	cationic amino acid transporter 3
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK075014.1 and BC033816.1. On May 31, 2019 this sequence version replaced NM_001048164.2. Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Both variants 1 and 2 encode the same protein. ##Evidence-Data-START## Transcript exon combination :: SRR1660803.141247.1, AK075014.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2155974, SAMEA2156099 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCCGTGGC AAGCATTTCG CAGATTTGGT CAAAAGCTGG TACGCAGACG TACACTGGAG 
TCAGGCATGG CTGAGACTCG CCTTGCCAGA TGCCTAAGCA CCCTGGATTT AGTGGCCCTG 
GGTGTGGGCA GCACATTGGG TGCAGGCGTG TATGTCCTAG CTGGCGAGGT GGCCAAAGAT 
AAAGCAGGGC CATCCATTGT GATCTGCTTT TTGGTGGCTG CCCTGTCTTC TGTGTTGGCT 
GGGCTGTGCT ATGCGGAGTT TGGTGCCCGG GTTCCCCGTT CTGGTTCGGC ATATCTCTAC 
AGCTATGTCA CTGTGGGTGA ACTCTGGGCC TTCACCACTG GCTGGAACCT CATCCTCTCC 
TATGTCATTG GTACAGCCAG TGTGGCCCGG GCCTGGAGCT CTGCTTTTGA CAACCTGATT 
GGGAACCACA TCTCTAAGAC TCTGCAGGGG TCCATTGCAC TGCACGTGCC CCATGTCCTT 
GCAGAATATC CAGATTTCTT TGCTTTGGGC CTCGTGTTGC TGCTCACTGG ATTGTTGGCT 
CTCGGGGCTA GTGAGTCGGC CCTGGTTACC AAAGTGTTCA CAGGCGTGAA CCTTTTGGTT 
CTTGGGTTCG TCATGATCTC TGGCTTCGTT AAGGGGGACG TGCACAACTG GAAGCTCACA 
GAAGAGGACT ACGAATTGGC CATGGCTGAA CTCAATGACA CCTATAGCTT GGGTCCTCTG 
GGCTCTGGAG GATTTGTGCC TTTCGGCTTC GAGGGAATTC TCCGTGGAGC AGCGACCTGT 
TTCTATGCAT TTGTTGGTTT CGACTGTATT GCTACCACTG GAGAAGAAGC CCAGAATCCC 
CAGCGTTCCA TCCCGATGGG CATTGTGATC TCACTGTCTG TCTGCTTTTT GGCGTATTTT 
GCTGTCTCTT CTGCACTCAC CCTGATGATG CCTTACTACC AGCTTCAGCC TGAGAGCCCT 
TTGCCTGAGG CATTTCTCTA CATTGGATGG GCTCCTGCCC GCTATGTTGT GGCTGTTGGC 
TCCCTCTGTG CTCTTTCTAC CAGCCTCCTG GGCTCCATGT TCCCCATGCC TCGGGTGATC 
TACGCGATGG CAGAGGATGG CCTCCTGTTC CGTGTACTTG CTCGGATCCA CACCGGCACA 
CGCACCCCAA TCATAGCCAC CGTGGTCTCT GGCATTATTG CAGCATTCAT GGCATTCCTC 
TTCAAACTCA CTGATCTTGT GGACCTCATG TCAATTGGGA CCCTGCTTGC TTACTCCCTG 
GTGTCGATTT GTGTTCTCAT CCTCAGGTAT CAACCTGATC AGGAGACAAA GACTGGGGAA 
GAAGTGGAGT TGCAGGAGGA GGCAATAACT ACTGAATCAG AGAAGTTGAC CCTATGGGGA 
CTATTTTTCC CACTCAACTC CATCCCCACT CCACTCTCTG GCCAAATTGT CTATGTTTGT 
TCCTCATTGC TTGCTGTCCT GCTGACTGCT CTTTGCCTGG TGCTGGCCCA GTGGTCAGTT 
CCATTGCTTT CTGGAGACCT GCTGTGGACT GCAGTGGTTG TGCTGCTCCT GCTGCTCATT 
ATTGGGATCA TTGTGGTCAT CTGGAGACAG CCACAGAGTT CCACTCCCCT TCACTTTAAG 
GTGCCTGCTT TGCCTCTCCT CCCACTAATG AGCATCTTTG TGAATATTTA CCTTATGATG 
CAGATGACAG CTGGTACCTG GGCCCGATTT GGGGTCTGGA TGCTGATTGG CTTTGCTATC 
TACTTCGGCT ATGGGATCCA GCACAGCCTG GAAGAGATTA AGAGTAACCA ACCCTCACGC 
AAGTCTAGAG CCAAAACTGT AGACCTTGAT CCCGGCACTC TCTATGTCCA CTCAGTTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001041629.1
CDS	122..1981
Translation	MPWQAFRRFGQKLVRRRTLESGMAETRLARCLSTLDLVALGVGSTLGAGVYVLAGEVAKDKAGPSIVICFLVAALSSVLAGLCYAEFGARVPRSGSAYLYSYVTVGELWAFTTGWNLILSYVIGTASVARAWSSAFDNLIGNHISKTLQGSIALHVPHVLAEYPDFFALGLVLLLTGLLALGASESALVTKVFTGVNLLVLGFVMISGFVKGDVHNWKLTEEDYELAMAELNDTYSLGPLGSGGFVPFGFEGILRGAATCFYAFVGFDCIATTGEEAQNPQRSIPMGIVISLSVCFLAYFAVSSALTLMMPYYQLQPESPLPEAFLYIGWAPARYVVAVGSLCALSTSLLGSMFPMPRVIYAMAEDGLLFRVLARIHTGTRTPIIATVVSGIIAAFMAFLFKLTDLVDLMSIGTLLAYSLVSICVLILRYQPDQETKTGEEVELQEEAITTESEKLTLWGLFFPLNSIPTPLSGQIVYVCSSLLAVLLTALCLVLAQWSVPLLSGDLLWTAVVVLLLLLIIGIIVVIWRQPQSSTPLHFKVPALPLLPLMSIFVNIYLMMQMTAGTWARFGVWMLIGFAIYFGYGIQHSLEEIKSNQPSRKSRAKTVDLDPGTLYVHSV

Target ORF information:

RefSeq Version	NM_001048164.3
Organism	Homo sapiens(human)
Definition	Homo sapiens solute carrier family 7 member 3 (SLC7A3), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001048164.3

ORF Insert Sequence:

ATGCCGTGGC AAGCATTTCG CAGATTTGGT CAAAAGCTGG TACGCAGACG TACACTGGAG 
TCAGGCATGG CTGAGACTCG CCTTGCCAGA TGCCTAAGCA CCCTGGATTT AGTGGCCCTG 
GGTGTGGGCA GCACATTGGG TGCAGGCGTG TATGTCCTAG CTGGCGAGGT GGCCAAAGAT 
AAAGCAGGGC CATCCATTGT GATCTGCTTT TTGGTGGCTG CCCTGTCTTC TGTGTTGGCT 
GGGCTGTGCT ATGCGGAGTT TGGTGCCCGG GTTCCCCGTT CTGGTTCGGC ATATCTCTAC 
AGCTATGTCA CTGTGGGTGA ACTCTGGGCC TTCACCACTG GCTGGAACCT CATCCTCTCC 
TATGTCATTG GTACAGCCAG TGTGGCCCGG GCCTGGAGCT CTGCTTTTGA CAACCTGATT 
GGGAACCACA TCTCTAAGAC TCTGCAGGGG TCCATTGCAC TGCACGTGCC CCATGTCCTT 
GCAGAATATC CAGATTTCTT TGCTTTGGGC CTCGTGTTGC TGCTCACTGG ATTGTTGGCT 
CTCGGGGCTA GTGAGTCGGC CCTGGTTACC AAAGTGTTCA CAGGCGTGAA CCTTTTGGTT 
CTTGGGTTCG TCATGATCTC TGGCTTCGTT AAGGGGGACG TGCACAACTG GAAGCTCACA 
GAAGAGGACT ACGAATTGGC CATGGCTGAA CTCAATGACA CCTATAGCTT GGGTCCTCTG 
GGCTCTGGAG GATTTGTGCC TTTCGGCTTC GAGGGAATTC TCCGTGGAGC AGCGACCTGT 
TTCTATGCAT TTGTTGGTTT CGACTGTATT GCTACCACTG GAGAAGAAGC CCAGAATCCC 
CAGCGTTCCA TCCCGATGGG CATTGTGATC TCACTGTCTG TCTGCTTTTT GGCGTATTTT 
GCTGTCTCTT CTGCACTCAC CCTGATGATG CCTTACTACC AGCTTCAGCC TGAGAGCCCT 
TTGCCTGAGG CATTTCTCTA CATTGGATGG GCTCCTGCCC GCTATGTTGT GGCTGTTGGC 
TCCCTCTGTG CTCTTTCTAC CAGCCTCCTG GGCTCCATGT TCCCCATGCC TCGGGTGATC 
TACGCGATGG CAGAGGATGG CCTCCTGTTC CGTGTACTTG CTCGGATCCA CACCGGCACA 
CGCACCCCAA TCATAGCCAC CGTGGTCTCT GGCATTATTG CAGCATTCAT GGCATTCCTC 
TTCAAACTCA CTGATCTTGT GGACCTCATG TCAATTGGGA CCCTGCTTGC TTACTCCCTG 
GTGTCGATTT GTGTTCTCAT CCTCAGGTAT CAACCTGATC AGGAGACAAA GACTGGGGAA 
GAAGTGGAGT TGCAGGAGGA GGCAATAACT ACTGAATCAG AGAAGTTGAC CCTATGGGGA 
CTATTTTTCC CACTCAACTC CATCCCCACT CCACTCTCTG GCCAAATTGT CTATGTTTGT 
TCCTCATTGC TTGCTGTCCT GCTGACTGCT CTTTGCCTGG TGCTGGCCCA GTGGTCAGTT 
CCATTGCTTT CTGGAGACCT GCTGTGGACT GCAGTGGTTG TGCTGCTCCT GCTGCTCATT 
ATTGGGATCA TTGTGGTCAT CTGGAGACAG CCACAGAGTT CCACTCCCCT TCACTTTAAG 
GTGCCTGCTT TGCCTCTCCT CCCACTAATG AGCATCTTTG TGAATATTTA CCTTATGATG 
CAGATGACAG CTGGTACCTG GGCCCGATTT GGGGTCTGGA TGCTGATTGG CTTTGCTATC 
TACTTCGGCT ATGGGATCCA GCACAGCCTG GAAGAGATTA AGAGTAACCA ACCCTCACGC 
AAGTCTAGAG CCAAAACTGT AGACCTTGAT CCCGGCACTC TCTATGTCCA CTCAGTTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SLC7A3 ( NM_032803.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_116192.4 Homo sapiens solute carrier family 7 member 3 (SLC7A3), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu21460
Clone ID Related Accession (Same CDS sequence)	XM_017029912.1 , NM_001048164.3 , NM_032803.5 , NM_001048164.2 , NM_032803.6
Accession Version	NM_032803.5	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1860bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-01
Organism	Homo sapiens(human)
Product	cationic amino acid transporter 3
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK075014.1, AK074865.1, AL627071.16 and BC033816.1. This sequence is a reference standard in the RefSeqGene project. On May 26, 2010 this sequence version replaced NM_032803.4. Transcript Variant: This variant (1) represents the longer transcript. Both variants 1 and 2 encode the same protein. ##Evidence-Data-START## Transcript exon combination :: BC033816.1, AK074865.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968189, SAMEA2145743 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCCGTGGC AAGCATTTCG CAGATTTGGT CAAAAGCTGG TACGCAGACG TACACTGGAG 
TCAGGCATGG CTGAGACTCG CCTTGCCAGA TGCCTAAGCA CCCTGGATTT AGTGGCCCTG 
GGTGTGGGCA GCACATTGGG TGCAGGCGTG TATGTCCTAG CTGGCGAGGT GGCCAAAGAT 
AAAGCAGGGC CATCCATTGT GATCTGCTTT TTGGTGGCTG CCCTGTCTTC TGTGTTGGCT 
GGGCTGTGCT ATGCGGAGTT TGGTGCCCGG GTTCCCCGTT CTGGTTCGGC ATATCTCTAC 
AGCTATGTCA CTGTGGGTGA ACTCTGGGCC TTCACCACTG GCTGGAACCT CATCCTCTCC 
TATGTCATTG GTACAGCCAG TGTGGCCCGG GCCTGGAGCT CTGCTTTTGA CAACCTGATT 
GGGAACCACA TCTCTAAGAC TCTGCAGGGG TCCATTGCAC TGCACGTGCC CCATGTCCTT 
GCAGAATATC CAGATTTCTT TGCTTTGGGC CTCGTGTTGC TGCTCACTGG ATTGTTGGCT 
CTCGGGGCTA GTGAGTCGGC CCTGGTTACC AAAGTGTTCA CAGGCGTGAA CCTTTTGGTT 
CTTGGGTTCG TCATGATCTC TGGCTTCGTT AAGGGGGACG TGCACAACTG GAAGCTCACA 
GAAGAGGACT ACGAATTGGC CATGGCTGAA CTCAATGACA CCTATAGCTT GGGTCCTCTG 
GGCTCTGGAG GATTTGTGCC TTTCGGCTTC GAGGGAATTC TCCGTGGAGC AGCGACCTGT 
TTCTATGCAT TTGTTGGTTT CGACTGTATT GCTACCACTG GAGAAGAAGC CCAGAATCCC 
CAGCGTTCCA TCCCGATGGG CATTGTGATC TCACTGTCTG TCTGCTTTTT GGCGTATTTT 
GCTGTCTCTT CTGCACTCAC CCTGATGATG CCTTACTACC AGCTTCAGCC TGAGAGCCCT 
TTGCCTGAGG CATTTCTCTA CATTGGATGG GCTCCTGCCC GCTATGTTGT GGCTGTTGGC 
TCCCTCTGTG CTCTTTCTAC CAGCCTCCTG GGCTCCATGT TCCCCATGCC TCGGGTGATC 
TACGCGATGG CAGAGGATGG CCTCCTGTTC CGTGTACTTG CTCGGATCCA CACCGGCACA 
CGCACCCCAA TCATAGCCAC CGTGGTCTCT GGCATTATTG CAGCATTCAT GGCATTCCTC 
TTCAAACTCA CTGATCTTGT GGACCTCATG TCAATTGGGA CCCTGCTTGC TTACTCCCTG 
GTGTCGATTT GTGTTCTCAT CCTCAGGTAT CAACCTGATC AGGAGACAAA GACTGGGGAA 
GAAGTGGAGT TGCAGGAGGA GGCAATAACT ACTGAATCAG AGAAGTTGAC CCTATGGGGA 
CTATTTTTCC CACTCAACTC CATCCCCACT CCACTCTCTG GCCAAATTGT CTATGTTTGT 
TCCTCATTGC TTGCTGTCCT GCTGACTGCT CTTTGCCTGG TGCTGGCCCA GTGGTCAGTT 
CCATTGCTTT CTGGAGACCT GCTGTGGACT GCAGTGGTTG TGCTGCTCCT GCTGCTCATT 
ATTGGGATCA TTGTGGTCAT CTGGAGACAG CCACAGAGTT CCACTCCCCT TCACTTTAAG 
GTGCCTGCTT TGCCTCTCCT CCCACTAATG AGCATCTTTG TGAATATTTA CCTTATGATG 
CAGATGACAG CTGGTACCTG GGCCCGATTT GGGGTCTGGA TGCTGATTGG CTTTGCTATC 
TACTTCGGCT ATGGGATCCA GCACAGCCTG GAAGAGATTA AGAGTAACCA ACCCTCACGC 
AAGTCTAGAG CCAAAACTGT AGACCTTGAT CCCGGCACTC TCTATGTCCA CTCAGTTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_116192.4
CDS	175..2034
Translation	MPWQAFRRFGQKLVRRRTLESGMAETRLARCLSTLDLVALGVGSTLGAGVYVLAGEVAKDKAGPSIVICFLVAALSSVLAGLCYAEFGARVPRSGSAYLYSYVTVGELWAFTTGWNLILSYVIGTASVARAWSSAFDNLIGNHISKTLQGSIALHVPHVLAEYPDFFALGLVLLLTGLLALGASESALVTKVFTGVNLLVLGFVMISGFVKGDVHNWKLTEEDYELAMAELNDTYSLGPLGSGGFVPFGFEGILRGAATCFYAFVGFDCIATTGEEAQNPQRSIPMGIVISLSVCFLAYFAVSSALTLMMPYYQLQPESPLPEAFLYIGWAPARYVVAVGSLCALSTSLLGSMFPMPRVIYAMAEDGLLFRVLARIHTGTRTPIIATVVSGIIAAFMAFLFKLTDLVDLMSIGTLLAYSLVSICVLILRYQPDQETKTGEEVELQEEAITTESEKLTLWGLFFPLNSIPTPLSGQIVYVCSSLLAVLLTALCLVLAQWSVPLLSGDLLWTAVVVLLLLLIIGIIVVIWRQPQSSTPLHFKVPALPLLPLMSIFVNIYLMMQMTAGTWARFGVWMLIGFAIYFGYGIQHSLEEIKSNQPSRKSRAKTVDLDPGTLYVHSV

Target ORF information:

RefSeq Version	NM_032803.5
Organism	Homo sapiens(human)
Definition	Homo sapiens solute carrier family 7 member 3 (SLC7A3), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_032803.5

ORF Insert Sequence:

ATGCCGTGGC AAGCATTTCG CAGATTTGGT CAAAAGCTGG TACGCAGACG TACACTGGAG 
TCAGGCATGG CTGAGACTCG CCTTGCCAGA TGCCTAAGCA CCCTGGATTT AGTGGCCCTG 
GGTGTGGGCA GCACATTGGG TGCAGGCGTG TATGTCCTAG CTGGCGAGGT GGCCAAAGAT 
AAAGCAGGGC CATCCATTGT GATCTGCTTT TTGGTGGCTG CCCTGTCTTC TGTGTTGGCT 
GGGCTGTGCT ATGCGGAGTT TGGTGCCCGG GTTCCCCGTT CTGGTTCGGC ATATCTCTAC 
AGCTATGTCA CTGTGGGTGA ACTCTGGGCC TTCACCACTG GCTGGAACCT CATCCTCTCC 
TATGTCATTG GTACAGCCAG TGTGGCCCGG GCCTGGAGCT CTGCTTTTGA CAACCTGATT 
GGGAACCACA TCTCTAAGAC TCTGCAGGGG TCCATTGCAC TGCACGTGCC CCATGTCCTT 
GCAGAATATC CAGATTTCTT TGCTTTGGGC CTCGTGTTGC TGCTCACTGG ATTGTTGGCT 
CTCGGGGCTA GTGAGTCGGC CCTGGTTACC AAAGTGTTCA CAGGCGTGAA CCTTTTGGTT 
CTTGGGTTCG TCATGATCTC TGGCTTCGTT AAGGGGGACG TGCACAACTG GAAGCTCACA 
GAAGAGGACT ACGAATTGGC CATGGCTGAA CTCAATGACA CCTATAGCTT GGGTCCTCTG 
GGCTCTGGAG GATTTGTGCC TTTCGGCTTC GAGGGAATTC TCCGTGGAGC AGCGACCTGT 
TTCTATGCAT TTGTTGGTTT CGACTGTATT GCTACCACTG GAGAAGAAGC CCAGAATCCC 
CAGCGTTCCA TCCCGATGGG CATTGTGATC TCACTGTCTG TCTGCTTTTT GGCGTATTTT 
GCTGTCTCTT CTGCACTCAC CCTGATGATG CCTTACTACC AGCTTCAGCC TGAGAGCCCT 
TTGCCTGAGG CATTTCTCTA CATTGGATGG GCTCCTGCCC GCTATGTTGT GGCTGTTGGC 
TCCCTCTGTG CTCTTTCTAC CAGCCTCCTG GGCTCCATGT TCCCCATGCC TCGGGTGATC 
TACGCGATGG CAGAGGATGG CCTCCTGTTC CGTGTACTTG CTCGGATCCA CACCGGCACA 
CGCACCCCAA TCATAGCCAC CGTGGTCTCT GGCATTATTG CAGCATTCAT GGCATTCCTC 
TTCAAACTCA CTGATCTTGT GGACCTCATG TCAATTGGGA CCCTGCTTGC TTACTCCCTG 
GTGTCGATTT GTGTTCTCAT CCTCAGGTAT CAACCTGATC AGGAGACAAA GACTGGGGAA 
GAAGTGGAGT TGCAGGAGGA GGCAATAACT ACTGAATCAG AGAAGTTGAC CCTATGGGGA 
CTATTTTTCC CACTCAACTC CATCCCCACT CCACTCTCTG GCCAAATTGT CTATGTTTGT 
TCCTCATTGC TTGCTGTCCT GCTGACTGCT CTTTGCCTGG TGCTGGCCCA GTGGTCAGTT 
CCATTGCTTT CTGGAGACCT GCTGTGGACT GCAGTGGTTG TGCTGCTCCT GCTGCTCATT 
ATTGGGATCA TTGTGGTCAT CTGGAGACAG CCACAGAGTT CCACTCCCCT TCACTTTAAG 
GTGCCTGCTT TGCCTCTCCT CCCACTAATG AGCATCTTTG TGAATATTTA CCTTATGATG 
CAGATGACAG CTGGTACCTG GGCCCGATTT GGGGTCTGGA TGCTGATTGG CTTTGCTATC 
TACTTCGGCT ATGGGATCCA GCACAGCCTG GAAGAGATTA AGAGTAACCA ACCCTCACGC 
AAGTCTAGAG CCAAAACTGT AGACCTTGAT CCCGGCACTC TCTATGTCCA CTCAGTTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SLC7A3 ( NM_001048164.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001041629.1 Homo sapiens solute carrier family 7 member 3 (SLC7A3), transcript variant 2, mRNA.

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CloneID	OHu21460
Clone ID Related Accession (Same CDS sequence)	XM_017029912.1 , NM_001048164.3 , NM_032803.5 , NM_001048164.2 , NM_032803.6
Accession Version	NM_001048164.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1860bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-21
Organism	Homo sapiens(human)
Product	cationic amino acid transporter 3
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK075014.1 and BC033816.1. On May 26, 2010 this sequence version replaced NM_001048164.1. Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Both variants 1 and 2 encode the same protein. ##Evidence-Data-START## Transcript exon combination :: AK075014.1, SRR1803616.19483.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2155974, SAMEA2156099 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCCGTGGC AAGCATTTCG CAGATTTGGT CAAAAGCTGG TACGCAGACG TACACTGGAG 
TCAGGCATGG CTGAGACTCG CCTTGCCAGA TGCCTAAGCA CCCTGGATTT AGTGGCCCTG 
GGTGTGGGCA GCACATTGGG TGCAGGCGTG TATGTCCTAG CTGGCGAGGT GGCCAAAGAT 
AAAGCAGGGC CATCCATTGT GATCTGCTTT TTGGTGGCTG CCCTGTCTTC TGTGTTGGCT 
GGGCTGTGCT ATGCGGAGTT TGGTGCCCGG GTTCCCCGTT CTGGTTCGGC ATATCTCTAC 
AGCTATGTCA CTGTGGGTGA ACTCTGGGCC TTCACCACTG GCTGGAACCT CATCCTCTCC 
TATGTCATTG GTACAGCCAG TGTGGCCCGG GCCTGGAGCT CTGCTTTTGA CAACCTGATT 
GGGAACCACA TCTCTAAGAC TCTGCAGGGG TCCATTGCAC TGCACGTGCC CCATGTCCTT 
GCAGAATATC CAGATTTCTT TGCTTTGGGC CTCGTGTTGC TGCTCACTGG ATTGTTGGCT 
CTCGGGGCTA GTGAGTCGGC CCTGGTTACC AAAGTGTTCA CAGGCGTGAA CCTTTTGGTT 
CTTGGGTTCG TCATGATCTC TGGCTTCGTT AAGGGGGACG TGCACAACTG GAAGCTCACA 
GAAGAGGACT ACGAATTGGC CATGGCTGAA CTCAATGACA CCTATAGCTT GGGTCCTCTG 
GGCTCTGGAG GATTTGTGCC TTTCGGCTTC GAGGGAATTC TCCGTGGAGC AGCGACCTGT 
TTCTATGCAT TTGTTGGTTT CGACTGTATT GCTACCACTG GAGAAGAAGC CCAGAATCCC 
CAGCGTTCCA TCCCGATGGG CATTGTGATC TCACTGTCTG TCTGCTTTTT GGCGTATTTT 
GCTGTCTCTT CTGCACTCAC CCTGATGATG CCTTACTACC AGCTTCAGCC TGAGAGCCCT 
TTGCCTGAGG CATTTCTCTA CATTGGATGG GCTCCTGCCC GCTATGTTGT GGCTGTTGGC 
TCCCTCTGTG CTCTTTCTAC CAGCCTCCTG GGCTCCATGT TCCCCATGCC TCGGGTGATC 
TACGCGATGG CAGAGGATGG CCTCCTGTTC CGTGTACTTG CTCGGATCCA CACCGGCACA 
CGCACCCCAA TCATAGCCAC CGTGGTCTCT GGCATTATTG CAGCATTCAT GGCATTCCTC 
TTCAAACTCA CTGATCTTGT GGACCTCATG TCAATTGGGA CCCTGCTTGC TTACTCCCTG 
GTGTCGATTT GTGTTCTCAT CCTCAGGTAT CAACCTGATC AGGAGACAAA GACTGGGGAA 
GAAGTGGAGT TGCAGGAGGA GGCAATAACT ACTGAATCAG AGAAGTTGAC CCTATGGGGA 
CTATTTTTCC CACTCAACTC CATCCCCACT CCACTCTCTG GCCAAATTGT CTATGTTTGT 
TCCTCATTGC TTGCTGTCCT GCTGACTGCT CTTTGCCTGG TGCTGGCCCA GTGGTCAGTT 
CCATTGCTTT CTGGAGACCT GCTGTGGACT GCAGTGGTTG TGCTGCTCCT GCTGCTCATT 
ATTGGGATCA TTGTGGTCAT CTGGAGACAG CCACAGAGTT CCACTCCCCT TCACTTTAAG 
GTGCCTGCTT TGCCTCTCCT CCCACTAATG AGCATCTTTG TGAATATTTA CCTTATGATG 
CAGATGACAG CTGGTACCTG GGCCCGATTT GGGGTCTGGA TGCTGATTGG CTTTGCTATC 
TACTTCGGCT ATGGGATCCA GCACAGCCTG GAAGAGATTA AGAGTAACCA ACCCTCACGC 
AAGTCTAGAG CCAAAACTGT AGACCTTGAT CCCGGCACTC TCTATGTCCA CTCAGTTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001041629.1
CDS	151..2010
Translation	MPWQAFRRFGQKLVRRRTLESGMAETRLARCLSTLDLVALGVGSTLGAGVYVLAGEVAKDKAGPSIVICFLVAALSSVLAGLCYAEFGARVPRSGSAYLYSYVTVGELWAFTTGWNLILSYVIGTASVARAWSSAFDNLIGNHISKTLQGSIALHVPHVLAEYPDFFALGLVLLLTGLLALGASESALVTKVFTGVNLLVLGFVMISGFVKGDVHNWKLTEEDYELAMAELNDTYSLGPLGSGGFVPFGFEGILRGAATCFYAFVGFDCIATTGEEAQNPQRSIPMGIVISLSVCFLAYFAVSSALTLMMPYYQLQPESPLPEAFLYIGWAPARYVVAVGSLCALSTSLLGSMFPMPRVIYAMAEDGLLFRVLARIHTGTRTPIIATVVSGIIAAFMAFLFKLTDLVDLMSIGTLLAYSLVSICVLILRYQPDQETKTGEEVELQEEAITTESEKLTLWGLFFPLNSIPTPLSGQIVYVCSSLLAVLLTALCLVLAQWSVPLLSGDLLWTAVVVLLLLLIIGIIVVIWRQPQSSTPLHFKVPALPLLPLMSIFVNIYLMMQMTAGTWARFGVWMLIGFAIYFGYGIQHSLEEIKSNQPSRKSRAKTVDLDPGTLYVHSV

Target ORF information:

RefSeq Version	NM_001048164.2
Organism	Homo sapiens(human)
Definition	Homo sapiens solute carrier family 7 member 3 (SLC7A3), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001048164.2

ORF Insert Sequence:

ATGCCGTGGC AAGCATTTCG CAGATTTGGT CAAAAGCTGG TACGCAGACG TACACTGGAG 
TCAGGCATGG CTGAGACTCG CCTTGCCAGA TGCCTAAGCA CCCTGGATTT AGTGGCCCTG 
GGTGTGGGCA GCACATTGGG TGCAGGCGTG TATGTCCTAG CTGGCGAGGT GGCCAAAGAT 
AAAGCAGGGC CATCCATTGT GATCTGCTTT TTGGTGGCTG CCCTGTCTTC TGTGTTGGCT 
GGGCTGTGCT ATGCGGAGTT TGGTGCCCGG GTTCCCCGTT CTGGTTCGGC ATATCTCTAC 
AGCTATGTCA CTGTGGGTGA ACTCTGGGCC TTCACCACTG GCTGGAACCT CATCCTCTCC 
TATGTCATTG GTACAGCCAG TGTGGCCCGG GCCTGGAGCT CTGCTTTTGA CAACCTGATT 
GGGAACCACA TCTCTAAGAC TCTGCAGGGG TCCATTGCAC TGCACGTGCC CCATGTCCTT 
GCAGAATATC CAGATTTCTT TGCTTTGGGC CTCGTGTTGC TGCTCACTGG ATTGTTGGCT 
CTCGGGGCTA GTGAGTCGGC CCTGGTTACC AAAGTGTTCA CAGGCGTGAA CCTTTTGGTT 
CTTGGGTTCG TCATGATCTC TGGCTTCGTT AAGGGGGACG TGCACAACTG GAAGCTCACA 
GAAGAGGACT ACGAATTGGC CATGGCTGAA CTCAATGACA CCTATAGCTT GGGTCCTCTG 
GGCTCTGGAG GATTTGTGCC TTTCGGCTTC GAGGGAATTC TCCGTGGAGC AGCGACCTGT 
TTCTATGCAT TTGTTGGTTT CGACTGTATT GCTACCACTG GAGAAGAAGC CCAGAATCCC 
CAGCGTTCCA TCCCGATGGG CATTGTGATC TCACTGTCTG TCTGCTTTTT GGCGTATTTT 
GCTGTCTCTT CTGCACTCAC CCTGATGATG CCTTACTACC AGCTTCAGCC TGAGAGCCCT 
TTGCCTGAGG CATTTCTCTA CATTGGATGG GCTCCTGCCC GCTATGTTGT GGCTGTTGGC 
TCCCTCTGTG CTCTTTCTAC CAGCCTCCTG GGCTCCATGT TCCCCATGCC TCGGGTGATC 
TACGCGATGG CAGAGGATGG CCTCCTGTTC CGTGTACTTG CTCGGATCCA CACCGGCACA 
CGCACCCCAA TCATAGCCAC CGTGGTCTCT GGCATTATTG CAGCATTCAT GGCATTCCTC 
TTCAAACTCA CTGATCTTGT GGACCTCATG TCAATTGGGA CCCTGCTTGC TTACTCCCTG 
GTGTCGATTT GTGTTCTCAT CCTCAGGTAT CAACCTGATC AGGAGACAAA GACTGGGGAA 
GAAGTGGAGT TGCAGGAGGA GGCAATAACT ACTGAATCAG AGAAGTTGAC CCTATGGGGA 
CTATTTTTCC CACTCAACTC CATCCCCACT CCACTCTCTG GCCAAATTGT CTATGTTTGT 
TCCTCATTGC TTGCTGTCCT GCTGACTGCT CTTTGCCTGG TGCTGGCCCA GTGGTCAGTT 
CCATTGCTTT CTGGAGACCT GCTGTGGACT GCAGTGGTTG TGCTGCTCCT GCTGCTCATT 
ATTGGGATCA TTGTGGTCAT CTGGAGACAG CCACAGAGTT CCACTCCCCT TCACTTTAAG 
GTGCCTGCTT TGCCTCTCCT CCCACTAATG AGCATCTTTG TGAATATTTA CCTTATGATG 
CAGATGACAG CTGGTACCTG GGCCCGATTT GGGGTCTGGA TGCTGATTGG CTTTGCTATC 
TACTTCGGCT ATGGGATCCA GCACAGCCTG GAAGAGATTA AGAGTAACCA ACCCTCACGC 
AAGTCTAGAG CCAAAACTGT AGACCTTGAT CCCGGCACTC TCTATGTCCA CTCAGTTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SLC7A3 ( NM_032803.6 ) cDNA ORF clone, Homo sapiens(human) -> NP_116192.4 Homo sapiens solute carrier family 7 member 3 (SLC7A3), transcript variant 1, mRNA.

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CloneID	OHu21460
Clone ID Related Accession (Same CDS sequence)	XM_017029912.1 , NM_001048164.3 , NM_032803.5 , NM_001048164.2 , NM_032803.6
Accession Version	NM_032803.6 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1860bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-21
Organism	Homo sapiens(human)
Product	cationic amino acid transporter 3
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK074865.1, AL627071.16 and BC033816.1. This sequence is a reference standard in the RefSeqGene project. On Nov 23, 2018 this sequence version replaced NM_032803.5. Transcript Variant: This variant (1) represents the longer transcript. Both variants 1 and 2 encode the same protein. ##Evidence-Data-START## Transcript exon combination :: AK074865.1, AF320612.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968189, SAMEA2145743 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000374299.8/ ENSP00000363417.3 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGCCGTGGC AAGCATTTCG CAGATTTGGT CAAAAGCTGG TACGCAGACG TACACTGGAG 
TCAGGCATGG CTGAGACTCG CCTTGCCAGA TGCCTAAGCA CCCTGGATTT AGTGGCCCTG 
GGTGTGGGCA GCACATTGGG TGCAGGCGTG TATGTCCTAG CTGGCGAGGT GGCCAAAGAT 
AAAGCAGGGC CATCCATTGT GATCTGCTTT TTGGTGGCTG CCCTGTCTTC TGTGTTGGCT 
GGGCTGTGCT ATGCGGAGTT TGGTGCCCGG GTTCCCCGTT CTGGTTCGGC ATATCTCTAC 
AGCTATGTCA CTGTGGGTGA ACTCTGGGCC TTCACCACTG GCTGGAACCT CATCCTCTCC 
TATGTCATTG GTACAGCCAG TGTGGCCCGG GCCTGGAGCT CTGCTTTTGA CAACCTGATT 
GGGAACCACA TCTCTAAGAC TCTGCAGGGG TCCATTGCAC TGCACGTGCC CCATGTCCTT 
GCAGAATATC CAGATTTCTT TGCTTTGGGC CTCGTGTTGC TGCTCACTGG ATTGTTGGCT 
CTCGGGGCTA GTGAGTCGGC CCTGGTTACC AAAGTGTTCA CAGGCGTGAA CCTTTTGGTT 
CTTGGGTTCG TCATGATCTC TGGCTTCGTT AAGGGGGACG TGCACAACTG GAAGCTCACA 
GAAGAGGACT ACGAATTGGC CATGGCTGAA CTCAATGACA CCTATAGCTT GGGTCCTCTG 
GGCTCTGGAG GATTTGTGCC TTTCGGCTTC GAGGGAATTC TCCGTGGAGC AGCGACCTGT 
TTCTATGCAT TTGTTGGTTT CGACTGTATT GCTACCACTG GAGAAGAAGC CCAGAATCCC 
CAGCGTTCCA TCCCGATGGG CATTGTGATC TCACTGTCTG TCTGCTTTTT GGCGTATTTT 
GCTGTCTCTT CTGCACTCAC CCTGATGATG CCTTACTACC AGCTTCAGCC TGAGAGCCCT 
TTGCCTGAGG CATTTCTCTA CATTGGATGG GCTCCTGCCC GCTATGTTGT GGCTGTTGGC 
TCCCTCTGTG CTCTTTCTAC CAGCCTCCTG GGCTCCATGT TCCCCATGCC TCGGGTGATC 
TACGCGATGG CAGAGGATGG CCTCCTGTTC CGTGTACTTG CTCGGATCCA CACCGGCACA 
CGCACCCCAA TCATAGCCAC CGTGGTCTCT GGCATTATTG CAGCATTCAT GGCATTCCTC 
TTCAAACTCA CTGATCTTGT GGACCTCATG TCAATTGGGA CCCTGCTTGC TTACTCCCTG 
GTGTCGATTT GTGTTCTCAT CCTCAGGTAT CAACCTGATC AGGAGACAAA GACTGGGGAA 
GAAGTGGAGT TGCAGGAGGA GGCAATAACT ACTGAATCAG AGAAGTTGAC CCTATGGGGA 
CTATTTTTCC CACTCAACTC CATCCCCACT CCACTCTCTG GCCAAATTGT CTATGTTTGT 
TCCTCATTGC TTGCTGTCCT GCTGACTGCT CTTTGCCTGG TGCTGGCCCA GTGGTCAGTT 
CCATTGCTTT CTGGAGACCT GCTGTGGACT GCAGTGGTTG TGCTGCTCCT GCTGCTCATT 
ATTGGGATCA TTGTGGTCAT CTGGAGACAG CCACAGAGTT CCACTCCCCT TCACTTTAAG 
GTGCCTGCTT TGCCTCTCCT CCCACTAATG AGCATCTTTG TGAATATTTA CCTTATGATG 
CAGATGACAG CTGGTACCTG GGCCCGATTT GGGGTCTGGA TGCTGATTGG CTTTGCTATC 
TACTTCGGCT ATGGGATCCA GCACAGCCTG GAAGAGATTA AGAGTAACCA ACCCTCACGC 
AAGTCTAGAG CCAAAACTGT AGACCTTGAT CCCGGCACTC TCTATGTCCA CTCAGTTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_116192.4
CDS	146..2005
Translation	MPWQAFRRFGQKLVRRRTLESGMAETRLARCLSTLDLVALGVGSTLGAGVYVLAGEVAKDKAGPSIVICFLVAALSSVLAGLCYAEFGARVPRSGSAYLYSYVTVGELWAFTTGWNLILSYVIGTASVARAWSSAFDNLIGNHISKTLQGSIALHVPHVLAEYPDFFALGLVLLLTGLLALGASESALVTKVFTGVNLLVLGFVMISGFVKGDVHNWKLTEEDYELAMAELNDTYSLGPLGSGGFVPFGFEGILRGAATCFYAFVGFDCIATTGEEAQNPQRSIPMGIVISLSVCFLAYFAVSSALTLMMPYYQLQPESPLPEAFLYIGWAPARYVVAVGSLCALSTSLLGSMFPMPRVIYAMAEDGLLFRVLARIHTGTRTPIIATVVSGIIAAFMAFLFKLTDLVDLMSIGTLLAYSLVSICVLILRYQPDQETKTGEEVELQEEAITTESEKLTLWGLFFPLNSIPTPLSGQIVYVCSSLLAVLLTALCLVLAQWSVPLLSGDLLWTAVVVLLLLLIIGIIVVIWRQPQSSTPLHFKVPALPLLPLMSIFVNIYLMMQMTAGTWARFGVWMLIGFAIYFGYGIQHSLEEIKSNQPSRKSRAKTVDLDPGTLYVHSV

Target ORF information:

RefSeq Version	NM_032803.6
Organism	Homo sapiens(human)
Definition	Homo sapiens solute carrier family 7 member 3 (SLC7A3), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_032803.6

ORF Insert Sequence:

ATGCCGTGGC AAGCATTTCG CAGATTTGGT CAAAAGCTGG TACGCAGACG TACACTGGAG 
TCAGGCATGG CTGAGACTCG CCTTGCCAGA TGCCTAAGCA CCCTGGATTT AGTGGCCCTG 
GGTGTGGGCA GCACATTGGG TGCAGGCGTG TATGTCCTAG CTGGCGAGGT GGCCAAAGAT 
AAAGCAGGGC CATCCATTGT GATCTGCTTT TTGGTGGCTG CCCTGTCTTC TGTGTTGGCT 
GGGCTGTGCT ATGCGGAGTT TGGTGCCCGG GTTCCCCGTT CTGGTTCGGC ATATCTCTAC 
AGCTATGTCA CTGTGGGTGA ACTCTGGGCC TTCACCACTG GCTGGAACCT CATCCTCTCC 
TATGTCATTG GTACAGCCAG TGTGGCCCGG GCCTGGAGCT CTGCTTTTGA CAACCTGATT 
GGGAACCACA TCTCTAAGAC TCTGCAGGGG TCCATTGCAC TGCACGTGCC CCATGTCCTT 
GCAGAATATC CAGATTTCTT TGCTTTGGGC CTCGTGTTGC TGCTCACTGG ATTGTTGGCT 
CTCGGGGCTA GTGAGTCGGC CCTGGTTACC AAAGTGTTCA CAGGCGTGAA CCTTTTGGTT 
CTTGGGTTCG TCATGATCTC TGGCTTCGTT AAGGGGGACG TGCACAACTG GAAGCTCACA 
GAAGAGGACT ACGAATTGGC CATGGCTGAA CTCAATGACA CCTATAGCTT GGGTCCTCTG 
GGCTCTGGAG GATTTGTGCC TTTCGGCTTC GAGGGAATTC TCCGTGGAGC AGCGACCTGT 
TTCTATGCAT TTGTTGGTTT CGACTGTATT GCTACCACTG GAGAAGAAGC CCAGAATCCC 
CAGCGTTCCA TCCCGATGGG CATTGTGATC TCACTGTCTG TCTGCTTTTT GGCGTATTTT 
GCTGTCTCTT CTGCACTCAC CCTGATGATG CCTTACTACC AGCTTCAGCC TGAGAGCCCT 
TTGCCTGAGG CATTTCTCTA CATTGGATGG GCTCCTGCCC GCTATGTTGT GGCTGTTGGC 
TCCCTCTGTG CTCTTTCTAC CAGCCTCCTG GGCTCCATGT TCCCCATGCC TCGGGTGATC 
TACGCGATGG CAGAGGATGG CCTCCTGTTC CGTGTACTTG CTCGGATCCA CACCGGCACA 
CGCACCCCAA TCATAGCCAC CGTGGTCTCT GGCATTATTG CAGCATTCAT GGCATTCCTC 
TTCAAACTCA CTGATCTTGT GGACCTCATG TCAATTGGGA CCCTGCTTGC TTACTCCCTG 
GTGTCGATTT GTGTTCTCAT CCTCAGGTAT CAACCTGATC AGGAGACAAA GACTGGGGAA 
GAAGTGGAGT TGCAGGAGGA GGCAATAACT ACTGAATCAG AGAAGTTGAC CCTATGGGGA 
CTATTTTTCC CACTCAACTC CATCCCCACT CCACTCTCTG GCCAAATTGT CTATGTTTGT 
TCCTCATTGC TTGCTGTCCT GCTGACTGCT CTTTGCCTGG TGCTGGCCCA GTGGTCAGTT 
CCATTGCTTT CTGGAGACCT GCTGTGGACT GCAGTGGTTG TGCTGCTCCT GCTGCTCATT 
ATTGGGATCA TTGTGGTCAT CTGGAGACAG CCACAGAGTT CCACTCCCCT TCACTTTAAG 
GTGCCTGCTT TGCCTCTCCT CCCACTAATG AGCATCTTTG TGAATATTTA CCTTATGATG 
CAGATGACAG CTGGTACCTG GGCCCGATTT GGGGTCTGGA TGCTGATTGG CTTTGCTATC 
TACTTCGGCT ATGGGATCCA GCACAGCCTG GAAGAGATTA AGAGTAACCA ACCCTCACGC 
AAGTCTAGAG CCAAAACTGT AGACCTTGAT CCCGGCACTC TCTATGTCCA CTCAGTTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SLC7A3 ( XM_017029912.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016885401.1 Homo sapiens solute carrier family 7 member 3 (SLC7A3), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu21460
Clone ID Related Accession (Same CDS sequence)	XM_017029912.1 , NM_001048164.3 , NM_032803.5 , NM_001048164.2 , NM_032803.6
Accession Version	XM_017029912.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1860bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	cationic amino acid transporter 3 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000023.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCCGTGGC AAGCATTTCG CAGATTTGGT CAAAAGCTGG TACGCAGACG TACACTGGAG 
TCAGGCATGG CTGAGACTCG CCTTGCCAGA TGCCTAAGCA CCCTGGATTT AGTGGCCCTG 
GGTGTGGGCA GCACATTGGG TGCAGGCGTG TATGTCCTAG CTGGCGAGGT GGCCAAAGAT 
AAAGCAGGGC CATCCATTGT GATCTGCTTT TTGGTGGCTG CCCTGTCTTC TGTGTTGGCT 
GGGCTGTGCT ATGCGGAGTT TGGTGCCCGG GTTCCCCGTT CTGGTTCGGC ATATCTCTAC 
AGCTATGTCA CTGTGGGTGA ACTCTGGGCC TTCACCACTG GCTGGAACCT CATCCTCTCC 
TATGTCATTG GTACAGCCAG TGTGGCCCGG GCCTGGAGCT CTGCTTTTGA CAACCTGATT 
GGGAACCACA TCTCTAAGAC TCTGCAGGGG TCCATTGCAC TGCACGTGCC CCATGTCCTT 
GCAGAATATC CAGATTTCTT TGCTTTGGGC CTCGTGTTGC TGCTCACTGG ATTGTTGGCT 
CTCGGGGCTA GTGAGTCGGC CCTGGTTACC AAAGTGTTCA CAGGCGTGAA CCTTTTGGTT 
CTTGGGTTCG TCATGATCTC TGGCTTCGTT AAGGGGGACG TGCACAACTG GAAGCTCACA 
GAAGAGGACT ACGAATTGGC CATGGCTGAA CTCAATGACA CCTATAGCTT GGGTCCTCTG 
GGCTCTGGAG GATTTGTGCC TTTCGGCTTC GAGGGAATTC TCCGTGGAGC AGCGACCTGT 
TTCTATGCAT TTGTTGGTTT CGACTGTATT GCTACCACTG GAGAAGAAGC CCAGAATCCC 
CAGCGTTCCA TCCCGATGGG CATTGTGATC TCACTGTCTG TCTGCTTTTT GGCGTATTTT 
GCTGTCTCTT CTGCACTCAC CCTGATGATG CCTTACTACC AGCTTCAGCC TGAGAGCCCT 
TTGCCTGAGG CATTTCTCTA CATTGGATGG GCTCCTGCCC GCTATGTTGT GGCTGTTGGC 
TCCCTCTGTG CTCTTTCTAC CAGCCTCCTG GGCTCCATGT TCCCCATGCC TCGGGTGATC 
TACGCGATGG CAGAGGATGG CCTCCTGTTC CGTGTACTTG CTCGGATCCA CACCGGCACA 
CGCACCCCAA TCATAGCCAC CGTGGTCTCT GGCATTATTG CAGCATTCAT GGCATTCCTC 
TTCAAACTCA CTGATCTTGT GGACCTCATG TCAATTGGGA CCCTGCTTGC TTACTCCCTG 
GTGTCGATTT GTGTTCTCAT CCTCAGGTAT CAACCTGATC AGGAGACAAA GACTGGGGAA 
GAAGTGGAGT TGCAGGAGGA GGCAATAACT ACTGAATCAG AGAAGTTGAC CCTATGGGGA 
CTATTTTTCC CACTCAACTC CATCCCCACT CCACTCTCTG GCCAAATTGT CTATGTTTGT 
TCCTCATTGC TTGCTGTCCT GCTGACTGCT CTTTGCCTGG TGCTGGCCCA GTGGTCAGTT 
CCATTGCTTT CTGGAGACCT GCTGTGGACT GCAGTGGTTG TGCTGCTCCT GCTGCTCATT 
ATTGGGATCA TTGTGGTCAT CTGGAGACAG CCACAGAGTT CCACTCCCCT TCACTTTAAG 
GTGCCTGCTT TGCCTCTCCT CCCACTAATG AGCATCTTTG TGAATATTTA CCTTATGATG 
CAGATGACAG CTGGTACCTG GGCCCGATTT GGGGTCTGGA TGCTGATTGG CTTTGCTATC 
TACTTCGGCT ATGGGATCCA GCACAGCCTG GAAGAGATTA AGAGTAACCA ACCCTCACGC 
AAGTCTAGAG CCAAAACTGT AGACCTTGAT CCCGGCACTC TCTATGTCCA CTCAGTTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016885401.1
CDS	666..2525
Translation	MPWQAFRRFGQKLVRRRTLESGMAETRLARCLSTLDLVALGVGSTLGAGVYVLAGEVAKDKAGPSIVICFLVAALSSVLAGLCYAEFGARVPRSGSAYLYSYVTVGELWAFTTGWNLILSYVIGTASVARAWSSAFDNLIGNHISKTLQGSIALHVPHVLAEYPDFFALGLVLLLTGLLALGASESALVTKVFTGVNLLVLGFVMISGFVKGDVHNWKLTEEDYELAMAELNDTYSLGPLGSGGFVPFGFEGILRGAATCFYAFVGFDCIATTGEEAQNPQRSIPMGIVISLSVCFLAYFAVSSALTLMMPYYQLQPESPLPEAFLYIGWAPARYVVAVGSLCALSTSLLGSMFPMPRVIYAMAEDGLLFRVLARIHTGTRTPIIATVVSGIIAAFMAFLFKLTDLVDLMSIGTLLAYSLVSICVLILRYQPDQETKTGEEVELQEEAITTESEKLTLWGLFFPLNSIPTPLSGQIVYVCSSLLAVLLTALCLVLAQWSVPLLSGDLLWTAVVVLLLLLIIGIIVVIWRQPQSSTPLHFKVPALPLLPLMSIFVNIYLMMQMTAGTWARFGVWMLIGFAIYFGYGIQHSLEEIKSNQPSRKSRAKTVDLDPGTLYVHSV

Target ORF information:

RefSeq Version	XM_017029912.1
Organism	Homo sapiens(human)
Definition	Homo sapiens solute carrier family 7 member 3 (SLC7A3), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017029912.1

ORF Insert Sequence:

ATGCCGTGGC AAGCATTTCG CAGATTTGGT CAAAAGCTGG TACGCAGACG TACACTGGAG 
TCAGGCATGG CTGAGACTCG CCTTGCCAGA TGCCTAAGCA CCCTGGATTT AGTGGCCCTG 
GGTGTGGGCA GCACATTGGG TGCAGGCGTG TATGTCCTAG CTGGCGAGGT GGCCAAAGAT 
AAAGCAGGGC CATCCATTGT GATCTGCTTT TTGGTGGCTG CCCTGTCTTC TGTGTTGGCT 
GGGCTGTGCT ATGCGGAGTT TGGTGCCCGG GTTCCCCGTT CTGGTTCGGC ATATCTCTAC 
AGCTATGTCA CTGTGGGTGA ACTCTGGGCC TTCACCACTG GCTGGAACCT CATCCTCTCC 
TATGTCATTG GTACAGCCAG TGTGGCCCGG GCCTGGAGCT CTGCTTTTGA CAACCTGATT 
GGGAACCACA TCTCTAAGAC TCTGCAGGGG TCCATTGCAC TGCACGTGCC CCATGTCCTT 
GCAGAATATC CAGATTTCTT TGCTTTGGGC CTCGTGTTGC TGCTCACTGG ATTGTTGGCT 
CTCGGGGCTA GTGAGTCGGC CCTGGTTACC AAAGTGTTCA CAGGCGTGAA CCTTTTGGTT 
CTTGGGTTCG TCATGATCTC TGGCTTCGTT AAGGGGGACG TGCACAACTG GAAGCTCACA 
GAAGAGGACT ACGAATTGGC CATGGCTGAA CTCAATGACA CCTATAGCTT GGGTCCTCTG 
GGCTCTGGAG GATTTGTGCC TTTCGGCTTC GAGGGAATTC TCCGTGGAGC AGCGACCTGT 
TTCTATGCAT TTGTTGGTTT CGACTGTATT GCTACCACTG GAGAAGAAGC CCAGAATCCC 
CAGCGTTCCA TCCCGATGGG CATTGTGATC TCACTGTCTG TCTGCTTTTT GGCGTATTTT 
GCTGTCTCTT CTGCACTCAC CCTGATGATG CCTTACTACC AGCTTCAGCC TGAGAGCCCT 
TTGCCTGAGG CATTTCTCTA CATTGGATGG GCTCCTGCCC GCTATGTTGT GGCTGTTGGC 
TCCCTCTGTG CTCTTTCTAC CAGCCTCCTG GGCTCCATGT TCCCCATGCC TCGGGTGATC 
TACGCGATGG CAGAGGATGG CCTCCTGTTC CGTGTACTTG CTCGGATCCA CACCGGCACA 
CGCACCCCAA TCATAGCCAC CGTGGTCTCT GGCATTATTG CAGCATTCAT GGCATTCCTC 
TTCAAACTCA CTGATCTTGT GGACCTCATG TCAATTGGGA CCCTGCTTGC TTACTCCCTG 
GTGTCGATTT GTGTTCTCAT CCTCAGGTAT CAACCTGATC AGGAGACAAA GACTGGGGAA 
GAAGTGGAGT TGCAGGAGGA GGCAATAACT ACTGAATCAG AGAAGTTGAC CCTATGGGGA 
CTATTTTTCC CACTCAACTC CATCCCCACT CCACTCTCTG GCCAAATTGT CTATGTTTGT 
TCCTCATTGC TTGCTGTCCT GCTGACTGCT CTTTGCCTGG TGCTGGCCCA GTGGTCAGTT 
CCATTGCTTT CTGGAGACCT GCTGTGGACT GCAGTGGTTG TGCTGCTCCT GCTGCTCATT 
ATTGGGATCA TTGTGGTCAT CTGGAGACAG CCACAGAGTT CCACTCCCCT TCACTTTAAG 
GTGCCTGCTT TGCCTCTCCT CCCACTAATG AGCATCTTTG TGAATATTTA CCTTATGATG 
CAGATGACAG CTGGTACCTG GGCCCGATTT GGGGTCTGGA TGCTGATTGG CTTTGCTATC 
TACTTCGGCT ATGGGATCCA GCACAGCCTG GAAGAGATTA AGAGTAACCA ACCCTCACGC 
AAGTCTAGAG CCAAAACTGT AGACCTTGAT CCCGGCACTC TCTATGTCCA CTCAGTTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Hypomorphic variants of cationic amino acid transporter 3 in males with autism spectrum disorders.
Amino acids47(12)2647-58(2015 Dec)
Nava C,Rupp J,Boissel JP,Mignot C,Rastetter A,Amiet C,Jacquette A,Dupuits C,Bouteiller D,Keren B,Ruberg M,Faudet A,Doummar D,Philippe A,P?risse D,Laurent C,Lebrun N,Guillemot V,Chelly J,Cohen D,H?ron D,Brice A,Closs EI,Depienne C

Genetic ablation of solute carrier family 7a3a leads to hepatic steatosis in zebrafish during fasting.
Hepatology (Baltimore, Md.)60(6)1929-41(2014 Dec)
Gu Q,Yang X,Lin L,Li S,Li Q,Zhong S,Peng J,Cui Z

Differential topochemistry of three cationic amino acid transporter proteins, hCAT1, hCAT2 and hCAT3, in the adult human brain.
Amino acids44(2)423-33(2013 Feb)
J?ger K,Wolf S,Dobrowolny H,Steiner J,Nave H,Maronde E,Bogerts B,Bernstein HG

Activation of classical protein kinase C reduces the expression of human cationic amino acid transporter 3 (hCAT-3) in the plasma membrane.
The Biochemical journal395(1)117-23(2006 Apr)
Rotmann A,V?kony N,Gassner D,Niegisch G,Strand D,Martin? U,Closs EI

Monovalent cation conductance in Xenopus laevis oocytes expressing hCAT-3.
Biochimica et biophysica acta1668(2)234-9(2005 Mar)
Gilles W,Vulcu SD,Liewald JF,Habermeier A,V?kony N,Closs EI,Rupp J,Nawrath H

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SLC7A3 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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