SPPL2A cDNA ORF clone, Homo sapiens(human)

The following SPPL2A gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the SPPL2A cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID Accession No. Definition **Vector *Turnaround time Price (USD) Select
OHu25893 NM_032802.4
Latest version!
Homo sapiens signal peptide peptidase like 2A (SPPL2A), mRNA. pcDNA3.1-C-(k)DYK or customized vector 5-7 $265.30
$379.00
OHu48618 XM_005254722.3
Latest version!
Homo sapiens signal peptide peptidase like 2A (SPPL2A), transcript variant X1, mRNA. pcDNA3.1-C-(k)DYK or customized vector 7-9 $307.30
$439.00
OHu85712 XM_017022680.1
Latest version!
Homo sapiens signal peptide peptidase like 2A (SPPL2A), transcript variant X2, mRNA. pcDNA3.1-C-(k)DYK or customized vector 9-11 $223.30
$319.00
OHu85713 XM_017022681.1
Latest version!
Homo sapiens signal peptide peptidase like 2A (SPPL2A), transcript variant X3, mRNA. pcDNA3.1-C-(k)DYK or customized vector 9-11 $223.30
$319.00
View Old Accession Versions >>
OHu25893 NM_032802.3 Homo sapiens signal peptide peptidase like 2A (SPPL2A), mRNA. pcDNA3.1-C-(k)DYK or customized vector 5-7 $265.30
$379.00
Hide Old Accession Versions >>

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

  • Reference Sequences (Refseq)
    CloneID OHu25893
    Clone ID Related Accession (Same CDS sequence) NM_032802.3 , NM_032802.4
    Accession Version NM_032802.3 Documents for ORF clone product in default vector
    Sequence Information ORF Nucleotide Sequence (Length: 1563bp)
    Protein sequence
    SNP
    Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
    Clone information Clone Map MSDS
    Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
    ORF Insert Method CloneEZ™ Seamless cloning technology
    Insert Structure linear
    Update Date 2017-10-01
    Organism Homo sapiens(human)
    Product signal peptide peptidase-like 2A precursor
    Comment Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA023801.1, AY169314.1, AK027446.1 and AA988423.1. On Aug 16, 2006 this sequence version replaced NM_032802.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660803.160277.1, SRR1803617.257716.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    ATGGGGCCGC AGCGGCGGCT GTCCCCTGCC GGGGCCGCCC TACTCTGGGG CTTCCTGCTC 
    CAGCTGACAG CCGCTCAGGA AGCAATCTTG CATGCGTCTG GAAATGGCAC AACCAAGGAC
    TACTGCATGC TTTATAACCC TTATTGGACA GCTCTTCCAA GTACCCTAGA AAATGCAACT
    TCCATTAGTT TGATGAATCT GACTTCCACA CCACTATGCA ACCTTTCTGA TATTCCTCCT
    GTTGGCATAA AGAGCAAAGC AGTTGTGGTT CCATGGGGAA GCTGCCATTT TCTTGAAAAA
    GCCAGAATTG CACAGAAAGG AGGTGCTGAA GCAATGTTAG TTGTCAATAA CAGTGTCCTA
    TTTCCTCCCT CAGGTAACAG ATCTGAATTT CCTGATGTGA AAATACTGAT TGCATTTATA
    AGCTACAAAG ACTTTAGAGA TATGAACCAG ACTCTAGGAG ATAACATTAC TGTGAAAATG
    TATTCTCCAT CGTGGCCTAA CTTTGATTAT ACTATGGTGG TTATTTTTGT AATTGCGGTG
    TTCACTGTGG CATTAGGTGG ATACTGGAGT GGACTAGTTG AATTGGAAAA CTTGAAAGCA
    GTGACAACTG AAGATAGAGA AATGAGGAAA AAGAAGGAAG AATATTTAAC TTTTAGTCCT
    CTTACAGTTG TAATATTTGT GGTCATCTGC TGTGTTATGA TGGTCTTACT TTATTTCTTC
    TACAAATGGT TGGTTTATGT TATGATAGCA ATTTTCTGCA TAGCATCAGC AATGAGTCTG
    TACAACTGTC TTGCTGCACT AATTCATAAG ATACCATATG GACAATGCAC GATTGCATGT
    CGTGGCAAAA ACATGGAAGT GAGACTTATT TTTCTCTCTG GACTGTGCAT AGCAGTAGCT
    GTTGTTTGGG CTGTGTTTCG AAATGAAGAC AGGTGGGCTT GGATTTTACA GGATATCTTG
    GGGATTGCTT TCTGTCTGAA TTTAATTAAA ACACTGAAGT TGCCCAACTT CAAGTCATGT
    GTGATACTTC TAGGCCTTCT CCTCCTCTAT GATGTATTTT TTGTTTTCAT AACACCATTC
    ATCACAAAGA ATGGTGAGAG TATCATGGTT GAACTCGCAG CTGGACCTTT TGGAAATAAT
    GAAAAGTTGC CAGTAGTCAT CAGAGTACCA AAACTGATCT ATTTCTCAGT AATGAGTGTG
    TGCCTCATGC CTGTTTCAAT ATTGGGTTTT GGAGACATTA TTGTACCAGG CCTGTTGATT
    GCATACTGTA GAAGATTTGA TGTTCAGACT GGTTCTTCTT ACATATACTA TGTTTCGTCT
    ACAGTTGCCT ATGCTATTGG CATGATACTT ACATTTGTTG TTCTGGTGCT GATGAAAAAG
    GGGCAACCTG CTCTCCTCTA TTTAGTACCT TGCACACTTA TTACTGCCTC AGTTGTTGCC
    TGGAGACGTA AGGAAATGAA AAAGTTCTGG AAAGGTAACA GCTATCAGAT GATGGACCAT
    TTGGATTGTG CAACAAATGA AGAAAACCCT GTGATATCTG GTGAACAGAT TGTCCAGCAA
    TAA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    RefSeq NP_116191.2
    CDS181..1743
    Translation

    Target ORF information:

    RefSeq Version NM_032802.3
    Organism Homo sapiens(human)
    Definition Homo sapiens signal peptide peptidase like 2A (SPPL2A), mRNA.

    Target ORF information:

    Epitope DYKDDDDK
    Bacterial selection AMPR
    Mammalian selection NeoR
    Vector pcDNA3.1+/C-(K)DYK
    NM_032802.3

    ORF Insert Sequence:

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    ATGGGGCCGC AGCGGCGGCT GTCCCCTGCC GGGGCCGCCC TACTCTGGGG CTTCCTGCTC 
    CAGCTGACAG CCGCTCAGGA AGCAATCTTG CATGCGTCTG GAAATGGCAC AACCAAGGAC
    TACTGCATGC TTTATAACCC TTATTGGACA GCTCTTCCAA GTACCCTAGA AAATGCAACT
    TCCATTAGTT TGATGAATCT GACTTCCACA CCACTATGCA ACCTTTCTGA TATTCCTCCT
    GTTGGCATAA AGAGCAAAGC AGTTGTGGTT CCATGGGGAA GCTGCCATTT TCTTGAAAAA
    GCCAGAATTG CACAGAAAGG AGGTGCTGAA GCAATGTTAG TTGTCAATAA CAGTGTCCTA
    TTTCCTCCCT CAGGTAACAG ATCTGAATTT CCTGATGTGA AAATACTGAT TGCATTTATA
    AGCTACAAAG ACTTTAGAGA TATGAACCAG ACTCTAGGAG ATAACATTAC TGTGAAAATG
    TATTCTCCAT CGTGGCCTAA CTTTGATTAT ACTATGGTGG TTATTTTTGT AATTGCGGTG
    TTCACTGTGG CATTAGGTGG ATACTGGAGT GGACTAGTTG AATTGGAAAA CTTGAAAGCA
    GTGACAACTG AAGATAGAGA AATGAGGAAA AAGAAGGAAG AATATTTAAC TTTTAGTCCT
    CTTACAGTTG TAATATTTGT GGTCATCTGC TGTGTTATGA TGGTCTTACT TTATTTCTTC
    TACAAATGGT TGGTTTATGT TATGATAGCA ATTTTCTGCA TAGCATCAGC AATGAGTCTG
    TACAACTGTC TTGCTGCACT AATTCATAAG ATACCATATG GACAATGCAC GATTGCATGT
    CGTGGCAAAA ACATGGAAGT GAGACTTATT TTTCTCTCTG GACTGTGCAT AGCAGTAGCT
    GTTGTTTGGG CTGTGTTTCG AAATGAAGAC AGGTGGGCTT GGATTTTACA GGATATCTTG
    GGGATTGCTT TCTGTCTGAA TTTAATTAAA ACACTGAAGT TGCCCAACTT CAAGTCATGT
    GTGATACTTC TAGGCCTTCT CCTCCTCTAT GATGTATTTT TTGTTTTCAT AACACCATTC
    ATCACAAAGA ATGGTGAGAG TATCATGGTT GAACTCGCAG CTGGACCTTT TGGAAATAAT
    GAAAAGTTGC CAGTAGTCAT CAGAGTACCA AAACTGATCT ATTTCTCAGT AATGAGTGTG
    TGCCTCATGC CTGTTTCAAT ATTGGGTTTT GGAGACATTA TTGTACCAGG CCTGTTGATT
    GCATACTGTA GAAGATTTGA TGTTCAGACT GGTTCTTCTT ACATATACTA TGTTTCGTCT
    ACAGTTGCCT ATGCTATTGG CATGATACTT ACATTTGTTG TTCTGGTGCT GATGAAAAAG
    GGGCAACCTG CTCTCCTCTA TTTAGTACCT TGCACACTTA TTACTGCCTC AGTTGTTGCC
    TGGAGACGTA AGGAAATGAA AAAGTTCTGG AAAGGTAACA GCTATCAGAT GATGGACCAT
    TTGGATTGTG CAACAAATGA AGAAAACCCT GTGATATCTG GTGAACAGAT TGTCCAGCAA
    TAA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    CloneID OHu25893
    Clone ID Related Accession (Same CDS sequence) NM_032802.3 , NM_032802.4
    Accession Version NM_032802.4 Latest version! Documents for ORF clone product in default vector
    Sequence Information ORF Nucleotide Sequence (Length: 1563bp)
    Protein sequence
    SNP
    Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
    Clone information Clone Map MSDS
    Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
    ORF Insert Method CloneEZ™ Seamless cloning technology
    Insert Structure linear
    Update Date 2019-09-26
    Organism Homo sapiens(human)
    Product signal peptide peptidase-like 2A precursor
    Comment Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AY169314.1, AK027446.1, AA988423.1 and AC012100.7. On Nov 22, 2018 this sequence version replaced NM_032802.3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803612.119776.1, SRR1660803.160277.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000261854.10/ ENSP00000261854.5 RefSeq Select criteria :: based on conservation, expression ##RefSeq-Attributes-END## COMPLETENESS: full length.

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    ATGGGGCCGC AGCGGCGGCT GTCCCCTGCC GGGGCCGCCC TACTCTGGGG CTTCCTGCTC 
    CAGCTGACAG CCGCTCAGGA AGCAATCTTG CATGCGTCTG GAAATGGCAC AACCAAGGAC
    TACTGCATGC TTTATAACCC TTATTGGACA GCTCTTCCAA GTACCCTAGA AAATGCAACT
    TCCATTAGTT TGATGAATCT GACTTCCACA CCACTATGCA ACCTTTCTGA TATTCCTCCT
    GTTGGCATAA AGAGCAAAGC AGTTGTGGTT CCATGGGGAA GCTGCCATTT TCTTGAAAAA
    GCCAGAATTG CACAGAAAGG AGGTGCTGAA GCAATGTTAG TTGTCAATAA CAGTGTCCTA
    TTTCCTCCCT CAGGTAACAG ATCTGAATTT CCTGATGTGA AAATACTGAT TGCATTTATA
    AGCTACAAAG ACTTTAGAGA TATGAACCAG ACTCTAGGAG ATAACATTAC TGTGAAAATG
    TATTCTCCAT CGTGGCCTAA CTTTGATTAT ACTATGGTGG TTATTTTTGT AATTGCGGTG
    TTCACTGTGG CATTAGGTGG ATACTGGAGT GGACTAGTTG AATTGGAAAA CTTGAAAGCA
    GTGACAACTG AAGATAGAGA AATGAGGAAA AAGAAGGAAG AATATTTAAC TTTTAGTCCT
    CTTACAGTTG TAATATTTGT GGTCATCTGC TGTGTTATGA TGGTCTTACT TTATTTCTTC
    TACAAATGGT TGGTTTATGT TATGATAGCA ATTTTCTGCA TAGCATCAGC AATGAGTCTG
    TACAACTGTC TTGCTGCACT AATTCATAAG ATACCATATG GACAATGCAC GATTGCATGT
    CGTGGCAAAA ACATGGAAGT GAGACTTATT TTTCTCTCTG GACTGTGCAT AGCAGTAGCT
    GTTGTTTGGG CTGTGTTTCG AAATGAAGAC AGGTGGGCTT GGATTTTACA GGATATCTTG
    GGGATTGCTT TCTGTCTGAA TTTAATTAAA ACACTGAAGT TGCCCAACTT CAAGTCATGT
    GTGATACTTC TAGGCCTTCT CCTCCTCTAT GATGTATTTT TTGTTTTCAT AACACCATTC
    ATCACAAAGA ATGGTGAGAG TATCATGGTT GAACTCGCAG CTGGACCTTT TGGAAATAAT
    GAAAAGTTGC CAGTAGTCAT CAGAGTACCA AAACTGATCT ATTTCTCAGT AATGAGTGTG
    TGCCTCATGC CTGTTTCAAT ATTGGGTTTT GGAGACATTA TTGTACCAGG CCTGTTGATT
    GCATACTGTA GAAGATTTGA TGTTCAGACT GGTTCTTCTT ACATATACTA TGTTTCGTCT
    ACAGTTGCCT ATGCTATTGG CATGATACTT ACATTTGTTG TTCTGGTGCT GATGAAAAAG
    GGGCAACCTG CTCTCCTCTA TTTAGTACCT TGCACACTTA TTACTGCCTC AGTTGTTGCC
    TGGAGACGTA AGGAAATGAA AAAGTTCTGG AAAGGTAACA GCTATCAGAT GATGGACCAT
    TTGGATTGTG CAACAAATGA AGAAAACCCT GTGATATCTG GTGAACAGAT TGTCCAGCAA
    TAA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    RefSeq NP_116191.2
    CDS174..1736
    Translation

    Target ORF information:

    RefSeq Version NM_032802.4
    Organism Homo sapiens(human)
    Definition Homo sapiens signal peptide peptidase like 2A (SPPL2A), mRNA.

    Target ORF information:

    Epitope DYKDDDDK
    Bacterial selection AMPR
    Mammalian selection NeoR
    Vector pcDNA3.1+/C-(K)DYK
    NM_032802.4

    ORF Insert Sequence:

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    ATGGGGCCGC AGCGGCGGCT GTCCCCTGCC GGGGCCGCCC TACTCTGGGG CTTCCTGCTC 
    CAGCTGACAG CCGCTCAGGA AGCAATCTTG CATGCGTCTG GAAATGGCAC AACCAAGGAC
    TACTGCATGC TTTATAACCC TTATTGGACA GCTCTTCCAA GTACCCTAGA AAATGCAACT
    TCCATTAGTT TGATGAATCT GACTTCCACA CCACTATGCA ACCTTTCTGA TATTCCTCCT
    GTTGGCATAA AGAGCAAAGC AGTTGTGGTT CCATGGGGAA GCTGCCATTT TCTTGAAAAA
    GCCAGAATTG CACAGAAAGG AGGTGCTGAA GCAATGTTAG TTGTCAATAA CAGTGTCCTA
    TTTCCTCCCT CAGGTAACAG ATCTGAATTT CCTGATGTGA AAATACTGAT TGCATTTATA
    AGCTACAAAG ACTTTAGAGA TATGAACCAG ACTCTAGGAG ATAACATTAC TGTGAAAATG
    TATTCTCCAT CGTGGCCTAA CTTTGATTAT ACTATGGTGG TTATTTTTGT AATTGCGGTG
    TTCACTGTGG CATTAGGTGG ATACTGGAGT GGACTAGTTG AATTGGAAAA CTTGAAAGCA
    GTGACAACTG AAGATAGAGA AATGAGGAAA AAGAAGGAAG AATATTTAAC TTTTAGTCCT
    CTTACAGTTG TAATATTTGT GGTCATCTGC TGTGTTATGA TGGTCTTACT TTATTTCTTC
    TACAAATGGT TGGTTTATGT TATGATAGCA ATTTTCTGCA TAGCATCAGC AATGAGTCTG
    TACAACTGTC TTGCTGCACT AATTCATAAG ATACCATATG GACAATGCAC GATTGCATGT
    CGTGGCAAAA ACATGGAAGT GAGACTTATT TTTCTCTCTG GACTGTGCAT AGCAGTAGCT
    GTTGTTTGGG CTGTGTTTCG AAATGAAGAC AGGTGGGCTT GGATTTTACA GGATATCTTG
    GGGATTGCTT TCTGTCTGAA TTTAATTAAA ACACTGAAGT TGCCCAACTT CAAGTCATGT
    GTGATACTTC TAGGCCTTCT CCTCCTCTAT GATGTATTTT TTGTTTTCAT AACACCATTC
    ATCACAAAGA ATGGTGAGAG TATCATGGTT GAACTCGCAG CTGGACCTTT TGGAAATAAT
    GAAAAGTTGC CAGTAGTCAT CAGAGTACCA AAACTGATCT ATTTCTCAGT AATGAGTGTG
    TGCCTCATGC CTGTTTCAAT ATTGGGTTTT GGAGACATTA TTGTACCAGG CCTGTTGATT
    GCATACTGTA GAAGATTTGA TGTTCAGACT GGTTCTTCTT ACATATACTA TGTTTCGTCT
    ACAGTTGCCT ATGCTATTGG CATGATACTT ACATTTGTTG TTCTGGTGCT GATGAAAAAG
    GGGCAACCTG CTCTCCTCTA TTTAGTACCT TGCACACTTA TTACTGCCTC AGTTGTTGCC
    TGGAGACGTA AGGAAATGAA AAAGTTCTGG AAAGGTAACA GCTATCAGAT GATGGACCAT
    TTGGATTGTG CAACAAATGA AGAAAACCCT GTGATATCTG GTGAACAGAT TGTCCAGCAA
    TAA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    CloneID OHu48618
    Clone ID Related Accession (Same CDS sequence) XM_005254722.3
    Accession Version XM_005254722.3 Latest version! Documents for ORF clone product in default vector
    Sequence Information ORF Nucleotide Sequence (Length: 1617bp)
    Protein sequence
    SNP
    Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
    Clone information Clone Map MSDS
    Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
    ORF Insert Method CloneEZ™ Seamless cloning technology
    Insert Structure linear
    Update Date 2019-12-05
    Organism Homo sapiens(human)
    Product signal peptide peptidase-like 2A isoform X1
    Comment Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000015.10) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_005254722.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    ATGGGGCCGC AGCGGCGGCT GTCCCCTGCC GGGGCCGCCC TACTCTGGGG CTTCCTGCTC 
    CAGCTGACAG CCGCTCAGGA AGCAATCTTG CATGCGTCTG GAAATGGCAC AACCAAGGAC
    TACTGCATGC TTTATAACCC TTATTGGACA GCTCTTCCAA GTACCCTAGA AAATGCAACT
    TCCATTAGTT TGATGAATCT GACTTCCACA CCACTATGCA ACCTTTCTGA TATTCCTCCT
    GTTGGCATAA AGAGCAAAGC AGTTGTGGTT CCATGGGGAA GCTGCCATTT TCTTGAAAAA
    GCCAGAATTG CACAGAAAGG AGGTGCTGAA GCAATGTTAG TTGTCAATAA CAGTGTCCTA
    TTTCCTCCCT CAGGTAACAG ATCTGAATTT CCTGATGTGA AAATACTGAT TGCATTTATA
    AGCTACAAAG ACTTTAGAGA TATGAACCAG ACTCTAGGAG ATAACATTAC TGTGAAAATG
    TATTCTCCAT CGTGGCCTAA CTTTGATTAT ACTATGGTGG TTATTTTTGT AATTGCGGTG
    TTCACTGTGG CATTAGGTGG ATACTGGAGT GGACTAGTTG AATTGGAAAA CTTGAAAGCA
    GTGACAACTG AAGATAGAGA AATGAGGAAA AAGAAGGAAG AATATTTAAC TTTTAGTCCT
    CTTACAGTTG TAATATTTGT GGTCATCTGC TGTGTTATGA TGGTCTTACT TTATTTCTTC
    TACAAATGGT TGGTTTATGT TATGATAGCA ATTTTCTGCA TAGCATCAGC AATGAGTCTG
    TACAACTGTC TTGCTGCACT AATTCATAAG ATACCATATG GACAATGCAC GATTGCATGT
    CGTGGCAAAA ACATGGAAGT GAGACTTATT TTTCTCTCTG GACTGTGCAT AGCAGTAGCT
    GTTGTTTGGG CTGTGTTTCG AAATGAAGAC AGGTGGGCTT GGATTTTACA GGATATCTTG
    GGGATTGCTT TCTGTCTGAA TTTAATTAAA ACACTGAAGT TGCCCAACTT CAAGTCATGT
    GTGATACTTC TAGGCCTTCT CCTCCTCTAT GATGTATTTT TTGTTTTCAT AACACCATTC
    ATCACAAAGA ATGGTGAGAG TATCATGGTT GAACTCGCAG CTGGACCTTT TGGAAATAAT
    GAAAAGAATG ATGGAAACTT GGTGGAAGCC ACTGGTCAAC CCTCAGCTCC CCATGAGAAA
    TTGCCAGTAG TCATCAGAGT ACCAAAACTG ATCTATTTCT CAGTAATGAG TGTGTGCCTC
    ATGCCTGTTT CAATATTGGG TTTTGGAGAC ATTATTGTAC CAGGCCTGTT GATTGCATAC
    TGTAGAAGAT TTGATGTTCA GACTGGTTCT TCTTACATAT ACTATGTTTC GTCTACAGTT
    GCCTATGCTA TTGGCATGAT ACTTACATTT GTTGTTCTGG TGCTGATGAA AAAGGGGCAA
    CCTGCTCTCC TCTATTTAGT ACCTTGCACA CTTATTACTG CCTCAGTTGT TGCCTGGAGA
    CGTAAGGAAA TGAAAAAGTT CTGGAAAGGT AACAGCTATC AGATGATGGA CCATTTGGAT
    TGTGCAACAA ATGAAGAAAA CCCTGTGATA TCTGGTGAAC AGATTGTCCA GCAATAA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    RefSeq XP_005254779.1
    CDS180..1796
    Translation

    Target ORF information:

    RefSeq Version XM_005254722.3
    Organism Homo sapiens(human)
    Definition Homo sapiens signal peptide peptidase like 2A (SPPL2A), transcript variant X1, mRNA.

    Target ORF information:

    Epitope DYKDDDDK
    Bacterial selection AMPR
    Mammalian selection NeoR
    Vector pcDNA3.1+/C-(K)DYK
    XM_005254722.3

    ORF Insert Sequence:

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    ATGGGGCCGC AGCGGCGGCT GTCCCCTGCC GGGGCCGCCC TACTCTGGGG CTTCCTGCTC 
    CAGCTGACAG CCGCTCAGGA AGCAATCTTG CATGCGTCTG GAAATGGCAC AACCAAGGAC
    TACTGCATGC TTTATAACCC TTATTGGACA GCTCTTCCAA GTACCCTAGA AAATGCAACT
    TCCATTAGTT TGATGAATCT GACTTCCACA CCACTATGCA ACCTTTCTGA TATTCCTCCT
    GTTGGCATAA AGAGCAAAGC AGTTGTGGTT CCATGGGGAA GCTGCCATTT TCTTGAAAAA
    GCCAGAATTG CACAGAAAGG AGGTGCTGAA GCAATGTTAG TTGTCAATAA CAGTGTCCTA
    TTTCCTCCCT CAGGTAACAG ATCTGAATTT CCTGATGTGA AAATACTGAT TGCATTTATA
    AGCTACAAAG ACTTTAGAGA TATGAACCAG ACTCTAGGAG ATAACATTAC TGTGAAAATG
    TATTCTCCAT CGTGGCCTAA CTTTGATTAT ACTATGGTGG TTATTTTTGT AATTGCGGTG
    TTCACTGTGG CATTAGGTGG ATACTGGAGT GGACTAGTTG AATTGGAAAA CTTGAAAGCA
    GTGACAACTG AAGATAGAGA AATGAGGAAA AAGAAGGAAG AATATTTAAC TTTTAGTCCT
    CTTACAGTTG TAATATTTGT GGTCATCTGC TGTGTTATGA TGGTCTTACT TTATTTCTTC
    TACAAATGGT TGGTTTATGT TATGATAGCA ATTTTCTGCA TAGCATCAGC AATGAGTCTG
    TACAACTGTC TTGCTGCACT AATTCATAAG ATACCATATG GACAATGCAC GATTGCATGT
    CGTGGCAAAA ACATGGAAGT GAGACTTATT TTTCTCTCTG GACTGTGCAT AGCAGTAGCT
    GTTGTTTGGG CTGTGTTTCG AAATGAAGAC AGGTGGGCTT GGATTTTACA GGATATCTTG
    GGGATTGCTT TCTGTCTGAA TTTAATTAAA ACACTGAAGT TGCCCAACTT CAAGTCATGT
    GTGATACTTC TAGGCCTTCT CCTCCTCTAT GATGTATTTT TTGTTTTCAT AACACCATTC
    ATCACAAAGA ATGGTGAGAG TATCATGGTT GAACTCGCAG CTGGACCTTT TGGAAATAAT
    GAAAAGAATG ATGGAAACTT GGTGGAAGCC ACTGGTCAAC CCTCAGCTCC CCATGAGAAA
    TTGCCAGTAG TCATCAGAGT ACCAAAACTG ATCTATTTCT CAGTAATGAG TGTGTGCCTC
    ATGCCTGTTT CAATATTGGG TTTTGGAGAC ATTATTGTAC CAGGCCTGTT GATTGCATAC
    TGTAGAAGAT TTGATGTTCA GACTGGTTCT TCTTACATAT ACTATGTTTC GTCTACAGTT
    GCCTATGCTA TTGGCATGAT ACTTACATTT GTTGTTCTGG TGCTGATGAA AAAGGGGCAA
    CCTGCTCTCC TCTATTTAGT ACCTTGCACA CTTATTACTG CCTCAGTTGT TGCCTGGAGA
    CGTAAGGAAA TGAAAAAGTT CTGGAAAGGT AACAGCTATC AGATGATGGA CCATTTGGAT
    TGTGCAACAA ATGAAGAAAA CCCTGTGATA TCTGGTGAAC AGATTGTCCA GCAATAA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    CloneID OHu85712
    Clone ID Related Accession (Same CDS sequence) XM_017022680.1
    Accession Version XM_017022680.1 Latest version! Documents for ORF clone product in default vector
    Sequence Information ORF Nucleotide Sequence (Length: 1413bp)
    Protein sequence
    SNP
    Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
    Clone information Clone Map MSDS
    Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
    ORF Insert Method CloneEZ™ Seamless cloning technology
    Insert Structure linear
    Update Date 2019-12-05
    Organism Homo sapiens(human)
    Product signal peptide peptidase-like 2A isoform X2
    Comment Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000015.10) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    ATGGGGCCGC AGCGGCGGCT GTCCCCTGCC GGGGCCGCCC TACTCTGGGG CTTCCTGCTC 
    CAGCTGACAG CCGCTCAGGA AGCAATCTTG CATGCGTCTG GAAATGGCAC AACCAAGGAC
    TACTGCATGC TTTATAACCC TTATTGGACA GCTCTTCCAA GTACCCTAGA AAATGCAACT
    TCCATTAGTT TGATGAATCT GACTTCCACA CCACTATGCA ACCTTTCTGA TATTCCTCCT
    GTTGGCATAA AGAGCAAAGC AGTTGTGGTT CCATGGGGAA GCTGCCATTT TCTTGAAAAA
    GCCAGAATTG CACAGAAAGG AGGTGCTGAA GCAATGTTAG TTGTCAATAA CAGTGTCCTA
    TTTCCTCCCT CAGGTAACAG ATCTGAATTT CCTGATGTGA AAATACTGAT TGCATTTATA
    AGCTACAAAG ACTTTAGAGA TATGAACCAG ACTCTAGGAG ATAACATTAC TGTGAAAATG
    TATTCTCCAT CGTGGCCTAA CTTTGATTAT ACTATGGTGG TTATTTTTGT AATTGCGGTG
    TTCACTGTGG CATTAGGTGG ATACTGGAGT GGACTAGTTG AATTGGAAAA CTTGAAAGCA
    GTGACAACTG AAGATAGAGA AATGAGGAAA AAGAAGGAAG AATATTTAAC TTTTAGTCCT
    CTTACAGTTG TAATATTTGT GGTCATCTGC TGTGTTATGA TGGTCTTACT TTATTTCTTC
    TACAAATGGT TGGTTTATGT TATGATAGCA ATTTTCTGCA TAGCATCAGC AATGAGTCTG
    TACAACTGTC TTGCTGCACT AATTCATAAG ATACCATATG GACAATGCAC GATTGCATGT
    CGTGGCAAAA ACATGGAAGT GAGACTTATT TTTCTCTCTG GACTGTGCAT AGCAGTAGCT
    GTTGTTTGGG CTGTGTTTCG AAATGAAGAC AGGTGGGCTT GGATTTTACA GGATATCTTG
    GGGATTGCTT TCTGTCTGAA TTTAATTAAA ACACTGAAGT TGCCCAACTT CAAGTCATGT
    GTGATACTTC TAGGCCTTCT CCTCCTCTAT GATGTATTTT TTGTTTTCAT AACACCATTC
    ATCACAAAGA ATGGTGAGAG TATCATGGTT GAACTCGCAG CTGGACCTTT TGGAAATAAT
    GAAAAGAATG ATGGAAACTT GGTGGAAGCC ACTGGTCAAC CCTCAGCTCC CCATGAGAAA
    TTGCCAGTAG TCATCAGAGT ACCAAAACTG ATCTATTTCT CAGTAATGAG TGTGTGCCTC
    ATGCCTGTTT CAATATTGGG TTTTGGAGAC ATTATTGTAC CAGGCCTGTT GATTGCATAC
    TGTAGAAGAT TTGATGTTCA GACTGGTTCT TCTTACATAT ACTATGTTTC GTCTACAGTT
    GATGATGGAC CATTTGGATT GTGCAACAAA TGA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    RefSeq XP_016878169.1
    CDS180..1592
    Translation

    Target ORF information:

    RefSeq Version XM_017022680.1
    Organism Homo sapiens(human)
    Definition Homo sapiens signal peptide peptidase like 2A (SPPL2A), transcript variant X2, mRNA.

    Target ORF information:

    Epitope DYKDDDDK
    Bacterial selection AMPR
    Mammalian selection NeoR
    Vector pcDNA3.1+/C-(K)DYK
    XM_017022680.1

    ORF Insert Sequence:

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    ATGGGGCCGC AGCGGCGGCT GTCCCCTGCC GGGGCCGCCC TACTCTGGGG CTTCCTGCTC 
    CAGCTGACAG CCGCTCAGGA AGCAATCTTG CATGCGTCTG GAAATGGCAC AACCAAGGAC
    TACTGCATGC TTTATAACCC TTATTGGACA GCTCTTCCAA GTACCCTAGA AAATGCAACT
    TCCATTAGTT TGATGAATCT GACTTCCACA CCACTATGCA ACCTTTCTGA TATTCCTCCT
    GTTGGCATAA AGAGCAAAGC AGTTGTGGTT CCATGGGGAA GCTGCCATTT TCTTGAAAAA
    GCCAGAATTG CACAGAAAGG AGGTGCTGAA GCAATGTTAG TTGTCAATAA CAGTGTCCTA
    TTTCCTCCCT CAGGTAACAG ATCTGAATTT CCTGATGTGA AAATACTGAT TGCATTTATA
    AGCTACAAAG ACTTTAGAGA TATGAACCAG ACTCTAGGAG ATAACATTAC TGTGAAAATG
    TATTCTCCAT CGTGGCCTAA CTTTGATTAT ACTATGGTGG TTATTTTTGT AATTGCGGTG
    TTCACTGTGG CATTAGGTGG ATACTGGAGT GGACTAGTTG AATTGGAAAA CTTGAAAGCA
    GTGACAACTG AAGATAGAGA AATGAGGAAA AAGAAGGAAG AATATTTAAC TTTTAGTCCT
    CTTACAGTTG TAATATTTGT GGTCATCTGC TGTGTTATGA TGGTCTTACT TTATTTCTTC
    TACAAATGGT TGGTTTATGT TATGATAGCA ATTTTCTGCA TAGCATCAGC AATGAGTCTG
    TACAACTGTC TTGCTGCACT AATTCATAAG ATACCATATG GACAATGCAC GATTGCATGT
    CGTGGCAAAA ACATGGAAGT GAGACTTATT TTTCTCTCTG GACTGTGCAT AGCAGTAGCT
    GTTGTTTGGG CTGTGTTTCG AAATGAAGAC AGGTGGGCTT GGATTTTACA GGATATCTTG
    GGGATTGCTT TCTGTCTGAA TTTAATTAAA ACACTGAAGT TGCCCAACTT CAAGTCATGT
    GTGATACTTC TAGGCCTTCT CCTCCTCTAT GATGTATTTT TTGTTTTCAT AACACCATTC
    ATCACAAAGA ATGGTGAGAG TATCATGGTT GAACTCGCAG CTGGACCTTT TGGAAATAAT
    GAAAAGAATG ATGGAAACTT GGTGGAAGCC ACTGGTCAAC CCTCAGCTCC CCATGAGAAA
    TTGCCAGTAG TCATCAGAGT ACCAAAACTG ATCTATTTCT CAGTAATGAG TGTGTGCCTC
    ATGCCTGTTT CAATATTGGG TTTTGGAGAC ATTATTGTAC CAGGCCTGTT GATTGCATAC
    TGTAGAAGAT TTGATGTTCA GACTGGTTCT TCTTACATAT ACTATGTTTC GTCTACAGTT
    GATGATGGAC CATTTGGATT GTGCAACAAA TGA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    CloneID OHu85713
    Clone ID Related Accession (Same CDS sequence) XM_017022681.1
    Accession Version XM_017022681.1 Latest version! Documents for ORF clone product in default vector
    Sequence Information ORF Nucleotide Sequence (Length: 1359bp)
    Protein sequence
    SNP
    Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
    Clone information Clone Map MSDS
    Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
    ORF Insert Method CloneEZ™ Seamless cloning technology
    Insert Structure linear
    Update Date 2019-12-05
    Organism Homo sapiens(human)
    Product signal peptide peptidase-like 2A isoform X3
    Comment Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000015.10) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    ATGGGGCCGC AGCGGCGGCT GTCCCCTGCC GGGGCCGCCC TACTCTGGGG CTTCCTGCTC 
    CAGCTGACAG CCGCTCAGGA AGCAATCTTG CATGCGTCTG GAAATGGCAC AACCAAGGAC
    TACTGCATGC TTTATAACCC TTATTGGACA GCTCTTCCAA GTACCCTAGA AAATGCAACT
    TCCATTAGTT TGATGAATCT GACTTCCACA CCACTATGCA ACCTTTCTGA TATTCCTCCT
    GTTGGCATAA AGAGCAAAGC AGTTGTGGTT CCATGGGGAA GCTGCCATTT TCTTGAAAAA
    GCCAGAATTG CACAGAAAGG AGGTGCTGAA GCAATGTTAG TTGTCAATAA CAGTGTCCTA
    TTTCCTCCCT CAGGTAACAG ATCTGAATTT CCTGATGTGA AAATACTGAT TGCATTTATA
    AGCTACAAAG ACTTTAGAGA TATGAACCAG ACTCTAGGAG ATAACATTAC TGTGAAAATG
    TATTCTCCAT CGTGGCCTAA CTTTGATTAT ACTATGGTGG TTATTTTTGT AATTGCGGTG
    TTCACTGTGG CATTAGGTGG ATACTGGAGT GGACTAGTTG AATTGGAAAA CTTGAAAGCA
    GTGACAACTG AAGATAGAGA AATGAGGAAA AAGAAGGAAG AATATTTAAC TTTTAGTCCT
    CTTACAGTTG TAATATTTGT GGTCATCTGC TGTGTTATGA TGGTCTTACT TTATTTCTTC
    TACAAATGGT TGGTTTATGT TATGATAGCA ATTTTCTGCA TAGCATCAGC AATGAGTCTG
    TACAACTGTC TTGCTGCACT AATTCATAAG ATACCATATG GACAATGCAC GATTGCATGT
    CGTGGCAAAA ACATGGAAGT GAGACTTATT TTTCTCTCTG GACTGTGCAT AGCAGTAGCT
    GTTGTTTGGG CTGTGTTTCG AAATGAAGAC AGGTGGGCTT GGATTTTACA GGATATCTTG
    GGGATTGCTT TCTGTCTGAA TTTAATTAAA ACACTGAAGT TGCCCAACTT CAAGTCATGT
    GTGATACTTC TAGGCCTTCT CCTCCTCTAT GATGTATTTT TTGTTTTCAT AACACCATTC
    ATCACAAAGA ATGGTGAGAG TATCATGGTT GAACTCGCAG CTGGACCTTT TGGAAATAAT
    GAAAAGTTGC CAGTAGTCAT CAGAGTACCA AAACTGATCT ATTTCTCAGT AATGAGTGTG
    TGCCTCATGC CTGTTTCAAT ATTGGGTTTT GGAGACATTA TTGTACCAGG CCTGTTGATT
    GCATACTGTA GAAGATTTGA TGTTCAGACT GGTTCTTCTT ACATATACTA TGTTTCGTCT
    ACAGTTGATG ATGGACCATT TGGATTGTGC AACAAATGA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    RefSeq XP_016878170.1
    CDS180..1538
    Translation

    Target ORF information:

    RefSeq Version XM_017022681.1
    Organism Homo sapiens(human)
    Definition Homo sapiens signal peptide peptidase like 2A (SPPL2A), transcript variant X3, mRNA.

    Target ORF information:

    Epitope DYKDDDDK
    Bacterial selection AMPR
    Mammalian selection NeoR
    Vector pcDNA3.1+/C-(K)DYK
    XM_017022681.1

    ORF Insert Sequence:

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    ATGGGGCCGC AGCGGCGGCT GTCCCCTGCC GGGGCCGCCC TACTCTGGGG CTTCCTGCTC 
    CAGCTGACAG CCGCTCAGGA AGCAATCTTG CATGCGTCTG GAAATGGCAC AACCAAGGAC
    TACTGCATGC TTTATAACCC TTATTGGACA GCTCTTCCAA GTACCCTAGA AAATGCAACT
    TCCATTAGTT TGATGAATCT GACTTCCACA CCACTATGCA ACCTTTCTGA TATTCCTCCT
    GTTGGCATAA AGAGCAAAGC AGTTGTGGTT CCATGGGGAA GCTGCCATTT TCTTGAAAAA
    GCCAGAATTG CACAGAAAGG AGGTGCTGAA GCAATGTTAG TTGTCAATAA CAGTGTCCTA
    TTTCCTCCCT CAGGTAACAG ATCTGAATTT CCTGATGTGA AAATACTGAT TGCATTTATA
    AGCTACAAAG ACTTTAGAGA TATGAACCAG ACTCTAGGAG ATAACATTAC TGTGAAAATG
    TATTCTCCAT CGTGGCCTAA CTTTGATTAT ACTATGGTGG TTATTTTTGT AATTGCGGTG
    TTCACTGTGG CATTAGGTGG ATACTGGAGT GGACTAGTTG AATTGGAAAA CTTGAAAGCA
    GTGACAACTG AAGATAGAGA AATGAGGAAA AAGAAGGAAG AATATTTAAC TTTTAGTCCT
    CTTACAGTTG TAATATTTGT GGTCATCTGC TGTGTTATGA TGGTCTTACT TTATTTCTTC
    TACAAATGGT TGGTTTATGT TATGATAGCA ATTTTCTGCA TAGCATCAGC AATGAGTCTG
    TACAACTGTC TTGCTGCACT AATTCATAAG ATACCATATG GACAATGCAC GATTGCATGT
    CGTGGCAAAA ACATGGAAGT GAGACTTATT TTTCTCTCTG GACTGTGCAT AGCAGTAGCT
    GTTGTTTGGG CTGTGTTTCG AAATGAAGAC AGGTGGGCTT GGATTTTACA GGATATCTTG
    GGGATTGCTT TCTGTCTGAA TTTAATTAAA ACACTGAAGT TGCCCAACTT CAAGTCATGT
    GTGATACTTC TAGGCCTTCT CCTCCTCTAT GATGTATTTT TTGTTTTCAT AACACCATTC
    ATCACAAAGA ATGGTGAGAG TATCATGGTT GAACTCGCAG CTGGACCTTT TGGAAATAAT
    GAAAAGTTGC CAGTAGTCAT CAGAGTACCA AAACTGATCT ATTTCTCAGT AATGAGTGTG
    TGCCTCATGC CTGTTTCAAT ATTGGGTTTT GGAGACATTA TTGTACCAGG CCTGTTGATT
    GCATACTGTA GAAGATTTGA TGTTCAGACT GGTTCTTCTT ACATATACTA TGTTTCGTCT
    ACAGTTGATG ATGGACCATT TGGATTGTGC AACAAATGA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

  • PubMed

    Substrate determinants of signal peptide peptidase-like 2a (SPPL2a)-mediated intramembrane proteolysis of the invariant chain CD74.
    The Biochemical journal473(10)1405-22(2016 05)
    H?ttl S,Helfrich F,Mentrup T,Held S,Fukumori A,Steiner H,Saftig P,Fluhrer R,Schr?der B


    Signal-peptide-peptidase-like 2a is required for CD74 intramembrane proteolysis in human B cells.
    Biochemical and biophysical research communications451(1)48-53(2014 Aug)
    Schneppenheim J,H?ttl S,Kruchen A,Fluhrer R,M?ller I,Saftig P,Schneppenheim R,Martin CL,Schr?der B


    Regulated intramembrane proteolysis of the frontotemporal lobar degeneration risk factor, TMEM106B, by signal peptide peptidase-like 2a (SPPL2a).
    The Journal of biological chemistry289(28)19670-80(2014 Jul)
    Brady OA,Zhou X,Hu F


    Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease.
    Nature genetics45(12)1452-8(2013 Dec)
    Lambert JC,Ibrahim-Verbaas CA,Harold D,Naj AC,Sims R,Bellenguez C,DeStafano AL,Bis JC,Beecham GW,Grenier-Boley B,Russo G,Thorton-Wells TA,Jones N,Smith AV,Chouraki V,Thomas C,Ikram MA,Zelenika D,Vardarajan BN,Kamatani Y,Lin CF,Gerrish A,Schmidt H,Kunkle B,Dunstan ML,Ruiz A,Bihoreau MT,Choi SH,Reitz C,Pasquier F,Cruchaga C,Craig D,Amin N,Berr C,Lopez OL,De Jager PL,Deramecourt V,Johnston JA,Evans D,Lovestone S,Letenneur L,Mor?n FJ,Rubinsztein DC,Eiriksdottir G,Sleegers K,Goate AM,Fi?vet N,Huentelman MW,Gill M,Brown K,Kamboh MI,Keller L,Barberger-Gateau P,McGuiness B,Larson EB,Green R,Myers AJ,Dufouil C,Todd S,Wallon D,Love S,Rogaeva E,Gallacher J,St George-Hyslop P,Clarimon J,Lleo A,Bayer A,Tsuang DW,Yu L,Tsolaki M,Boss? P,Spalletta G,Proitsi P,Collinge J,Sorbi S,Sanchez-Garcia F,Fox NC,Hardy J,Deniz Naranjo MC,Bosco P,Clarke R,Brayne C,Galimberti D,Mancuso M,Matthews F,,,,,Moebus S,Mecocci P,Del Zompo M,Maier W,Hampel H,Pilotto A,Bullido M,Panza F,Caffarra P,Nacmias B,Gilbert JR,Mayhaus M,Lannefelt L,Hakonarson H,Pichler S,Carrasquillo MM,Ingelsson M,Beekly D,Alvarez V,Zou F,Valladares O,Younkin SG,Coto E,Hamilton-Nelson KL,Gu W,Razquin C,Pastor P,Mateo I,Owen MJ,Faber KM,Jonsson PV,Combarros O,O'Donovan MC,Cantwell LB,Soininen H,Blacker D,Mead S,Mosley TH Jr,Bennett DA,Harris TB,Fratiglioni L,Holmes C,de Bruijn RF,Passmore P,Montine TJ,Bettens K,Rotter JI,Brice A,Morgan K,Foroud TM,Kukull WA,Hannequin D,Powell JF,Nalls MA,Ritchie K,Lunetta KL,Kauwe JS,Boerwinkle E,Riemenschneider M,Boada M,Hiltuenen M,Martin ER,Schmidt R,Rujescu D,Wang LS,Dartigues JF,Mayeux R,Tzourio C,Hofman A,N?then MM,Graff C,Psaty BM,Jones L,Haines JL,Holmans PA,Lathrop M,Pericak-Vance MA,Launer LJ,Farrer LA,van Duijn CM,Van Broeckhoven C,Moskvina V,Seshadri S,Williams J,Schellenberg GD,Amouyel P