CARD6 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	CARD6
Entrez Gene ID	84674
Full Name	caspase recruitment domain family member 6
Synonyms	CINCIN1
General protein information	Preferred Names caspase recruitment domain family member 6 Names caspase recruitment domain-containing protein 6 CARD-containing inhibitor of Nod1 and Cardiak-induced NF-kB activation caspase recruitment domain protein 6
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 5 Map Location: 5p13.1
Summary	This gene encodes a protein that contains a caspase recruitment domain (CARD), an antiparallel six-helical bundle that mediates homotypic protein-protein interactions. The encoded protein is a microtubule-associated protein that has been shown to interact with receptor-interacting protein kinases and positively modulate signal transduction pathways converging on activation of the inducible transcription factor NF-kB. [provided by RefSeq, Jul 2008].
Disorder MIM:	609986

mRNA and Protein(s)

mRNA	Protein	Name
XM_017009989.1	XP_016865478.1	caspase recruitment domain-containing protein 6 isoform X1
XM_017009990.2	XP_016865479.1	caspase recruitment domain-containing protein 6 isoform X2
XM_017009990.1	XP_016865479.1	caspase recruitment domain-containing protein 6 isoform X2
NM_032587.3	NP_115976.2	caspase recruitment domain-containing protein 6
NM_032587.4	NP_115976.2	caspase recruitment domain-containing protein 6

Pathways from BioSystems

Homologies

Homo sapiens (human)	CARD6	NP_115976.2
	CARD6	XP_001086772.1
Canis lupus familiaris (dog)	CARD6	XP_005619425.1
Mus musculus (house mouse)	Card6	NP_001156610.1
Rattus norvegicus (Norway rat)	Card6	NP_001099883.1
Pan troglodytes (chimpanzee)	CARD6	XP_517788.2
Bos taurus (cattle)	CARD6	NP_001179450.1

Gene Ontology
Bibliography

Related articles in PubMed

NOD-like receptor signaling and inflammasome-related pathways are highlighted in psoriatic epidermis.
Tervaniemi MH, Katayama S, Skoog T, Siitonen HA, Vuola J, Nuutila K, Sormunen R, Johnsson A, Linnarsson S, Suomela S, Kankuri E, Kere J, Elomaa O
Scientific reports622745(2016 Mar)

Expression of CARD6, an NF-kappaB activator, in gastric, colorectal and oesophageal cancers.
Kim SS, Ahn CH, Kang MR, Kim YR, Kim HS, Yoo NJ, Lee SH
Pathology42(1)50-3(2010 Jan)

CARD tricks: controlling the interactions of CARD6 with RICK and microtubules.
Dufner A, Mak TW
Cell cycle (Georgetown, Tex.)5(8)797-800(2006 Apr)

Caspase recruitment domain protein 6 is a microtubule-interacting protein that positively modulates NF-kappaB activation.
Dufner A, Pownall S, Mak TW
Proceedings of the National Academy of Sciences of the United States of America103(4)988-93(2006 Jan)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Data show that NOD-like receptor signaling genes NOD2, PYCARD, CARD6, and IFI16 are upregulated in psoriatic epidermis.
Title: NOD-like receptor signaling and inflammasome-related pathways are highlighted in psoriatic epidermis.

The increased expression of CARD6 in esophageal squamous cell carcinoma,gastric and colorectal adenocarcinoma suggested that neoexpression of CARD6 might be related to activation of NF-kappaB pathway.
Title: Expression of CARD6, an NF-kappaB activator, in gastric, colorectal and oesophageal cancers.

review of the regulation of interactions of CARD6 with RICK and microtubules [review]
Title: CARD tricks: controlling the interactions of CARD6 with RICK and microtubules.

CARD6 is a regulator of NF-kappaB activation that modulates the functions of RICK protein
Title: Caspase recruitment domain protein 6 is a microtubule-interacting protein that positively modulates NF-kappaB activation.

identification as a modulator of NF-kappa B activation by Nod1- and Cardiak-mediated pathways
Title: CARD6 is a modulator of NF-kappa B activation by Nod1- and Cardiak-mediated pathways.

The following CARD6 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the CARD6 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu29979	NM_032587.4 Latest version!	Homo sapiens caspase recruitment domain family member 6 (CARD6), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$274.50-$384.30 $549.00
OHu96166	XM_017009990.2 Latest version!	Homo sapiens caspase recruitment domain family member 6 (CARD6), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	10-12	$391.30 $559.00
OHu96165	XM_017009989.1 Latest version!	Homo sapiens caspase recruitment domain family member 6 (CARD6), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$475.30 $679.00
View Old Accession Versions >>
OHu96166	XM_017009990.1	Homo sapiens caspase recruitment domain family member 6 (CARD6), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	10-12	$391.30 $559.00
OHu29979	NM_032587.3	Homo sapiens caspase recruitment domain family member 6 (CARD6), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$274.50-$384.30 $549.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

CARD6 ( NM_032587.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_115976.2 Homo sapiens caspase recruitment domain family member 6 (CARD6), mRNA.

Price & Availability↑

CloneID	OHu29979
Clone ID Related Accession (Same CDS sequence)	NM_032587.3 , NM_032587.4
Accession Version	NM_032587.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3114bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-01
Organism	Homo sapiens(human)
Product	caspase recruitment domain-containing protein 6
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AF356193.1, BC093825.1 and AC026732.5. On Mar 27, 2006 this sequence version replaced NM_032587.2. ##Evidence-Data-START## Transcript exon combination :: AF356193.1, SRR1660807.65126.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCTACCG AGAGTACTCC CTCAGAGATC ATAGAAAGAG AAAGAAAAAA GTTGCTTGAA 
ATCCTTCAAC ATGATCCTGA TTCTATCTTA GACACGTTAA CTTCTCGGAG GCTGATTTCT 
GAGGAAGAGT ATGAGACTCT GGAGAATGTT ACAGATCTCC TGAAGAAAAG TCGGAAGCTG 
TTAATTTTGG TACAGAAAAA GGGAGAGGCG ACCTGTCAGC ATTTTCTCAA GTGTTTATTT 
AGTACTTTTC CACAGTCAGC TGCCATTTGC GGCTTAAGGC ATGAAGTTTT AAAACATGAG 
AATACAGTAC CTCCTCAATC TATGGGGGCA AGCAGTAATT CAGAAGATGC TTTTTCTCCT 
GGAATAAAAC AGCCTGAAGC CCCTGAGATC ACAGTGTTCT TCAGTGAGAA GGAACACTTG 
GATTTGGAAA CCTCTGAGTT TTTCAGGGAC AAGAAAACTA GTTATAGGGA AACAGCTTTG 
TCTGCCAGGA AGAATGAGAA GGAATATGAC ACACCAGAAG TCACATTATC ATATTCAGTT 
GAGAAAGTTG GATGTGAAGT TCCAGCAACT ATTACATATA TAAAAGATGG ACAGAGATAT 
GAGGAGCTAG ATGATTCTTT ATACTTAGGA AAAGAGGAAT ATCTAGGATC TGTTGACACC 
CCTGAAGATG CAGAAGCCAC TGTGGAAGAG GAGGTTTATG ATGACCCAGA GCACGTTGGA 
TATGATGGTG AAGAGGACTT CGAGAATTCA GAAACCACAG AGTTCTCTGG TGAAGAACCA 
AGTTATGAGG GATCAGAAAC CAGCCTTTCA TTGGAGGAGG AACAGGAGAA AAGTATAGAA 
GAAAGAAAAA AGGTGTTTAA AGATGTCCTG TTATGTTTGA ACATGGATAG AAGCAGAAAG 
GTTCTGCCAG ATTTTGTTAA ACAATTCTCC TTAGATCGAG GATGTAAGTG GACCCCTGAG 
AGTCCAGGAG ACTTAGCCTG GAATTTCCTG ATGAAAGTTC AAGCACGAGA TGTGACGGCT 
AGGGATTCAA TCCTCAGTCA CAAGGTTCTG GATGAAGATA GCAAGGAGGA TTTGCTGGCT 
GGAGTGGAGA ATTTGGAAAT TCGAGACATA CAAACCATTA ATCCCCTTGA CGTGCTTTGT 
GCCACCATGC TGTGTTCAGA TAGCTCTTTG CAACGCCAAG TCATGTCAAA CATGTATCAG 
TGCCAGTTTG CTCTTCCCCT GCTACTGCCA GATGCAGAAA ACAACAAAAG CATCTTAATG 
CTGGGGGCCA TGAAAGACAT TGTGAAGAAG CAGTCAACAC AGTTTTCAGG GGGGCCTACA 
GAGGATACAG AAAAGTTTCT GACTCTCATG AAGATGCCTG TCATCTCTTT TGTGCGTCTA 
GGATACTGTA GCTTCTCTAA GTCCAGAATC CTCAACACAC TTCTCAGCCC TGCCCAGTTG 
AAATTACACA AAATCTTTCT TCATCAAGAT TTGCCTCTTT TGGTGCTTCC CCGGCAAATC 
TCTGATGGCC TGGTTGAGAT AACATGGTGT TTTCCTGATA GCGATGATAG AAAGGAAAAC 
CCCTTTTTCC AAAAGCCTGT TGCTCTGGCT AATCTCCGTG GAAATCTAGA AAGCTTTTGG 
ACTCAGTTTG GTTTTTTGAT GGAAGTTTCT TCAGCTGTGT TTTTTTTCAC TGACTGTTTA 
GGTGAGAAGG AATGGGACTT GCTAATGTTT TTAGGAGAGG CTGCCATTGA AAGATGCTAC 
TTTGTTCTCA GTTCCCAAGC CAGGGAGAGT GAAGAGGCTC AAATTTTTCA GAGGATACTG 
AACTTGAAGC CAGCACAGCT ACTGTTTTGG GAGAGGGGAG ATGCTGGGGA TAGAAGGAAG 
AACATGGAGG GCCTTCAAGC TGCCCTCCAG GAAGTGATGT TCTCTTCTTG CCTCAGATGT 
GTGTCTGTGG AGGATATGGC CGCCCTGGCC AGGGAGCTGG GGATTCAGGT AGATGAAGAC 
TTTGAAAACA CTCAGAGAAT TCAAGTTTCC TCTGGAGAAA ACATGGCTGG GACAGCTGAA 
GGTGAGGGTC AGCAAAGACA CAGTCAGCTA AAAAGCTCAT CTAAAAGCCA GGCTCTAATG 
CCAATTCAAG AGCCTGGGAC TCAATGTGAG CTCAGCCAGA ATCTTCAGAA TCTCTATGGT 
ACCCCAGTAT TCAGGCCTGT TCTAGAGAAC TCCTGGCTCT TTCCAACCAG AATTGGAGGT 
AACTTTAACC ATGTTTCCTT GAAAGCCTCC TGGGTTATGG GCCGCCCCTT TGGGTCAGAG 
CAGAGGCCTA AGTGGTTCCA TCCTTTGCCT TTTCAGAATG CAGGGGCCCA GGGCCGAGGT 
AAAAGTTTTG GTATTCAATC CTTCCATCCC CAGATATTTT ATTCAGGTGA AAGATTCATG 
AAATTTTCCA GAGTTGCTCG GGGATGTCAC TCGAATGGAA CATTTGGGAG ACTGCCAAGA 
CCCATTTGTC AGCATGTACA GGCCTGCCCT GAGAGACCAC AAATGATGGG AACTCTTGAA 
AGGTCTAGGG CAGTAGCCTC CAAGATAGGT CACTCCTATT CCCTGGATTC ACAGCCAGCA 
AGAGCAGTAG GGAAGCCATG GCCTCAGCAA GCTTGCACCA GGGTAACAGA GTTAACTGAA 
GCAACTGGAA AACTGATAAG AACATCCCAT ATTGGAAAGC CTCACCCTCA GTCCTTTCAA 
CCAGCAGCAG CCACACAAAA ACTAAGACCT GCTTCTCAGC AAGGAGTCCA GATGAAGACA 
CAAGGTGGGG CTTCAAATCC AGCTCTCCAA ATAGGGTCCC ATCCCATGTG CAAGAGCTCT 
CAGTTCAAAT CCGATCAGTC CAACCCATCC ACAGTCAAAC ACTCCCAGCC TAAACCCTTC 
CATTCTGTGC CCTCTCAACC TAAATCCTCT CAGACAAAAT CCTGTCAGTC CCAGCCCTCC 
CAAACTAAAC CTTCTCCATG CAAATCTACT CAGCCTAAGC CAAGCCAGCC CTGGCCTCCC 
CAGTCTAAGC CTTCTCAGCC CAGACCCCCT CAACCTAAGT CATCCTCAAC CAATCCTTCA 
CAAGCTAAGG CACACCACTC AAAAGCAGGG CAGAAGAGGG GAGGGAAGCA TTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_115976.2
CDS	76..3189
Translation	MATESTPSEIIERERKKLLEILQHDPDSILDTLTSRRLISEEEYETLENVTDLLKKSRKLLILVQKKGEATCQHFLKCLFSTFPQSAAICGLRHEVLKHENTVPPQSMGASSNSEDAFSPGIKQPEAPEITVFFSEKEHLDLETSEFFRDKKTSYRETALSARKNEKEYDTPEVTLSYSVEKVGCEVPATITYIKDGQRYEELDDSLYLGKEEYLGSVDTPEDAEATVEEEVYDDPEHVGYDGEEDFENSETTEFSGEEPSYEGSETSLSLEEEQEKSIEERKKVFKDVLLCLNMDRSRKVLPDFVKQFSLDRGCKWTPESPGDLAWNFLMKVQARDVTARDSILSHKVLDEDSKEDLLAGVENLEIRDIQTINPLDVLCATMLCSDSSLQRQVMSNMYQCQFALPLLLPDAENNKSILMLGAMKDIVKKQSTQFSGGPTEDTEKFLTLMKMPVISFVRLGYCSFSKSRILNTLLSPAQLKLHKIFLHQDLPLLVLPRQISDGLVEITWCFPDSDDRKENPFFQKPVALANLRGNLESFWTQFGFLMEVSSAVFFFTDCLGEKEWDLLMFLGEAAIERCYFVLSSQARESEEAQIFQRILNLKPAQLLFWERGDAGDRRKNMEGLQAALQEVMFSSCLRCVSVEDMAALARELGIQVDEDFENTQRIQVSSGENMAGTAEGEGQQRHSQLKSSSKSQALMPIQEPGTQCELSQNLQNLYGTPVFRPVLENSWLFPTRIGGNFNHVSLKASWVMGRPFGSEQRPKWFHPLPFQNAGAQGRGKSFGIQSFHPQIFYSGERFMKFSRVARGCHSNGTFGRLPRPICQHVQACPERPQMMGTLERSRAVASKIGHSYSLDSQPARAVGKPWPQQACTRVTELTEATGKLIRTSHIGKPHPQSFQPAAATQKLRPASQQGVQMKTQGGASNPALQIGSHPMCKSSQFKSDQSNPSTVKHSQPKPFHSVPSQPKSSQTKSCQSQPSQTKPSPCKSTQPKPSQPWPPQSKPSQPRPPQPKSSSTNPSQAKAHHSKAGQKRGGKH

Target ORF information:

RefSeq Version	NM_032587.3
Organism	Homo sapiens(human)
Definition	Homo sapiens caspase recruitment domain family member 6 (CARD6), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_032587.3

ORF Insert Sequence:

ATGGCTACCG AGAGTACTCC CTCAGAGATC ATAGAAAGAG AAAGAAAAAA GTTGCTTGAA 
ATCCTTCAAC ATGATCCTGA TTCTATCTTA GACACGTTAA CTTCTCGGAG GCTGATTTCT 
GAGGAAGAGT ATGAGACTCT GGAGAATGTT ACAGATCTCC TGAAGAAAAG TCGGAAGCTG 
TTAATTTTGG TACAGAAAAA GGGAGAGGCG ACCTGTCAGC ATTTTCTCAA GTGTTTATTT 
AGTACTTTTC CACAGTCAGC TGCCATTTGC GGCTTAAGGC ATGAAGTTTT AAAACATGAG 
AATACAGTAC CTCCTCAATC TATGGGGGCA AGCAGTAATT CAGAAGATGC TTTTTCTCCT 
GGAATAAAAC AGCCTGAAGC CCCTGAGATC ACAGTGTTCT TCAGTGAGAA GGAACACTTG 
GATTTGGAAA CCTCTGAGTT TTTCAGGGAC AAGAAAACTA GTTATAGGGA AACAGCTTTG 
TCTGCCAGGA AGAATGAGAA GGAATATGAC ACACCAGAAG TCACATTATC ATATTCAGTT 
GAGAAAGTTG GATGTGAAGT TCCAGCAACT ATTACATATA TAAAAGATGG ACAGAGATAT 
GAGGAGCTAG ATGATTCTTT ATACTTAGGA AAAGAGGAAT ATCTAGGATC TGTTGACACC 
CCTGAAGATG CAGAAGCCAC TGTGGAAGAG GAGGTTTATG ATGACCCAGA GCACGTTGGA 
TATGATGGTG AAGAGGACTT CGAGAATTCA GAAACCACAG AGTTCTCTGG TGAAGAACCA 
AGTTATGAGG GATCAGAAAC CAGCCTTTCA TTGGAGGAGG AACAGGAGAA AAGTATAGAA 
GAAAGAAAAA AGGTGTTTAA AGATGTCCTG TTATGTTTGA ACATGGATAG AAGCAGAAAG 
GTTCTGCCAG ATTTTGTTAA ACAATTCTCC TTAGATCGAG GATGTAAGTG GACCCCTGAG 
AGTCCAGGAG ACTTAGCCTG GAATTTCCTG ATGAAAGTTC AAGCACGAGA TGTGACGGCT 
AGGGATTCAA TCCTCAGTCA CAAGGTTCTG GATGAAGATA GCAAGGAGGA TTTGCTGGCT 
GGAGTGGAGA ATTTGGAAAT TCGAGACATA CAAACCATTA ATCCCCTTGA CGTGCTTTGT 
GCCACCATGC TGTGTTCAGA TAGCTCTTTG CAACGCCAAG TCATGTCAAA CATGTATCAG 
TGCCAGTTTG CTCTTCCCCT GCTACTGCCA GATGCAGAAA ACAACAAAAG CATCTTAATG 
CTGGGGGCCA TGAAAGACAT TGTGAAGAAG CAGTCAACAC AGTTTTCAGG GGGGCCTACA 
GAGGATACAG AAAAGTTTCT GACTCTCATG AAGATGCCTG TCATCTCTTT TGTGCGTCTA 
GGATACTGTA GCTTCTCTAA GTCCAGAATC CTCAACACAC TTCTCAGCCC TGCCCAGTTG 
AAATTACACA AAATCTTTCT TCATCAAGAT TTGCCTCTTT TGGTGCTTCC CCGGCAAATC 
TCTGATGGCC TGGTTGAGAT AACATGGTGT TTTCCTGATA GCGATGATAG AAAGGAAAAC 
CCCTTTTTCC AAAAGCCTGT TGCTCTGGCT AATCTCCGTG GAAATCTAGA AAGCTTTTGG 
ACTCAGTTTG GTTTTTTGAT GGAAGTTTCT TCAGCTGTGT TTTTTTTCAC TGACTGTTTA 
GGTGAGAAGG AATGGGACTT GCTAATGTTT TTAGGAGAGG CTGCCATTGA AAGATGCTAC 
TTTGTTCTCA GTTCCCAAGC CAGGGAGAGT GAAGAGGCTC AAATTTTTCA GAGGATACTG 
AACTTGAAGC CAGCACAGCT ACTGTTTTGG GAGAGGGGAG ATGCTGGGGA TAGAAGGAAG 
AACATGGAGG GCCTTCAAGC TGCCCTCCAG GAAGTGATGT TCTCTTCTTG CCTCAGATGT 
GTGTCTGTGG AGGATATGGC CGCCCTGGCC AGGGAGCTGG GGATTCAGGT AGATGAAGAC 
TTTGAAAACA CTCAGAGAAT TCAAGTTTCC TCTGGAGAAA ACATGGCTGG GACAGCTGAA 
GGTGAGGGTC AGCAAAGACA CAGTCAGCTA AAAAGCTCAT CTAAAAGCCA GGCTCTAATG 
CCAATTCAAG AGCCTGGGAC TCAATGTGAG CTCAGCCAGA ATCTTCAGAA TCTCTATGGT 
ACCCCAGTAT TCAGGCCTGT TCTAGAGAAC TCCTGGCTCT TTCCAACCAG AATTGGAGGT 
AACTTTAACC ATGTTTCCTT GAAAGCCTCC TGGGTTATGG GCCGCCCCTT TGGGTCAGAG 
CAGAGGCCTA AGTGGTTCCA TCCTTTGCCT TTTCAGAATG CAGGGGCCCA GGGCCGAGGT 
AAAAGTTTTG GTATTCAATC CTTCCATCCC CAGATATTTT ATTCAGGTGA AAGATTCATG 
AAATTTTCCA GAGTTGCTCG GGGATGTCAC TCGAATGGAA CATTTGGGAG ACTGCCAAGA 
CCCATTTGTC AGCATGTACA GGCCTGCCCT GAGAGACCAC AAATGATGGG AACTCTTGAA 
AGGTCTAGGG CAGTAGCCTC CAAGATAGGT CACTCCTATT CCCTGGATTC ACAGCCAGCA 
AGAGCAGTAG GGAAGCCATG GCCTCAGCAA GCTTGCACCA GGGTAACAGA GTTAACTGAA 
GCAACTGGAA AACTGATAAG AACATCCCAT ATTGGAAAGC CTCACCCTCA GTCCTTTCAA 
CCAGCAGCAG CCACACAAAA ACTAAGACCT GCTTCTCAGC AAGGAGTCCA GATGAAGACA 
CAAGGTGGGG CTTCAAATCC AGCTCTCCAA ATAGGGTCCC ATCCCATGTG CAAGAGCTCT 
CAGTTCAAAT CCGATCAGTC CAACCCATCC ACAGTCAAAC ACTCCCAGCC TAAACCCTTC 
CATTCTGTGC CCTCTCAACC TAAATCCTCT CAGACAAAAT CCTGTCAGTC CCAGCCCTCC 
CAAACTAAAC CTTCTCCATG CAAATCTACT CAGCCTAAGC CAAGCCAGCC CTGGCCTCCC 
CAGTCTAAGC CTTCTCAGCC CAGACCCCCT CAACCTAAGT CATCCTCAAC CAATCCTTCA 
CAAGCTAAGG CACACCACTC AAAAGCAGGG CAGAAGAGGG GAGGGAAGCA TTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CARD6 ( NM_032587.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_115976.2 Homo sapiens caspase recruitment domain family member 6 (CARD6), mRNA.

Price & Availability↑

CloneID	OHu29979
Clone ID Related Accession (Same CDS sequence)	NM_032587.3 , NM_032587.4
Accession Version	NM_032587.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3114bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-30
Organism	Homo sapiens(human)
Product	caspase recruitment domain-containing protein 6
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC093825.1 and AC026732.5. On Nov 22, 2018 this sequence version replaced NM_032587.3. ##Evidence-Data-START## Transcript exon combination :: AF356193.1, SRR1660807.65126.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000254691.10/ ENSP00000254691.5 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGCTACCG AGAGTACTCC CTCAGAGATC ATAGAAAGAG AAAGAAAAAA GTTGCTTGAA 
ATCCTTCAAC ATGATCCTGA TTCTATCTTA GACACGTTAA CTTCTCGGAG GCTGATTTCT 
GAGGAAGAGT ATGAGACTCT GGAGAATGTT ACAGATCTCC TGAAGAAAAG TCGGAAGCTG 
TTAATTTTGG TACAGAAAAA GGGAGAGGCG ACCTGTCAGC ATTTTCTCAA GTGTTTATTT 
AGTACTTTTC CACAGTCAGC TGCCATTTGC GGCTTAAGGC ATGAAGTTTT AAAACATGAG 
AATACAGTAC CTCCTCAATC TATGGGGGCA AGCAGTAATT CAGAAGATGC TTTTTCTCCT 
GGAATAAAAC AGCCTGAAGC CCCTGAGATC ACAGTGTTCT TCAGTGAGAA GGAACACTTG 
GATTTGGAAA CCTCTGAGTT TTTCAGGGAC AAGAAAACTA GTTATAGGGA AACAGCTTTG 
TCTGCCAGGA AGAATGAGAA GGAATATGAC ACACCAGAAG TCACATTATC ATATTCAGTT 
GAGAAAGTTG GATGTGAAGT TCCAGCAACT ATTACATATA TAAAAGATGG ACAGAGATAT 
GAGGAGCTAG ATGATTCTTT ATACTTAGGA AAAGAGGAAT ATCTAGGATC TGTTGACACC 
CCTGAAGATG CAGAAGCCAC TGTGGAAGAG GAGGTTTATG ATGACCCAGA GCACGTTGGA 
TATGATGGTG AAGAGGACTT CGAGAATTCA GAAACCACAG AGTTCTCTGG TGAAGAACCA 
AGTTATGAGG GATCAGAAAC CAGCCTTTCA TTGGAGGAGG AACAGGAGAA AAGTATAGAA 
GAAAGAAAAA AGGTGTTTAA AGATGTCCTG TTATGTTTGA ACATGGATAG AAGCAGAAAG 
GTTCTGCCAG ATTTTGTTAA ACAATTCTCC TTAGATCGAG GATGTAAGTG GACCCCTGAG 
AGTCCAGGAG ACTTAGCCTG GAATTTCCTG ATGAAAGTTC AAGCACGAGA TGTGACGGCT 
AGGGATTCAA TCCTCAGTCA CAAGGTTCTG GATGAAGATA GCAAGGAGGA TTTGCTGGCT 
GGAGTGGAGA ATTTGGAAAT TCGAGACATA CAAACCATTA ATCCCCTTGA CGTGCTTTGT 
GCCACCATGC TGTGTTCAGA TAGCTCTTTG CAACGCCAAG TCATGTCAAA CATGTATCAG 
TGCCAGTTTG CTCTTCCCCT GCTACTGCCA GATGCAGAAA ACAACAAAAG CATCTTAATG 
CTGGGGGCCA TGAAAGACAT TGTGAAGAAG CAGTCAACAC AGTTTTCAGG GGGGCCTACA 
GAGGATACAG AAAAGTTTCT GACTCTCATG AAGATGCCTG TCATCTCTTT TGTGCGTCTA 
GGATACTGTA GCTTCTCTAA GTCCAGAATC CTCAACACAC TTCTCAGCCC TGCCCAGTTG 
AAATTACACA AAATCTTTCT TCATCAAGAT TTGCCTCTTT TGGTGCTTCC CCGGCAAATC 
TCTGATGGCC TGGTTGAGAT AACATGGTGT TTTCCTGATA GCGATGATAG AAAGGAAAAC 
CCCTTTTTCC AAAAGCCTGT TGCTCTGGCT AATCTCCGTG GAAATCTAGA AAGCTTTTGG 
ACTCAGTTTG GTTTTTTGAT GGAAGTTTCT TCAGCTGTGT TTTTTTTCAC TGACTGTTTA 
GGTGAGAAGG AATGGGACTT GCTAATGTTT TTAGGAGAGG CTGCCATTGA AAGATGCTAC 
TTTGTTCTCA GTTCCCAAGC CAGGGAGAGT GAAGAGGCTC AAATTTTTCA GAGGATACTG 
AACTTGAAGC CAGCACAGCT ACTGTTTTGG GAGAGGGGAG ATGCTGGGGA TAGAAGGAAG 
AACATGGAGG GCCTTCAAGC TGCCCTCCAG GAAGTGATGT TCTCTTCTTG CCTCAGATGT 
GTGTCTGTGG AGGATATGGC CGCCCTGGCC AGGGAGCTGG GGATTCAGGT AGATGAAGAC 
TTTGAAAACA CTCAGAGAAT TCAAGTTTCC TCTGGAGAAA ACATGGCTGG GACAGCTGAA 
GGTGAGGGTC AGCAAAGACA CAGTCAGCTA AAAAGCTCAT CTAAAAGCCA GGCTCTAATG 
CCAATTCAAG AGCCTGGGAC TCAATGTGAG CTCAGCCAGA ATCTTCAGAA TCTCTATGGT 
ACCCCAGTAT TCAGGCCTGT TCTAGAGAAC TCCTGGCTCT TTCCAACCAG AATTGGAGGT 
AACTTTAACC ATGTTTCCTT GAAAGCCTCC TGGGTTATGG GCCGCCCCTT TGGGTCAGAG 
CAGAGGCCTA AGTGGTTCCA TCCTTTGCCT TTTCAGAATG CAGGGGCCCA GGGCCGAGGT 
AAAAGTTTTG GTATTCAATC CTTCCATCCC CAGATATTTT ATTCAGGTGA AAGATTCATG 
AAATTTTCCA GAGTTGCTCG GGGATGTCAC TCGAATGGAA CATTTGGGAG ACTGCCAAGA 
CCCATTTGTC AGCATGTACA GGCCTGCCCT GAGAGACCAC AAATGATGGG AACTCTTGAA 
AGGTCTAGGG CAGTAGCCTC CAAGATAGGT CACTCCTATT CCCTGGATTC ACAGCCAGCA 
AGAGCAGTAG GGAAGCCATG GCCTCAGCAA GCTTGCACCA GGGTAACAGA GTTAACTGAA 
GCAACTGGAA AACTGATAAG AACATCCCAT ATTGGAAAGC CTCACCCTCA GTCCTTTCAA 
CCAGCAGCAG CCACACAAAA ACTAAGACCT GCTTCTCAGC AAGGAGTCCA GATGAAGACA 
CAAGGTGGGG CTTCAAATCC AGCTCTCCAA ATAGGGTCCC ATCCCATGTG CAAGAGCTCT 
CAGTTCAAAT CCGATCAGTC CAACCCATCC ACAGTCAAAC ACTCCCAGCC TAAACCCTTC 
CATTCTGTGC CCTCTCAACC TAAATCCTCT CAGACAAAAT CCTGTCAGTC CCAGCCCTCC 
CAAACTAAAC CTTCTCCATG CAAATCTACT CAGCCTAAGC CAAGCCAGCC CTGGCCTCCC 
CAGTCTAAGC CTTCTCAGCC CAGACCCCCT CAACCTAAGT CATCCTCAAC CAATCCTTCA 
CAAGCTAAGG CACACCACTC AAAAGCAGGG CAGAAGAGGG GAGGGAAGCA TTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_115976.2
CDS	17..3130
Translation	MATESTPSEIIERERKKLLEILQHDPDSILDTLTSRRLISEEEYETLENVTDLLKKSRKLLILVQKKGEATCQHFLKCLFSTFPQSAAICGLRHEVLKHENTVPPQSMGASSNSEDAFSPGIKQPEAPEITVFFSEKEHLDLETSEFFRDKKTSYRETALSARKNEKEYDTPEVTLSYSVEKVGCEVPATITYIKDGQRYEELDDSLYLGKEEYLGSVDTPEDAEATVEEEVYDDPEHVGYDGEEDFENSETTEFSGEEPSYEGSETSLSLEEEQEKSIEERKKVFKDVLLCLNMDRSRKVLPDFVKQFSLDRGCKWTPESPGDLAWNFLMKVQARDVTARDSILSHKVLDEDSKEDLLAGVENLEIRDIQTINPLDVLCATMLCSDSSLQRQVMSNMYQCQFALPLLLPDAENNKSILMLGAMKDIVKKQSTQFSGGPTEDTEKFLTLMKMPVISFVRLGYCSFSKSRILNTLLSPAQLKLHKIFLHQDLPLLVLPRQISDGLVEITWCFPDSDDRKENPFFQKPVALANLRGNLESFWTQFGFLMEVSSAVFFFTDCLGEKEWDLLMFLGEAAIERCYFVLSSQARESEEAQIFQRILNLKPAQLLFWERGDAGDRRKNMEGLQAALQEVMFSSCLRCVSVEDMAALARELGIQVDEDFENTQRIQVSSGENMAGTAEGEGQQRHSQLKSSSKSQALMPIQEPGTQCELSQNLQNLYGTPVFRPVLENSWLFPTRIGGNFNHVSLKASWVMGRPFGSEQRPKWFHPLPFQNAGAQGRGKSFGIQSFHPQIFYSGERFMKFSRVARGCHSNGTFGRLPRPICQHVQACPERPQMMGTLERSRAVASKIGHSYSLDSQPARAVGKPWPQQACTRVTELTEATGKLIRTSHIGKPHPQSFQPAAATQKLRPASQQGVQMKTQGGASNPALQIGSHPMCKSSQFKSDQSNPSTVKHSQPKPFHSVPSQPKSSQTKSCQSQPSQTKPSPCKSTQPKPSQPWPPQSKPSQPRPPQPKSSSTNPSQAKAHHSKAGQKRGGKH

Target ORF information:

RefSeq Version	NM_032587.4
Organism	Homo sapiens(human)
Definition	Homo sapiens caspase recruitment domain family member 6 (CARD6), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_032587.4

ORF Insert Sequence:

ATGGCTACCG AGAGTACTCC CTCAGAGATC ATAGAAAGAG AAAGAAAAAA GTTGCTTGAA 
ATCCTTCAAC ATGATCCTGA TTCTATCTTA GACACGTTAA CTTCTCGGAG GCTGATTTCT 
GAGGAAGAGT ATGAGACTCT GGAGAATGTT ACAGATCTCC TGAAGAAAAG TCGGAAGCTG 
TTAATTTTGG TACAGAAAAA GGGAGAGGCG ACCTGTCAGC ATTTTCTCAA GTGTTTATTT 
AGTACTTTTC CACAGTCAGC TGCCATTTGC GGCTTAAGGC ATGAAGTTTT AAAACATGAG 
AATACAGTAC CTCCTCAATC TATGGGGGCA AGCAGTAATT CAGAAGATGC TTTTTCTCCT 
GGAATAAAAC AGCCTGAAGC CCCTGAGATC ACAGTGTTCT TCAGTGAGAA GGAACACTTG 
GATTTGGAAA CCTCTGAGTT TTTCAGGGAC AAGAAAACTA GTTATAGGGA AACAGCTTTG 
TCTGCCAGGA AGAATGAGAA GGAATATGAC ACACCAGAAG TCACATTATC ATATTCAGTT 
GAGAAAGTTG GATGTGAAGT TCCAGCAACT ATTACATATA TAAAAGATGG ACAGAGATAT 
GAGGAGCTAG ATGATTCTTT ATACTTAGGA AAAGAGGAAT ATCTAGGATC TGTTGACACC 
CCTGAAGATG CAGAAGCCAC TGTGGAAGAG GAGGTTTATG ATGACCCAGA GCACGTTGGA 
TATGATGGTG AAGAGGACTT CGAGAATTCA GAAACCACAG AGTTCTCTGG TGAAGAACCA 
AGTTATGAGG GATCAGAAAC CAGCCTTTCA TTGGAGGAGG AACAGGAGAA AAGTATAGAA 
GAAAGAAAAA AGGTGTTTAA AGATGTCCTG TTATGTTTGA ACATGGATAG AAGCAGAAAG 
GTTCTGCCAG ATTTTGTTAA ACAATTCTCC TTAGATCGAG GATGTAAGTG GACCCCTGAG 
AGTCCAGGAG ACTTAGCCTG GAATTTCCTG ATGAAAGTTC AAGCACGAGA TGTGACGGCT 
AGGGATTCAA TCCTCAGTCA CAAGGTTCTG GATGAAGATA GCAAGGAGGA TTTGCTGGCT 
GGAGTGGAGA ATTTGGAAAT TCGAGACATA CAAACCATTA ATCCCCTTGA CGTGCTTTGT 
GCCACCATGC TGTGTTCAGA TAGCTCTTTG CAACGCCAAG TCATGTCAAA CATGTATCAG 
TGCCAGTTTG CTCTTCCCCT GCTACTGCCA GATGCAGAAA ACAACAAAAG CATCTTAATG 
CTGGGGGCCA TGAAAGACAT TGTGAAGAAG CAGTCAACAC AGTTTTCAGG GGGGCCTACA 
GAGGATACAG AAAAGTTTCT GACTCTCATG AAGATGCCTG TCATCTCTTT TGTGCGTCTA 
GGATACTGTA GCTTCTCTAA GTCCAGAATC CTCAACACAC TTCTCAGCCC TGCCCAGTTG 
AAATTACACA AAATCTTTCT TCATCAAGAT TTGCCTCTTT TGGTGCTTCC CCGGCAAATC 
TCTGATGGCC TGGTTGAGAT AACATGGTGT TTTCCTGATA GCGATGATAG AAAGGAAAAC 
CCCTTTTTCC AAAAGCCTGT TGCTCTGGCT AATCTCCGTG GAAATCTAGA AAGCTTTTGG 
ACTCAGTTTG GTTTTTTGAT GGAAGTTTCT TCAGCTGTGT TTTTTTTCAC TGACTGTTTA 
GGTGAGAAGG AATGGGACTT GCTAATGTTT TTAGGAGAGG CTGCCATTGA AAGATGCTAC 
TTTGTTCTCA GTTCCCAAGC CAGGGAGAGT GAAGAGGCTC AAATTTTTCA GAGGATACTG 
AACTTGAAGC CAGCACAGCT ACTGTTTTGG GAGAGGGGAG ATGCTGGGGA TAGAAGGAAG 
AACATGGAGG GCCTTCAAGC TGCCCTCCAG GAAGTGATGT TCTCTTCTTG CCTCAGATGT 
GTGTCTGTGG AGGATATGGC CGCCCTGGCC AGGGAGCTGG GGATTCAGGT AGATGAAGAC 
TTTGAAAACA CTCAGAGAAT TCAAGTTTCC TCTGGAGAAA ACATGGCTGG GACAGCTGAA 
GGTGAGGGTC AGCAAAGACA CAGTCAGCTA AAAAGCTCAT CTAAAAGCCA GGCTCTAATG 
CCAATTCAAG AGCCTGGGAC TCAATGTGAG CTCAGCCAGA ATCTTCAGAA TCTCTATGGT 
ACCCCAGTAT TCAGGCCTGT TCTAGAGAAC TCCTGGCTCT TTCCAACCAG AATTGGAGGT 
AACTTTAACC ATGTTTCCTT GAAAGCCTCC TGGGTTATGG GCCGCCCCTT TGGGTCAGAG 
CAGAGGCCTA AGTGGTTCCA TCCTTTGCCT TTTCAGAATG CAGGGGCCCA GGGCCGAGGT 
AAAAGTTTTG GTATTCAATC CTTCCATCCC CAGATATTTT ATTCAGGTGA AAGATTCATG 
AAATTTTCCA GAGTTGCTCG GGGATGTCAC TCGAATGGAA CATTTGGGAG ACTGCCAAGA 
CCCATTTGTC AGCATGTACA GGCCTGCCCT GAGAGACCAC AAATGATGGG AACTCTTGAA 
AGGTCTAGGG CAGTAGCCTC CAAGATAGGT CACTCCTATT CCCTGGATTC ACAGCCAGCA 
AGAGCAGTAG GGAAGCCATG GCCTCAGCAA GCTTGCACCA GGGTAACAGA GTTAACTGAA 
GCAACTGGAA AACTGATAAG AACATCCCAT ATTGGAAAGC CTCACCCTCA GTCCTTTCAA 
CCAGCAGCAG CCACACAAAA ACTAAGACCT GCTTCTCAGC AAGGAGTCCA GATGAAGACA 
CAAGGTGGGG CTTCAAATCC AGCTCTCCAA ATAGGGTCCC ATCCCATGTG CAAGAGCTCT 
CAGTTCAAAT CCGATCAGTC CAACCCATCC ACAGTCAAAC ACTCCCAGCC TAAACCCTTC 
CATTCTGTGC CCTCTCAACC TAAATCCTCT CAGACAAAAT CCTGTCAGTC CCAGCCCTCC 
CAAACTAAAC CTTCTCCATG CAAATCTACT CAGCCTAAGC CAAGCCAGCC CTGGCCTCCC 
CAGTCTAAGC CTTCTCAGCC CAGACCCCCT CAACCTAAGT CATCCTCAAC CAATCCTTCA 
CAAGCTAAGG CACACCACTC AAAAGCAGGG CAGAAGAGGG GAGGGAAGCA TTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CARD6 ( XM_017009990.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_016865479.1 Homo sapiens caspase recruitment domain family member 6 (CARD6), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu96166
Clone ID Related Accession (Same CDS sequence)	XM_017009990.2 , XM_017009990.1
Accession Version	XM_017009990.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2232bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	caspase recruitment domain-containing protein 6 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000005.10) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_017009990.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGATAGAA GCAGAAAGGT TCTGCCAGAT TTTGTTAAAC AATTCTCCTT AGATCGAGGA 
TGTAAGTGGA CCCCTGAGAG TCCAGGAGAC TTAGCCTGGA ATTTCCTGAT GAAAGTTCAA 
GCACGAGATG TGACGGCTAG GGATTCAATC CTCAGTCACA AGGTTCTGGA TGAAGATAGC 
AAGGAGGATT TGCTGGCTGG AGTGGAGAAT TTGGAAATTC GAGACATACA AACCATTAAT 
CCCCTTGACG TGCTTTGTGC CACCATGCTG TGTTCAGATA GCTCTTTGCA ACGCCAAGTC 
ATGTCAAACA TGTATCAGTG CCAGTTTGCT CTTCCCCTGC TACTGCCAGA TGCAGAAAAC 
AACAAAAGCA TCTTAATGCT GGGGGCCATG AAAGACATTG TGAAGAAGCA GTCAACACAG 
TTTTCAGGGG GGCCTACAGA GGATACAGAA AAGTTTCTGA CTCTCATGAA GATGCCTGTC 
ATCTCTTTTG TGCGTCTAGG ATACTGTAGC TTCTCTAAGT CCAGAATCCT CAACACACTT 
CTCAGCCCTG CCCAGTTGAA ATTACACAAA ATCTTTCTTC ATCAAGATTT GCCTCTTTTG 
GTGCTTCCCC GGCAAATCTC TGATGGCCTG GTTGAGATAA CATGGTGTTT TCCTGATAGC 
GATGATAGAA AGGAAAACCC CTTTTTCCAA AAGCCTGTTG CTCTGGCTAA TCTCCGTGGA 
AATCTAGAAA GCTTTTGGAC TCAGTTTGGT TTTTTGATGG AAGTTTCTTC AGCTGTGTTT 
TTTTTCACTG ACTGTTTAGG TGAGAAGGAA TGGGACTTGC TAATGTTTTT AGGAGAGGCT 
GCCATTGAAA GATGCTACTT TGTTCTCAGT TCCCAAGCCA GGGAGAGTGA AGAGGCTCAA 
ATTTTTCAGA GGATACTGAA CTTGAAGCCA GCACAGCTAC TGTTTTGGGA GAGGGGAGAT 
GCTGGGGATA GAAGGAAGAA CATGGAGGGC CTTCAAGCTG CCCTCCAGGA AGTGATGTTC 
TCTTCTTGCC TCAGATGTGT GTCTGTGGAG GATATGGCCG CCCTGGCCAG GGAGCTGGGG 
ATTCAGGTAG ATGAAGACTT TGAAAACACT CAGAGAATTC AAGTTTCCTC TGGAGAAAAC 
ATGGCTGGGA CAGCTGAAGG TGAGGGTCAG CAAAGACACA GTCAGCTAAA AAGCTCATCT 
AAAAGCCAGG CTCTAATGCC AATTCAAGAG CCTGGGACTC AATGTGAGCT CAGCCAGAAT 
CTTCAGAATC TCTATGGTAC CCCAGTATTC AGGCCTGTTC TAGAGAACTC CTGGCTCTTT 
CCAACCAGAA TTGGAGGTAA CTTTAACCAT GTTTCCTTGA AAGCCTCCTG GGTTATGGGC 
CGCCCCTTTG GGTCAGAGCA GAGGCCTAAG TGGTTCCATC CTTTGCCTTT TCAGAATGCA 
GGGGCCCAGG GCCGAGGTAA AAGTTTTGGT ATTCAATCCT TCCATCCCCA GATATTTTAT 
TCAGGTGAAA GATTCATGAA ATTTTCCAGA GTTGCTCGGG GATGTCACTC GAATGGAACA 
TTTGGGAGAC TGCCAAGACC CATTTGTCAG CATGTACAGG CCTGCCCTGA GAGACCACAA 
ATGATGGGAA CTCTTGAAAG GTCTAGGGCA GTAGCCTCCA AGATAGGTCA CTCCTATTCC 
CTGGATTCAC AGCCAGCAAG AGCAGTAGGG AAGCCATGGC CTCAGCAAGC TTGCACCAGG 
GTAACAGAGT TAACTGAAGC AACTGGAAAA CTGATAAGAA CATCCCATAT TGGAAAGCCT 
CACCCTCAGT CCTTTCAACC AGCAGCAGCC ACACAAAAAC TAAGACCTGC TTCTCAGCAA 
GGAGTCCAGA TGAAGACACA AGGTGGGGCT TCAAATCCAG CTCTCCAAAT AGGGTCCCAT 
CCCATGTGCA AGAGCTCTCA GTTCAAATCC GATCAGTCCA ACCCATCCAC AGTCAAACAC 
TCCCAGCCTA AACCCTTCCA TTCTGTGCCC TCTCAACCTA AATCCTCTCA GACAAAATCC 
TGTCAGTCCC AGCCCTCCCA AACTAAACCT TCTCCATGCA AATCTACTCA GCCTAAGCCA 
AGCCAGCCCT GGCCTCCCCA GTCTAAGCCT TCTCAGCCCA GACCCCCTCA ACCTAAGTCA 
TCCTCAACCA ATCCTTCACA AGCTAAGGCA CACCACTCAA AAGCAGGGCA GAAGAGGGGA 
GGGAAGCATT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016865479.1
CDS	735..2966
Translation	MDRSRKVLPDFVKQFSLDRGCKWTPESPGDLAWNFLMKVQARDVTARDSILSHKVLDEDSKEDLLAGVENLEIRDIQTINPLDVLCATMLCSDSSLQRQVMSNMYQCQFALPLLLPDAENNKSILMLGAMKDIVKKQSTQFSGGPTEDTEKFLTLMKMPVISFVRLGYCSFSKSRILNTLLSPAQLKLHKIFLHQDLPLLVLPRQISDGLVEITWCFPDSDDRKENPFFQKPVALANLRGNLESFWTQFGFLMEVSSAVFFFTDCLGEKEWDLLMFLGEAAIERCYFVLSSQARESEEAQIFQRILNLKPAQLLFWERGDAGDRRKNMEGLQAALQEVMFSSCLRCVSVEDMAALARELGIQVDEDFENTQRIQVSSGENMAGTAEGEGQQRHSQLKSSSKSQALMPIQEPGTQCELSQNLQNLYGTPVFRPVLENSWLFPTRIGGNFNHVSLKASWVMGRPFGSEQRPKWFHPLPFQNAGAQGRGKSFGIQSFHPQIFYSGERFMKFSRVARGCHSNGTFGRLPRPICQHVQACPERPQMMGTLERSRAVASKIGHSYSLDSQPARAVGKPWPQQACTRVTELTEATGKLIRTSHIGKPHPQSFQPAAATQKLRPASQQGVQMKTQGGASNPALQIGSHPMCKSSQFKSDQSNPSTVKHSQPKPFHSVPSQPKSSQTKSCQSQPSQTKPSPCKSTQPKPSQPWPPQSKPSQPRPPQPKSSSTNPSQAKAHHSKAGQKRGGKH

Target ORF information:

RefSeq Version	XM_017009990.2
Organism	Homo sapiens(human)
Definition	Homo sapiens caspase recruitment domain family member 6 (CARD6), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017009990.2

ORF Insert Sequence:

ATGGATAGAA GCAGAAAGGT TCTGCCAGAT TTTGTTAAAC AATTCTCCTT AGATCGAGGA 
TGTAAGTGGA CCCCTGAGAG TCCAGGAGAC TTAGCCTGGA ATTTCCTGAT GAAAGTTCAA 
GCACGAGATG TGACGGCTAG GGATTCAATC CTCAGTCACA AGGTTCTGGA TGAAGATAGC 
AAGGAGGATT TGCTGGCTGG AGTGGAGAAT TTGGAAATTC GAGACATACA AACCATTAAT 
CCCCTTGACG TGCTTTGTGC CACCATGCTG TGTTCAGATA GCTCTTTGCA ACGCCAAGTC 
ATGTCAAACA TGTATCAGTG CCAGTTTGCT CTTCCCCTGC TACTGCCAGA TGCAGAAAAC 
AACAAAAGCA TCTTAATGCT GGGGGCCATG AAAGACATTG TGAAGAAGCA GTCAACACAG 
TTTTCAGGGG GGCCTACAGA GGATACAGAA AAGTTTCTGA CTCTCATGAA GATGCCTGTC 
ATCTCTTTTG TGCGTCTAGG ATACTGTAGC TTCTCTAAGT CCAGAATCCT CAACACACTT 
CTCAGCCCTG CCCAGTTGAA ATTACACAAA ATCTTTCTTC ATCAAGATTT GCCTCTTTTG 
GTGCTTCCCC GGCAAATCTC TGATGGCCTG GTTGAGATAA CATGGTGTTT TCCTGATAGC 
GATGATAGAA AGGAAAACCC CTTTTTCCAA AAGCCTGTTG CTCTGGCTAA TCTCCGTGGA 
AATCTAGAAA GCTTTTGGAC TCAGTTTGGT TTTTTGATGG AAGTTTCTTC AGCTGTGTTT 
TTTTTCACTG ACTGTTTAGG TGAGAAGGAA TGGGACTTGC TAATGTTTTT AGGAGAGGCT 
GCCATTGAAA GATGCTACTT TGTTCTCAGT TCCCAAGCCA GGGAGAGTGA AGAGGCTCAA 
ATTTTTCAGA GGATACTGAA CTTGAAGCCA GCACAGCTAC TGTTTTGGGA GAGGGGAGAT 
GCTGGGGATA GAAGGAAGAA CATGGAGGGC CTTCAAGCTG CCCTCCAGGA AGTGATGTTC 
TCTTCTTGCC TCAGATGTGT GTCTGTGGAG GATATGGCCG CCCTGGCCAG GGAGCTGGGG 
ATTCAGGTAG ATGAAGACTT TGAAAACACT CAGAGAATTC AAGTTTCCTC TGGAGAAAAC 
ATGGCTGGGA CAGCTGAAGG TGAGGGTCAG CAAAGACACA GTCAGCTAAA AAGCTCATCT 
AAAAGCCAGG CTCTAATGCC AATTCAAGAG CCTGGGACTC AATGTGAGCT CAGCCAGAAT 
CTTCAGAATC TCTATGGTAC CCCAGTATTC AGGCCTGTTC TAGAGAACTC CTGGCTCTTT 
CCAACCAGAA TTGGAGGTAA CTTTAACCAT GTTTCCTTGA AAGCCTCCTG GGTTATGGGC 
CGCCCCTTTG GGTCAGAGCA GAGGCCTAAG TGGTTCCATC CTTTGCCTTT TCAGAATGCA 
GGGGCCCAGG GCCGAGGTAA AAGTTTTGGT ATTCAATCCT TCCATCCCCA GATATTTTAT 
TCAGGTGAAA GATTCATGAA ATTTTCCAGA GTTGCTCGGG GATGTCACTC GAATGGAACA 
TTTGGGAGAC TGCCAAGACC CATTTGTCAG CATGTACAGG CCTGCCCTGA GAGACCACAA 
ATGATGGGAA CTCTTGAAAG GTCTAGGGCA GTAGCCTCCA AGATAGGTCA CTCCTATTCC 
CTGGATTCAC AGCCAGCAAG AGCAGTAGGG AAGCCATGGC CTCAGCAAGC TTGCACCAGG 
GTAACAGAGT TAACTGAAGC AACTGGAAAA CTGATAAGAA CATCCCATAT TGGAAAGCCT 
CACCCTCAGT CCTTTCAACC AGCAGCAGCC ACACAAAAAC TAAGACCTGC TTCTCAGCAA 
GGAGTCCAGA TGAAGACACA AGGTGGGGCT TCAAATCCAG CTCTCCAAAT AGGGTCCCAT 
CCCATGTGCA AGAGCTCTCA GTTCAAATCC GATCAGTCCA ACCCATCCAC AGTCAAACAC 
TCCCAGCCTA AACCCTTCCA TTCTGTGCCC TCTCAACCTA AATCCTCTCA GACAAAATCC 
TGTCAGTCCC AGCCCTCCCA AACTAAACCT TCTCCATGCA AATCTACTCA GCCTAAGCCA 
AGCCAGCCCT GGCCTCCCCA GTCTAAGCCT TCTCAGCCCA GACCCCCTCA ACCTAAGTCA 
TCCTCAACCA ATCCTTCACA AGCTAAGGCA CACCACTCAA AAGCAGGGCA GAAGAGGGGA 
GGGAAGCATT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CARD6 ( XM_017009990.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016865479.1 Homo sapiens caspase recruitment domain family member 6 (CARD6), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu96166
Clone ID Related Accession (Same CDS sequence)	XM_017009990.2 , XM_017009990.1
Accession Version	XM_017009990.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2232bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	caspase recruitment domain-containing protein 6 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000005.10) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGATAGAA GCAGAAAGGT TCTGCCAGAT TTTGTTAAAC AATTCTCCTT AGATCGAGGA 
TGTAAGTGGA CCCCTGAGAG TCCAGGAGAC TTAGCCTGGA ATTTCCTGAT GAAAGTTCAA 
GCACGAGATG TGACGGCTAG GGATTCAATC CTCAGTCACA AGGTTCTGGA TGAAGATAGC 
AAGGAGGATT TGCTGGCTGG AGTGGAGAAT TTGGAAATTC GAGACATACA AACCATTAAT 
CCCCTTGACG TGCTTTGTGC CACCATGCTG TGTTCAGATA GCTCTTTGCA ACGCCAAGTC 
ATGTCAAACA TGTATCAGTG CCAGTTTGCT CTTCCCCTGC TACTGCCAGA TGCAGAAAAC 
AACAAAAGCA TCTTAATGCT GGGGGCCATG AAAGACATTG TGAAGAAGCA GTCAACACAG 
TTTTCAGGGG GGCCTACAGA GGATACAGAA AAGTTTCTGA CTCTCATGAA GATGCCTGTC 
ATCTCTTTTG TGCGTCTAGG ATACTGTAGC TTCTCTAAGT CCAGAATCCT CAACACACTT 
CTCAGCCCTG CCCAGTTGAA ATTACACAAA ATCTTTCTTC ATCAAGATTT GCCTCTTTTG 
GTGCTTCCCC GGCAAATCTC TGATGGCCTG GTTGAGATAA CATGGTGTTT TCCTGATAGC 
GATGATAGAA AGGAAAACCC CTTTTTCCAA AAGCCTGTTG CTCTGGCTAA TCTCCGTGGA 
AATCTAGAAA GCTTTTGGAC TCAGTTTGGT TTTTTGATGG AAGTTTCTTC AGCTGTGTTT 
TTTTTCACTG ACTGTTTAGG TGAGAAGGAA TGGGACTTGC TAATGTTTTT AGGAGAGGCT 
GCCATTGAAA GATGCTACTT TGTTCTCAGT TCCCAAGCCA GGGAGAGTGA AGAGGCTCAA 
ATTTTTCAGA GGATACTGAA CTTGAAGCCA GCACAGCTAC TGTTTTGGGA GAGGGGAGAT 
GCTGGGGATA GAAGGAAGAA CATGGAGGGC CTTCAAGCTG CCCTCCAGGA AGTGATGTTC 
TCTTCTTGCC TCAGATGTGT GTCTGTGGAG GATATGGCCG CCCTGGCCAG GGAGCTGGGG 
ATTCAGGTAG ATGAAGACTT TGAAAACACT CAGAGAATTC AAGTTTCCTC TGGAGAAAAC 
ATGGCTGGGA CAGCTGAAGG TGAGGGTCAG CAAAGACACA GTCAGCTAAA AAGCTCATCT 
AAAAGCCAGG CTCTAATGCC AATTCAAGAG CCTGGGACTC AATGTGAGCT CAGCCAGAAT 
CTTCAGAATC TCTATGGTAC CCCAGTATTC AGGCCTGTTC TAGAGAACTC CTGGCTCTTT 
CCAACCAGAA TTGGAGGTAA CTTTAACCAT GTTTCCTTGA AAGCCTCCTG GGTTATGGGC 
CGCCCCTTTG GGTCAGAGCA GAGGCCTAAG TGGTTCCATC CTTTGCCTTT TCAGAATGCA 
GGGGCCCAGG GCCGAGGTAA AAGTTTTGGT ATTCAATCCT TCCATCCCCA GATATTTTAT 
TCAGGTGAAA GATTCATGAA ATTTTCCAGA GTTGCTCGGG GATGTCACTC GAATGGAACA 
TTTGGGAGAC TGCCAAGACC CATTTGTCAG CATGTACAGG CCTGCCCTGA GAGACCACAA 
ATGATGGGAA CTCTTGAAAG GTCTAGGGCA GTAGCCTCCA AGATAGGTCA CTCCTATTCC 
CTGGATTCAC AGCCAGCAAG AGCAGTAGGG AAGCCATGGC CTCAGCAAGC TTGCACCAGG 
GTAACAGAGT TAACTGAAGC AACTGGAAAA CTGATAAGAA CATCCCATAT TGGAAAGCCT 
CACCCTCAGT CCTTTCAACC AGCAGCAGCC ACACAAAAAC TAAGACCTGC TTCTCAGCAA 
GGAGTCCAGA TGAAGACACA AGGTGGGGCT TCAAATCCAG CTCTCCAAAT AGGGTCCCAT 
CCCATGTGCA AGAGCTCTCA GTTCAAATCC GATCAGTCCA ACCCATCCAC AGTCAAACAC 
TCCCAGCCTA AACCCTTCCA TTCTGTGCCC TCTCAACCTA AATCCTCTCA GACAAAATCC 
TGTCAGTCCC AGCCCTCCCA AACTAAACCT TCTCCATGCA AATCTACTCA GCCTAAGCCA 
AGCCAGCCCT GGCCTCCCCA GTCTAAGCCT TCTCAGCCCA GACCCCCTCA ACCTAAGTCA 
TCCTCAACCA ATCCTTCACA AGCTAAGGCA CACCACTCAA AAGCAGGGCA GAAGAGGGGA 
GGGAAGCATT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016865479.1
CDS	1192..3423
Translation	MDRSRKVLPDFVKQFSLDRGCKWTPESPGDLAWNFLMKVQARDVTARDSILSHKVLDEDSKEDLLAGVENLEIRDIQTINPLDVLCATMLCSDSSLQRQVMSNMYQCQFALPLLLPDAENNKSILMLGAMKDIVKKQSTQFSGGPTEDTEKFLTLMKMPVISFVRLGYCSFSKSRILNTLLSPAQLKLHKIFLHQDLPLLVLPRQISDGLVEITWCFPDSDDRKENPFFQKPVALANLRGNLESFWTQFGFLMEVSSAVFFFTDCLGEKEWDLLMFLGEAAIERCYFVLSSQARESEEAQIFQRILNLKPAQLLFWERGDAGDRRKNMEGLQAALQEVMFSSCLRCVSVEDMAALARELGIQVDEDFENTQRIQVSSGENMAGTAEGEGQQRHSQLKSSSKSQALMPIQEPGTQCELSQNLQNLYGTPVFRPVLENSWLFPTRIGGNFNHVSLKASWVMGRPFGSEQRPKWFHPLPFQNAGAQGRGKSFGIQSFHPQIFYSGERFMKFSRVARGCHSNGTFGRLPRPICQHVQACPERPQMMGTLERSRAVASKIGHSYSLDSQPARAVGKPWPQQACTRVTELTEATGKLIRTSHIGKPHPQSFQPAAATQKLRPASQQGVQMKTQGGASNPALQIGSHPMCKSSQFKSDQSNPSTVKHSQPKPFHSVPSQPKSSQTKSCQSQPSQTKPSPCKSTQPKPSQPWPPQSKPSQPRPPQPKSSSTNPSQAKAHHSKAGQKRGGKH

Target ORF information:

RefSeq Version	XM_017009990.1
Organism	Homo sapiens(human)
Definition	Homo sapiens caspase recruitment domain family member 6 (CARD6), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017009990.1

ORF Insert Sequence:

ATGGATAGAA GCAGAAAGGT TCTGCCAGAT TTTGTTAAAC AATTCTCCTT AGATCGAGGA 
TGTAAGTGGA CCCCTGAGAG TCCAGGAGAC TTAGCCTGGA ATTTCCTGAT GAAAGTTCAA 
GCACGAGATG TGACGGCTAG GGATTCAATC CTCAGTCACA AGGTTCTGGA TGAAGATAGC 
AAGGAGGATT TGCTGGCTGG AGTGGAGAAT TTGGAAATTC GAGACATACA AACCATTAAT 
CCCCTTGACG TGCTTTGTGC CACCATGCTG TGTTCAGATA GCTCTTTGCA ACGCCAAGTC 
ATGTCAAACA TGTATCAGTG CCAGTTTGCT CTTCCCCTGC TACTGCCAGA TGCAGAAAAC 
AACAAAAGCA TCTTAATGCT GGGGGCCATG AAAGACATTG TGAAGAAGCA GTCAACACAG 
TTTTCAGGGG GGCCTACAGA GGATACAGAA AAGTTTCTGA CTCTCATGAA GATGCCTGTC 
ATCTCTTTTG TGCGTCTAGG ATACTGTAGC TTCTCTAAGT CCAGAATCCT CAACACACTT 
CTCAGCCCTG CCCAGTTGAA ATTACACAAA ATCTTTCTTC ATCAAGATTT GCCTCTTTTG 
GTGCTTCCCC GGCAAATCTC TGATGGCCTG GTTGAGATAA CATGGTGTTT TCCTGATAGC 
GATGATAGAA AGGAAAACCC CTTTTTCCAA AAGCCTGTTG CTCTGGCTAA TCTCCGTGGA 
AATCTAGAAA GCTTTTGGAC TCAGTTTGGT TTTTTGATGG AAGTTTCTTC AGCTGTGTTT 
TTTTTCACTG ACTGTTTAGG TGAGAAGGAA TGGGACTTGC TAATGTTTTT AGGAGAGGCT 
GCCATTGAAA GATGCTACTT TGTTCTCAGT TCCCAAGCCA GGGAGAGTGA AGAGGCTCAA 
ATTTTTCAGA GGATACTGAA CTTGAAGCCA GCACAGCTAC TGTTTTGGGA GAGGGGAGAT 
GCTGGGGATA GAAGGAAGAA CATGGAGGGC CTTCAAGCTG CCCTCCAGGA AGTGATGTTC 
TCTTCTTGCC TCAGATGTGT GTCTGTGGAG GATATGGCCG CCCTGGCCAG GGAGCTGGGG 
ATTCAGGTAG ATGAAGACTT TGAAAACACT CAGAGAATTC AAGTTTCCTC TGGAGAAAAC 
ATGGCTGGGA CAGCTGAAGG TGAGGGTCAG CAAAGACACA GTCAGCTAAA AAGCTCATCT 
AAAAGCCAGG CTCTAATGCC AATTCAAGAG CCTGGGACTC AATGTGAGCT CAGCCAGAAT 
CTTCAGAATC TCTATGGTAC CCCAGTATTC AGGCCTGTTC TAGAGAACTC CTGGCTCTTT 
CCAACCAGAA TTGGAGGTAA CTTTAACCAT GTTTCCTTGA AAGCCTCCTG GGTTATGGGC 
CGCCCCTTTG GGTCAGAGCA GAGGCCTAAG TGGTTCCATC CTTTGCCTTT TCAGAATGCA 
GGGGCCCAGG GCCGAGGTAA AAGTTTTGGT ATTCAATCCT TCCATCCCCA GATATTTTAT 
TCAGGTGAAA GATTCATGAA ATTTTCCAGA GTTGCTCGGG GATGTCACTC GAATGGAACA 
TTTGGGAGAC TGCCAAGACC CATTTGTCAG CATGTACAGG CCTGCCCTGA GAGACCACAA 
ATGATGGGAA CTCTTGAAAG GTCTAGGGCA GTAGCCTCCA AGATAGGTCA CTCCTATTCC 
CTGGATTCAC AGCCAGCAAG AGCAGTAGGG AAGCCATGGC CTCAGCAAGC TTGCACCAGG 
GTAACAGAGT TAACTGAAGC AACTGGAAAA CTGATAAGAA CATCCCATAT TGGAAAGCCT 
CACCCTCAGT CCTTTCAACC AGCAGCAGCC ACACAAAAAC TAAGACCTGC TTCTCAGCAA 
GGAGTCCAGA TGAAGACACA AGGTGGGGCT TCAAATCCAG CTCTCCAAAT AGGGTCCCAT 
CCCATGTGCA AGAGCTCTCA GTTCAAATCC GATCAGTCCA ACCCATCCAC AGTCAAACAC 
TCCCAGCCTA AACCCTTCCA TTCTGTGCCC TCTCAACCTA AATCCTCTCA GACAAAATCC 
TGTCAGTCCC AGCCCTCCCA AACTAAACCT TCTCCATGCA AATCTACTCA GCCTAAGCCA 
AGCCAGCCCT GGCCTCCCCA GTCTAAGCCT TCTCAGCCCA GACCCCCTCA ACCTAAGTCA 
TCCTCAACCA ATCCTTCACA AGCTAAGGCA CACCACTCAA AAGCAGGGCA GAAGAGGGGA 
GGGAAGCATT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CARD6 ( XM_017009989.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016865478.1 Homo sapiens caspase recruitment domain family member 6 (CARD6), transcript variant X1, mRNA.

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CloneID	OHu96165
Clone ID Related Accession (Same CDS sequence)	XM_017009989.1
Accession Version	XM_017009989.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2556bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	caspase recruitment domain-containing protein 6 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000005.10) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCTACCG AGAGTACTCC CTCAGAGATC ATAGAAAGAG AAAGAAAAAA GTTGCTTGAA 
ATCCTTCAAC ATGATCCTGA TTCTATCTTA GACACGTTAA CTTCTCGGAG GCTGATTTCT 
GAGGAAGAGT ATGAGACTCT GGAGAATGTT ACAGATCTCC TGAAGAAAAG TCGGAAGCTG 
TTAATTTTGG TACAGAAAAA GGGAGAGGCG ACCTGTCAGC ATTTTCTCAA GTGTTTATTT 
AGTACTTTTC CACAGTCAGC TGCCATTTGC GGCTTAAGGC ATGAAAGAAA AAAGGTGTTT 
AAAGATGTCC TGTTATGTTT GAACATGGAT AGAAGCAGAA AGGTTCTGCC AGATTTTGTT 
AAACAATTCT CCTTAGATCG AGGATGTAAG TGGACCCCTG AGAGTCCAGG AGACTTAGCC 
TGGAATTTCC TGATGAAAGT TCAAGCACGA GATGTGACGG CTAGGGATTC AATCCTCAGT 
CACAAGGTTC TGGATGAAGA TAGCAAGGAG GATTTGCTGG CTGGAGTGGA GAATTTGGAA 
ATTCGAGACA TACAAACCAT TAATCCCCTT GACGTGCTTT GTGCCACCAT GCTGTGTTCA 
GATAGCTCTT TGCAACGCCA AGTCATGTCA AACATGTATC AGTGCCAGTT TGCTCTTCCC 
CTGCTACTGC CAGATGCAGA AAACAACAAA AGCATCTTAA TGCTGGGGGC CATGAAAGAC 
ATTGTGAAGA AGCAGTCAAC ACAGTTTTCA GGGGGGCCTA CAGAGGATAC AGAAAAGTTT 
CTGACTCTCA TGAAGATGCC TGTCATCTCT TTTGTGCGTC TAGGATACTG TAGCTTCTCT 
AAGTCCAGAA TCCTCAACAC ACTTCTCAGC CCTGCCCAGT TGAAATTACA CAAAATCTTT 
CTTCATCAAG ATTTGCCTCT TTTGGTGCTT CCCCGGCAAA TCTCTGATGG CCTGGTTGAG 
ATAACATGGT GTTTTCCTGA TAGCGATGAT AGAAAGGAAA ACCCCTTTTT CCAAAAGCCT 
GTTGCTCTGG CTAATCTCCG TGGAAATCTA GAAAGCTTTT GGACTCAGTT TGGTTTTTTG 
ATGGAAGTTT CTTCAGCTGT GTTTTTTTTC ACTGACTGTT TAGGTGAGAA GGAATGGGAC 
TTGCTAATGT TTTTAGGAGA GGCTGCCATT GAAAGATGCT ACTTTGTTCT CAGTTCCCAA 
GCCAGGGAGA GTGAAGAGGC TCAAATTTTT CAGAGGATAC TGAACTTGAA GCCAGCACAG 
CTACTGTTTT GGGAGAGGGG AGATGCTGGG GATAGAAGGA AGAACATGGA GGGCCTTCAA 
GCTGCCCTCC AGGAAGTGAT GTTCTCTTCT TGCCTCAGAT GTGTGTCTGT GGAGGATATG 
GCCGCCCTGG CCAGGGAGCT GGGGATTCAG GTAGATGAAG ACTTTGAAAA CACTCAGAGA 
ATTCAAGTTT CCTCTGGAGA AAACATGGCT GGGACAGCTG AAGGTGAGGG TCAGCAAAGA 
CACAGTCAGC TAAAAAGCTC ATCTAAAAGC CAGGCTCTAA TGCCAATTCA AGAGCCTGGG 
ACTCAATGTG AGCTCAGCCA GAATCTTCAG AATCTCTATG GTACCCCAGT ATTCAGGCCT 
GTTCTAGAGA ACTCCTGGCT CTTTCCAACC AGAATTGGAG GTAACTTTAA CCATGTTTCC 
TTGAAAGCCT CCTGGGTTAT GGGCCGCCCC TTTGGGTCAG AGCAGAGGCC TAAGTGGTTC 
CATCCTTTGC CTTTTCAGAA TGCAGGGGCC CAGGGCCGAG GTAAAAGTTT TGGTATTCAA 
TCCTTCCATC CCCAGATATT TTATTCAGGT GAAAGATTCA TGAAATTTTC CAGAGTTGCT 
CGGGGATGTC ACTCGAATGG AACATTTGGG AGACTGCCAA GACCCATTTG TCAGCATGTA 
CAGGCCTGCC CTGAGAGACC ACAAATGATG GGAACTCTTG AAAGGTCTAG GGCAGTAGCC 
TCCAAGATAG GTCACTCCTA TTCCCTGGAT TCACAGCCAG CAAGAGCAGT AGGGAAGCCA 
TGGCCTCAGC AAGCTTGCAC CAGGGTAACA GAGTTAACTG AAGCAACTGG AAAACTGATA 
AGAACATCCC ATATTGGAAA GCCTCACCCT CAGTCCTTTC AACCAGCAGC AGCCACACAA 
AAACTAAGAC CTGCTTCTCA GCAAGGAGTC CAGATGAAGA CACAAGGTGG GGCTTCAAAT 
CCAGCTCTCC AAATAGGGTC CCATCCCATG TGCAAGAGCT CTCAGTTCAA ATCCGATCAG 
TCCAACCCAT CCACAGTCAA ACACTCCCAG CCTAAACCCT TCCATTCTGT GCCCTCTCAA 
CCTAAATCCT CTCAGACAAA ATCCTGTCAG TCCCAGCCCT CCCAAACTAA ACCTTCTCCA 
TGCAAATCTA CTCAGCCTAA GCCAAGCCAG CCCTGGCCTC CCCAGTCTAA GCCTTCTCAG 
CCCAGACCCC CTCAACCTAA GTCATCCTCA ACCAATCCTT CACAAGCTAA GGCACACCAC 
TCAAAAGCAG GGCAGAAGAG GGGAGGGAAG CATTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016865478.1
CDS	187..2742
Translation	MATESTPSEIIERERKKLLEILQHDPDSILDTLTSRRLISEEEYETLENVTDLLKKSRKLLILVQKKGEATCQHFLKCLFSTFPQSAAICGLRHERKKVFKDVLLCLNMDRSRKVLPDFVKQFSLDRGCKWTPESPGDLAWNFLMKVQARDVTARDSILSHKVLDEDSKEDLLAGVENLEIRDIQTINPLDVLCATMLCSDSSLQRQVMSNMYQCQFALPLLLPDAENNKSILMLGAMKDIVKKQSTQFSGGPTEDTEKFLTLMKMPVISFVRLGYCSFSKSRILNTLLSPAQLKLHKIFLHQDLPLLVLPRQISDGLVEITWCFPDSDDRKENPFFQKPVALANLRGNLESFWTQFGFLMEVSSAVFFFTDCLGEKEWDLLMFLGEAAIERCYFVLSSQARESEEAQIFQRILNLKPAQLLFWERGDAGDRRKNMEGLQAALQEVMFSSCLRCVSVEDMAALARELGIQVDEDFENTQRIQVSSGENMAGTAEGEGQQRHSQLKSSSKSQALMPIQEPGTQCELSQNLQNLYGTPVFRPVLENSWLFPTRIGGNFNHVSLKASWVMGRPFGSEQRPKWFHPLPFQNAGAQGRGKSFGIQSFHPQIFYSGERFMKFSRVARGCHSNGTFGRLPRPICQHVQACPERPQMMGTLERSRAVASKIGHSYSLDSQPARAVGKPWPQQACTRVTELTEATGKLIRTSHIGKPHPQSFQPAAATQKLRPASQQGVQMKTQGGASNPALQIGSHPMCKSSQFKSDQSNPSTVKHSQPKPFHSVPSQPKSSQTKSCQSQPSQTKPSPCKSTQPKPSQPWPPQSKPSQPRPPQPKSSSTNPSQAKAHHSKAGQKRGGKH

Target ORF information:

RefSeq Version	XM_017009989.1
Organism	Homo sapiens(human)
Definition	Homo sapiens caspase recruitment domain family member 6 (CARD6), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017009989.1

ORF Insert Sequence:

ATGGCTACCG AGAGTACTCC CTCAGAGATC ATAGAAAGAG AAAGAAAAAA GTTGCTTGAA 
ATCCTTCAAC ATGATCCTGA TTCTATCTTA GACACGTTAA CTTCTCGGAG GCTGATTTCT 
GAGGAAGAGT ATGAGACTCT GGAGAATGTT ACAGATCTCC TGAAGAAAAG TCGGAAGCTG 
TTAATTTTGG TACAGAAAAA GGGAGAGGCG ACCTGTCAGC ATTTTCTCAA GTGTTTATTT 
AGTACTTTTC CACAGTCAGC TGCCATTTGC GGCTTAAGGC ATGAAAGAAA AAAGGTGTTT 
AAAGATGTCC TGTTATGTTT GAACATGGAT AGAAGCAGAA AGGTTCTGCC AGATTTTGTT 
AAACAATTCT CCTTAGATCG AGGATGTAAG TGGACCCCTG AGAGTCCAGG AGACTTAGCC 
TGGAATTTCC TGATGAAAGT TCAAGCACGA GATGTGACGG CTAGGGATTC AATCCTCAGT 
CACAAGGTTC TGGATGAAGA TAGCAAGGAG GATTTGCTGG CTGGAGTGGA GAATTTGGAA 
ATTCGAGACA TACAAACCAT TAATCCCCTT GACGTGCTTT GTGCCACCAT GCTGTGTTCA 
GATAGCTCTT TGCAACGCCA AGTCATGTCA AACATGTATC AGTGCCAGTT TGCTCTTCCC 
CTGCTACTGC CAGATGCAGA AAACAACAAA AGCATCTTAA TGCTGGGGGC CATGAAAGAC 
ATTGTGAAGA AGCAGTCAAC ACAGTTTTCA GGGGGGCCTA CAGAGGATAC AGAAAAGTTT 
CTGACTCTCA TGAAGATGCC TGTCATCTCT TTTGTGCGTC TAGGATACTG TAGCTTCTCT 
AAGTCCAGAA TCCTCAACAC ACTTCTCAGC CCTGCCCAGT TGAAATTACA CAAAATCTTT 
CTTCATCAAG ATTTGCCTCT TTTGGTGCTT CCCCGGCAAA TCTCTGATGG CCTGGTTGAG 
ATAACATGGT GTTTTCCTGA TAGCGATGAT AGAAAGGAAA ACCCCTTTTT CCAAAAGCCT 
GTTGCTCTGG CTAATCTCCG TGGAAATCTA GAAAGCTTTT GGACTCAGTT TGGTTTTTTG 
ATGGAAGTTT CTTCAGCTGT GTTTTTTTTC ACTGACTGTT TAGGTGAGAA GGAATGGGAC 
TTGCTAATGT TTTTAGGAGA GGCTGCCATT GAAAGATGCT ACTTTGTTCT CAGTTCCCAA 
GCCAGGGAGA GTGAAGAGGC TCAAATTTTT CAGAGGATAC TGAACTTGAA GCCAGCACAG 
CTACTGTTTT GGGAGAGGGG AGATGCTGGG GATAGAAGGA AGAACATGGA GGGCCTTCAA 
GCTGCCCTCC AGGAAGTGAT GTTCTCTTCT TGCCTCAGAT GTGTGTCTGT GGAGGATATG 
GCCGCCCTGG CCAGGGAGCT GGGGATTCAG GTAGATGAAG ACTTTGAAAA CACTCAGAGA 
ATTCAAGTTT CCTCTGGAGA AAACATGGCT GGGACAGCTG AAGGTGAGGG TCAGCAAAGA 
CACAGTCAGC TAAAAAGCTC ATCTAAAAGC CAGGCTCTAA TGCCAATTCA AGAGCCTGGG 
ACTCAATGTG AGCTCAGCCA GAATCTTCAG AATCTCTATG GTACCCCAGT ATTCAGGCCT 
GTTCTAGAGA ACTCCTGGCT CTTTCCAACC AGAATTGGAG GTAACTTTAA CCATGTTTCC 
TTGAAAGCCT CCTGGGTTAT GGGCCGCCCC TTTGGGTCAG AGCAGAGGCC TAAGTGGTTC 
CATCCTTTGC CTTTTCAGAA TGCAGGGGCC CAGGGCCGAG GTAAAAGTTT TGGTATTCAA 
TCCTTCCATC CCCAGATATT TTATTCAGGT GAAAGATTCA TGAAATTTTC CAGAGTTGCT 
CGGGGATGTC ACTCGAATGG AACATTTGGG AGACTGCCAA GACCCATTTG TCAGCATGTA 
CAGGCCTGCC CTGAGAGACC ACAAATGATG GGAACTCTTG AAAGGTCTAG GGCAGTAGCC 
TCCAAGATAG GTCACTCCTA TTCCCTGGAT TCACAGCCAG CAAGAGCAGT AGGGAAGCCA 
TGGCCTCAGC AAGCTTGCAC CAGGGTAACA GAGTTAACTG AAGCAACTGG AAAACTGATA 
AGAACATCCC ATATTGGAAA GCCTCACCCT CAGTCCTTTC AACCAGCAGC AGCCACACAA 
AAACTAAGAC CTGCTTCTCA GCAAGGAGTC CAGATGAAGA CACAAGGTGG GGCTTCAAAT 
CCAGCTCTCC AAATAGGGTC CCATCCCATG TGCAAGAGCT CTCAGTTCAA ATCCGATCAG 
TCCAACCCAT CCACAGTCAA ACACTCCCAG CCTAAACCCT TCCATTCTGT GCCCTCTCAA 
CCTAAATCCT CTCAGACAAA ATCCTGTCAG TCCCAGCCCT CCCAAACTAA ACCTTCTCCA 
TGCAAATCTA CTCAGCCTAA GCCAAGCCAG CCCTGGCCTC CCCAGTCTAA GCCTTCTCAG 
CCCAGACCCC CTCAACCTAA GTCATCCTCA ACCAATCCTT CACAAGCTAA GGCACACCAC 
TCAAAAGCAG GGCAGAAGAG GGGAGGGAAG CATTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

NOD-like receptor signaling and inflammasome-related pathways are highlighted in psoriatic epidermis.
Scientific reports622745(2016 Mar)
Tervaniemi MH,Katayama S,Skoog T,Siitonen HA,Vuola J,Nuutila K,Sormunen R,Johnsson A,Linnarsson S,Suomela S,Kankuri E,Kere J,Elomaa O

Expression of CARD6, an NF-kappaB activator, in gastric, colorectal and oesophageal cancers.
Pathology42(1)50-3(2010 Jan)
Kim SS,Ahn CH,Kang MR,Kim YR,Kim HS,Yoo NJ,Lee SH

CARD tricks: controlling the interactions of CARD6 with RICK and microtubules.
Cell cycle (Georgetown, Tex.)5(8)797-800(2006 Apr)
Dufner A,Mak TW

Caspase recruitment domain protein 6 is a microtubule-interacting protein that positively modulates NF-kappaB activation.
Proceedings of the National Academy of Sciences of the United States of America103(4)988-93(2006 Jan)
Dufner A,Pownall S,Mak TW

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CARD6 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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