DYRK3 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	DYRK3
Entrez Gene ID	8444
Full Name	dual specificity tyrosine phosphorylation regulated kinase 3
Synonyms	DYRK5,RED,REDK,hYAK3-2
General protein information	Preferred Names dual specificity tyrosine phosphorylation regulated kinase 3 Names dual specificity tyrosine-phosphorylation-regulated kinase 3 dual specificity tyrosine-(Y)-phosphorylation regulated kinase 3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 5 protein kinase Dyrk3 regulatory erythroid kinase
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 1 Map Location: 1q32.1
Summary	This gene product belongs to the DYRK family of dual-specificity protein kinases that catalyze autophosphorylation on serine/threonine and tyrosine residues. The members of this family share structural similarity, however, differ in their substrate specificity, suggesting their involvement in different cellular functions. The encoded protein has been shown to autophosphorylate on tyrosine residue and catalyze phosphorylation of histones H3 and H2B in vitro. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008].
Disorder MIM:	603497

mRNA and Protein(s)

mRNA	Protein	Name
XM_005273315.4	XP_005273372.1	dual specificity tyrosine-phosphorylation-regulated kinase 3 isoform X1
XM_011510061.2	XP_011508363.1	dual specificity tyrosine-phosphorylation-regulated kinase 3 isoform X2
NM_003582.2	NP_003573.2	dual specificity tyrosine-phosphorylation-regulated kinase 3 isoform a
NM_001004023.2	NP_001004023.1	dual specificity tyrosine-phosphorylation-regulated kinase 3 isoform b
NM_001004023.1	NP_001004023.1	dual specificity tyrosine-phosphorylation-regulated kinase 3 isoform b
NM_003582.3	NP_003573.2	dual specificity tyrosine-phosphorylation-regulated kinase 3 isoform a

Pathways from BioSystems

Homologies

Gallus gallus (chicken)	DYRK3	XP_003642771.1
Xenopus tropicalis (tropical clawed frog)	dyrk3	NP_001008158.1
Canis lupus familiaris (dog)	DYRK3	XP_003434997.2
Bos taurus (cattle)	DYRK3	NP_001093768.1
Danio rerio (zebrafish)	zgc:172180	NP_001108400.1
Homo sapiens (human)	DYRK3	NP_003573.2
Pan troglodytes (chimpanzee)	DYRK3	XP_524527.2
	DYRK3	XP_001086117.1
Mus musculus (house mouse)	Dyrk3	NP_663483.1
Rattus norvegicus (Norway rat)	Dyrk3	NP_001019938.1

Gene Ontology
Bibliography

Related articles in PubMed

Dual specificity kinase DYRK3 couples stress granule condensation/dissolution to mTORC1 signaling.
Wippich F, Bodenmiller B, Trajkovska MG, Wanka S, Aebersold R, Pelkmans L
Cell152(4)791-805(2013 Feb)

Invasion of Cryptococcus neoformans into human brain microvascular endothelial cells is mediated through the lipid rafts-endocytic pathway via the dual specificity tyrosine phosphorylation-regulated kinase 3 (DYRK3).
Huang SH, Long M, Wu CH, Kwon-Chung KJ, Chang YC, Chi F, Lee S, Jong A
The Journal of biological chemistry286(40)34761-9(2011 Oct)

DYRK1A and DYRK3 promote cell survival through phosphorylation and activation of SIRT1.
Guo X, Williams JG, Schug TT, Li X
The Journal of biological chemistry285(17)13223-32(2010 Apr)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Study identified the dual specificity tyrosine-phosphorylation-regulated kinase 3 (DYRK3) as a protein with the ability to condense P-granule-like speckles in the cytosol and to prevent stress granule dissolution via its N-terminal domain when it is in a kinase-inactive form.
Title: Dual specificity kinase DYRK3 couples stress granule condensation/dissolution to mTORC1 signaling.

the lipid raft-dependent endocytosis process mediates C. neoformans internalization into HBMEC and the CD44 protein of the hosts, cytoskeleton, and intracellular kinase-DYRK3 are involved in this process
Title: Invasion of Cryptococcus neoformans into human brain microvascular endothelial cells is mediated through the lipid rafts-endocytic pathway via the dual specificity tyrosine phosphorylation-regulated kinase 3 (DYRK3).

DYRK1A and DYRK3 promote cell survival through phosphorylation and activation of SIRT1.
Title: DYRK1A and DYRK3 promote cell survival through phosphorylation and activation of SIRT1.

DYRK3 dual-specificity kinase attenuates erythropoiesis during anemia
Title: DYRK3 dual-specificity kinase attenuates erythropoiesis during anemia.

DYRK3, expression is strong in erythroid cells and testis, but is also detected in adult kidney and liver
Title: DYRK gene structure and erythroid-restricted features of DYRK3 gene expression.

The following DYRK3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the DYRK3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu03508	NM_001004023.2 Latest version!	Homo sapiens dual specificity tyrosine phosphorylation regulated kinase 3 (DYRK3), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$265.30 $379.00
OHu30360	NM_003582.3 Latest version!	Homo sapiens dual specificity tyrosine phosphorylation regulated kinase 3 (DYRK3), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
OHu03508	XM_005273315.4 Latest version!	Homo sapiens dual specificity tyrosine phosphorylation regulated kinase 3 (DYRK3), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$265.30 $379.00
OHu61775	XM_011510061.2 Latest version!	Homo sapiens dual specificity tyrosine phosphorylation regulated kinase 3 (DYRK3), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
View Old Accession Versions >>
OHu03508	NM_001004023.1	Homo sapiens dual specificity tyrosine phosphorylation regulated kinase 3 (DYRK3), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$265.30 $379.00
OHu30360	NM_003582.2	Homo sapiens dual specificity tyrosine phosphorylation regulated kinase 3 (DYRK3), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

DYRK3 ( NM_001004023.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001004023.1 Homo sapiens dual specificity tyrosine phosphorylation regulated kinase 3 (DYRK3), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu03508
Clone ID Related Accession (Same CDS sequence)	XM_005273315.4 , NM_001004023.2 , NM_001004023.1
Accession Version	NM_001004023.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1707bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-08
Organism	Homo sapiens(human)
Product	dual specificity tyrosine-phosphorylation-regulated kinase 3 isoform b
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AU126055.1, BC015501.1, Y12735.2 and AL591846.15. On Jun 2, 2019 this sequence version replaced NM_001004023.1. Transcript Variant: This variant (2) contains an additional segment in the coding region compared to variant 1. The resulting isoform (b), also known as the isoform RED-S, contains a shorter and distinct N-terminus compared to isoform a. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK291189.1, SRR1803611.103653.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA1968968 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on conservation, expression ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGAAGTGGA AAGAGAAGTT GGGGGATGGT GTCTATGACA CCTTCATGAT GATAGATGAA 
ACCAAATGTC CCCCCTGTTC AAATGTACTC TGCAATCCTT CTGAACCACC TCCACCCAGA 
AGACTAAATA TGACCACTGA GCAGTTTACA GGAGATCATA CTCAGCACTT TTTGGATGGA 
GGTGAGATGA AGGTAGAACA GCTGTTTCAA GAATTTGGCA ACAGAAAATC CAATACTATT 
CAGTCAGATG GCATCAGTGA CTCTGAAAAA TGCTCTCCTA CTGTTTCTCA GGGTAAAAGT 
TCAGATTGCT TGAATACAGT AAAATCCAAC AGTTCATCCA AGGCACCCAA AGTGGTGCCT 
CTGACTCCAG AACAAGCCCT GAAGCAATAT AAACACCACC TCACTGCCTA TGAGAAACTG 
GAAATAATTA ATTATCCAGA AATTTACTTT GTAGGTCCAA ATGCCAAGAA AAGACATGGA 
GTTATTGGTG GTCCCAATAA TGGAGGGTAT GATGATGCAG ATGGGGCCTA TATTCATGTA 
CCTCGAGACC ATCTAGCTTA TCGATATGAG GTGCTGAAAA TTATTGGCAA GGGGAGTTTT 
GGGCAGGTGG CCAGGGTCTA TGATCACAAA CTTCGACAGT ACGTGGCCCT AAAAATGGTG 
CGCAATGAGA AGCGCTTTCA TCGTCAAGCA GCTGAGGAGA TCCGGATTTT GGAGCATCTT 
AAGAAACAGG ATAAAACTGG TAGTATGAAC GTTATCCACA TGCTGGAAAG TTTCACATTC 
CGGAACCATG TTTGCATGGC CTTTGAATTG CTGAGCATAG ACCTTTATGA GCTGATTAAA 
AAAAATAAGT TTCAGGGTTT TAGCGTCCAG TTGGTACGCA AGTTTGCCCA GTCCATCTTG 
CAATCTTTGG ATGCCCTCCA CAAAAATAAG ATTATTCACT GCGATCTGAA GCCAGAAAAC 
ATTCTCCTGA AACACCACGG GCGCAGTTCA ACCAAGGTCA TTGACTTTGG GTCCAGCTGT 
TTCGAGTACC AGAAGCTCTA CACATATATC CAGTCTCGGT TCTACAGAGC TCCAGAAATC 
ATCTTAGGAA GCCGCTACAG CACACCAATT GACATATGGA GTTTTGGCTG CATCCTTGCA 
GAACTTTTAA CAGGACAGCC TCTCTTCCCT GGAGAGGATG AAGGAGACCA GTTGGCCTGC 
ATGATGGAGC TTCTAGGGAT GCCACCACCA AAACTTCTGG AGCAATCCAA ACGTGCCAAG 
TACTTTATTA ATTCCAAGGG CATACCCCGC TACTGCTCTG TGACTACCCA GGCAGATGGG 
AGGGTTGTGC TTGTGGGGGG TCGCTCACGT AGGGGTAAAA AGCGGGGTCC CCCAGGCAGC 
AAAGACTGGG GGACAGCACT GAAAGGGTGT GATGACTACT TGTTTATAGA GTTCTTGAAA 
AGGTGTCTTC ACTGGGACCC CTCTGCCCGC TTGACCCCAG CTCAAGCATT AAGACACCCT 
TGGATTAGCA AGTCTGTCCC CAGACCTCTC ACCACCATAG ACAAGGTGTC AGGGAAACGG 
GTAGTTAATC CTGCAAGTGC TTTCCAGGGA TTGGGTTCTA AGCTGCCTCC AGTTGTTGGA 
ATAGCCAATA AGCTTAAAGC TAACTTAATG TCAGAAACCA ATGGTAGTAT ACCCCTATGC 
AGTGTATTGC CAAAACTGAT TAGCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001004023.1
CDS	323..2029
Translation	MKWKEKLGDGVYDTFMMIDETKCPPCSNVLCNPSEPPPPRRLNMTTEQFTGDHTQHFLDGGEMKVEQLFQEFGNRKSNTIQSDGISDSEKCSPTVSQGKSSDCLNTVKSNSSSKAPKVVPLTPEQALKQYKHHLTAYEKLEIINYPEIYFVGPNAKKRHGVIGGPNNGGYDDADGAYIHVPRDHLAYRYEVLKIIGKGSFGQVARVYDHKLRQYVALKMVRNEKRFHRQAAEEIRILEHLKKQDKTGSMNVIHMLESFTFRNHVCMAFELLSIDLYELIKKNKFQGFSVQLVRKFAQSILQSLDALHKNKIIHCDLKPENILLKHHGRSSTKVIDFGSSCFEYQKLYTYIQSRFYRAPEIILGSRYSTPIDIWSFGCILAELLTGQPLFPGEDEGDQLACMMELLGMPPPKLLEQSKRAKYFINSKGIPRYCSVTTQADGRVVLVGGRSRRGKKRGPPGSKDWGTALKGCDDYLFIEFLKRCLHWDPSARLTPAQALRHPWISKSVPRPLTTIDKVSGKRVVNPASAFQGLGSKLPPVVGIANKLKANLMSETNGSIPLCSVLPKLIS

Target ORF information:

RefSeq Version	NM_001004023.2
Organism	Homo sapiens(human)
Definition	Homo sapiens dual specificity tyrosine phosphorylation regulated kinase 3 (DYRK3), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001004023.2

ORF Insert Sequence:

ATGAAGTGGA AAGAGAAGTT GGGGGATGGT GTCTATGACA CCTTCATGAT GATAGATGAA 
ACCAAATGTC CCCCCTGTTC AAATGTACTC TGCAATCCTT CTGAACCACC TCCACCCAGA 
AGACTAAATA TGACCACTGA GCAGTTTACA GGAGATCATA CTCAGCACTT TTTGGATGGA 
GGTGAGATGA AGGTAGAACA GCTGTTTCAA GAATTTGGCA ACAGAAAATC CAATACTATT 
CAGTCAGATG GCATCAGTGA CTCTGAAAAA TGCTCTCCTA CTGTTTCTCA GGGTAAAAGT 
TCAGATTGCT TGAATACAGT AAAATCCAAC AGTTCATCCA AGGCACCCAA AGTGGTGCCT 
CTGACTCCAG AACAAGCCCT GAAGCAATAT AAACACCACC TCACTGCCTA TGAGAAACTG 
GAAATAATTA ATTATCCAGA AATTTACTTT GTAGGTCCAA ATGCCAAGAA AAGACATGGA 
GTTATTGGTG GTCCCAATAA TGGAGGGTAT GATGATGCAG ATGGGGCCTA TATTCATGTA 
CCTCGAGACC ATCTAGCTTA TCGATATGAG GTGCTGAAAA TTATTGGCAA GGGGAGTTTT 
GGGCAGGTGG CCAGGGTCTA TGATCACAAA CTTCGACAGT ACGTGGCCCT AAAAATGGTG 
CGCAATGAGA AGCGCTTTCA TCGTCAAGCA GCTGAGGAGA TCCGGATTTT GGAGCATCTT 
AAGAAACAGG ATAAAACTGG TAGTATGAAC GTTATCCACA TGCTGGAAAG TTTCACATTC 
CGGAACCATG TTTGCATGGC CTTTGAATTG CTGAGCATAG ACCTTTATGA GCTGATTAAA 
AAAAATAAGT TTCAGGGTTT TAGCGTCCAG TTGGTACGCA AGTTTGCCCA GTCCATCTTG 
CAATCTTTGG ATGCCCTCCA CAAAAATAAG ATTATTCACT GCGATCTGAA GCCAGAAAAC 
ATTCTCCTGA AACACCACGG GCGCAGTTCA ACCAAGGTCA TTGACTTTGG GTCCAGCTGT 
TTCGAGTACC AGAAGCTCTA CACATATATC CAGTCTCGGT TCTACAGAGC TCCAGAAATC 
ATCTTAGGAA GCCGCTACAG CACACCAATT GACATATGGA GTTTTGGCTG CATCCTTGCA 
GAACTTTTAA CAGGACAGCC TCTCTTCCCT GGAGAGGATG AAGGAGACCA GTTGGCCTGC 
ATGATGGAGC TTCTAGGGAT GCCACCACCA AAACTTCTGG AGCAATCCAA ACGTGCCAAG 
TACTTTATTA ATTCCAAGGG CATACCCCGC TACTGCTCTG TGACTACCCA GGCAGATGGG 
AGGGTTGTGC TTGTGGGGGG TCGCTCACGT AGGGGTAAAA AGCGGGGTCC CCCAGGCAGC 
AAAGACTGGG GGACAGCACT GAAAGGGTGT GATGACTACT TGTTTATAGA GTTCTTGAAA 
AGGTGTCTTC ACTGGGACCC CTCTGCCCGC TTGACCCCAG CTCAAGCATT AAGACACCCT 
TGGATTAGCA AGTCTGTCCC CAGACCTCTC ACCACCATAG ACAAGGTGTC AGGGAAACGG 
GTAGTTAATC CTGCAAGTGC TTTCCAGGGA TTGGGTTCTA AGCTGCCTCC AGTTGTTGGA 
ATAGCCAATA AGCTTAAAGC TAACTTAATG TCAGAAACCA ATGGTAGTAT ACCCCTATGC 
AGTGTATTGC CAAAACTGAT TAGCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

DYRK3 ( NM_001004023.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001004023.1 Homo sapiens dual specificity tyrosine phosphorylation regulated kinase 3 (DYRK3), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu03508
Clone ID Related Accession (Same CDS sequence)	XM_005273315.4 , NM_001004023.2 , NM_001004023.1
Accession Version	NM_001004023.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1707bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-01-19
Organism	Homo sapiens(human)
Product	dual specificity tyrosine-phosphorylation-regulated kinase 3 isoform b
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AU126055.1, BC015501.1 and Y12735.2. Transcript Variant: This variant (2) contains an additional segment in the coding region compared to variant 1. The resulting isoform (b), also known as the isoform RED-S, contains a shorter and distinct N-terminus compared to isoform a. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC015501.1, SRR1803611.103653.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA1968968 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAAGTGGA AAGAGAAGTT GGGGGATGGT GTCTATGACA CCTTCATGAT GATAGATGAA 
ACCAAATGTC CCCCCTGTTC AAATGTACTC TGCAATCCTT CTGAACCACC TCCACCCAGA 
AGACTAAATA TGACCACTGA GCAGTTTACA GGAGATCATA CTCAGCACTT TTTGGATGGA 
GGTGAGATGA AGGTAGAACA GCTGTTTCAA GAATTTGGCA ACAGAAAATC CAATACTATT 
CAGTCAGATG GCATCAGTGA CTCTGAAAAA TGCTCTCCTA CTGTTTCTCA GGGTAAAAGT 
TCAGATTGCT TGAATACAGT AAAATCCAAC AGTTCATCCA AGGCACCCAA AGTGGTGCCT 
CTGACTCCAG AACAAGCCCT GAAGCAATAT AAACACCACC TCACTGCCTA TGAGAAACTG 
GAAATAATTA ATTATCCAGA AATTTACTTT GTAGGTCCAA ATGCCAAGAA AAGACATGGA 
GTTATTGGTG GTCCCAATAA TGGAGGGTAT GATGATGCAG ATGGGGCCTA TATTCATGTA 
CCTCGAGACC ATCTAGCTTA TCGATATGAG GTGCTGAAAA TTATTGGCAA GGGGAGTTTT 
GGGCAGGTGG CCAGGGTCTA TGATCACAAA CTTCGACAGT ACGTGGCCCT AAAAATGGTG 
CGCAATGAGA AGCGCTTTCA TCGTCAAGCA GCTGAGGAGA TCCGGATTTT GGAGCATCTT 
AAGAAACAGG ATAAAACTGG TAGTATGAAC GTTATCCACA TGCTGGAAAG TTTCACATTC 
CGGAACCATG TTTGCATGGC CTTTGAATTG CTGAGCATAG ACCTTTATGA GCTGATTAAA 
AAAAATAAGT TTCAGGGTTT TAGCGTCCAG TTGGTACGCA AGTTTGCCCA GTCCATCTTG 
CAATCTTTGG ATGCCCTCCA CAAAAATAAG ATTATTCACT GCGATCTGAA GCCAGAAAAC 
ATTCTCCTGA AACACCACGG GCGCAGTTCA ACCAAGGTCA TTGACTTTGG GTCCAGCTGT 
TTCGAGTACC AGAAGCTCTA CACATATATC CAGTCTCGGT TCTACAGAGC TCCAGAAATC 
ATCTTAGGAA GCCGCTACAG CACACCAATT GACATATGGA GTTTTGGCTG CATCCTTGCA 
GAACTTTTAA CAGGACAGCC TCTCTTCCCT GGAGAGGATG AAGGAGACCA GTTGGCCTGC 
ATGATGGAGC TTCTAGGGAT GCCACCACCA AAACTTCTGG AGCAATCCAA ACGTGCCAAG 
TACTTTATTA ATTCCAAGGG CATACCCCGC TACTGCTCTG TGACTACCCA GGCAGATGGG 
AGGGTTGTGC TTGTGGGGGG TCGCTCACGT AGGGGTAAAA AGCGGGGTCC CCCAGGCAGC 
AAAGACTGGG GGACAGCACT GAAAGGGTGT GATGACTACT TGTTTATAGA GTTCTTGAAA 
AGGTGTCTTC ACTGGGACCC CTCTGCCCGC TTGACCCCAG CTCAAGCATT AAGACACCCT 
TGGATTAGCA AGTCTGTCCC CAGACCTCTC ACCACCATAG ACAAGGTGTC AGGGAAACGG 
GTAGTTAATC CTGCAAGTGC TTTCCAGGGA TTGGGTTCTA AGCTGCCTCC AGTTGTTGGA 
ATAGCCAATA AGCTTAAAGC TAACTTAATG TCAGAAACCA ATGGTAGTAT ACCCCTATGC 
AGTGTATTGC CAAAACTGAT TAGCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001004023.1
CDS	323..2029
Translation	MKWKEKLGDGVYDTFMMIDETKCPPCSNVLCNPSEPPPPRRLNMTTEQFTGDHTQHFLDGGEMKVEQLFQEFGNRKSNTIQSDGISDSEKCSPTVSQGKSSDCLNTVKSNSSSKAPKVVPLTPEQALKQYKHHLTAYEKLEIINYPEIYFVGPNAKKRHGVIGGPNNGGYDDADGAYIHVPRDHLAYRYEVLKIIGKGSFGQVARVYDHKLRQYVALKMVRNEKRFHRQAAEEIRILEHLKKQDKTGSMNVIHMLESFTFRNHVCMAFELLSIDLYELIKKNKFQGFSVQLVRKFAQSILQSLDALHKNKIIHCDLKPENILLKHHGRSSTKVIDFGSSCFEYQKLYTYIQSRFYRAPEIILGSRYSTPIDIWSFGCILAELLTGQPLFPGEDEGDQLACMMELLGMPPPKLLEQSKRAKYFINSKGIPRYCSVTTQADGRVVLVGGRSRRGKKRGPPGSKDWGTALKGCDDYLFIEFLKRCLHWDPSARLTPAQALRHPWISKSVPRPLTTIDKVSGKRVVNPASAFQGLGSKLPPVVGIANKLKANLMSETNGSIPLCSVLPKLIS

Target ORF information:

RefSeq Version	NM_001004023.1
Organism	Homo sapiens(human)
Definition	Homo sapiens dual specificity tyrosine phosphorylation regulated kinase 3 (DYRK3), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001004023.1

ORF Insert Sequence:

ATGAAGTGGA AAGAGAAGTT GGGGGATGGT GTCTATGACA CCTTCATGAT GATAGATGAA 
ACCAAATGTC CCCCCTGTTC AAATGTACTC TGCAATCCTT CTGAACCACC TCCACCCAGA 
AGACTAAATA TGACCACTGA GCAGTTTACA GGAGATCATA CTCAGCACTT TTTGGATGGA 
GGTGAGATGA AGGTAGAACA GCTGTTTCAA GAATTTGGCA ACAGAAAATC CAATACTATT 
CAGTCAGATG GCATCAGTGA CTCTGAAAAA TGCTCTCCTA CTGTTTCTCA GGGTAAAAGT 
TCAGATTGCT TGAATACAGT AAAATCCAAC AGTTCATCCA AGGCACCCAA AGTGGTGCCT 
CTGACTCCAG AACAAGCCCT GAAGCAATAT AAACACCACC TCACTGCCTA TGAGAAACTG 
GAAATAATTA ATTATCCAGA AATTTACTTT GTAGGTCCAA ATGCCAAGAA AAGACATGGA 
GTTATTGGTG GTCCCAATAA TGGAGGGTAT GATGATGCAG ATGGGGCCTA TATTCATGTA 
CCTCGAGACC ATCTAGCTTA TCGATATGAG GTGCTGAAAA TTATTGGCAA GGGGAGTTTT 
GGGCAGGTGG CCAGGGTCTA TGATCACAAA CTTCGACAGT ACGTGGCCCT AAAAATGGTG 
CGCAATGAGA AGCGCTTTCA TCGTCAAGCA GCTGAGGAGA TCCGGATTTT GGAGCATCTT 
AAGAAACAGG ATAAAACTGG TAGTATGAAC GTTATCCACA TGCTGGAAAG TTTCACATTC 
CGGAACCATG TTTGCATGGC CTTTGAATTG CTGAGCATAG ACCTTTATGA GCTGATTAAA 
AAAAATAAGT TTCAGGGTTT TAGCGTCCAG TTGGTACGCA AGTTTGCCCA GTCCATCTTG 
CAATCTTTGG ATGCCCTCCA CAAAAATAAG ATTATTCACT GCGATCTGAA GCCAGAAAAC 
ATTCTCCTGA AACACCACGG GCGCAGTTCA ACCAAGGTCA TTGACTTTGG GTCCAGCTGT 
TTCGAGTACC AGAAGCTCTA CACATATATC CAGTCTCGGT TCTACAGAGC TCCAGAAATC 
ATCTTAGGAA GCCGCTACAG CACACCAATT GACATATGGA GTTTTGGCTG CATCCTTGCA 
GAACTTTTAA CAGGACAGCC TCTCTTCCCT GGAGAGGATG AAGGAGACCA GTTGGCCTGC 
ATGATGGAGC TTCTAGGGAT GCCACCACCA AAACTTCTGG AGCAATCCAA ACGTGCCAAG 
TACTTTATTA ATTCCAAGGG CATACCCCGC TACTGCTCTG TGACTACCCA GGCAGATGGG 
AGGGTTGTGC TTGTGGGGGG TCGCTCACGT AGGGGTAAAA AGCGGGGTCC CCCAGGCAGC 
AAAGACTGGG GGACAGCACT GAAAGGGTGT GATGACTACT TGTTTATAGA GTTCTTGAAA 
AGGTGTCTTC ACTGGGACCC CTCTGCCCGC TTGACCCCAG CTCAAGCATT AAGACACCCT 
TGGATTAGCA AGTCTGTCCC CAGACCTCTC ACCACCATAG ACAAGGTGTC AGGGAAACGG 
GTAGTTAATC CTGCAAGTGC TTTCCAGGGA TTGGGTTCTA AGCTGCCTCC AGTTGTTGGA 
ATAGCCAATA AGCTTAAAGC TAACTTAATG TCAGAAACCA ATGGTAGTAT ACCCCTATGC 
AGTGTATTGC CAAAACTGAT TAGCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

DYRK3 ( NM_003582.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_003573.2 Homo sapiens dual specificity tyrosine phosphorylation regulated kinase 3 (DYRK3), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu30360
Clone ID Related Accession (Same CDS sequence)	NM_003582.2 , NM_003582.3
Accession Version	NM_003582.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1767bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-15
Organism	Homo sapiens(human)
Product	dual specificity tyrosine-phosphorylation-regulated kinase 3 isoform a
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AU126055.1, Y12735.2 and BC015501.1. On Aug 31, 2004 this sequence version replaced NM_003582.1. Transcript Variant: This variant (1) represents the shorter transcript, but encodes the longer isoform (a), also known as the RED-L isoform. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK308082.1, AY590695.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGGAGGCA CAGCTCGTGG GCCTGGGCGG AAGGATGCGG GGCCGCCTGG GGCCGGGCTC 
CCGCCCCAGC AGCGGAGGTT GGGGGATGGT GTCTATGACA CCTTCATGAT GATAGATGAA 
ACCAAATGTC CCCCCTGTTC AAATGTACTC TGCAATCCTT CTGAACCACC TCCACCCAGA 
AGACTAAATA TGACCACTGA GCAGTTTACA GGAGATCATA CTCAGCACTT TTTGGATGGA 
GGTGAGATGA AGGTAGAACA GCTGTTTCAA GAATTTGGCA ACAGAAAATC CAATACTATT 
CAGTCAGATG GCATCAGTGA CTCTGAAAAA TGCTCTCCTA CTGTTTCTCA GGGTAAAAGT 
TCAGATTGCT TGAATACAGT AAAATCCAAC AGTTCATCCA AGGCACCCAA AGTGGTGCCT 
CTGACTCCAG AACAAGCCCT GAAGCAATAT AAACACCACC TCACTGCCTA TGAGAAACTG 
GAAATAATTA ATTATCCAGA AATTTACTTT GTAGGTCCAA ATGCCAAGAA AAGACATGGA 
GTTATTGGTG GTCCCAATAA TGGAGGGTAT GATGATGCAG ATGGGGCCTA TATTCATGTA 
CCTCGAGACC ATCTAGCTTA TCGATATGAG GTGCTGAAAA TTATTGGCAA GGGGAGTTTT 
GGGCAGGTGG CCAGGGTCTA TGATCACAAA CTTCGACAGT ACGTGGCCCT AAAAATGGTG 
CGCAATGAGA AGCGCTTTCA TCGTCAAGCA GCTGAGGAGA TCCGGATTTT GGAGCATCTT 
AAGAAACAGG ATAAAACTGG TAGTATGAAC GTTATCCACA TGCTGGAAAG TTTCACATTC 
CGGAACCATG TTTGCATGGC CTTTGAATTG CTGAGCATAG ACCTTTATGA GCTGATTAAA 
AAAAATAAGT TTCAGGGTTT TAGCGTCCAG TTGGTACGCA AGTTTGCCCA GTCCATCTTG 
CAATCTTTGG ATGCCCTCCA CAAAAATAAG ATTATTCACT GCGATCTGAA GCCAGAAAAC 
ATTCTCCTGA AACACCACGG GCGCAGTTCA ACCAAGGTCA TTGACTTTGG GTCCAGCTGT 
TTCGAGTACC AGAAGCTCTA CACATATATC CAGTCTCGGT TCTACAGAGC TCCAGAAATC 
ATCTTAGGAA GCCGCTACAG CACACCAATT GACATATGGA GTTTTGGCTG CATCCTTGCA 
GAACTTTTAA CAGGACAGCC TCTCTTCCCT GGAGAGGATG AAGGAGACCA GTTGGCCTGC 
ATGATGGAGC TTCTAGGGAT GCCACCACCA AAACTTCTGG AGCAATCCAA ACGTGCCAAG 
TACTTTATTA ATTCCAAGGG CATACCCCGC TACTGCTCTG TGACTACCCA GGCAGATGGG 
AGGGTTGTGC TTGTGGGGGG TCGCTCACGT AGGGGTAAAA AGCGGGGTCC CCCAGGCAGC 
AAAGACTGGG GGACAGCACT GAAAGGGTGT GATGACTACT TGTTTATAGA GTTCTTGAAA 
AGGTGTCTTC ACTGGGACCC CTCTGCCCGC TTGACCCCAG CTCAAGCATT AAGACACCCT 
TGGATTAGCA AGTCTGTCCC CAGACCTCTC ACCACCATAG ACAAGGTGTC AGGGAAACGG 
GTAGTTAATC CTGCAAGTGC TTTCCAGGGA TTGGGTTCTA AGCTGCCTCC AGTTGTTGGA 
ATAGCCAATA AGCTTAAAGC TAACTTAATG TCAGAAACCA ATGGTAGTAT ACCCCTATGC 
AGTGTATTGC CAAAACTGAT TAGCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_003573.2
CDS	169..1935
Translation	MGGTARGPGRKDAGPPGAGLPPQQRRLGDGVYDTFMMIDETKCPPCSNVLCNPSEPPPPRRLNMTTEQFTGDHTQHFLDGGEMKVEQLFQEFGNRKSNTIQSDGISDSEKCSPTVSQGKSSDCLNTVKSNSSSKAPKVVPLTPEQALKQYKHHLTAYEKLEIINYPEIYFVGPNAKKRHGVIGGPNNGGYDDADGAYIHVPRDHLAYRYEVLKIIGKGSFGQVARVYDHKLRQYVALKMVRNEKRFHRQAAEEIRILEHLKKQDKTGSMNVIHMLESFTFRNHVCMAFELLSIDLYELIKKNKFQGFSVQLVRKFAQSILQSLDALHKNKIIHCDLKPENILLKHHGRSSTKVIDFGSSCFEYQKLYTYIQSRFYRAPEIILGSRYSTPIDIWSFGCILAELLTGQPLFPGEDEGDQLACMMELLGMPPPKLLEQSKRAKYFINSKGIPRYCSVTTQADGRVVLVGGRSRRGKKRGPPGSKDWGTALKGCDDYLFIEFLKRCLHWDPSARLTPAQALRHPWISKSVPRPLTTIDKVSGKRVVNPASAFQGLGSKLPPVVGIANKLKANLMSETNGSIPLCSVLPKLIS

Target ORF information:

RefSeq Version	NM_003582.2
Organism	Homo sapiens(human)
Definition	Homo sapiens dual specificity tyrosine phosphorylation regulated kinase 3 (DYRK3), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_003582.2

ORF Insert Sequence:

ATGGGAGGCA CAGCTCGTGG GCCTGGGCGG AAGGATGCGG GGCCGCCTGG GGCCGGGCTC 
CCGCCCCAGC AGCGGAGGTT GGGGGATGGT GTCTATGACA CCTTCATGAT GATAGATGAA 
ACCAAATGTC CCCCCTGTTC AAATGTACTC TGCAATCCTT CTGAACCACC TCCACCCAGA 
AGACTAAATA TGACCACTGA GCAGTTTACA GGAGATCATA CTCAGCACTT TTTGGATGGA 
GGTGAGATGA AGGTAGAACA GCTGTTTCAA GAATTTGGCA ACAGAAAATC CAATACTATT 
CAGTCAGATG GCATCAGTGA CTCTGAAAAA TGCTCTCCTA CTGTTTCTCA GGGTAAAAGT 
TCAGATTGCT TGAATACAGT AAAATCCAAC AGTTCATCCA AGGCACCCAA AGTGGTGCCT 
CTGACTCCAG AACAAGCCCT GAAGCAATAT AAACACCACC TCACTGCCTA TGAGAAACTG 
GAAATAATTA ATTATCCAGA AATTTACTTT GTAGGTCCAA ATGCCAAGAA AAGACATGGA 
GTTATTGGTG GTCCCAATAA TGGAGGGTAT GATGATGCAG ATGGGGCCTA TATTCATGTA 
CCTCGAGACC ATCTAGCTTA TCGATATGAG GTGCTGAAAA TTATTGGCAA GGGGAGTTTT 
GGGCAGGTGG CCAGGGTCTA TGATCACAAA CTTCGACAGT ACGTGGCCCT AAAAATGGTG 
CGCAATGAGA AGCGCTTTCA TCGTCAAGCA GCTGAGGAGA TCCGGATTTT GGAGCATCTT 
AAGAAACAGG ATAAAACTGG TAGTATGAAC GTTATCCACA TGCTGGAAAG TTTCACATTC 
CGGAACCATG TTTGCATGGC CTTTGAATTG CTGAGCATAG ACCTTTATGA GCTGATTAAA 
AAAAATAAGT TTCAGGGTTT TAGCGTCCAG TTGGTACGCA AGTTTGCCCA GTCCATCTTG 
CAATCTTTGG ATGCCCTCCA CAAAAATAAG ATTATTCACT GCGATCTGAA GCCAGAAAAC 
ATTCTCCTGA AACACCACGG GCGCAGTTCA ACCAAGGTCA TTGACTTTGG GTCCAGCTGT 
TTCGAGTACC AGAAGCTCTA CACATATATC CAGTCTCGGT TCTACAGAGC TCCAGAAATC 
ATCTTAGGAA GCCGCTACAG CACACCAATT GACATATGGA GTTTTGGCTG CATCCTTGCA 
GAACTTTTAA CAGGACAGCC TCTCTTCCCT GGAGAGGATG AAGGAGACCA GTTGGCCTGC 
ATGATGGAGC TTCTAGGGAT GCCACCACCA AAACTTCTGG AGCAATCCAA ACGTGCCAAG 
TACTTTATTA ATTCCAAGGG CATACCCCGC TACTGCTCTG TGACTACCCA GGCAGATGGG 
AGGGTTGTGC TTGTGGGGGG TCGCTCACGT AGGGGTAAAA AGCGGGGTCC CCCAGGCAGC 
AAAGACTGGG GGACAGCACT GAAAGGGTGT GATGACTACT TGTTTATAGA GTTCTTGAAA 
AGGTGTCTTC ACTGGGACCC CTCTGCCCGC TTGACCCCAG CTCAAGCATT AAGACACCCT 
TGGATTAGCA AGTCTGTCCC CAGACCTCTC ACCACCATAG ACAAGGTGTC AGGGAAACGG 
GTAGTTAATC CTGCAAGTGC TTTCCAGGGA TTGGGTTCTA AGCTGCCTCC AGTTGTTGGA 
ATAGCCAATA AGCTTAAAGC TAACTTAATG TCAGAAACCA ATGGTAGTAT ACCCCTATGC 
AGTGTATTGC CAAAACTGAT TAGCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

DYRK3 ( NM_003582.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_003573.2 Homo sapiens dual specificity tyrosine phosphorylation regulated kinase 3 (DYRK3), transcript variant 1, mRNA.

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CloneID	OHu30360
Clone ID Related Accession (Same CDS sequence)	NM_003582.2 , NM_003582.3
Accession Version	NM_003582.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1767bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-06-01
Organism	Homo sapiens(human)
Product	dual specificity tyrosine-phosphorylation-regulated kinase 3 isoform a
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AU126055.1, Y12735.2, BC015501.1 and AL591846.15. On Jun 2, 2019 this sequence version replaced NM_003582.2. Transcript Variant: This variant (1) represents the shorter transcript, but encodes the longer isoform (a), also known as the RED-L isoform. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803614.19743.1, AK308082.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGGAGGCA CAGCTCGTGG GCCTGGGCGG AAGGATGCGG GGCCGCCTGG GGCCGGGCTC 
CCGCCCCAGC AGCGGAGGTT GGGGGATGGT GTCTATGACA CCTTCATGAT GATAGATGAA 
ACCAAATGTC CCCCCTGTTC AAATGTACTC TGCAATCCTT CTGAACCACC TCCACCCAGA 
AGACTAAATA TGACCACTGA GCAGTTTACA GGAGATCATA CTCAGCACTT TTTGGATGGA 
GGTGAGATGA AGGTAGAACA GCTGTTTCAA GAATTTGGCA ACAGAAAATC CAATACTATT 
CAGTCAGATG GCATCAGTGA CTCTGAAAAA TGCTCTCCTA CTGTTTCTCA GGGTAAAAGT 
TCAGATTGCT TGAATACAGT AAAATCCAAC AGTTCATCCA AGGCACCCAA AGTGGTGCCT 
CTGACTCCAG AACAAGCCCT GAAGCAATAT AAACACCACC TCACTGCCTA TGAGAAACTG 
GAAATAATTA ATTATCCAGA AATTTACTTT GTAGGTCCAA ATGCCAAGAA AAGACATGGA 
GTTATTGGTG GTCCCAATAA TGGAGGGTAT GATGATGCAG ATGGGGCCTA TATTCATGTA 
CCTCGAGACC ATCTAGCTTA TCGATATGAG GTGCTGAAAA TTATTGGCAA GGGGAGTTTT 
GGGCAGGTGG CCAGGGTCTA TGATCACAAA CTTCGACAGT ACGTGGCCCT AAAAATGGTG 
CGCAATGAGA AGCGCTTTCA TCGTCAAGCA GCTGAGGAGA TCCGGATTTT GGAGCATCTT 
AAGAAACAGG ATAAAACTGG TAGTATGAAC GTTATCCACA TGCTGGAAAG TTTCACATTC 
CGGAACCATG TTTGCATGGC CTTTGAATTG CTGAGCATAG ACCTTTATGA GCTGATTAAA 
AAAAATAAGT TTCAGGGTTT TAGCGTCCAG TTGGTACGCA AGTTTGCCCA GTCCATCTTG 
CAATCTTTGG ATGCCCTCCA CAAAAATAAG ATTATTCACT GCGATCTGAA GCCAGAAAAC 
ATTCTCCTGA AACACCACGG GCGCAGTTCA ACCAAGGTCA TTGACTTTGG GTCCAGCTGT 
TTCGAGTACC AGAAGCTCTA CACATATATC CAGTCTCGGT TCTACAGAGC TCCAGAAATC 
ATCTTAGGAA GCCGCTACAG CACACCAATT GACATATGGA GTTTTGGCTG CATCCTTGCA 
GAACTTTTAA CAGGACAGCC TCTCTTCCCT GGAGAGGATG AAGGAGACCA GTTGGCCTGC 
ATGATGGAGC TTCTAGGGAT GCCACCACCA AAACTTCTGG AGCAATCCAA ACGTGCCAAG 
TACTTTATTA ATTCCAAGGG CATACCCCGC TACTGCTCTG TGACTACCCA GGCAGATGGG 
AGGGTTGTGC TTGTGGGGGG TCGCTCACGT AGGGGTAAAA AGCGGGGTCC CCCAGGCAGC 
AAAGACTGGG GGACAGCACT GAAAGGGTGT GATGACTACT TGTTTATAGA GTTCTTGAAA 
AGGTGTCTTC ACTGGGACCC CTCTGCCCGC TTGACCCCAG CTCAAGCATT AAGACACCCT 
TGGATTAGCA AGTCTGTCCC CAGACCTCTC ACCACCATAG ACAAGGTGTC AGGGAAACGG 
GTAGTTAATC CTGCAAGTGC TTTCCAGGGA TTGGGTTCTA AGCTGCCTCC AGTTGTTGGA 
ATAGCCAATA AGCTTAAAGC TAACTTAATG TCAGAAACCA ATGGTAGTAT ACCCCTATGC 
AGTGTATTGC CAAAACTGAT TAGCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_003573.2
CDS	169..1935
Translation	MGGTARGPGRKDAGPPGAGLPPQQRRLGDGVYDTFMMIDETKCPPCSNVLCNPSEPPPPRRLNMTTEQFTGDHTQHFLDGGEMKVEQLFQEFGNRKSNTIQSDGISDSEKCSPTVSQGKSSDCLNTVKSNSSSKAPKVVPLTPEQALKQYKHHLTAYEKLEIINYPEIYFVGPNAKKRHGVIGGPNNGGYDDADGAYIHVPRDHLAYRYEVLKIIGKGSFGQVARVYDHKLRQYVALKMVRNEKRFHRQAAEEIRILEHLKKQDKTGSMNVIHMLESFTFRNHVCMAFELLSIDLYELIKKNKFQGFSVQLVRKFAQSILQSLDALHKNKIIHCDLKPENILLKHHGRSSTKVIDFGSSCFEYQKLYTYIQSRFYRAPEIILGSRYSTPIDIWSFGCILAELLTGQPLFPGEDEGDQLACMMELLGMPPPKLLEQSKRAKYFINSKGIPRYCSVTTQADGRVVLVGGRSRRGKKRGPPGSKDWGTALKGCDDYLFIEFLKRCLHWDPSARLTPAQALRHPWISKSVPRPLTTIDKVSGKRVVNPASAFQGLGSKLPPVVGIANKLKANLMSETNGSIPLCSVLPKLIS

Target ORF information:

RefSeq Version	NM_003582.3
Organism	Homo sapiens(human)
Definition	Homo sapiens dual specificity tyrosine phosphorylation regulated kinase 3 (DYRK3), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_003582.3

ORF Insert Sequence:

ATGGGAGGCA CAGCTCGTGG GCCTGGGCGG AAGGATGCGG GGCCGCCTGG GGCCGGGCTC 
CCGCCCCAGC AGCGGAGGTT GGGGGATGGT GTCTATGACA CCTTCATGAT GATAGATGAA 
ACCAAATGTC CCCCCTGTTC AAATGTACTC TGCAATCCTT CTGAACCACC TCCACCCAGA 
AGACTAAATA TGACCACTGA GCAGTTTACA GGAGATCATA CTCAGCACTT TTTGGATGGA 
GGTGAGATGA AGGTAGAACA GCTGTTTCAA GAATTTGGCA ACAGAAAATC CAATACTATT 
CAGTCAGATG GCATCAGTGA CTCTGAAAAA TGCTCTCCTA CTGTTTCTCA GGGTAAAAGT 
TCAGATTGCT TGAATACAGT AAAATCCAAC AGTTCATCCA AGGCACCCAA AGTGGTGCCT 
CTGACTCCAG AACAAGCCCT GAAGCAATAT AAACACCACC TCACTGCCTA TGAGAAACTG 
GAAATAATTA ATTATCCAGA AATTTACTTT GTAGGTCCAA ATGCCAAGAA AAGACATGGA 
GTTATTGGTG GTCCCAATAA TGGAGGGTAT GATGATGCAG ATGGGGCCTA TATTCATGTA 
CCTCGAGACC ATCTAGCTTA TCGATATGAG GTGCTGAAAA TTATTGGCAA GGGGAGTTTT 
GGGCAGGTGG CCAGGGTCTA TGATCACAAA CTTCGACAGT ACGTGGCCCT AAAAATGGTG 
CGCAATGAGA AGCGCTTTCA TCGTCAAGCA GCTGAGGAGA TCCGGATTTT GGAGCATCTT 
AAGAAACAGG ATAAAACTGG TAGTATGAAC GTTATCCACA TGCTGGAAAG TTTCACATTC 
CGGAACCATG TTTGCATGGC CTTTGAATTG CTGAGCATAG ACCTTTATGA GCTGATTAAA 
AAAAATAAGT TTCAGGGTTT TAGCGTCCAG TTGGTACGCA AGTTTGCCCA GTCCATCTTG 
CAATCTTTGG ATGCCCTCCA CAAAAATAAG ATTATTCACT GCGATCTGAA GCCAGAAAAC 
ATTCTCCTGA AACACCACGG GCGCAGTTCA ACCAAGGTCA TTGACTTTGG GTCCAGCTGT 
TTCGAGTACC AGAAGCTCTA CACATATATC CAGTCTCGGT TCTACAGAGC TCCAGAAATC 
ATCTTAGGAA GCCGCTACAG CACACCAATT GACATATGGA GTTTTGGCTG CATCCTTGCA 
GAACTTTTAA CAGGACAGCC TCTCTTCCCT GGAGAGGATG AAGGAGACCA GTTGGCCTGC 
ATGATGGAGC TTCTAGGGAT GCCACCACCA AAACTTCTGG AGCAATCCAA ACGTGCCAAG 
TACTTTATTA ATTCCAAGGG CATACCCCGC TACTGCTCTG TGACTACCCA GGCAGATGGG 
AGGGTTGTGC TTGTGGGGGG TCGCTCACGT AGGGGTAAAA AGCGGGGTCC CCCAGGCAGC 
AAAGACTGGG GGACAGCACT GAAAGGGTGT GATGACTACT TGTTTATAGA GTTCTTGAAA 
AGGTGTCTTC ACTGGGACCC CTCTGCCCGC TTGACCCCAG CTCAAGCATT AAGACACCCT 
TGGATTAGCA AGTCTGTCCC CAGACCTCTC ACCACCATAG ACAAGGTGTC AGGGAAACGG 
GTAGTTAATC CTGCAAGTGC TTTCCAGGGA TTGGGTTCTA AGCTGCCTCC AGTTGTTGGA 
ATAGCCAATA AGCTTAAAGC TAACTTAATG TCAGAAACCA ATGGTAGTAT ACCCCTATGC 
AGTGTATTGC CAAAACTGAT TAGCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

DYRK3 ( XM_005273315.4 ) cDNA ORF clone, Homo sapiens(human) -> XP_005273372.1 Homo sapiens dual specificity tyrosine phosphorylation regulated kinase 3 (DYRK3), transcript variant X1, mRNA.

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CloneID	OHu03508
Clone ID Related Accession (Same CDS sequence)	XM_005273315.4 , NM_001004023.2 , NM_001004023.1
Accession Version	XM_005273315.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1707bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	dual specificity tyrosine-phosphorylation-regulated kinase 3 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000001.11) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_005273315.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAAGTGGA AAGAGAAGTT GGGGGATGGT GTCTATGACA CCTTCATGAT GATAGATGAA 
ACCAAATGTC CCCCCTGTTC AAATGTACTC TGCAATCCTT CTGAACCACC TCCACCCAGA 
AGACTAAATA TGACCACTGA GCAGTTTACA GGAGATCATA CTCAGCACTT TTTGGATGGA 
GGTGAGATGA AGGTAGAACA GCTGTTTCAA GAATTTGGCA ACAGAAAATC CAATACTATT 
CAGTCAGATG GCATCAGTGA CTCTGAAAAA TGCTCTCCTA CTGTTTCTCA GGGTAAAAGT 
TCAGATTGCT TGAATACAGT AAAATCCAAC AGTTCATCCA AGGCACCCAA AGTGGTGCCT 
CTGACTCCAG AACAAGCCCT GAAGCAATAT AAACACCACC TCACTGCCTA TGAGAAACTG 
GAAATAATTA ATTATCCAGA AATTTACTTT GTAGGTCCAA ATGCCAAGAA AAGACATGGA 
GTTATTGGTG GTCCCAATAA TGGAGGGTAT GATGATGCAG ATGGGGCCTA TATTCATGTA 
CCTCGAGACC ATCTAGCTTA TCGATATGAG GTGCTGAAAA TTATTGGCAA GGGGAGTTTT 
GGGCAGGTGG CCAGGGTCTA TGATCACAAA CTTCGACAGT ACGTGGCCCT AAAAATGGTG 
CGCAATGAGA AGCGCTTTCA TCGTCAAGCA GCTGAGGAGA TCCGGATTTT GGAGCATCTT 
AAGAAACAGG ATAAAACTGG TAGTATGAAC GTTATCCACA TGCTGGAAAG TTTCACATTC 
CGGAACCATG TTTGCATGGC CTTTGAATTG CTGAGCATAG ACCTTTATGA GCTGATTAAA 
AAAAATAAGT TTCAGGGTTT TAGCGTCCAG TTGGTACGCA AGTTTGCCCA GTCCATCTTG 
CAATCTTTGG ATGCCCTCCA CAAAAATAAG ATTATTCACT GCGATCTGAA GCCAGAAAAC 
ATTCTCCTGA AACACCACGG GCGCAGTTCA ACCAAGGTCA TTGACTTTGG GTCCAGCTGT 
TTCGAGTACC AGAAGCTCTA CACATATATC CAGTCTCGGT TCTACAGAGC TCCAGAAATC 
ATCTTAGGAA GCCGCTACAG CACACCAATT GACATATGGA GTTTTGGCTG CATCCTTGCA 
GAACTTTTAA CAGGACAGCC TCTCTTCCCT GGAGAGGATG AAGGAGACCA GTTGGCCTGC 
ATGATGGAGC TTCTAGGGAT GCCACCACCA AAACTTCTGG AGCAATCCAA ACGTGCCAAG 
TACTTTATTA ATTCCAAGGG CATACCCCGC TACTGCTCTG TGACTACCCA GGCAGATGGG 
AGGGTTGTGC TTGTGGGGGG TCGCTCACGT AGGGGTAAAA AGCGGGGTCC CCCAGGCAGC 
AAAGACTGGG GGACAGCACT GAAAGGGTGT GATGACTACT TGTTTATAGA GTTCTTGAAA 
AGGTGTCTTC ACTGGGACCC CTCTGCCCGC TTGACCCCAG CTCAAGCATT AAGACACCCT 
TGGATTAGCA AGTCTGTCCC CAGACCTCTC ACCACCATAG ACAAGGTGTC AGGGAAACGG 
GTAGTTAATC CTGCAAGTGC TTTCCAGGGA TTGGGTTCTA AGCTGCCTCC AGTTGTTGGA 
ATAGCCAATA AGCTTAAAGC TAACTTAATG TCAGAAACCA ATGGTAGTAT ACCCCTATGC 
AGTGTATTGC CAAAACTGAT TAGCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005273372.1
CDS	167..1873
Translation	MKWKEKLGDGVYDTFMMIDETKCPPCSNVLCNPSEPPPPRRLNMTTEQFTGDHTQHFLDGGEMKVEQLFQEFGNRKSNTIQSDGISDSEKCSPTVSQGKSSDCLNTVKSNSSSKAPKVVPLTPEQALKQYKHHLTAYEKLEIINYPEIYFVGPNAKKRHGVIGGPNNGGYDDADGAYIHVPRDHLAYRYEVLKIIGKGSFGQVARVYDHKLRQYVALKMVRNEKRFHRQAAEEIRILEHLKKQDKTGSMNVIHMLESFTFRNHVCMAFELLSIDLYELIKKNKFQGFSVQLVRKFAQSILQSLDALHKNKIIHCDLKPENILLKHHGRSSTKVIDFGSSCFEYQKLYTYIQSRFYRAPEIILGSRYSTPIDIWSFGCILAELLTGQPLFPGEDEGDQLACMMELLGMPPPKLLEQSKRAKYFINSKGIPRYCSVTTQADGRVVLVGGRSRRGKKRGPPGSKDWGTALKGCDDYLFIEFLKRCLHWDPSARLTPAQALRHPWISKSVPRPLTTIDKVSGKRVVNPASAFQGLGSKLPPVVGIANKLKANLMSETNGSIPLCSVLPKLIS

Target ORF information:

RefSeq Version	XM_005273315.4
Organism	Homo sapiens(human)
Definition	Homo sapiens dual specificity tyrosine phosphorylation regulated kinase 3 (DYRK3), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005273315.4

ORF Insert Sequence:

ATGAAGTGGA AAGAGAAGTT GGGGGATGGT GTCTATGACA CCTTCATGAT GATAGATGAA 
ACCAAATGTC CCCCCTGTTC AAATGTACTC TGCAATCCTT CTGAACCACC TCCACCCAGA 
AGACTAAATA TGACCACTGA GCAGTTTACA GGAGATCATA CTCAGCACTT TTTGGATGGA 
GGTGAGATGA AGGTAGAACA GCTGTTTCAA GAATTTGGCA ACAGAAAATC CAATACTATT 
CAGTCAGATG GCATCAGTGA CTCTGAAAAA TGCTCTCCTA CTGTTTCTCA GGGTAAAAGT 
TCAGATTGCT TGAATACAGT AAAATCCAAC AGTTCATCCA AGGCACCCAA AGTGGTGCCT 
CTGACTCCAG AACAAGCCCT GAAGCAATAT AAACACCACC TCACTGCCTA TGAGAAACTG 
GAAATAATTA ATTATCCAGA AATTTACTTT GTAGGTCCAA ATGCCAAGAA AAGACATGGA 
GTTATTGGTG GTCCCAATAA TGGAGGGTAT GATGATGCAG ATGGGGCCTA TATTCATGTA 
CCTCGAGACC ATCTAGCTTA TCGATATGAG GTGCTGAAAA TTATTGGCAA GGGGAGTTTT 
GGGCAGGTGG CCAGGGTCTA TGATCACAAA CTTCGACAGT ACGTGGCCCT AAAAATGGTG 
CGCAATGAGA AGCGCTTTCA TCGTCAAGCA GCTGAGGAGA TCCGGATTTT GGAGCATCTT 
AAGAAACAGG ATAAAACTGG TAGTATGAAC GTTATCCACA TGCTGGAAAG TTTCACATTC 
CGGAACCATG TTTGCATGGC CTTTGAATTG CTGAGCATAG ACCTTTATGA GCTGATTAAA 
AAAAATAAGT TTCAGGGTTT TAGCGTCCAG TTGGTACGCA AGTTTGCCCA GTCCATCTTG 
CAATCTTTGG ATGCCCTCCA CAAAAATAAG ATTATTCACT GCGATCTGAA GCCAGAAAAC 
ATTCTCCTGA AACACCACGG GCGCAGTTCA ACCAAGGTCA TTGACTTTGG GTCCAGCTGT 
TTCGAGTACC AGAAGCTCTA CACATATATC CAGTCTCGGT TCTACAGAGC TCCAGAAATC 
ATCTTAGGAA GCCGCTACAG CACACCAATT GACATATGGA GTTTTGGCTG CATCCTTGCA 
GAACTTTTAA CAGGACAGCC TCTCTTCCCT GGAGAGGATG AAGGAGACCA GTTGGCCTGC 
ATGATGGAGC TTCTAGGGAT GCCACCACCA AAACTTCTGG AGCAATCCAA ACGTGCCAAG 
TACTTTATTA ATTCCAAGGG CATACCCCGC TACTGCTCTG TGACTACCCA GGCAGATGGG 
AGGGTTGTGC TTGTGGGGGG TCGCTCACGT AGGGGTAAAA AGCGGGGTCC CCCAGGCAGC 
AAAGACTGGG GGACAGCACT GAAAGGGTGT GATGACTACT TGTTTATAGA GTTCTTGAAA 
AGGTGTCTTC ACTGGGACCC CTCTGCCCGC TTGACCCCAG CTCAAGCATT AAGACACCCT 
TGGATTAGCA AGTCTGTCCC CAGACCTCTC ACCACCATAG ACAAGGTGTC AGGGAAACGG 
GTAGTTAATC CTGCAAGTGC TTTCCAGGGA TTGGGTTCTA AGCTGCCTCC AGTTGTTGGA 
ATAGCCAATA AGCTTAAAGC TAACTTAATG TCAGAAACCA ATGGTAGTAT ACCCCTATGC 
AGTGTATTGC CAAAACTGAT TAGCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

DYRK3 ( XM_011510061.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011508363.1 Homo sapiens dual specificity tyrosine phosphorylation regulated kinase 3 (DYRK3), transcript variant X2, mRNA.

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CloneID	OHu61775
Clone ID Related Accession (Same CDS sequence)	XM_011510061.2
Accession Version	XM_011510061.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1662bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	dual specificity tyrosine-phosphorylation-regulated kinase 3 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000001.11) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011510061.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGATGATAG ATGAAACCAA ATGTCCCCCC TGTTCAAATG TACTCTGCAA TCCTTCTGAA 
CCACCTCCAC CCAGAAGACT AAATATGACC ACTGAGCAGT TTACAGGAGA TCATACTCAG 
CACTTTTTGG ATGGAGGTGA GATGAAGGTA GAACAGCTGT TTCAAGAATT TGGCAACAGA 
AAATCCAATA CTATTCAGTC AGATGGCATC AGTGACTCTG AAAAATGCTC TCCTACTGTT 
TCTCAGGGTA AAAGTTCAGA TTGCTTGAAT ACAGTAAAAT CCAACAGTTC ATCCAAGGCA 
CCCAAAGTGG TGCCTCTGAC TCCAGAACAA GCCCTGAAGC AATATAAACA CCACCTCACT 
GCCTATGAGA AACTGGAAAT AATTAATTAT CCAGAAATTT ACTTTGTAGG TCCAAATGCC 
AAGAAAAGAC ATGGAGTTAT TGGTGGTCCC AATAATGGAG GGTATGATGA TGCAGATGGG 
GCCTATATTC ATGTACCTCG AGACCATCTA GCTTATCGAT ATGAGGTGCT GAAAATTATT 
GGCAAGGGGA GTTTTGGGCA GGTGGCCAGG GTCTATGATC ACAAACTTCG ACAGTACGTG 
GCCCTAAAAA TGGTGCGCAA TGAGAAGCGC TTTCATCGTC AAGCAGCTGA GGAGATCCGG 
ATTTTGGAGC ATCTTAAGAA ACAGGATAAA ACTGGTAGTA TGAACGTTAT CCACATGCTG 
GAAAGTTTCA CATTCCGGAA CCATGTTTGC ATGGCCTTTG AATTGCTGAG CATAGACCTT 
TATGAGCTGA TTAAAAAAAA TAAGTTTCAG GGTTTTAGCG TCCAGTTGGT ACGCAAGTTT 
GCCCAGTCCA TCTTGCAATC TTTGGATGCC CTCCACAAAA ATAAGATTAT TCACTGCGAT 
CTGAAGCCAG AAAACATTCT CCTGAAACAC CACGGGCGCA GTTCAACCAA GGTCATTGAC 
TTTGGGTCCA GCTGTTTCGA GTACCAGAAG CTCTACACAT ATATCCAGTC TCGGTTCTAC 
AGAGCTCCAG AAATCATCTT AGGAAGCCGC TACAGCACAC CAATTGACAT ATGGAGTTTT 
GGCTGCATCC TTGCAGAACT TTTAACAGGA CAGCCTCTCT TCCCTGGAGA GGATGAAGGA 
GACCAGTTGG CCTGCATGAT GGAGCTTCTA GGGATGCCAC CACCAAAACT TCTGGAGCAA 
TCCAAACGTG CCAAGTACTT TATTAATTCC AAGGGCATAC CCCGCTACTG CTCTGTGACT 
ACCCAGGCAG ATGGGAGGGT TGTGCTTGTG GGGGGTCGCT CACGTAGGGG TAAAAAGCGG 
GGTCCCCCAG GCAGCAAAGA CTGGGGGACA GCACTGAAAG GGTGTGATGA CTACTTGTTT 
ATAGAGTTCT TGAAAAGGTG TCTTCACTGG GACCCCTCTG CCCGCTTGAC CCCAGCTCAA 
GCATTAAGAC ACCCTTGGAT TAGCAAGTCT GTCCCCAGAC CTCTCACCAC CATAGACAAG 
GTGTCAGGGA AACGGGTAGT TAATCCTGCA AGTGCTTTCC AGGGATTGGG TTCTAAGCTG 
CCTCCAGTTG TTGGAATAGC CAATAAGCTT AAAGCTAACT TAATGTCAGA AACCAATGGT 
AGTATACCCC TATGCAGTGT ATTGCCAAAA CTGATTAGCT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011508363.1
CDS	108..1769
Translation	MMIDETKCPPCSNVLCNPSEPPPPRRLNMTTEQFTGDHTQHFLDGGEMKVEQLFQEFGNRKSNTIQSDGISDSEKCSPTVSQGKSSDCLNTVKSNSSSKAPKVVPLTPEQALKQYKHHLTAYEKLEIINYPEIYFVGPNAKKRHGVIGGPNNGGYDDADGAYIHVPRDHLAYRYEVLKIIGKGSFGQVARVYDHKLRQYVALKMVRNEKRFHRQAAEEIRILEHLKKQDKTGSMNVIHMLESFTFRNHVCMAFELLSIDLYELIKKNKFQGFSVQLVRKFAQSILQSLDALHKNKIIHCDLKPENILLKHHGRSSTKVIDFGSSCFEYQKLYTYIQSRFYRAPEIILGSRYSTPIDIWSFGCILAELLTGQPLFPGEDEGDQLACMMELLGMPPPKLLEQSKRAKYFINSKGIPRYCSVTTQADGRVVLVGGRSRRGKKRGPPGSKDWGTALKGCDDYLFIEFLKRCLHWDPSARLTPAQALRHPWISKSVPRPLTTIDKVSGKRVVNPASAFQGLGSKLPPVVGIANKLKANLMSETNGSIPLCSVLPKLIS

Target ORF information:

RefSeq Version	XM_011510061.2
Organism	Homo sapiens(human)
Definition	Homo sapiens dual specificity tyrosine phosphorylation regulated kinase 3 (DYRK3), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011510061.2

ORF Insert Sequence:

ATGATGATAG ATGAAACCAA ATGTCCCCCC TGTTCAAATG TACTCTGCAA TCCTTCTGAA 
CCACCTCCAC CCAGAAGACT AAATATGACC ACTGAGCAGT TTACAGGAGA TCATACTCAG 
CACTTTTTGG ATGGAGGTGA GATGAAGGTA GAACAGCTGT TTCAAGAATT TGGCAACAGA 
AAATCCAATA CTATTCAGTC AGATGGCATC AGTGACTCTG AAAAATGCTC TCCTACTGTT 
TCTCAGGGTA AAAGTTCAGA TTGCTTGAAT ACAGTAAAAT CCAACAGTTC ATCCAAGGCA 
CCCAAAGTGG TGCCTCTGAC TCCAGAACAA GCCCTGAAGC AATATAAACA CCACCTCACT 
GCCTATGAGA AACTGGAAAT AATTAATTAT CCAGAAATTT ACTTTGTAGG TCCAAATGCC 
AAGAAAAGAC ATGGAGTTAT TGGTGGTCCC AATAATGGAG GGTATGATGA TGCAGATGGG 
GCCTATATTC ATGTACCTCG AGACCATCTA GCTTATCGAT ATGAGGTGCT GAAAATTATT 
GGCAAGGGGA GTTTTGGGCA GGTGGCCAGG GTCTATGATC ACAAACTTCG ACAGTACGTG 
GCCCTAAAAA TGGTGCGCAA TGAGAAGCGC TTTCATCGTC AAGCAGCTGA GGAGATCCGG 
ATTTTGGAGC ATCTTAAGAA ACAGGATAAA ACTGGTAGTA TGAACGTTAT CCACATGCTG 
GAAAGTTTCA CATTCCGGAA CCATGTTTGC ATGGCCTTTG AATTGCTGAG CATAGACCTT 
TATGAGCTGA TTAAAAAAAA TAAGTTTCAG GGTTTTAGCG TCCAGTTGGT ACGCAAGTTT 
GCCCAGTCCA TCTTGCAATC TTTGGATGCC CTCCACAAAA ATAAGATTAT TCACTGCGAT 
CTGAAGCCAG AAAACATTCT CCTGAAACAC CACGGGCGCA GTTCAACCAA GGTCATTGAC 
TTTGGGTCCA GCTGTTTCGA GTACCAGAAG CTCTACACAT ATATCCAGTC TCGGTTCTAC 
AGAGCTCCAG AAATCATCTT AGGAAGCCGC TACAGCACAC CAATTGACAT ATGGAGTTTT 
GGCTGCATCC TTGCAGAACT TTTAACAGGA CAGCCTCTCT TCCCTGGAGA GGATGAAGGA 
GACCAGTTGG CCTGCATGAT GGAGCTTCTA GGGATGCCAC CACCAAAACT TCTGGAGCAA 
TCCAAACGTG CCAAGTACTT TATTAATTCC AAGGGCATAC CCCGCTACTG CTCTGTGACT 
ACCCAGGCAG ATGGGAGGGT TGTGCTTGTG GGGGGTCGCT CACGTAGGGG TAAAAAGCGG 
GGTCCCCCAG GCAGCAAAGA CTGGGGGACA GCACTGAAAG GGTGTGATGA CTACTTGTTT 
ATAGAGTTCT TGAAAAGGTG TCTTCACTGG GACCCCTCTG CCCGCTTGAC CCCAGCTCAA 
GCATTAAGAC ACCCTTGGAT TAGCAAGTCT GTCCCCAGAC CTCTCACCAC CATAGACAAG 
GTGTCAGGGA AACGGGTAGT TAATCCTGCA AGTGCTTTCC AGGGATTGGG TTCTAAGCTG 
CCTCCAGTTG TTGGAATAGC CAATAAGCTT AAAGCTAACT TAATGTCAGA AACCAATGGT 
AGTATACCCC TATGCAGTGT ATTGCCAAAA CTGATTAGCT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Dual specificity kinase DYRK3 couples stress granule condensation/dissolution to mTORC1 signaling.
Cell152(4)791-805(2013 Feb)
Wippich F,Bodenmiller B,Trajkovska MG,Wanka S,Aebersold R,Pelkmans L

Invasion of Cryptococcus neoformans into human brain microvascular endothelial cells is mediated through the lipid rafts-endocytic pathway via the dual specificity tyrosine phosphorylation-regulated kinase 3 (DYRK3).
The Journal of biological chemistry286(40)34761-9(2011 Oct)
Huang SH,Long M,Wu CH,Kwon-Chung KJ,Chang YC,Chi F,Lee S,Jong A

DYRK1A and DYRK3 promote cell survival through phosphorylation and activation of SIRT1.
The Journal of biological chemistry285(17)13223-32(2010 Apr)
Guo X,Williams JG,Schug TT,Li X

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DYRK3 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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