NIFK cDNA ORF clone, Homo sapiens(human)

The cell proliferation antigen Ki-67 organises heterochromatin.
Sobecki M, Mrouj K, Camasses A, Parisis N, Nicolas E, Ll?res D, Gerbe F, Prieto S, Krasinska L, David A, Eguren M, Birling MC, Urbach S, Hem S, D?jardin J, Malumbres M, Jay P, Dulic V, Lafontaine DLj, Feil R, Fisher D
eLife5e13722(2016 Mar)

The nucleolar protein NIFK promotes cancer progression via CK1?/?-catenin in metastasis and Ki-67-dependent cell proliferation.
Lin TC, Su CY, Wu PY, Lai TC, Pan WA, Jan YH, Chang YC, Yeh CT, Chen CL, Ger LP, Chang HT, Yang CJ, Huang MS, Liu YP, Lin YF, Shyy JY, Tsai MD, Hsiao M
eLife5(2016 Mar)

The RNA recognition motif of NIFK is required for rRNA maturation during cell cycle progression.
Pan WA, Tsai HY, Wang SC, Hsiao M, Wu PY, Tsai MD
RNA biology12(3)255-67(2015)

Insights into RNA biology from an atlas of mammalian mRNA-binding proteins.
Castello A, Fischer B, Eichelbaum K, Horos R, Beckmann BM, Strein C, Davey NE, Humphreys DT, Preiss T, Steinmetz LM, Krijgsveld J, Hentze MW
Cell149(6)1393-406(2012 Jun)

The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.
Baltz AG, Munschauer M, Schwanh?usser B, Vasile A, Murakawa Y, Schueler M, Youngs N, Penfold-Brown D, Drew K, Milek M, Wyler E, Bonneau R, Selbach M, Dieterich C, Landthaler M
Molecular cell46(5)674-90(2012 Jun)

NIFK is required for lung cancer progression via the RUNX1-dependent CK1alpha repression, which activates TCF4/beta-catenin signaling in metastasis and the Ki-67-dependent regulation in cell proliferation.
Title: The nucleolar protein NIFK promotes cancer progression via CK1?/?-catenin in metastasis and Ki-67-dependent cell proliferation.

The RNA recognition motif of NIFK is required for rRNA maturation during cell cycle progression.
Title: The RNA recognition motif of NIFK is required for rRNA maturation during cell cycle progression.

Potential encounter complexes of the Ki67FHA receptor and hNIFK peptide are misregistered states of the beta-sheet.
Title: Direct observations of shifts in the ?-sheet register of a protein-peptide complex using explicit solvent simulations.

Better basal gene expression was observed by co-cultured respiratory epithelial cells compared to dispase dissociated cells.
Title: Human nasal turbinates as a viable source of respiratory epithelial cells using co-culture system versus dispase-dissociation technique.

nmr analysis of the solution structure of the FHA domain of human Ki67 and mapping of the binding surface for NIFK binding
Title: Structure of human Ki67 FHA domain and its binding to a phosphoprotein fragment from hNIFK reveal unique recognition sites and new views to the structural basis of FHA domain functions.