SOAT2 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	SOAT2
Entrez Gene ID	8435
Full Name	sterol O-acyltransferase 2
Synonyms	ACACT2,ACAT2,ARGP2
General protein information	Preferred Names sterol O-acyltransferase 2 Names sterol O-acyltransferase 2 ACAT-2 acyl Co-A: cholesterol acyltransferase 2 acyl coenzyme A:cholesterol acyltransferase 2 acyl-CoA:cholesterol acyltransferase 2 cholesterol acyltransferase 2
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 12 Map Location: 12q13.13
Summary	This gene is a member of a small family of acyl coenzyme A:cholesterol acyltransferases. The gene encodes a membrane-bound enzyme localized in the endoplasmic reticulum that produces intracellular cholesterol esters from long-chain fatty acyl CoA and cholesterol. The cholesterol esters are then stored as cytoplasmic lipid droplets inside the cell. The enzyme is implicated in cholesterol absorption in the intestine and in the assembly and secretion of apolipoprotein B-containing lipoproteins such as very low density lipoprotein (VLDL). Several alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq, Jul 2008].
Disorder MIM:	601311

mRNA and Protein(s)

mRNA	Protein	Name
NM_003578.3	NP_003569.1	sterol O-acyltransferase 2
NM_003578.4	NP_003569.1	sterol O-acyltransferase 2
XM_011538851.2	XP_011537153.1	sterol O-acyltransferase 2 isoform X3
XM_011538849.2	XP_011537151.1	sterol O-acyltransferase 2 isoform X1
XM_011538850.2	XP_011537152.1	sterol O-acyltransferase 2 isoform X2

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	SOAT2	XP_005637467.1
Bos taurus (cattle)	SOAT2	NP_001095446.1
Rattus norvegicus (Norway rat)	Soat2	NP_714950.2
Homo sapiens (human)	SOAT2	NP_003569.1
Pan troglodytes (chimpanzee)	SOAT2	XP_001141788.1
Mus musculus (house mouse)	Soat2	NP_666176.1
	SOAT2	XP_001102393.1
Xenopus tropicalis (tropical clawed frog)	LOC101730739	XP_004912012.1
Xenopus tropicalis (tropical clawed frog)	soat2	NP_001135718.1

Gene Ontology
Bibliography

Related articles in PubMed

Cholesterol and fatty acids regulate cysteine ubiquitylation of ACAT2 through competitive oxidation.
Wang YJ, Bian Y, Luo J, Lu M, Xiong Y, Guo SY, Yin HY, Lin X, Li Q, Chang CCY, Chang TY, Li BL, Song BL
Nature cell biology19(7)808-819(2017 Jul)

The ACAT2 expression of human leukocytes is responsible for the excretion of lipoproteins containing cholesteryl/steryl esters.
Guo D, Zhang X, Li Q, Qian L, Xu J, Lu M, Hu X, Zhu M, Chang CC, Song B, Chang T, Xiong Y, Li B
Acta biochimica et biophysica Sinica48(11)990-997(2016 Nov)

Prognostic significance of two lipid metabolism enzymes, HADHA and ACAT2, in clear cell renal cell carcinoma.
Zhao Z, Lu J, Han L, Wang X, Man Q, Liu S
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine37(6)8121-30(2016 Jun)

Functional characterization of two single nucleotide polymorphisms of acyl-coenzyme A:cholesterol acyltransferase 2.
He X, Leow KY, Yang H, Heng CK
Gene566(2)236-41(2015 Jul)

TG-interacting factor 1 acts as a transcriptional repressor of sterol O-acyltransferase 2.
Pramfalk C, Melhuish TA, Wotton D, Jiang ZY, Eriksson M, Parini P
Journal of lipid research55(4)709-17(2014 Apr)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

TG-interacting factor 1 (Tgif1) is an important repressor of SOAT2 gene expression.
Title: TG-interacting factor 1 acts as a transcriptional repressor of sterol O-acyltransferase 2.

CDX2, a known positive regulator of hepatocyte differentiation, was regulated by miR-181d and directly activated SOAT2 gene expression.
Title: Thyroid hormone negatively regulates CDX2 and SOAT2 mRNA expression via induction of miRNA-181d in hepatic cells.

Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
Title: Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.

Observational study of gene-disease association. (HuGE Navigator)
Title: Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.

Observational study of gene-disease association. (HuGE Navigator)
Title: Candidate genetic analysis of plasma high-density lipoprotein-cholesterol and severity of coronary atherosclerosis.

The following SOAT2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the SOAT2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu00927	NM_003578.4 Latest version!	Homo sapiens sterol O-acyltransferase 2 (SOAT2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$219.50-$307.30 $439.00
OHu61767	XM_011538849.2 Latest version!	Homo sapiens sterol O-acyltransferase 2 (SOAT2), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
OHu61768	XM_011538850.2 Latest version!	Homo sapiens sterol O-acyltransferase 2 (SOAT2), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
OHu61769	XM_011538851.2 Latest version!	Homo sapiens sterol O-acyltransferase 2 (SOAT2), transcript variant X5, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
View Old Accession Versions >>
OHu00927	NM_003578.3	Homo sapiens sterol O-acyltransferase 2 (SOAT2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$219.50-$307.30 $439.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

SOAT2 ( NM_003578.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_003569.1 Homo sapiens sterol O-acyltransferase 2 (SOAT2), mRNA.

Price & Availability↑

CloneID	OHu00927
Clone ID Related Accession (Same CDS sequence)	NM_003578.3 , NM_003578.4
Accession Version	NM_003578.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1569bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-01
Organism	Homo sapiens(human)
Product	sterol O-acyltransferase 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC073573.27 and AF059203.1. On Feb 16, 2007 this sequence version replaced NM_003578.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF059203.1, BC096090.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2144835, SAMEA2145122 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: full length.

ATGGAGCCAG GCGGGGCCCG TCTGCGTCTG CAGAGGACAG AAGGGCTGGG AGGGGAGCGG 
GAGCGCCAAC CCTGTGGAGA TGGAAACACT GAGACGCACA GAGCCCCGGA CTTGGTACAA 
TGGACCCGAC ACATGGAGGC TGTGAAGGCA CAATTGCTGG AGCAAGCGCA GGGACAACTG 
AGGGAGCTGC TGGATCGGGC CATGCGGGAG GCTATACAAT CCTACCCATC ACAAGACAAA 
CCTCTGCCCC CACCTCCCCC AGGTTCCTTG AGCAGGACCC AGGAGCCATC CCTGGGGAAA 
CAGAAAGTTT TCATCATCCG CAAGTCCCTG CTTGATGAGC TGATGGAGGT GCAGCATTTC 
CGCACCATCT ACCACATGTT CATCGCTGGC CTGTGTGTCT TCATCATCAG CACCCTGGCC 
ATCGACTTCA TTGATGAGGG CAGGCTGCTG CTGGAGTTTG ACCTACTGAT CTTCAGCTTC 
GGACAGCTGC CATTGGCGCT GGTGACCTGG GTGCCCATGT TTCTGTCCAC CCTGTTGGCG 
CCGTACCAGG CCCTACGGCT GTGGGCCAGG GGCACCTGGA CGCAGGCGAC GGGCCTGGGC 
TGTGCGCTGC TAGCCGCCCA CGCCGTGGTG CTCTGCGCGC TGCCGGTCCA CGTGGCCGTG 
GAGCATCAGC TCCCGCCGGC CTCCCGTTGT GTCCTGGTCT TCGAGCAGGT TAGGTTCCTG 
ATGAAAAGCT ACTCCTTCCT GAGAGAGGCT GTGCCTGGGA CCCTTCGTGC CAGACGAGGT 
GAGGGGATCC AGGCCCCCAG TTTCTCCAGC TACCTCTACT TCCTCTTCTG CCCAACACTC 
ATCTACAGGG AGACTTACCC TAGGACGCCC TATGTCAGGT GGAATTATGT GGCCAAGAAC 
TTTGCCCAGG CCCTGGGATG TGTGCTCTAT GCCTGCTTCA TCCTGGGCCG CCTCTGTGTT 
CCTGTCTTTG CCAACATGAG CCGAGAGCCC TTCAGCACCC GTGCCCTGGT GCTCTCTATC 
CTGCATGCCA CGTTGCCAGG CATCTTCATG CTGCTGCTCA TCTTCTTTGC CTTCCTCCAT 
TGCTGGCTCA ACGCCTTTGC CGAGATGCTA CGATTTGGAG ACAGGATGTT CTACCGGGAC 
TGGTGGAACT CAACGTCCTT CTCCAACTAC TACCGCACTT GGAACGTGGT GGTCCATGAC 
TGGCTGTACA GCTACGTGTA TCAGGATGGG CTGCGGCTCC TTGGTGCCCG GGCCCGAGGG 
GTAGCCATGC TGGGTGTGTT CCTGGTCTCC GCAGTGGCCC ATGAGTATAT CTTCTGCTTC 
GTCCTGGGGT TCTTCTATCC CGTCATGCTG ATACTCTTCC TTGTCATTGG AGGAATGTTG 
AACTTCATGA TGCATGACCA GCGCACCGGC CCGGCATGGA ACGTGCTGAT GTGGACCATG 
CTGTTTCTAG GCCAGGGAAT CCAGGTCAGC CTGTACTGCC AGGAGTGGTA CGCACGGCGG 
CACTGCCCCT TACCCCAGGC AACTTTCTGG GGGCTGGTGA CACCTCGATC TTGGTCCTGC 
CATACCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_003569.1
CDS	89..1657
Translation	MEPGGARLRLQRTEGLGGERERQPCGDGNTETHRAPDLVQWTRHMEAVKAQLLEQAQGQLRELLDRAMREAIQSYPSQDKPLPPPPPGSLSRTQEPSLGKQKVFIIRKSLLDELMEVQHFRTIYHMFIAGLCVFIISTLAIDFIDEGRLLLEFDLLIFSFGQLPLALVTWVPMFLSTLLAPYQALRLWARGTWTQATGLGCALLAAHAVVLCALPVHVAVEHQLPPASRCVLVFEQVRFLMKSYSFLREAVPGTLRARRGEGIQAPSFSSYLYFLFCPTLIYRETYPRTPYVRWNYVAKNFAQALGCVLYACFILGRLCVPVFANMSREPFSTRALVLSILHATLPGIFMLLLIFFAFLHCWLNAFAEMLRFGDRMFYRDWWNSTSFSNYYRTWNVVVHDWLYSYVYQDGLRLLGARARGVAMLGVFLVSAVAHEYIFCFVLGFFYPVMLILFLVIGGMLNFMMHDQRTGPAWNVLMWTMLFLGQGIQVSLYCQEWYARRHCPLPQATFWGLVTPRSWSCHT

Target ORF information:

RefSeq Version	NM_003578.3
Organism	Homo sapiens(human)
Definition	Homo sapiens sterol O-acyltransferase 2 (SOAT2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_003578.3

ORF Insert Sequence:

ATGGAGCCAG GCGGGGCCCG TCTGCGTCTG CAGAGGACAG AAGGGCTGGG AGGGGAGCGG 
GAGCGCCAAC CCTGTGGAGA TGGAAACACT GAGACGCACA GAGCCCCGGA CTTGGTACAA 
TGGACCCGAC ACATGGAGGC TGTGAAGGCA CAATTGCTGG AGCAAGCGCA GGGACAACTG 
AGGGAGCTGC TGGATCGGGC CATGCGGGAG GCTATACAAT CCTACCCATC ACAAGACAAA 
CCTCTGCCCC CACCTCCCCC AGGTTCCTTG AGCAGGACCC AGGAGCCATC CCTGGGGAAA 
CAGAAAGTTT TCATCATCCG CAAGTCCCTG CTTGATGAGC TGATGGAGGT GCAGCATTTC 
CGCACCATCT ACCACATGTT CATCGCTGGC CTGTGTGTCT TCATCATCAG CACCCTGGCC 
ATCGACTTCA TTGATGAGGG CAGGCTGCTG CTGGAGTTTG ACCTACTGAT CTTCAGCTTC 
GGACAGCTGC CATTGGCGCT GGTGACCTGG GTGCCCATGT TTCTGTCCAC CCTGTTGGCG 
CCGTACCAGG CCCTACGGCT GTGGGCCAGG GGCACCTGGA CGCAGGCGAC GGGCCTGGGC 
TGTGCGCTGC TAGCCGCCCA CGCCGTGGTG CTCTGCGCGC TGCCGGTCCA CGTGGCCGTG 
GAGCATCAGC TCCCGCCGGC CTCCCGTTGT GTCCTGGTCT TCGAGCAGGT TAGGTTCCTG 
ATGAAAAGCT ACTCCTTCCT GAGAGAGGCT GTGCCTGGGA CCCTTCGTGC CAGACGAGGT 
GAGGGGATCC AGGCCCCCAG TTTCTCCAGC TACCTCTACT TCCTCTTCTG CCCAACACTC 
ATCTACAGGG AGACTTACCC TAGGACGCCC TATGTCAGGT GGAATTATGT GGCCAAGAAC 
TTTGCCCAGG CCCTGGGATG TGTGCTCTAT GCCTGCTTCA TCCTGGGCCG CCTCTGTGTT 
CCTGTCTTTG CCAACATGAG CCGAGAGCCC TTCAGCACCC GTGCCCTGGT GCTCTCTATC 
CTGCATGCCA CGTTGCCAGG CATCTTCATG CTGCTGCTCA TCTTCTTTGC CTTCCTCCAT 
TGCTGGCTCA ACGCCTTTGC CGAGATGCTA CGATTTGGAG ACAGGATGTT CTACCGGGAC 
TGGTGGAACT CAACGTCCTT CTCCAACTAC TACCGCACTT GGAACGTGGT GGTCCATGAC 
TGGCTGTACA GCTACGTGTA TCAGGATGGG CTGCGGCTCC TTGGTGCCCG GGCCCGAGGG 
GTAGCCATGC TGGGTGTGTT CCTGGTCTCC GCAGTGGCCC ATGAGTATAT CTTCTGCTTC 
GTCCTGGGGT TCTTCTATCC CGTCATGCTG ATACTCTTCC TTGTCATTGG AGGAATGTTG 
AACTTCATGA TGCATGACCA GCGCACCGGC CCGGCATGGA ACGTGCTGAT GTGGACCATG 
CTGTTTCTAG GCCAGGGAAT CCAGGTCAGC CTGTACTGCC AGGAGTGGTA CGCACGGCGG 
CACTGCCCCT TACCCCAGGC AACTTTCTGG GGGCTGGTGA CACCTCGATC TTGGTCCTGC 
CATACCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SOAT2 ( NM_003578.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_003569.1 Homo sapiens sterol O-acyltransferase 2 (SOAT2), mRNA.

Price & Availability↑

CloneID	OHu00927
Clone ID Related Accession (Same CDS sequence)	NM_003578.3 , NM_003578.4
Accession Version	NM_003578.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1569bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-02
Organism	Homo sapiens(human)
Product	sterol O-acyltransferase 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC073573.27 and AF059203.1. On Nov 22, 2018 this sequence version replaced NM_003578.3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF059203.1, BC096090.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2144835, SAMEA2145122 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000301466.8/ ENSP00000301466.3 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGAGCCAG GCGGGGCCCG TCTGCGTCTG CAGAGGACAG AAGGGCTGGG AGGGGAGCGG 
GAGCGCCAAC CCTGTGGAGA TGGAAACACT GAGACGCACA GAGCCCCGGA CTTGGTACAA 
TGGACCCGAC ACATGGAGGC TGTGAAGGCA CAATTGCTGG AGCAAGCGCA GGGACAACTG 
AGGGAGCTGC TGGATCGGGC CATGCGGGAG GCTATACAAT CCTACCCATC ACAAGACAAA 
CCTCTGCCCC CACCTCCCCC AGGTTCCTTG AGCAGGACCC AGGAGCCATC CCTGGGGAAA 
CAGAAAGTTT TCATCATCCG CAAGTCCCTG CTTGATGAGC TGATGGAGGT GCAGCATTTC 
CGCACCATCT ACCACATGTT CATCGCTGGC CTGTGTGTCT TCATCATCAG CACCCTGGCC 
ATCGACTTCA TTGATGAGGG CAGGCTGCTG CTGGAGTTTG ACCTACTGAT CTTCAGCTTC 
GGACAGCTGC CATTGGCGCT GGTGACCTGG GTGCCCATGT TTCTGTCCAC CCTGTTGGCG 
CCGTACCAGG CCCTACGGCT GTGGGCCAGG GGCACCTGGA CGCAGGCGAC GGGCCTGGGC 
TGTGCGCTGC TAGCCGCCCA CGCCGTGGTG CTCTGCGCGC TGCCGGTCCA CGTGGCCGTG 
GAGCATCAGC TCCCGCCGGC CTCCCGTTGT GTCCTGGTCT TCGAGCAGGT TAGGTTCCTG 
ATGAAAAGCT ACTCCTTCCT GAGAGAGGCT GTGCCTGGGA CCCTTCGTGC CAGACGAGGT 
GAGGGGATCC AGGCCCCCAG TTTCTCCAGC TACCTCTACT TCCTCTTCTG CCCAACACTC 
ATCTACAGGG AGACTTACCC TAGGACGCCC TATGTCAGGT GGAATTATGT GGCCAAGAAC 
TTTGCCCAGG CCCTGGGATG TGTGCTCTAT GCCTGCTTCA TCCTGGGCCG CCTCTGTGTT 
CCTGTCTTTG CCAACATGAG CCGAGAGCCC TTCAGCACCC GTGCCCTGGT GCTCTCTATC 
CTGCATGCCA CGTTGCCAGG CATCTTCATG CTGCTGCTCA TCTTCTTTGC CTTCCTCCAT 
TGCTGGCTCA ACGCCTTTGC CGAGATGCTA CGATTTGGAG ACAGGATGTT CTACCGGGAC 
TGGTGGAACT CAACGTCCTT CTCCAACTAC TACCGCACTT GGAACGTGGT GGTCCATGAC 
TGGCTGTACA GCTACGTGTA TCAGGATGGG CTGCGGCTCC TTGGTGCCCG GGCCCGAGGG 
GTAGCCATGC TGGGTGTGTT CCTGGTCTCC GCAGTGGCCC ATGAGTATAT CTTCTGCTTC 
GTCCTGGGGT TCTTCTATCC CGTCATGCTG ATACTCTTCC TTGTCATTGG AGGAATGTTG 
AACTTCATGA TGCATGACCA GCGCACCGGC CCGGCATGGA ACGTGCTGAT GTGGACCATG 
CTGTTTCTAG GCCAGGGAAT CCAGGTCAGC CTGTACTGCC AGGAGTGGTA CGCACGGCGG 
CACTGCCCCT TACCCCAGGC AACTTTCTGG GGGCTGGTGA CACCTCGATC TTGGTCCTGC 
CATACCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_003569.1
CDS	93..1661
Translation	MEPGGARLRLQRTEGLGGERERQPCGDGNTETHRAPDLVQWTRHMEAVKAQLLEQAQGQLRELLDRAMREAIQSYPSQDKPLPPPPPGSLSRTQEPSLGKQKVFIIRKSLLDELMEVQHFRTIYHMFIAGLCVFIISTLAIDFIDEGRLLLEFDLLIFSFGQLPLALVTWVPMFLSTLLAPYQALRLWARGTWTQATGLGCALLAAHAVVLCALPVHVAVEHQLPPASRCVLVFEQVRFLMKSYSFLREAVPGTLRARRGEGIQAPSFSSYLYFLFCPTLIYRETYPRTPYVRWNYVAKNFAQALGCVLYACFILGRLCVPVFANMSREPFSTRALVLSILHATLPGIFMLLLIFFAFLHCWLNAFAEMLRFGDRMFYRDWWNSTSFSNYYRTWNVVVHDWLYSYVYQDGLRLLGARARGVAMLGVFLVSAVAHEYIFCFVLGFFYPVMLILFLVIGGMLNFMMHDQRTGPAWNVLMWTMLFLGQGIQVSLYCQEWYARRHCPLPQATFWGLVTPRSWSCHT

Target ORF information:

RefSeq Version	NM_003578.4
Organism	Homo sapiens(human)
Definition	Homo sapiens sterol O-acyltransferase 2 (SOAT2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_003578.4

ORF Insert Sequence:

ATGGAGCCAG GCGGGGCCCG TCTGCGTCTG CAGAGGACAG AAGGGCTGGG AGGGGAGCGG 
GAGCGCCAAC CCTGTGGAGA TGGAAACACT GAGACGCACA GAGCCCCGGA CTTGGTACAA 
TGGACCCGAC ACATGGAGGC TGTGAAGGCA CAATTGCTGG AGCAAGCGCA GGGACAACTG 
AGGGAGCTGC TGGATCGGGC CATGCGGGAG GCTATACAAT CCTACCCATC ACAAGACAAA 
CCTCTGCCCC CACCTCCCCC AGGTTCCTTG AGCAGGACCC AGGAGCCATC CCTGGGGAAA 
CAGAAAGTTT TCATCATCCG CAAGTCCCTG CTTGATGAGC TGATGGAGGT GCAGCATTTC 
CGCACCATCT ACCACATGTT CATCGCTGGC CTGTGTGTCT TCATCATCAG CACCCTGGCC 
ATCGACTTCA TTGATGAGGG CAGGCTGCTG CTGGAGTTTG ACCTACTGAT CTTCAGCTTC 
GGACAGCTGC CATTGGCGCT GGTGACCTGG GTGCCCATGT TTCTGTCCAC CCTGTTGGCG 
CCGTACCAGG CCCTACGGCT GTGGGCCAGG GGCACCTGGA CGCAGGCGAC GGGCCTGGGC 
TGTGCGCTGC TAGCCGCCCA CGCCGTGGTG CTCTGCGCGC TGCCGGTCCA CGTGGCCGTG 
GAGCATCAGC TCCCGCCGGC CTCCCGTTGT GTCCTGGTCT TCGAGCAGGT TAGGTTCCTG 
ATGAAAAGCT ACTCCTTCCT GAGAGAGGCT GTGCCTGGGA CCCTTCGTGC CAGACGAGGT 
GAGGGGATCC AGGCCCCCAG TTTCTCCAGC TACCTCTACT TCCTCTTCTG CCCAACACTC 
ATCTACAGGG AGACTTACCC TAGGACGCCC TATGTCAGGT GGAATTATGT GGCCAAGAAC 
TTTGCCCAGG CCCTGGGATG TGTGCTCTAT GCCTGCTTCA TCCTGGGCCG CCTCTGTGTT 
CCTGTCTTTG CCAACATGAG CCGAGAGCCC TTCAGCACCC GTGCCCTGGT GCTCTCTATC 
CTGCATGCCA CGTTGCCAGG CATCTTCATG CTGCTGCTCA TCTTCTTTGC CTTCCTCCAT 
TGCTGGCTCA ACGCCTTTGC CGAGATGCTA CGATTTGGAG ACAGGATGTT CTACCGGGAC 
TGGTGGAACT CAACGTCCTT CTCCAACTAC TACCGCACTT GGAACGTGGT GGTCCATGAC 
TGGCTGTACA GCTACGTGTA TCAGGATGGG CTGCGGCTCC TTGGTGCCCG GGCCCGAGGG 
GTAGCCATGC TGGGTGTGTT CCTGGTCTCC GCAGTGGCCC ATGAGTATAT CTTCTGCTTC 
GTCCTGGGGT TCTTCTATCC CGTCATGCTG ATACTCTTCC TTGTCATTGG AGGAATGTTG 
AACTTCATGA TGCATGACCA GCGCACCGGC CCGGCATGGA ACGTGCTGAT GTGGACCATG 
CTGTTTCTAG GCCAGGGAAT CCAGGTCAGC CTGTACTGCC AGGAGTGGTA CGCACGGCGG 
CACTGCCCCT TACCCCAGGC AACTTTCTGG GGGCTGGTGA CACCTCGATC TTGGTCCTGC 
CATACCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SOAT2 ( XM_011538849.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011537151.1 Homo sapiens sterol O-acyltransferase 2 (SOAT2), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu61767
Clone ID Related Accession (Same CDS sequence)	XM_011538849.2
Accession Version	XM_011538849.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1509bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	sterol O-acyltransferase 2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000012.12) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011538849.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAGCCAG GCGGGGCCCG TCTGCGTCTG CAGAGGACAG AAGGGCTGGG AGGGGAGCGG 
GAGCGCCAAC CCTGTGGAGA TGGAAACACT GAGACGCACA GAGCCCCGGA CTTGGTACAA 
TGGACCCGAC ACATGGAGGC TGTGAAGGCA CAATTGCTGG AGCAAGCGCA GGGACAACTG 
AGGGAGCTGC TGGATCGGGC CATGCGGGAG GCTATACAAT CCTACCCATC ACAAGACAAA 
CCTCTGCCCC CACCTCCCCC AGGTTCCTTG AGCAGTGAGC TGATGGAGGT GCAGCATTTC 
CGCACCATCT ACCACATGTT CATCGCTGGC CTGTGTGTCT TCATCATCAG CACCCTGGCC 
ATCGACTTCA TTGATGAGGG CAGGCTGCTG CTGGAGTTTG ACCTACTGAT CTTCAGCTTC 
GGACAGCTGC CATTGGCGCT GGTGACCTGG GTGCCCATGT TTCTGTCCAC CCTGTTGGCG 
CCGTACCAGG CCCTACGGCT GTGGGCCAGG GGCACCTGGA CGCAGGCGAC GGGCCTGGGC 
TGTGCGCTGC TAGCCGCCCA CGCCGTGGTG CTCTGCGCGC TGCCGGTCCA CGTGGCCGTG 
GAGCATCAGC TCCCGCCGGC CTCCCGTTGT GTCCTGGTCT TCGAGCAGGT TAGGTTCCTG 
ATGAAAAGCT ACTCCTTCCT GAGAGAGGCT GTGCCTGGGA CCCTTCGTGC CAGACGAGGT 
GAGGGGATCC AGGCCCCCAG TTTCTCCAGC TACCTCTACT TCCTCTTCTG CCCAACACTC 
ATCTACAGGG AGACTTACCC TAGGACGCCC TATGTCAGGT GGAATTATGT GGCCAAGAAC 
TTTGCCCAGG CCCTGGGATG TGTGCTCTAT GCCTGCTTCA TCCTGGGCCG CCTCTGTGTT 
CCTGTCTTTG CCAACATGAG CCGAGAGCCC TTCAGCACCC GTGCCCTGGT GCTCTCTATC 
CTGCATGCCA CGTTGCCAGG CATCTTCATG CTGCTGCTCA TCTTCTTTGC CTTCCTCCAT 
TGCTGGCTCA ACGCCTTTGC CGAGATGCTA CGATTTGGAG ACAGGATGTT CTACCGGGAC 
TGGTGGAACT CAACGTCCTT CTCCAACTAC TACCGCACTT GGAACGTGGT GGTCCATGAC 
TGGCTGTACA GCTACGTGTA TCAGGATGGG CTGCGGCTCC TTGGTGCCCG GGCCCGAGGG 
GTAGCCATGC TGGGTGTGTT CCTGGTCTCC GCAGTGGCCC ATGAGTATAT CTTCTGCTTC 
GTCCTGGGGT TCTTCTATCC CGTCATGCTG ATACTCTTCC TTGTCATTGG AGGAATGTTG 
AACTTCATGA TGCATGACCA GCGCACCGGC CCGGCATGGA ACGTGCTGAT GTGGACCATG 
CTGTTTCTAG GCCAGGGAAT CCAGGTCAGC CTGTACTGCC AGGAGTGGTA CGCACGGCGG 
CACTGCCCCT TACCCCAGGC AACTTTCTGG GGGCTGGTGA CACCTCGATC TTGGTCCTGC 
CATACCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011537151.1
CDS	1142..2650
Translation	MEPGGARLRLQRTEGLGGERERQPCGDGNTETHRAPDLVQWTRHMEAVKAQLLEQAQGQLRELLDRAMREAIQSYPSQDKPLPPPPPGSLSSELMEVQHFRTIYHMFIAGLCVFIISTLAIDFIDEGRLLLEFDLLIFSFGQLPLALVTWVPMFLSTLLAPYQALRLWARGTWTQATGLGCALLAAHAVVLCALPVHVAVEHQLPPASRCVLVFEQVRFLMKSYSFLREAVPGTLRARRGEGIQAPSFSSYLYFLFCPTLIYRETYPRTPYVRWNYVAKNFAQALGCVLYACFILGRLCVPVFANMSREPFSTRALVLSILHATLPGIFMLLLIFFAFLHCWLNAFAEMLRFGDRMFYRDWWNSTSFSNYYRTWNVVVHDWLYSYVYQDGLRLLGARARGVAMLGVFLVSAVAHEYIFCFVLGFFYPVMLILFLVIGGMLNFMMHDQRTGPAWNVLMWTMLFLGQGIQVSLYCQEWYARRHCPLPQATFWGLVTPRSWSCHT

Target ORF information:

RefSeq Version	XM_011538849.2
Organism	Homo sapiens(human)
Definition	Homo sapiens sterol O-acyltransferase 2 (SOAT2), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011538849.2

ORF Insert Sequence:

ATGGAGCCAG GCGGGGCCCG TCTGCGTCTG CAGAGGACAG AAGGGCTGGG AGGGGAGCGG 
GAGCGCCAAC CCTGTGGAGA TGGAAACACT GAGACGCACA GAGCCCCGGA CTTGGTACAA 
TGGACCCGAC ACATGGAGGC TGTGAAGGCA CAATTGCTGG AGCAAGCGCA GGGACAACTG 
AGGGAGCTGC TGGATCGGGC CATGCGGGAG GCTATACAAT CCTACCCATC ACAAGACAAA 
CCTCTGCCCC CACCTCCCCC AGGTTCCTTG AGCAGTGAGC TGATGGAGGT GCAGCATTTC 
CGCACCATCT ACCACATGTT CATCGCTGGC CTGTGTGTCT TCATCATCAG CACCCTGGCC 
ATCGACTTCA TTGATGAGGG CAGGCTGCTG CTGGAGTTTG ACCTACTGAT CTTCAGCTTC 
GGACAGCTGC CATTGGCGCT GGTGACCTGG GTGCCCATGT TTCTGTCCAC CCTGTTGGCG 
CCGTACCAGG CCCTACGGCT GTGGGCCAGG GGCACCTGGA CGCAGGCGAC GGGCCTGGGC 
TGTGCGCTGC TAGCCGCCCA CGCCGTGGTG CTCTGCGCGC TGCCGGTCCA CGTGGCCGTG 
GAGCATCAGC TCCCGCCGGC CTCCCGTTGT GTCCTGGTCT TCGAGCAGGT TAGGTTCCTG 
ATGAAAAGCT ACTCCTTCCT GAGAGAGGCT GTGCCTGGGA CCCTTCGTGC CAGACGAGGT 
GAGGGGATCC AGGCCCCCAG TTTCTCCAGC TACCTCTACT TCCTCTTCTG CCCAACACTC 
ATCTACAGGG AGACTTACCC TAGGACGCCC TATGTCAGGT GGAATTATGT GGCCAAGAAC 
TTTGCCCAGG CCCTGGGATG TGTGCTCTAT GCCTGCTTCA TCCTGGGCCG CCTCTGTGTT 
CCTGTCTTTG CCAACATGAG CCGAGAGCCC TTCAGCACCC GTGCCCTGGT GCTCTCTATC 
CTGCATGCCA CGTTGCCAGG CATCTTCATG CTGCTGCTCA TCTTCTTTGC CTTCCTCCAT 
TGCTGGCTCA ACGCCTTTGC CGAGATGCTA CGATTTGGAG ACAGGATGTT CTACCGGGAC 
TGGTGGAACT CAACGTCCTT CTCCAACTAC TACCGCACTT GGAACGTGGT GGTCCATGAC 
TGGCTGTACA GCTACGTGTA TCAGGATGGG CTGCGGCTCC TTGGTGCCCG GGCCCGAGGG 
GTAGCCATGC TGGGTGTGTT CCTGGTCTCC GCAGTGGCCC ATGAGTATAT CTTCTGCTTC 
GTCCTGGGGT TCTTCTATCC CGTCATGCTG ATACTCTTCC TTGTCATTGG AGGAATGTTG 
AACTTCATGA TGCATGACCA GCGCACCGGC CCGGCATGGA ACGTGCTGAT GTGGACCATG 
CTGTTTCTAG GCCAGGGAAT CCAGGTCAGC CTGTACTGCC AGGAGTGGTA CGCACGGCGG 
CACTGCCCCT TACCCCAGGC AACTTTCTGG GGGCTGGTGA CACCTCGATC TTGGTCCTGC 
CATACCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SOAT2 ( XM_011538850.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011537152.1 Homo sapiens sterol O-acyltransferase 2 (SOAT2), transcript variant X3, mRNA.

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CloneID	OHu61768
Clone ID Related Accession (Same CDS sequence)	XM_011538850.2
Accession Version	XM_011538850.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1401bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	sterol O-acyltransferase 2 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000012.12) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011538850.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAGCCAG GCGGGGCCCG TCTGCGTCTG CAGAGGACAG AAGGGCTGGG AGGGGAGCGG 
GAGCGCCAAC CCTGTGGAGA TGGAAACACT GAGACGCACA GAGCCCCGGA CTTGGTACAA 
TGGACCCGAC ACATGGAGGC TGTGAAGGCA CAATTGCTGG AGCAAGCGCA GGGACAACTG 
AGGGAGCTGC TGGATCGGGC CATGCGGGAG GCTATACAAT CCTACCCATC ACAAGACAAA 
CCTCTGCCCC CACCTCCCCC AGGTTCCTTG AGCAGGCTGC TGCTGGAGTT TGACCTACTG 
ATCTTCAGCT TCGGACAGCT GCCATTGGCG CTGGTGACCT GGGTGCCCAT GTTTCTGTCC 
ACCCTGTTGG CGCCGTACCA GGCCCTACGG CTGTGGGCCA GGGGCACCTG GACGCAGGCG 
ACGGGCCTGG GCTGTGCGCT GCTAGCCGCC CACGCCGTGG TGCTCTGCGC GCTGCCGGTC 
CACGTGGCCG TGGAGCATCA GCTCCCGCCG GCCTCCCGTT GTGTCCTGGT CTTCGAGCAG 
GTTAGGTTCC TGATGAAAAG CTACTCCTTC CTGAGAGAGG CTGTGCCTGG GACCCTTCGT 
GCCAGACGAG GTGAGGGGAT CCAGGCCCCC AGTTTCTCCA GCTACCTCTA CTTCCTCTTC 
TGCCCAACAC TCATCTACAG GGAGACTTAC CCTAGGACGC CCTATGTCAG GTGGAATTAT 
GTGGCCAAGA ACTTTGCCCA GGCCCTGGGA TGTGTGCTCT ATGCCTGCTT CATCCTGGGC 
CGCCTCTGTG TTCCTGTCTT TGCCAACATG AGCCGAGAGC CCTTCAGCAC CCGTGCCCTG 
GTGCTCTCTA TCCTGCATGC CACGTTGCCA GGCATCTTCA TGCTGCTGCT CATCTTCTTT 
GCCTTCCTCC ATTGCTGGCT CAACGCCTTT GCCGAGATGC TACGATTTGG AGACAGGATG 
TTCTACCGGG ACTGGTGGAA CTCAACGTCC TTCTCCAACT ACTACCGCAC TTGGAACGTG 
GTGGTCCATG ACTGGCTGTA CAGCTACGTG TATCAGGATG GGCTGCGGCT CCTTGGTGCC 
CGGGCCCGAG GGGTAGCCAT GCTGGGTGTG TTCCTGGTCT CCGCAGTGGC CCATGAGTAT 
ATCTTCTGCT TCGTCCTGGG GTTCTTCTAT CCCGTCATGC TGATACTCTT CCTTGTCATT 
GGAGGAATGT TGAACTTCAT GATGCATGAC CAGCGCACCG GCCCGGCATG GAACGTGCTG 
ATGTGGACCA TGCTGTTTCT AGGCCAGGGA ATCCAGGTCA GCCTGTACTG CCAGGAGTGG 
TACGCACGGC GGCACTGCCC CTTACCCCAG GCAACTTTCT GGGGGCTGGT GACACCTCGA 
TCTTGGTCCT GCCATACCTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011537152.1
CDS	1142..2542
Translation	MEPGGARLRLQRTEGLGGERERQPCGDGNTETHRAPDLVQWTRHMEAVKAQLLEQAQGQLRELLDRAMREAIQSYPSQDKPLPPPPPGSLSRLLLEFDLLIFSFGQLPLALVTWVPMFLSTLLAPYQALRLWARGTWTQATGLGCALLAAHAVVLCALPVHVAVEHQLPPASRCVLVFEQVRFLMKSYSFLREAVPGTLRARRGEGIQAPSFSSYLYFLFCPTLIYRETYPRTPYVRWNYVAKNFAQALGCVLYACFILGRLCVPVFANMSREPFSTRALVLSILHATLPGIFMLLLIFFAFLHCWLNAFAEMLRFGDRMFYRDWWNSTSFSNYYRTWNVVVHDWLYSYVYQDGLRLLGARARGVAMLGVFLVSAVAHEYIFCFVLGFFYPVMLILFLVIGGMLNFMMHDQRTGPAWNVLMWTMLFLGQGIQVSLYCQEWYARRHCPLPQATFWGLVTPRSWSCHT

Target ORF information:

RefSeq Version	XM_011538850.2
Organism	Homo sapiens(human)
Definition	Homo sapiens sterol O-acyltransferase 2 (SOAT2), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011538850.2

ORF Insert Sequence:

ATGGAGCCAG GCGGGGCCCG TCTGCGTCTG CAGAGGACAG AAGGGCTGGG AGGGGAGCGG 
GAGCGCCAAC CCTGTGGAGA TGGAAACACT GAGACGCACA GAGCCCCGGA CTTGGTACAA 
TGGACCCGAC ACATGGAGGC TGTGAAGGCA CAATTGCTGG AGCAAGCGCA GGGACAACTG 
AGGGAGCTGC TGGATCGGGC CATGCGGGAG GCTATACAAT CCTACCCATC ACAAGACAAA 
CCTCTGCCCC CACCTCCCCC AGGTTCCTTG AGCAGGCTGC TGCTGGAGTT TGACCTACTG 
ATCTTCAGCT TCGGACAGCT GCCATTGGCG CTGGTGACCT GGGTGCCCAT GTTTCTGTCC 
ACCCTGTTGG CGCCGTACCA GGCCCTACGG CTGTGGGCCA GGGGCACCTG GACGCAGGCG 
ACGGGCCTGG GCTGTGCGCT GCTAGCCGCC CACGCCGTGG TGCTCTGCGC GCTGCCGGTC 
CACGTGGCCG TGGAGCATCA GCTCCCGCCG GCCTCCCGTT GTGTCCTGGT CTTCGAGCAG 
GTTAGGTTCC TGATGAAAAG CTACTCCTTC CTGAGAGAGG CTGTGCCTGG GACCCTTCGT 
GCCAGACGAG GTGAGGGGAT CCAGGCCCCC AGTTTCTCCA GCTACCTCTA CTTCCTCTTC 
TGCCCAACAC TCATCTACAG GGAGACTTAC CCTAGGACGC CCTATGTCAG GTGGAATTAT 
GTGGCCAAGA ACTTTGCCCA GGCCCTGGGA TGTGTGCTCT ATGCCTGCTT CATCCTGGGC 
CGCCTCTGTG TTCCTGTCTT TGCCAACATG AGCCGAGAGC CCTTCAGCAC CCGTGCCCTG 
GTGCTCTCTA TCCTGCATGC CACGTTGCCA GGCATCTTCA TGCTGCTGCT CATCTTCTTT 
GCCTTCCTCC ATTGCTGGCT CAACGCCTTT GCCGAGATGC TACGATTTGG AGACAGGATG 
TTCTACCGGG ACTGGTGGAA CTCAACGTCC TTCTCCAACT ACTACCGCAC TTGGAACGTG 
GTGGTCCATG ACTGGCTGTA CAGCTACGTG TATCAGGATG GGCTGCGGCT CCTTGGTGCC 
CGGGCCCGAG GGGTAGCCAT GCTGGGTGTG TTCCTGGTCT CCGCAGTGGC CCATGAGTAT 
ATCTTCTGCT TCGTCCTGGG GTTCTTCTAT CCCGTCATGC TGATACTCTT CCTTGTCATT 
GGAGGAATGT TGAACTTCAT GATGCATGAC CAGCGCACCG GCCCGGCATG GAACGTGCTG 
ATGTGGACCA TGCTGTTTCT AGGCCAGGGA ATCCAGGTCA GCCTGTACTG CCAGGAGTGG 
TACGCACGGC GGCACTGCCC CTTACCCCAG GCAACTTTCT GGGGGCTGGT GACACCTCGA 
TCTTGGTCCT GCCATACCTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SOAT2 ( XM_011538851.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011537153.1 Homo sapiens sterol O-acyltransferase 2 (SOAT2), transcript variant X5, mRNA.

Price & Availability↑

CloneID	OHu61769
Clone ID Related Accession (Same CDS sequence)	XM_011538851.2
Accession Version	XM_011538851.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 837bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	sterol O-acyltransferase 2 isoform X3
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000012.12) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011538851.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAGCCAG GCGGGGCCCG TCTGCGTCTG CAGAGGACAG AAGGGCTGGG AGGGGAGCGG 
GAGCGCCAAC CCTGTGGAGA TGGAAACACT GAGACGCACA GAGCCCCGGA CTTGGTACAA 
TGGACCCGAC ACATGGAGGC TGTGAAGGCA CAATTGCTGG AGCAAGCGCA GGGACAACTG 
AGGGAGCTGC TGGATCGGGC CATGCGGGAG GCTATACAAT CCTACCCATC ACAAGACAAA 
CCTCTGCCCC CACCTCCCCC AGGTTCCTTG AGCAGGACCC AGGAGCCATC CCTGGGGAAA 
CAGAAAGTTT TCATCATCCG CAAGTCCCTG CTTGATGAGC TGATGGAGGT GCAGCATTTC 
CGCACCATCT ACCACATGTT CATCGCTGGC CTGTGTGTCT TCATCATCAG CACCCTGGCC 
ATCGACTTCA TTGATGAGGG CAGGCTGCTG CTGGAGTTTG ACCTACTGAT CTTCAGCTTC 
GGACAGCTGC CATTGGCGCT GGTGACCTGG GTGCCCATGT TTCTGTCCAC CCTGTTGGCG 
CCGTACCAGG CCCTACGGCT GTGGGCCAGG GGCACCTGGA CGCAGGCGAC GGGCCTGGGC 
TGTGCGCTGC TAGCCGCCCA CGCCGTGGTG CTCTGCGCGC TGCCGGTCCA CGTGGCCGTG 
GAGCATCAGC TCCCGCCGGC CTCCCGTTGT GTCCTGGTCT TCGAGCAGGT TAGGTTCCTG 
ATGAAAAGCT ACTCCTTCCT GAGAGAGGCT GTGCCTGGGA CCCTTCGTGC CAGACGAGCG 
AATAGGAAAG CTCGAGGAGA ACAGAAGAGA TGGGAGAATG GCCGGTCAGC AGAGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011537153.1
CDS	1142..1978
Translation	MEPGGARLRLQRTEGLGGERERQPCGDGNTETHRAPDLVQWTRHMEAVKAQLLEQAQGQLRELLDRAMREAIQSYPSQDKPLPPPPPGSLSRTQEPSLGKQKVFIIRKSLLDELMEVQHFRTIYHMFIAGLCVFIISTLAIDFIDEGRLLLEFDLLIFSFGQLPLALVTWVPMFLSTLLAPYQALRLWARGTWTQATGLGCALLAAHAVVLCALPVHVAVEHQLPPASRCVLVFEQVRFLMKSYSFLREAVPGTLRARRANRKARGEQKRWENGRSAE

Target ORF information:

RefSeq Version	XM_011538851.2
Organism	Homo sapiens(human)
Definition	Homo sapiens sterol O-acyltransferase 2 (SOAT2), transcript variant X5, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011538851.2

ORF Insert Sequence:

ATGGAGCCAG GCGGGGCCCG TCTGCGTCTG CAGAGGACAG AAGGGCTGGG AGGGGAGCGG 
GAGCGCCAAC CCTGTGGAGA TGGAAACACT GAGACGCACA GAGCCCCGGA CTTGGTACAA 
TGGACCCGAC ACATGGAGGC TGTGAAGGCA CAATTGCTGG AGCAAGCGCA GGGACAACTG 
AGGGAGCTGC TGGATCGGGC CATGCGGGAG GCTATACAAT CCTACCCATC ACAAGACAAA 
CCTCTGCCCC CACCTCCCCC AGGTTCCTTG AGCAGGACCC AGGAGCCATC CCTGGGGAAA 
CAGAAAGTTT TCATCATCCG CAAGTCCCTG CTTGATGAGC TGATGGAGGT GCAGCATTTC 
CGCACCATCT ACCACATGTT CATCGCTGGC CTGTGTGTCT TCATCATCAG CACCCTGGCC 
ATCGACTTCA TTGATGAGGG CAGGCTGCTG CTGGAGTTTG ACCTACTGAT CTTCAGCTTC 
GGACAGCTGC CATTGGCGCT GGTGACCTGG GTGCCCATGT TTCTGTCCAC CCTGTTGGCG 
CCGTACCAGG CCCTACGGCT GTGGGCCAGG GGCACCTGGA CGCAGGCGAC GGGCCTGGGC 
TGTGCGCTGC TAGCCGCCCA CGCCGTGGTG CTCTGCGCGC TGCCGGTCCA CGTGGCCGTG 
GAGCATCAGC TCCCGCCGGC CTCCCGTTGT GTCCTGGTCT TCGAGCAGGT TAGGTTCCTG 
ATGAAAAGCT ACTCCTTCCT GAGAGAGGCT GTGCCTGGGA CCCTTCGTGC CAGACGAGCG 
AATAGGAAAG CTCGAGGAGA ACAGAAGAGA TGGGAGAATG GCCGGTCAGC AGAGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Cholesterol and fatty acids regulate cysteine ubiquitylation of ACAT2 through competitive oxidation.
Nature cell biology19(7)808-819(2017 Jul)
Wang YJ,Bian Y,Luo J,Lu M,Xiong Y,Guo SY,Yin HY,Lin X,Li Q,Chang CCY,Chang TY,Li BL,Song BL

The ACAT2 expression of human leukocytes is responsible for the excretion of lipoproteins containing cholesteryl/steryl esters.
Acta biochimica et biophysica Sinica48(11)990-997(2016 Nov)
Guo D,Zhang X,Li Q,Qian L,Xu J,Lu M,Hu X,Zhu M,Chang CC,Song B,Chang T,Xiong Y,Li B

Prognostic significance of two lipid metabolism enzymes, HADHA and ACAT2, in clear cell renal cell carcinoma.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine37(6)8121-30(2016 Jun)
Zhao Z,Lu J,Han L,Wang X,Man Q,Liu S

Functional characterization of two single nucleotide polymorphisms of acyl-coenzyme A:cholesterol acyltransferase 2.
Gene566(2)236-41(2015 Jul)
He X,Leow KY,Yang H,Heng CK

TG-interacting factor 1 acts as a transcriptional repressor of sterol O-acyltransferase 2.
Journal of lipid research55(4)709-17(2014 Apr)
Pramfalk C,Melhuish TA,Wotton D,Jiang ZY,Eriksson M,Parini P

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SOAT2 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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