ACBD6 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	ACBD6
Entrez Gene ID	84320
Full Name	acyl-CoA binding domain containing 6
General protein information	Preferred Names acyl-CoA binding domain containing 6 Names acyl-CoA-binding domain-containing protein 6 acyl-Coenzyme A binding domain containing 6
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 1 Map Location: 1q25.2-q25.3
Disorder MIM:	616352

mRNA and Protein(s)

mRNA	Protein	Name
NM_032360.3	NP_115736.1	acyl-CoA-binding domain-containing protein 6
NM_032360.4	NP_115736.1	acyl-CoA-binding domain-containing protein 6

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	ACBD6	XP_524985.1
	ACBD6	XP_001115044.1
Gallus gallus (chicken)	ACBD6	NP_001264476.1
Arabidopsis thaliana (thale cress)	ACBP1	NP_200159.1
Mus musculus (house mouse)	Acbd6	NP_082526.2
Xenopus tropicalis (tropical clawed frog)	acbd6	NP_001008065.2
Bos taurus (cattle)	ACBD6	NP_001077252.1
Danio rerio (zebrafish)	acbd6	NP_001020626.1
Drosophila melanogaster (fruit fly)	CG33713	NP_001027085.1
Caenorhabditis elegans (roundworm)	acbp-5	NP_499817.2
Arabidopsis thaliana (thale cress)	ACBP2	NP_194507.1
Rattus norvegicus (Norway rat)	Acbd6	NP_001011906.1
Homo sapiens (human)	ACBD6	NP_115736.1
Canis lupus familiaris (dog)	ACBD6	XP_537152.2
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP000752	XP_311287.5
Oryza sativa (rice)	Os04g0681900	NP_001054292.1

Gene Ontology
Bibliography

Related articles in PubMed

Association of NMT2 with the acyl-CoA carrier ACBD6 protects the N-myristoyltransferase reaction from palmitoyl-CoA.
Soupene E, Kao J, Cheng DH, Wang D, Greninger AL, Knudsen GM, DeRisi JL, Kuypers FA
Journal of lipid research57(2)288-98(2016 Feb)

Ligand binding to the ACBD6 protein regulates the acyl-CoA transferase reactions in membranes.
Soupene E, Kuypers FA
Journal of lipid research56(10)1961-71(2015 Oct)

Characterization of an acyl-coenzyme A binding protein predominantly expressed in human primitive progenitor cells.
Soupene E, Serikov V, Kuypers FA
Journal of lipid research49(5)1103-12(2008 May)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

ligand binding properties of the NMT/ACBD6 complex can explain how the NMT reaction can proceed in the presence of the very abundant competitive substrate, C(16)-CoA.
Title: Association of NMT2 with the acyl-CoA carrier ACBD6 protects the N-myristoyltransferase reaction from palmitoyl-CoA.

Findings provide evidence that the binding properties of ACBD6 are adapted to prevent its constant saturation by the very abundant C16:0-CoA and protect membrane systems.
Title: Ligand binding to the ACBD6 protein regulates the acyl-CoA transferase reactions in membranes.

Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)
Title: Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.

ACBD6 is a modular protein that carries an acyl-CoA binding domain at its N terminus and two ankyrin motifs at its C terminus.
Title: Characterization of an acyl-coenzyme A binding protein predominantly expressed in human primitive progenitor cells.

The following ACBD6 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the ACBD6 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu04984	NM_032360.4 Latest version!	Homo sapiens acyl-CoA binding domain containing 6 (ACBD6), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
View Old Accession Versions >>
OHu04984	NM_032360.3	Homo sapiens acyl-CoA binding domain containing 6 (ACBD6), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
Hide Old Accession Versions >>

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

ACBD6 ( NM_032360.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_115736.1 Homo sapiens acyl-CoA binding domain containing 6 (ACBD6), mRNA.

Price & Availability↑

CloneID	OHu04984
Clone ID Related Accession (Same CDS sequence)	NM_032360.3 , NM_032360.4
Accession Version	NM_032360.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 849bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-01
Organism	Homo sapiens(human)
Product	acyl-CoA-binding domain-containing protein 6
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL537685.3, AL561590.3, BU170874.1, AK314112.1 and AA085012.1. On Apr 8, 2009 this sequence version replaced NM_032360.2. ##Evidence-Data-START## Transcript exon combination :: SRR1163658.364113.1, SRR1163655.287540.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2159607, SAMEA2162568 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCTTCAT CATTCCTGCC CGCGGGGGCC ATCACCGGCG ACAGCGGTGG AGAGCTGAGC 
TCAGGGGACG ACTCCGGGGA GGTGGAGTTC CCCCATAGCC CTGAGATCGA GGAGACCAGT 
TGCCTGGCCG AGCTGTTTGA GAAGGCTGCC GCGCACCTGC AAGGCCTGAT TCAGGTGGCC 
AGCAGGGAGC AGCTCTTGTA CCTGTATGCC AGGTACAAAC AGGTCAAAGT TGGAAATTGT 
AATACTCCTA AACCAAGCTT CTTTGATTTT GAAGGAAAGC AAAAATGGGA AGCTTGGAAA 
GCACTTGGTG ATTCAAGCCC CAGCCAAGCA ATGCAGGAAT ATATCGCAGT AGTTAAAAAA 
CTAGATCCAG GTTGGAATCC TCAGATACCA GAGAAGAAAG GAAAAGAAGC AAATACAGGT 
TTTGGTGGGC CAGTTATTAG TTCTCTATAT CATGAAGAAA CCATCAGGGA AGAAGACAAA 
AATATATTTG ATTACTGCAG GGAAAACAAC ATTGACCATA TAACCAAAGC CATCAAATCG 
AAAAATGTGG ATGTGAATGT GAAAGATGAA GAGGGTAGGG CTCTACTTCA CTGGGCCTGT 
GATCGAGGAC ATAAGGAACT AGTCACAGTG TTGCTGCAAC ATAGAGCTGA CATTAACTGT 
CAGGACAATG AAGGCCAAAC AGCTCTACAT TATGCCTCTG CCTGTGAGTT TCTGGATATT 
GTAGAGCTGC TGCTCCAGTC TGGTGCTGAC CCCACTCTCC GAGACCAGGA TGGCTGCCTG 
CCAGAGGAGG TGACAGGCTG CAAAACAGTT TCTTTGGTGC TGCAGCGGCA CACAACTGGC 
AAGGCTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_115736.1
CDS	622..1470
Translation	MASSFLPAGAITGDSGGELSSGDDSGEVEFPHSPEIEETSCLAELFEKAAAHLQGLIQVASREQLLYLYARYKQVKVGNCNTPKPSFFDFEGKQKWEAWKALGDSSPSQAMQEYIAVVKKLDPGWNPQIPEKKGKEANTGFGGPVISSLYHEETIREEDKNIFDYCRENNIDHITKAIKSKNVDVNVKDEEGRALLHWACDRGHKELVTVLLQHRADINCQDNEGQTALHYASACEFLDIVELLLQSGADPTLRDQDGCLPEEVTGCKTVSLVLQRHTTGKA

Target ORF information:

RefSeq Version	NM_032360.3
Organism	Homo sapiens(human)
Definition	Homo sapiens acyl-CoA binding domain containing 6 (ACBD6), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_032360.3

ORF Insert Sequence:

ATGGCTTCAT CATTCCTGCC CGCGGGGGCC ATCACCGGCG ACAGCGGTGG AGAGCTGAGC 
TCAGGGGACG ACTCCGGGGA GGTGGAGTTC CCCCATAGCC CTGAGATCGA GGAGACCAGT 
TGCCTGGCCG AGCTGTTTGA GAAGGCTGCC GCGCACCTGC AAGGCCTGAT TCAGGTGGCC 
AGCAGGGAGC AGCTCTTGTA CCTGTATGCC AGGTACAAAC AGGTCAAAGT TGGAAATTGT 
AATACTCCTA AACCAAGCTT CTTTGATTTT GAAGGAAAGC AAAAATGGGA AGCTTGGAAA 
GCACTTGGTG ATTCAAGCCC CAGCCAAGCA ATGCAGGAAT ATATCGCAGT AGTTAAAAAA 
CTAGATCCAG GTTGGAATCC TCAGATACCA GAGAAGAAAG GAAAAGAAGC AAATACAGGT 
TTTGGTGGGC CAGTTATTAG TTCTCTATAT CATGAAGAAA CCATCAGGGA AGAAGACAAA 
AATATATTTG ATTACTGCAG GGAAAACAAC ATTGACCATA TAACCAAAGC CATCAAATCG 
AAAAATGTGG ATGTGAATGT GAAAGATGAA GAGGGTAGGG CTCTACTTCA CTGGGCCTGT 
GATCGAGGAC ATAAGGAACT AGTCACAGTG TTGCTGCAAC ATAGAGCTGA CATTAACTGT 
CAGGACAATG AAGGCCAAAC AGCTCTACAT TATGCCTCTG CCTGTGAGTT TCTGGATATT 
GTAGAGCTGC TGCTCCAGTC TGGTGCTGAC CCCACTCTCC GAGACCAGGA TGGCTGCCTG 
CCAGAGGAGG TGACAGGCTG CAAAACAGTT TCTTTGGTGC TGCAGCGGCA CACAACTGGC 
AAGGCTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ACBD6 ( NM_032360.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_115736.1 Homo sapiens acyl-CoA binding domain containing 6 (ACBD6), mRNA.

Price & Availability↑

CloneID	OHu04984
Clone ID Related Accession (Same CDS sequence)	NM_032360.3 , NM_032360.4
Accession Version	NM_032360.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 849bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2020-01-01
Organism	Homo sapiens(human)
Product	acyl-CoA-binding domain-containing protein 6
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BU170874.1, AK314112.1 and AA085012.1. On Nov 23, 2018 this sequence version replaced NM_032360.3. ##Evidence-Data-START## Transcript exon combination :: SRR3476690.359293.1, SRR3476690.996350.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2159607, SAMEA2162568 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000367595.4/ ENSP00000356567.3 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGCTTCAT CATTCCTGCC CGCGGGGGCC ATCACCGGCG ACAGCGGTGG AGAGCTGAGC 
TCAGGGGACG ACTCCGGGGA GGTGGAGTTC CCCCATAGCC CTGAGATCGA GGAGACCAGT 
TGCCTGGCCG AGCTGTTTGA GAAGGCTGCC GCGCACCTGC AAGGCCTGAT TCAGGTGGCC 
AGCAGGGAGC AGCTCTTGTA CCTGTATGCC AGGTACAAAC AGGTCAAAGT TGGAAATTGT 
AATACTCCTA AACCAAGCTT CTTTGATTTT GAAGGAAAGC AAAAATGGGA AGCTTGGAAA 
GCACTTGGTG ATTCAAGCCC CAGCCAAGCA ATGCAGGAAT ATATCGCAGT AGTTAAAAAA 
CTAGATCCAG GTTGGAATCC TCAGATACCA GAGAAGAAAG GAAAAGAAGC AAATACAGGT 
TTTGGTGGGC CAGTTATTAG TTCTCTATAT CATGAAGAAA CCATCAGGGA AGAAGACAAA 
AATATATTTG ATTACTGCAG GGAAAACAAC ATTGACCATA TAACCAAAGC CATCAAATCG 
AAAAATGTGG ATGTGAATGT GAAAGATGAA GAGGGTAGGG CTCTACTTCA CTGGGCCTGT 
GATCGAGGAC ATAAGGAACT AGTCACAGTG TTGCTGCAAC ATAGAGCTGA CATTAACTGT 
CAGGACAATG AAGGCCAAAC AGCTCTACAT TATGCCTCTG CCTGTGAGTT TCTGGATATT 
GTAGAGCTGC TGCTCCAGTC TGGTGCTGAC CCCACTCTCC GAGACCAGGA TGGCTGCCTG 
CCAGAGGAGG TGACAGGCTG CAAAACAGTT TCTTTGGTGC TGCAGCGGCA CACAACTGGC 
AAGGCTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_115736.1
CDS	312..1160
Translation	MASSFLPAGAITGDSGGELSSGDDSGEVEFPHSPEIEETSCLAELFEKAAAHLQGLIQVASREQLLYLYARYKQVKVGNCNTPKPSFFDFEGKQKWEAWKALGDSSPSQAMQEYIAVVKKLDPGWNPQIPEKKGKEANTGFGGPVISSLYHEETIREEDKNIFDYCRENNIDHITKAIKSKNVDVNVKDEEGRALLHWACDRGHKELVTVLLQHRADINCQDNEGQTALHYASACEFLDIVELLLQSGADPTLRDQDGCLPEEVTGCKTVSLVLQRHTTGKA

Target ORF information:

RefSeq Version	NM_032360.4
Organism	Homo sapiens(human)
Definition	Homo sapiens acyl-CoA binding domain containing 6 (ACBD6), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_032360.4

ORF Insert Sequence:

ATGGCTTCAT CATTCCTGCC CGCGGGGGCC ATCACCGGCG ACAGCGGTGG AGAGCTGAGC 
TCAGGGGACG ACTCCGGGGA GGTGGAGTTC CCCCATAGCC CTGAGATCGA GGAGACCAGT 
TGCCTGGCCG AGCTGTTTGA GAAGGCTGCC GCGCACCTGC AAGGCCTGAT TCAGGTGGCC 
AGCAGGGAGC AGCTCTTGTA CCTGTATGCC AGGTACAAAC AGGTCAAAGT TGGAAATTGT 
AATACTCCTA AACCAAGCTT CTTTGATTTT GAAGGAAAGC AAAAATGGGA AGCTTGGAAA 
GCACTTGGTG ATTCAAGCCC CAGCCAAGCA ATGCAGGAAT ATATCGCAGT AGTTAAAAAA 
CTAGATCCAG GTTGGAATCC TCAGATACCA GAGAAGAAAG GAAAAGAAGC AAATACAGGT 
TTTGGTGGGC CAGTTATTAG TTCTCTATAT CATGAAGAAA CCATCAGGGA AGAAGACAAA 
AATATATTTG ATTACTGCAG GGAAAACAAC ATTGACCATA TAACCAAAGC CATCAAATCG 
AAAAATGTGG ATGTGAATGT GAAAGATGAA GAGGGTAGGG CTCTACTTCA CTGGGCCTGT 
GATCGAGGAC ATAAGGAACT AGTCACAGTG TTGCTGCAAC ATAGAGCTGA CATTAACTGT 
CAGGACAATG AAGGCCAAAC AGCTCTACAT TATGCCTCTG CCTGTGAGTT TCTGGATATT 
GTAGAGCTGC TGCTCCAGTC TGGTGCTGAC CCCACTCTCC GAGACCAGGA TGGCTGCCTG 
CCAGAGGAGG TGACAGGCTG CAAAACAGTT TCTTTGGTGC TGCAGCGGCA CACAACTGGC 
AAGGCTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Association of NMT2 with the acyl-CoA carrier ACBD6 protects the N-myristoyltransferase reaction from palmitoyl-CoA.
Journal of lipid research57(2)288-98(2016 Feb)
Soupene E,Kao J,Cheng DH,Wang D,Greninger AL,Knudsen GM,DeRisi JL,Kuypers FA

Ligand binding to the ACBD6 protein regulates the acyl-CoA transferase reactions in membranes.
Journal of lipid research56(10)1961-71(2015 Oct)
Soupene E,Kuypers FA

Characterization of an acyl-coenzyme A binding protein predominantly expressed in human primitive progenitor cells.
Journal of lipid research49(5)1103-12(2008 May)
Soupene E,Serikov V,Kuypers FA