MEX3B cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	MEX3B
Entrez Gene ID	84206
Full Name	mex-3 RNA binding family member B
Synonyms	MEX-3B,RKHD3,RNF195
General protein information	Preferred Names mex-3 RNA binding family member B Names RNA-binding protein MEX3B RING finger protein 195 ring finger and KH domain containing 3
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 15 Map Location: 15q25.2
Summary	This gene encodes an RNA-binding phosphoprotein that is part of the MEX3 (muscle excess 3) family of translational regulators. The encoded protein contains N-terminal nuclear export and nuclear localization signals and is exported from the cytoplasm to the nucleus. The protein binds to RNA via two KH domains and also colocalizes with MEX3A, Dcp1A decapping factor and Argonaute proteins within P (processing) bodies. [provided by RefSeq, Oct 2012].
Disorder MIM:	611008

mRNA and Protein(s)

mRNA	Protein	Name
NM_032246.5	NP_115622.2	RNA-binding protein MEX3B
NM_032246.6	NP_115622.2	RNA-binding protein MEX3B
NM_032246.4	NP_115622.2	RNA-binding protein MEX3B

Pathways from BioSystems

Homologies

Homo sapiens (human)	MEX3B	NP_115622.2
Canis lupus familiaris (dog)	MEX3B	XP_005618463.1
Rattus norvegicus (Norway rat)	Mex3b	NP_001178555.1
	MEX3B	XP_001110186.1
Xenopus tropicalis (tropical clawed frog)	mex3b	XP_002932296.1
Pan troglodytes (chimpanzee)	MEX3B	XP_523137.2
Danio rerio (zebrafish)	mex3b	NP_001074462.1
Bos taurus (cattle)	MEX3B	XP_005221946.1
Mus musculus (house mouse)	Mex3b	NP_780575.2

Gene Ontology
Bibliography

Related articles in PubMed

A genome-wide association study of clinical symptoms of dissociation in a trauma-exposed sample.
Wolf EJ, Rasmusson AM, Mitchell KS, Logue MW, Baldwin CT, Miller MW
Depression and anxiety31(4)352-60(2014 Apr)

The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.
Baltz AG, Munschauer M, Schwanh?usser B, Vasile A, Murakawa Y, Schueler M, Youngs N, Penfold-Brown D, Drew K, Milek M, Wyler E, Bonneau R, Selbach M, Dieterich C, Landthaler M
Molecular cell46(5)674-90(2012 Jun)

Six new loci associated with body mass index highlight a neuronal influence on body weight regulation.
Willer CJ, Speliotes EK, Loos RJ, Li S, Lindgren CM, Heid IM, Berndt SI, Elliott AL, Jackson AU, Lamina C, Lettre G, Lim N, Lyon HN, McCarroll SA, Papadakis K, Qi L, Randall JC, Roccasecca RM, Sanna S, Scheet P, Weedon MN, Wheeler E, Zhao JH, Jacobs LC, Prokopenko I, Soranzo N, Tanaka T, Timpson NJ, Almgren P, Bennett A, Bergman RN, Bingham SA, Bonnycastle LL, Brown M, Burtt NP, Chines P, Coin L, Collins FS, Connell JM, Cooper C, Smith GD, Dennison EM, Deodhar P, Elliott P, Erdos MR, Estrada K, Evans DM, Gianniny L, Gieger C, Gillson CJ, Guiducci C, Hackett R, Hadley D, Hall AS, Havulinna AS, Hebebrand J, Hofman A, Isomaa B, Jacobs KB, Johnson T, Jousilahti P, Jovanovic Z, Khaw KT, Kraft P, Kuokkanen M, Kuusisto J, Laitinen J, Lakatta EG, Luan J, Luben RN, Mangino M, McArdle WL, Meitinger T, Mulas A, Munroe PB, Narisu N, Ness AR, Northstone K, O'Rahilly S, Purmann C, Rees MG, Ridderstr?le M, Ring SM, Rivadeneira F, Ruokonen A, Sandhu MS, Saramies J, Scott LJ, Scuteri A, Silander K, Sims MA, Song K, Stephens J, Stevens S, Stringham HM, Tung YC, Valle TT, Van Duijn CM, Vimaleswaran KS, Vollenweider P, Waeber G, Wallace C, Watanabe RM, Waterworth DM, Watkins N, , Witteman JC, Zeggini E, Zhai G, Zillikens MC, Altshuler D, Caulfield MJ, Chanock SJ, Farooqi IS, Ferrucci L, Guralnik JM, Hattersley AT, Hu FB, Jarvelin MR, Laakso M, Mooser V, Ong KK, Ouwehand WH, Salomaa V, Samani NJ, Spector TD, Tuomi T, Tuomilehto J, Uda M, Uitterlinden AG, Wareham NJ, Deloukas P, Frayling TM, Groop LC, Hayes RB, Hunter DJ, Mohlke KL, Peltonen L, Schlessinger D, Strachan DP, Wichmann HE, McCarthy MI, Boehnke M, Barroso I, Abecasis GR, Hirschhorn JN,
Nature genetics41(1)25-34(2009 Jan)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

14-3-3 exerts combined effects on hMex-3B and acts as a major regulator of the sorting between distinct classes of RNA granules
Title: Interaction with 14-3-3 adaptors regulates the sorting of hMex-3B RNA-binding protein to distinct classes of RNA granules.

The following MEX3B gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the MEX3B cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu00607	NM_032246.6 Latest version!	Homo sapiens mex-3 RNA binding family member B (MEX3B), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$219.50-$307.30 $439.00
View Old Accession Versions >>
OHu00607	NM_032246.5	Homo sapiens mex-3 RNA binding family member B (MEX3B), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$219.50-$307.30 $439.00
OHu00607	NM_032246.4	Homo sapiens mex-3 RNA binding family member B (MEX3B), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$219.50-$307.30 $439.00
Hide Old Accession Versions >>

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***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

MEX3B ( NM_032246.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_115622.2 Homo sapiens mex-3 RNA binding family member B (MEX3B), mRNA.

Price & Availability↑

CloneID	OHu00607
Clone ID Related Accession (Same CDS sequence)	NM_032246.5 , NM_032246.6 , NM_032246.4
Accession Version	NM_032246.5	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1710bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-05-01
Organism	Homo sapiens(human)
Product	RNA-binding protein MEX3B
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK131424.1, BC111545.1, AB095929.1 and AA442153.1. On Nov 23, 2018 this sequence version replaced NM_032246.4. ##Evidence-Data-START## Transcript exon combination :: AK131424.1, BC036211.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGCCCAGCT CGCTGTTCGC AGACCTGGAG CGCAACGGCA GCGGCGGCGG CGGCGGCGGC 
AGCAGCGGAG GGGGAGAGAC CCTGGATGAC CAAAGAGCCC TGCAGCTCGC GCTCGACCAG 
CTCTCCCTGC TGGGGCTGGA CAGTGACGAG GGCGCCTCTC TGTACGACAG CGAGCCGCGC 
AAGAAGAGCG TGAACATGAC CGAGTGCGTG CCAGTACCCA GTTCTGAGCA TGTCGCCGAG 
ATCGTGGGGC GGCAAGGTTG TAAAATCAAA GCGCTGCGGG CGAAGACCAA TACTTACATC 
AAGACCCCAG TTCGCGGGGA GGAGCCTGTC TTTGTTGTGA CGGGCAGGAA GGAGGATGTG 
GCCATGGCTC GGAGGGAGAT CATCTCTGCT GCCGAGCACT TCTCCATGAT CCGCGCCTCC 
CGGAATAAGA ACACGGCACT CAACGGCGCG GTGCCTGGGC CGCCCAACCT GCCCGGGCAG 
ACCACCATCC AAGTGCGGGT ACCCTACCGC GTGGTGGGGC TCGTGGTGGG GCCCAAAGGC 
GCCACAATCA AGCGCATCCA GCAGCAGACG CACACGTACA TCGTGACGCC CAGCCGGGAT 
AAGGAGCCGG TGTTCGAGGT GACCGGCATG CCAGAGAACG TGGATCGCGC TCGAGAGGAG 
ATTGAGGCGC ACATTGCTCT GCGTACCGGC GGCATCATTG AGCTCACAGA CGAGAACGAC 
TTCCACGCCA ACGGCACCGA TGTGGGCTTC GATCTGCATC ATGGGTCCGG CGGGTCCGGC 
CCAGGCAGCC TCTGGAGCAA GCCCACCCCC AGCATCACGC CCACCCCCGG CCGCAAGCCT 
TTCTCTAGCT ACCGCAACGA CAGCTCCAGC TCGCTTGGCA GTGCTTCCAC AGACTCTTAT 
TTCGGCGGCG GGACCAGCAG CAGCGCAGCG GCTACCCAGC GCCTGGCGGA CTACAGCCCC 
CCTAGCCCCG CCCTGAGCTT TGCGCACAAC GGAAACAATA ACAATAACGG CAATGGGTAC 
ACCTACACAG CGGGGGGAGA AGCCTCAGTG CCATCCCCCG ACGGCTGCCC CGAGCTGCAG 
CCCACTTTTG ACCCGGCTCC CGCTCCCCCA CCTGGGGCAC CACTTATCTG GGCCCAGTTC 
GAGCGGTCCC CGGGAGGCGG ACCTGCAGCT CCGGTATCTT CTTCCTGCTC TTCTTCTGCA 
TCTTCGTCTG CTTCTTCCTC CTCCGTGGTC TTCCCCGGGG GTGGCGCCAG TGCGCCCTCC 
AACGCCAACC TGGGGCTATT GGTGCACCGC CGGCTGCACC CTGGCACCAG CTGCCCGCGC 
CTGTCTCCAC CCTTGCACAT GGCCCCGGGG GCGGGAGAGC ACCACCTGGC TCGCCGGGTG 
CGCAGCGACC CGGGTGGAGG AGGCCTGGCC TACGCCGCTT ATGCCAACGG GCTGGGGGCA 
CAGCTGCCTG GCTTGCAGCC GTCGGACACG TCGGGCTCCT CCTCTTCGTC CAGCTCCTCC 
TCCAGCTCTT CATCCTCTTC CTCCGGGCTT CGGCGTAAAG GCAGCCGCGA CTGCTCCGTG 
TGCTTCGAGA GCGAAGTGAT TGCCGCGCTG GTGCCCTGTG GCCACAACCT CTTCTGCATG 
GAGTGCGCCA ATCGCATCTG TGAGAAGAGC GAGCCCGAGT GCCCGGTCTG CCACACCGCG 
GTCACTCAGG CCATCCGCAT CTTTTCTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_115622.2
CDS	314..2023
Translation	MPSSLFADLERNGSGGGGGGSSGGGETLDDQRALQLALDQLSLLGLDSDEGASLYDSEPRKKSVNMTECVPVPSSEHVAEIVGRQGCKIKALRAKTNTYIKTPVRGEEPVFVVTGRKEDVAMARREIISAAEHFSMIRASRNKNTALNGAVPGPPNLPGQTTIQVRVPYRVVGLVVGPKGATIKRIQQQTHTYIVTPSRDKEPVFEVTGMPENVDRAREEIEAHIALRTGGIIELTDENDFHANGTDVGFDLHHGSGGSGPGSLWSKPTPSITPTPGRKPFSSYRNDSSSSLGSASTDSYFGGGTSSSAAATQRLADYSPPSPALSFAHNGNNNNNGNGYTYTAGGEASVPSPDGCPELQPTFDPAPAPPPGAPLIWAQFERSPGGGPAAPVSSSCSSSASSSASSSSVVFPGGGASAPSNANLGLLVHRRLHPGTSCPRLSPPLHMAPGAGEHHLARRVRSDPGGGGLAYAAYANGLGAQLPGLQPSDTSGSSSSSSSSSSSSSSSSGLRRKGSRDCSVCFESEVIAALVPCGHNLFCMECANRICEKSEPECPVCHTAVTQAIRIFS

Target ORF information:

RefSeq Version	NM_032246.5
Organism	Homo sapiens(human)
Definition	Homo sapiens mex-3 RNA binding family member B (MEX3B), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_032246.5

ORF Insert Sequence:

ATGCCCAGCT CGCTGTTCGC AGACCTGGAG CGCAACGGCA GCGGCGGCGG CGGCGGCGGC 
AGCAGCGGAG GGGGAGAGAC CCTGGATGAC CAAAGAGCCC TGCAGCTCGC GCTCGACCAG 
CTCTCCCTGC TGGGGCTGGA CAGTGACGAG GGCGCCTCTC TGTACGACAG CGAGCCGCGC 
AAGAAGAGCG TGAACATGAC CGAGTGCGTG CCAGTACCCA GTTCTGAGCA TGTCGCCGAG 
ATCGTGGGGC GGCAAGGTTG TAAAATCAAA GCGCTGCGGG CGAAGACCAA TACTTACATC 
AAGACCCCAG TTCGCGGGGA GGAGCCTGTC TTTGTTGTGA CGGGCAGGAA GGAGGATGTG 
GCCATGGCTC GGAGGGAGAT CATCTCTGCT GCCGAGCACT TCTCCATGAT CCGCGCCTCC 
CGGAATAAGA ACACGGCACT CAACGGCGCG GTGCCTGGGC CGCCCAACCT GCCCGGGCAG 
ACCACCATCC AAGTGCGGGT ACCCTACCGC GTGGTGGGGC TCGTGGTGGG GCCCAAAGGC 
GCCACAATCA AGCGCATCCA GCAGCAGACG CACACGTACA TCGTGACGCC CAGCCGGGAT 
AAGGAGCCGG TGTTCGAGGT GACCGGCATG CCAGAGAACG TGGATCGCGC TCGAGAGGAG 
ATTGAGGCGC ACATTGCTCT GCGTACCGGC GGCATCATTG AGCTCACAGA CGAGAACGAC 
TTCCACGCCA ACGGCACCGA TGTGGGCTTC GATCTGCATC ATGGGTCCGG CGGGTCCGGC 
CCAGGCAGCC TCTGGAGCAA GCCCACCCCC AGCATCACGC CCACCCCCGG CCGCAAGCCT 
TTCTCTAGCT ACCGCAACGA CAGCTCCAGC TCGCTTGGCA GTGCTTCCAC AGACTCTTAT 
TTCGGCGGCG GGACCAGCAG CAGCGCAGCG GCTACCCAGC GCCTGGCGGA CTACAGCCCC 
CCTAGCCCCG CCCTGAGCTT TGCGCACAAC GGAAACAATA ACAATAACGG CAATGGGTAC 
ACCTACACAG CGGGGGGAGA AGCCTCAGTG CCATCCCCCG ACGGCTGCCC CGAGCTGCAG 
CCCACTTTTG ACCCGGCTCC CGCTCCCCCA CCTGGGGCAC CACTTATCTG GGCCCAGTTC 
GAGCGGTCCC CGGGAGGCGG ACCTGCAGCT CCGGTATCTT CTTCCTGCTC TTCTTCTGCA 
TCTTCGTCTG CTTCTTCCTC CTCCGTGGTC TTCCCCGGGG GTGGCGCCAG TGCGCCCTCC 
AACGCCAACC TGGGGCTATT GGTGCACCGC CGGCTGCACC CTGGCACCAG CTGCCCGCGC 
CTGTCTCCAC CCTTGCACAT GGCCCCGGGG GCGGGAGAGC ACCACCTGGC TCGCCGGGTG 
CGCAGCGACC CGGGTGGAGG AGGCCTGGCC TACGCCGCTT ATGCCAACGG GCTGGGGGCA 
CAGCTGCCTG GCTTGCAGCC GTCGGACACG TCGGGCTCCT CCTCTTCGTC CAGCTCCTCC 
TCCAGCTCTT CATCCTCTTC CTCCGGGCTT CGGCGTAAAG GCAGCCGCGA CTGCTCCGTG 
TGCTTCGAGA GCGAAGTGAT TGCCGCGCTG GTGCCCTGTG GCCACAACCT CTTCTGCATG 
GAGTGCGCCA ATCGCATCTG TGAGAAGAGC GAGCCCGAGT GCCCGGTCTG CCACACCGCG 
GTCACTCAGG CCATCCGCAT CTTTTCTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MEX3B ( NM_032246.6 ) cDNA ORF clone, Homo sapiens(human) -> NP_115622.2 Homo sapiens mex-3 RNA binding family member B (MEX3B), mRNA.

Price & Availability↑

CloneID	OHu00607
Clone ID Related Accession (Same CDS sequence)	NM_032246.5 , NM_032246.6 , NM_032246.4
Accession Version	NM_032246.6 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1710bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2020-01-04
Organism	Homo sapiens(human)
Product	RNA-binding protein MEX3B
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC026956.20. On Aug 31, 2019 this sequence version replaced NM_032246.5. ##Evidence-Data-START## Transcript exon combination :: AK131424.1, BC036211.1 [ECO:0000332] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000329713.5/ ENSP00000329918.4 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGCCCAGCT CGCTGTTCGC AGACCTGGAG CGCAACGGCA GCGGCGGCGG CGGCGGCGGC 
AGCAGCGGAG GGGGAGAGAC CCTGGATGAC CAAAGAGCCC TGCAGCTCGC GCTCGACCAG 
CTCTCCCTGC TGGGGCTGGA CAGTGACGAG GGCGCCTCTC TGTACGACAG CGAGCCGCGC 
AAGAAGAGCG TGAACATGAC CGAGTGCGTG CCAGTACCCA GTTCTGAGCA TGTCGCCGAG 
ATCGTGGGGC GGCAAGGTTG TAAAATCAAA GCGCTGCGGG CGAAGACCAA TACTTACATC 
AAGACCCCAG TTCGCGGGGA GGAGCCTGTC TTTGTTGTGA CGGGCAGGAA GGAGGATGTG 
GCCATGGCTC GGAGGGAGAT CATCTCTGCT GCCGAGCACT TCTCCATGAT CCGCGCCTCC 
CGGAATAAGA ACACGGCACT CAACGGCGCG GTGCCTGGGC CGCCCAACCT GCCCGGGCAG 
ACCACCATCC AAGTGCGGGT ACCCTACCGC GTGGTGGGGC TCGTGGTGGG GCCCAAAGGC 
GCCACAATCA AGCGCATCCA GCAGCAGACG CACACGTACA TCGTGACGCC CAGCCGGGAT 
AAGGAGCCGG TGTTCGAGGT GACCGGCATG CCAGAGAACG TGGATCGCGC TCGAGAGGAG 
ATTGAGGCGC ACATTGCTCT GCGTACCGGC GGCATCATTG AGCTCACAGA CGAGAACGAC 
TTCCACGCCA ACGGCACCGA TGTGGGCTTC GATCTGCATC ATGGGTCCGG CGGGTCCGGC 
CCAGGCAGCC TCTGGAGCAA GCCCACCCCC AGCATCACGC CCACCCCCGG CCGCAAGCCT 
TTCTCTAGCT ACCGCAACGA CAGCTCCAGC TCGCTTGGCA GTGCTTCCAC AGACTCTTAT 
TTCGGCGGCG GGACCAGCAG CAGCGCAGCG GCTACCCAGC GCCTGGCGGA CTACAGCCCC 
CCTAGCCCCG CCCTGAGCTT TGCGCACAAC GGAAACAATA ACAATAACGG CAATGGGTAC 
ACCTACACAG CGGGGGGAGA AGCCTCAGTG CCATCCCCCG ACGGCTGCCC CGAGCTGCAG 
CCCACTTTTG ACCCGGCTCC CGCTCCCCCA CCTGGGGCAC CACTTATCTG GGCCCAGTTC 
GAGCGGTCCC CGGGAGGCGG ACCTGCAGCT CCGGTATCTT CTTCCTGCTC TTCTTCTGCA 
TCTTCGTCTG CTTCTTCCTC CTCCGTGGTC TTCCCCGGGG GTGGCGCCAG TGCGCCCTCC 
AACGCCAACC TGGGGCTATT GGTGCACCGC CGGCTGCACC CTGGCACCAG CTGCCCGCGC 
CTGTCTCCAC CCTTGCACAT GGCCCCGGGG GCGGGAGAGC ACCACCTGGC TCGCCGGGTG 
CGCAGCGACC CGGGTGGAGG AGGCCTGGCC TACGCCGCTT ATGCCAACGG GCTGGGGGCA 
CAGCTGCCTG GCTTGCAGCC GTCGGACACG TCGGGCTCCT CCTCTTCGTC CAGCTCCTCC 
TCCAGCTCTT CATCCTCTTC CTCCGGGCTT CGGCGTAAAG GCAGCCGCGA CTGCTCCGTG 
TGCTTCGAGA GCGAAGTGAT TGCCGCGCTG GTGCCCTGTG GCCACAACCT CTTCTGCATG 
GAGTGCGCCA ATCGCATCTG TGAGAAGAGC GAGCCCGAGT GCCCGGTCTG CCACACCGCG 
GTCACTCAGG CCATCCGCAT CTTTTCTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_115622.2
CDS	314..2023
Translation	MPSSLFADLERNGSGGGGGGSSGGGETLDDQRALQLALDQLSLLGLDSDEGASLYDSEPRKKSVNMTECVPVPSSEHVAEIVGRQGCKIKALRAKTNTYIKTPVRGEEPVFVVTGRKEDVAMARREIISAAEHFSMIRASRNKNTALNGAVPGPPNLPGQTTIQVRVPYRVVGLVVGPKGATIKRIQQQTHTYIVTPSRDKEPVFEVTGMPENVDRAREEIEAHIALRTGGIIELTDENDFHANGTDVGFDLHHGSGGSGPGSLWSKPTPSITPTPGRKPFSSYRNDSSSSLGSASTDSYFGGGTSSSAAATQRLADYSPPSPALSFAHNGNNNNNGNGYTYTAGGEASVPSPDGCPELQPTFDPAPAPPPGAPLIWAQFERSPGGGPAAPVSSSCSSSASSSASSSSVVFPGGGASAPSNANLGLLVHRRLHPGTSCPRLSPPLHMAPGAGEHHLARRVRSDPGGGGLAYAAYANGLGAQLPGLQPSDTSGSSSSSSSSSSSSSSSSGLRRKGSRDCSVCFESEVIAALVPCGHNLFCMECANRICEKSEPECPVCHTAVTQAIRIFS

Target ORF information:

RefSeq Version	NM_032246.6
Organism	Homo sapiens(human)
Definition	Homo sapiens mex-3 RNA binding family member B (MEX3B), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_032246.6

ORF Insert Sequence:

ATGCCCAGCT CGCTGTTCGC AGACCTGGAG CGCAACGGCA GCGGCGGCGG CGGCGGCGGC 
AGCAGCGGAG GGGGAGAGAC CCTGGATGAC CAAAGAGCCC TGCAGCTCGC GCTCGACCAG 
CTCTCCCTGC TGGGGCTGGA CAGTGACGAG GGCGCCTCTC TGTACGACAG CGAGCCGCGC 
AAGAAGAGCG TGAACATGAC CGAGTGCGTG CCAGTACCCA GTTCTGAGCA TGTCGCCGAG 
ATCGTGGGGC GGCAAGGTTG TAAAATCAAA GCGCTGCGGG CGAAGACCAA TACTTACATC 
AAGACCCCAG TTCGCGGGGA GGAGCCTGTC TTTGTTGTGA CGGGCAGGAA GGAGGATGTG 
GCCATGGCTC GGAGGGAGAT CATCTCTGCT GCCGAGCACT TCTCCATGAT CCGCGCCTCC 
CGGAATAAGA ACACGGCACT CAACGGCGCG GTGCCTGGGC CGCCCAACCT GCCCGGGCAG 
ACCACCATCC AAGTGCGGGT ACCCTACCGC GTGGTGGGGC TCGTGGTGGG GCCCAAAGGC 
GCCACAATCA AGCGCATCCA GCAGCAGACG CACACGTACA TCGTGACGCC CAGCCGGGAT 
AAGGAGCCGG TGTTCGAGGT GACCGGCATG CCAGAGAACG TGGATCGCGC TCGAGAGGAG 
ATTGAGGCGC ACATTGCTCT GCGTACCGGC GGCATCATTG AGCTCACAGA CGAGAACGAC 
TTCCACGCCA ACGGCACCGA TGTGGGCTTC GATCTGCATC ATGGGTCCGG CGGGTCCGGC 
CCAGGCAGCC TCTGGAGCAA GCCCACCCCC AGCATCACGC CCACCCCCGG CCGCAAGCCT 
TTCTCTAGCT ACCGCAACGA CAGCTCCAGC TCGCTTGGCA GTGCTTCCAC AGACTCTTAT 
TTCGGCGGCG GGACCAGCAG CAGCGCAGCG GCTACCCAGC GCCTGGCGGA CTACAGCCCC 
CCTAGCCCCG CCCTGAGCTT TGCGCACAAC GGAAACAATA ACAATAACGG CAATGGGTAC 
ACCTACACAG CGGGGGGAGA AGCCTCAGTG CCATCCCCCG ACGGCTGCCC CGAGCTGCAG 
CCCACTTTTG ACCCGGCTCC CGCTCCCCCA CCTGGGGCAC CACTTATCTG GGCCCAGTTC 
GAGCGGTCCC CGGGAGGCGG ACCTGCAGCT CCGGTATCTT CTTCCTGCTC TTCTTCTGCA 
TCTTCGTCTG CTTCTTCCTC CTCCGTGGTC TTCCCCGGGG GTGGCGCCAG TGCGCCCTCC 
AACGCCAACC TGGGGCTATT GGTGCACCGC CGGCTGCACC CTGGCACCAG CTGCCCGCGC 
CTGTCTCCAC CCTTGCACAT GGCCCCGGGG GCGGGAGAGC ACCACCTGGC TCGCCGGGTG 
CGCAGCGACC CGGGTGGAGG AGGCCTGGCC TACGCCGCTT ATGCCAACGG GCTGGGGGCA 
CAGCTGCCTG GCTTGCAGCC GTCGGACACG TCGGGCTCCT CCTCTTCGTC CAGCTCCTCC 
TCCAGCTCTT CATCCTCTTC CTCCGGGCTT CGGCGTAAAG GCAGCCGCGA CTGCTCCGTG 
TGCTTCGAGA GCGAAGTGAT TGCCGCGCTG GTGCCCTGTG GCCACAACCT CTTCTGCATG 
GAGTGCGCCA ATCGCATCTG TGAGAAGAGC GAGCCCGAGT GCCCGGTCTG CCACACCGCG 
GTCACTCAGG CCATCCGCAT CTTTTCTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MEX3B ( NM_032246.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_115622.2 Homo sapiens mex-3 RNA binding family member B (MEX3B), mRNA.

Price & Availability↑

CloneID	OHu00607
Clone ID Related Accession (Same CDS sequence)	NM_032246.5 , NM_032246.6 , NM_032246.4
Accession Version	NM_032246.4	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1710bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-02
Organism	Homo sapiens(human)
Product	RNA-binding protein MEX3B
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from HY013949.1, BC036211.1, AK131424.1, BC111545.1, AB095929.1 and AA442153.1. On Oct 18, 2012 this sequence version replaced NM_032246.3. ##Evidence-Data-START## Transcript exon combination :: AK131424.1, BC036211.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCCCAGCT CGCTGTTCGC AGACCTGGAG CGCAACGGCA GCGGCGGCGG CGGCGGCGGC 
AGCAGCGGAG GGGGAGAGAC CCTGGATGAC CAAAGAGCCC TGCAGCTCGC GCTCGACCAG 
CTCTCCCTGC TGGGGCTGGA CAGTGACGAG GGCGCCTCTC TGTACGACAG CGAGCCGCGC 
AAGAAGAGCG TGAACATGAC CGAGTGCGTG CCAGTACCCA GTTCTGAGCA TGTCGCCGAG 
ATCGTGGGGC GGCAAGGTTG TAAAATCAAA GCGCTGCGGG CGAAGACCAA TACTTACATC 
AAGACCCCAG TTCGCGGGGA GGAGCCTGTC TTTGTTGTGA CGGGCAGGAA GGAGGATGTG 
GCCATGGCTC GGAGGGAGAT CATCTCTGCT GCCGAGCACT TCTCCATGAT CCGCGCCTCC 
CGGAATAAGA ACACGGCACT CAACGGCGCG GTGCCTGGGC CGCCCAACCT GCCCGGGCAG 
ACCACCATCC AAGTGCGGGT ACCCTACCGC GTGGTGGGGC TCGTGGTGGG GCCCAAAGGC 
GCCACAATCA AGCGCATCCA GCAGCAGACG CACACGTACA TCGTGACGCC CAGCCGGGAT 
AAGGAGCCGG TGTTCGAGGT GACCGGCATG CCAGAGAACG TGGATCGCGC TCGAGAGGAG 
ATTGAGGCGC ACATTGCTCT GCGTACCGGC GGCATCATTG AGCTCACAGA CGAGAACGAC 
TTCCACGCCA ACGGCACCGA TGTGGGCTTC GATCTGCATC ATGGGTCCGG CGGGTCCGGC 
CCAGGCAGCC TCTGGAGCAA GCCCACCCCC AGCATCACGC CCACCCCCGG CCGCAAGCCT 
TTCTCTAGCT ACCGCAACGA CAGCTCCAGC TCGCTTGGCA GTGCTTCCAC AGACTCTTAT 
TTCGGCGGCG GGACCAGCAG CAGCGCAGCG GCTACCCAGC GCCTGGCGGA CTACAGCCCC 
CCTAGCCCCG CCCTGAGCTT TGCGCACAAC GGAAACAATA ACAATAACGG CAATGGGTAC 
ACCTACACAG CGGGGGGAGA AGCCTCAGTG CCATCCCCCG ACGGCTGCCC CGAGCTGCAG 
CCCACTTTTG ACCCGGCTCC CGCTCCCCCA CCTGGGGCAC CACTTATCTG GGCCCAGTTC 
GAGCGGTCCC CGGGAGGCGG ACCTGCAGCT CCGGTATCTT CTTCCTGCTC TTCTTCTGCA 
TCTTCGTCTG CTTCTTCCTC CTCCGTGGTC TTCCCCGGGG GTGGCGCCAG TGCGCCCTCC 
AACGCCAACC TGGGGCTATT GGTGCACCGC CGGCTGCACC CTGGCACCAG CTGCCCGCGC 
CTGTCTCCAC CCTTGCACAT GGCCCCGGGG GCGGGAGAGC ACCACCTGGC TCGCCGGGTG 
CGCAGCGACC CGGGTGGAGG AGGCCTGGCC TACGCCGCTT ATGCCAACGG GCTGGGGGCA 
CAGCTGCCTG GCTTGCAGCC GTCGGACACG TCGGGCTCCT CCTCTTCGTC CAGCTCCTCC 
TCCAGCTCTT CATCCTCTTC CTCCGGGCTT CGGCGTAAAG GCAGCCGCGA CTGCTCCGTG 
TGCTTCGAGA GCGAAGTGAT TGCCGCGCTG GTGCCCTGTG GCCACAACCT CTTCTGCATG 
GAGTGCGCCA ATCGCATCTG TGAGAAGAGC GAGCCCGAGT GCCCGGTCTG CCACACCGCG 
GTCACTCAGG CCATCCGCAT CTTTTCTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_115622.2
CDS	439..2148
Translation	MPSSLFADLERNGSGGGGGGSSGGGETLDDQRALQLALDQLSLLGLDSDEGASLYDSEPRKKSVNMTECVPVPSSEHVAEIVGRQGCKIKALRAKTNTYIKTPVRGEEPVFVVTGRKEDVAMARREIISAAEHFSMIRASRNKNTALNGAVPGPPNLPGQTTIQVRVPYRVVGLVVGPKGATIKRIQQQTHTYIVTPSRDKEPVFEVTGMPENVDRAREEIEAHIALRTGGIIELTDENDFHANGTDVGFDLHHGSGGSGPGSLWSKPTPSITPTPGRKPFSSYRNDSSSSLGSASTDSYFGGGTSSSAAATQRLADYSPPSPALSFAHNGNNNNNGNGYTYTAGGEASVPSPDGCPELQPTFDPAPAPPPGAPLIWAQFERSPGGGPAAPVSSSCSSSASSSASSSSVVFPGGGASAPSNANLGLLVHRRLHPGTSCPRLSPPLHMAPGAGEHHLARRVRSDPGGGGLAYAAYANGLGAQLPGLQPSDTSGSSSSSSSSSSSSSSSSGLRRKGSRDCSVCFESEVIAALVPCGHNLFCMECANRICEKSEPECPVCHTAVTQAIRIFS

Target ORF information:

RefSeq Version	NM_032246.4
Organism	Homo sapiens(human)
Definition	Homo sapiens mex-3 RNA binding family member B (MEX3B), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_032246.4

ORF Insert Sequence:

ATGCCCAGCT CGCTGTTCGC AGACCTGGAG CGCAACGGCA GCGGCGGCGG CGGCGGCGGC 
AGCAGCGGAG GGGGAGAGAC CCTGGATGAC CAAAGAGCCC TGCAGCTCGC GCTCGACCAG 
CTCTCCCTGC TGGGGCTGGA CAGTGACGAG GGCGCCTCTC TGTACGACAG CGAGCCGCGC 
AAGAAGAGCG TGAACATGAC CGAGTGCGTG CCAGTACCCA GTTCTGAGCA TGTCGCCGAG 
ATCGTGGGGC GGCAAGGTTG TAAAATCAAA GCGCTGCGGG CGAAGACCAA TACTTACATC 
AAGACCCCAG TTCGCGGGGA GGAGCCTGTC TTTGTTGTGA CGGGCAGGAA GGAGGATGTG 
GCCATGGCTC GGAGGGAGAT CATCTCTGCT GCCGAGCACT TCTCCATGAT CCGCGCCTCC 
CGGAATAAGA ACACGGCACT CAACGGCGCG GTGCCTGGGC CGCCCAACCT GCCCGGGCAG 
ACCACCATCC AAGTGCGGGT ACCCTACCGC GTGGTGGGGC TCGTGGTGGG GCCCAAAGGC 
GCCACAATCA AGCGCATCCA GCAGCAGACG CACACGTACA TCGTGACGCC CAGCCGGGAT 
AAGGAGCCGG TGTTCGAGGT GACCGGCATG CCAGAGAACG TGGATCGCGC TCGAGAGGAG 
ATTGAGGCGC ACATTGCTCT GCGTACCGGC GGCATCATTG AGCTCACAGA CGAGAACGAC 
TTCCACGCCA ACGGCACCGA TGTGGGCTTC GATCTGCATC ATGGGTCCGG CGGGTCCGGC 
CCAGGCAGCC TCTGGAGCAA GCCCACCCCC AGCATCACGC CCACCCCCGG CCGCAAGCCT 
TTCTCTAGCT ACCGCAACGA CAGCTCCAGC TCGCTTGGCA GTGCTTCCAC AGACTCTTAT 
TTCGGCGGCG GGACCAGCAG CAGCGCAGCG GCTACCCAGC GCCTGGCGGA CTACAGCCCC 
CCTAGCCCCG CCCTGAGCTT TGCGCACAAC GGAAACAATA ACAATAACGG CAATGGGTAC 
ACCTACACAG CGGGGGGAGA AGCCTCAGTG CCATCCCCCG ACGGCTGCCC CGAGCTGCAG 
CCCACTTTTG ACCCGGCTCC CGCTCCCCCA CCTGGGGCAC CACTTATCTG GGCCCAGTTC 
GAGCGGTCCC CGGGAGGCGG ACCTGCAGCT CCGGTATCTT CTTCCTGCTC TTCTTCTGCA 
TCTTCGTCTG CTTCTTCCTC CTCCGTGGTC TTCCCCGGGG GTGGCGCCAG TGCGCCCTCC 
AACGCCAACC TGGGGCTATT GGTGCACCGC CGGCTGCACC CTGGCACCAG CTGCCCGCGC 
CTGTCTCCAC CCTTGCACAT GGCCCCGGGG GCGGGAGAGC ACCACCTGGC TCGCCGGGTG 
CGCAGCGACC CGGGTGGAGG AGGCCTGGCC TACGCCGCTT ATGCCAACGG GCTGGGGGCA 
CAGCTGCCTG GCTTGCAGCC GTCGGACACG TCGGGCTCCT CCTCTTCGTC CAGCTCCTCC 
TCCAGCTCTT CATCCTCTTC CTCCGGGCTT CGGCGTAAAG GCAGCCGCGA CTGCTCCGTG 
TGCTTCGAGA GCGAAGTGAT TGCCGCGCTG GTGCCCTGTG GCCACAACCT CTTCTGCATG 
GAGTGCGCCA ATCGCATCTG TGAGAAGAGC GAGCCCGAGT GCCCGGTCTG CCACACCGCG 
GTCACTCAGG CCATCCGCAT CTTTTCTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

A genome-wide association study of clinical symptoms of dissociation in a trauma-exposed sample.
Depression and anxiety31(4)352-60(2014 Apr)
Wolf EJ,Rasmusson AM,Mitchell KS,Logue MW,Baldwin CT,Miller MW

The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.
Molecular cell46(5)674-90(2012 Jun)
Baltz AG,Munschauer M,Schwanh?usser B,Vasile A,Murakawa Y,Schueler M,Youngs N,Penfold-Brown D,Drew K,Milek M,Wyler E,Bonneau R,Selbach M,Dieterich C,Landthaler M

Six new loci associated with body mass index highlight a neuronal influence on body weight regulation.
Nature genetics41(1)25-34(2009 Jan)
Willer CJ,Speliotes EK,Loos RJ,Li S,Lindgren CM,Heid IM,Berndt SI,Elliott AL,Jackson AU,Lamina C,Lettre G,Lim N,Lyon HN,McCarroll SA,Papadakis K,Qi L,Randall JC,Roccasecca RM,Sanna S,Scheet P,Weedon MN,Wheeler E,Zhao JH,Jacobs LC,Prokopenko I,Soranzo N,Tanaka T,Timpson NJ,Almgren P,Bennett A,Bergman RN,Bingham SA,Bonnycastle LL,Brown M,Burtt NP,Chines P,Coin L,Collins FS,Connell JM,Cooper C,Smith GD,Dennison EM,Deodhar P,Elliott P,Erdos MR,Estrada K,Evans DM,Gianniny L,Gieger C,Gillson CJ,Guiducci C,Hackett R,Hadley D,Hall AS,Havulinna AS,Hebebrand J,Hofman A,Isomaa B,Jacobs KB,Johnson T,Jousilahti P,Jovanovic Z,Khaw KT,Kraft P,Kuokkanen M,Kuusisto J,Laitinen J,Lakatta EG,Luan J,Luben RN,Mangino M,McArdle WL,Meitinger T,Mulas A,Munroe PB,Narisu N,Ness AR,Northstone K,O'Rahilly S,Purmann C,Rees MG,Ridderstr?le M,Ring SM,Rivadeneira F,Ruokonen A,Sandhu MS,Saramies J,Scott LJ,Scuteri A,Silander K,Sims MA,Song K,Stephens J,Stevens S,Stringham HM,Tung YC,Valle TT,Van Duijn CM,Vimaleswaran KS,Vollenweider P,Waeber G,Wallace C,Watanabe RM,Waterworth DM,Watkins N,,Witteman JC,Zeggini E,Zhai G,Zillikens MC,Altshuler D,Caulfield MJ,Chanock SJ,Farooqi IS,Ferrucci L,Guralnik JM,Hattersley AT,Hu FB,Jarvelin MR,Laakso M,Mooser V,Ong KK,Ouwehand WH,Salomaa V,Samani NJ,Spector TD,Tuomi T,Tuomilehto J,Uda M,Uitterlinden AG,Wareham NJ,Deloukas P,Frayling TM,Groop LC,Hayes RB,Hunter DJ,Mohlke KL,Peltonen L,Schlessinger D,Strachan DP,Wichmann HE,McCarthy MI,Boehnke M,Barroso I,Abecasis GR,Hirschhorn JN,

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MEX3B cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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