TXNDC2 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	TXNDC2
Entrez Gene ID	84203
Full Name	thioredoxin domain containing 2
Synonyms	SPTRX,SPTRX1
General protein information	Preferred Names thioredoxin domain containing 2 Names thioredoxin domain-containing protein 2 sperm-specific thioredoxin 1 spermatid-specific thioredoxin-1 sptrx-1 testicular tissue protein Li 215 thioredoxin domain containing 2 (spermatozoa)
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 18 Map Location: 18p11.22
Disorder MIM:	617790

mRNA and Protein(s)

mRNA	Protein	Name
NM_001098529.2	NP_001091999.1	thioredoxin domain-containing protein 2 isoform 2
NM_001098529.1	NP_001091999.1	thioredoxin domain-containing protein 2 isoform 2
NM_032243.5	NP_115619.4	thioredoxin domain-containing protein 2 isoform 1
XM_017026041.1	XP_016881530.1	thioredoxin domain-containing protein 2 isoform X1
NM_032243.6	NP_115619.4	thioredoxin domain-containing protein 2 isoform 1

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	TXNDC2	XP_001135716.1
Bos taurus (cattle)	TXNDC2	XP_005224361.1
Rattus norvegicus (Norway rat)	Txndc2	NP_001139476.1
Mus musculus (house mouse)	Txndc2	NP_705739.2
Canis lupus familiaris (dog)	TXNDC2	XP_005623141.1
Homo sapiens (human)	TXNDC2	NP_001091999.1

Gene Ontology
Bibliography

Related articles in PubMed

Genome-wide joint meta-analysis of SNP and SNP-by-smoking interaction identifies novel loci for pulmonary function.
Hancock DB, Soler Artigas M, Gharib SA, Henry A, Manichaikul A, Ramasamy A, Loth DW, Imboden M, Koch B, McArdle WL, Smith AV, Smolonska J, Sood A, Tang W, Wilk JB, Zhai G, Zhao JH, Aschard H, Burkart KM, Curjuric I, Eijgelsheim M, Elliott P, Gu X, Harris TB, Janson C, Homuth G, Hysi PG, Liu JZ, Loehr LR, Lohman K, Loos RJ, Manning AK, Marciante KD, Obeidat M, Postma DS, Aldrich MC, Brusselle GG, Chen TH, Eiriksdottir G, Franceschini N, Heinrich J, Rotter JI, Wijmenga C, Williams OD, Bentley AR, Hofman A, Laurie CC, Lumley T, Morrison AC, Joubert BR, Rivadeneira F, Couper DJ, Kritchevsky SB, Liu Y, Wjst M, Wain LV, Vonk JM, Uitterlinden AG, Rochat T, Rich SS, Psaty BM, O'Connor GT, North KE, Mirel DB, Meibohm B, Launer LJ, Khaw KT, Hartikainen AL, Hammond CJ, Gl?ser S, Marchini J, Kraft P, Wareham NJ, V?lzke H, Stricker BH, Spector TD, Probst-Hensch NM, Jarvis D, Jarvelin MR, Heckbert SR, Gudnason V, Boezen HM, Barr RG, Cassano PA, Strachan DP, Fornage M, Hall IP, Dupuis J, Tobin MD, London SJ
PLoS genetics8(12)e1003098(2012)

Is serum thioredoxin-1 a useful clinical marker for malignant pleural mesothelioma?
Maeda R, Tabata C, Tabata R, Eguchi R, Fujimori Y, Nakano T
Antioxidants & redox signaling15(3)685-9(2011 Aug)

Human spermatid-specific thioredoxin-1 (Sptrx-1) is a two-domain protein with oxidizing activity.
Jim?nez A, Johansson C, Ljung J, Sagemark J, Berndt KD, Ren B, Tibbelin G, Ladenstein R, Kieselbach T, Holmgren A, Gustafsson JA, Miranda-Vizuete A
FEBS letters530(1-3)79-84(2002 Oct)

Sptrx-2, a fusion protein composed of one thioredoxin and three tandemly repeated NDP-kinase domains is expressed in human testis germ cells.
Sadek CM, Damdimopoulos AE, Pelto-Huikko M, Gustafsson JA, Spyrou G, Miranda-Vizuete A
Genes to cells : devoted to molecular & cellular mechanisms6(12)1077-90(2001 Dec)

Characterization of Sptrx, a novel member of the thioredoxin family specifically expressed in human spermatozoa.
Miranda-Vizuete A, Ljung J, Damdimopoulos AE, Gustafsson JA, Oko R, Pelto-Huikko M, Spyrou G
The Journal of biological chemistry276(34)31567-74(2001 Aug)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The patients with advanced-stagemalignant pleural mesothelioma (MPM) showed higher levels of TRX than those with early-stage MPM.
Title: Is serum thioredoxin-1 a useful clinical marker for malignant pleural mesothelioma?

spermatid-specific thioredoxin-1 (Sptrx-1) is a two-domain protein with oxidizing activity
Title: Human spermatid-specific thioredoxin-1 (Sptrx-1) is a two-domain protein with oxidizing activity.

sperm specific expression, together with chromosomal assignment to a position as a potential locus for flagellar anomalies and male infertility phenotypes, suggests that it might be a novel component of the human sperm axonemal organization.
Title: Sptrx-2, a fusion protein composed of one thioredoxin and three tandemly repeated NDP-kinase domains is expressed in human testis germ cells.

The following TXNDC2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the TXNDC2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu32347	NM_032243.6 Latest version!	Homo sapiens thioredoxin domain containing 2 (TXNDC2), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$265.30 $379.00
OHu55604	NM_001098529.2 Latest version!	Homo sapiens thioredoxin domain containing 2 (TXNDC2), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$321.30 $459.00
OHu32347	XM_017026041.1 Latest version!	Homo sapiens thioredoxin domain containing 2 (TXNDC2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$265.30 $379.00
View Old Accession Versions >>
OHu55604	NM_001098529.1	Homo sapiens thioredoxin domain containing 2 (TXNDC2), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$321.30 $459.00
OHu32347	NM_032243.5	Homo sapiens thioredoxin domain containing 2 (TXNDC2), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$265.30 $379.00
Hide Old Accession Versions >>

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

TXNDC2 ( NM_032243.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_115619.4 Homo sapiens thioredoxin domain containing 2 (TXNDC2), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu32347
Clone ID Related Accession (Same CDS sequence)	NM_032243.5 , XM_017026041.1 , NM_032243.6
Accession Version	NM_032243.5	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1461bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-06-22
Organism	Homo sapiens(human)
Product	thioredoxin domain-containing protein 2 isoform 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DB032859.1, BC050132.1 and AF080095.1. On or before Jul 17, 2010 this sequence version replaced NM_001098530.1, XM_001721367.1, XM_001721366.1, NM_032243.4. Transcript Variant: This variant (1) encodes the predominant protein (isoform 1) and represents the variant originally described in PMID: 11399755. ##Evidence-Data-START## Transcript exon combination :: BC050132.1, AF080095.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA2142670 [ECO:0000348] ##Evidence-Data-END##

ATGGTCAGCC ACACGTTCCA CATGCGCACA GAGGAGTCTG ATGCCTCACA GGAGGGCGAT 
GACCTACCCA AGTCCTCAGC AAACACCAGC CATCCCAAGC AGGATGACAG CCCCAAGTCC 
TCAGAAGAAA CCATCCAGCC CAAGGAGGGT GACATCCCCA AGGCCCCAGA AGAAACCATC 
CAATCCAAGA AGGAGGACCT CCCCAAGTCC TCAGAAAAAG CCATCCAGCC CAAAGAGAGT 
AACATCCCCA AGTCCTCAGC AAAACCCATC CAGCCCAAGC TGGGCAATAT TCCCAAGGCC 
TCAGTGAAGC CCAGCCAGCC CAAGGAGGGT GACATCCCCA AGGCCCCAGA AGAAACCATC 
CAATCCAAGA AGGAGGACCT CCCCAAGTCC TCAGAAGAAG CCATCCAGCC CAAAGAGGGT 
GACATCCCCA AGTCCTCAGC AAAACCCATC CAGCCCAAGC TGGGCAATAT TGCCAAGACC 
TCAGTGAAGC CCAGCCAGCC CAAGGAGAGT GATATCCCCA AGTCCCCAGA AGAAACCATC 
CAGCCCAAGG AGGGTGACAT CCCCAAGTCC TCAGCAAAGC CCATCCAGCC CAAGCTGGGC 
AATATTCCCA AGGCCTCAGT GAAGCCCAGC CAGCCCAAGG AGGGTGACAT CTCCAAGTCC 
CCAGAAGAAG CCATCCAGCC CAAGGAGGGT GACCTCCCCA AGTCCCTAGA GGAAGCCATC 
CAGCCCAAGG AGGGTGACAT CCCCAAGTCC CCAGAAGAAG CCATCCAGCC CAAGGAGGGT 
GACATCCCCA AGTCCCTAGA GGAAGCCATC CAGCCTAAGG AGGGTGACAT CCCCAAGTCC 
CCAGAAGAAA CCATCCAGCC CAAGAAGGGT GACATCCCCA AGTCCCCAGA AGAAGCCATC 
CAGCCCAAGG AGGGTGACAT TCCCAAGTCT CCAAAACAAG CCATCCAGCC CAAGGAGGGT 
GACATTCCCA AGTCCCTAGA GGAAGCCATC CCACCCAAGG AGATTGACAT CCCCAAGTCC 
CCAGAAGAAA CCATCCAGCC CAAGGAGGAT GACAGCCCCA AGTCCCTAGA AGAAGCCACC 
CCATCCAAGG AGGGTGACAT CCTAAAGCCT GAAGAAGAAA CAATGGAGTT CCCGGAGGGG 
GACAAGGTGA AAGTGATCCT GAGCAAGGAG GACTTTGAGG CATCACTGAA GGAGGCCGGG 
GAGAGGCTGG TGGCTGTGGA CTTCTCGGCC ACGTGGTGTG GGCCCTGCAG GACCATCAGA 
CCATTCTTCC ATGCCCTGTC TGTGAAGCAT GAGGATGTGG TGTTCCTGGA GGTGGACGCT 
GACAACTGTG AGGAGGTGGT GAGAGAGTGC GCCATCATGT GTGTCCCAAC CTTTCAGTTT 
TATAAAAAAG AAGAAAAGGT GGATGAACTT TGCGGCGCCC TTAAGGAAAA ACTTGAAGCA 
GTCATTGCAG AATTAAAGTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_115619.4
CDS	448..1908
Translation	MVSHTFHMRTEESDASQEGDDLPKSSANTSHPKQDDSPKSSEETIQPKEGDIPKAPEETIQSKKEDLPKSSEKAIQPKESNIPKSSAKPIQPKLGNIPKASVKPSQPKEGDIPKAPEETIQSKKEDLPKSSEEAIQPKEGDIPKSSAKPIQPKLGNIAKTSVKPSQPKESDIPKSPEETIQPKEGDIPKSSAKPIQPKLGNIPKASVKPSQPKEGDISKSPEEAIQPKEGDLPKSLEEAIQPKEGDIPKSPEEAIQPKEGDIPKSLEEAIQPKEGDIPKSPEETIQPKKGDIPKSPEEAIQPKEGDIPKSPKQAIQPKEGDIPKSLEEAIPPKEIDIPKSPEETIQPKEDDSPKSLEEATPSKEGDILKPEEETMEFPEGDKVKVILSKEDFEASLKEAGERLVAVDFSATWCGPCRTIRPFFHALSVKHEDVVFLEVDADNCEEVVRECAIMCVPTFQFYKKEEKVDELCGALKEKLEAVIAELK

Target ORF information:

RefSeq Version	NM_032243.5
Organism	Homo sapiens(human)
Definition	Homo sapiens thioredoxin domain containing 2 (TXNDC2), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_032243.5

ORF Insert Sequence:

ATGGTCAGCC ACACGTTCCA CATGCGCACA GAGGAGTCTG ATGCCTCACA GGAGGGCGAT 
GACCTACCCA AGTCCTCAGC AAACACCAGC CATCCCAAGC AGGATGACAG CCCCAAGTCC 
TCAGAAGAAA CCATCCAGCC CAAGGAGGGT GACATCCCCA AGGCCCCAGA AGAAACCATC 
CAATCCAAGA AGGAGGACCT CCCCAAGTCC TCAGAAAAAG CCATCCAGCC CAAAGAGAGT 
AACATCCCCA AGTCCTCAGC AAAACCCATC CAGCCCAAGC TGGGCAATAT TCCCAAGGCC 
TCAGTGAAGC CCAGCCAGCC CAAGGAGGGT GACATCCCCA AGGCCCCAGA AGAAACCATC 
CAATCCAAGA AGGAGGACCT CCCCAAGTCC TCAGAAGAAG CCATCCAGCC CAAAGAGGGT 
GACATCCCCA AGTCCTCAGC AAAACCCATC CAGCCCAAGC TGGGCAATAT TGCCAAGACC 
TCAGTGAAGC CCAGCCAGCC CAAGGAGAGT GATATCCCCA AGTCCCCAGA AGAAACCATC 
CAGCCCAAGG AGGGTGACAT CCCCAAGTCC TCAGCAAAGC CCATCCAGCC CAAGCTGGGC 
AATATTCCCA AGGCCTCAGT GAAGCCCAGC CAGCCCAAGG AGGGTGACAT CTCCAAGTCC 
CCAGAAGAAG CCATCCAGCC CAAGGAGGGT GACCTCCCCA AGTCCCTAGA GGAAGCCATC 
CAGCCCAAGG AGGGTGACAT CCCCAAGTCC CCAGAAGAAG CCATCCAGCC CAAGGAGGGT 
GACATCCCCA AGTCCCTAGA GGAAGCCATC CAGCCTAAGG AGGGTGACAT CCCCAAGTCC 
CCAGAAGAAA CCATCCAGCC CAAGAAGGGT GACATCCCCA AGTCCCCAGA AGAAGCCATC 
CAGCCCAAGG AGGGTGACAT TCCCAAGTCT CCAAAACAAG CCATCCAGCC CAAGGAGGGT 
GACATTCCCA AGTCCCTAGA GGAAGCCATC CCACCCAAGG AGATTGACAT CCCCAAGTCC 
CCAGAAGAAA CCATCCAGCC CAAGGAGGAT GACAGCCCCA AGTCCCTAGA AGAAGCCACC 
CCATCCAAGG AGGGTGACAT CCTAAAGCCT GAAGAAGAAA CAATGGAGTT CCCGGAGGGG 
GACAAGGTGA AAGTGATCCT GAGCAAGGAG GACTTTGAGG CATCACTGAA GGAGGCCGGG 
GAGAGGCTGG TGGCTGTGGA CTTCTCGGCC ACGTGGTGTG GGCCCTGCAG GACCATCAGA 
CCATTCTTCC ATGCCCTGTC TGTGAAGCAT GAGGATGTGG TGTTCCTGGA GGTGGACGCT 
GACAACTGTG AGGAGGTGGT GAGAGAGTGC GCCATCATGT GTGTCCCAAC CTTTCAGTTT 
TATAAAAAAG AAGAAAAGGT GGATGAACTT TGCGGCGCCC TTAAGGAAAA ACTTGAAGCA 
GTCATTGCAG AATTAAAGTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TXNDC2 ( NM_032243.6 ) cDNA ORF clone, Homo sapiens(human) -> NP_115619.4 Homo sapiens thioredoxin domain containing 2 (TXNDC2), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu32347
Clone ID Related Accession (Same CDS sequence)	NM_032243.5 , XM_017026041.1 , NM_032243.6
Accession Version	NM_032243.6 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1461bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-18
Organism	Homo sapiens(human)
Product	thioredoxin domain-containing protein 2 isoform 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BC050132.1, AF080095.1 and AC006238.1. On May 17, 2019 this sequence version replaced NM_032243.5. Transcript Variant: This variant (1) encodes the predominant protein (isoform 1) and represents the variant originally described in PMID: 11399755. ##Evidence-Data-START## Transcript exon combination :: AF080095.1, BC050132.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA2142670 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000357775.6/ ENSP00000350419.4 RefSeq Select criteria :: based on expression ##RefSeq-Attributes-END##

ATGGTCAGCC ACACGTTCCA CATGCGCACA GAGGAGTCTG ATGCCTCACA GGAGGGCGAT 
GACCTACCCA AGTCCTCAGC AAACACCAGC CATCCCAAGC AGGATGACAG CCCCAAGTCC 
TCAGAAGAAA CCATCCAGCC CAAGGAGGGT GACATCCCCA AGGCCCCAGA AGAAACCATC 
CAATCCAAGA AGGAGGACCT CCCCAAGTCC TCAGAAAAAG CCATCCAGCC CAAAGAGAGT 
AACATCCCCA AGTCCTCAGC AAAACCCATC CAGCCCAAGC TGGGCAATAT TCCCAAGGCC 
TCAGTGAAGC CCAGCCAGCC CAAGGAGGGT GACATCCCCA AGGCCCCAGA AGAAACCATC 
CAATCCAAGA AGGAGGACCT CCCCAAGTCC TCAGAAGAAG CCATCCAGCC CAAAGAGGGT 
GACATCCCCA AGTCCTCAGC AAAACCCATC CAGCCCAAGC TGGGCAATAT TGCCAAGACC 
TCAGTGAAGC CCAGCCAGCC CAAGGAGAGT GATATCCCCA AGTCCCCAGA AGAAACCATC 
CAGCCCAAGG AGGGTGACAT CCCCAAGTCC TCAGCAAAGC CCATCCAGCC CAAGCTGGGC 
AATATTCCCA AGGCCTCAGT GAAGCCCAGC CAGCCCAAGG AGGGTGACAT CTCCAAGTCC 
CCAGAAGAAG CCATCCAGCC CAAGGAGGGT GACCTCCCCA AGTCCCTAGA GGAAGCCATC 
CAGCCCAAGG AGGGTGACAT CCCCAAGTCC CCAGAAGAAG CCATCCAGCC CAAGGAGGGT 
GACATCCCCA AGTCCCTAGA GGAAGCCATC CAGCCTAAGG AGGGTGACAT CCCCAAGTCC 
CCAGAAGAAA CCATCCAGCC CAAGAAGGGT GACATCCCCA AGTCCCCAGA AGAAGCCATC 
CAGCCCAAGG AGGGTGACAT TCCCAAGTCT CCAAAACAAG CCATCCAGCC CAAGGAGGGT 
GACATTCCCA AGTCCCTAGA GGAAGCCATC CCACCCAAGG AGATTGACAT CCCCAAGTCC 
CCAGAAGAAA CCATCCAGCC CAAGGAGGAT GACAGCCCCA AGTCCCTAGA AGAAGCCACC 
CCATCCAAGG AGGGTGACAT CCTAAAGCCT GAAGAAGAAA CAATGGAGTT CCCGGAGGGG 
GACAAGGTGA AAGTGATCCT GAGCAAGGAG GACTTTGAGG CATCACTGAA GGAGGCCGGG 
GAGAGGCTGG TGGCTGTGGA CTTCTCGGCC ACGTGGTGTG GGCCCTGCAG GACCATCAGA 
CCATTCTTCC ATGCCCTGTC TGTGAAGCAT GAGGATGTGG TGTTCCTGGA GGTGGACGCT 
GACAACTGTG AGGAGGTGGT GAGAGAGTGC GCCATCATGT GTGTCCCAAC CTTTCAGTTT 
TATAAAAAAG AAGAAAAGGT GGATGAACTT TGCGGCGCCC TTAAGGAAAA ACTTGAAGCA 
GTCATTGCAG AATTAAAGTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_115619.4
CDS	201..1661
Translation	MVSHTFHMRTEESDASQEGDDLPKSSANTSHPKQDDSPKSSEETIQPKEGDIPKAPEETIQSKKEDLPKSSEKAIQPKESNIPKSSAKPIQPKLGNIPKASVKPSQPKEGDIPKAPEETIQSKKEDLPKSSEEAIQPKEGDIPKSSAKPIQPKLGNIAKTSVKPSQPKESDIPKSPEETIQPKEGDIPKSSAKPIQPKLGNIPKASVKPSQPKEGDISKSPEEAIQPKEGDLPKSLEEAIQPKEGDIPKSPEEAIQPKEGDIPKSLEEAIQPKEGDIPKSPEETIQPKKGDIPKSPEEAIQPKEGDIPKSPKQAIQPKEGDIPKSLEEAIPPKEIDIPKSPEETIQPKEDDSPKSLEEATPSKEGDILKPEEETMEFPEGDKVKVILSKEDFEASLKEAGERLVAVDFSATWCGPCRTIRPFFHALSVKHEDVVFLEVDADNCEEVVRECAIMCVPTFQFYKKEEKVDELCGALKEKLEAVIAELK

Target ORF information:

RefSeq Version	NM_032243.6
Organism	Homo sapiens(human)
Definition	Homo sapiens thioredoxin domain containing 2 (TXNDC2), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_032243.6

ORF Insert Sequence:

ATGGTCAGCC ACACGTTCCA CATGCGCACA GAGGAGTCTG ATGCCTCACA GGAGGGCGAT 
GACCTACCCA AGTCCTCAGC AAACACCAGC CATCCCAAGC AGGATGACAG CCCCAAGTCC 
TCAGAAGAAA CCATCCAGCC CAAGGAGGGT GACATCCCCA AGGCCCCAGA AGAAACCATC 
CAATCCAAGA AGGAGGACCT CCCCAAGTCC TCAGAAAAAG CCATCCAGCC CAAAGAGAGT 
AACATCCCCA AGTCCTCAGC AAAACCCATC CAGCCCAAGC TGGGCAATAT TCCCAAGGCC 
TCAGTGAAGC CCAGCCAGCC CAAGGAGGGT GACATCCCCA AGGCCCCAGA AGAAACCATC 
CAATCCAAGA AGGAGGACCT CCCCAAGTCC TCAGAAGAAG CCATCCAGCC CAAAGAGGGT 
GACATCCCCA AGTCCTCAGC AAAACCCATC CAGCCCAAGC TGGGCAATAT TGCCAAGACC 
TCAGTGAAGC CCAGCCAGCC CAAGGAGAGT GATATCCCCA AGTCCCCAGA AGAAACCATC 
CAGCCCAAGG AGGGTGACAT CCCCAAGTCC TCAGCAAAGC CCATCCAGCC CAAGCTGGGC 
AATATTCCCA AGGCCTCAGT GAAGCCCAGC CAGCCCAAGG AGGGTGACAT CTCCAAGTCC 
CCAGAAGAAG CCATCCAGCC CAAGGAGGGT GACCTCCCCA AGTCCCTAGA GGAAGCCATC 
CAGCCCAAGG AGGGTGACAT CCCCAAGTCC CCAGAAGAAG CCATCCAGCC CAAGGAGGGT 
GACATCCCCA AGTCCCTAGA GGAAGCCATC CAGCCTAAGG AGGGTGACAT CCCCAAGTCC 
CCAGAAGAAA CCATCCAGCC CAAGAAGGGT GACATCCCCA AGTCCCCAGA AGAAGCCATC 
CAGCCCAAGG AGGGTGACAT TCCCAAGTCT CCAAAACAAG CCATCCAGCC CAAGGAGGGT 
GACATTCCCA AGTCCCTAGA GGAAGCCATC CCACCCAAGG AGATTGACAT CCCCAAGTCC 
CCAGAAGAAA CCATCCAGCC CAAGGAGGAT GACAGCCCCA AGTCCCTAGA AGAAGCCACC 
CCATCCAAGG AGGGTGACAT CCTAAAGCCT GAAGAAGAAA CAATGGAGTT CCCGGAGGGG 
GACAAGGTGA AAGTGATCCT GAGCAAGGAG GACTTTGAGG CATCACTGAA GGAGGCCGGG 
GAGAGGCTGG TGGCTGTGGA CTTCTCGGCC ACGTGGTGTG GGCCCTGCAG GACCATCAGA 
CCATTCTTCC ATGCCCTGTC TGTGAAGCAT GAGGATGTGG TGTTCCTGGA GGTGGACGCT 
GACAACTGTG AGGAGGTGGT GAGAGAGTGC GCCATCATGT GTGTCCCAAC CTTTCAGTTT 
TATAAAAAAG AAGAAAAGGT GGATGAACTT TGCGGCGCCC TTAAGGAAAA ACTTGAAGCA 
GTCATTGCAG AATTAAAGTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TXNDC2 ( NM_001098529.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001091999.1 Homo sapiens thioredoxin domain containing 2 (TXNDC2), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu55604
Clone ID Related Accession (Same CDS sequence)	NM_001098529.2 , NM_001098529.1
Accession Version	NM_001098529.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1662bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-17
Organism	Homo sapiens(human)
Product	thioredoxin domain-containing protein 2 isoform 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DB032859.1, AK097656.1, AF080095.1, BC050132.1 and AC006238.1. On May 31, 2019 this sequence version replaced NM_001098529.1. Transcript Variant: This variant (2) uses a different splice site, resulting in a longer open reading frame through the use of an upstream start codon, compared to variant 1. The predicted protein (isoform 2) has a longer N-terminus compared to isoform 1. ##Evidence-Data-START## Transcript exon combination :: AK097656.1, HM005528.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA2148093 [ECO:0000348] ##Evidence-Data-END##

ATGGATGTAG ACAAGGAACT AGGAATGGAA AGTGTTAAAG CTGGAGCCTC TGGAAAACCA 
GAAATGAGGC TGGGCACTCA GGAAGAAACA AGTGAAGGTG ATGCTAATGA AAGCTCATTA 
CTAGTCCTGT CCAGCAACGT GCCTCTCCTG GCCCTAGAGT TCTTGGAAAT AGCCCAGGCC 
AAAGAGAAGG CCTTTCTCCC CATGGTCAGC CACACGTTCC ACATGCGCAC AGAGGAGTCT 
GATGCCTCAC AGGAGGGCGA TGACCTACCC AAGTCCTCAG CAAACACCAG CCATCCCAAG 
CAGGATGACA GCCCCAAGTC CTCAGAAGAA ACCATCCAGC CCAAGGAGGG TGACATCCCC 
AAGGCCCCAG AAGAAACCAT CCAATCCAAG AAGGAGGACC TCCCCAAGTC CTCAGAAAAA 
GCCATCCAGC CCAAAGAGAG TAACATCCCC AAGTCCTCAG CAAAACCCAT CCAGCCCAAG 
CTGGGCAATA TTCCCAAGGC CTCAGTGAAG CCCAGCCAGC CCAAGGAGGG TGACATCCCC 
AAGGCCCCAG AAGAAACCAT CCAATCCAAG AAGGAGGACC TCCCCAAGTC CTCAGAAGAA 
GCCATCCAGC CCAAAGAGGG TGACATCCCC AAGTCCTCAG CAAAACCCAT CCAGCCCAAG 
CTGGGCAATA TTGCCAAGAC CTCAGTGAAG CCCAGCCAGC CCAAGGAGAG TGATATCCCC 
AAGTCCCCAG AAGAAACCAT CCAGCCCAAG GAGGGTGACA TCCCCAAGTC CTCAGCAAAG 
CCCATCCAGC CCAAGCTGGG CAATATTCCC AAGGCCTCAG TGAAGCCCAG CCAGCCCAAG 
GAGGGTGACA TCTCCAAGTC CCCAGAAGAA GCCATCCAGC CCAAGGAGGG TGACCTCCCC 
AAGTCCCTAG AGGAAGCCAT CCAGCCCAAG GAGGGTGACA TCCCCAAGTC CCCAGAAGAA 
GCCATCCAGC CCAAGGAGGG TGACATCCCC AAGTCCCTAG AGGAAGCCAT CCAGCCTAAG 
GAGGGTGACA TCCCCAAGTC CCCAGAAGAA ACCATCCAGC CCAAGAAGGG TGACATCCCC 
AAGTCCCCAG AAGAAGCCAT CCAGCCCAAG GAGGGTGACA TTCCCAAGTC TCCAAAACAA 
GCCATCCAGC CCAAGGAGGG TGACATTCCC AAGTCCCTAG AGGAAGCCAT CCCACCCAAG 
GAGATTGACA TCCCCAAGTC CCCAGAAGAA ACCATCCAGC CCAAGGAGGA TGACAGCCCC 
AAGTCCCTAG AAGAAGCCAC CCCATCCAAG GAGGGTGACA TCCTAAAGCC TGAAGAAGAA 
ACAATGGAGT TCCCGGAGGG GGACAAGGTG AAAGTGATCC TGAGCAAGGA GGACTTTGAG 
GCATCACTGA AGGAGGCCGG GGAGAGGCTG GTGGCTGTGG ACTTCTCGGC CACGTGGTGT 
GGGCCCTGCA GGACCATCAG ACCATTCTTC CATGCCCTGT CTGTGAAGCA TGAGGATGTG 
GTGTTCCTGG AGGTGGACGC TGACAACTGT GAGGAGGTGG TGAGAGAGTG CGCCATCATG 
TGTGTCCCAA CCTTTCAGTT TTATAAAAAA GAAGAAAAGG TGGATGAACT TTGCGGCGCC 
CTTAAGGAAA AACTTGAAGC AGTCATTGCA GAATTAAAGT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001091999.1
CDS	203..1864
Translation	MDVDKELGMESVKAGASGKPEMRLGTQEETSEGDANESSLLVLSSNVPLLALEFLEIAQAKEKAFLPMVSHTFHMRTEESDASQEGDDLPKSSANTSHPKQDDSPKSSEETIQPKEGDIPKAPEETIQSKKEDLPKSSEKAIQPKESNIPKSSAKPIQPKLGNIPKASVKPSQPKEGDIPKAPEETIQSKKEDLPKSSEEAIQPKEGDIPKSSAKPIQPKLGNIAKTSVKPSQPKESDIPKSPEETIQPKEGDIPKSSAKPIQPKLGNIPKASVKPSQPKEGDISKSPEEAIQPKEGDLPKSLEEAIQPKEGDIPKSPEEAIQPKEGDIPKSLEEAIQPKEGDIPKSPEETIQPKKGDIPKSPEEAIQPKEGDIPKSPKQAIQPKEGDIPKSLEEAIPPKEIDIPKSPEETIQPKEDDSPKSLEEATPSKEGDILKPEEETMEFPEGDKVKVILSKEDFEASLKEAGERLVAVDFSATWCGPCRTIRPFFHALSVKHEDVVFLEVDADNCEEVVRECAIMCVPTFQFYKKEEKVDELCGALKEKLEAVIAELK

Target ORF information:

RefSeq Version	NM_001098529.2
Organism	Homo sapiens(human)
Definition	Homo sapiens thioredoxin domain containing 2 (TXNDC2), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001098529.2

ORF Insert Sequence:

ATGGATGTAG ACAAGGAACT AGGAATGGAA AGTGTTAAAG CTGGAGCCTC TGGAAAACCA 
GAAATGAGGC TGGGCACTCA GGAAGAAACA AGTGAAGGTG ATGCTAATGA AAGCTCATTA 
CTAGTCCTGT CCAGCAACGT GCCTCTCCTG GCCCTAGAGT TCTTGGAAAT AGCCCAGGCC 
AAAGAGAAGG CCTTTCTCCC CATGGTCAGC CACACGTTCC ACATGCGCAC AGAGGAGTCT 
GATGCCTCAC AGGAGGGCGA TGACCTACCC AAGTCCTCAG CAAACACCAG CCATCCCAAG 
CAGGATGACA GCCCCAAGTC CTCAGAAGAA ACCATCCAGC CCAAGGAGGG TGACATCCCC 
AAGGCCCCAG AAGAAACCAT CCAATCCAAG AAGGAGGACC TCCCCAAGTC CTCAGAAAAA 
GCCATCCAGC CCAAAGAGAG TAACATCCCC AAGTCCTCAG CAAAACCCAT CCAGCCCAAG 
CTGGGCAATA TTCCCAAGGC CTCAGTGAAG CCCAGCCAGC CCAAGGAGGG TGACATCCCC 
AAGGCCCCAG AAGAAACCAT CCAATCCAAG AAGGAGGACC TCCCCAAGTC CTCAGAAGAA 
GCCATCCAGC CCAAAGAGGG TGACATCCCC AAGTCCTCAG CAAAACCCAT CCAGCCCAAG 
CTGGGCAATA TTGCCAAGAC CTCAGTGAAG CCCAGCCAGC CCAAGGAGAG TGATATCCCC 
AAGTCCCCAG AAGAAACCAT CCAGCCCAAG GAGGGTGACA TCCCCAAGTC CTCAGCAAAG 
CCCATCCAGC CCAAGCTGGG CAATATTCCC AAGGCCTCAG TGAAGCCCAG CCAGCCCAAG 
GAGGGTGACA TCTCCAAGTC CCCAGAAGAA GCCATCCAGC CCAAGGAGGG TGACCTCCCC 
AAGTCCCTAG AGGAAGCCAT CCAGCCCAAG GAGGGTGACA TCCCCAAGTC CCCAGAAGAA 
GCCATCCAGC CCAAGGAGGG TGACATCCCC AAGTCCCTAG AGGAAGCCAT CCAGCCTAAG 
GAGGGTGACA TCCCCAAGTC CCCAGAAGAA ACCATCCAGC CCAAGAAGGG TGACATCCCC 
AAGTCCCCAG AAGAAGCCAT CCAGCCCAAG GAGGGTGACA TTCCCAAGTC TCCAAAACAA 
GCCATCCAGC CCAAGGAGGG TGACATTCCC AAGTCCCTAG AGGAAGCCAT CCCACCCAAG 
GAGATTGACA TCCCCAAGTC CCCAGAAGAA ACCATCCAGC CCAAGGAGGA TGACAGCCCC 
AAGTCCCTAG AAGAAGCCAC CCCATCCAAG GAGGGTGACA TCCTAAAGCC TGAAGAAGAA 
ACAATGGAGT TCCCGGAGGG GGACAAGGTG AAAGTGATCC TGAGCAAGGA GGACTTTGAG 
GCATCACTGA AGGAGGCCGG GGAGAGGCTG GTGGCTGTGG ACTTCTCGGC CACGTGGTGT 
GGGCCCTGCA GGACCATCAG ACCATTCTTC CATGCCCTGT CTGTGAAGCA TGAGGATGTG 
GTGTTCCTGG AGGTGGACGC TGACAACTGT GAGGAGGTGG TGAGAGAGTG CGCCATCATG 
TGTGTCCCAA CCTTTCAGTT TTATAAAAAA GAAGAAAAGG TGGATGAACT TTGCGGCGCC 
CTTAAGGAAA AACTTGAAGC AGTCATTGCA GAATTAAAGT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TXNDC2 ( NM_001098529.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001091999.1 Homo sapiens thioredoxin domain containing 2 (TXNDC2), transcript variant 2, mRNA.

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CloneID	OHu55604
Clone ID Related Accession (Same CDS sequence)	NM_001098529.2 , NM_001098529.1
Accession Version	NM_001098529.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1662bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-19
Organism	Homo sapiens(human)
Product	thioredoxin domain-containing protein 2 isoform 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DB032859.1, AK097656.1, AF080095.1 and BC050132.1. Transcript Variant: This variant (2) uses a different splice site, resulting in a longer open reading frame through the use of an upstream start codon, compared to variant 1. The predicted protein (isoform 2) has a longer N-terminus compared to isoform 1. ##Evidence-Data-START## Transcript exon combination :: HM005528.1, AK097656.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA2148093 [ECO:0000348] ##Evidence-Data-END##

ATGGATGTAG ACAAGGAACT AGGAATGGAA AGTGTTAAAG CTGGAGCCTC TGGAAAACCA 
GAAATGAGGC TGGGCACTCA GGAAGAAACA AGTGAAGGTG ATGCTAATGA AAGCTCATTA 
CTAGTCCTGT CCAGCAACGT GCCTCTCCTG GCCCTAGAGT TCTTGGAAAT AGCCCAGGCC 
AAAGAGAAGG CCTTTCTCCC CATGGTCAGC CACACGTTCC ACATGCGCAC AGAGGAGTCT 
GATGCCTCAC AGGAGGGCGA TGACCTACCC AAGTCCTCAG CAAACACCAG CCATCCCAAG 
CAGGATGACA GCCCCAAGTC CTCAGAAGAA ACCATCCAGC CCAAGGAGGG TGACATCCCC 
AAGGCCCCAG AAGAAACCAT CCAATCCAAG AAGGAGGACC TCCCCAAGTC CTCAGAAAAA 
GCCATCCAGC CCAAAGAGAG TAACATCCCC AAGTCCTCAG CAAAACCCAT CCAGCCCAAG 
CTGGGCAATA TTCCCAAGGC CTCAGTGAAG CCCAGCCAGC CCAAGGAGGG TGACATCCCC 
AAGGCCCCAG AAGAAACCAT CCAATCCAAG AAGGAGGACC TCCCCAAGTC CTCAGAAGAA 
GCCATCCAGC CCAAAGAGGG TGACATCCCC AAGTCCTCAG CAAAACCCAT CCAGCCCAAG 
CTGGGCAATA TTGCCAAGAC CTCAGTGAAG CCCAGCCAGC CCAAGGAGAG TGATATCCCC 
AAGTCCCCAG AAGAAACCAT CCAGCCCAAG GAGGGTGACA TCCCCAAGTC CTCAGCAAAG 
CCCATCCAGC CCAAGCTGGG CAATATTCCC AAGGCCTCAG TGAAGCCCAG CCAGCCCAAG 
GAGGGTGACA TCTCCAAGTC CCCAGAAGAA GCCATCCAGC CCAAGGAGGG TGACCTCCCC 
AAGTCCCTAG AGGAAGCCAT CCAGCCCAAG GAGGGTGACA TCCCCAAGTC CCCAGAAGAA 
GCCATCCAGC CCAAGGAGGG TGACATCCCC AAGTCCCTAG AGGAAGCCAT CCAGCCTAAG 
GAGGGTGACA TCCCCAAGTC CCCAGAAGAA ACCATCCAGC CCAAGAAGGG TGACATCCCC 
AAGTCCCCAG AAGAAGCCAT CCAGCCCAAG GAGGGTGACA TTCCCAAGTC TCCAAAACAA 
GCCATCCAGC CCAAGGAGGG TGACATTCCC AAGTCCCTAG AGGAAGCCAT CCCACCCAAG 
GAGATTGACA TCCCCAAGTC CCCAGAAGAA ACCATCCAGC CCAAGGAGGA TGACAGCCCC 
AAGTCCCTAG AAGAAGCCAC CCCATCCAAG GAGGGTGACA TCCTAAAGCC TGAAGAAGAA 
ACAATGGAGT TCCCGGAGGG GGACAAGGTG AAAGTGATCC TGAGCAAGGA GGACTTTGAG 
GCATCACTGA AGGAGGCCGG GGAGAGGCTG GTGGCTGTGG ACTTCTCGGC CACGTGGTGT 
GGGCCCTGCA GGACCATCAG ACCATTCTTC CATGCCCTGT CTGTGAAGCA TGAGGATGTG 
GTGTTCCTGG AGGTGGACGC TGACAACTGT GAGGAGGTGG TGAGAGAGTG CGCCATCATG 
TGTGTCCCAA CCTTTCAGTT TTATAAAAAA GAAGAAAAGG TGGATGAACT TTGCGGCGCC 
CTTAAGGAAA AACTTGAAGC AGTCATTGCA GAATTAAAGT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001091999.1
CDS	450..2111
Translation	MDVDKELGMESVKAGASGKPEMRLGTQEETSEGDANESSLLVLSSNVPLLALEFLEIAQAKEKAFLPMVSHTFHMRTEESDASQEGDDLPKSSANTSHPKQDDSPKSSEETIQPKEGDIPKAPEETIQSKKEDLPKSSEKAIQPKESNIPKSSAKPIQPKLGNIPKASVKPSQPKEGDIPKAPEETIQSKKEDLPKSSEEAIQPKEGDIPKSSAKPIQPKLGNIAKTSVKPSQPKESDIPKSPEETIQPKEGDIPKSSAKPIQPKLGNIPKASVKPSQPKEGDISKSPEEAIQPKEGDLPKSLEEAIQPKEGDIPKSPEEAIQPKEGDIPKSLEEAIQPKEGDIPKSPEETIQPKKGDIPKSPEEAIQPKEGDIPKSPKQAIQPKEGDIPKSLEEAIPPKEIDIPKSPEETIQPKEDDSPKSLEEATPSKEGDILKPEEETMEFPEGDKVKVILSKEDFEASLKEAGERLVAVDFSATWCGPCRTIRPFFHALSVKHEDVVFLEVDADNCEEVVRECAIMCVPTFQFYKKEEKVDELCGALKEKLEAVIAELK

Target ORF information:

RefSeq Version	NM_001098529.1
Organism	Homo sapiens(human)
Definition	Homo sapiens thioredoxin domain containing 2 (TXNDC2), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001098529.1

ORF Insert Sequence:

ATGGATGTAG ACAAGGAACT AGGAATGGAA AGTGTTAAAG CTGGAGCCTC TGGAAAACCA 
GAAATGAGGC TGGGCACTCA GGAAGAAACA AGTGAAGGTG ATGCTAATGA AAGCTCATTA 
CTAGTCCTGT CCAGCAACGT GCCTCTCCTG GCCCTAGAGT TCTTGGAAAT AGCCCAGGCC 
AAAGAGAAGG CCTTTCTCCC CATGGTCAGC CACACGTTCC ACATGCGCAC AGAGGAGTCT 
GATGCCTCAC AGGAGGGCGA TGACCTACCC AAGTCCTCAG CAAACACCAG CCATCCCAAG 
CAGGATGACA GCCCCAAGTC CTCAGAAGAA ACCATCCAGC CCAAGGAGGG TGACATCCCC 
AAGGCCCCAG AAGAAACCAT CCAATCCAAG AAGGAGGACC TCCCCAAGTC CTCAGAAAAA 
GCCATCCAGC CCAAAGAGAG TAACATCCCC AAGTCCTCAG CAAAACCCAT CCAGCCCAAG 
CTGGGCAATA TTCCCAAGGC CTCAGTGAAG CCCAGCCAGC CCAAGGAGGG TGACATCCCC 
AAGGCCCCAG AAGAAACCAT CCAATCCAAG AAGGAGGACC TCCCCAAGTC CTCAGAAGAA 
GCCATCCAGC CCAAAGAGGG TGACATCCCC AAGTCCTCAG CAAAACCCAT CCAGCCCAAG 
CTGGGCAATA TTGCCAAGAC CTCAGTGAAG CCCAGCCAGC CCAAGGAGAG TGATATCCCC 
AAGTCCCCAG AAGAAACCAT CCAGCCCAAG GAGGGTGACA TCCCCAAGTC CTCAGCAAAG 
CCCATCCAGC CCAAGCTGGG CAATATTCCC AAGGCCTCAG TGAAGCCCAG CCAGCCCAAG 
GAGGGTGACA TCTCCAAGTC CCCAGAAGAA GCCATCCAGC CCAAGGAGGG TGACCTCCCC 
AAGTCCCTAG AGGAAGCCAT CCAGCCCAAG GAGGGTGACA TCCCCAAGTC CCCAGAAGAA 
GCCATCCAGC CCAAGGAGGG TGACATCCCC AAGTCCCTAG AGGAAGCCAT CCAGCCTAAG 
GAGGGTGACA TCCCCAAGTC CCCAGAAGAA ACCATCCAGC CCAAGAAGGG TGACATCCCC 
AAGTCCCCAG AAGAAGCCAT CCAGCCCAAG GAGGGTGACA TTCCCAAGTC TCCAAAACAA 
GCCATCCAGC CCAAGGAGGG TGACATTCCC AAGTCCCTAG AGGAAGCCAT CCCACCCAAG 
GAGATTGACA TCCCCAAGTC CCCAGAAGAA ACCATCCAGC CCAAGGAGGA TGACAGCCCC 
AAGTCCCTAG AAGAAGCCAC CCCATCCAAG GAGGGTGACA TCCTAAAGCC TGAAGAAGAA 
ACAATGGAGT TCCCGGAGGG GGACAAGGTG AAAGTGATCC TGAGCAAGGA GGACTTTGAG 
GCATCACTGA AGGAGGCCGG GGAGAGGCTG GTGGCTGTGG ACTTCTCGGC CACGTGGTGT 
GGGCCCTGCA GGACCATCAG ACCATTCTTC CATGCCCTGT CTGTGAAGCA TGAGGATGTG 
GTGTTCCTGG AGGTGGACGC TGACAACTGT GAGGAGGTGG TGAGAGAGTG CGCCATCATG 
TGTGTCCCAA CCTTTCAGTT TTATAAAAAA GAAGAAAAGG TGGATGAACT TTGCGGCGCC 
CTTAAGGAAA AACTTGAAGC AGTCATTGCA GAATTAAAGT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TXNDC2 ( XM_017026041.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016881530.1 Homo sapiens thioredoxin domain containing 2 (TXNDC2), transcript variant X1, mRNA.

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CloneID	OHu32347
Clone ID Related Accession (Same CDS sequence)	NM_032243.5 , XM_017026041.1 , NM_032243.6
Accession Version	XM_017026041.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1461bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	thioredoxin domain-containing protein 2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000018.10) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGTCAGCC ACACGTTCCA CATGCGCACA GAGGAGTCTG ATGCCTCACA GGAGGGCGAT 
GACCTACCCA AGTCCTCAGC AAACACCAGC CATCCCAAGC AGGATGACAG CCCCAAGTCC 
TCAGAAGAAA CCATCCAGCC CAAGGAGGGT GACATCCCCA AGGCCCCAGA AGAAACCATC 
CAATCCAAGA AGGAGGACCT CCCCAAGTCC TCAGAAAAAG CCATCCAGCC CAAAGAGAGT 
AACATCCCCA AGTCCTCAGC AAAACCCATC CAGCCCAAGC TGGGCAATAT TCCCAAGGCC 
TCAGTGAAGC CCAGCCAGCC CAAGGAGGGT GACATCCCCA AGGCCCCAGA AGAAACCATC 
CAATCCAAGA AGGAGGACCT CCCCAAGTCC TCAGAAGAAG CCATCCAGCC CAAAGAGGGT 
GACATCCCCA AGTCCTCAGC AAAACCCATC CAGCCCAAGC TGGGCAATAT TGCCAAGACC 
TCAGTGAAGC CCAGCCAGCC CAAGGAGAGT GATATCCCCA AGTCCCCAGA AGAAACCATC 
CAGCCCAAGG AGGGTGACAT CCCCAAGTCC TCAGCAAAGC CCATCCAGCC CAAGCTGGGC 
AATATTCCCA AGGCCTCAGT GAAGCCCAGC CAGCCCAAGG AGGGTGACAT CTCCAAGTCC 
CCAGAAGAAG CCATCCAGCC CAAGGAGGGT GACCTCCCCA AGTCCCTAGA GGAAGCCATC 
CAGCCCAAGG AGGGTGACAT CCCCAAGTCC CCAGAAGAAG CCATCCAGCC CAAGGAGGGT 
GACATCCCCA AGTCCCTAGA GGAAGCCATC CAGCCTAAGG AGGGTGACAT CCCCAAGTCC 
CCAGAAGAAA CCATCCAGCC CAAGAAGGGT GACATCCCCA AGTCCCCAGA AGAAGCCATC 
CAGCCCAAGG AGGGTGACAT TCCCAAGTCT CCAAAACAAG CCATCCAGCC CAAGGAGGGT 
GACATTCCCA AGTCCCTAGA GGAAGCCATC CCACCCAAGG AGATTGACAT CCCCAAGTCC 
CCAGAAGAAA CCATCCAGCC CAAGGAGGAT GACAGCCCCA AGTCCCTAGA AGAAGCCACC 
CCATCCAAGG AGGGTGACAT CCTAAAGCCT GAAGAAGAAA CAATGGAGTT CCCGGAGGGG 
GACAAGGTGA AAGTGATCCT GAGCAAGGAG GACTTTGAGG CATCACTGAA GGAGGCCGGG 
GAGAGGCTGG TGGCTGTGGA CTTCTCGGCC ACGTGGTGTG GGCCCTGCAG GACCATCAGA 
CCATTCTTCC ATGCCCTGTC TGTGAAGCAT GAGGATGTGG TGTTCCTGGA GGTGGACGCT 
GACAACTGTG AGGAGGTGGT GAGAGAGTGC GCCATCATGT GTGTCCCAAC CTTTCAGTTT 
TATAAAAAAG AAGAAAAGGT GGATGAACTT TGCGGCGCCC TTAAGGAAAA ACTTGAAGCA 
GTCATTGCAG AATTAAAGTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016881530.1
CDS	322..1782
Translation	MVSHTFHMRTEESDASQEGDDLPKSSANTSHPKQDDSPKSSEETIQPKEGDIPKAPEETIQSKKEDLPKSSEKAIQPKESNIPKSSAKPIQPKLGNIPKASVKPSQPKEGDIPKAPEETIQSKKEDLPKSSEEAIQPKEGDIPKSSAKPIQPKLGNIAKTSVKPSQPKESDIPKSPEETIQPKEGDIPKSSAKPIQPKLGNIPKASVKPSQPKEGDISKSPEEAIQPKEGDLPKSLEEAIQPKEGDIPKSPEEAIQPKEGDIPKSLEEAIQPKEGDIPKSPEETIQPKKGDIPKSPEEAIQPKEGDIPKSPKQAIQPKEGDIPKSLEEAIPPKEIDIPKSPEETIQPKEDDSPKSLEEATPSKEGDILKPEEETMEFPEGDKVKVILSKEDFEASLKEAGERLVAVDFSATWCGPCRTIRPFFHALSVKHEDVVFLEVDADNCEEVVRECAIMCVPTFQFYKKEEKVDELCGALKEKLEAVIAELK

Target ORF information:

RefSeq Version	XM_017026041.1
Organism	Homo sapiens(human)
Definition	Homo sapiens thioredoxin domain containing 2 (TXNDC2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017026041.1

ORF Insert Sequence:

ATGGTCAGCC ACACGTTCCA CATGCGCACA GAGGAGTCTG ATGCCTCACA GGAGGGCGAT 
GACCTACCCA AGTCCTCAGC AAACACCAGC CATCCCAAGC AGGATGACAG CCCCAAGTCC 
TCAGAAGAAA CCATCCAGCC CAAGGAGGGT GACATCCCCA AGGCCCCAGA AGAAACCATC 
CAATCCAAGA AGGAGGACCT CCCCAAGTCC TCAGAAAAAG CCATCCAGCC CAAAGAGAGT 
AACATCCCCA AGTCCTCAGC AAAACCCATC CAGCCCAAGC TGGGCAATAT TCCCAAGGCC 
TCAGTGAAGC CCAGCCAGCC CAAGGAGGGT GACATCCCCA AGGCCCCAGA AGAAACCATC 
CAATCCAAGA AGGAGGACCT CCCCAAGTCC TCAGAAGAAG CCATCCAGCC CAAAGAGGGT 
GACATCCCCA AGTCCTCAGC AAAACCCATC CAGCCCAAGC TGGGCAATAT TGCCAAGACC 
TCAGTGAAGC CCAGCCAGCC CAAGGAGAGT GATATCCCCA AGTCCCCAGA AGAAACCATC 
CAGCCCAAGG AGGGTGACAT CCCCAAGTCC TCAGCAAAGC CCATCCAGCC CAAGCTGGGC 
AATATTCCCA AGGCCTCAGT GAAGCCCAGC CAGCCCAAGG AGGGTGACAT CTCCAAGTCC 
CCAGAAGAAG CCATCCAGCC CAAGGAGGGT GACCTCCCCA AGTCCCTAGA GGAAGCCATC 
CAGCCCAAGG AGGGTGACAT CCCCAAGTCC CCAGAAGAAG CCATCCAGCC CAAGGAGGGT 
GACATCCCCA AGTCCCTAGA GGAAGCCATC CAGCCTAAGG AGGGTGACAT CCCCAAGTCC 
CCAGAAGAAA CCATCCAGCC CAAGAAGGGT GACATCCCCA AGTCCCCAGA AGAAGCCATC 
CAGCCCAAGG AGGGTGACAT TCCCAAGTCT CCAAAACAAG CCATCCAGCC CAAGGAGGGT 
GACATTCCCA AGTCCCTAGA GGAAGCCATC CCACCCAAGG AGATTGACAT CCCCAAGTCC 
CCAGAAGAAA CCATCCAGCC CAAGGAGGAT GACAGCCCCA AGTCCCTAGA AGAAGCCACC 
CCATCCAAGG AGGGTGACAT CCTAAAGCCT GAAGAAGAAA CAATGGAGTT CCCGGAGGGG 
GACAAGGTGA AAGTGATCCT GAGCAAGGAG GACTTTGAGG CATCACTGAA GGAGGCCGGG 
GAGAGGCTGG TGGCTGTGGA CTTCTCGGCC ACGTGGTGTG GGCCCTGCAG GACCATCAGA 
CCATTCTTCC ATGCCCTGTC TGTGAAGCAT GAGGATGTGG TGTTCCTGGA GGTGGACGCT 
GACAACTGTG AGGAGGTGGT GAGAGAGTGC GCCATCATGT GTGTCCCAAC CTTTCAGTTT 
TATAAAAAAG AAGAAAAGGT GGATGAACTT TGCGGCGCCC TTAAGGAAAA ACTTGAAGCA 
GTCATTGCAG AATTAAAGTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Genome-wide joint meta-analysis of SNP and SNP-by-smoking interaction identifies novel loci for pulmonary function.
PLoS genetics8(12)e1003098(2012)
Hancock DB,Soler Artigas M,Gharib SA,Henry A,Manichaikul A,Ramasamy A,Loth DW,Imboden M,Koch B,McArdle WL,Smith AV,Smolonska J,Sood A,Tang W,Wilk JB,Zhai G,Zhao JH,Aschard H,Burkart KM,Curjuric I,Eijgelsheim M,Elliott P,Gu X,Harris TB,Janson C,Homuth G,Hysi PG,Liu JZ,Loehr LR,Lohman K,Loos RJ,Manning AK,Marciante KD,Obeidat M,Postma DS,Aldrich MC,Brusselle GG,Chen TH,Eiriksdottir G,Franceschini N,Heinrich J,Rotter JI,Wijmenga C,Williams OD,Bentley AR,Hofman A,Laurie CC,Lumley T,Morrison AC,Joubert BR,Rivadeneira F,Couper DJ,Kritchevsky SB,Liu Y,Wjst M,Wain LV,Vonk JM,Uitterlinden AG,Rochat T,Rich SS,Psaty BM,O'Connor GT,North KE,Mirel DB,Meibohm B,Launer LJ,Khaw KT,Hartikainen AL,Hammond CJ,Gl?ser S,Marchini J,Kraft P,Wareham NJ,V?lzke H,Stricker BH,Spector TD,Probst-Hensch NM,Jarvis D,Jarvelin MR,Heckbert SR,Gudnason V,Boezen HM,Barr RG,Cassano PA,Strachan DP,Fornage M,Hall IP,Dupuis J,Tobin MD,London SJ

Is serum thioredoxin-1 a useful clinical marker for malignant pleural mesothelioma?
Antioxidants & redox signaling15(3)685-9(2011 Aug)
Maeda R,Tabata C,Tabata R,Eguchi R,Fujimori Y,Nakano T

Human spermatid-specific thioredoxin-1 (Sptrx-1) is a two-domain protein with oxidizing activity.
FEBS letters530(1-3)79-84(2002 Oct)
Jim?nez A,Johansson C,Ljung J,Sagemark J,Berndt KD,Ren B,Tibbelin G,Ladenstein R,Kieselbach T,Holmgren A,Gustafsson JA,Miranda-Vizuete A

Sptrx-2, a fusion protein composed of one thioredoxin and three tandemly repeated NDP-kinase domains is expressed in human testis germ cells.
Genes to cells : devoted to molecular & cellular mechanisms6(12)1077-90(2001 Dec)
Sadek CM,Damdimopoulos AE,Pelto-Huikko M,Gustafsson JA,Spyrou G,Miranda-Vizuete A

Characterization of Sptrx, a novel member of the thioredoxin family specifically expressed in human spermatozoa.
The Journal of biological chemistry276(34)31567-74(2001 Aug)
Miranda-Vizuete A,Ljung J,Damdimopoulos AE,Gustafsson JA,Oko R,Pelto-Huikko M,Spyrou G

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TXNDC2 cDNA ORF clone, Homo sapiens(human)

Gene

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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