WDR75 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	WDR75
Entrez Gene ID	84128
Full Name	WD repeat domain 75
Synonyms	NET16,UTP17
General protein information	Preferred Names WD repeat domain 75 Names WD repeat-containing protein 75 U3 small nucleolar RNA-associated protein 17 homolog UTP17, small subunit (SSU) processome component, homolog
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 2 Map Location: 2q32.2

mRNA and Protein(s)

mRNA	Protein	Name
NM_032168.2	NP_115544.1	WD repeat-containing protein 75 isoform 1
NM_032168.3	NP_115544.1	WD repeat-containing protein 75 isoform 1
XM_024453168.1	XP_024308936.1	WD repeat-containing protein 75 isoform X1
NM_001303096.1	NP_001290025.1	WD repeat-containing protein 75 isoform 2

Pathways from BioSystems

Homologies

Homo sapiens (human)	WDR75	NP_115544.1
Bos taurus (cattle)	WDR75	NP_001095532.1
Pan troglodytes (chimpanzee)	WDR75	XP_001164827.1
	WDR75	XP_001106363.1
Mus musculus (house mouse)	Wdr75	NP_082875.1
Gallus gallus (chicken)	WDR75	XP_001233408.2
Drosophila melanogaster (fruit fly)	CG12050	NP_610086.3
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP007948	XP_317524.4
Canis lupus familiaris (dog)	WDR75	XP_545565.2
Rattus norvegicus (Norway rat)	Wdr75	NP_001041354.1
Danio rerio (zebrafish)	wdr75	NP_956384.1
Oryza sativa (rice)	Os12g0609800	NP_001067245.1
Xenopus tropicalis (tropical clawed frog)	wdr75	NP_001039253.1

Gene Ontology
Bibliography

Related articles in PubMed

Novel loci affecting iron homeostasis and their effects in individuals at risk for hemochromatosis.
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Nature communications54926(2014 Oct)

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Ivatt RM, Sanchez-Martinez A, Godena VK, Brown S, Ziviani E, Whitworth AJ
Proceedings of the National Academy of Sciences of the United States of America111(23)8494-9(2014 Jun)

Insights into RNA biology from an atlas of mammalian mRNA-binding proteins.
Castello A, Fischer B, Eichelbaum K, Horos R, Beckmann BM, Strein C, Davey NE, Humphreys DT, Preiss T, Steinmetz LM, Krijgsveld J, Hentze MW
Cell149(6)1393-406(2012 Jun)

The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.
Baltz AG, Munschauer M, Schwanh?usser B, Vasile A, Murakawa Y, Schueler M, Youngs N, Penfold-Brown D, Drew K, Milek M, Wyler E, Bonneau R, Selbach M, Dieterich C, Landthaler M
Molecular cell46(5)674-90(2012 Jun)

Recruitment of factors linking transcription and processing of pre-rRNA to NOR chromatin is UBF-dependent and occurs independent of transcription in human cells.
Prieto JL, McStay B
Genes & development21(16)2041-54(2007 Aug)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following WDR75 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the WDR75 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu73348	NM_032168.3 Latest version!	Homo sapiens WD repeat domain 75 (WDR75), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
OHu73347	NM_001303096.1 Latest version!	Homo sapiens WD repeat domain 75 (WDR75), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$391.30 $559.00
OHu104983	XM_024453168.1 Latest version!	Homo sapiens WD repeat domain 75 (WDR75), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00
View Old Accession Versions >>
OHu73348	NM_032168.2	Homo sapiens WD repeat domain 75 (WDR75), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
Hide Old Accession Versions >>

ORF Online Only Promotion

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

WDR75 ( NM_032168.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_115544.1 Homo sapiens WD repeat domain 75 (WDR75), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu73348
Clone ID Related Accession (Same CDS sequence)	NM_032168.2 , NM_032168.3
Accession Version	NM_032168.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2493bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-02
Organism	Homo sapiens(human)
Product	WD repeat-containing protein 75 isoform 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BC040567.1, AK023276.1 and BU619995.1. On Dec 17, 2014 this sequence version replaced NM_032168.1. Transcript Variant: This variant (1) encodes the longer isoform (1). ##Evidence-Data-START## Transcript exon combination :: BC040567.1, SRR1803611.121453.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGTGGAGG AGGAGAACAT CCGCGTGGTT CGTTGTGGCG GCAGCGAGTT GAACTTTAGG 
AGAGCTGTGT TCTCTGCAGA TTCTAAGTAT ATCTTCTGTG TCTCTGGAGA CTTTGTTAAA 
GTTTACAGCA CAGTTACAGA AGAGTGTGTA CACATACTGC ATGGACACAG AAATCTGGTG 
ACTGGAATCC AGCTTAACCC CAACAACCAT CTACAGCTGT ATTCTTGTTC CCTTGATGGC 
ACAATTAAAC TGTGGGACTA TATAGATGGC ATCTTAATAA AGACTTTCAT AGTTGGATGT 
AAACTTCATG CCCTCTTTAC TCTTGCCCAA GCTGAGGATT CTGTCTTTGT TATAGTGAAT 
AAAGAAAAAC CAGATATATT TCAGCTGGTT TCAGTGAAAC TGCCAAAATC CTCAAGCCAG 
GAAGTAGAAG CCAAGGAGCT GTCCTTTGTT TTGGATTACA TAAACCAGTC ACCCAAGTGC 
ATTGCCTTTG GAAACGAGGG AGTATATGTT GCTGCAGTAC GGGAATTTTA CTTGTCTGTT 
TATTTTTTCA AAAAGAAAAC AACATCAAGG TTTACTTTAT CATCATCAAG AAATAAGAAG 
CATGCTAAAA ACAATTTTAC ATGTGTAGCA TGTCACCCAA CGGAAGACTG CATCGCATCT 
GGTCACATGG ATGGCAAAAT TCGTCTTTGG AGGAATTTTT ATGATGATAA GAAATATACG 
TACACATGTT TACATTGGCA CCATGATATG GTTATGGATT TGGCTTTTTC AGTGACAGGC 
ACCAGTCTGC TGAGTGGCGG TCGTGAATCT GTACTTGTAG AGTGGCGCGA TGCAACAGAG 
AAGAATAAGG AGTTTCTCCC GCGTTTAGGA GCTACTATTG AACATATCTC AGTCTCGCCT 
GCAGGAGATT TATTCTGCAC TTCTCACTCT GATAATAAGA TAATAATTAT TCACCGAAAC 
CTTGAAGCAT CCGCAGTAAT TCAAGGCCTA GTGAAAGATA GGAGTATCTT CACTGGTTTG 
ATGATTGATC CAAGAACTAA AGCTTTGGTT TTGAATGGAA AACCTGGCCA CCTGCAGTTT 
TATTCTCTCC AGAGTGATAA ACAGTTATAC AATTTAGATA TTATACAGCA AGAATATATT 
AATGATTATG GTCTGATCCA AATTGAACTA ACAAAGGCTG CATTTGGCTG CTTTGGTAAC 
TGGCTTGCAA CAGTGGAACA GCGGCAAGAA AAGGAAACTG AGCTTGAATT GCAAATGAAA 
CTGTGGATGT ATAATAAGAA AACACAAGGG TTTATTCTTA ACACTAAAAT TAACATGCCA 
CACGAAGACT GCATTACAGC TCTCTGTTTC TGTAATGCAG AAAAATCTGA ACAGCCCACC 
TTGGTTACAG CTAGCAAAGA TGGTTACTTC AAAGTATGGA TATTAACAGA TGACTCTGAC 
ATATACAAAA AAGCTGTTGG CTGGACCTGT GACTTTGTTG GTAGTTATCA CAAGTATCAA 
GCAACTAACT GTTGTTTCTC CGAAGATGGT TCTTTACTAG CAGTTAGTTT TGAGGAAATA 
GTCACAATAT GGGATTCTGT AACATGGGAA CTTAAATGTA CATTTTGCCA ACGAGCTGGG 
AAAATAAGGC ACCTTTGCTT TGGGAGATTG ACGTGTTCAA AGTATCTACT TGGTGCTACT 
GAAAATGGCA TTCTTTGCTG TTGGAATCTG CTGAGCTGTG CATTGGAGTG GAATGCAAAA 
TTAAATGTTA GAGTTATGGA ACCCGATCCT AATTCAGAGA ATATTGCTGC AATCTCTCAG 
TCTTCAGTGG GTTCAGACTT GTTTGTATTT AAACCTAGTG AGCCAAGGCC ATTGTATATT 
CAAAAGGGTA TCTCCAGAGA GAAAGTCCAG TGGGGAGTGT TTGTTCCACG AGATGTCCCT 
GAATCCTTCA CCTCAGAAGC TTACCAGTGG CTAAATAGAT CCCAGTTTTA CTTCCTAACA 
AAATCACAGA GTTTATTGAC ATTCAGTACA AAGTCTCCAG AAGAAAAACT CACACCAACA 
AGCAAACAGC TGCTAGCAGA AGAAAGTCTT CCCACAACCC CATTTTATTT CATATTGGGA 
AAACACAGGC AACAGCAGGA TGAAAAACTA AACGAAACTT TAGAGAATGA GCTGGTACAA 
CTACCCTTAA CAGAAAACAT ACCCGCAATT AGTGAGCTTC TTCACACTCC AGCCCATGTC 
CTGCCATCTG CTGCTTTCCT GTGCTCCATG TTTGTAAATT CATTGCTGCT GTCTAAAGAG 
ACTAAGAGTG CTAAGGAAAT TCCTGAAGAT GTAGATATGG AAGAAGAAAA AGAAAGTGAA 
GATTCAGATG AAGAAAATGA TTTTACCGAA AAAGTCCAGG ATACAAGTAA CACAGGTTTA 
GGAGAAGACA TTATACATCA GTTGTCAAAA TCTGAAGAAA AAGAACTGAG AAAATTTAGG 
AAAATAGACT ACAGCTGGAT AGCTGCCCTT TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_115544.1
CDS	61..2553
Translation	MVEEENIRVVRCGGSELNFRRAVFSADSKYIFCVSGDFVKVYSTVTEECVHILHGHRNLVTGIQLNPNNHLQLYSCSLDGTIKLWDYIDGILIKTFIVGCKLHALFTLAQAEDSVFVIVNKEKPDIFQLVSVKLPKSSSQEVEAKELSFVLDYINQSPKCIAFGNEGVYVAAVREFYLSVYFFKKKTTSRFTLSSSRNKKHAKNNFTCVACHPTEDCIASGHMDGKIRLWRNFYDDKKYTYTCLHWHHDMVMDLAFSVTGTSLLSGGRESVLVEWRDATEKNKEFLPRLGATIEHISVSPAGDLFCTSHSDNKIIIIHRNLEASAVIQGLVKDRSIFTGLMIDPRTKALVLNGKPGHLQFYSLQSDKQLYNLDIIQQEYINDYGLIQIELTKAAFGCFGNWLATVEQRQEKETELELQMKLWMYNKKTQGFILNTKINMPHEDCITALCFCNAEKSEQPTLVTASKDGYFKVWILTDDSDIYKKAVGWTCDFVGSYHKYQATNCCFSEDGSLLAVSFEEIVTIWDSVTWELKCTFCQRAGKIRHLCFGRLTCSKYLLGATENGILCCWNLLSCALEWNAKLNVRVMEPDPNSENIAAISQSSVGSDLFVFKPSEPRPLYIQKGISREKVQWGVFVPRDVPESFTSEAYQWLNRSQFYFLTKSQSLLTFSTKSPEEKLTPTSKQLLAEESLPTTPFYFILGKHRQQQDEKLNETLENELVQLPLTENIPAISELLHTPAHVLPSAAFLCSMFVNSLLLSKETKSAKEIPEDVDMEEEKESEDSDEENDFTEKVQDTSNTGLGEDIIHQLSKSEEKELRKFRKIDYSWIAAL

Target ORF information:

RefSeq Version	NM_032168.2
Organism	Homo sapiens(human)
Definition	Homo sapiens WD repeat domain 75 (WDR75), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_032168.2

ORF Insert Sequence:

ATGGTGGAGG AGGAGAACAT CCGCGTGGTT CGTTGTGGCG GCAGCGAGTT GAACTTTAGG 
AGAGCTGTGT TCTCTGCAGA TTCTAAGTAT ATCTTCTGTG TCTCTGGAGA CTTTGTTAAA 
GTTTACAGCA CAGTTACAGA AGAGTGTGTA CACATACTGC ATGGACACAG AAATCTGGTG 
ACTGGAATCC AGCTTAACCC CAACAACCAT CTACAGCTGT ATTCTTGTTC CCTTGATGGC 
ACAATTAAAC TGTGGGACTA TATAGATGGC ATCTTAATAA AGACTTTCAT AGTTGGATGT 
AAACTTCATG CCCTCTTTAC TCTTGCCCAA GCTGAGGATT CTGTCTTTGT TATAGTGAAT 
AAAGAAAAAC CAGATATATT TCAGCTGGTT TCAGTGAAAC TGCCAAAATC CTCAAGCCAG 
GAAGTAGAAG CCAAGGAGCT GTCCTTTGTT TTGGATTACA TAAACCAGTC ACCCAAGTGC 
ATTGCCTTTG GAAACGAGGG AGTATATGTT GCTGCAGTAC GGGAATTTTA CTTGTCTGTT 
TATTTTTTCA AAAAGAAAAC AACATCAAGG TTTACTTTAT CATCATCAAG AAATAAGAAG 
CATGCTAAAA ACAATTTTAC ATGTGTAGCA TGTCACCCAA CGGAAGACTG CATCGCATCT 
GGTCACATGG ATGGCAAAAT TCGTCTTTGG AGGAATTTTT ATGATGATAA GAAATATACG 
TACACATGTT TACATTGGCA CCATGATATG GTTATGGATT TGGCTTTTTC AGTGACAGGC 
ACCAGTCTGC TGAGTGGCGG TCGTGAATCT GTACTTGTAG AGTGGCGCGA TGCAACAGAG 
AAGAATAAGG AGTTTCTCCC GCGTTTAGGA GCTACTATTG AACATATCTC AGTCTCGCCT 
GCAGGAGATT TATTCTGCAC TTCTCACTCT GATAATAAGA TAATAATTAT TCACCGAAAC 
CTTGAAGCAT CCGCAGTAAT TCAAGGCCTA GTGAAAGATA GGAGTATCTT CACTGGTTTG 
ATGATTGATC CAAGAACTAA AGCTTTGGTT TTGAATGGAA AACCTGGCCA CCTGCAGTTT 
TATTCTCTCC AGAGTGATAA ACAGTTATAC AATTTAGATA TTATACAGCA AGAATATATT 
AATGATTATG GTCTGATCCA AATTGAACTA ACAAAGGCTG CATTTGGCTG CTTTGGTAAC 
TGGCTTGCAA CAGTGGAACA GCGGCAAGAA AAGGAAACTG AGCTTGAATT GCAAATGAAA 
CTGTGGATGT ATAATAAGAA AACACAAGGG TTTATTCTTA ACACTAAAAT TAACATGCCA 
CACGAAGACT GCATTACAGC TCTCTGTTTC TGTAATGCAG AAAAATCTGA ACAGCCCACC 
TTGGTTACAG CTAGCAAAGA TGGTTACTTC AAAGTATGGA TATTAACAGA TGACTCTGAC 
ATATACAAAA AAGCTGTTGG CTGGACCTGT GACTTTGTTG GTAGTTATCA CAAGTATCAA 
GCAACTAACT GTTGTTTCTC CGAAGATGGT TCTTTACTAG CAGTTAGTTT TGAGGAAATA 
GTCACAATAT GGGATTCTGT AACATGGGAA CTTAAATGTA CATTTTGCCA ACGAGCTGGG 
AAAATAAGGC ACCTTTGCTT TGGGAGATTG ACGTGTTCAA AGTATCTACT TGGTGCTACT 
GAAAATGGCA TTCTTTGCTG TTGGAATCTG CTGAGCTGTG CATTGGAGTG GAATGCAAAA 
TTAAATGTTA GAGTTATGGA ACCCGATCCT AATTCAGAGA ATATTGCTGC AATCTCTCAG 
TCTTCAGTGG GTTCAGACTT GTTTGTATTT AAACCTAGTG AGCCAAGGCC ATTGTATATT 
CAAAAGGGTA TCTCCAGAGA GAAAGTCCAG TGGGGAGTGT TTGTTCCACG AGATGTCCCT 
GAATCCTTCA CCTCAGAAGC TTACCAGTGG CTAAATAGAT CCCAGTTTTA CTTCCTAACA 
AAATCACAGA GTTTATTGAC ATTCAGTACA AAGTCTCCAG AAGAAAAACT CACACCAACA 
AGCAAACAGC TGCTAGCAGA AGAAAGTCTT CCCACAACCC CATTTTATTT CATATTGGGA 
AAACACAGGC AACAGCAGGA TGAAAAACTA AACGAAACTT TAGAGAATGA GCTGGTACAA 
CTACCCTTAA CAGAAAACAT ACCCGCAATT AGTGAGCTTC TTCACACTCC AGCCCATGTC 
CTGCCATCTG CTGCTTTCCT GTGCTCCATG TTTGTAAATT CATTGCTGCT GTCTAAAGAG 
ACTAAGAGTG CTAAGGAAAT TCCTGAAGAT GTAGATATGG AAGAAGAAAA AGAAAGTGAA 
GATTCAGATG AAGAAAATGA TTTTACCGAA AAAGTCCAGG ATACAAGTAA CACAGGTTTA 
GGAGAAGACA TTATACATCA GTTGTCAAAA TCTGAAGAAA AAGAACTGAG AAAATTTAGG 
AAAATAGACT ACAGCTGGAT AGCTGCCCTT TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

WDR75 ( NM_032168.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_115544.1 Homo sapiens WD repeat domain 75 (WDR75), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu73348
Clone ID Related Accession (Same CDS sequence)	NM_032168.2 , NM_032168.3
Accession Version	NM_032168.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2493bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-05-01
Organism	Homo sapiens(human)
Product	WD repeat-containing protein 75 isoform 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BC040567.1, AK023276.1 and BU619995.1. On Nov 22, 2018 this sequence version replaced NM_032168.2. Transcript Variant: This variant (1) encodes the longer isoform (1). ##Evidence-Data-START## Transcript exon combination :: SRR1803617.13618.1, SRR1660805.104256.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000314761.9/ ENSP00000314193.4 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGTGGAGG AGGAGAACAT CCGCGTGGTT CGTTGTGGCG GCAGCGAGTT GAACTTTAGG 
AGAGCTGTGT TCTCTGCAGA TTCTAAGTAT ATCTTCTGTG TCTCTGGAGA CTTTGTTAAA 
GTTTACAGCA CAGTTACAGA AGAGTGTGTA CACATACTGC ATGGACACAG AAATCTGGTG 
ACTGGAATCC AGCTTAACCC CAACAACCAT CTACAGCTGT ATTCTTGTTC CCTTGATGGC 
ACAATTAAAC TGTGGGACTA TATAGATGGC ATCTTAATAA AGACTTTCAT AGTTGGATGT 
AAACTTCATG CCCTCTTTAC TCTTGCCCAA GCTGAGGATT CTGTCTTTGT TATAGTGAAT 
AAAGAAAAAC CAGATATATT TCAGCTGGTT TCAGTGAAAC TGCCAAAATC CTCAAGCCAG 
GAAGTAGAAG CCAAGGAGCT GTCCTTTGTT TTGGATTACA TAAACCAGTC ACCCAAGTGC 
ATTGCCTTTG GAAACGAGGG AGTATATGTT GCTGCAGTAC GGGAATTTTA CTTGTCTGTT 
TATTTTTTCA AAAAGAAAAC AACATCAAGG TTTACTTTAT CATCATCAAG AAATAAGAAG 
CATGCTAAAA ACAATTTTAC ATGTGTAGCA TGTCACCCAA CGGAAGACTG CATCGCATCT 
GGTCACATGG ATGGCAAAAT TCGTCTTTGG AGGAATTTTT ATGATGATAA GAAATATACG 
TACACATGTT TACATTGGCA CCATGATATG GTTATGGATT TGGCTTTTTC AGTGACAGGC 
ACCAGTCTGC TGAGTGGCGG TCGTGAATCT GTACTTGTAG AGTGGCGCGA TGCAACAGAG 
AAGAATAAGG AGTTTCTCCC GCGTTTAGGA GCTACTATTG AACATATCTC AGTCTCGCCT 
GCAGGAGATT TATTCTGCAC TTCTCACTCT GATAATAAGA TAATAATTAT TCACCGAAAC 
CTTGAAGCAT CCGCAGTAAT TCAAGGCCTA GTGAAAGATA GGAGTATCTT CACTGGTTTG 
ATGATTGATC CAAGAACTAA AGCTTTGGTT TTGAATGGAA AACCTGGCCA CCTGCAGTTT 
TATTCTCTCC AGAGTGATAA ACAGTTATAC AATTTAGATA TTATACAGCA AGAATATATT 
AATGATTATG GTCTGATCCA AATTGAACTA ACAAAGGCTG CATTTGGCTG CTTTGGTAAC 
TGGCTTGCAA CAGTGGAACA GCGGCAAGAA AAGGAAACTG AGCTTGAATT GCAAATGAAA 
CTGTGGATGT ATAATAAGAA AACACAAGGG TTTATTCTTA ACACTAAAAT TAACATGCCA 
CACGAAGACT GCATTACAGC TCTCTGTTTC TGTAATGCAG AAAAATCTGA ACAGCCCACC 
TTGGTTACAG CTAGCAAAGA TGGTTACTTC AAAGTATGGA TATTAACAGA TGACTCTGAC 
ATATACAAAA AAGCTGTTGG CTGGACCTGT GACTTTGTTG GTAGTTATCA CAAGTATCAA 
GCAACTAACT GTTGTTTCTC CGAAGATGGT TCTTTACTAG CAGTTAGTTT TGAGGAAATA 
GTCACAATAT GGGATTCTGT AACATGGGAA CTTAAATGTA CATTTTGCCA ACGAGCTGGG 
AAAATAAGGC ACCTTTGCTT TGGGAGATTG ACGTGTTCAA AGTATCTACT TGGTGCTACT 
GAAAATGGCA TTCTTTGCTG TTGGAATCTG CTGAGCTGTG CATTGGAGTG GAATGCAAAA 
TTAAATGTTA GAGTTATGGA ACCCGATCCT AATTCAGAGA ATATTGCTGC AATCTCTCAG 
TCTTCAGTGG GTTCAGACTT GTTTGTATTT AAACCTAGTG AGCCAAGGCC ATTGTATATT 
CAAAAGGGTA TCTCCAGAGA GAAAGTCCAG TGGGGAGTGT TTGTTCCACG AGATGTCCCT 
GAATCCTTCA CCTCAGAAGC TTACCAGTGG CTAAATAGAT CCCAGTTTTA CTTCCTAACA 
AAATCACAGA GTTTATTGAC ATTCAGTACA AAGTCTCCAG AAGAAAAACT CACACCAACA 
AGCAAACAGC TGCTAGCAGA AGAAAGTCTT CCCACAACCC CATTTTATTT CATATTGGGA 
AAACACAGGC AACAGCAGGA TGAAAAACTA AACGAAACTT TAGAGAATGA GCTGGTACAA 
CTACCCTTAA CAGAAAACAT ACCCGCAATT AGTGAGCTTC TTCACACTCC AGCCCATGTC 
CTGCCATCTG CTGCTTTCCT GTGCTCCATG TTTGTAAATT CATTGCTGCT GTCTAAAGAG 
ACTAAGAGTG CTAAGGAAAT TCCTGAAGAT GTAGATATGG AAGAAGAAAA AGAAAGTGAA 
GATTCAGATG AAGAAAATGA TTTTACCGAA AAAGTCCAGG ATACAAGTAA CACAGGTTTA 
GGAGAAGACA TTATACATCA GTTGTCAAAA TCTGAAGAAA AAGAACTGAG AAAATTTAGG 
AAAATAGACT ACAGCTGGAT AGCTGCCCTT TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_115544.1
CDS	20..2512
Translation	MVEEENIRVVRCGGSELNFRRAVFSADSKYIFCVSGDFVKVYSTVTEECVHILHGHRNLVTGIQLNPNNHLQLYSCSLDGTIKLWDYIDGILIKTFIVGCKLHALFTLAQAEDSVFVIVNKEKPDIFQLVSVKLPKSSSQEVEAKELSFVLDYINQSPKCIAFGNEGVYVAAVREFYLSVYFFKKKTTSRFTLSSSRNKKHAKNNFTCVACHPTEDCIASGHMDGKIRLWRNFYDDKKYTYTCLHWHHDMVMDLAFSVTGTSLLSGGRESVLVEWRDATEKNKEFLPRLGATIEHISVSPAGDLFCTSHSDNKIIIIHRNLEASAVIQGLVKDRSIFTGLMIDPRTKALVLNGKPGHLQFYSLQSDKQLYNLDIIQQEYINDYGLIQIELTKAAFGCFGNWLATVEQRQEKETELELQMKLWMYNKKTQGFILNTKINMPHEDCITALCFCNAEKSEQPTLVTASKDGYFKVWILTDDSDIYKKAVGWTCDFVGSYHKYQATNCCFSEDGSLLAVSFEEIVTIWDSVTWELKCTFCQRAGKIRHLCFGRLTCSKYLLGATENGILCCWNLLSCALEWNAKLNVRVMEPDPNSENIAAISQSSVGSDLFVFKPSEPRPLYIQKGISREKVQWGVFVPRDVPESFTSEAYQWLNRSQFYFLTKSQSLLTFSTKSPEEKLTPTSKQLLAEESLPTTPFYFILGKHRQQQDEKLNETLENELVQLPLTENIPAISELLHTPAHVLPSAAFLCSMFVNSLLLSKETKSAKEIPEDVDMEEEKESEDSDEENDFTEKVQDTSNTGLGEDIIHQLSKSEEKELRKFRKIDYSWIAAL

Target ORF information:

RefSeq Version	NM_032168.3
Organism	Homo sapiens(human)
Definition	Homo sapiens WD repeat domain 75 (WDR75), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_032168.3

ORF Insert Sequence:

ATGGTGGAGG AGGAGAACAT CCGCGTGGTT CGTTGTGGCG GCAGCGAGTT GAACTTTAGG 
AGAGCTGTGT TCTCTGCAGA TTCTAAGTAT ATCTTCTGTG TCTCTGGAGA CTTTGTTAAA 
GTTTACAGCA CAGTTACAGA AGAGTGTGTA CACATACTGC ATGGACACAG AAATCTGGTG 
ACTGGAATCC AGCTTAACCC CAACAACCAT CTACAGCTGT ATTCTTGTTC CCTTGATGGC 
ACAATTAAAC TGTGGGACTA TATAGATGGC ATCTTAATAA AGACTTTCAT AGTTGGATGT 
AAACTTCATG CCCTCTTTAC TCTTGCCCAA GCTGAGGATT CTGTCTTTGT TATAGTGAAT 
AAAGAAAAAC CAGATATATT TCAGCTGGTT TCAGTGAAAC TGCCAAAATC CTCAAGCCAG 
GAAGTAGAAG CCAAGGAGCT GTCCTTTGTT TTGGATTACA TAAACCAGTC ACCCAAGTGC 
ATTGCCTTTG GAAACGAGGG AGTATATGTT GCTGCAGTAC GGGAATTTTA CTTGTCTGTT 
TATTTTTTCA AAAAGAAAAC AACATCAAGG TTTACTTTAT CATCATCAAG AAATAAGAAG 
CATGCTAAAA ACAATTTTAC ATGTGTAGCA TGTCACCCAA CGGAAGACTG CATCGCATCT 
GGTCACATGG ATGGCAAAAT TCGTCTTTGG AGGAATTTTT ATGATGATAA GAAATATACG 
TACACATGTT TACATTGGCA CCATGATATG GTTATGGATT TGGCTTTTTC AGTGACAGGC 
ACCAGTCTGC TGAGTGGCGG TCGTGAATCT GTACTTGTAG AGTGGCGCGA TGCAACAGAG 
AAGAATAAGG AGTTTCTCCC GCGTTTAGGA GCTACTATTG AACATATCTC AGTCTCGCCT 
GCAGGAGATT TATTCTGCAC TTCTCACTCT GATAATAAGA TAATAATTAT TCACCGAAAC 
CTTGAAGCAT CCGCAGTAAT TCAAGGCCTA GTGAAAGATA GGAGTATCTT CACTGGTTTG 
ATGATTGATC CAAGAACTAA AGCTTTGGTT TTGAATGGAA AACCTGGCCA CCTGCAGTTT 
TATTCTCTCC AGAGTGATAA ACAGTTATAC AATTTAGATA TTATACAGCA AGAATATATT 
AATGATTATG GTCTGATCCA AATTGAACTA ACAAAGGCTG CATTTGGCTG CTTTGGTAAC 
TGGCTTGCAA CAGTGGAACA GCGGCAAGAA AAGGAAACTG AGCTTGAATT GCAAATGAAA 
CTGTGGATGT ATAATAAGAA AACACAAGGG TTTATTCTTA ACACTAAAAT TAACATGCCA 
CACGAAGACT GCATTACAGC TCTCTGTTTC TGTAATGCAG AAAAATCTGA ACAGCCCACC 
TTGGTTACAG CTAGCAAAGA TGGTTACTTC AAAGTATGGA TATTAACAGA TGACTCTGAC 
ATATACAAAA AAGCTGTTGG CTGGACCTGT GACTTTGTTG GTAGTTATCA CAAGTATCAA 
GCAACTAACT GTTGTTTCTC CGAAGATGGT TCTTTACTAG CAGTTAGTTT TGAGGAAATA 
GTCACAATAT GGGATTCTGT AACATGGGAA CTTAAATGTA CATTTTGCCA ACGAGCTGGG 
AAAATAAGGC ACCTTTGCTT TGGGAGATTG ACGTGTTCAA AGTATCTACT TGGTGCTACT 
GAAAATGGCA TTCTTTGCTG TTGGAATCTG CTGAGCTGTG CATTGGAGTG GAATGCAAAA 
TTAAATGTTA GAGTTATGGA ACCCGATCCT AATTCAGAGA ATATTGCTGC AATCTCTCAG 
TCTTCAGTGG GTTCAGACTT GTTTGTATTT AAACCTAGTG AGCCAAGGCC ATTGTATATT 
CAAAAGGGTA TCTCCAGAGA GAAAGTCCAG TGGGGAGTGT TTGTTCCACG AGATGTCCCT 
GAATCCTTCA CCTCAGAAGC TTACCAGTGG CTAAATAGAT CCCAGTTTTA CTTCCTAACA 
AAATCACAGA GTTTATTGAC ATTCAGTACA AAGTCTCCAG AAGAAAAACT CACACCAACA 
AGCAAACAGC TGCTAGCAGA AGAAAGTCTT CCCACAACCC CATTTTATTT CATATTGGGA 
AAACACAGGC AACAGCAGGA TGAAAAACTA AACGAAACTT TAGAGAATGA GCTGGTACAA 
CTACCCTTAA CAGAAAACAT ACCCGCAATT AGTGAGCTTC TTCACACTCC AGCCCATGTC 
CTGCCATCTG CTGCTTTCCT GTGCTCCATG TTTGTAAATT CATTGCTGCT GTCTAAAGAG 
ACTAAGAGTG CTAAGGAAAT TCCTGAAGAT GTAGATATGG AAGAAGAAAA AGAAAGTGAA 
GATTCAGATG AAGAAAATGA TTTTACCGAA AAAGTCCAGG ATACAAGTAA CACAGGTTTA 
GGAGAAGACA TTATACATCA GTTGTCAAAA TCTGAAGAAA AAGAACTGAG AAAATTTAGG 
AAAATAGACT ACAGCTGGAT AGCTGCCCTT TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

WDR75 ( NM_001303096.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001290025.1 Homo sapiens WD repeat domain 75 (WDR75), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu73347
Clone ID Related Accession (Same CDS sequence)	NM_001303096.1
Accession Version	NM_001303096.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2301bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-06-29
Organism	Homo sapiens(human)
Product	WD repeat-containing protein 75 isoform 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BI460450.1, AK091546.1, AL122097.1 and BU619995.1. Transcript Variant: This variant (2) contains an alternate exon which results in a distinct 5' UTR and use of an alternate start codon, compared to variant 1. The encoded isoform (2) has a shorter and distinct N-terminus compared to isoform 1. ##Evidence-Data-START## Transcript exon combination :: AK091546.1, SRR1803614.154704.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2149004, SAMEA2152474 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCATTGCG AATATCCAAA AGAGCTGTAT TCTTGTTCCC TTGATGGCAC AATTAAACTG 
TGGGACTATA TAGATGGCAT CTTAATAAAG ACTTTCATAG TTGGATGTAA ACTTCATGCC 
CTCTTTACTC TTGCCCAAGC TGAGGATTCT GTCTTTGTTA TAGTGAATAA AGAAAAACCA 
GATATATTTC AGCTGGTTTC AGTGAAACTG CCAAAATCCT CAAGCCAGGA AGTAGAAGCC 
AAGGAGCTGT CCTTTGTTTT GGATTACATA AACCAGTCAC CCAAGTGCAT TGCCTTTGGA 
AACGAGGGAG TATATGTTGC TGCAGTACGG GAATTTTACT TGTCTGTTTA TTTTTTCAAA 
AAGAAAACAA CATCAAGGTT TACTTTATCA TCATCAAGAA ATAAGAAGCA TGCTAAAAAC 
AATTTTACAT GTGTAGCATG TCACCCAACG GAAGACTGCA TCGCATCTGG TCACATGGAT 
GGCAAAATTC GTCTTTGGAG GAATTTTTAT GATGATAAGA AATATACGTA CACATGTTTA 
CATTGGCACC ATGATATGGT TATGGATTTG GCTTTTTCAG TGACAGGCAC CAGTCTGCTG 
AGTGGCGGTC GTGAATCTGT ACTTGTAGAG TGGCGCGATG CAACAGAGAA GAATAAGGAG 
TTTCTCCCGC GTTTAGGAGC TACTATTGAA CATATCTCAG TCTCGCCTGC AGGAGATTTA 
TTCTGCACTT CTCACTCTGA TAATAAGATA ATAATTATTC ACCGAAACCT TGAAGCATCC 
GCAGTAATTC AAGGCCTAGT GAAAGATAGG AGTATCTTCA CTGGTTTGAT GATTGATCCA 
AGAACTAAAG CTTTGGTTTT GAATGGAAAA CCTGGCCACC TGCAGTTTTA TTCTCTCCAG 
AGTGATAAAC AGTTATACAA TTTAGATATT ATACAGCAAG AATATATTAA TGATTATGGT 
CTGATCCAAA TTGAACTAAC AAAGGCTGCA TTTGGCTGCT TTGGTAACTG GCTTGCAACA 
GTGGAACAGC GGCAAGAAAA GGAAACTGAG CTTGAATTGC AAATGAAACT GTGGATGTAT 
AATAAGAAAA CACAAGGGTT TATTCTTAAC ACTAAAATTA ACATGCCACA CGAAGACTGC 
ATTACAGCTC TCTGTTTCTG TAATGCAGAA AAATCTGAAC AGCCCACCTT GGTTACAGCT 
AGCAAAGATG GTTACTTCAA AGTATGGATA TTAACAGATG ACTCTGACAT ATACAAAAAA 
GCTGTTGGCT GGACCTGTGA CTTTGTTGGT AGTTATCACA AGTATCAAGC AACTAACTGT 
TGTTTCTCCG AAGATGGTTC TTTACTAGCA GTTAGTTTTG AGGAAATAGT CACAATATGG 
GATTCTGTAA CATGGGAACT TAAATGTACA TTTTGCCAAC GAGCTGGGAA AATAAGGCAC 
CTTTGCTTTG GGAGATTGAC GTGTTCAAAG TATCTACTTG GTGCTACTGA AAATGGCATT 
CTTTGCTGTT GGAATCTGCT GAGCTGTGCA TTGGAGTGGA ATGCAAAATT AAATGTTAGA 
GTTATGGAAC CCGATCCTAA TTCAGAGAAT ATTGCTGCAA TCTCTCAGTC TTCAGTGGGT 
TCAGACTTGT TTGTATTTAA ACCTAGTGAG CCAAGGCCAT TGTATATTCA AAAGGGTATC 
TCCAGAGAGA AAGTCCAGTG GGGAGTGTTT GTTCCACGAG ATGTCCCTGA ATCCTTCACC 
TCAGAAGCTT ACCAGTGGCT AAATAGATCC CAGTTTTACT TCCTAACAAA ATCACAGAGT 
TTATTGACAT TCAGTACAAA GTCTCCAGAA GAAAAACTCA CACCAACAAG CAAACAGCTG 
CTAGCAGAAG AAAGTCTTCC CACAACCCCA TTTTATTTCA TATTGGGAAA ACACAGGCAA 
CAGCAGGATG AAAAACTAAA CGAAACTTTA GAGAATGAGC TGGTACAACT ACCCTTAACA 
GAAAACATAC CCGCAATTAG TGAGCTTCTT CACACTCCAG CCCATGTCCT GCCATCTGCT 
GCTTTCCTGT GCTCCATGTT TGTAAATTCA TTGCTGCTGT CTAAAGAGAC TAAGAGTGCT 
AAGGAAATTC CTGAAGATGT AGATATGGAA GAAGAAAAAG AAAGTGAAGA TTCAGATGAA 
GAAAATGATT TTACCGAAAA AGTCCAGGAT ACAAGTAACA CAGGTTTAGG AGAAGACATT 
ATACATCAGT TGTCAAAATC TGAAGAAAAA GAACTGAGAA AATTTAGGAA AATAGACTAC 
AGCTGGATAG CTGCCCTTTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001290025.1
CDS	287..2587
Translation	MHCEYPKELYSCSLDGTIKLWDYIDGILIKTFIVGCKLHALFTLAQAEDSVFVIVNKEKPDIFQLVSVKLPKSSSQEVEAKELSFVLDYINQSPKCIAFGNEGVYVAAVREFYLSVYFFKKKTTSRFTLSSSRNKKHAKNNFTCVACHPTEDCIASGHMDGKIRLWRNFYDDKKYTYTCLHWHHDMVMDLAFSVTGTSLLSGGRESVLVEWRDATEKNKEFLPRLGATIEHISVSPAGDLFCTSHSDNKIIIIHRNLEASAVIQGLVKDRSIFTGLMIDPRTKALVLNGKPGHLQFYSLQSDKQLYNLDIIQQEYINDYGLIQIELTKAAFGCFGNWLATVEQRQEKETELELQMKLWMYNKKTQGFILNTKINMPHEDCITALCFCNAEKSEQPTLVTASKDGYFKVWILTDDSDIYKKAVGWTCDFVGSYHKYQATNCCFSEDGSLLAVSFEEIVTIWDSVTWELKCTFCQRAGKIRHLCFGRLTCSKYLLGATENGILCCWNLLSCALEWNAKLNVRVMEPDPNSENIAAISQSSVGSDLFVFKPSEPRPLYIQKGISREKVQWGVFVPRDVPESFTSEAYQWLNRSQFYFLTKSQSLLTFSTKSPEEKLTPTSKQLLAEESLPTTPFYFILGKHRQQQDEKLNETLENELVQLPLTENIPAISELLHTPAHVLPSAAFLCSMFVNSLLLSKETKSAKEIPEDVDMEEEKESEDSDEENDFTEKVQDTSNTGLGEDIIHQLSKSEEKELRKFRKIDYSWIAAL

Target ORF information:

RefSeq Version	NM_001303096.1
Organism	Homo sapiens(human)
Definition	Homo sapiens WD repeat domain 75 (WDR75), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001303096.1

ORF Insert Sequence:

ATGCATTGCG AATATCCAAA AGAGCTGTAT TCTTGTTCCC TTGATGGCAC AATTAAACTG 
TGGGACTATA TAGATGGCAT CTTAATAAAG ACTTTCATAG TTGGATGTAA ACTTCATGCC 
CTCTTTACTC TTGCCCAAGC TGAGGATTCT GTCTTTGTTA TAGTGAATAA AGAAAAACCA 
GATATATTTC AGCTGGTTTC AGTGAAACTG CCAAAATCCT CAAGCCAGGA AGTAGAAGCC 
AAGGAGCTGT CCTTTGTTTT GGATTACATA AACCAGTCAC CCAAGTGCAT TGCCTTTGGA 
AACGAGGGAG TATATGTTGC TGCAGTACGG GAATTTTACT TGTCTGTTTA TTTTTTCAAA 
AAGAAAACAA CATCAAGGTT TACTTTATCA TCATCAAGAA ATAAGAAGCA TGCTAAAAAC 
AATTTTACAT GTGTAGCATG TCACCCAACG GAAGACTGCA TCGCATCTGG TCACATGGAT 
GGCAAAATTC GTCTTTGGAG GAATTTTTAT GATGATAAGA AATATACGTA CACATGTTTA 
CATTGGCACC ATGATATGGT TATGGATTTG GCTTTTTCAG TGACAGGCAC CAGTCTGCTG 
AGTGGCGGTC GTGAATCTGT ACTTGTAGAG TGGCGCGATG CAACAGAGAA GAATAAGGAG 
TTTCTCCCGC GTTTAGGAGC TACTATTGAA CATATCTCAG TCTCGCCTGC AGGAGATTTA 
TTCTGCACTT CTCACTCTGA TAATAAGATA ATAATTATTC ACCGAAACCT TGAAGCATCC 
GCAGTAATTC AAGGCCTAGT GAAAGATAGG AGTATCTTCA CTGGTTTGAT GATTGATCCA 
AGAACTAAAG CTTTGGTTTT GAATGGAAAA CCTGGCCACC TGCAGTTTTA TTCTCTCCAG 
AGTGATAAAC AGTTATACAA TTTAGATATT ATACAGCAAG AATATATTAA TGATTATGGT 
CTGATCCAAA TTGAACTAAC AAAGGCTGCA TTTGGCTGCT TTGGTAACTG GCTTGCAACA 
GTGGAACAGC GGCAAGAAAA GGAAACTGAG CTTGAATTGC AAATGAAACT GTGGATGTAT 
AATAAGAAAA CACAAGGGTT TATTCTTAAC ACTAAAATTA ACATGCCACA CGAAGACTGC 
ATTACAGCTC TCTGTTTCTG TAATGCAGAA AAATCTGAAC AGCCCACCTT GGTTACAGCT 
AGCAAAGATG GTTACTTCAA AGTATGGATA TTAACAGATG ACTCTGACAT ATACAAAAAA 
GCTGTTGGCT GGACCTGTGA CTTTGTTGGT AGTTATCACA AGTATCAAGC AACTAACTGT 
TGTTTCTCCG AAGATGGTTC TTTACTAGCA GTTAGTTTTG AGGAAATAGT CACAATATGG 
GATTCTGTAA CATGGGAACT TAAATGTACA TTTTGCCAAC GAGCTGGGAA AATAAGGCAC 
CTTTGCTTTG GGAGATTGAC GTGTTCAAAG TATCTACTTG GTGCTACTGA AAATGGCATT 
CTTTGCTGTT GGAATCTGCT GAGCTGTGCA TTGGAGTGGA ATGCAAAATT AAATGTTAGA 
GTTATGGAAC CCGATCCTAA TTCAGAGAAT ATTGCTGCAA TCTCTCAGTC TTCAGTGGGT 
TCAGACTTGT TTGTATTTAA ACCTAGTGAG CCAAGGCCAT TGTATATTCA AAAGGGTATC 
TCCAGAGAGA AAGTCCAGTG GGGAGTGTTT GTTCCACGAG ATGTCCCTGA ATCCTTCACC 
TCAGAAGCTT ACCAGTGGCT AAATAGATCC CAGTTTTACT TCCTAACAAA ATCACAGAGT 
TTATTGACAT TCAGTACAAA GTCTCCAGAA GAAAAACTCA CACCAACAAG CAAACAGCTG 
CTAGCAGAAG AAAGTCTTCC CACAACCCCA TTTTATTTCA TATTGGGAAA ACACAGGCAA 
CAGCAGGATG AAAAACTAAA CGAAACTTTA GAGAATGAGC TGGTACAACT ACCCTTAACA 
GAAAACATAC CCGCAATTAG TGAGCTTCTT CACACTCCAG CCCATGTCCT GCCATCTGCT 
GCTTTCCTGT GCTCCATGTT TGTAAATTCA TTGCTGCTGT CTAAAGAGAC TAAGAGTGCT 
AAGGAAATTC CTGAAGATGT AGATATGGAA GAAGAAAAAG AAAGTGAAGA TTCAGATGAA 
GAAAATGATT TTACCGAAAA AGTCCAGGAT ACAAGTAACA CAGGTTTAGG AGAAGACATT 
ATACATCAGT TGTCAAAATC TGAAGAAAAA GAACTGAGAA AATTTAGGAA AATAGACTAC 
AGCTGGATAG CTGCCCTTTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

WDR75 ( XM_024453168.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_024308936.1 Homo sapiens WD repeat domain 75 (WDR75), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu104983
Clone ID Related Accession (Same CDS sequence)	XM_024453168.1
Accession Version	XM_024453168.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1827bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	WD repeat-containing protein 75 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000002.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGATGGCA AAATTCGTCT TTGGAGGAAT TTTTATGATG ATAAGAAATA TACGTACACA 
TGTTTACATT GGCACCATGA TATGGTTATG GATTTGGCTT TTTCAGTGAC AGGCACCAGT 
CTGCTGAGTG GCGGTCGTGA ATCTGTACTT GTAGAGTGGC GCGATGCAAC AGAGAAGAAT 
AAGGAGTTTC TCCCGCGTTT AGGAGCTACT ATTGAACATA TCTCAGTCTC GCCTGCAGGA 
GATTTATTCT GCACTTCTCA CTCTGATAAT AAGATAATAA TTATTCACCG AAACCTTGAA 
GCATCCGCAG TAATTCAAGG CCTAGTGAAA GATAGGAGTA TCTTCACTGG TTTGATGATT 
GATCCAAGAA CTAAAGCTTT GGTTTTGAAT GGAAAACCTG GCCACCTGCA GTTTTATTCT 
CTCCAGAGTG ATAAACAGTT ATACAATTTA GATATTATAC AGCAAGAATA TATTAATGAT 
TATGGTCTGA TCCAAATTGA ACTAACAAAG GCTGCATTTG GCTGCTTTGG TAACTGGCTT 
GCAACAGTGG AACAGCGGCA AGAAAAGGAA ACTGAGCTTG AATTGCAAAT GAAACTGTGG 
ATGTATAATA AGAAAACACA AGGGTTTATT CTTAACACTA AAATTAACAT GCCACACGAA 
GACTGCATTA CAGCTCTCTG TTTCTGTAAT GCAGAAAAAT CTGAACAGCC CACCTTGGTT 
ACAGCTAGCA AAGATGGTTA CTTCAAAGTA TGGATATTAA CAGATGACTC TGACATATAC 
AAAAAAGCTG TTGGCTGGAC CTGTGACTTT GTTGGTAGTT ATCACAAGTA TCAAGCAACT 
AACTGTTGTT TCTCCGAAGA TGGTTCTTTA CTAGCAGTTA GTTTTGAGGA AATAGTCACA 
ATATGGGATT CTGTAACATG GGAACTTAAA TGTACATTTT GCCAACGAGC TGGGAAAATA 
AGGCACCTTT GCTTTGGGAG ATTGACGTGT TCAAAGTATC TACTTGGTGC TACTGAAAAT 
GGCATTCTTT GCTGTTGGAA TCTGCTGAGC TGTGCATTGG AGTGGAATGC AAAATTAAAT 
GTTAGAGTTA TGGAACCCGA TCCTAATTCA GAGAATATTG CTGCAATCTC TCAGTCTTCA 
GTGGGTTCAG ACTTGTTTGT ATTTAAACCT AGTGAGCCAA GGCCATTGTA TATTCAAAAG 
GGTATCTCCA GAGAGAAAGT CCAGTGGGGA GTGTTTGTTC CACGAGATGT CCCTGAATCC 
TTCACCTCAG AAGCTTACCA GTGGCTAAAT AGATCCCAGT TTTACTTCCT AACAAAATCA 
CAGAGTTTAT TGACATTCAG TACAAAGTCT CCAGAAGAAA AACTCACACC AACAAGCAAA 
CAGCTGCTAG CAGAAGAAAG TCTTCCCACA ACCCCATTTT ATTTCATATT GGGAAAACAC 
AGGCAACAGC AGGATGAAAA ACTAAACGAA ACTTTAGAGA ATGAGCTGGT ACAACTACCC 
TTAACAGAAA ACATACCCGC AATTAGTGAG CTTCTTCACA CTCCAGCCCA TGTCCTGCCA 
TCTGCTGCTT TCCTGTGCTC CATGTTTGTA AATTCATTGC TGCTGTCTAA AGAGACTAAG 
AGTGCTAAGG AAATTCCTGA AGATGTAGAT ATGGAAGAAG AAAAAGAAAG TGAAGATTCA 
GATGAAGAAA ATGATTTTAC CGAAAAAGTC CAGGATACAA GTAACACAGG TTTAGGAGAA 
GACATTATAC ATCAGTTGTC AAAATCTGAA GAAAAAGAAC TGAGAAAATT TAGGAAAATA 
GACTACAGCT GGATAGCTGC CCTTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_024308936.1
CDS	2345..4171
Translation	MDGKIRLWRNFYDDKKYTYTCLHWHHDMVMDLAFSVTGTSLLSGGRESVLVEWRDATEKNKEFLPRLGATIEHISVSPAGDLFCTSHSDNKIIIIHRNLEASAVIQGLVKDRSIFTGLMIDPRTKALVLNGKPGHLQFYSLQSDKQLYNLDIIQQEYINDYGLIQIELTKAAFGCFGNWLATVEQRQEKETELELQMKLWMYNKKTQGFILNTKINMPHEDCITALCFCNAEKSEQPTLVTASKDGYFKVWILTDDSDIYKKAVGWTCDFVGSYHKYQATNCCFSEDGSLLAVSFEEIVTIWDSVTWELKCTFCQRAGKIRHLCFGRLTCSKYLLGATENGILCCWNLLSCALEWNAKLNVRVMEPDPNSENIAAISQSSVGSDLFVFKPSEPRPLYIQKGISREKVQWGVFVPRDVPESFTSEAYQWLNRSQFYFLTKSQSLLTFSTKSPEEKLTPTSKQLLAEESLPTTPFYFILGKHRQQQDEKLNETLENELVQLPLTENIPAISELLHTPAHVLPSAAFLCSMFVNSLLLSKETKSAKEIPEDVDMEEEKESEDSDEENDFTEKVQDTSNTGLGEDIIHQLSKSEEKELRKFRKIDYSWIAAL

Target ORF information:

RefSeq Version	XM_024453168.1
Organism	Homo sapiens(human)
Definition	Homo sapiens WD repeat domain 75 (WDR75), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_024453168.1

ORF Insert Sequence:

ATGGATGGCA AAATTCGTCT TTGGAGGAAT TTTTATGATG ATAAGAAATA TACGTACACA 
TGTTTACATT GGCACCATGA TATGGTTATG GATTTGGCTT TTTCAGTGAC AGGCACCAGT 
CTGCTGAGTG GCGGTCGTGA ATCTGTACTT GTAGAGTGGC GCGATGCAAC AGAGAAGAAT 
AAGGAGTTTC TCCCGCGTTT AGGAGCTACT ATTGAACATA TCTCAGTCTC GCCTGCAGGA 
GATTTATTCT GCACTTCTCA CTCTGATAAT AAGATAATAA TTATTCACCG AAACCTTGAA 
GCATCCGCAG TAATTCAAGG CCTAGTGAAA GATAGGAGTA TCTTCACTGG TTTGATGATT 
GATCCAAGAA CTAAAGCTTT GGTTTTGAAT GGAAAACCTG GCCACCTGCA GTTTTATTCT 
CTCCAGAGTG ATAAACAGTT ATACAATTTA GATATTATAC AGCAAGAATA TATTAATGAT 
TATGGTCTGA TCCAAATTGA ACTAACAAAG GCTGCATTTG GCTGCTTTGG TAACTGGCTT 
GCAACAGTGG AACAGCGGCA AGAAAAGGAA ACTGAGCTTG AATTGCAAAT GAAACTGTGG 
ATGTATAATA AGAAAACACA AGGGTTTATT CTTAACACTA AAATTAACAT GCCACACGAA 
GACTGCATTA CAGCTCTCTG TTTCTGTAAT GCAGAAAAAT CTGAACAGCC CACCTTGGTT 
ACAGCTAGCA AAGATGGTTA CTTCAAAGTA TGGATATTAA CAGATGACTC TGACATATAC 
AAAAAAGCTG TTGGCTGGAC CTGTGACTTT GTTGGTAGTT ATCACAAGTA TCAAGCAACT 
AACTGTTGTT TCTCCGAAGA TGGTTCTTTA CTAGCAGTTA GTTTTGAGGA AATAGTCACA 
ATATGGGATT CTGTAACATG GGAACTTAAA TGTACATTTT GCCAACGAGC TGGGAAAATA 
AGGCACCTTT GCTTTGGGAG ATTGACGTGT TCAAAGTATC TACTTGGTGC TACTGAAAAT 
GGCATTCTTT GCTGTTGGAA TCTGCTGAGC TGTGCATTGG AGTGGAATGC AAAATTAAAT 
GTTAGAGTTA TGGAACCCGA TCCTAATTCA GAGAATATTG CTGCAATCTC TCAGTCTTCA 
GTGGGTTCAG ACTTGTTTGT ATTTAAACCT AGTGAGCCAA GGCCATTGTA TATTCAAAAG 
GGTATCTCCA GAGAGAAAGT CCAGTGGGGA GTGTTTGTTC CACGAGATGT CCCTGAATCC 
TTCACCTCAG AAGCTTACCA GTGGCTAAAT AGATCCCAGT TTTACTTCCT AACAAAATCA 
CAGAGTTTAT TGACATTCAG TACAAAGTCT CCAGAAGAAA AACTCACACC AACAAGCAAA 
CAGCTGCTAG CAGAAGAAAG TCTTCCCACA ACCCCATTTT ATTTCATATT GGGAAAACAC 
AGGCAACAGC AGGATGAAAA ACTAAACGAA ACTTTAGAGA ATGAGCTGGT ACAACTACCC 
TTAACAGAAA ACATACCCGC AATTAGTGAG CTTCTTCACA CTCCAGCCCA TGTCCTGCCA 
TCTGCTGCTT TCCTGTGCTC CATGTTTGTA AATTCATTGC TGCTGTCTAA AGAGACTAAG 
AGTGCTAAGG AAATTCCTGA AGATGTAGAT ATGGAAGAAG AAAAAGAAAG TGAAGATTCA 
GATGAAGAAA ATGATTTTAC CGAAAAAGTC CAGGATACAA GTAACACAGG TTTAGGAGAA 
GACATTATAC ATCAGTTGTC AAAATCTGAA GAAAAAGAAC TGAGAAAATT TAGGAAAATA 
GACTACAGCT GGATAGCTGC CCTTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Novel loci affecting iron homeostasis and their effects in individuals at risk for hemochromatosis.
Nature communications54926(2014 Oct)
Benyamin B,Esko T,Ried JS,Radhakrishnan A,Vermeulen SH,Traglia M,G?gele M,Anderson D,Broer L,Podmore C,Luan J,Kutalik Z,Sanna S,van der Meer P,Tanaka T,Wang F,Westra HJ,Franke L,Mihailov E,Milani L,H?lldin J,H?ldin J,Winkelmann J,Meitinger T,Thiery J,Peters A,Waldenberger M,Rendon A,Jolley J,Sambrook J,Kiemeney LA,Sweep FC,Sala CF,Schwienbacher C,Pichler I,Hui J,Demirkan A,Isaacs A,Amin N,Steri M,Waeber G,Verweij N,Powell JE,Nyholt DR,Heath AC,Madden PA,Visscher PM,Wright MJ,Montgomery GW,Martin NG,Hernandez D,Bandinelli S,van der Harst P,Uda M,Vollenweider P,Scott RA,Langenberg C,Wareham NJ,,van Duijn C,Beilby J,Pramstaller PP,Hicks AA,Ouwehand WH,Oexle K,Gieger C,Metspalu A,Camaschella C,Toniolo D,Swinkels DW,Whitfield JB

Genome-wide RNAi screen identifies the Parkinson disease GWAS risk locus SREBF1 as a regulator of mitophagy.
Proceedings of the National Academy of Sciences of the United States of America111(23)8494-9(2014 Jun)
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WDR75 cDNA ORF clone, Homo sapiens(human)

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