TSSK1B cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	TSSK1B
Entrez Gene ID	83942
Full Name	testis specific serine kinase 1B
Synonyms	FKSG81,SPOGA4,STK22D,TSK1,TSSK1
General protein information	Preferred Names testis specific serine kinase 1B Names testis-specific serine/threonine-protein kinase 1 TSK-1 TSSK-1 serine/threonine kinase 22D (spermiogenesis associated) serine/threonine kinase FKSG81 serine/threonine-protein kinase 22A spermiogenesis associated 4 testis tissue sperm-binding protein Li 55e testis-specific kinase 1 testis-specific serine kinase 1
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 5 Map Location: 5q22.2
Summary	TSSK1 belongs to a family of serine/threonine kinases highly expressed in testis (Hao et al., 2004 [PubMed 15044604]).[supplied by OMIM, Mar 2008].
Disorder MIM:	610709

mRNA and Protein(s)

mRNA	Protein	Name
NM_032028.4	NP_114417.1	testis-specific serine/threonine-protein kinase 1
NM_032028.3	NP_114417.1	testis-specific serine/threonine-protein kinase 1

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	TSSK1B	XP_001145095.1
Bos taurus (cattle)	TSSK1B	NP_001077179.1
Canis lupus familiaris (dog)	TSSK1B	XP_543553.1
Rattus norvegicus (Norway rat)	Tssk1b	NP_001011900.1
Drosophila melanogaster (fruit fly)	CG14305	NP_650732.1
Homo sapiens (human)	TSSK1B	NP_114417.1
Mus musculus (house mouse)	Tssk1	NP_033461.2
Caenorhabditis elegans (roundworm)	CELE_C27D6.11	NP_001021995.1
Caenorhabditis elegans (roundworm)	tag-344	NP_492786.1
	TSSK1B	XP_002804522.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP010341	XP_001230821.2
Caenorhabditis elegans (roundworm)	CELE_Y38H8A.4	NP_502595.1

Gene Ontology
Bibliography

Related articles in PubMed

Evolution of testis-specific kinases TSSK1B and TSSK2 in primates.
Shang P, Hoogerbrugge J, Baarends WM, Grootegoed JA
Andrology1(1)160-8(2013 Jan)

Identification of peptide substrate and small molecule inhibitors of testis-specific serine/threonine kinase1 (TSSK1) by the developed assays.
Zhang L, Yan Y, Liu Z, Abliz Z, Liu G
Journal of medicinal chemistry52(14)4419-28(2009 Jul)

High-throughput mapping of a dynamic signaling network in mammalian cells.
Barrios-Rodiles M, Brown KR, Ozdamar B, Bose R, Liu Z, Donovan RS, Shinjo F, Liu Y, Dembowy J, Taylor IW, Luga V, Przulj N, Robinson M, Suzuki H, Hayashizaki Y, Jurisica I, Wrana JL
Science (New York, N.Y.)307(5715)1621-5(2005 Mar)

Identification of the sucrose non-fermenting related kinase SNRK, as a novel LKB1 substrate.
Jaleel M, McBride A, Lizcano JM, Deak M, Toth R, Morrice NA, Alessi DR
FEBS letters579(6)1417-23(2005 Feb)

Expression analysis of the human testis-specific serine/threonine kinase (TSSK) homologues. A TSSK member is present in the equatorial segment of human sperm.
Hao Z, Jha KN, Kim YH, Vemuganti S, Westbrook VA, Chertihin O, Markgraf K, Flickinger CJ, Coppola M, Herr JC, Visconti PE
Molecular human reproduction10(6)433-44(2004 Jun)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Report evolution of testis-specific kinases TSSK1B and TSSK2 in primates.
Title: Evolution of testis-specific kinases TSSK1B and TSSK2 in primates.

The following TSSK1B gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the TSSK1B cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu32072	NM_032028.4 Latest version!	Homo sapiens testis specific serine kinase 1B (TSSK1B), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
View Old Accession Versions >>
OHu32072	NM_032028.3	Homo sapiens testis specific serine kinase 1B (TSSK1B), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

TSSK1B ( NM_032028.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_114417.1 Homo sapiens testis specific serine kinase 1B (TSSK1B), mRNA.

Price & Availability↑

CloneID	OHu32072
Clone ID Related Accession (Same CDS sequence)	NM_032028.4 , NM_032028.3
Accession Version	NM_032028.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1104bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-24
Organism	Homo sapiens(human)
Product	testis-specific serine/threonine-protein kinase 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DB025324.1, BC022515.1, AK122904.1, DB527624.1 and AC010431.7. On May 17, 2019 this sequence version replaced NM_032028.3. ##Evidence-Data-START## Transcript is intronless :: AK122904.1, HM005678.1 [ECO:0000345] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000390666.4/ ENSP00000375081.3 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END##

ATGGATGACG CTGCTGTCCT CAAGCGACGA GGCTACCTCC TGGGGATAAA TTTAGGAGAG 
GGCTCCTATG CAAAAGTAAA ATCTGCTTAC TCTGAGCGCC TGAAGTTCAA TGTGGCGATC 
AAGATCATCG ACCGCAAGAA GGCCCCCGCA GACTTCTTGG AGAAATTCCT TCCCCGGGAA 
ATTGAGATTC TGGCCATGTT AAACCACTGC TCCATCATTA AGACCTACGA GATCTTTGAG 
ACATCACATG GCAAGGTCTA CATCGTCATG GAGCTCGCGG TCCAGGGCGA CCTCCTCGAG 
TTAATCAAAA CCCGGGGAGC CCTGCATGAG GACGAAGCTC GCAAGAAGTT CCACCAGCTT 
TCCTTGGCCA TCAAGTACTG CCACGACCTG GACGTCGTCC ACCGGGACCT CAAGTGTGAC 
AACCTTCTCC TTGACAAGGA CTTCAACATC AAGCTGTCCG ACTTCAGCTT CTCCAAGCGC 
TGCCTGCGGG ATGACAGTGG TCGAATGGCA TTAAGCAAGA CCTTCTGTGG GTCACCAGCG 
TATGCGGCCC CAGAGGTGCT GCAGGGCATT CCCTACCAGC CCAAGGTGTA CGACATCTGG 
AGCCTAGGCG TGATCCTCTA CATCATGGTC TGCGGCTCCA TGCCCTACGA CGACTCCAAC 
ATCAAGAAGA TGCTGCGTAT CCAGAAGGAG CACCGCGTCA ACTTCCCACG CTCCAAGCAC 
CTGACAGGCG AGTGCAAGGA CCTCATCTAC CACATGCTGC AGCCCGACGT CAACCGGCGG 
CTCCACATCG ACGAGATCCT CAGCCACTGC TGGATGCAGC CCAAGGCACG GGGATCTCCC 
TCTGTGGCCA TCAACAAGGA GGGGGAGAGT TCCCGGGGAA CTGAACCCTT GTGGACCCCC 
GAACCTGGCT CTGACAAGAA GTCTGCCACC AAGCTGGAGC CTGAGGGAGA GGCACAGCCC 
CAGGCACAGC CTGAGACAAA ACCCGAGGGG ACAGCAATGC AAATGTCCAG GCAGTCGGAG 
ATCCTGGGTT TCCCCAGCAA GCCGTCGACT ATGGAGACAG AGGAAGGGCC CCCCCAACAG 
CCTCCAGAGA CGCGGGCCCA GTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_114417.1
CDS	151..1254
Translation	MDDAAVLKRRGYLLGINLGEGSYAKVKSAYSERLKFNVAIKIIDRKKAPADFLEKFLPREIEILAMLNHCSIIKTYEIFETSHGKVYIVMELAVQGDLLELIKTRGALHEDEARKKFHQLSLAIKYCHDLDVVHRDLKCDNLLLDKDFNIKLSDFSFSKRCLRDDSGRMALSKTFCGSPAYAAPEVLQGIPYQPKVYDIWSLGVILYIMVCGSMPYDDSNIKKMLRIQKEHRVNFPRSKHLTGECKDLIYHMLQPDVNRRLHIDEILSHCWMQPKARGSPSVAINKEGESSRGTEPLWTPEPGSDKKSATKLEPEGEAQPQAQPETKPEGTAMQMSRQSEILGFPSKPSTMETEEGPPQQPPETRAQ

Target ORF information:

RefSeq Version	NM_032028.4
Organism	Homo sapiens(human)
Definition	Homo sapiens testis specific serine kinase 1B (TSSK1B), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_032028.4

ORF Insert Sequence:

ATGGATGACG CTGCTGTCCT CAAGCGACGA GGCTACCTCC TGGGGATAAA TTTAGGAGAG 
GGCTCCTATG CAAAAGTAAA ATCTGCTTAC TCTGAGCGCC TGAAGTTCAA TGTGGCGATC 
AAGATCATCG ACCGCAAGAA GGCCCCCGCA GACTTCTTGG AGAAATTCCT TCCCCGGGAA 
ATTGAGATTC TGGCCATGTT AAACCACTGC TCCATCATTA AGACCTACGA GATCTTTGAG 
ACATCACATG GCAAGGTCTA CATCGTCATG GAGCTCGCGG TCCAGGGCGA CCTCCTCGAG 
TTAATCAAAA CCCGGGGAGC CCTGCATGAG GACGAAGCTC GCAAGAAGTT CCACCAGCTT 
TCCTTGGCCA TCAAGTACTG CCACGACCTG GACGTCGTCC ACCGGGACCT CAAGTGTGAC 
AACCTTCTCC TTGACAAGGA CTTCAACATC AAGCTGTCCG ACTTCAGCTT CTCCAAGCGC 
TGCCTGCGGG ATGACAGTGG TCGAATGGCA TTAAGCAAGA CCTTCTGTGG GTCACCAGCG 
TATGCGGCCC CAGAGGTGCT GCAGGGCATT CCCTACCAGC CCAAGGTGTA CGACATCTGG 
AGCCTAGGCG TGATCCTCTA CATCATGGTC TGCGGCTCCA TGCCCTACGA CGACTCCAAC 
ATCAAGAAGA TGCTGCGTAT CCAGAAGGAG CACCGCGTCA ACTTCCCACG CTCCAAGCAC 
CTGACAGGCG AGTGCAAGGA CCTCATCTAC CACATGCTGC AGCCCGACGT CAACCGGCGG 
CTCCACATCG ACGAGATCCT CAGCCACTGC TGGATGCAGC CCAAGGCACG GGGATCTCCC 
TCTGTGGCCA TCAACAAGGA GGGGGAGAGT TCCCGGGGAA CTGAACCCTT GTGGACCCCC 
GAACCTGGCT CTGACAAGAA GTCTGCCACC AAGCTGGAGC CTGAGGGAGA GGCACAGCCC 
CAGGCACAGC CTGAGACAAA ACCCGAGGGG ACAGCAATGC AAATGTCCAG GCAGTCGGAG 
ATCCTGGGTT TCCCCAGCAA GCCGTCGACT ATGGAGACAG AGGAAGGGCC CCCCCAACAG 
CCTCCAGAGA CGCGGGCCCA GTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TSSK1B ( NM_032028.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_114417.1 Homo sapiens testis specific serine kinase 1B (TSSK1B), mRNA.

Price & Availability↑

CloneID	OHu32072
Clone ID Related Accession (Same CDS sequence)	NM_032028.4 , NM_032028.3
Accession Version	NM_032028.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1104bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-22
Organism	Homo sapiens(human)
Product	testis-specific serine/threonine-protein kinase 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DB025324.1, BC022515.1, AK122904.1 and DB527624.1. On May 28, 2009 this sequence version replaced NM_032028.2.

ATGGATGACG CTGCTGTCCT CAAGCGACGA GGCTACCTCC TGGGGATAAA TTTAGGAGAG 
GGCTCCTATG CAAAAGTAAA ATCTGCTTAC TCTGAGCGCC TGAAGTTCAA TGTGGCGATC 
AAGATCATCG ACCGCAAGAA GGCCCCCGCA GACTTCTTGG AGAAATTCCT TCCCCGGGAA 
ATTGAGATTC TGGCCATGTT AAACCACTGC TCCATCATTA AGACCTACGA GATCTTTGAG 
ACATCACATG GCAAGGTCTA CATCGTCATG GAGCTCGCGG TCCAGGGCGA CCTCCTCGAG 
TTAATCAAAA CCCGGGGAGC CCTGCATGAG GACGAAGCTC GCAAGAAGTT CCACCAGCTT 
TCCTTGGCCA TCAAGTACTG CCACGACCTG GACGTCGTCC ACCGGGACCT CAAGTGTGAC 
AACCTTCTCC TTGACAAGGA CTTCAACATC AAGCTGTCCG ACTTCAGCTT CTCCAAGCGC 
TGCCTGCGGG ATGACAGTGG TCGAATGGCA TTAAGCAAGA CCTTCTGTGG GTCACCAGCG 
TATGCGGCCC CAGAGGTGCT GCAGGGCATT CCCTACCAGC CCAAGGTGTA CGACATCTGG 
AGCCTAGGCG TGATCCTCTA CATCATGGTC TGCGGCTCCA TGCCCTACGA CGACTCCAAC 
ATCAAGAAGA TGCTGCGTAT CCAGAAGGAG CACCGCGTCA ACTTCCCACG CTCCAAGCAC 
CTGACAGGCG AGTGCAAGGA CCTCATCTAC CACATGCTGC AGCCCGACGT CAACCGGCGG 
CTCCACATCG ACGAGATCCT CAGCCACTGC TGGATGCAGC CCAAGGCACG GGGATCTCCC 
TCTGTGGCCA TCAACAAGGA GGGGGAGAGT TCCCGGGGAA CTGAACCCTT GTGGACCCCC 
GAACCTGGCT CTGACAAGAA GTCTGCCACC AAGCTGGAGC CTGAGGGAGA GGCACAGCCC 
CAGGCACAGC CTGAGACAAA ACCCGAGGGG ACAGCAATGC AAATGTCCAG GCAGTCGGAG 
ATCCTGGGTT TCCCCAGCAA GCCGTCGACT ATGGAGACAG AGGAAGGGCC CCCCCAACAG 
CCTCCAGAGA CGCGGGCCCA GTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_114417.1
CDS	193..1296
Translation	MDDAAVLKRRGYLLGINLGEGSYAKVKSAYSERLKFNVAIKIIDRKKAPADFLEKFLPREIEILAMLNHCSIIKTYEIFETSHGKVYIVMELAVQGDLLELIKTRGALHEDEARKKFHQLSLAIKYCHDLDVVHRDLKCDNLLLDKDFNIKLSDFSFSKRCLRDDSGRMALSKTFCGSPAYAAPEVLQGIPYQPKVYDIWSLGVILYIMVCGSMPYDDSNIKKMLRIQKEHRVNFPRSKHLTGECKDLIYHMLQPDVNRRLHIDEILSHCWMQPKARGSPSVAINKEGESSRGTEPLWTPEPGSDKKSATKLEPEGEAQPQAQPETKPEGTAMQMSRQSEILGFPSKPSTMETEEGPPQQPPETRAQ

Target ORF information:

RefSeq Version	NM_032028.3
Organism	Homo sapiens(human)
Definition	Homo sapiens testis specific serine kinase 1B (TSSK1B), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_032028.3

ORF Insert Sequence:

ATGGATGACG CTGCTGTCCT CAAGCGACGA GGCTACCTCC TGGGGATAAA TTTAGGAGAG 
GGCTCCTATG CAAAAGTAAA ATCTGCTTAC TCTGAGCGCC TGAAGTTCAA TGTGGCGATC 
AAGATCATCG ACCGCAAGAA GGCCCCCGCA GACTTCTTGG AGAAATTCCT TCCCCGGGAA 
ATTGAGATTC TGGCCATGTT AAACCACTGC TCCATCATTA AGACCTACGA GATCTTTGAG 
ACATCACATG GCAAGGTCTA CATCGTCATG GAGCTCGCGG TCCAGGGCGA CCTCCTCGAG 
TTAATCAAAA CCCGGGGAGC CCTGCATGAG GACGAAGCTC GCAAGAAGTT CCACCAGCTT 
TCCTTGGCCA TCAAGTACTG CCACGACCTG GACGTCGTCC ACCGGGACCT CAAGTGTGAC 
AACCTTCTCC TTGACAAGGA CTTCAACATC AAGCTGTCCG ACTTCAGCTT CTCCAAGCGC 
TGCCTGCGGG ATGACAGTGG TCGAATGGCA TTAAGCAAGA CCTTCTGTGG GTCACCAGCG 
TATGCGGCCC CAGAGGTGCT GCAGGGCATT CCCTACCAGC CCAAGGTGTA CGACATCTGG 
AGCCTAGGCG TGATCCTCTA CATCATGGTC TGCGGCTCCA TGCCCTACGA CGACTCCAAC 
ATCAAGAAGA TGCTGCGTAT CCAGAAGGAG CACCGCGTCA ACTTCCCACG CTCCAAGCAC 
CTGACAGGCG AGTGCAAGGA CCTCATCTAC CACATGCTGC AGCCCGACGT CAACCGGCGG 
CTCCACATCG ACGAGATCCT CAGCCACTGC TGGATGCAGC CCAAGGCACG GGGATCTCCC 
TCTGTGGCCA TCAACAAGGA GGGGGAGAGT TCCCGGGGAA CTGAACCCTT GTGGACCCCC 
GAACCTGGCT CTGACAAGAA GTCTGCCACC AAGCTGGAGC CTGAGGGAGA GGCACAGCCC 
CAGGCACAGC CTGAGACAAA ACCCGAGGGG ACAGCAATGC AAATGTCCAG GCAGTCGGAG 
ATCCTGGGTT TCCCCAGCAA GCCGTCGACT ATGGAGACAG AGGAAGGGCC CCCCCAACAG 
CCTCCAGAGA CGCGGGCCCA GTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Evolution of testis-specific kinases TSSK1B and TSSK2 in primates.
Andrology1(1)160-8(2013 Jan)
Shang P,Hoogerbrugge J,Baarends WM,Grootegoed JA

Identification of peptide substrate and small molecule inhibitors of testis-specific serine/threonine kinase1 (TSSK1) by the developed assays.
Journal of medicinal chemistry52(14)4419-28(2009 Jul)
Zhang L,Yan Y,Liu Z,Abliz Z,Liu G

High-throughput mapping of a dynamic signaling network in mammalian cells.
Science (New York, N.Y.)307(5715)1621-5(2005 Mar)
Barrios-Rodiles M,Brown KR,Ozdamar B,Bose R,Liu Z,Donovan RS,Shinjo F,Liu Y,Dembowy J,Taylor IW,Luga V,Przulj N,Robinson M,Suzuki H,Hayashizaki Y,Jurisica I,Wrana JL

Identification of the sucrose non-fermenting related kinase SNRK, as a novel LKB1 substrate.
FEBS letters579(6)1417-23(2005 Feb)
Jaleel M,McBride A,Lizcano JM,Deak M,Toth R,Morrice NA,Alessi DR

Expression analysis of the human testis-specific serine/threonine kinase (TSSK) homologues. A TSSK member is present in the equatorial segment of human sperm.
Molecular human reproduction10(6)433-44(2004 Jun)
Hao Z,Jha KN,Kim YH,Vemuganti S,Westbrook VA,Chertihin O,Markgraf K,Flickinger CJ,Coppola M,Herr JC,Visconti PE

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TSSK1B cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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