OR3A3 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	OR3A3
Entrez Gene ID	8392
Full Name	olfactory receptor family 3 subfamily A member 3
Synonyms	OR17-137,OR17-16,OR17-201,OR3A6,OR3A7,OR3A8P
General protein information	Preferred Names olfactory receptor family 3 subfamily A member 3 Names olfactory receptor 3A3 olfactory receptor 17-201 olfactory receptor 3A6 olfactory receptor 3A7 olfactory receptor 3A8 olfactory receptor OR17-22 olfactory receptor, family 3, subfamily A, member 6 olfactory receptor, family 3, subfamily A, member 7 olfactory receptor, family 3, subfamily A, member 8 pseudogene
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 17 Map Location: 17p13.2
Summary	Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008].

mRNA and Protein(s)

mRNA	Protein	Name
NM_012373.2	NP_036505.2	olfactory receptor 3A3
XM_011524028.2	XP_011522330.1	olfactory receptor 3A3 isoform X1

Pathways from BioSystems

Homologies

Homo sapiens (human)	OR3A3	NP_036505.2
	LOC721444	XP_001117593.2
Bos taurus (cattle)	LOC508980	XP_003587449.1
Pan troglodytes (chimpanzee)	LOC454428	XP_511266.3
Canis lupus familiaris (dog)	OR01E11	XP_548333.1
Mus musculus (house mouse)	Olfr411	NP_666920.2

Gene Ontology
Bibliography

Related articles in PubMed

DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage.
Zody MC, Garber M, Adams DJ, Sharpe T, Harrow J, Lupski JR, Nicholson C, Searle SM, Wilming L, Young SK, Abouelleil A, Allen NR, Bi W, Bloom T, Borowsky ML, Bugalter BE, Butler J, Chang JL, Chen CK, Cook A, Corum B, Cuomo CA, de Jong PJ, DeCaprio D, Dewar K, FitzGerald M, Gilbert J, Gibson R, Gnerre S, Goldstein S, Grafham DV, Grocock R, Hafez N, Hagopian DS, Hart E, Norman CH, Humphray S, Jaffe DB, Jones M, Kamal M, Khodiyar VK, LaButti K, Laird G, Lehoczky J, Liu X, Lokyitsang T, Loveland J, Lui A, Macdonald P, Major JE, Matthews L, Mauceli E, McCarroll SA, Mihalev AH, Mudge J, Nguyen C, Nicol R, O'Leary SB, Osoegawa K, Schwartz DC, Shaw-Smith C, Stankiewicz P, Steward C, Swarbreck D, Venkataraman V, Whittaker CA, Yang X, Zimmer AR, Bradley A, Hubbard T, Birren BW, Rogers J, Lander ES, Nusbaum C
Nature440(7087)1045-9(2006 Apr)

The human olfactory receptor gene family.
Malnic B, Godfrey PA, Buck LB
Proceedings of the National Academy of Sciences of the United States of America101(8)2584-9(2004 Feb)

Population differences in the human functional olfactory repertoire.
Gilad Y, Lancet D
Molecular biology and evolution20(3)307-14(2003 Mar)

DEFOG: a practical scheme for deciphering families of genes.
Fuchs T, Malecova B, Linhart C, Sharan R, Khen M, Herwig R, Shmulevich D, Elkon R, Steinfath M, O'Brien JK, Radelof U, Lehrach H, Lancet D, Shamir R
Genomics80(3)295-302(2002 Sep)

Sequence, structure, and evolution of a complete human olfactory receptor gene cluster.
Glusman G, Sosinsky A, Ben-Asher E, Avidan N, Sonkin D, Bahar A, Rosenthal A, Clifton S, Roe B, Ferraz C, Demaille J, Lancet D
Genomics63(2)227-45(2000 Jan)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)
Title: Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.

The following OR3A3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the OR3A3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OHu00272	NM_012373.2 Latest version!	Homo sapiens olfactory receptor family 3 subfamily A member 3 (OR3A3), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$99.50-$139.30 $199.00
OHu61721	XM_011524028.2 Latest version!	Homo sapiens olfactory receptor family 3 subfamily A member 3 (OR3A3), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

OR3A3 ( NM_012373.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_036505.2 Homo sapiens olfactory receptor family 3 subfamily A member 3 (OR3A3), mRNA.

Price & Availability↑

CloneID	OHu00272
Clone ID Related Accession (Same CDS sequence)	NM_012373.2
Accession Version	NM_012373.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 966bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-23
Organism	Homo sapiens(human)
Product	olfactory receptor 3A3
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC025125.15. On Feb 24, 2010 this sequence version replaced NM_012373.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript is intronless :: BC069415.1, BC108921.2 [ECO:0000345] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on conservation, longest protein ##RefSeq-Attributes-END##

ATGTCCTTAC AGAAACTCAT GGAGCCAGAA GCTGGGACCA ATAGGACCGC TGTTGCTGAG 
TTCATTCTAC TGGGCCTAGT GCAAACAGAA GAGATGCAGC CAGTTGTCTT TGTGCTCCTC 
CTCTTTGCCT ATCTGGTCAC AACTGGGGGC AACCTCAGCA TCCTGGCAGC CGTCTTGGTG 
GAGCCCAAAC TCCACGCCCC CATGTACTTC TTCCTGGGGA ACCTGTCAGT GCTGGATGTC 
GGATGTATCA CTGTCACTGT TCCTGCAATG TTGGGTCGTC TCTTGTCCCA CAAGTCCACA 
ATTTCCTATG ACGCCTGCCT CTCCCAGCTC TTCTTCTTCC ACCTTCTGGC TGGGATGGAC 
TGCTTCCTGC TGACCGCCAT GGCCTATGAC CGACTCCTGG CCATCTGCCA GCCCCTCACC 
TACAGCACCC GCATGAGTCA GACAGTCCAG AGGATGTTGG TGGCTGCGTC CTGGGCTTGT 
GCCTTCACCA ACGCACTGAC CCACACTGTG GCCATGTCCA CGCTCAACTT CTGTGGCCCC 
AATGAGGTCA ATCACTTCTA CTGTGACCTC CCACAGCTCT TCCAGCTCTC CTGCTCCAGC 
ACCCAACTCA ATGAGCTGCT GCTCTTTGTA GCAGCAGCCT TCATGGCTGT GGCACCCTTG 
GTCTTCATCA GTGTGTCCTA TGCCCATGTG GTAGCTGCTG TGCTGCAAAT CCGCTCTGCT 
GAGGGCAGAA AGAAGGCCTT CTCCACATGT GGCTCCCACC TCACTGTGGT GGGCATCTTC 
TATGGGACAG GTGTCTTCAG CTACATGAGG CTGGGTTCAG TGGAATCTTC AGACAAGGAT 
AAGGGGGTTG GGGTTTTCAT GACTGTGATC AACCCCATGC TGAACCCACT TATCTACAGC 
CTCAGAAATA CTGATGTTCA GGGCGCTCTG TGTCAGCTAC TTGTGGGGAA GCGATCACTG 
ACCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_036505.2
CDS	1..966
Translation	MSLQKLMEPEAGTNRTAVAEFILLGLVQTEEMQPVVFVLLLFAYLVTTGGNLSILAAVLVEPKLHAPMYFFLGNLSVLDVGCITVTVPAMLGRLLSHKSTISYDACLSQLFFFHLLAGMDCFLLTAMAYDRLLAICQPLTYSTRMSQTVQRMLVAASWACAFTNALTHTVAMSTLNFCGPNEVNHFYCDLPQLFQLSCSSTQLNELLLFVAAAFMAVAPLVFISVSYAHVVAAVLQIRSAEGRKKAFSTCGSHLTVVGIFYGTGVFSYMRLGSVESSDKDKGVGVFMTVINPMLNPLIYSLRNTDVQGALCQLLVGKRSLT

Target ORF information:

RefSeq Version	NM_012373.2
Organism	Homo sapiens(human)
Definition	Homo sapiens olfactory receptor family 3 subfamily A member 3 (OR3A3), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_012373.2

ORF Insert Sequence:

ATGTCCTTAC AGAAACTCAT GGAGCCAGAA GCTGGGACCA ATAGGACCGC TGTTGCTGAG 
TTCATTCTAC TGGGCCTAGT GCAAACAGAA GAGATGCAGC CAGTTGTCTT TGTGCTCCTC 
CTCTTTGCCT ATCTGGTCAC AACTGGGGGC AACCTCAGCA TCCTGGCAGC CGTCTTGGTG 
GAGCCCAAAC TCCACGCCCC CATGTACTTC TTCCTGGGGA ACCTGTCAGT GCTGGATGTC 
GGATGTATCA CTGTCACTGT TCCTGCAATG TTGGGTCGTC TCTTGTCCCA CAAGTCCACA 
ATTTCCTATG ACGCCTGCCT CTCCCAGCTC TTCTTCTTCC ACCTTCTGGC TGGGATGGAC 
TGCTTCCTGC TGACCGCCAT GGCCTATGAC CGACTCCTGG CCATCTGCCA GCCCCTCACC 
TACAGCACCC GCATGAGTCA GACAGTCCAG AGGATGTTGG TGGCTGCGTC CTGGGCTTGT 
GCCTTCACCA ACGCACTGAC CCACACTGTG GCCATGTCCA CGCTCAACTT CTGTGGCCCC 
AATGAGGTCA ATCACTTCTA CTGTGACCTC CCACAGCTCT TCCAGCTCTC CTGCTCCAGC 
ACCCAACTCA ATGAGCTGCT GCTCTTTGTA GCAGCAGCCT TCATGGCTGT GGCACCCTTG 
GTCTTCATCA GTGTGTCCTA TGCCCATGTG GTAGCTGCTG TGCTGCAAAT CCGCTCTGCT 
GAGGGCAGAA AGAAGGCCTT CTCCACATGT GGCTCCCACC TCACTGTGGT GGGCATCTTC 
TATGGGACAG GTGTCTTCAG CTACATGAGG CTGGGTTCAG TGGAATCTTC AGACAAGGAT 
AAGGGGGTTG GGGTTTTCAT GACTGTGATC AACCCCATGC TGAACCCACT TATCTACAGC 
CTCAGAAATA CTGATGTTCA GGGCGCTCTG TGTCAGCTAC TTGTGGGGAA GCGATCACTG 
ACCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

OR3A3 ( XM_011524028.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011522330.1 Homo sapiens olfactory receptor family 3 subfamily A member 3 (OR3A3), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu61721
Clone ID Related Accession (Same CDS sequence)	XM_011524028.2
Accession Version	XM_011524028.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 948bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	olfactory receptor 3A3 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000017.11) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011524028.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAGCCAG AAGCTGGGAC CAATAGGACC GCTGTTGCTG AGTTCATTCT ACTGGGCCTA 
GTGCAAACAG AAGAGATGCA GCCAGTTGTC TTTGTGCTCC TCCTCTTTGC CTATCTGGTC 
ACAACTGGGG GCAACCTCAG CATCCTGGCA GCCGTCTTGG TGGAGCCCAA ACTCCACGCC 
CCCATGTACT TCTTCCTGGG GAACCTGTCA GTGCTGGATG TCGGATGTAT CACTGTCACT 
GTTCCTGCAA TGTTGGGTCG TCTCTTGTCC CACAAGTCCA CAATTTCCTA TGACGCCTGC 
CTCTCCCAGC TCTTCTTCTT CCACCTTCTG GCTGGGATGG ACTGCTTCCT GCTGACCGCC 
ATGGCCTATG ACCGACTCCT GGCCATCTGC CAGCCCCTCA CCTACAGCAC CCGCATGAGT 
CAGACAGTCC AGAGGATGTT GGTGGCTGCG TCCTGGGCTT GTGCCTTCAC CAACGCACTG 
ACCCACACTG TGGCCATGTC CACGCTCAAC TTCTGTGGCC CCAATGAGGT CAATCACTTC 
TACTGTGACC TCCCACAGCT CTTCCAGCTC TCCTGCTCCA GCACCCAACT CAATGAGCTG 
CTGCTCTTTG TAGCAGCAGC CTTCATGGCT GTGGCACCCT TGGTCTTCAT CAGTGTGTCC 
TATGCCCATG TGGTAGCTGC TGTGCTGCAA ATCCGCTCTG CTGAGGGCAG AAAGAAGGCC 
TTCTCCACAT GTGGCTCCCA CCTCACTGTG GTGGGCATCT TCTATGGGAC AGGTGTCTTC 
AGCTACATGA GGCTGGGTTC AGTGGAATCT TCAGACAAGG ATAAGGGGGT TGGGGTTTTC 
ATGACTGTGA TCAACCCCAT GCTGAACCCA CTTATCTACA GCCTCAGAAA TACTGATGTT 
CAGGGCGCTC TGTGTCAGCT ACTTGTGGGG AAGCGATCAC TGACCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011522330.1
CDS	29..976
Translation	MEPEAGTNRTAVAEFILLGLVQTEEMQPVVFVLLLFAYLVTTGGNLSILAAVLVEPKLHAPMYFFLGNLSVLDVGCITVTVPAMLGRLLSHKSTISYDACLSQLFFFHLLAGMDCFLLTAMAYDRLLAICQPLTYSTRMSQTVQRMLVAASWACAFTNALTHTVAMSTLNFCGPNEVNHFYCDLPQLFQLSCSSTQLNELLLFVAAAFMAVAPLVFISVSYAHVVAAVLQIRSAEGRKKAFSTCGSHLTVVGIFYGTGVFSYMRLGSVESSDKDKGVGVFMTVINPMLNPLIYSLRNTDVQGALCQLLVGKRSLT

Target ORF information:

RefSeq Version	XM_011524028.2
Organism	Homo sapiens(human)
Definition	Homo sapiens olfactory receptor family 3 subfamily A member 3 (OR3A3), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011524028.2

ORF Insert Sequence:

ATGGAGCCAG AAGCTGGGAC CAATAGGACC GCTGTTGCTG AGTTCATTCT ACTGGGCCTA 
GTGCAAACAG AAGAGATGCA GCCAGTTGTC TTTGTGCTCC TCCTCTTTGC CTATCTGGTC 
ACAACTGGGG GCAACCTCAG CATCCTGGCA GCCGTCTTGG TGGAGCCCAA ACTCCACGCC 
CCCATGTACT TCTTCCTGGG GAACCTGTCA GTGCTGGATG TCGGATGTAT CACTGTCACT 
GTTCCTGCAA TGTTGGGTCG TCTCTTGTCC CACAAGTCCA CAATTTCCTA TGACGCCTGC 
CTCTCCCAGC TCTTCTTCTT CCACCTTCTG GCTGGGATGG ACTGCTTCCT GCTGACCGCC 
ATGGCCTATG ACCGACTCCT GGCCATCTGC CAGCCCCTCA CCTACAGCAC CCGCATGAGT 
CAGACAGTCC AGAGGATGTT GGTGGCTGCG TCCTGGGCTT GTGCCTTCAC CAACGCACTG 
ACCCACACTG TGGCCATGTC CACGCTCAAC TTCTGTGGCC CCAATGAGGT CAATCACTTC 
TACTGTGACC TCCCACAGCT CTTCCAGCTC TCCTGCTCCA GCACCCAACT CAATGAGCTG 
CTGCTCTTTG TAGCAGCAGC CTTCATGGCT GTGGCACCCT TGGTCTTCAT CAGTGTGTCC 
TATGCCCATG TGGTAGCTGC TGTGCTGCAA ATCCGCTCTG CTGAGGGCAG AAAGAAGGCC 
TTCTCCACAT GTGGCTCCCA CCTCACTGTG GTGGGCATCT TCTATGGGAC AGGTGTCTTC 
AGCTACATGA GGCTGGGTTC AGTGGAATCT TCAGACAAGG ATAAGGGGGT TGGGGTTTTC 
ATGACTGTGA TCAACCCCAT GCTGAACCCA CTTATCTACA GCCTCAGAAA TACTGATGTT 
CAGGGCGCTC TGTGTCAGCT ACTTGTGGGG AAGCGATCAC TGACCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage.
Nature440(7087)1045-9(2006 Apr)
Zody MC,Garber M,Adams DJ,Sharpe T,Harrow J,Lupski JR,Nicholson C,Searle SM,Wilming L,Young SK,Abouelleil A,Allen NR,Bi W,Bloom T,Borowsky ML,Bugalter BE,Butler J,Chang JL,Chen CK,Cook A,Corum B,Cuomo CA,de Jong PJ,DeCaprio D,Dewar K,FitzGerald M,Gilbert J,Gibson R,Gnerre S,Goldstein S,Grafham DV,Grocock R,Hafez N,Hagopian DS,Hart E,Norman CH,Humphray S,Jaffe DB,Jones M,Kamal M,Khodiyar VK,LaButti K,Laird G,Lehoczky J,Liu X,Lokyitsang T,Loveland J,Lui A,Macdonald P,Major JE,Matthews L,Mauceli E,McCarroll SA,Mihalev AH,Mudge J,Nguyen C,Nicol R,O'Leary SB,Osoegawa K,Schwartz DC,Shaw-Smith C,Stankiewicz P,Steward C,Swarbreck D,Venkataraman V,Whittaker CA,Yang X,Zimmer AR,Bradley A,Hubbard T,Birren BW,Rogers J,Lander ES,Nusbaum C

The human olfactory receptor gene family.
Proceedings of the National Academy of Sciences of the United States of America101(8)2584-9(2004 Feb)
Malnic B,Godfrey PA,Buck LB

Population differences in the human functional olfactory repertoire.
Molecular biology and evolution20(3)307-14(2003 Mar)
Gilad Y,Lancet D

DEFOG: a practical scheme for deciphering families of genes.
Genomics80(3)295-302(2002 Sep)
Fuchs T,Malecova B,Linhart C,Sharan R,Khen M,Herwig R,Shmulevich D,Elkon R,Steinfath M,O'Brien JK,Radelof U,Lehrach H,Lancet D,Shamir R

Sequence, structure, and evolution of a complete human olfactory receptor gene cluster.
Genomics63(2)227-45(2000 Jan)
Glusman G,Sosinsky A,Ben-Asher E,Avidan N,Sonkin D,Bahar A,Rosenthal A,Clifton S,Roe B,Ferraz C,Demaille J,Lancet D

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OR3A3 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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