KRTAP17-1 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	KRTAP17-1
Entrez Gene ID	83902
Full Name	keratin associated protein 17-1
Synonyms	KAP17.1,KRTAP16.1,KRTAP17.1
General protein information	Preferred Names keratin associated protein 17-1 Names keratin-associated protein 17-1 keratin associated protein 16.1
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 17 Map Location: 17q21.2
Summary	This protein is a member of the keratin-associated protein (KAP) family. The KAP proteins form a matrix of keratin intermediate filaments which contribute to the structure of hair fibers. KAP family members appear to have unique, family-specific amino- and carboxyl-terminal regions and are subdivided into three multi-gene families according to amino acid composition: the high sulfur, the ultrahigh sulfur, and the high tyrosine/glycine KAPs. This protein is a member of the ultrahigh sulfur KAP family and the gene is localized to a cluster of KAPs at 17q12-q21. [provided by RefSeq, Jul 2008].

mRNA and Protein(s)

mRNA	Protein	Name
NM_031964.2	NP_114170.1	keratin-associated protein 17-1
NM_031964.1	NP_114170.1	keratin-associated protein 17-1

Pathways from BioSystems

Homologies

Homo sapiens (human)	KRTAP17-1	NP_114170.1
Pan troglodytes (chimpanzee)	LOC742258	XP_001145354.2

Gene Ontology
Bibliography

Related articles in PubMed

Recurrent mutation in keratin 17 in a large family with pachyonychia congenita type 2.
Oh Adib C, Jones B, Liao H, Smith FJ, Solomon R, Egan CA, Leachman S
Archives of dermatological research300(5)211-4(2008 Jun)

Characterization of a cluster of human high/ultrahigh sulfur keratin-associated protein genes embedded in the type I keratin gene domain on chromosome 17q12-21.
Rogers MA, Langbein L, Winter H, Ehmann C, Praetzel S, Korn B, Schweizer J
The Journal of biological chemistry276(22)19440-51(2001 Jun)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)
Title: Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.

Recurrent mutation in a large family with pachyonychia congenita type 2
Title: Recurrent mutation in keratin 17 in a large family with pachyonychia congenita type 2.

The following KRTAP17-1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the KRTAP17-1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu29294	NM_031964.2 Latest version!	Homo sapiens keratin associated protein 17-1 (KRTAP17-1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
View Old Accession Versions >>
OHu29294	NM_031964.1	Homo sapiens keratin associated protein 17-1 (KRTAP17-1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$69.30 $99.00
Hide Old Accession Versions >>

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

KRTAP17-1 ( NM_031964.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_114170.1 Homo sapiens keratin associated protein 17-1 (KRTAP17-1), mRNA.

Price & Availability↑

CloneID	OHu29294
Clone ID Related Accession (Same CDS sequence)	NM_031964.2 , NM_031964.1
Accession Version	NM_031964.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 318bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-20
Organism	Homo sapiens(human)
Product	keratin-associated protein 17-1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff in collaboration with Michael Rogers. The reference sequence was derived from AC003958.3 and AJ406952.1. On May 17, 2019 this sequence version replaced NM_031964.1. ##Evidence-Data-START## Transcript is intronless :: AJ406952.1, BC069078.1 [ECO:0000345] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000334202.5/ ENSP00000333993.3 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGGGTGCT GCCCGGGGGA CTGCTTCACC TGCTGCACCC AGGAGCAAAA CTGCTGTGAA 
GAGTGCTGCT GTCAGCCGGG CTGCTGTGGC TGCTGCGGCT CCTGCTGTGG CTGTGGGGGC 
TCTGGCTGCG GGGGCTCTGG CTGCGGGGGC AGCTGCTGCG GATCGTCTTG CTGTGGATCT 
GGCTGCGGAG GCTGTGGAGG CTGCGGAGGC TGCGGGGGTG GCTGCTGTGG ATCCAGTTGC 
TGTGGGTCCA GTTGCTGCGG CTCCGGGTGC TGTGGGCCTG TGTGCTGCCA GCCCACACCT 
ATATGCGACA CAAAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_114170.1
CDS	61..378
Translation	MGCCPGDCFTCCTQEQNCCEECCCQPGCCGCCGSCCGCGGSGCGGSGCGGSCCGSSCCGSGCGGCGGCGGCGGGCCGSSCCGSSCCGSGCCGPVCCQPTPICDTK

Target ORF information:

RefSeq Version	NM_031964.2
Organism	Homo sapiens(human)
Definition	Homo sapiens keratin associated protein 17-1 (KRTAP17-1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_031964.2

ORF Insert Sequence:

ATGGGGTGCT GCCCGGGGGA CTGCTTCACC TGCTGCACCC AGGAGCAAAA CTGCTGTGAA 
GAGTGCTGCT GTCAGCCGGG CTGCTGTGGC TGCTGCGGCT CCTGCTGTGG CTGTGGGGGC 
TCTGGCTGCG GGGGCTCTGG CTGCGGGGGC AGCTGCTGCG GATCGTCTTG CTGTGGATCT 
GGCTGCGGAG GCTGTGGAGG CTGCGGAGGC TGCGGGGGTG GCTGCTGTGG ATCCAGTTGC 
TGTGGGTCCA GTTGCTGCGG CTCCGGGTGC TGTGGGCCTG TGTGCTGCCA GCCCACACCT 
ATATGCGACA CAAAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

KRTAP17-1 ( NM_031964.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_114170.1 Homo sapiens keratin associated protein 17-1 (KRTAP17-1), mRNA.

Price & Availability↑

CloneID	OHu29294
Clone ID Related Accession (Same CDS sequence)	NM_031964.2 , NM_031964.1
Accession Version	NM_031964.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 318bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-06-22
Organism	Homo sapiens(human)
Product	keratin-associated protein 17-1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff in collaboration with Michael Rogers. The reference sequence was derived from AJ406952.1. On Sep 21, 2006 this sequence version replaced XM_001127267.1. ##Evidence-Data-START## Transcript is intronless :: AJ406952.1 [ECO:0000345] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGGGTGCT GCCCGGGGGA CTGCTTCACC TGCTGCACCC AGGAGCAAAA CTGCTGTGAA 
GAGTGCTGCT GTCAGCCGGG CTGCTGTGGC TGCTGCGGCT CCTGCTGTGG CTGTGGGGGC 
TCTGGCTGCG GGGGCTCTGG CTGCGGGGGC AGCTGCTGCG GATCGTCTTG CTGTGGATCT 
GGCTGCGGAG GCTGTGGAGG CTGCGGAGGC TGCGGGGGTG GCTGCTGTGG ATCCAGTTGC 
TGTGGGTCCA GTTGCTGCGG CTCCGGGTGC TGTGGGCCTG TGTGCTGCCA GCCCACACCT 
ATATGCGACA CAAAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_114170.1
CDS	46..363
Translation	MGCCPGDCFTCCTQEQNCCEECCCQPGCCGCCGSCCGCGGSGCGGSGCGGSCCGSSCCGSGCGGCGGCGGCGGGCCGSSCCGSSCCGSGCCGPVCCQPTPICDTK

Target ORF information:

RefSeq Version	NM_031964.1
Organism	Homo sapiens(human)
Definition	Homo sapiens keratin associated protein 17-1 (KRTAP17-1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_031964.1

ORF Insert Sequence:

ATGGGGTGCT GCCCGGGGGA CTGCTTCACC TGCTGCACCC AGGAGCAAAA CTGCTGTGAA 
GAGTGCTGCT GTCAGCCGGG CTGCTGTGGC TGCTGCGGCT CCTGCTGTGG CTGTGGGGGC 
TCTGGCTGCG GGGGCTCTGG CTGCGGGGGC AGCTGCTGCG GATCGTCTTG CTGTGGATCT 
GGCTGCGGAG GCTGTGGAGG CTGCGGAGGC TGCGGGGGTG GCTGCTGTGG ATCCAGTTGC 
TGTGGGTCCA GTTGCTGCGG CTCCGGGTGC TGTGGGCCTG TGTGCTGCCA GCCCACACCT 
ATATGCGACA CAAAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Recurrent mutation in keratin 17 in a large family with pachyonychia congenita type 2.
Archives of dermatological research300(5)211-4(2008 Jun)
Oh Adib C,Jones B,Liao H,Smith FJ,Solomon R,Egan CA,Leachman S

Characterization of a cluster of human high/ultrahigh sulfur keratin-associated protein genes embedded in the type I keratin gene domain on chromosome 17q12-21.
The Journal of biological chemistry276(22)19440-51(2001 Jun)
Rogers MA,Langbein L,Winter H,Ehmann C,Praetzel S,Korn B,Schweizer J

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KRTAP17-1 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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