Gene Symbol | MAD1L1 |
Entrez Gene ID | 8379 |
Full Name | mitotic arrest deficient 1 like 1 |
Synonyms | MAD1,PIG9,TP53I9,TXBP181 |
General protein information |
|
Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Summary | MAD1L1 is a component of the mitotic spindle-assembly checkpoint that prevents the onset of anaphase until all chromosome are properly aligned at the metaphase plate. MAD1L1 functions as a homodimer and interacts with MAD2L1. MAD1L1 may play a role in cell cycle control and tumor suppression. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015]. |
Disorder MIM: | |
Disorder Html: | Lymphoma, somatic (3); Prostate cancer, somatic, 176807 (3) |