KRTAP4-12 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	KRTAP4-12
Entrez Gene ID	83755
Full Name	keratin associated protein 4-12
Synonyms	KAP4.12,KRTAP4.12
General protein information	Preferred Names keratin associated protein 4-12 Names keratin-associated protein 4-12 keratin-associated protein 4.12 ultrahigh sulfur keratin-associated protein 4.12
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 17 Map Location: 17q21.2
Summary	This protein is a member of the keratin-associated protein (KAP) family. The KAP proteins form a matrix of keratin intermediate filaments which contribute to the structure of hair fibers. KAP family members appear to have unique, family-specific amino- and carboxyl-terminal regions and are subdivided into three multi-gene families according to amino acid composition: the high sulfur, the ultrahigh sulfur, and the high tyrosine/glycine KAPs. This protein is a member of the ultrahigh sulfur KAP family and the gene is localized to a cluster of KAPs at 17q12-q21. [provided by RefSeq, Jul 2008].

mRNA and Protein(s)

mRNA	Protein	Name
NM_031854.2	NP_114060.1	keratin-associated protein 4-12
NM_031854.3	NP_114060.1	keratin-associated protein 4-12

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	LOC468249	XP_523640.3
Homo sapiens (human)	KRTAP4-12	NP_114060.1

Gene Ontology
Bibliography

Related articles in PubMed

An inter-species protein-protein interaction network across vast evolutionary distance.
Zhong Q, Pevzner SJ, Hao T, Wang Y, Mosca R, Menche J, Taipale M, Ta?an M, Fan C, Yang X, Haley P, Murray RR, Mer F, Gebreab F, Tam S, MacWilliams A, Dricot A, Reichert P, Santhanam B, Ghamsari L, Calderwood MA, Rolland T, Charloteaux B, Lindquist S, Barab?si AL, Hill DE, Aloy P, Cusick ME, Xia Y, Roth FP, Vidal M
Molecular systems biology12(4)865(2016 Apr)

Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing.
Yang X, Coulombe-Huntington J, Kang S, Sheynkman GM, Hao T, Richardson A, Sun S, Yang F, Shen YA, Murray RR, Spirohn K, Begg BE, Duran-Frigola M, MacWilliams A, Pevzner SJ, Zhong Q, Trigg SA, Tam S, Ghamsari L, Sahni N, Yi S, Rodriguez MD, Balcha D, Tan G, Costanzo M, Andrews B, Boone C, Zhou XJ, Salehi-Ashtiani K, Charloteaux B, Chen AA, Calderwood MA, Aloy P, Roth FP, Hill DE, Iakoucheva LM, Xia Y, Vidal M
Cell164(4)805-17(2016 Feb)

Protein interactions of the transcription factor Hoxa1.
Lambert B, Vandeputte J, Remacle S, Bergiers I, Simonis N, Twizere JC, Vidal M, Rezsohazy R
BMC developmental biology1229(2012 Oct)

A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration.
Lim J, Hao T, Shaw C, Patel AJ, Szab? G, Rual JF, Fisk CJ, Li N, Smolyar A, Hill DE, Barab?si AL, Vidal M, Zoghbi HY
Cell125(4)801-14(2006 May)

Characterization of a cluster of human high/ultrahigh sulfur keratin-associated protein genes embedded in the type I keratin gene domain on chromosome 17q12-21.
Rogers MA, Langbein L, Winter H, Ehmann C, Praetzel S, Korn B, Schweizer J
The Journal of biological chemistry276(22)19440-51(2001 Jun)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following KRTAP4-12 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the KRTAP4-12 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu29331	NM_031854.3 Latest version!	Homo sapiens keratin associated protein 4-12 (KRTAP4-12), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$134.50-$188.30 $269.00
View Old Accession Versions >>
OHu29331	NM_031854.2	Homo sapiens keratin associated protein 4-12 (KRTAP4-12), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$134.50-$188.30 $269.00
Hide Old Accession Versions >>

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

KRTAP4-12 ( NM_031854.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_114060.1 Homo sapiens keratin associated protein 4-12 (KRTAP4-12), mRNA.

Price & Availability↑

CloneID	OHu29331
Clone ID Related Accession (Same CDS sequence)	NM_031854.2 , NM_031854.3
Accession Version	NM_031854.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 606bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-11-25
Organism	Homo sapiens(human)
Product	keratin-associated protein 4-12
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff in collaboration with Michael Rogers. The reference sequence was derived from AJ406943.1. On Oct 14, 2001 this sequence version replaced NM_031854.1. ##Evidence-Data-START## Transcript is intronless :: AJ406943.1 [ECO:0000345] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGTCAACT CCTGTTGTGG CTCTGTGTGC TCTGACCAGG GCTGTGGCCT GGAGAACTGC 
TGCCGCCCCA GCTGCTGCCA GACCACCTGC TGCAGGACCA CCTGCTGCCG CCCCAGCTGC 
TGTGTGTCCA GCTGCTGCAG GCCCCAGTGC TGCCAGTCTG TGTGCTGTCA GCCCACCTGC 
TGCCGCCCCA GCTGCTGTCA GACCACCTGC TGTAGGACCA CCTGCTGCCG CCCCAGCTGC 
TGTGTGTCCA GCTGCTGCAG ACCCCAGTGC TGCCAGTCTG TGTGCTGCCA GCCCACCTGC 
TGCCGCCCCA GCTGCTGTCA GACCACCTGC TGCAGGACCA CTTGCTGCCG CCCCAGCTGC 
TGTGTGTCCA GCTGCTGCAG ACCCCAGTGC TGCCAGTCTG TGTGCTGCCA GCCCACCTGC 
TGCCGCCCCA GCTGCTGCAT CTCCAGCAGC TGCTGCCCCT CTTGCTGTGA ATCCAGCTGC 
TGCCGCCCCT GCTGCTGCCT GCGTCCAGTC TGTGGCCGAG TCTCCTGCCA CACCACTTGC 
TATCGCCCAA CCTGTGTCAT CTCCACCTGC CCCCGCCCCT TGTGCTGTGC CTCCTCTTGC 
TGCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_114060.1
CDS	46..651
Translation	MVNSCCGSVCSDQGCGLENCCRPSCCQTTCCRTTCCRPSCCVSSCCRPQCCQSVCCQPTCCRPSCCQTTCCRTTCCRPSCCVSSCCRPQCCQSVCCQPTCCRPSCCQTTCCRTTCCRPSCCVSSCCRPQCCQSVCCQPTCCRPSCCISSSCCPSCCESSCCRPCCCLRPVCGRVSCHTTCYRPTCVISTCPRPLCCASSCC

Target ORF information:

RefSeq Version	NM_031854.2
Organism	Homo sapiens(human)
Definition	Homo sapiens keratin associated protein 4-12 (KRTAP4-12), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_031854.2

ORF Insert Sequence:

ATGGTCAACT CCTGTTGTGG CTCTGTGTGC TCTGACCAGG GCTGTGGCCT GGAGAACTGC 
TGCCGCCCCA GCTGCTGCCA GACCACCTGC TGCAGGACCA CCTGCTGCCG CCCCAGCTGC 
TGTGTGTCCA GCTGCTGCAG GCCCCAGTGC TGCCAGTCTG TGTGCTGTCA GCCCACCTGC 
TGCCGCCCCA GCTGCTGTCA GACCACCTGC TGTAGGACCA CCTGCTGCCG CCCCAGCTGC 
TGTGTGTCCA GCTGCTGCAG ACCCCAGTGC TGCCAGTCTG TGTGCTGCCA GCCCACCTGC 
TGCCGCCCCA GCTGCTGTCA GACCACCTGC TGCAGGACCA CTTGCTGCCG CCCCAGCTGC 
TGTGTGTCCA GCTGCTGCAG ACCCCAGTGC TGCCAGTCTG TGTGCTGCCA GCCCACCTGC 
TGCCGCCCCA GCTGCTGCAT CTCCAGCAGC TGCTGCCCCT CTTGCTGTGA ATCCAGCTGC 
TGCCGCCCCT GCTGCTGCCT GCGTCCAGTC TGTGGCCGAG TCTCCTGCCA CACCACTTGC 
TATCGCCCAA CCTGTGTCAT CTCCACCTGC CCCCGCCCCT TGTGCTGTGC CTCCTCTTGC 
TGCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

KRTAP4-12 ( NM_031854.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_114060.1 Homo sapiens keratin associated protein 4-12 (KRTAP4-12), mRNA.

Price & Availability↑

CloneID	OHu29331
Clone ID Related Accession (Same CDS sequence)	NM_031854.2 , NM_031854.3
Accession Version	NM_031854.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 606bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-05-01
Organism	Homo sapiens(human)
Product	keratin-associated protein 4-12
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff in collaboration with Michael Rogers. The reference sequence was derived from AC100808.10. On Nov 26, 2018 this sequence version replaced NM_031854.2. ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000394014.2/ ENSP00000377582.1 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGTCAACT CCTGTTGTGG CTCTGTGTGC TCTGACCAGG GCTGTGGCCT GGAGAACTGC 
TGCCGCCCCA GCTGCTGCCA GACCACCTGC TGCAGGACCA CCTGCTGCCG CCCCAGCTGC 
TGTGTGTCCA GCTGCTGCAG GCCCCAGTGC TGCCAGTCTG TGTGCTGTCA GCCCACCTGC 
TGCCGCCCCA GCTGCTGTCA GACCACCTGC TGTAGGACCA CCTGCTGCCG CCCCAGCTGC 
TGTGTGTCCA GCTGCTGCAG ACCCCAGTGC TGCCAGTCTG TGTGCTGCCA GCCCACCTGC 
TGCCGCCCCA GCTGCTGTCA GACCACCTGC TGCAGGACCA CTTGCTGCCG CCCCAGCTGC 
TGTGTGTCCA GCTGCTGCAG ACCCCAGTGC TGCCAGTCTG TGTGCTGCCA GCCCACCTGC 
TGCCGCCCCA GCTGCTGCAT CTCCAGCAGC TGCTGCCCCT CTTGCTGTGA ATCCAGCTGC 
TGCCGCCCCT GCTGCTGCCT GCGTCCAGTC TGTGGCCGAG TCTCCTGCCA CACCACTTGC 
TATCGCCCAA CCTGTGTCAT CTCCACCTGC CCCCGCCCCT TGTGCTGTGC CTCCTCTTGC 
TGCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_114060.1
CDS	61..666
Translation	MVNSCCGSVCSDQGCGLENCCRPSCCQTTCCRTTCCRPSCCVSSCCRPQCCQSVCCQPTCCRPSCCQTTCCRTTCCRPSCCVSSCCRPQCCQSVCCQPTCCRPSCCQTTCCRTTCCRPSCCVSSCCRPQCCQSVCCQPTCCRPSCCISSSCCPSCCESSCCRPCCCLRPVCGRVSCHTTCYRPTCVISTCPRPLCCASSCC

Target ORF information:

RefSeq Version	NM_031854.3
Organism	Homo sapiens(human)
Definition	Homo sapiens keratin associated protein 4-12 (KRTAP4-12), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_031854.3

ORF Insert Sequence:

ATGGTCAACT CCTGTTGTGG CTCTGTGTGC TCTGACCAGG GCTGTGGCCT GGAGAACTGC 
TGCCGCCCCA GCTGCTGCCA GACCACCTGC TGCAGGACCA CCTGCTGCCG CCCCAGCTGC 
TGTGTGTCCA GCTGCTGCAG GCCCCAGTGC TGCCAGTCTG TGTGCTGTCA GCCCACCTGC 
TGCCGCCCCA GCTGCTGTCA GACCACCTGC TGTAGGACCA CCTGCTGCCG CCCCAGCTGC 
TGTGTGTCCA GCTGCTGCAG ACCCCAGTGC TGCCAGTCTG TGTGCTGCCA GCCCACCTGC 
TGCCGCCCCA GCTGCTGTCA GACCACCTGC TGCAGGACCA CTTGCTGCCG CCCCAGCTGC 
TGTGTGTCCA GCTGCTGCAG ACCCCAGTGC TGCCAGTCTG TGTGCTGCCA GCCCACCTGC 
TGCCGCCCCA GCTGCTGCAT CTCCAGCAGC TGCTGCCCCT CTTGCTGTGA ATCCAGCTGC 
TGCCGCCCCT GCTGCTGCCT GCGTCCAGTC TGTGGCCGAG TCTCCTGCCA CACCACTTGC 
TATCGCCCAA CCTGTGTCAT CTCCACCTGC CCCCGCCCCT TGTGCTGTGC CTCCTCTTGC 
TGCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

An inter-species protein-protein interaction network across vast evolutionary distance.
Molecular systems biology12(4)865(2016 Apr)
Zhong Q,Pevzner SJ,Hao T,Wang Y,Mosca R,Menche J,Taipale M,Ta?an M,Fan C,Yang X,Haley P,Murray RR,Mer F,Gebreab F,Tam S,MacWilliams A,Dricot A,Reichert P,Santhanam B,Ghamsari L,Calderwood MA,Rolland T,Charloteaux B,Lindquist S,Barab?si AL,Hill DE,Aloy P,Cusick ME,Xia Y,Roth FP,Vidal M

Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing.
Cell164(4)805-17(2016 Feb)
Yang X,Coulombe-Huntington J,Kang S,Sheynkman GM,Hao T,Richardson A,Sun S,Yang F,Shen YA,Murray RR,Spirohn K,Begg BE,Duran-Frigola M,MacWilliams A,Pevzner SJ,Zhong Q,Trigg SA,Tam S,Ghamsari L,Sahni N,Yi S,Rodriguez MD,Balcha D,Tan G,Costanzo M,Andrews B,Boone C,Zhou XJ,Salehi-Ashtiani K,Charloteaux B,Chen AA,Calderwood MA,Aloy P,Roth FP,Hill DE,Iakoucheva LM,Xia Y,Vidal M

Protein interactions of the transcription factor Hoxa1.
BMC developmental biology1229(2012 Oct)
Lambert B,Vandeputte J,Remacle S,Bergiers I,Simonis N,Twizere JC,Vidal M,Rezsohazy R

A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration.
Cell125(4)801-14(2006 May)
Lim J,Hao T,Shaw C,Patel AJ,Szab? G,Rual JF,Fisk CJ,Li N,Smolyar A,Hill DE,Barab?si AL,Vidal M,Zoghbi HY

Characterization of a cluster of human high/ultrahigh sulfur keratin-associated protein genes embedded in the type I keratin gene domain on chromosome 17q12-21.
The Journal of biological chemistry276(22)19440-51(2001 Jun)
Rogers MA,Langbein L,Winter H,Ehmann C,Praetzel S,Korn B,Schweizer J

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KRTAP4-12 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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