HIST1H4G cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	HIST1H4G
Entrez Gene ID	8369
Full Name	histone cluster 1 H4 family member g
Synonyms	H4/l,H4FL
General protein information	Preferred Names histone cluster 1 H4 family member g Names histone H4-like protein type G H4 histone family, member L histone 1, H4g histone cluster 1, H4g
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 6 Map Location: 6p22.2
Summary	Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H4 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6. [provided by RefSeq, Aug 2015].
Disorder MIM:	602832

mRNA and Protein(s)

mRNA	Protein	Name
NM_003547.3	NP_003538.1	histone H4-like protein type G
NM_003547.2	NP_003538.1	histone H4-like protein type G

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	LOC472229	XP_527603.1
Homo sapiens (human)	HIST1H4G	NP_003538.1

Gene Ontology
Bibliography

Related articles in PubMed

Proteomic characterization of the human sperm nucleus.
de Mateo S, Castillo J, Estanyol JM, Ballesc? JL, Oliva R
Proteomics11(13)2714-26(2011 Jul)

Regulation of HIV-1 gene expression by histone acetylation and factor recruitment at the LTR promoter.
Lusic M, Marcello A, Cereseto A, Giacca M
The EMBO journal22(24)6550-61(2003 Dec)

The human and mouse replication-dependent histone genes.
Marzluff WF, Gongidi P, Woods KR, Jin J, Maltais LJ
Genomics80(5)487-98(2002 Nov)

Enhancement of the p300 HAT activity by HIV-1 Tat on chromatin DNA.
Deng L, Wang D, de la Fuente C, Wang L, Li H, Lee CG, Donnelly R, Wade JD, Lambert P, Kashanchi F
Virology289(2)312-26(2001 Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following HIST1H4G gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the HIST1H4G cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu30021	NM_003547.3 Latest version!	Homo sapiens H4 clustered histone 7 (H4C7), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
View Old Accession Versions >>
OHu30021	NM_003547.2	Homo sapiens histone cluster 1 H4 family member g (HIST1H4G), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
Hide Old Accession Versions >>

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

HIST1H4G ( NM_003547.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_003538.1 Homo sapiens H4 clustered histone 7 (H4C7), mRNA.

Price & Availability↑

CloneID	OHu30021
Clone ID Related Accession (Same CDS sequence)	NM_003547.3 , NM_003547.2
Accession Version	NM_003547.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 297bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-19
Organism	Homo sapiens(human)
Product	histone H4-like protein type G
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AL031777.5. On Dec 3, 2019 this sequence version replaced NM_003547.2. ##Evidence-Data-START## Transcript is intronless :: BC126276.1 [ECO:0000345] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on single protein-coding transcript replication-dependent histone :: PMID: 12408966 ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGTCTGTTC GGGGCAAGGC CGGAAAAGGC CTTGGGAAAG GCGGTGCCAA GTGCCATCGC 
AAGGTACTGA GCGATAATAT TCAGGGCATT ACCAAGTGCA CTATCCGGCG CTTGGCCCGG 
CATGGCGGTG TCAAGCGCAT CTTGGGCCTC ATTTATGAGG AGACCCGCCG GGTGTTCAAG 
GTGTTCCTGG AAAATGTGAT CTGGTACGCC GTGACCAACA CGGAGCACGC CAAGCGCAAG 
ACGGTCACCG CCATGGCCGT GGTCTACGTG CTCAAACGCC AGGGAAGAAC CCTGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_003538.1
CDS	20..316
Translation	MSVRGKAGKGLGKGGAKCHRKVLSDNIQGITKCTIRRLARHGGVKRILGLIYEETRRVFKVFLENVIWYAVTNTEHAKRKTVTAMAVVYVLKRQGRTL

Target ORF information:

RefSeq Version	NM_003547.3
Organism	Homo sapiens(human)
Definition	Homo sapiens H4 clustered histone 7 (H4C7), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_003547.3

ORF Insert Sequence:

ATGTCTGTTC GGGGCAAGGC CGGAAAAGGC CTTGGGAAAG GCGGTGCCAA GTGCCATCGC 
AAGGTACTGA GCGATAATAT TCAGGGCATT ACCAAGTGCA CTATCCGGCG CTTGGCCCGG 
CATGGCGGTG TCAAGCGCAT CTTGGGCCTC ATTTATGAGG AGACCCGCCG GGTGTTCAAG 
GTGTTCCTGG AAAATGTGAT CTGGTACGCC GTGACCAACA CGGAGCACGC CAAGCGCAAG 
ACGGTCACCG CCATGGCCGT GGTCTACGTG CTCAAACGCC AGGGAAGAAC CCTGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

HIST1H4G ( NM_003547.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_003538.1 Homo sapiens histone cluster 1 H4 family member g (HIST1H4G), mRNA.

Price & Availability↑

CloneID	OHu30021
Clone ID Related Accession (Same CDS sequence)	NM_003547.3 , NM_003547.2
Accession Version	NM_003547.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 297bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-05-03
Organism	Homo sapiens(human)
Product	histone H4-like protein type G
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from Z80788.1. On May 24, 2002 this sequence version replaced NM_003547.1. ##RefSeq-Attributes-START## RefSeq Select criteria :: based on single protein-coding transcript replication-dependent histone :: PMID: 12408966 ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGTCTGTTC GGGGCAAGGC CGGAAAAGGC CTTGGGAAAG GCGGTGCCAA GTGCCATCGC 
AAGGTACTGA GCGATAATAT TCAGGGCATT ACCAAGTGCA CTATCCGGCG CTTGGCCCGG 
CATGGCGGTG TCAAGCGCAT CTTGGGCCTC ATTTATGAGG AGACCCGCCG GGTGTTCAAG 
GTGTTCCTGG AAAATGTGAT CTGGTACGCC GTGACCAACA CGGAGCACGC CAAGCGCAAG 
ACGGTCACCG CCATGGCCGT GGTCTACGTG CTCAAACGCC AGGGAAGAAC CCTGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_003538.1
CDS	1..297
Translation	MSVRGKAGKGLGKGGAKCHRKVLSDNIQGITKCTIRRLARHGGVKRILGLIYEETRRVFKVFLENVIWYAVTNTEHAKRKTVTAMAVVYVLKRQGRTL

Target ORF information:

RefSeq Version	NM_003547.2
Organism	Homo sapiens(human)
Definition	Homo sapiens histone cluster 1 H4 family member g (HIST1H4G), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_003547.2

ORF Insert Sequence:

ATGTCTGTTC GGGGCAAGGC CGGAAAAGGC CTTGGGAAAG GCGGTGCCAA GTGCCATCGC 
AAGGTACTGA GCGATAATAT TCAGGGCATT ACCAAGTGCA CTATCCGGCG CTTGGCCCGG 
CATGGCGGTG TCAAGCGCAT CTTGGGCCTC ATTTATGAGG AGACCCGCCG GGTGTTCAAG 
GTGTTCCTGG AAAATGTGAT CTGGTACGCC GTGACCAACA CGGAGCACGC CAAGCGCAAG 
ACGGTCACCG CCATGGCCGT GGTCTACGTG CTCAAACGCC AGGGAAGAAC CCTGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Proteomic characterization of the human sperm nucleus.
Proteomics11(13)2714-26(2011 Jul)
de Mateo S,Castillo J,Estanyol JM,Ballesc? JL,Oliva R

Regulation of HIV-1 gene expression by histone acetylation and factor recruitment at the LTR promoter.
The EMBO journal22(24)6550-61(2003 Dec)
Lusic M,Marcello A,Cereseto A,Giacca M

The human and mouse replication-dependent histone genes.
Genomics80(5)487-98(2002 Nov)
Marzluff WF,Gongidi P,Woods KR,Jin J,Maltais LJ

Enhancement of the p300 HAT activity by HIV-1 Tat on chromatin DNA.
Virology289(2)312-26(2001 Oct)
Deng L,Wang D,de la Fuente C,Wang L,Li H,Lee CG,Donnelly R,Wade JD,Lambert P,Kashanchi F

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HIST1H4G cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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