UCK1 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	UCK1
Entrez Gene ID	83549
Full Name	uridine-cytidine kinase 1
Synonyms	URK1
General protein information	Preferred Names uridine-cytidine kinase 1 Names uridine-cytidine kinase 1 cytidine monophosphokinase 1 uridine monophosphokinase 1
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 9 Map Location: 9q34.13
Summary	This gene encodes a uridine-cytidine kinase that catalyzes the phosphorylation of uridine and cytidine to uridine monophosphate (UMP) and cytidine monophosphate (CMP) but not the phosphorylation of deoxyribonucleosides or purine ribonucleosides. This enzyme can also phosphorylate uridine and cytidine analogs and uses both ATP and GTP as a phosphate donor. Alternative splicing results in multiple splice variants encoding distinct isoforms. [provided by RefSeq, May 2012].
Disorder MIM:	609328

mRNA and Protein(s)

mRNA	Protein	Name
NM_001261451.2	NP_001248380.1	uridine-cytidine kinase 1 isoform d
NM_031432.5	NP_113620.1	uridine-cytidine kinase 1 isoform a
NM_031432.4	NP_113620.1	uridine-cytidine kinase 1 isoform a
NM_001135954.2	NP_001129426.1	uridine-cytidine kinase 1 isoform b
XM_005272224.2	XP_005272281.1	uridine-cytidine kinase 1 isoform X1
NM_031432.3	NP_113620.1	uridine-cytidine kinase 1 isoform a
NM_001261450.2	NP_001248379.1	uridine-cytidine kinase 1 isoform c
NM_001318519.1	NP_001305448.1	uridine-cytidine kinase 1 isoform e

Pathways from BioSystems

Homologies

	UCK1	XP_001105895.1
Bos taurus (cattle)	UCK1	NP_001069260.1
Mus musculus (house mouse)	Uck1	NP_035805.2
Danio rerio (zebrafish)	uck1	NP_001004666.1
Homo sapiens (human)	UCK1	NP_113620.1
Canis lupus familiaris (dog)	UCK1	XP_005625497.1
Rattus norvegicus (Norway rat)	Uck1	NP_001101301.2
Xenopus tropicalis (tropical clawed frog)	LOC100491950	XP_002936235.2
Gallus gallus (chicken)	UCK1	XP_004945954.1

Gene Ontology
Bibliography

Related articles in PubMed

Purification, activity, and expression levels of two uridine-cytidine kinase isoforms in neuroblastoma cell lines.
Meinsma R, van Kuilenburg AB
Nucleosides, nucleotides & nucleic acids35(10-12)613-618(2016 Dec)

The pivotal role of uridine-cytidine kinases in pyrimidine metabolism and activation of cytotoxic nucleoside analogues in neuroblastoma.
van Kuilenburg AB, Meinsma R
Biochimica et biophysica acta1862(9)1504-12(2016 Sep)

Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing.
Yang X, Coulombe-Huntington J, Kang S, Sheynkman GM, Hao T, Richardson A, Sun S, Yang F, Shen YA, Murray RR, Spirohn K, Begg BE, Duran-Frigola M, MacWilliams A, Pevzner SJ, Zhong Q, Trigg SA, Tam S, Ghamsari L, Sahni N, Yi S, Rodriguez MD, Balcha D, Tan G, Costanzo M, Andrews B, Boone C, Zhou XJ, Salehi-Ashtiani K, Charloteaux B, Chen AA, Calderwood MA, Aloy P, Roth FP, Hill DE, Iakoucheva LM, Xia Y, Vidal M
Cell164(4)805-17(2016 Feb)

Variability of Gene Expression Identifies Transcriptional Regulators of Early Human Embryonic Development.
Hasegawa Y, Taylor D, Ovchinnikov DA, Wolvetang EJ, de Torrent? L, Mar JC
PLoS genetics11(8)e1005428(2015 Aug)

Expression of nucleoside-metabolizing enzymes in myelodysplastic syndromes and modulation of response to azacitidine.
Valencia A, Masala E, Rossi A, Martino A, Sanna A, Buchi F, Canzian F, Cilloni D, Gaidano V, Voso MT, Kosmider O, Fontenay M, Gozzini A, Bosi A, Santini V
Leukemia28(3)621-8(2014 Mar)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

UCK1 and 2 are both expressed in several neuroblastoma cell lines, including four MYCN single copy cell lines and five MYCN amplified cell lines
Title: Purification, activity, and expression levels of two uridine-cytidine kinase isoforms in neuroblastoma cell lines.

ribavirin is a potential substrate of UCK-1, and RMP formed could be chemically coupled to AsOR to form a conjugate for liver specific targeting.
Title: Human uridine-cytidine kinase phosphorylation of ribavirin: a convenient method for activation of ribavirin for conjugation to proteins.

The following UCK1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the UCK1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu15034	NM_001261451.2 Latest version!	Homo sapiens uridine-cytidine kinase 1 (UCK1), transcript variant 4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$99.50-$139.30 $199.00
OHu15101	NM_001261450.2 Latest version!	Homo sapiens uridine-cytidine kinase 1 (UCK1), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
OHu15324	NM_001135954.2 Latest version!	Homo sapiens uridine-cytidine kinase 1 (UCK1), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$188.30 $269.00
OHu43535	NM_001318519.1 Latest version!	Homo sapiens uridine-cytidine kinase 1 (UCK1), transcript variant 5, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
OHu43534	XM_005272224.2 Latest version!	Homo sapiens uridine-cytidine kinase 1 (UCK1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
OHu15333	NM_031432.5 Latest version!	Homo sapiens uridine-cytidine kinase 1 (UCK1), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
View Old Accession Versions >>
OHu15333	NM_031432.4	Homo sapiens uridine-cytidine kinase 1 (UCK1), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$216.30 $309.00
OHu15333	NM_031432.3	Homo sapiens uridine-cytidine kinase 1 (UCK1), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$216.30 $309.00
Hide Old Accession Versions >>

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***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

UCK1 ( NM_001261451.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001248380.1 Homo sapiens uridine-cytidine kinase 1 (UCK1), transcript variant 4, mRNA.

Price & Availability↑

CloneID	OHu15034
Clone ID Related Accession (Same CDS sequence)	NM_001261451.2
Accession Version	NM_001261451.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 849bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-04
Organism	Homo sapiens(human)
Product	uridine-cytidine kinase 1 isoform d
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA598285.1, BI770572.1, AL358781.19, AK022317.1 and AA809511.1. On Jan 8, 2016 this sequence version replaced NM_001261451.1. Transcript Variant: This variant (4) has multiple differences in the 5' coding region, compared to variant 1, that result in a protein (isoform d) with a longer N-terminus, compared to isoform a. ##Evidence-Data-START## Transcript exon combination :: BI770572.1, BI770639.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCTTCGG CGGGAGGCGA AGACTGCGAG AGCCCCGCGC CGGAGGCCGA CCGTCCGCAC 
CAGCGGCCCT TCCTGATAGG GGACGAGCGG TTCCAGGCGG GAATCCCGCT TCTGTGTCTC 
CAGTCGACCG TGTGTGAGAA GATCATGGAG TTGCTGGGAC AGAACGAGGT GGAACAGCGG 
CAGCGGAAGG TGGTCATCCT GAGCCAGGAC AGGTTCTACA AGGTCCTGAC GGCAGAGCAG 
AAGGCCAAGG CCTTGAAAGG ACAGTACAAT TTTGACCATC CAGATGCCTT TGATAATGAT 
TTGATGCACA GGACTCTGAA GAACATCGTG GAGGGCAAAA CGGTGGAGGT GCCGACCTAT 
GATTTTGTGA CACACTCAAG GTTACCAGAG ACCACGGTGG TCTACCCTGC GGACGTGGTT 
CTGTTTGAGG GCATCTTGGT GTTCTACAGC CAGGAGATCC GGGACATGTT CCACCTGCGC 
CTCTTCGTGG ACACCGACTC CGACGTCAGG CTGTCTCGAA GAGTTCTCCG GGACGTGCGC 
CGAGGGAGGG ACCTGGAGCA GATTCTGACG CAGTACACCA CCTTCGTGAA GCCGGCCTTC 
GAGGAGTTCT GCCTGCCGAC AAAGAAGTAT GCCGATGTGA TCATCCCGCG AGGAGTGGAC 
AATATGGTTG CCATCAACCT GATCGTGCAG CACATCCAGG ACATTCTGAA TGGTGACATC 
TGCAAATGGC ACCGAGGAGG GTCCAATGGG CGGAGCTACA AGCGGACCTT TTCTGAGCCA 
GGGGACCACC CTGGGATGCT GACCTCTGGC AAACGGTCAC ATTTGGAGTC CAGCAGCAGA 
CCCCACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001248380.1
CDS	102..950
Translation	MASAGGEDCESPAPEADRPHQRPFLIGDERFQAGIPLLCLQSTVCEKIMELLGQNEVEQRQRKVVILSQDRFYKVLTAEQKAKALKGQYNFDHPDAFDNDLMHRTLKNIVEGKTVEVPTYDFVTHSRLPETTVVYPADVVLFEGILVFYSQEIRDMFHLRLFVDTDSDVRLSRRVLRDVRRGRDLEQILTQYTTFVKPAFEEFCLPTKKYADVIIPRGVDNMVAINLIVQHIQDILNGDICKWHRGGSNGRSYKRTFSEPGDHPGMLTSGKRSHLESSSRPH

Target ORF information:

RefSeq Version	NM_001261451.2
Organism	Homo sapiens(human)
Definition	Homo sapiens uridine-cytidine kinase 1 (UCK1), transcript variant 4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001261451.2

ORF Insert Sequence:

ATGGCTTCGG CGGGAGGCGA AGACTGCGAG AGCCCCGCGC CGGAGGCCGA CCGTCCGCAC 
CAGCGGCCCT TCCTGATAGG GGACGAGCGG TTCCAGGCGG GAATCCCGCT TCTGTGTCTC 
CAGTCGACCG TGTGTGAGAA GATCATGGAG TTGCTGGGAC AGAACGAGGT GGAACAGCGG 
CAGCGGAAGG TGGTCATCCT GAGCCAGGAC AGGTTCTACA AGGTCCTGAC GGCAGAGCAG 
AAGGCCAAGG CCTTGAAAGG ACAGTACAAT TTTGACCATC CAGATGCCTT TGATAATGAT 
TTGATGCACA GGACTCTGAA GAACATCGTG GAGGGCAAAA CGGTGGAGGT GCCGACCTAT 
GATTTTGTGA CACACTCAAG GTTACCAGAG ACCACGGTGG TCTACCCTGC GGACGTGGTT 
CTGTTTGAGG GCATCTTGGT GTTCTACAGC CAGGAGATCC GGGACATGTT CCACCTGCGC 
CTCTTCGTGG ACACCGACTC CGACGTCAGG CTGTCTCGAA GAGTTCTCCG GGACGTGCGC 
CGAGGGAGGG ACCTGGAGCA GATTCTGACG CAGTACACCA CCTTCGTGAA GCCGGCCTTC 
GAGGAGTTCT GCCTGCCGAC AAAGAAGTAT GCCGATGTGA TCATCCCGCG AGGAGTGGAC 
AATATGGTTG CCATCAACCT GATCGTGCAG CACATCCAGG ACATTCTGAA TGGTGACATC 
TGCAAATGGC ACCGAGGAGG GTCCAATGGG CGGAGCTACA AGCGGACCTT TTCTGAGCCA 
GGGGACCACC CTGGGATGCT GACCTCTGGC AAACGGTCAC ATTTGGAGTC CAGCAGCAGA 
CCCCACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

UCK1 ( NM_001261450.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001248379.1 Homo sapiens uridine-cytidine kinase 1 (UCK1), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu15101
Clone ID Related Accession (Same CDS sequence)	NM_001261450.2
Accession Version	NM_001261450.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 807bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-05
Organism	Homo sapiens(human)
Product	uridine-cytidine kinase 1 isoform c
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA598285.1, AK307475.1, AL358781.19, AK022317.1 and AA809511.1. On Jan 8, 2016 this sequence version replaced NM_001261450.1. Transcript Variant: This variant (3) uses an alternate splice site in the 5' coding region, compared to variant 1, that results in a protein (isoform c) with a shorter N-terminus, compared to isoform c. ##Evidence-Data-START## Transcript exon combination :: SRR1163657.262829.1, SRR1803612.61642.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCTTCGG CGGGAGGCGA AGACTGCGAG AGCCCCGCGC CGGAGGCCGA CCGTCCGCAC 
CAGCGGCCCT TCCTGATAGG GTCGACCGTG TGTGAGAAGA TCATGGAGTT GCTGGGACAG 
AACGAGGTGG AACAGCGGCA GCGGAAGGTG GTCATCCTGA GCCAGGACAG GTTCTACAAG 
GTCCTGACGG CAGAGCAGAA GGCCAAGGCC TTGAAAGGAC AGTACAATTT TGACCATCCA 
GATGCCTTTG ATAATGATTT GATGCACAGG ACTCTGAAGA ACATCGTGGA GGGCAAAACG 
GTGGAGGTGC CGACCTATGA TTTTGTGACA CACTCAAGGT TACCAGAGAC CACGGTGGTC 
TACCCTGCGG ACGTGGTTCT GTTTGAGGGC ATCTTGGTGT TCTACAGCCA GGAGATCCGG 
GACATGTTCC ACCTGCGCCT CTTCGTGGAC ACCGACTCCG ACGTCAGGCT GTCTCGAAGA 
GTTCTCCGGG ACGTGCGCCG AGGGAGGGAC CTGGAGCAGA TTCTGACGCA GTACACCACC 
TTCGTGAAGC CGGCCTTCGA GGAGTTCTGC CTGCCGACAA AGAAGTATGC CGATGTGATC 
ATCCCGCGAG GAGTGGACAA TATGGTTGCC ATCAACCTGA TCGTGCAGCA CATCCAGGAC 
ATTCTGAATG GTGACATCTG CAAATGGCAC CGAGGAGGGT CCAATGGGCG GAGCTACAAG 
CGGACCTTTT CTGAGCCAGG GGACCACCCT GGGATGCTGA CCTCTGGCAA ACGGTCACAT 
TTGGAGTCCA GCAGCAGACC CCACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001248379.1
CDS	102..908
Translation	MASAGGEDCESPAPEADRPHQRPFLIGSTVCEKIMELLGQNEVEQRQRKVVILSQDRFYKVLTAEQKAKALKGQYNFDHPDAFDNDLMHRTLKNIVEGKTVEVPTYDFVTHSRLPETTVVYPADVVLFEGILVFYSQEIRDMFHLRLFVDTDSDVRLSRRVLRDVRRGRDLEQILTQYTTFVKPAFEEFCLPTKKYADVIIPRGVDNMVAINLIVQHIQDILNGDICKWHRGGSNGRSYKRTFSEPGDHPGMLTSGKRSHLESSSRPH

Target ORF information:

RefSeq Version	NM_001261450.2
Organism	Homo sapiens(human)
Definition	Homo sapiens uridine-cytidine kinase 1 (UCK1), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001261450.2

ORF Insert Sequence:

ATGGCTTCGG CGGGAGGCGA AGACTGCGAG AGCCCCGCGC CGGAGGCCGA CCGTCCGCAC 
CAGCGGCCCT TCCTGATAGG GTCGACCGTG TGTGAGAAGA TCATGGAGTT GCTGGGACAG 
AACGAGGTGG AACAGCGGCA GCGGAAGGTG GTCATCCTGA GCCAGGACAG GTTCTACAAG 
GTCCTGACGG CAGAGCAGAA GGCCAAGGCC TTGAAAGGAC AGTACAATTT TGACCATCCA 
GATGCCTTTG ATAATGATTT GATGCACAGG ACTCTGAAGA ACATCGTGGA GGGCAAAACG 
GTGGAGGTGC CGACCTATGA TTTTGTGACA CACTCAAGGT TACCAGAGAC CACGGTGGTC 
TACCCTGCGG ACGTGGTTCT GTTTGAGGGC ATCTTGGTGT TCTACAGCCA GGAGATCCGG 
GACATGTTCC ACCTGCGCCT CTTCGTGGAC ACCGACTCCG ACGTCAGGCT GTCTCGAAGA 
GTTCTCCGGG ACGTGCGCCG AGGGAGGGAC CTGGAGCAGA TTCTGACGCA GTACACCACC 
TTCGTGAAGC CGGCCTTCGA GGAGTTCTGC CTGCCGACAA AGAAGTATGC CGATGTGATC 
ATCCCGCGAG GAGTGGACAA TATGGTTGCC ATCAACCTGA TCGTGCAGCA CATCCAGGAC 
ATTCTGAATG GTGACATCTG CAAATGGCAC CGAGGAGGGT CCAATGGGCG GAGCTACAAG 
CGGACCTTTT CTGAGCCAGG GGACCACCCT GGGATGCTGA CCTCTGGCAA ACGGTCACAT 
TTGGAGTCCA GCAGCAGACC CCACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

UCK1 ( NM_001135954.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001129426.1 Homo sapiens uridine-cytidine kinase 1 (UCK1), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu15324
Clone ID Related Accession (Same CDS sequence)	NM_001135954.2
Accession Version	NM_001135954.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 606bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-04
Organism	Homo sapiens(human)
Product	uridine-cytidine kinase 1 isoform b
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA598285.1, BC015547.1, AL358781.19 and AA809511.1. On Jan 8, 2016 this sequence version replaced NM_001135954.1. Transcript Variant: This variant (2) lacks an exon in the 3' coding region which results in a frameshift and an early stop codon, compared to variant 1. This variant encodes isoform b which has a shorter and distinct C-terminus, compared to isoform a. ##Evidence-Data-START## Transcript exon combination :: BC015547.1, SRR1660809.232525.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCTTCGG CGGGAGGCGA AGACTGCGAG AGCCCCGCGC CGGAGGCCGA CCGTCCGCAC 
CAGCGGCCCT TCCTGATAGG GGTGAGCGGC GGCACTGCCA GCGGGAAGTC GACCGTGTGT 
GAGAAGATCA TGGAGTTGCT GGGACAGAAC GAGGTGGAAC AGCGGCAGCG GAAGGTGGTC 
ATCCTGAGCC AGGACAGGTT CTACAAGGTC CTGACGGCAG AGCAGAAGGC CAAGGCCTTG 
AAAGGACAGT ACAATTTTGA CCATCCAGAT GCCTTTGATA ATGATTTGAT GCACAGGACT 
CTGAAGAACA TCGTGGAGGG CAAAACGGTG GAGGTGCCGA CCTATGATTT TGTGACACAC 
TCAAGGTTAC CAGAGACCAC GGTGGTCTAC CCTGCGGACG TGGTTCTGTT TGAGGGCATC 
TTGGTGTTCT ACAGCCAGGA GATCCGGGAC ATGTTCCACC TGCGCCTCTT CGTGGACACC 
GACTCCGACG TCAGGCTGTC TCGAAGAGAC AAAGAAGTAT GCCGATGTGA TCATCCCGCG 
AGGAGTGGAC AATATGGTTG CCATCAACCT GATCGTGCAG CACATCCAGG ACATTCTGAA 
TGGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001129426.1
CDS	102..707
Translation	MASAGGEDCESPAPEADRPHQRPFLIGVSGGTASGKSTVCEKIMELLGQNEVEQRQRKVVILSQDRFYKVLTAEQKAKALKGQYNFDHPDAFDNDLMHRTLKNIVEGKTVEVPTYDFVTHSRLPETTVVYPADVVLFEGILVFYSQEIRDMFHLRLFVDTDSDVRLSRRDKEVCRCDHPARSGQYGCHQPDRAAHPGHSEW

Target ORF information:

RefSeq Version	NM_001135954.2
Organism	Homo sapiens(human)
Definition	Homo sapiens uridine-cytidine kinase 1 (UCK1), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001135954.2

ORF Insert Sequence:

ATGGCTTCGG CGGGAGGCGA AGACTGCGAG AGCCCCGCGC CGGAGGCCGA CCGTCCGCAC 
CAGCGGCCCT TCCTGATAGG GGTGAGCGGC GGCACTGCCA GCGGGAAGTC GACCGTGTGT 
GAGAAGATCA TGGAGTTGCT GGGACAGAAC GAGGTGGAAC AGCGGCAGCG GAAGGTGGTC 
ATCCTGAGCC AGGACAGGTT CTACAAGGTC CTGACGGCAG AGCAGAAGGC CAAGGCCTTG 
AAAGGACAGT ACAATTTTGA CCATCCAGAT GCCTTTGATA ATGATTTGAT GCACAGGACT 
CTGAAGAACA TCGTGGAGGG CAAAACGGTG GAGGTGCCGA CCTATGATTT TGTGACACAC 
TCAAGGTTAC CAGAGACCAC GGTGGTCTAC CCTGCGGACG TGGTTCTGTT TGAGGGCATC 
TTGGTGTTCT ACAGCCAGGA GATCCGGGAC ATGTTCCACC TGCGCCTCTT CGTGGACACC 
GACTCCGACG TCAGGCTGTC TCGAAGAGAC AAAGAAGTAT GCCGATGTGA TCATCCCGCG 
AGGAGTGGAC AATATGGTTG CCATCAACCT GATCGTGCAG CACATCCAGG ACATTCTGAA 
TGGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

UCK1 ( NM_031432.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_113620.1 Homo sapiens uridine-cytidine kinase 1 (UCK1), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu15333
Clone ID Related Accession (Same CDS sequence)	NM_031432.5 , NM_031432.4 , NM_031432.3
Accession Version	NM_031432.4	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 834bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-06-07
Organism	Homo sapiens(human)
Product	uridine-cytidine kinase 1 isoform a
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA598285.1, AK022317.1, AL358781.19 and AA809511.1. On Nov 22, 2018 this sequence version replaced NM_031432.3. Transcript Variant: This variant (1) represents the predominant transcript and encodes the isoform a. ##Evidence-Data-START## Transcript exon combination :: SRR3476690.273013.1, AK022317.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on conservation, expression ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGCTTCGG CGGGAGGCGA AGACTGCGAG AGCCCCGCGC CGGAGGCCGA CCGTCCGCAC 
CAGCGGCCCT TCCTGATAGG GGTGAGCGGC GGCACTGCCA GCGGGAAGTC GACCGTGTGT 
GAGAAGATCA TGGAGTTGCT GGGACAGAAC GAGGTGGAAC AGCGGCAGCG GAAGGTGGTC 
ATCCTGAGCC AGGACAGGTT CTACAAGGTC CTGACGGCAG AGCAGAAGGC CAAGGCCTTG 
AAAGGACAGT ACAATTTTGA CCATCCAGAT GCCTTTGATA ATGATTTGAT GCACAGGACT 
CTGAAGAACA TCGTGGAGGG CAAAACGGTG GAGGTGCCGA CCTATGATTT TGTGACACAC 
TCAAGGTTAC CAGAGACCAC GGTGGTCTAC CCTGCGGACG TGGTTCTGTT TGAGGGCATC 
TTGGTGTTCT ACAGCCAGGA GATCCGGGAC ATGTTCCACC TGCGCCTCTT CGTGGACACC 
GACTCCGACG TCAGGCTGTC TCGAAGAGTT CTCCGGGACG TGCGCCGAGG GAGGGACCTG 
GAGCAGATTC TGACGCAGTA CACCACCTTC GTGAAGCCGG CCTTCGAGGA GTTCTGCCTG 
CCGACAAAGA AGTATGCCGA TGTGATCATC CCGCGAGGAG TGGACAATAT GGTTGCCATC 
AACCTGATCG TGCAGCACAT CCAGGACATT CTGAATGGTG ACATCTGCAA ATGGCACCGA 
GGAGGGTCCA ATGGGCGGAG CTACAAGCGG ACCTTTTCTG AGCCAGGGGA CCACCCTGGG 
ATGCTGACCT CTGGCAAACG GTCACATTTG GAGTCCAGCA GCAGACCCCA CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_113620.1
CDS	90..923
Translation	MASAGGEDCESPAPEADRPHQRPFLIGVSGGTASGKSTVCEKIMELLGQNEVEQRQRKVVILSQDRFYKVLTAEQKAKALKGQYNFDHPDAFDNDLMHRTLKNIVEGKTVEVPTYDFVTHSRLPETTVVYPADVVLFEGILVFYSQEIRDMFHLRLFVDTDSDVRLSRRVLRDVRRGRDLEQILTQYTTFVKPAFEEFCLPTKKYADVIIPRGVDNMVAINLIVQHIQDILNGDICKWHRGGSNGRSYKRTFSEPGDHPGMLTSGKRSHLESSSRPH

Target ORF information:

RefSeq Version	NM_031432.4
Organism	Homo sapiens(human)
Definition	Homo sapiens uridine-cytidine kinase 1 (UCK1), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_031432.4

ORF Insert Sequence:

ATGGCTTCGG CGGGAGGCGA AGACTGCGAG AGCCCCGCGC CGGAGGCCGA CCGTCCGCAC 
CAGCGGCCCT TCCTGATAGG GGTGAGCGGC GGCACTGCCA GCGGGAAGTC GACCGTGTGT 
GAGAAGATCA TGGAGTTGCT GGGACAGAAC GAGGTGGAAC AGCGGCAGCG GAAGGTGGTC 
ATCCTGAGCC AGGACAGGTT CTACAAGGTC CTGACGGCAG AGCAGAAGGC CAAGGCCTTG 
AAAGGACAGT ACAATTTTGA CCATCCAGAT GCCTTTGATA ATGATTTGAT GCACAGGACT 
CTGAAGAACA TCGTGGAGGG CAAAACGGTG GAGGTGCCGA CCTATGATTT TGTGACACAC 
TCAAGGTTAC CAGAGACCAC GGTGGTCTAC CCTGCGGACG TGGTTCTGTT TGAGGGCATC 
TTGGTGTTCT ACAGCCAGGA GATCCGGGAC ATGTTCCACC TGCGCCTCTT CGTGGACACC 
GACTCCGACG TCAGGCTGTC TCGAAGAGTT CTCCGGGACG TGCGCCGAGG GAGGGACCTG 
GAGCAGATTC TGACGCAGTA CACCACCTTC GTGAAGCCGG CCTTCGAGGA GTTCTGCCTG 
CCGACAAAGA AGTATGCCGA TGTGATCATC CCGCGAGGAG TGGACAATAT GGTTGCCATC 
AACCTGATCG TGCAGCACAT CCAGGACATT CTGAATGGTG ACATCTGCAA ATGGCACCGA 
GGAGGGTCCA ATGGGCGGAG CTACAAGCGG ACCTTTTCTG AGCCAGGGGA CCACCCTGGG 
ATGCTGACCT CTGGCAAACG GTCACATTTG GAGTCCAGCA GCAGACCCCA CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

UCK1 ( NM_031432.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_113620.1 Homo sapiens uridine-cytidine kinase 1 (UCK1), transcript variant 1, mRNA.

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CloneID	OHu15333
Clone ID Related Accession (Same CDS sequence)	NM_031432.5 , NM_031432.4 , NM_031432.3
Accession Version	NM_031432.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 834bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-02
Organism	Homo sapiens(human)
Product	uridine-cytidine kinase 1 isoform a
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA598285.1, AK022317.1, AL358781.19 and AA809511.1. On Jan 8, 2016 this sequence version replaced NM_031432.2. Transcript Variant: This variant (1) represents the predominant transcript and encodes the isoform a. ##Evidence-Data-START## Transcript exon combination :: AK022317.1, BC091495.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCTTCGG CGGGAGGCGA AGACTGCGAG AGCCCCGCGC CGGAGGCCGA CCGTCCGCAC 
CAGCGGCCCT TCCTGATAGG GGTGAGCGGC GGCACTGCCA GCGGGAAGTC GACCGTGTGT 
GAGAAGATCA TGGAGTTGCT GGGACAGAAC GAGGTGGAAC AGCGGCAGCG GAAGGTGGTC 
ATCCTGAGCC AGGACAGGTT CTACAAGGTC CTGACGGCAG AGCAGAAGGC CAAGGCCTTG 
AAAGGACAGT ACAATTTTGA CCATCCAGAT GCCTTTGATA ATGATTTGAT GCACAGGACT 
CTGAAGAACA TCGTGGAGGG CAAAACGGTG GAGGTGCCGA CCTATGATTT TGTGACACAC 
TCAAGGTTAC CAGAGACCAC GGTGGTCTAC CCTGCGGACG TGGTTCTGTT TGAGGGCATC 
TTGGTGTTCT ACAGCCAGGA GATCCGGGAC ATGTTCCACC TGCGCCTCTT CGTGGACACC 
GACTCCGACG TCAGGCTGTC TCGAAGAGTT CTCCGGGACG TGCGCCGAGG GAGGGACCTG 
GAGCAGATTC TGACGCAGTA CACCACCTTC GTGAAGCCGG CCTTCGAGGA GTTCTGCCTG 
CCGACAAAGA AGTATGCCGA TGTGATCATC CCGCGAGGAG TGGACAATAT GGTTGCCATC 
AACCTGATCG TGCAGCACAT CCAGGACATT CTGAATGGTG ACATCTGCAA ATGGCACCGA 
GGAGGGTCCA ATGGGCGGAG CTACAAGCGG ACCTTTTCTG AGCCAGGGGA CCACCCTGGG 
ATGCTGACCT CTGGCAAACG GTCACATTTG GAGTCCAGCA GCAGACCCCA CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_113620.1
CDS	102..935
Translation	MASAGGEDCESPAPEADRPHQRPFLIGVSGGTASGKSTVCEKIMELLGQNEVEQRQRKVVILSQDRFYKVLTAEQKAKALKGQYNFDHPDAFDNDLMHRTLKNIVEGKTVEVPTYDFVTHSRLPETTVVYPADVVLFEGILVFYSQEIRDMFHLRLFVDTDSDVRLSRRVLRDVRRGRDLEQILTQYTTFVKPAFEEFCLPTKKYADVIIPRGVDNMVAINLIVQHIQDILNGDICKWHRGGSNGRSYKRTFSEPGDHPGMLTSGKRSHLESSSRPH

Target ORF information:

RefSeq Version	NM_031432.3
Organism	Homo sapiens(human)
Definition	Homo sapiens uridine-cytidine kinase 1 (UCK1), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_031432.3

ORF Insert Sequence:

ATGGCTTCGG CGGGAGGCGA AGACTGCGAG AGCCCCGCGC CGGAGGCCGA CCGTCCGCAC 
CAGCGGCCCT TCCTGATAGG GGTGAGCGGC GGCACTGCCA GCGGGAAGTC GACCGTGTGT 
GAGAAGATCA TGGAGTTGCT GGGACAGAAC GAGGTGGAAC AGCGGCAGCG GAAGGTGGTC 
ATCCTGAGCC AGGACAGGTT CTACAAGGTC CTGACGGCAG AGCAGAAGGC CAAGGCCTTG 
AAAGGACAGT ACAATTTTGA CCATCCAGAT GCCTTTGATA ATGATTTGAT GCACAGGACT 
CTGAAGAACA TCGTGGAGGG CAAAACGGTG GAGGTGCCGA CCTATGATTT TGTGACACAC 
TCAAGGTTAC CAGAGACCAC GGTGGTCTAC CCTGCGGACG TGGTTCTGTT TGAGGGCATC 
TTGGTGTTCT ACAGCCAGGA GATCCGGGAC ATGTTCCACC TGCGCCTCTT CGTGGACACC 
GACTCCGACG TCAGGCTGTC TCGAAGAGTT CTCCGGGACG TGCGCCGAGG GAGGGACCTG 
GAGCAGATTC TGACGCAGTA CACCACCTTC GTGAAGCCGG CCTTCGAGGA GTTCTGCCTG 
CCGACAAAGA AGTATGCCGA TGTGATCATC CCGCGAGGAG TGGACAATAT GGTTGCCATC 
AACCTGATCG TGCAGCACAT CCAGGACATT CTGAATGGTG ACATCTGCAA ATGGCACCGA 
GGAGGGTCCA ATGGGCGGAG CTACAAGCGG ACCTTTTCTG AGCCAGGGGA CCACCCTGGG 
ATGCTGACCT CTGGCAAACG GTCACATTTG GAGTCCAGCA GCAGACCCCA CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

UCK1 ( NM_001318519.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001305448.1 Homo sapiens uridine-cytidine kinase 1 (UCK1), transcript variant 5, mRNA.

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CloneID	OHu43535
Clone ID Related Accession (Same CDS sequence)	NM_001318519.1
Accession Version	NM_001318519.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 765bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-04
Organism	Homo sapiens(human)
Product	uridine-cytidine kinase 1 isoform e
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA598285.1, KU178796.1, AK022317.1, AL358781.19 and AA809511.1. On Jan 8, 2016 this sequence version replaced XM_005272225.2. Transcript Variant: This variant (5) uses an alternate in-frame splice site in an internal exon, compared to variant 1. It encodes isoform e which is shorter than isoform a. ##Evidence-Data-START## Transcript exon combination :: SRR1163657.233608.1, SRR1803617.168748.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCTTCGG CGGGAGGCGA AGACTGCGAG AGCCCCGCGC CGGAGGCCGA CCGTCCGCAC 
CAGCGGCCCT TCCTGATAGG GGTGAGCGGC GGCACTGCCA GCGGGAAGTC GACCGTGTGT 
GAGAAGATCA TGGAGTTGCT GGGACAGAAC GAGGTGGAAC AGCGGCAGCG GAAGGTGGTC 
ATCCTGAGCC AGGACAGGTT CTACAAGGTC CTGACGGCAG AGCAGAAGGC CAAGGCCTTG 
AAAGGACAGT ACAATTTTGA CCATCCAGAT GCCTTTGATA ATGATTTGAT GCACAGGACT 
CTGAAGAACA TCGTGGAGGG CAAAACGGTG GAGGTGCCGA CCTATGATTT TGTGACACAC 
TCAAGCCAGG AGATCCGGGA CATGTTCCAC CTGCGCCTCT TCGTGGACAC CGACTCCGAC 
GTCAGGCTGT CTCGAAGAGT TCTCCGGGAC GTGCGCCGAG GGAGGGACCT GGAGCAGATT 
CTGACGCAGT ACACCACCTT CGTGAAGCCG GCCTTCGAGG AGTTCTGCCT GCCGACAAAG 
AAGTATGCCG ATGTGATCAT CCCGCGAGGA GTGGACAATA TGGTTGCCAT CAACCTGATC 
GTGCAGCACA TCCAGGACAT TCTGAATGGT GACATCTGCA AATGGCACCG AGGAGGGTCC 
AATGGGCGGA GCTACAAGCG GACCTTTTCT GAGCCAGGGG ACCACCCTGG GATGCTGACC 
TCTGGCAAAC GGTCACATTT GGAGTCCAGC AGCAGACCCC ACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001305448.1
CDS	102..866
Translation	MASAGGEDCESPAPEADRPHQRPFLIGVSGGTASGKSTVCEKIMELLGQNEVEQRQRKVVILSQDRFYKVLTAEQKAKALKGQYNFDHPDAFDNDLMHRTLKNIVEGKTVEVPTYDFVTHSSQEIRDMFHLRLFVDTDSDVRLSRRVLRDVRRGRDLEQILTQYTTFVKPAFEEFCLPTKKYADVIIPRGVDNMVAINLIVQHIQDILNGDICKWHRGGSNGRSYKRTFSEPGDHPGMLTSGKRSHLESSSRPH

Target ORF information:

RefSeq Version	NM_001318519.1
Organism	Homo sapiens(human)
Definition	Homo sapiens uridine-cytidine kinase 1 (UCK1), transcript variant 5, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001318519.1

ORF Insert Sequence:

ATGGCTTCGG CGGGAGGCGA AGACTGCGAG AGCCCCGCGC CGGAGGCCGA CCGTCCGCAC 
CAGCGGCCCT TCCTGATAGG GGTGAGCGGC GGCACTGCCA GCGGGAAGTC GACCGTGTGT 
GAGAAGATCA TGGAGTTGCT GGGACAGAAC GAGGTGGAAC AGCGGCAGCG GAAGGTGGTC 
ATCCTGAGCC AGGACAGGTT CTACAAGGTC CTGACGGCAG AGCAGAAGGC CAAGGCCTTG 
AAAGGACAGT ACAATTTTGA CCATCCAGAT GCCTTTGATA ATGATTTGAT GCACAGGACT 
CTGAAGAACA TCGTGGAGGG CAAAACGGTG GAGGTGCCGA CCTATGATTT TGTGACACAC 
TCAAGCCAGG AGATCCGGGA CATGTTCCAC CTGCGCCTCT TCGTGGACAC CGACTCCGAC 
GTCAGGCTGT CTCGAAGAGT TCTCCGGGAC GTGCGCCGAG GGAGGGACCT GGAGCAGATT 
CTGACGCAGT ACACCACCTT CGTGAAGCCG GCCTTCGAGG AGTTCTGCCT GCCGACAAAG 
AAGTATGCCG ATGTGATCAT CCCGCGAGGA GTGGACAATA TGGTTGCCAT CAACCTGATC 
GTGCAGCACA TCCAGGACAT TCTGAATGGT GACATCTGCA AATGGCACCG AGGAGGGTCC 
AATGGGCGGA GCTACAAGCG GACCTTTTCT GAGCCAGGGG ACCACCCTGG GATGCTGACC 
TCTGGCAAAC GGTCACATTT GGAGTCCAGC AGCAGACCCC ACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

UCK1 ( XM_005272224.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_005272281.1 Homo sapiens uridine-cytidine kinase 1 (UCK1), transcript variant X1, mRNA.

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CloneID	OHu43534
Clone ID Related Accession (Same CDS sequence)	XM_005272224.2
Accession Version	XM_005272224.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 876bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	uridine-cytidine kinase 1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000009.12) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 12, 2015 this sequence version replaced XM_005272224.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCTTCGG CGGGAGGCGA AGACTGCGAG AGCCCCGCGC CGGAGGCCGA CCGTCCGCAC 
CAGCGGCCCT TCCTGATAGG GGTGAGCGGC GGCACTGCCA GCGGGAAGGA CGAGCGGTTC 
CAGGCGGGAA TCCCGCTTCT GTGTCTCCAG TCGACCGTGT GTGAGAAGAT CATGGAGTTG 
CTGGGACAGA ACGAGGTGGA ACAGCGGCAG CGGAAGGTGG TCATCCTGAG CCAGGACAGG 
TTCTACAAGG TCCTGACGGC AGAGCAGAAG GCCAAGGCCT TGAAAGGACA GTACAATTTT 
GACCATCCAG ATGCCTTTGA TAATGATTTG ATGCACAGGA CTCTGAAGAA CATCGTGGAG 
GGCAAAACGG TGGAGGTGCC GACCTATGAT TTTGTGACAC ACTCAAGGTT ACCAGAGACC 
ACGGTGGTCT ACCCTGCGGA CGTGGTTCTG TTTGAGGGCA TCTTGGTGTT CTACAGCCAG 
GAGATCCGGG ACATGTTCCA CCTGCGCCTC TTCGTGGACA CCGACTCCGA CGTCAGGCTG 
TCTCGAAGAG TTCTCCGGGA CGTGCGCCGA GGGAGGGACC TGGAGCAGAT TCTGACGCAG 
TACACCACCT TCGTGAAGCC GGCCTTCGAG GAGTTCTGCC TGCCGACAAA GAAGTATGCC 
GATGTGATCA TCCCGCGAGG AGTGGACAAT ATGGTTGCCA TCAACCTGAT CGTGCAGCAC 
ATCCAGGACA TTCTGAATGG TGACATCTGC AAATGGCACC GAGGAGGGTC CAATGGGCGG 
AGCTACAAGC GGACCTTTTC TGAGCCAGGG GACCACCCTG GGATGCTGAC CTCTGGCAAA 
CGGTCACATT TGGAGTCCAG CAGCAGACCC CACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005272281.1
CDS	24..899
Translation	MASAGGEDCESPAPEADRPHQRPFLIGVSGGTASGKDERFQAGIPLLCLQSTVCEKIMELLGQNEVEQRQRKVVILSQDRFYKVLTAEQKAKALKGQYNFDHPDAFDNDLMHRTLKNIVEGKTVEVPTYDFVTHSRLPETTVVYPADVVLFEGILVFYSQEIRDMFHLRLFVDTDSDVRLSRRVLRDVRRGRDLEQILTQYTTFVKPAFEEFCLPTKKYADVIIPRGVDNMVAINLIVQHIQDILNGDICKWHRGGSNGRSYKRTFSEPGDHPGMLTSGKRSHLESSSRPH

Target ORF information:

RefSeq Version	XM_005272224.2
Organism	Homo sapiens(human)
Definition	Homo sapiens uridine-cytidine kinase 1 (UCK1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005272224.2

ORF Insert Sequence:

ATGGCTTCGG CGGGAGGCGA AGACTGCGAG AGCCCCGCGC CGGAGGCCGA CCGTCCGCAC 
CAGCGGCCCT TCCTGATAGG GGTGAGCGGC GGCACTGCCA GCGGGAAGGA CGAGCGGTTC 
CAGGCGGGAA TCCCGCTTCT GTGTCTCCAG TCGACCGTGT GTGAGAAGAT CATGGAGTTG 
CTGGGACAGA ACGAGGTGGA ACAGCGGCAG CGGAAGGTGG TCATCCTGAG CCAGGACAGG 
TTCTACAAGG TCCTGACGGC AGAGCAGAAG GCCAAGGCCT TGAAAGGACA GTACAATTTT 
GACCATCCAG ATGCCTTTGA TAATGATTTG ATGCACAGGA CTCTGAAGAA CATCGTGGAG 
GGCAAAACGG TGGAGGTGCC GACCTATGAT TTTGTGACAC ACTCAAGGTT ACCAGAGACC 
ACGGTGGTCT ACCCTGCGGA CGTGGTTCTG TTTGAGGGCA TCTTGGTGTT CTACAGCCAG 
GAGATCCGGG ACATGTTCCA CCTGCGCCTC TTCGTGGACA CCGACTCCGA CGTCAGGCTG 
TCTCGAAGAG TTCTCCGGGA CGTGCGCCGA GGGAGGGACC TGGAGCAGAT TCTGACGCAG 
TACACCACCT TCGTGAAGCC GGCCTTCGAG GAGTTCTGCC TGCCGACAAA GAAGTATGCC 
GATGTGATCA TCCCGCGAGG AGTGGACAAT ATGGTTGCCA TCAACCTGAT CGTGCAGCAC 
ATCCAGGACA TTCTGAATGG TGACATCTGC AAATGGCACC GAGGAGGGTC CAATGGGCGG 
AGCTACAAGC GGACCTTTTC TGAGCCAGGG GACCACCCTG GGATGCTGAC CTCTGGCAAA 
CGGTCACATT TGGAGTCCAG CAGCAGACCC CACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

UCK1 ( NM_031432.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_113620.1 Homo sapiens uridine-cytidine kinase 1 (UCK1), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu15333
Clone ID Related Accession (Same CDS sequence)	NM_031432.5 , NM_031432.4 , NM_031432.3
Accession Version	NM_031432.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 834bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-14
Organism	Homo sapiens(human)
Product	uridine-cytidine kinase 1 isoform a
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AL358781.19. On Aug 31, 2019 this sequence version replaced NM_031432.4. Transcript Variant: This variant (1) represents the predominant transcript and encodes the isoform a. ##Evidence-Data-START## Transcript exon combination :: BC091495.1, AK022317.1 [ECO:0000332] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000372215.5/ ENSP00000361289.4 RefSeq Select criteria :: based on conservation, expression ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGCTTCGG CGGGAGGCGA AGACTGCGAG AGCCCCGCGC CGGAGGCCGA CCGTCCGCAC 
CAGCGGCCCT TCCTGATAGG GGTGAGCGGC GGCACTGCCA GCGGGAAGTC GACCGTGTGT 
GAGAAGATCA TGGAGTTGCT GGGACAGAAC GAGGTGGAAC AGCGGCAGCG GAAGGTGGTC 
ATCCTGAGCC AGGACAGGTT CTACAAGGTC CTGACGGCAG AGCAGAAGGC CAAGGCCTTG 
AAAGGACAGT ACAATTTTGA CCATCCAGAT GCCTTTGATA ATGATTTGAT GCACAGGACT 
CTGAAGAACA TCGTGGAGGG CAAAACGGTG GAGGTGCCGA CCTATGATTT TGTGACACAC 
TCAAGGTTAC CAGAGACCAC GGTGGTCTAC CCTGCGGACG TGGTTCTGTT TGAGGGCATC 
TTGGTGTTCT ACAGCCAGGA GATCCGGGAC ATGTTCCACC TGCGCCTCTT CGTGGACACC 
GACTCCGACG TCAGGCTGTC TCGAAGAGTT CTCCGGGACG TGCGCCGAGG GAGGGACCTG 
GAGCAGATTC TGACGCAGTA CACCACCTTC GTGAAGCCGG CCTTCGAGGA GTTCTGCCTG 
CCGACAAAGA AGTATGCCGA TGTGATCATC CCGCGAGGAG TGGACAATAT GGTTGCCATC 
AACCTGATCG TGCAGCACAT CCAGGACATT CTGAATGGTG ACATCTGCAA ATGGCACCGA 
GGAGGGTCCA ATGGGCGGAG CTACAAGCGG ACCTTTTCTG AGCCAGGGGA CCACCCTGGG 
ATGCTGACCT CTGGCAAACG GTCACATTTG GAGTCCAGCA GCAGACCCCA CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_113620.1
CDS	90..923
Translation	MASAGGEDCESPAPEADRPHQRPFLIGVSGGTASGKSTVCEKIMELLGQNEVEQRQRKVVILSQDRFYKVLTAEQKAKALKGQYNFDHPDAFDNDLMHRTLKNIVEGKTVEVPTYDFVTHSRLPETTVVYPADVVLFEGILVFYSQEIRDMFHLRLFVDTDSDVRLSRRVLRDVRRGRDLEQILTQYTTFVKPAFEEFCLPTKKYADVIIPRGVDNMVAINLIVQHIQDILNGDICKWHRGGSNGRSYKRTFSEPGDHPGMLTSGKRSHLESSSRPH

Target ORF information:

RefSeq Version	NM_031432.5
Organism	Homo sapiens(human)
Definition	Homo sapiens uridine-cytidine kinase 1 (UCK1), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_031432.5

ORF Insert Sequence:

ATGGCTTCGG CGGGAGGCGA AGACTGCGAG AGCCCCGCGC CGGAGGCCGA CCGTCCGCAC 
CAGCGGCCCT TCCTGATAGG GGTGAGCGGC GGCACTGCCA GCGGGAAGTC GACCGTGTGT 
GAGAAGATCA TGGAGTTGCT GGGACAGAAC GAGGTGGAAC AGCGGCAGCG GAAGGTGGTC 
ATCCTGAGCC AGGACAGGTT CTACAAGGTC CTGACGGCAG AGCAGAAGGC CAAGGCCTTG 
AAAGGACAGT ACAATTTTGA CCATCCAGAT GCCTTTGATA ATGATTTGAT GCACAGGACT 
CTGAAGAACA TCGTGGAGGG CAAAACGGTG GAGGTGCCGA CCTATGATTT TGTGACACAC 
TCAAGGTTAC CAGAGACCAC GGTGGTCTAC CCTGCGGACG TGGTTCTGTT TGAGGGCATC 
TTGGTGTTCT ACAGCCAGGA GATCCGGGAC ATGTTCCACC TGCGCCTCTT CGTGGACACC 
GACTCCGACG TCAGGCTGTC TCGAAGAGTT CTCCGGGACG TGCGCCGAGG GAGGGACCTG 
GAGCAGATTC TGACGCAGTA CACCACCTTC GTGAAGCCGG CCTTCGAGGA GTTCTGCCTG 
CCGACAAAGA AGTATGCCGA TGTGATCATC CCGCGAGGAG TGGACAATAT GGTTGCCATC 
AACCTGATCG TGCAGCACAT CCAGGACATT CTGAATGGTG ACATCTGCAA ATGGCACCGA 
GGAGGGTCCA ATGGGCGGAG CTACAAGCGG ACCTTTTCTG AGCCAGGGGA CCACCCTGGG 
ATGCTGACCT CTGGCAAACG GTCACATTTG GAGTCCAGCA GCAGACCCCA CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Purification, activity, and expression levels of two uridine-cytidine kinase isoforms in neuroblastoma cell lines.
Nucleosides, nucleotides & nucleic acids35(10-12)613-618(2016 Dec)
Meinsma R,van Kuilenburg AB

The pivotal role of uridine-cytidine kinases in pyrimidine metabolism and activation of cytotoxic nucleoside analogues in neuroblastoma.
Biochimica et biophysica acta1862(9)1504-12(2016 Sep)
van Kuilenburg AB,Meinsma R

Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing.
Cell164(4)805-17(2016 Feb)
Yang X,Coulombe-Huntington J,Kang S,Sheynkman GM,Hao T,Richardson A,Sun S,Yang F,Shen YA,Murray RR,Spirohn K,Begg BE,Duran-Frigola M,MacWilliams A,Pevzner SJ,Zhong Q,Trigg SA,Tam S,Ghamsari L,Sahni N,Yi S,Rodriguez MD,Balcha D,Tan G,Costanzo M,Andrews B,Boone C,Zhou XJ,Salehi-Ashtiani K,Charloteaux B,Chen AA,Calderwood MA,Aloy P,Roth FP,Hill DE,Iakoucheva LM,Xia Y,Vidal M

Variability of Gene Expression Identifies Transcriptional Regulators of Early Human Embryonic Development.
PLoS genetics11(8)e1005428(2015 Aug)
Hasegawa Y,Taylor D,Ovchinnikov DA,Wolvetang EJ,de Torrent? L,Mar JC

Expression of nucleoside-metabolizing enzymes in myelodysplastic syndromes and modulation of response to azacitidine.
Leukemia28(3)621-8(2014 Mar)
Valencia A,Masala E,Rossi A,Martino A,Sanna A,Buchi F,Canzian F,Cilloni D,Gaidano V,Voso MT,Kosmider O,Fontenay M,Gozzini A,Bosi A,Santini V

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UCK1 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

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