CASP1 gene cDNA ORF clone, Homo sapiens(human)

mRNA	Protein	Name
NM_033293.3	NP_150635.1	caspase-1 isoform gamma
NM_033293.4	NP_150635.1	caspase-1 isoform gamma
NM_001223.5	NP_001214.1	caspase-1 isoform beta precursor
XM_017018394.1	XP_016873883.1	caspase-1 isoform X1
NM_001257118.2	NP_001244047.1	caspase-1 isoform alpha precursor
NM_001257119.2	NP_001244048.1	caspase-1 isoform beta precursor
NM_033292.4	NP_150634.1	caspase-1 isoform alpha precursor
XM_017018395.1	XP_016873884.1	caspase-1 isoform X2
XM_017018396.1	XP_016873885.1	caspase-1 isoform X3
NM_033292.3	NP_150634.1	caspase-1 isoform alpha precursor
XM_017018393.1	XP_016873882.1	caspase-1 isoform X1
NM_001223.4	NP_001214.1	caspase-1 isoform beta precursor
NM_001257119.3	NP_001244048.1	caspase-1 isoform beta precursor
NM_033295.3	NP_150637.1	caspase-1 isoform epsilon
NM_001257118.3	NP_001244047.1	caspase-1 isoform alpha precursor
NM_033294.3	NP_150636.1	caspase-1 isoform delta

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu21385	NM_033292.4 Latest version!	Homo sapiens caspase 1 (CASP1), transcript variant alpha, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
OHu21385	NM_001257118.3 Latest version!	Homo sapiens caspase 1 (CASP1), transcript variant 6, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
OHu21510	NM_033293.4 Latest version!	Homo sapiens caspase 1 (CASP1), transcript variant gamma, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$154.50-$216.30 $309.00
OHu20634	NM_001223.5 Latest version!	Homo sapiens caspase 1 (CASP1), transcript variant beta, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
OHu20634	NM_001257119.3 Latest version!	Homo sapiens caspase 1 (CASP1), transcript variant 7, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
OHu21151	NM_033294.3 Latest version!	Homo sapiens caspase 1 (CASP1), transcript variant delta, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
OHu21774	NM_033295.3 Latest version!	Homo sapiens caspase 1 (CASP1), transcript variant epsilon, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
OHu92572	XM_017018396.1 Latest version!	Homo sapiens caspase 1 (CASP1), transcript variant X4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
OHu92570	XM_017018393.1 Latest version!	Homo sapiens caspase 1 (CASP1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
OHu92570	XM_017018394.1 Latest version!	Homo sapiens caspase 1 (CASP1), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
OHu92571	XM_017018395.1 Latest version!	Homo sapiens caspase 1 (CASP1), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
View Old Accession Versions >>
OHu21510	NM_033293.3	Homo sapiens caspase 1 (CASP1), transcript variant gamma, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$154.50-$216.30 $309.00
OHu21385	NM_033292.3	Homo sapiens caspase 1 (CASP1), transcript variant alpha, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
OHu20634	NM_001223.4	Homo sapiens caspase 1 (CASP1), transcript variant beta, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
OHu20634	NM_001257119.2	Homo sapiens caspase 1 (CASP1), transcript variant 7, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
OHu21385	NM_001257118.2	Homo sapiens caspase 1 (CASP1), transcript variant 6, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
Hide Old Accession Versions >>

CASP1 ( NM_001257118.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001244047.1 Homo sapiens caspase 1 (CASP1), transcript variant 6, mRNA.

Price & Availability↑

CloneID	OHu21385
Clone ID Related Accession (Same CDS sequence)	NM_001257118.2 , NM_033292.4 , NM_033292.3 , NM_001257118.3
Accession Version	NM_001257118.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1215bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-12-05
Organism	Homo sapiens(human)
Product	caspase-1 isoform alpha precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AP001153.5, AK290114.1, KF455483.1 and AA737419.1. On Jan 17, 2014 this sequence version replaced NM_001257118.1. Transcript Variant: This variant (6) differs in the 3' UTR compared to variant alpha. Variant alpha and variant 6 encode the same protein. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1163658.188449.1, SRR1803611.233690.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCCGACA AGGTCCTGAA GGAGAAGAGA AAGCTGTTTA TCCGTTCCAT GGGTGAAGGT 
ACAATAAATG GCTTACTGGA TGAATTATTA CAGACAAGGG TGCTGAACAA GGAAGAGATG 
GAGAAAGTAA AACGTGAAAA TGCTACAGTT ATGGATAAGA CCCGAGCTTT GATTGACTCC 
GTTATTCCGA AAGGGGCACA GGCATGCCAA ATTTGCATCA CATACATTTG TGAAGAAGAC 
AGTTACCTGG CAGGGACGCT GGGACTCTCA GCAGATCAAA CATCTGGAAA TTACCTTAAT 
ATGCAAGACT CTCAAGGAGT ACTTTCTTCC TTTCCAGCTC CTCAGGCAGT GCAGGACAAC 
CCAGCTATGC CCACATCCTC AGGCTCAGAA GGGAATGTCA AGCTTTGCTC CCTAGAAGAA 
GCTCAAAGGA TATGGAAACA AAAGTCGGCA GAGATTTATC CAATAATGGA CAAGTCAAGC 
CGCACACGTC TTGCTCTCAT TATCTGCAAT GAAGAATTTG ACAGTATTCC TAGAAGAACT 
GGAGCTGAGG TTGACATCAC AGGCATGACA ATGCTGCTAC AAAATCTGGG GTACAGCGTA 
GATGTGAAAA AAAATCTCAC TGCTTCGGAC ATGACTACAG AGCTGGAGGC ATTTGCACAC 
CGCCCAGAGC ACAAGACCTC TGACAGCACG TTCCTGGTGT TCATGTCTCA TGGTATTCGG 
GAAGGCATTT GTGGGAAGAA ACACTCTGAG CAAGTCCCAG ATATACTACA ACTCAATGCA 
ATCTTTAACA TGTTGAATAC CAAGAACTGC CCAAGTTTGA AGGACAAACC GAAGGTGATC 
ATCATCCAGG CCTGCCGTGG TGACAGCCCT GGTGTGGTGT GGTTTAAAGA TTCAGTAGGA 
GTTTCTGGAA ACCTATCTTT ACCAACTACA GAAGAGTTTG AGGATGATGC TATTAAGAAA 
GCCCACATAG AGAAGGATTT TATCGCTTTC TGCTCTTCCA CACCAGATAA TGTTTCTTGG 
AGACATCCCA CAATGGGCTC TGTTTTTATT GGAAGACTCA TTGAACATAT GCAAGAATAT 
GCCTGTTCCT GTGATGTGGA GGAAATTTTC CGCAAGGTTC GATTTTCATT TGAGCAGCCA 
GATGGTAGAG CGCAGATGCC CACCACTGAA AGAGTGACTT TGACAAGATG TTTCTACCTC 
TTCCCAGGAC ATTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001244047.1
CDS	45..1259
Translation	MADKVLKEKRKLFIRSMGEGTINGLLDELLQTRVLNKEEMEKVKRENATVMDKTRALIDSVIPKGAQACQICITYICEEDSYLAGTLGLSADQTSGNYLNMQDSQGVLSSFPAPQAVQDNPAMPTSSGSEGNVKLCSLEEAQRIWKQKSAEIYPIMDKSSRTRLALIICNEEFDSIPRRTGAEVDITGMTMLLQNLGYSVDVKKNLTASDMTTELEAFAHRPEHKTSDSTFLVFMSHGIREGICGKKHSEQVPDILQLNAIFNMLNTKNCPSLKDKPKVIIIQACRGDSPGVVWFKDSVGVSGNLSLPTTEEFEDDAIKKAHIEKDFIAFCSSTPDNVSWRHPTMGSVFIGRLIEHMQEYACSCDVEEIFRKVRFSFEQPDGRAQMPTTERVTLTRCFYLFPGH

Target ORF information:

RefSeq Version	NM_001257118.2
Organism	Homo sapiens(human)
Definition	Homo sapiens caspase 1 (CASP1), transcript variant 6, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001257118.2

ORF Insert Sequence:

ATGGCCGACA AGGTCCTGAA GGAGAAGAGA AAGCTGTTTA TCCGTTCCAT GGGTGAAGGT 
ACAATAAATG GCTTACTGGA TGAATTATTA CAGACAAGGG TGCTGAACAA GGAAGAGATG 
GAGAAAGTAA AACGTGAAAA TGCTACAGTT ATGGATAAGA CCCGAGCTTT GATTGACTCC 
GTTATTCCGA AAGGGGCACA GGCATGCCAA ATTTGCATCA CATACATTTG TGAAGAAGAC 
AGTTACCTGG CAGGGACGCT GGGACTCTCA GCAGATCAAA CATCTGGAAA TTACCTTAAT 
ATGCAAGACT CTCAAGGAGT ACTTTCTTCC TTTCCAGCTC CTCAGGCAGT GCAGGACAAC 
CCAGCTATGC CCACATCCTC AGGCTCAGAA GGGAATGTCA AGCTTTGCTC CCTAGAAGAA 
GCTCAAAGGA TATGGAAACA AAAGTCGGCA GAGATTTATC CAATAATGGA CAAGTCAAGC 
CGCACACGTC TTGCTCTCAT TATCTGCAAT GAAGAATTTG ACAGTATTCC TAGAAGAACT 
GGAGCTGAGG TTGACATCAC AGGCATGACA ATGCTGCTAC AAAATCTGGG GTACAGCGTA 
GATGTGAAAA AAAATCTCAC TGCTTCGGAC ATGACTACAG AGCTGGAGGC ATTTGCACAC 
CGCCCAGAGC ACAAGACCTC TGACAGCACG TTCCTGGTGT TCATGTCTCA TGGTATTCGG 
GAAGGCATTT GTGGGAAGAA ACACTCTGAG CAAGTCCCAG ATATACTACA ACTCAATGCA 
ATCTTTAACA TGTTGAATAC CAAGAACTGC CCAAGTTTGA AGGACAAACC GAAGGTGATC 
ATCATCCAGG CCTGCCGTGG TGACAGCCCT GGTGTGGTGT GGTTTAAAGA TTCAGTAGGA 
GTTTCTGGAA ACCTATCTTT ACCAACTACA GAAGAGTTTG AGGATGATGC TATTAAGAAA 
GCCCACATAG AGAAGGATTT TATCGCTTTC TGCTCTTCCA CACCAGATAA TGTTTCTTGG 
AGACATCCCA CAATGGGCTC TGTTTTTATT GGAAGACTCA TTGAACATAT GCAAGAATAT 
GCCTGTTCCT GTGATGTGGA GGAAATTTTC CGCAAGGTTC GATTTTCATT TGAGCAGCCA 
GATGGTAGAG CGCAGATGCC CACCACTGAA AGAGTGACTT TGACAAGATG TTTCTACCTC 
TTCCCAGGAC ATTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CASP1 ( NM_033292.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_150634.1 Homo sapiens caspase 1 (CASP1), transcript variant alpha, mRNA.

Price & Availability↑

CloneID	OHu21385
Clone ID Related Accession (Same CDS sequence)	NM_001257118.2 , NM_033292.4 , NM_033292.3 , NM_001257118.3
Accession Version	NM_033292.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1215bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-21
Organism	Homo sapiens(human)
Product	caspase-1 isoform alpha precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AP001153.5, M87507.1, AA505065.1 and KF455483.1. This sequence is a reference standard in the RefSeqGene project. On May 31, 2019 this sequence version replaced NM_033292.3. Transcript Variant: This variant (alpha) encodes the longest isoform (alpha). Variant alpha and variant 6 encode the same protein. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1163655.19790.1, SRR1163655.118063.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCCGACA AGGTCCTGAA GGAGAAGAGA AAGCTGTTTA TCCGTTCCAT GGGTGAAGGT 
ACAATAAATG GCTTACTGGA TGAATTATTA CAGACAAGGG TGCTGAACAA GGAAGAGATG 
GAGAAAGTAA AACGTGAAAA TGCTACAGTT ATGGATAAGA CCCGAGCTTT GATTGACTCC 
GTTATTCCGA AAGGGGCACA GGCATGCCAA ATTTGCATCA CATACATTTG TGAAGAAGAC 
AGTTACCTGG CAGGGACGCT GGGACTCTCA GCAGATCAAA CATCTGGAAA TTACCTTAAT 
ATGCAAGACT CTCAAGGAGT ACTTTCTTCC TTTCCAGCTC CTCAGGCAGT GCAGGACAAC 
CCAGCTATGC CCACATCCTC AGGCTCAGAA GGGAATGTCA AGCTTTGCTC CCTAGAAGAA 
GCTCAAAGGA TATGGAAACA AAAGTCGGCA GAGATTTATC CAATAATGGA CAAGTCAAGC 
CGCACACGTC TTGCTCTCAT TATCTGCAAT GAAGAATTTG ACAGTATTCC TAGAAGAACT 
GGAGCTGAGG TTGACATCAC AGGCATGACA ATGCTGCTAC AAAATCTGGG GTACAGCGTA 
GATGTGAAAA AAAATCTCAC TGCTTCGGAC ATGACTACAG AGCTGGAGGC ATTTGCACAC 
CGCCCAGAGC ACAAGACCTC TGACAGCACG TTCCTGGTGT TCATGTCTCA TGGTATTCGG 
GAAGGCATTT GTGGGAAGAA ACACTCTGAG CAAGTCCCAG ATATACTACA ACTCAATGCA 
ATCTTTAACA TGTTGAATAC CAAGAACTGC CCAAGTTTGA AGGACAAACC GAAGGTGATC 
ATCATCCAGG CCTGCCGTGG TGACAGCCCT GGTGTGGTGT GGTTTAAAGA TTCAGTAGGA 
GTTTCTGGAA ACCTATCTTT ACCAACTACA GAAGAGTTTG AGGATGATGC TATTAAGAAA 
GCCCACATAG AGAAGGATTT TATCGCTTTC TGCTCTTCCA CACCAGATAA TGTTTCTTGG 
AGACATCCCA CAATGGGCTC TGTTTTTATT GGAAGACTCA TTGAACATAT GCAAGAATAT 
GCCTGTTCCT GTGATGTGGA GGAAATTTTC CGCAAGGTTC GATTTTCATT TGAGCAGCCA 
GATGGTAGAG CGCAGATGCC CACCACTGAA AGAGTGACTT TGACAAGATG TTTCTACCTC 
TTCCCAGGAC ATTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_150634.1
CDS	32..1246
Translation	MADKVLKEKRKLFIRSMGEGTINGLLDELLQTRVLNKEEMEKVKRENATVMDKTRALIDSVIPKGAQACQICITYICEEDSYLAGTLGLSADQTSGNYLNMQDSQGVLSSFPAPQAVQDNPAMPTSSGSEGNVKLCSLEEAQRIWKQKSAEIYPIMDKSSRTRLALIICNEEFDSIPRRTGAEVDITGMTMLLQNLGYSVDVKKNLTASDMTTELEAFAHRPEHKTSDSTFLVFMSHGIREGICGKKHSEQVPDILQLNAIFNMLNTKNCPSLKDKPKVIIIQACRGDSPGVVWFKDSVGVSGNLSLPTTEEFEDDAIKKAHIEKDFIAFCSSTPDNVSWRHPTMGSVFIGRLIEHMQEYACSCDVEEIFRKVRFSFEQPDGRAQMPTTERVTLTRCFYLFPGH

Target ORF information:

RefSeq Version	NM_033292.4
Organism	Homo sapiens(human)
Definition	Homo sapiens caspase 1 (CASP1), transcript variant alpha, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_033292.4

ORF Insert Sequence:

ATGGCCGACA AGGTCCTGAA GGAGAAGAGA AAGCTGTTTA TCCGTTCCAT GGGTGAAGGT 
ACAATAAATG GCTTACTGGA TGAATTATTA CAGACAAGGG TGCTGAACAA GGAAGAGATG 
GAGAAAGTAA AACGTGAAAA TGCTACAGTT ATGGATAAGA CCCGAGCTTT GATTGACTCC 
GTTATTCCGA AAGGGGCACA GGCATGCCAA ATTTGCATCA CATACATTTG TGAAGAAGAC 
AGTTACCTGG CAGGGACGCT GGGACTCTCA GCAGATCAAA CATCTGGAAA TTACCTTAAT 
ATGCAAGACT CTCAAGGAGT ACTTTCTTCC TTTCCAGCTC CTCAGGCAGT GCAGGACAAC 
CCAGCTATGC CCACATCCTC AGGCTCAGAA GGGAATGTCA AGCTTTGCTC CCTAGAAGAA 
GCTCAAAGGA TATGGAAACA AAAGTCGGCA GAGATTTATC CAATAATGGA CAAGTCAAGC 
CGCACACGTC TTGCTCTCAT TATCTGCAAT GAAGAATTTG ACAGTATTCC TAGAAGAACT 
GGAGCTGAGG TTGACATCAC AGGCATGACA ATGCTGCTAC AAAATCTGGG GTACAGCGTA 
GATGTGAAAA AAAATCTCAC TGCTTCGGAC ATGACTACAG AGCTGGAGGC ATTTGCACAC 
CGCCCAGAGC ACAAGACCTC TGACAGCACG TTCCTGGTGT TCATGTCTCA TGGTATTCGG 
GAAGGCATTT GTGGGAAGAA ACACTCTGAG CAAGTCCCAG ATATACTACA ACTCAATGCA 
ATCTTTAACA TGTTGAATAC CAAGAACTGC CCAAGTTTGA AGGACAAACC GAAGGTGATC 
ATCATCCAGG CCTGCCGTGG TGACAGCCCT GGTGTGGTGT GGTTTAAAGA TTCAGTAGGA 
GTTTCTGGAA ACCTATCTTT ACCAACTACA GAAGAGTTTG AGGATGATGC TATTAAGAAA 
GCCCACATAG AGAAGGATTT TATCGCTTTC TGCTCTTCCA CACCAGATAA TGTTTCTTGG 
AGACATCCCA CAATGGGCTC TGTTTTTATT GGAAGACTCA TTGAACATAT GCAAGAATAT 
GCCTGTTCCT GTGATGTGGA GGAAATTTTC CGCAAGGTTC GATTTTCATT TGAGCAGCCA 
GATGGTAGAG CGCAGATGCC CACCACTGAA AGAGTGACTT TGACAAGATG TTTCTACCTC 
TTCCCAGGAC ATTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CASP1 ( NM_033292.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_150634.1 Homo sapiens caspase 1 (CASP1), transcript variant alpha, mRNA.

Price & Availability↑

CloneID	OHu21385
Clone ID Related Accession (Same CDS sequence)	NM_001257118.2 , NM_033292.4 , NM_033292.3 , NM_001257118.3
Accession Version	NM_033292.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1215bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-01-12
Organism	Homo sapiens(human)
Product	caspase-1 isoform alpha precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AP001153.5, M87507.1 and AA505065.1. This sequence is a reference standard in the RefSeqGene project. On Mar 14, 2012 this sequence version replaced NM_033292.2. Transcript Variant: This variant (alpha) encodes the longest isoform (alpha). Variant alpha and variant 6 encode the same protein. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1163655.169624.1, SRR1163657.581602.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCCGACA AGGTCCTGAA GGAGAAGAGA AAGCTGTTTA TCCGTTCCAT GGGTGAAGGT 
ACAATAAATG GCTTACTGGA TGAATTATTA CAGACAAGGG TGCTGAACAA GGAAGAGATG 
GAGAAAGTAA AACGTGAAAA TGCTACAGTT ATGGATAAGA CCCGAGCTTT GATTGACTCC 
GTTATTCCGA AAGGGGCACA GGCATGCCAA ATTTGCATCA CATACATTTG TGAAGAAGAC 
AGTTACCTGG CAGGGACGCT GGGACTCTCA GCAGATCAAA CATCTGGAAA TTACCTTAAT 
ATGCAAGACT CTCAAGGAGT ACTTTCTTCC TTTCCAGCTC CTCAGGCAGT GCAGGACAAC 
CCAGCTATGC CCACATCCTC AGGCTCAGAA GGGAATGTCA AGCTTTGCTC CCTAGAAGAA 
GCTCAAAGGA TATGGAAACA AAAGTCGGCA GAGATTTATC CAATAATGGA CAAGTCAAGC 
CGCACACGTC TTGCTCTCAT TATCTGCAAT GAAGAATTTG ACAGTATTCC TAGAAGAACT 
GGAGCTGAGG TTGACATCAC AGGCATGACA ATGCTGCTAC AAAATCTGGG GTACAGCGTA 
GATGTGAAAA AAAATCTCAC TGCTTCGGAC ATGACTACAG AGCTGGAGGC ATTTGCACAC 
CGCCCAGAGC ACAAGACCTC TGACAGCACG TTCCTGGTGT TCATGTCTCA TGGTATTCGG 
GAAGGCATTT GTGGGAAGAA ACACTCTGAG CAAGTCCCAG ATATACTACA ACTCAATGCA 
ATCTTTAACA TGTTGAATAC CAAGAACTGC CCAAGTTTGA AGGACAAACC GAAGGTGATC 
ATCATCCAGG CCTGCCGTGG TGACAGCCCT GGTGTGGTGT GGTTTAAAGA TTCAGTAGGA 
GTTTCTGGAA ACCTATCTTT ACCAACTACA GAAGAGTTTG AGGATGATGC TATTAAGAAA 
GCCCACATAG AGAAGGATTT TATCGCTTTC TGCTCTTCCA CACCAGATAA TGTTTCTTGG 
AGACATCCCA CAATGGGCTC TGTTTTTATT GGAAGACTCA TTGAACATAT GCAAGAATAT 
GCCTGTTCCT GTGATGTGGA GGAAATTTTC CGCAAGGTTC GATTTTCATT TGAGCAGCCA 
GATGGTAGAG CGCAGATGCC CACCACTGAA AGAGTGACTT TGACAAGATG TTTCTACCTC 
TTCCCAGGAC ATTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_150634.1
CDS	45..1259
Translation	MADKVLKEKRKLFIRSMGEGTINGLLDELLQTRVLNKEEMEKVKRENATVMDKTRALIDSVIPKGAQACQICITYICEEDSYLAGTLGLSADQTSGNYLNMQDSQGVLSSFPAPQAVQDNPAMPTSSGSEGNVKLCSLEEAQRIWKQKSAEIYPIMDKSSRTRLALIICNEEFDSIPRRTGAEVDITGMTMLLQNLGYSVDVKKNLTASDMTTELEAFAHRPEHKTSDSTFLVFMSHGIREGICGKKHSEQVPDILQLNAIFNMLNTKNCPSLKDKPKVIIIQACRGDSPGVVWFKDSVGVSGNLSLPTTEEFEDDAIKKAHIEKDFIAFCSSTPDNVSWRHPTMGSVFIGRLIEHMQEYACSCDVEEIFRKVRFSFEQPDGRAQMPTTERVTLTRCFYLFPGH

Target ORF information:

RefSeq Version	NM_033292.3
Organism	Homo sapiens(human)
Definition	Homo sapiens caspase 1 (CASP1), transcript variant alpha, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_033292.3

ORF Insert Sequence:

ATGGCCGACA AGGTCCTGAA GGAGAAGAGA AAGCTGTTTA TCCGTTCCAT GGGTGAAGGT 
ACAATAAATG GCTTACTGGA TGAATTATTA CAGACAAGGG TGCTGAACAA GGAAGAGATG 
GAGAAAGTAA AACGTGAAAA TGCTACAGTT ATGGATAAGA CCCGAGCTTT GATTGACTCC 
GTTATTCCGA AAGGGGCACA GGCATGCCAA ATTTGCATCA CATACATTTG TGAAGAAGAC 
AGTTACCTGG CAGGGACGCT GGGACTCTCA GCAGATCAAA CATCTGGAAA TTACCTTAAT 
ATGCAAGACT CTCAAGGAGT ACTTTCTTCC TTTCCAGCTC CTCAGGCAGT GCAGGACAAC 
CCAGCTATGC CCACATCCTC AGGCTCAGAA GGGAATGTCA AGCTTTGCTC CCTAGAAGAA 
GCTCAAAGGA TATGGAAACA AAAGTCGGCA GAGATTTATC CAATAATGGA CAAGTCAAGC 
CGCACACGTC TTGCTCTCAT TATCTGCAAT GAAGAATTTG ACAGTATTCC TAGAAGAACT 
GGAGCTGAGG TTGACATCAC AGGCATGACA ATGCTGCTAC AAAATCTGGG GTACAGCGTA 
GATGTGAAAA AAAATCTCAC TGCTTCGGAC ATGACTACAG AGCTGGAGGC ATTTGCACAC 
CGCCCAGAGC ACAAGACCTC TGACAGCACG TTCCTGGTGT TCATGTCTCA TGGTATTCGG 
GAAGGCATTT GTGGGAAGAA ACACTCTGAG CAAGTCCCAG ATATACTACA ACTCAATGCA 
ATCTTTAACA TGTTGAATAC CAAGAACTGC CCAAGTTTGA AGGACAAACC GAAGGTGATC 
ATCATCCAGG CCTGCCGTGG TGACAGCCCT GGTGTGGTGT GGTTTAAAGA TTCAGTAGGA 
GTTTCTGGAA ACCTATCTTT ACCAACTACA GAAGAGTTTG AGGATGATGC TATTAAGAAA 
GCCCACATAG AGAAGGATTT TATCGCTTTC TGCTCTTCCA CACCAGATAA TGTTTCTTGG 
AGACATCCCA CAATGGGCTC TGTTTTTATT GGAAGACTCA TTGAACATAT GCAAGAATAT 
GCCTGTTCCT GTGATGTGGA GGAAATTTTC CGCAAGGTTC GATTTTCATT TGAGCAGCCA 
GATGGTAGAG CGCAGATGCC CACCACTGAA AGAGTGACTT TGACAAGATG TTTCTACCTC 
TTCCCAGGAC ATTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CASP1 ( NM_001257118.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_001244047.1 Homo sapiens caspase 1 (CASP1), transcript variant 6, mRNA.

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CloneID	OHu21385
Clone ID Related Accession (Same CDS sequence)	NM_001257118.2 , NM_033292.4 , NM_033292.3 , NM_001257118.3
Accession Version	NM_001257118.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1215bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-07-01
Organism	Homo sapiens(human)
Product	caspase-1 isoform alpha precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK290114.1, AP001153.5, KF455483.1 and AA737419.1. On Nov 22, 2018 this sequence version replaced NM_001257118.2. Transcript Variant: This variant (6) differs in the 3' UTR compared to variant alpha. Variant alpha and variant 6 encode the same protein. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803615.467794.1, SRR1163658.188449.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000533400.6/ ENSP00000433138.1 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGCCGACA AGGTCCTGAA GGAGAAGAGA AAGCTGTTTA TCCGTTCCAT GGGTGAAGGT 
ACAATAAATG GCTTACTGGA TGAATTATTA CAGACAAGGG TGCTGAACAA GGAAGAGATG 
GAGAAAGTAA AACGTGAAAA TGCTACAGTT ATGGATAAGA CCCGAGCTTT GATTGACTCC 
GTTATTCCGA AAGGGGCACA GGCATGCCAA ATTTGCATCA CATACATTTG TGAAGAAGAC 
AGTTACCTGG CAGGGACGCT GGGACTCTCA GCAGATCAAA CATCTGGAAA TTACCTTAAT 
ATGCAAGACT CTCAAGGAGT ACTTTCTTCC TTTCCAGCTC CTCAGGCAGT GCAGGACAAC 
CCAGCTATGC CCACATCCTC AGGCTCAGAA GGGAATGTCA AGCTTTGCTC CCTAGAAGAA 
GCTCAAAGGA TATGGAAACA AAAGTCGGCA GAGATTTATC CAATAATGGA CAAGTCAAGC 
CGCACACGTC TTGCTCTCAT TATCTGCAAT GAAGAATTTG ACAGTATTCC TAGAAGAACT 
GGAGCTGAGG TTGACATCAC AGGCATGACA ATGCTGCTAC AAAATCTGGG GTACAGCGTA 
GATGTGAAAA AAAATCTCAC TGCTTCGGAC ATGACTACAG AGCTGGAGGC ATTTGCACAC 
CGCCCAGAGC ACAAGACCTC TGACAGCACG TTCCTGGTGT TCATGTCTCA TGGTATTCGG 
GAAGGCATTT GTGGGAAGAA ACACTCTGAG CAAGTCCCAG ATATACTACA ACTCAATGCA 
ATCTTTAACA TGTTGAATAC CAAGAACTGC CCAAGTTTGA AGGACAAACC GAAGGTGATC 
ATCATCCAGG CCTGCCGTGG TGACAGCCCT GGTGTGGTGT GGTTTAAAGA TTCAGTAGGA 
GTTTCTGGAA ACCTATCTTT ACCAACTACA GAAGAGTTTG AGGATGATGC TATTAAGAAA 
GCCCACATAG AGAAGGATTT TATCGCTTTC TGCTCTTCCA CACCAGATAA TGTTTCTTGG 
AGACATCCCA CAATGGGCTC TGTTTTTATT GGAAGACTCA TTGAACATAT GCAAGAATAT 
GCCTGTTCCT GTGATGTGGA GGAAATTTTC CGCAAGGTTC GATTTTCATT TGAGCAGCCA 
GATGGTAGAG CGCAGATGCC CACCACTGAA AGAGTGACTT TGACAAGATG TTTCTACCTC 
TTCCCAGGAC ATTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001244047.1
CDS	32..1246
Translation	MADKVLKEKRKLFIRSMGEGTINGLLDELLQTRVLNKEEMEKVKRENATVMDKTRALIDSVIPKGAQACQICITYICEEDSYLAGTLGLSADQTSGNYLNMQDSQGVLSSFPAPQAVQDNPAMPTSSGSEGNVKLCSLEEAQRIWKQKSAEIYPIMDKSSRTRLALIICNEEFDSIPRRTGAEVDITGMTMLLQNLGYSVDVKKNLTASDMTTELEAFAHRPEHKTSDSTFLVFMSHGIREGICGKKHSEQVPDILQLNAIFNMLNTKNCPSLKDKPKVIIIQACRGDSPGVVWFKDSVGVSGNLSLPTTEEFEDDAIKKAHIEKDFIAFCSSTPDNVSWRHPTMGSVFIGRLIEHMQEYACSCDVEEIFRKVRFSFEQPDGRAQMPTTERVTLTRCFYLFPGH

Target ORF information:

RefSeq Version	NM_001257118.3
Organism	Homo sapiens(human)
Definition	Homo sapiens caspase 1 (CASP1), transcript variant 6, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001257118.3

ORF Insert Sequence:

ATGGCCGACA AGGTCCTGAA GGAGAAGAGA AAGCTGTTTA TCCGTTCCAT GGGTGAAGGT 
ACAATAAATG GCTTACTGGA TGAATTATTA CAGACAAGGG TGCTGAACAA GGAAGAGATG 
GAGAAAGTAA AACGTGAAAA TGCTACAGTT ATGGATAAGA CCCGAGCTTT GATTGACTCC 
GTTATTCCGA AAGGGGCACA GGCATGCCAA ATTTGCATCA CATACATTTG TGAAGAAGAC 
AGTTACCTGG CAGGGACGCT GGGACTCTCA GCAGATCAAA CATCTGGAAA TTACCTTAAT 
ATGCAAGACT CTCAAGGAGT ACTTTCTTCC TTTCCAGCTC CTCAGGCAGT GCAGGACAAC 
CCAGCTATGC CCACATCCTC AGGCTCAGAA GGGAATGTCA AGCTTTGCTC CCTAGAAGAA 
GCTCAAAGGA TATGGAAACA AAAGTCGGCA GAGATTTATC CAATAATGGA CAAGTCAAGC 
CGCACACGTC TTGCTCTCAT TATCTGCAAT GAAGAATTTG ACAGTATTCC TAGAAGAACT 
GGAGCTGAGG TTGACATCAC AGGCATGACA ATGCTGCTAC AAAATCTGGG GTACAGCGTA 
GATGTGAAAA AAAATCTCAC TGCTTCGGAC ATGACTACAG AGCTGGAGGC ATTTGCACAC 
CGCCCAGAGC ACAAGACCTC TGACAGCACG TTCCTGGTGT TCATGTCTCA TGGTATTCGG 
GAAGGCATTT GTGGGAAGAA ACACTCTGAG CAAGTCCCAG ATATACTACA ACTCAATGCA 
ATCTTTAACA TGTTGAATAC CAAGAACTGC CCAAGTTTGA AGGACAAACC GAAGGTGATC 
ATCATCCAGG CCTGCCGTGG TGACAGCCCT GGTGTGGTGT GGTTTAAAGA TTCAGTAGGA 
GTTTCTGGAA ACCTATCTTT ACCAACTACA GAAGAGTTTG AGGATGATGC TATTAAGAAA 
GCCCACATAG AGAAGGATTT TATCGCTTTC TGCTCTTCCA CACCAGATAA TGTTTCTTGG 
AGACATCCCA CAATGGGCTC TGTTTTTATT GGAAGACTCA TTGAACATAT GCAAGAATAT 
GCCTGTTCCT GTGATGTGGA GGAAATTTTC CGCAAGGTTC GATTTTCATT TGAGCAGCCA 
GATGGTAGAG CGCAGATGCC CACCACTGAA AGAGTGACTT TGACAAGATG TTTCTACCTC 
TTCCCAGGAC ATTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CASP1 ( NM_033293.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_150635.1 Homo sapiens caspase 1 (CASP1), transcript variant gamma, mRNA.

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CloneID	OHu21510
Clone ID Related Accession (Same CDS sequence)	NM_033293.3 , NM_033293.4
Accession Version	NM_033293.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 936bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-01-12
Organism	Homo sapiens(human)
Product	caspase-1 isoform gamma
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AP001153.5, U13698.1 and AA761907.1. On Mar 14, 2012 this sequence version replaced NM_033293.2. Transcript Variant: This variant (gamma) has multiple differences in the coding region but the translation remains in frame, compared to variant alpha. Variant gamma encodes a protein lacking an internal segment, as compared to isoform alpha. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC062327.1, SRR1163657.256775.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCCGACA AGGTCCTGAA GGAGAAGAGA AAGCTGTTTA TCCGTTCCAT GGGTGAAGCT 
CCTCAGGCAG TGCAGGACAA CCCAGCTATG CCCACATCCT CAGGCTCAGA AGGGAATGTC 
AAGCTTTGCT CCCTAGAAGA AGCTCAAAGG ATATGGAAAC AAAAGTCGGC AGAGATTTAT 
CCAATAATGG ACAAGTCAAG CCGCACACGT CTTGCTCTCA TTATCTGCAA TGAAGAATTT 
GACAGTATTC CTAGAAGAAC TGGAGCTGAG GTTGACATCA CAGGCATGAC AATGCTGCTA 
CAAAATCTGG GGTACAGCGT AGATGTGAAA AAAAATCTCA CTGCTTCGGA CATGACTACA 
GAGCTGGAGG CATTTGCACA CCGCCCAGAG CACAAGACCT CTGACAGCAC GTTCCTGGTG 
TTCATGTCTC ATGGTATTCG GGAAGGCATT TGTGGGAAGA AACACTCTGA GCAAGTCCCA 
GATATACTAC AACTCAATGC AATCTTTAAC ATGTTGAATA CCAAGAACTG CCCAAGTTTG 
AAGGACAAAC CGAAGGTGAT CATCATCCAG GCCTGCCGTG GTGACAGCCC TGGTGTGGTG 
TGGTTTAAAG ATTCAGTAGG AGTTTCTGGA AACCTATCTT TACCAACTAC AGAAGAGTTT 
GAGGATGATG CTATTAAGAA AGCCCACATA GAGAAGGATT TTATCGCTTT CTGCTCTTCC 
ACACCAGATA ATGTTTCTTG GAGACATCCC ACAATGGGCT CTGTTTTTAT TGGAAGACTC 
ATTGAACATA TGCAAGAATA TGCCTGTTCC TGTGATGTGG AGGAAATTTT CCGCAAGGTT 
CGATTTTCAT TTGAGCAGCC AGATGGTAGA GCGCAGATGC CCACCACTGA AAGAGTGACT 
TTGACAAGAT GTTTCTACCT CTTCCCAGGA CATTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_150635.1
CDS	45..980
Translation	MADKVLKEKRKLFIRSMGEAPQAVQDNPAMPTSSGSEGNVKLCSLEEAQRIWKQKSAEIYPIMDKSSRTRLALIICNEEFDSIPRRTGAEVDITGMTMLLQNLGYSVDVKKNLTASDMTTELEAFAHRPEHKTSDSTFLVFMSHGIREGICGKKHSEQVPDILQLNAIFNMLNTKNCPSLKDKPKVIIIQACRGDSPGVVWFKDSVGVSGNLSLPTTEEFEDDAIKKAHIEKDFIAFCSSTPDNVSWRHPTMGSVFIGRLIEHMQEYACSCDVEEIFRKVRFSFEQPDGRAQMPTTERVTLTRCFYLFPGH

Target ORF information:

RefSeq Version	NM_033293.3
Organism	Homo sapiens(human)
Definition	Homo sapiens caspase 1 (CASP1), transcript variant gamma, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_033293.3

ORF Insert Sequence:

ATGGCCGACA AGGTCCTGAA GGAGAAGAGA AAGCTGTTTA TCCGTTCCAT GGGTGAAGCT 
CCTCAGGCAG TGCAGGACAA CCCAGCTATG CCCACATCCT CAGGCTCAGA AGGGAATGTC 
AAGCTTTGCT CCCTAGAAGA AGCTCAAAGG ATATGGAAAC AAAAGTCGGC AGAGATTTAT 
CCAATAATGG ACAAGTCAAG CCGCACACGT CTTGCTCTCA TTATCTGCAA TGAAGAATTT 
GACAGTATTC CTAGAAGAAC TGGAGCTGAG GTTGACATCA CAGGCATGAC AATGCTGCTA 
CAAAATCTGG GGTACAGCGT AGATGTGAAA AAAAATCTCA CTGCTTCGGA CATGACTACA 
GAGCTGGAGG CATTTGCACA CCGCCCAGAG CACAAGACCT CTGACAGCAC GTTCCTGGTG 
TTCATGTCTC ATGGTATTCG GGAAGGCATT TGTGGGAAGA AACACTCTGA GCAAGTCCCA 
GATATACTAC AACTCAATGC AATCTTTAAC ATGTTGAATA CCAAGAACTG CCCAAGTTTG 
AAGGACAAAC CGAAGGTGAT CATCATCCAG GCCTGCCGTG GTGACAGCCC TGGTGTGGTG 
TGGTTTAAAG ATTCAGTAGG AGTTTCTGGA AACCTATCTT TACCAACTAC AGAAGAGTTT 
GAGGATGATG CTATTAAGAA AGCCCACATA GAGAAGGATT TTATCGCTTT CTGCTCTTCC 
ACACCAGATA ATGTTTCTTG GAGACATCCC ACAATGGGCT CTGTTTTTAT TGGAAGACTC 
ATTGAACATA TGCAAGAATA TGCCTGTTCC TGTGATGTGG AGGAAATTTT CCGCAAGGTT 
CGATTTTCAT TTGAGCAGCC AGATGGTAGA GCGCAGATGC CCACCACTGA AAGAGTGACT 
TTGACAAGAT GTTTCTACCT CTTCCCAGGA CATTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CASP1 ( NM_033293.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_150635.1 Homo sapiens caspase 1 (CASP1), transcript variant gamma, mRNA.

Price & Availability↑

CloneID	OHu21510
Clone ID Related Accession (Same CDS sequence)	NM_033293.3 , NM_033293.4
Accession Version	NM_033293.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 936bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-07-01
Organism	Homo sapiens(human)
Product	caspase-1 isoform gamma
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AP001153.5, U13698.1, AA761907.1 and KF455483.1. On May 31, 2019 this sequence version replaced NM_033293.3. Transcript Variant: This variant (gamma) has multiple differences in the coding region but the translation remains in frame, compared to variant alpha. Variant gamma encodes a protein lacking an internal segment, as compared to isoform alpha. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC062327.1, SRR1163657.256775.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCCGACA AGGTCCTGAA GGAGAAGAGA AAGCTGTTTA TCCGTTCCAT GGGTGAAGCT 
CCTCAGGCAG TGCAGGACAA CCCAGCTATG CCCACATCCT CAGGCTCAGA AGGGAATGTC 
AAGCTTTGCT CCCTAGAAGA AGCTCAAAGG ATATGGAAAC AAAAGTCGGC AGAGATTTAT 
CCAATAATGG ACAAGTCAAG CCGCACACGT CTTGCTCTCA TTATCTGCAA TGAAGAATTT 
GACAGTATTC CTAGAAGAAC TGGAGCTGAG GTTGACATCA CAGGCATGAC AATGCTGCTA 
CAAAATCTGG GGTACAGCGT AGATGTGAAA AAAAATCTCA CTGCTTCGGA CATGACTACA 
GAGCTGGAGG CATTTGCACA CCGCCCAGAG CACAAGACCT CTGACAGCAC GTTCCTGGTG 
TTCATGTCTC ATGGTATTCG GGAAGGCATT TGTGGGAAGA AACACTCTGA GCAAGTCCCA 
GATATACTAC AACTCAATGC AATCTTTAAC ATGTTGAATA CCAAGAACTG CCCAAGTTTG 
AAGGACAAAC CGAAGGTGAT CATCATCCAG GCCTGCCGTG GTGACAGCCC TGGTGTGGTG 
TGGTTTAAAG ATTCAGTAGG AGTTTCTGGA AACCTATCTT TACCAACTAC AGAAGAGTTT 
GAGGATGATG CTATTAAGAA AGCCCACATA GAGAAGGATT TTATCGCTTT CTGCTCTTCC 
ACACCAGATA ATGTTTCTTG GAGACATCCC ACAATGGGCT CTGTTTTTAT TGGAAGACTC 
ATTGAACATA TGCAAGAATA TGCCTGTTCC TGTGATGTGG AGGAAATTTT CCGCAAGGTT 
CGATTTTCAT TTGAGCAGCC AGATGGTAGA GCGCAGATGC CCACCACTGA AAGAGTGACT 
TTGACAAGAT GTTTCTACCT CTTCCCAGGA CATTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_150635.1
CDS	32..967
Translation	MADKVLKEKRKLFIRSMGEAPQAVQDNPAMPTSSGSEGNVKLCSLEEAQRIWKQKSAEIYPIMDKSSRTRLALIICNEEFDSIPRRTGAEVDITGMTMLLQNLGYSVDVKKNLTASDMTTELEAFAHRPEHKTSDSTFLVFMSHGIREGICGKKHSEQVPDILQLNAIFNMLNTKNCPSLKDKPKVIIIQACRGDSPGVVWFKDSVGVSGNLSLPTTEEFEDDAIKKAHIEKDFIAFCSSTPDNVSWRHPTMGSVFIGRLIEHMQEYACSCDVEEIFRKVRFSFEQPDGRAQMPTTERVTLTRCFYLFPGH

Target ORF information:

RefSeq Version	NM_033293.4
Organism	Homo sapiens(human)
Definition	Homo sapiens caspase 1 (CASP1), transcript variant gamma, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_033293.4

ORF Insert Sequence:

ATGGCCGACA AGGTCCTGAA GGAGAAGAGA AAGCTGTTTA TCCGTTCCAT GGGTGAAGCT 
CCTCAGGCAG TGCAGGACAA CCCAGCTATG CCCACATCCT CAGGCTCAGA AGGGAATGTC 
AAGCTTTGCT CCCTAGAAGA AGCTCAAAGG ATATGGAAAC AAAAGTCGGC AGAGATTTAT 
CCAATAATGG ACAAGTCAAG CCGCACACGT CTTGCTCTCA TTATCTGCAA TGAAGAATTT 
GACAGTATTC CTAGAAGAAC TGGAGCTGAG GTTGACATCA CAGGCATGAC AATGCTGCTA 
CAAAATCTGG GGTACAGCGT AGATGTGAAA AAAAATCTCA CTGCTTCGGA CATGACTACA 
GAGCTGGAGG CATTTGCACA CCGCCCAGAG CACAAGACCT CTGACAGCAC GTTCCTGGTG 
TTCATGTCTC ATGGTATTCG GGAAGGCATT TGTGGGAAGA AACACTCTGA GCAAGTCCCA 
GATATACTAC AACTCAATGC AATCTTTAAC ATGTTGAATA CCAAGAACTG CCCAAGTTTG 
AAGGACAAAC CGAAGGTGAT CATCATCCAG GCCTGCCGTG GTGACAGCCC TGGTGTGGTG 
TGGTTTAAAG ATTCAGTAGG AGTTTCTGGA AACCTATCTT TACCAACTAC AGAAGAGTTT 
GAGGATGATG CTATTAAGAA AGCCCACATA GAGAAGGATT TTATCGCTTT CTGCTCTTCC 
ACACCAGATA ATGTTTCTTG GAGACATCCC ACAATGGGCT CTGTTTTTAT TGGAAGACTC 
ATTGAACATA TGCAAGAATA TGCCTGTTCC TGTGATGTGG AGGAAATTTT CCGCAAGGTT 
CGATTTTCAT TTGAGCAGCC AGATGGTAGA GCGCAGATGC CCACCACTGA AAGAGTGACT 
TTGACAAGAT GTTTCTACCT CTTCCCAGGA CATTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CASP1 ( NM_001223.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_001214.1 Homo sapiens caspase 1 (CASP1), transcript variant beta, mRNA.

Price & Availability↑

CloneID	OHu20634
Clone ID Related Accession (Same CDS sequence)	NM_001223.5 , NM_001257119.2 , NM_001223.4 , NM_001257119.3
Accession Version	NM_001223.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1152bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-07-01
Organism	Homo sapiens(human)
Product	caspase-1 isoform beta precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AP001153.5, U13697.1, AA505065.1 and KF455483.1. On May 31, 2019 this sequence version replaced NM_001223.4. Transcript Variant: This variant (beta) lacks an in-frame exon in the coding region, compared to variant alpha. Variant beta encodes a protein lacking an internal segment, compared to isoform alpha.Variant beta and variant 7 encode the same protein. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR5189652.155578.1, SRR5189658.159075.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCCGACA AGGTCCTGAA GGAGAAGAGA AAGCTGTTTA TCCGTTCCAT GGGTGAAGGT 
ACAATAAATG GCTTACTGGA TGAATTATTA CAGACAAGGG TGCTGAACAA GGAAGAGATG 
GAGAAAGTAA AACGTGAAAA TGCTACAGTT ATGGATAAGA CCCGAGCTTT GATTGACTCC 
GTTATTCCGA AAGGGGCACA GGCATGCCAA ATTTGCATCA CATACATTTG TGAAGAAGAC 
AGTTACCTGG CAGGGACGCT GGGACTCTCA GCAGCTCCTC AGGCAGTGCA GGACAACCCA 
GCTATGCCCA CATCCTCAGG CTCAGAAGGG AATGTCAAGC TTTGCTCCCT AGAAGAAGCT 
CAAAGGATAT GGAAACAAAA GTCGGCAGAG ATTTATCCAA TAATGGACAA GTCAAGCCGC 
ACACGTCTTG CTCTCATTAT CTGCAATGAA GAATTTGACA GTATTCCTAG AAGAACTGGA 
GCTGAGGTTG ACATCACAGG CATGACAATG CTGCTACAAA ATCTGGGGTA CAGCGTAGAT 
GTGAAAAAAA ATCTCACTGC TTCGGACATG ACTACAGAGC TGGAGGCATT TGCACACCGC 
CCAGAGCACA AGACCTCTGA CAGCACGTTC CTGGTGTTCA TGTCTCATGG TATTCGGGAA 
GGCATTTGTG GGAAGAAACA CTCTGAGCAA GTCCCAGATA TACTACAACT CAATGCAATC 
TTTAACATGT TGAATACCAA GAACTGCCCA AGTTTGAAGG ACAAACCGAA GGTGATCATC 
ATCCAGGCCT GCCGTGGTGA CAGCCCTGGT GTGGTGTGGT TTAAAGATTC AGTAGGAGTT 
TCTGGAAACC TATCTTTACC AACTACAGAA GAGTTTGAGG ATGATGCTAT TAAGAAAGCC 
CACATAGAGA AGGATTTTAT CGCTTTCTGC TCTTCCACAC CAGATAATGT TTCTTGGAGA 
CATCCCACAA TGGGCTCTGT TTTTATTGGA AGACTCATTG AACATATGCA AGAATATGCC 
TGTTCCTGTG ATGTGGAGGA AATTTTCCGC AAGGTTCGAT TTTCATTTGA GCAGCCAGAT 
GGTAGAGCGC AGATGCCCAC CACTGAAAGA GTGACTTTGA CAAGATGTTT CTACCTCTTC 
CCAGGACATT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001214.1
CDS	32..1183
Translation	MADKVLKEKRKLFIRSMGEGTINGLLDELLQTRVLNKEEMEKVKRENATVMDKTRALIDSVIPKGAQACQICITYICEEDSYLAGTLGLSAAPQAVQDNPAMPTSSGSEGNVKLCSLEEAQRIWKQKSAEIYPIMDKSSRTRLALIICNEEFDSIPRRTGAEVDITGMTMLLQNLGYSVDVKKNLTASDMTTELEAFAHRPEHKTSDSTFLVFMSHGIREGICGKKHSEQVPDILQLNAIFNMLNTKNCPSLKDKPKVIIIQACRGDSPGVVWFKDSVGVSGNLSLPTTEEFEDDAIKKAHIEKDFIAFCSSTPDNVSWRHPTMGSVFIGRLIEHMQEYACSCDVEEIFRKVRFSFEQPDGRAQMPTTERVTLTRCFYLFPGH

Target ORF information:

RefSeq Version	NM_001223.5
Organism	Homo sapiens(human)
Definition	Homo sapiens caspase 1 (CASP1), transcript variant beta, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001223.5

ORF Insert Sequence:

ATGGCCGACA AGGTCCTGAA GGAGAAGAGA AAGCTGTTTA TCCGTTCCAT GGGTGAAGGT 
ACAATAAATG GCTTACTGGA TGAATTATTA CAGACAAGGG TGCTGAACAA GGAAGAGATG 
GAGAAAGTAA AACGTGAAAA TGCTACAGTT ATGGATAAGA CCCGAGCTTT GATTGACTCC 
GTTATTCCGA AAGGGGCACA GGCATGCCAA ATTTGCATCA CATACATTTG TGAAGAAGAC 
AGTTACCTGG CAGGGACGCT GGGACTCTCA GCAGCTCCTC AGGCAGTGCA GGACAACCCA 
GCTATGCCCA CATCCTCAGG CTCAGAAGGG AATGTCAAGC TTTGCTCCCT AGAAGAAGCT 
CAAAGGATAT GGAAACAAAA GTCGGCAGAG ATTTATCCAA TAATGGACAA GTCAAGCCGC 
ACACGTCTTG CTCTCATTAT CTGCAATGAA GAATTTGACA GTATTCCTAG AAGAACTGGA 
GCTGAGGTTG ACATCACAGG CATGACAATG CTGCTACAAA ATCTGGGGTA CAGCGTAGAT 
GTGAAAAAAA ATCTCACTGC TTCGGACATG ACTACAGAGC TGGAGGCATT TGCACACCGC 
CCAGAGCACA AGACCTCTGA CAGCACGTTC CTGGTGTTCA TGTCTCATGG TATTCGGGAA 
GGCATTTGTG GGAAGAAACA CTCTGAGCAA GTCCCAGATA TACTACAACT CAATGCAATC 
TTTAACATGT TGAATACCAA GAACTGCCCA AGTTTGAAGG ACAAACCGAA GGTGATCATC 
ATCCAGGCCT GCCGTGGTGA CAGCCCTGGT GTGGTGTGGT TTAAAGATTC AGTAGGAGTT 
TCTGGAAACC TATCTTTACC AACTACAGAA GAGTTTGAGG ATGATGCTAT TAAGAAAGCC 
CACATAGAGA AGGATTTTAT CGCTTTCTGC TCTTCCACAC CAGATAATGT TTCTTGGAGA 
CATCCCACAA TGGGCTCTGT TTTTATTGGA AGACTCATTG AACATATGCA AGAATATGCC 
TGTTCCTGTG ATGTGGAGGA AATTTTCCGC AAGGTTCGAT TTTCATTTGA GCAGCCAGAT 
GGTAGAGCGC AGATGCCCAC CACTGAAAGA GTGACTTTGA CAAGATGTTT CTACCTCTTC 
CCAGGACATT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CASP1 ( NM_001257119.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001244048.1 Homo sapiens caspase 1 (CASP1), transcript variant 7, mRNA.

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CloneID	OHu20634
Clone ID Related Accession (Same CDS sequence)	NM_001223.5 , NM_001257119.2 , NM_001223.4 , NM_001257119.3
Accession Version	NM_001257119.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1152bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-01-12
Organism	Homo sapiens(human)
Product	caspase-1 isoform beta precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AP001153.5, AK290122.1, KF455483.1 and AA737419.1. On Jan 17, 2014 this sequence version replaced NM_001257119.1. Transcript Variant: This variant (7) lacks an alternate in-frame exon and differs in the 3' UTR compared to variant alpha. Variant beta and variant 7 encode the same protein. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803613.271849.1, SRR1660803.39445.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCCGACA AGGTCCTGAA GGAGAAGAGA AAGCTGTTTA TCCGTTCCAT GGGTGAAGGT 
ACAATAAATG GCTTACTGGA TGAATTATTA CAGACAAGGG TGCTGAACAA GGAAGAGATG 
GAGAAAGTAA AACGTGAAAA TGCTACAGTT ATGGATAAGA CCCGAGCTTT GATTGACTCC 
GTTATTCCGA AAGGGGCACA GGCATGCCAA ATTTGCATCA CATACATTTG TGAAGAAGAC 
AGTTACCTGG CAGGGACGCT GGGACTCTCA GCAGCTCCTC AGGCAGTGCA GGACAACCCA 
GCTATGCCCA CATCCTCAGG CTCAGAAGGG AATGTCAAGC TTTGCTCCCT AGAAGAAGCT 
CAAAGGATAT GGAAACAAAA GTCGGCAGAG ATTTATCCAA TAATGGACAA GTCAAGCCGC 
ACACGTCTTG CTCTCATTAT CTGCAATGAA GAATTTGACA GTATTCCTAG AAGAACTGGA 
GCTGAGGTTG ACATCACAGG CATGACAATG CTGCTACAAA ATCTGGGGTA CAGCGTAGAT 
GTGAAAAAAA ATCTCACTGC TTCGGACATG ACTACAGAGC TGGAGGCATT TGCACACCGC 
CCAGAGCACA AGACCTCTGA CAGCACGTTC CTGGTGTTCA TGTCTCATGG TATTCGGGAA 
GGCATTTGTG GGAAGAAACA CTCTGAGCAA GTCCCAGATA TACTACAACT CAATGCAATC 
TTTAACATGT TGAATACCAA GAACTGCCCA AGTTTGAAGG ACAAACCGAA GGTGATCATC 
ATCCAGGCCT GCCGTGGTGA CAGCCCTGGT GTGGTGTGGT TTAAAGATTC AGTAGGAGTT 
TCTGGAAACC TATCTTTACC AACTACAGAA GAGTTTGAGG ATGATGCTAT TAAGAAAGCC 
CACATAGAGA AGGATTTTAT CGCTTTCTGC TCTTCCACAC CAGATAATGT TTCTTGGAGA 
CATCCCACAA TGGGCTCTGT TTTTATTGGA AGACTCATTG AACATATGCA AGAATATGCC 
TGTTCCTGTG ATGTGGAGGA AATTTTCCGC AAGGTTCGAT TTTCATTTGA GCAGCCAGAT 
GGTAGAGCGC AGATGCCCAC CACTGAAAGA GTGACTTTGA CAAGATGTTT CTACCTCTTC 
CCAGGACATT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001244048.1
CDS	45..1196
Translation	MADKVLKEKRKLFIRSMGEGTINGLLDELLQTRVLNKEEMEKVKRENATVMDKTRALIDSVIPKGAQACQICITYICEEDSYLAGTLGLSAAPQAVQDNPAMPTSSGSEGNVKLCSLEEAQRIWKQKSAEIYPIMDKSSRTRLALIICNEEFDSIPRRTGAEVDITGMTMLLQNLGYSVDVKKNLTASDMTTELEAFAHRPEHKTSDSTFLVFMSHGIREGICGKKHSEQVPDILQLNAIFNMLNTKNCPSLKDKPKVIIIQACRGDSPGVVWFKDSVGVSGNLSLPTTEEFEDDAIKKAHIEKDFIAFCSSTPDNVSWRHPTMGSVFIGRLIEHMQEYACSCDVEEIFRKVRFSFEQPDGRAQMPTTERVTLTRCFYLFPGH

Target ORF information:

RefSeq Version	NM_001257119.2
Organism	Homo sapiens(human)
Definition	Homo sapiens caspase 1 (CASP1), transcript variant 7, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001257119.2

ORF Insert Sequence:

ATGGCCGACA AGGTCCTGAA GGAGAAGAGA AAGCTGTTTA TCCGTTCCAT GGGTGAAGGT 
ACAATAAATG GCTTACTGGA TGAATTATTA CAGACAAGGG TGCTGAACAA GGAAGAGATG 
GAGAAAGTAA AACGTGAAAA TGCTACAGTT ATGGATAAGA CCCGAGCTTT GATTGACTCC 
GTTATTCCGA AAGGGGCACA GGCATGCCAA ATTTGCATCA CATACATTTG TGAAGAAGAC 
AGTTACCTGG CAGGGACGCT GGGACTCTCA GCAGCTCCTC AGGCAGTGCA GGACAACCCA 
GCTATGCCCA CATCCTCAGG CTCAGAAGGG AATGTCAAGC TTTGCTCCCT AGAAGAAGCT 
CAAAGGATAT GGAAACAAAA GTCGGCAGAG ATTTATCCAA TAATGGACAA GTCAAGCCGC 
ACACGTCTTG CTCTCATTAT CTGCAATGAA GAATTTGACA GTATTCCTAG AAGAACTGGA 
GCTGAGGTTG ACATCACAGG CATGACAATG CTGCTACAAA ATCTGGGGTA CAGCGTAGAT 
GTGAAAAAAA ATCTCACTGC TTCGGACATG ACTACAGAGC TGGAGGCATT TGCACACCGC 
CCAGAGCACA AGACCTCTGA CAGCACGTTC CTGGTGTTCA TGTCTCATGG TATTCGGGAA 
GGCATTTGTG GGAAGAAACA CTCTGAGCAA GTCCCAGATA TACTACAACT CAATGCAATC 
TTTAACATGT TGAATACCAA GAACTGCCCA AGTTTGAAGG ACAAACCGAA GGTGATCATC 
ATCCAGGCCT GCCGTGGTGA CAGCCCTGGT GTGGTGTGGT TTAAAGATTC AGTAGGAGTT 
TCTGGAAACC TATCTTTACC AACTACAGAA GAGTTTGAGG ATGATGCTAT TAAGAAAGCC 
CACATAGAGA AGGATTTTAT CGCTTTCTGC TCTTCCACAC CAGATAATGT TTCTTGGAGA 
CATCCCACAA TGGGCTCTGT TTTTATTGGA AGACTCATTG AACATATGCA AGAATATGCC 
TGTTCCTGTG ATGTGGAGGA AATTTTCCGC AAGGTTCGAT TTTCATTTGA GCAGCCAGAT 
GGTAGAGCGC AGATGCCCAC CACTGAAAGA GTGACTTTGA CAAGATGTTT CTACCTCTTC 
CCAGGACATT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CASP1 ( NM_001223.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_001214.1 Homo sapiens caspase 1 (CASP1), transcript variant beta, mRNA.

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CloneID	OHu20634
Clone ID Related Accession (Same CDS sequence)	NM_001223.5 , NM_001257119.2 , NM_001223.4 , NM_001257119.3
Accession Version	NM_001223.4	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1152bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-01-12
Organism	Homo sapiens(human)
Product	caspase-1 isoform beta precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AP001153.5, U13697.1 and AA505065.1. On Mar 14, 2012 this sequence version replaced NM_001223.3. Transcript Variant: This variant (beta) lacks an in-frame exon in the coding region, compared to variant alpha. Variant beta encodes a protein lacking an internal segment, compared to isoform alpha.Variant beta and variant 7 encode the same protein. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR5189652.155578.1, SRR5189658.159075.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCCGACA AGGTCCTGAA GGAGAAGAGA AAGCTGTTTA TCCGTTCCAT GGGTGAAGGT 
ACAATAAATG GCTTACTGGA TGAATTATTA CAGACAAGGG TGCTGAACAA GGAAGAGATG 
GAGAAAGTAA AACGTGAAAA TGCTACAGTT ATGGATAAGA CCCGAGCTTT GATTGACTCC 
GTTATTCCGA AAGGGGCACA GGCATGCCAA ATTTGCATCA CATACATTTG TGAAGAAGAC 
AGTTACCTGG CAGGGACGCT GGGACTCTCA GCAGCTCCTC AGGCAGTGCA GGACAACCCA 
GCTATGCCCA CATCCTCAGG CTCAGAAGGG AATGTCAAGC TTTGCTCCCT AGAAGAAGCT 
CAAAGGATAT GGAAACAAAA GTCGGCAGAG ATTTATCCAA TAATGGACAA GTCAAGCCGC 
ACACGTCTTG CTCTCATTAT CTGCAATGAA GAATTTGACA GTATTCCTAG AAGAACTGGA 
GCTGAGGTTG ACATCACAGG CATGACAATG CTGCTACAAA ATCTGGGGTA CAGCGTAGAT 
GTGAAAAAAA ATCTCACTGC TTCGGACATG ACTACAGAGC TGGAGGCATT TGCACACCGC 
CCAGAGCACA AGACCTCTGA CAGCACGTTC CTGGTGTTCA TGTCTCATGG TATTCGGGAA 
GGCATTTGTG GGAAGAAACA CTCTGAGCAA GTCCCAGATA TACTACAACT CAATGCAATC 
TTTAACATGT TGAATACCAA GAACTGCCCA AGTTTGAAGG ACAAACCGAA GGTGATCATC 
ATCCAGGCCT GCCGTGGTGA CAGCCCTGGT GTGGTGTGGT TTAAAGATTC AGTAGGAGTT 
TCTGGAAACC TATCTTTACC AACTACAGAA GAGTTTGAGG ATGATGCTAT TAAGAAAGCC 
CACATAGAGA AGGATTTTAT CGCTTTCTGC TCTTCCACAC CAGATAATGT TTCTTGGAGA 
CATCCCACAA TGGGCTCTGT TTTTATTGGA AGACTCATTG AACATATGCA AGAATATGCC 
TGTTCCTGTG ATGTGGAGGA AATTTTCCGC AAGGTTCGAT TTTCATTTGA GCAGCCAGAT 
GGTAGAGCGC AGATGCCCAC CACTGAAAGA GTGACTTTGA CAAGATGTTT CTACCTCTTC 
CCAGGACATT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001214.1
CDS	45..1196
Translation	MADKVLKEKRKLFIRSMGEGTINGLLDELLQTRVLNKEEMEKVKRENATVMDKTRALIDSVIPKGAQACQICITYICEEDSYLAGTLGLSAAPQAVQDNPAMPTSSGSEGNVKLCSLEEAQRIWKQKSAEIYPIMDKSSRTRLALIICNEEFDSIPRRTGAEVDITGMTMLLQNLGYSVDVKKNLTASDMTTELEAFAHRPEHKTSDSTFLVFMSHGIREGICGKKHSEQVPDILQLNAIFNMLNTKNCPSLKDKPKVIIIQACRGDSPGVVWFKDSVGVSGNLSLPTTEEFEDDAIKKAHIEKDFIAFCSSTPDNVSWRHPTMGSVFIGRLIEHMQEYACSCDVEEIFRKVRFSFEQPDGRAQMPTTERVTLTRCFYLFPGH

Target ORF information:

RefSeq Version	NM_001223.4
Organism	Homo sapiens(human)
Definition	Homo sapiens caspase 1 (CASP1), transcript variant beta, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001223.4

ORF Insert Sequence:

ATGGCCGACA AGGTCCTGAA GGAGAAGAGA AAGCTGTTTA TCCGTTCCAT GGGTGAAGGT 
ACAATAAATG GCTTACTGGA TGAATTATTA CAGACAAGGG TGCTGAACAA GGAAGAGATG 
GAGAAAGTAA AACGTGAAAA TGCTACAGTT ATGGATAAGA CCCGAGCTTT GATTGACTCC 
GTTATTCCGA AAGGGGCACA GGCATGCCAA ATTTGCATCA CATACATTTG TGAAGAAGAC 
AGTTACCTGG CAGGGACGCT GGGACTCTCA GCAGCTCCTC AGGCAGTGCA GGACAACCCA 
GCTATGCCCA CATCCTCAGG CTCAGAAGGG AATGTCAAGC TTTGCTCCCT AGAAGAAGCT 
CAAAGGATAT GGAAACAAAA GTCGGCAGAG ATTTATCCAA TAATGGACAA GTCAAGCCGC 
ACACGTCTTG CTCTCATTAT CTGCAATGAA GAATTTGACA GTATTCCTAG AAGAACTGGA 
GCTGAGGTTG ACATCACAGG CATGACAATG CTGCTACAAA ATCTGGGGTA CAGCGTAGAT 
GTGAAAAAAA ATCTCACTGC TTCGGACATG ACTACAGAGC TGGAGGCATT TGCACACCGC 
CCAGAGCACA AGACCTCTGA CAGCACGTTC CTGGTGTTCA TGTCTCATGG TATTCGGGAA 
GGCATTTGTG GGAAGAAACA CTCTGAGCAA GTCCCAGATA TACTACAACT CAATGCAATC 
TTTAACATGT TGAATACCAA GAACTGCCCA AGTTTGAAGG ACAAACCGAA GGTGATCATC 
ATCCAGGCCT GCCGTGGTGA CAGCCCTGGT GTGGTGTGGT TTAAAGATTC AGTAGGAGTT 
TCTGGAAACC TATCTTTACC AACTACAGAA GAGTTTGAGG ATGATGCTAT TAAGAAAGCC 
CACATAGAGA AGGATTTTAT CGCTTTCTGC TCTTCCACAC CAGATAATGT TTCTTGGAGA 
CATCCCACAA TGGGCTCTGT TTTTATTGGA AGACTCATTG AACATATGCA AGAATATGCC 
TGTTCCTGTG ATGTGGAGGA AATTTTCCGC AAGGTTCGAT TTTCATTTGA GCAGCCAGAT 
GGTAGAGCGC AGATGCCCAC CACTGAAAGA GTGACTTTGA CAAGATGTTT CTACCTCTTC 
CCAGGACATT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CASP1 ( NM_001257119.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_001244048.1 Homo sapiens caspase 1 (CASP1), transcript variant 7, mRNA.

Price & Availability↑

CloneID	OHu20634
Clone ID Related Accession (Same CDS sequence)	NM_001223.5 , NM_001257119.2 , NM_001223.4 , NM_001257119.3
Accession Version	NM_001257119.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1152bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-07-01
Organism	Homo sapiens(human)
Product	caspase-1 isoform beta precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK290122.1, AP001153.5, KF455483.1 and AA737419.1. On May 31, 2019 this sequence version replaced NM_001257119.2. Transcript Variant: This variant (7) lacks an alternate in-frame exon and differs in the 3' UTR compared to variant alpha. Variant beta and variant 7 encode the same protein. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR7346977.156134.1, SRR1660803.39445.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCCGACA AGGTCCTGAA GGAGAAGAGA AAGCTGTTTA TCCGTTCCAT GGGTGAAGGT 
ACAATAAATG GCTTACTGGA TGAATTATTA CAGACAAGGG TGCTGAACAA GGAAGAGATG 
GAGAAAGTAA AACGTGAAAA TGCTACAGTT ATGGATAAGA CCCGAGCTTT GATTGACTCC 
GTTATTCCGA AAGGGGCACA GGCATGCCAA ATTTGCATCA CATACATTTG TGAAGAAGAC 
AGTTACCTGG CAGGGACGCT GGGACTCTCA GCAGCTCCTC AGGCAGTGCA GGACAACCCA 
GCTATGCCCA CATCCTCAGG CTCAGAAGGG AATGTCAAGC TTTGCTCCCT AGAAGAAGCT 
CAAAGGATAT GGAAACAAAA GTCGGCAGAG ATTTATCCAA TAATGGACAA GTCAAGCCGC 
ACACGTCTTG CTCTCATTAT CTGCAATGAA GAATTTGACA GTATTCCTAG AAGAACTGGA 
GCTGAGGTTG ACATCACAGG CATGACAATG CTGCTACAAA ATCTGGGGTA CAGCGTAGAT 
GTGAAAAAAA ATCTCACTGC TTCGGACATG ACTACAGAGC TGGAGGCATT TGCACACCGC 
CCAGAGCACA AGACCTCTGA CAGCACGTTC CTGGTGTTCA TGTCTCATGG TATTCGGGAA 
GGCATTTGTG GGAAGAAACA CTCTGAGCAA GTCCCAGATA TACTACAACT CAATGCAATC 
TTTAACATGT TGAATACCAA GAACTGCCCA AGTTTGAAGG ACAAACCGAA GGTGATCATC 
ATCCAGGCCT GCCGTGGTGA CAGCCCTGGT GTGGTGTGGT TTAAAGATTC AGTAGGAGTT 
TCTGGAAACC TATCTTTACC AACTACAGAA GAGTTTGAGG ATGATGCTAT TAAGAAAGCC 
CACATAGAGA AGGATTTTAT CGCTTTCTGC TCTTCCACAC CAGATAATGT TTCTTGGAGA 
CATCCCACAA TGGGCTCTGT TTTTATTGGA AGACTCATTG AACATATGCA AGAATATGCC 
TGTTCCTGTG ATGTGGAGGA AATTTTCCGC AAGGTTCGAT TTTCATTTGA GCAGCCAGAT 
GGTAGAGCGC AGATGCCCAC CACTGAAAGA GTGACTTTGA CAAGATGTTT CTACCTCTTC 
CCAGGACATT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001244048.1
CDS	32..1183
Translation	MADKVLKEKRKLFIRSMGEGTINGLLDELLQTRVLNKEEMEKVKRENATVMDKTRALIDSVIPKGAQACQICITYICEEDSYLAGTLGLSAAPQAVQDNPAMPTSSGSEGNVKLCSLEEAQRIWKQKSAEIYPIMDKSSRTRLALIICNEEFDSIPRRTGAEVDITGMTMLLQNLGYSVDVKKNLTASDMTTELEAFAHRPEHKTSDSTFLVFMSHGIREGICGKKHSEQVPDILQLNAIFNMLNTKNCPSLKDKPKVIIIQACRGDSPGVVWFKDSVGVSGNLSLPTTEEFEDDAIKKAHIEKDFIAFCSSTPDNVSWRHPTMGSVFIGRLIEHMQEYACSCDVEEIFRKVRFSFEQPDGRAQMPTTERVTLTRCFYLFPGH

Target ORF information:

RefSeq Version	NM_001257119.3
Organism	Homo sapiens(human)
Definition	Homo sapiens caspase 1 (CASP1), transcript variant 7, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001257119.3

ORF Insert Sequence:

ATGGCCGACA AGGTCCTGAA GGAGAAGAGA AAGCTGTTTA TCCGTTCCAT GGGTGAAGGT 
ACAATAAATG GCTTACTGGA TGAATTATTA CAGACAAGGG TGCTGAACAA GGAAGAGATG 
GAGAAAGTAA AACGTGAAAA TGCTACAGTT ATGGATAAGA CCCGAGCTTT GATTGACTCC 
GTTATTCCGA AAGGGGCACA GGCATGCCAA ATTTGCATCA CATACATTTG TGAAGAAGAC 
AGTTACCTGG CAGGGACGCT GGGACTCTCA GCAGCTCCTC AGGCAGTGCA GGACAACCCA 
GCTATGCCCA CATCCTCAGG CTCAGAAGGG AATGTCAAGC TTTGCTCCCT AGAAGAAGCT 
CAAAGGATAT GGAAACAAAA GTCGGCAGAG ATTTATCCAA TAATGGACAA GTCAAGCCGC 
ACACGTCTTG CTCTCATTAT CTGCAATGAA GAATTTGACA GTATTCCTAG AAGAACTGGA 
GCTGAGGTTG ACATCACAGG CATGACAATG CTGCTACAAA ATCTGGGGTA CAGCGTAGAT 
GTGAAAAAAA ATCTCACTGC TTCGGACATG ACTACAGAGC TGGAGGCATT TGCACACCGC 
CCAGAGCACA AGACCTCTGA CAGCACGTTC CTGGTGTTCA TGTCTCATGG TATTCGGGAA 
GGCATTTGTG GGAAGAAACA CTCTGAGCAA GTCCCAGATA TACTACAACT CAATGCAATC 
TTTAACATGT TGAATACCAA GAACTGCCCA AGTTTGAAGG ACAAACCGAA GGTGATCATC 
ATCCAGGCCT GCCGTGGTGA CAGCCCTGGT GTGGTGTGGT TTAAAGATTC AGTAGGAGTT 
TCTGGAAACC TATCTTTACC AACTACAGAA GAGTTTGAGG ATGATGCTAT TAAGAAAGCC 
CACATAGAGA AGGATTTTAT CGCTTTCTGC TCTTCCACAC CAGATAATGT TTCTTGGAGA 
CATCCCACAA TGGGCTCTGT TTTTATTGGA AGACTCATTG AACATATGCA AGAATATGCC 
TGTTCCTGTG ATGTGGAGGA AATTTTCCGC AAGGTTCGAT TTTCATTTGA GCAGCCAGAT 
GGTAGAGCGC AGATGCCCAC CACTGAAAGA GTGACTTTGA CAAGATGTTT CTACCTCTTC 
CCAGGACATT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CASP1 ( NM_033294.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_150636.1 Homo sapiens caspase 1 (CASP1), transcript variant delta, mRNA.

Price & Availability↑

CloneID	OHu21151
Clone ID Related Accession (Same CDS sequence)	NM_033294.3
Accession Version	NM_033294.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 792bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-07-01
Organism	Homo sapiens(human)
Product	caspase-1 isoform delta
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AP001153.5, U13699.1 and AA761907.1. On Mar 14, 2012 this sequence version replaced NM_033294.2. Transcript Variant: This variant (delta) has multiple differences in the coding region but the translation remains in frame, compared to variant alpha. Variant delta encodes a protein lacking two internal segments, compared to the isoform alpha. Isoform delta lacks apoptosis-inducing activity. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCCGACA AGGTCCTGAA GGAGAAGAGA AAGCTGTTTA TCCGTTCCAT GGGTGAAGCT 
CCTCAGGCAG TGCAGGACAA CCCAGCTATG CCCACATCCT CAGGCTCAGA AGGGAATGTC 
AAGCTTTGCT CCCTAGAAGA AGCTCAAAGG ATATGGAAAC AAAAGTCGGC AGAGATTTAT 
CCAATAATGG ACAAGTCAAG CCGCACACGT CTTGCTCTCA TTATCTGCAA TGAAGAATTT 
GACAGTATTC CTAGAAGAAC TGGAGCTGAG GTTGACATCA CAGGCATGAC AATGCTGCTA 
CAAAATCTGG GGTACAGCGT AGATGTGAAA AAAAATCTCA CTGCTTCGGA CATGACTACA 
GAGCTGGAGG CATTTGCACA CCGCCCAGAG CACAAGACCT CTGACAGCAC GTTCCTGGTG 
TTCATGTCTC ATGGTATTCG GGAAGGCATT TGTGGGAAGA AACACTCTGA GCAAGTCCCA 
GATATACTAC AACTCAATGC AATCTTTAAC ATGTTGAATA CCAAGAACTG CCCAAGTTTG 
AAGGACAAAC CGAAGGTGAT CATCATCCAG GCCTGCCGTG GTGATAATGT TTCTTGGAGA 
CATCCCACAA TGGGCTCTGT TTTTATTGGA AGACTCATTG AACATATGCA AGAATATGCC 
TGTTCCTGTG ATGTGGAGGA AATTTTCCGC AAGGTTCGAT TTTCATTTGA GCAGCCAGAT 
GGTAGAGCGC AGATGCCCAC CACTGAAAGA GTGACTTTGA CAAGATGTTT CTACCTCTTC 
CCAGGACATT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_150636.1
CDS	45..836
Translation	MADKVLKEKRKLFIRSMGEAPQAVQDNPAMPTSSGSEGNVKLCSLEEAQRIWKQKSAEIYPIMDKSSRTRLALIICNEEFDSIPRRTGAEVDITGMTMLLQNLGYSVDVKKNLTASDMTTELEAFAHRPEHKTSDSTFLVFMSHGIREGICGKKHSEQVPDILQLNAIFNMLNTKNCPSLKDKPKVIIIQACRGDNVSWRHPTMGSVFIGRLIEHMQEYACSCDVEEIFRKVRFSFEQPDGRAQMPTTERVTLTRCFYLFPGH

Target ORF information:

RefSeq Version	NM_033294.3
Organism	Homo sapiens(human)
Definition	Homo sapiens caspase 1 (CASP1), transcript variant delta, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_033294.3

ORF Insert Sequence:

ATGGCCGACA AGGTCCTGAA GGAGAAGAGA AAGCTGTTTA TCCGTTCCAT GGGTGAAGCT 
CCTCAGGCAG TGCAGGACAA CCCAGCTATG CCCACATCCT CAGGCTCAGA AGGGAATGTC 
AAGCTTTGCT CCCTAGAAGA AGCTCAAAGG ATATGGAAAC AAAAGTCGGC AGAGATTTAT 
CCAATAATGG ACAAGTCAAG CCGCACACGT CTTGCTCTCA TTATCTGCAA TGAAGAATTT 
GACAGTATTC CTAGAAGAAC TGGAGCTGAG GTTGACATCA CAGGCATGAC AATGCTGCTA 
CAAAATCTGG GGTACAGCGT AGATGTGAAA AAAAATCTCA CTGCTTCGGA CATGACTACA 
GAGCTGGAGG CATTTGCACA CCGCCCAGAG CACAAGACCT CTGACAGCAC GTTCCTGGTG 
TTCATGTCTC ATGGTATTCG GGAAGGCATT TGTGGGAAGA AACACTCTGA GCAAGTCCCA 
GATATACTAC AACTCAATGC AATCTTTAAC ATGTTGAATA CCAAGAACTG CCCAAGTTTG 
AAGGACAAAC CGAAGGTGAT CATCATCCAG GCCTGCCGTG GTGATAATGT TTCTTGGAGA 
CATCCCACAA TGGGCTCTGT TTTTATTGGA AGACTCATTG AACATATGCA AGAATATGCC 
TGTTCCTGTG ATGTGGAGGA AATTTTCCGC AAGGTTCGAT TTTCATTTGA GCAGCCAGAT 
GGTAGAGCGC AGATGCCCAC CACTGAAAGA GTGACTTTGA CAAGATGTTT CTACCTCTTC 
CCAGGACATT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CASP1 ( NM_033295.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_150637.1 Homo sapiens caspase 1 (CASP1), transcript variant epsilon, mRNA.

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CloneID	OHu21774
Clone ID Related Accession (Same CDS sequence)	NM_033295.3
Accession Version	NM_033295.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 267bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-07-01
Organism	Homo sapiens(human)
Product	caspase-1 isoform epsilon
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AP001153.5, U13700.1 and AA761907.1. On Mar 14, 2012 this sequence version replaced NM_033295.2. Transcript Variant: This variant (epsilon) has multiple differences in the coding region but the translation remains in frame, compared to variant alpha. Variant epsilon encodes a protein lacking an internal segment, compared to isoform alpha. Isoform epsilon lacks apoptosis-inducing activity. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCCGACA AGGTCCTGAA GGAGAAGAGA AAGCTGTTTA TCCGTTCCAT GGGTGAAGAT 
AATGTTTCTT GGAGACATCC CACAATGGGC TCTGTTTTTA TTGGAAGACT CATTGAACAT 
ATGCAAGAAT ATGCCTGTTC CTGTGATGTG GAGGAAATTT TCCGCAAGGT TCGATTTTCA 
TTTGAGCAGC CAGATGGTAG AGCGCAGATG CCCACCACTG AAAGAGTGAC TTTGACAAGA 
TGTTTCTACC TCTTCCCAGG ACATTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_150637.1
CDS	45..311
Translation	MADKVLKEKRKLFIRSMGEDNVSWRHPTMGSVFIGRLIEHMQEYACSCDVEEIFRKVRFSFEQPDGRAQMPTTERVTLTRCFYLFPGH

Target ORF information:

RefSeq Version	NM_033295.3
Organism	Homo sapiens(human)
Definition	Homo sapiens caspase 1 (CASP1), transcript variant epsilon, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_033295.3

ORF Insert Sequence:

ATGGCCGACA AGGTCCTGAA GGAGAAGAGA AAGCTGTTTA TCCGTTCCAT GGGTGAAGAT 
AATGTTTCTT GGAGACATCC CACAATGGGC TCTGTTTTTA TTGGAAGACT CATTGAACAT 
ATGCAAGAAT ATGCCTGTTC CTGTGATGTG GAGGAAATTT TCCGCAAGGT TCGATTTTCA 
TTTGAGCAGC CAGATGGTAG AGCGCAGATG CCCACCACTG AAAGAGTGAC TTTGACAAGA 
TGTTTCTACC TCTTCCCAGG ACATTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CASP1 ( XM_017018396.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016873885.1 Homo sapiens caspase 1 (CASP1), transcript variant X4, mRNA.

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CloneID	OHu92572
Clone ID Related Accession (Same CDS sequence)	XM_017018396.1
Accession Version	XM_017018396.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1125bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	caspase-1 isoform X3
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000011.10) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGACAAGGG TGCTGAACAA GGAAGAGATG GAGAAAGTAA AACGTGAAAA TGCTACAGTT 
ATGGATAAGA CCCGAGCTTT GATTGACTCC GTTATTCCGA AAGGGGCACA GGCATGCCAA 
ATTTGCATCA CATACATTTG TGAAGAAGAC AGTTACCTGG CAGGGACGCT GGGACTCTCA 
GCAGATCAAA CATCTGGAAA TTACCTTAAT ATGCAAGACT CTCAAGGAGT ACTTTCTTCC 
TTTCCAGCTC CTCAGGCAGT GCAGGACAAC CCAGCTATGC CCACATCCTC AGGCTCAGAA 
GGGAATGTCA AGCTTTGCTC CCTAGAAGAA GCTCAAAGGA TATGGAAACA AAAGTCGGCA 
GAGATTTATC CAATAATGGA CAAGTCAAGC CGCACACGTC TTGCTCTCAT TATCTGCAAT 
GAAGAATTTG ACAGTATTCC TAGAAGAACT GGAGCTGAGG TTGACATCAC AGGCATGACA 
ATGCTGCTAC AAAATCTGGG GTACAGCGTA GATGTGAAAA AAAATCTCAC TGCTTCGGAC 
ATGACTACAG AGCTGGAGGC ATTTGCACAC CGCCCAGAGC ACAAGACCTC TGACAGCACG 
TTCCTGGTGT TCATGTCTCA TGGTATTCGG GAAGGCATTT GTGGGAAGAA ACACTCTGAG 
CAAGTCCCAG ATATACTACA ACTCAATGCA ATCTTTAACA TGTTGAATAC CAAGAACTGC 
CCAAGTTTGA AGGACAAACC GAAGGTGATC ATCATCCAGG CCTGCCGTGG TGACAGCCCT 
GGTGTGGTGT GGTTTAAAGA TTCAGTAGGA GTTTCTGGAA ACCTATCTTT ACCAACTACA 
GAAGAGTTTG AGGATGATGC TATTAAGAAA GCCCACATAG AGAAGGATTT TATCGCTTTC 
TGCTCTTCCA CACCAGATAA TGTTTCTTGG AGACATCCCA CAATGGGCTC TGTTTTTATT 
GGAAGACTCA TTGAACATAT GCAAGAATAT GCCTGTTCCT GTGATGTGGA GGAAATTTTC 
CGCAAGGTTC GATTTTCATT TGAGCAGCCA GATGGTAGAG CGCAGATGCC CACCACTGAA 
AGAGTGACTT TGACAAGATG TTTCTACCTC TTCCCAGGAC ATTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016873885.1
CDS	392..1516
Translation	MTRVLNKEEMEKVKRENATVMDKTRALIDSVIPKGAQACQICITYICEEDSYLAGTLGLSADQTSGNYLNMQDSQGVLSSFPAPQAVQDNPAMPTSSGSEGNVKLCSLEEAQRIWKQKSAEIYPIMDKSSRTRLALIICNEEFDSIPRRTGAEVDITGMTMLLQNLGYSVDVKKNLTASDMTTELEAFAHRPEHKTSDSTFLVFMSHGIREGICGKKHSEQVPDILQLNAIFNMLNTKNCPSLKDKPKVIIIQACRGDSPGVVWFKDSVGVSGNLSLPTTEEFEDDAIKKAHIEKDFIAFCSSTPDNVSWRHPTMGSVFIGRLIEHMQEYACSCDVEEIFRKVRFSFEQPDGRAQMPTTERVTLTRCFYLFPGH

Target ORF information:

RefSeq Version	XM_017018396.1
Organism	Homo sapiens(human)
Definition	Homo sapiens caspase 1 (CASP1), transcript variant X4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017018396.1

ORF Insert Sequence:

ATGACAAGGG TGCTGAACAA GGAAGAGATG GAGAAAGTAA AACGTGAAAA TGCTACAGTT 
ATGGATAAGA CCCGAGCTTT GATTGACTCC GTTATTCCGA AAGGGGCACA GGCATGCCAA 
ATTTGCATCA CATACATTTG TGAAGAAGAC AGTTACCTGG CAGGGACGCT GGGACTCTCA 
GCAGATCAAA CATCTGGAAA TTACCTTAAT ATGCAAGACT CTCAAGGAGT ACTTTCTTCC 
TTTCCAGCTC CTCAGGCAGT GCAGGACAAC CCAGCTATGC CCACATCCTC AGGCTCAGAA 
GGGAATGTCA AGCTTTGCTC CCTAGAAGAA GCTCAAAGGA TATGGAAACA AAAGTCGGCA 
GAGATTTATC CAATAATGGA CAAGTCAAGC CGCACACGTC TTGCTCTCAT TATCTGCAAT 
GAAGAATTTG ACAGTATTCC TAGAAGAACT GGAGCTGAGG TTGACATCAC AGGCATGACA 
ATGCTGCTAC AAAATCTGGG GTACAGCGTA GATGTGAAAA AAAATCTCAC TGCTTCGGAC 
ATGACTACAG AGCTGGAGGC ATTTGCACAC CGCCCAGAGC ACAAGACCTC TGACAGCACG 
TTCCTGGTGT TCATGTCTCA TGGTATTCGG GAAGGCATTT GTGGGAAGAA ACACTCTGAG 
CAAGTCCCAG ATATACTACA ACTCAATGCA ATCTTTAACA TGTTGAATAC CAAGAACTGC 
CCAAGTTTGA AGGACAAACC GAAGGTGATC ATCATCCAGG CCTGCCGTGG TGACAGCCCT 
GGTGTGGTGT GGTTTAAAGA TTCAGTAGGA GTTTCTGGAA ACCTATCTTT ACCAACTACA 
GAAGAGTTTG AGGATGATGC TATTAAGAAA GCCCACATAG AGAAGGATTT TATCGCTTTC 
TGCTCTTCCA CACCAGATAA TGTTTCTTGG AGACATCCCA CAATGGGCTC TGTTTTTATT 
GGAAGACTCA TTGAACATAT GCAAGAATAT GCCTGTTCCT GTGATGTGGA GGAAATTTTC 
CGCAAGGTTC GATTTTCATT TGAGCAGCCA GATGGTAGAG CGCAGATGCC CACCACTGAA 
AGAGTGACTT TGACAAGATG TTTCTACCTC TTCCCAGGAC ATTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CASP1 ( XM_017018394.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016873883.1 Homo sapiens caspase 1 (CASP1), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu92570
Clone ID Related Accession (Same CDS sequence)	XM_017018394.1 , XM_017018393.1
Accession Version	XM_017018394.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1206bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	caspase-1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000011.10) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTACAGGC CCTGCCAAAA AGGAAGGCGA AGCATACTTT CAGTTTCAGT CACACAAGAA 
GGGAGGAGAG AAAAGCCATG GCCGACAAGG GTGCTGAACA AGGAAGAGAT GGAGAAAGTA 
AAACGTGAAA ATGCTACAGT TATGGATAAG ACCCGAGCTT TGATTGACTC CGTTATTCCG 
AAAGGGGCAC AGGCATGCCA AATTTGCATC ACATACATTT GTGAAGAAGA CAGTTACCTG 
GCAGGGACGC TGGGACTCTC AGCAGATCAA ACATCTGGAA ATTACCTTAA TATGCAAGAC 
TCTCAAGGAG TACTTTCTTC CTTTCCAGCT CCTCAGGCAG TGCAGGACAA CCCAGCTATG 
CCCACATCCT CAGGCTCAGA AGGGAATGTC AAGCTTTGCT CCCTAGAAGA AGCTCAAAGG 
ATATGGAAAC AAAAGTCGGC AGAGATTTAT CCAATAATGG ACAAGTCAAG CCGCACACGT 
CTTGCTCTCA TTATCTGCAA TGAAGAATTT GACAGTATTC CTAGAAGAAC TGGAGCTGAG 
GTTGACATCA CAGGCATGAC AATGCTGCTA CAAAATCTGG GGTACAGCGT AGATGTGAAA 
AAAAATCTCA CTGCTTCGGA CATGACTACA GAGCTGGAGG CATTTGCACA CCGCCCAGAG 
CACAAGACCT CTGACAGCAC GTTCCTGGTG TTCATGTCTC ATGGTATTCG GGAAGGCATT 
TGTGGGAAGA AACACTCTGA GCAAGTCCCA GATATACTAC AACTCAATGC AATCTTTAAC 
ATGTTGAATA CCAAGAACTG CCCAAGTTTG AAGGACAAAC CGAAGGTGAT CATCATCCAG 
GCCTGCCGTG GTGACAGCCC TGGTGTGGTG TGGTTTAAAG ATTCAGTAGG AGTTTCTGGA 
AACCTATCTT TACCAACTAC AGAAGAGTTT GAGGATGATG CTATTAAGAA AGCCCACATA 
GAGAAGGATT TTATCGCTTT CTGCTCTTCC ACACCAGATA ATGTTTCTTG GAGACATCCC 
ACAATGGGCT CTGTTTTTAT TGGAAGACTC ATTGAACATA TGCAAGAATA TGCCTGTTCC 
TGTGATGTGG AGGAAATTTT CCGCAAGGTT CGATTTTCAT TTGAGCAGCC AGATGGTAGA 
GCGCAGATGC CCACCACTGA AAGAGTGACT TTGACAAGAT GTTTCTACCT CTTCCCAGGA 
CATTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016873883.1
CDS	402..1607
Translation	MYRPCQKGRRSILSVSVTQEGRREKPWPTRVLNKEEMEKVKRENATVMDKTRALIDSVIPKGAQACQICITYICEEDSYLAGTLGLSADQTSGNYLNMQDSQGVLSSFPAPQAVQDNPAMPTSSGSEGNVKLCSLEEAQRIWKQKSAEIYPIMDKSSRTRLALIICNEEFDSIPRRTGAEVDITGMTMLLQNLGYSVDVKKNLTASDMTTELEAFAHRPEHKTSDSTFLVFMSHGIREGICGKKHSEQVPDILQLNAIFNMLNTKNCPSLKDKPKVIIIQACRGDSPGVVWFKDSVGVSGNLSLPTTEEFEDDAIKKAHIEKDFIAFCSSTPDNVSWRHPTMGSVFIGRLIEHMQEYACSCDVEEIFRKVRFSFEQPDGRAQMPTTERVTLTRCFYLFPGH

Target ORF information:

RefSeq Version	XM_017018394.1
Organism	Homo sapiens(human)
Definition	Homo sapiens caspase 1 (CASP1), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017018394.1

ORF Insert Sequence:

ATGTACAGGC CCTGCCAAAA AGGAAGGCGA AGCATACTTT CAGTTTCAGT CACACAAGAA 
GGGAGGAGAG AAAAGCCATG GCCGACAAGG GTGCTGAACA AGGAAGAGAT GGAGAAAGTA 
AAACGTGAAA ATGCTACAGT TATGGATAAG ACCCGAGCTT TGATTGACTC CGTTATTCCG 
AAAGGGGCAC AGGCATGCCA AATTTGCATC ACATACATTT GTGAAGAAGA CAGTTACCTG 
GCAGGGACGC TGGGACTCTC AGCAGATCAA ACATCTGGAA ATTACCTTAA TATGCAAGAC 
TCTCAAGGAG TACTTTCTTC CTTTCCAGCT CCTCAGGCAG TGCAGGACAA CCCAGCTATG 
CCCACATCCT CAGGCTCAGA AGGGAATGTC AAGCTTTGCT CCCTAGAAGA AGCTCAAAGG 
ATATGGAAAC AAAAGTCGGC AGAGATTTAT CCAATAATGG ACAAGTCAAG CCGCACACGT 
CTTGCTCTCA TTATCTGCAA TGAAGAATTT GACAGTATTC CTAGAAGAAC TGGAGCTGAG 
GTTGACATCA CAGGCATGAC AATGCTGCTA CAAAATCTGG GGTACAGCGT AGATGTGAAA 
AAAAATCTCA CTGCTTCGGA CATGACTACA GAGCTGGAGG CATTTGCACA CCGCCCAGAG 
CACAAGACCT CTGACAGCAC GTTCCTGGTG TTCATGTCTC ATGGTATTCG GGAAGGCATT 
TGTGGGAAGA AACACTCTGA GCAAGTCCCA GATATACTAC AACTCAATGC AATCTTTAAC 
ATGTTGAATA CCAAGAACTG CCCAAGTTTG AAGGACAAAC CGAAGGTGAT CATCATCCAG 
GCCTGCCGTG GTGACAGCCC TGGTGTGGTG TGGTTTAAAG ATTCAGTAGG AGTTTCTGGA 
AACCTATCTT TACCAACTAC AGAAGAGTTT GAGGATGATG CTATTAAGAA AGCCCACATA 
GAGAAGGATT TTATCGCTTT CTGCTCTTCC ACACCAGATA ATGTTTCTTG GAGACATCCC 
ACAATGGGCT CTGTTTTTAT TGGAAGACTC ATTGAACATA TGCAAGAATA TGCCTGTTCC 
TGTGATGTGG AGGAAATTTT CCGCAAGGTT CGATTTTCAT TTGAGCAGCC AGATGGTAGA 
GCGCAGATGC CCACCACTGA AAGAGTGACT TTGACAAGAT GTTTCTACCT CTTCCCAGGA 
CATTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CASP1 ( XM_017018393.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016873882.1 Homo sapiens caspase 1 (CASP1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu92570
Clone ID Related Accession (Same CDS sequence)	XM_017018394.1 , XM_017018393.1
Accession Version	XM_017018393.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1206bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	caspase-1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000011.10) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTACAGGC CCTGCCAAAA AGGAAGGCGA AGCATACTTT CAGTTTCAGT CACACAAGAA 
GGGAGGAGAG AAAAGCCATG GCCGACAAGG GTGCTGAACA AGGAAGAGAT GGAGAAAGTA 
AAACGTGAAA ATGCTACAGT TATGGATAAG ACCCGAGCTT TGATTGACTC CGTTATTCCG 
AAAGGGGCAC AGGCATGCCA AATTTGCATC ACATACATTT GTGAAGAAGA CAGTTACCTG 
GCAGGGACGC TGGGACTCTC AGCAGATCAA ACATCTGGAA ATTACCTTAA TATGCAAGAC 
TCTCAAGGAG TACTTTCTTC CTTTCCAGCT CCTCAGGCAG TGCAGGACAA CCCAGCTATG 
CCCACATCCT CAGGCTCAGA AGGGAATGTC AAGCTTTGCT CCCTAGAAGA AGCTCAAAGG 
ATATGGAAAC AAAAGTCGGC AGAGATTTAT CCAATAATGG ACAAGTCAAG CCGCACACGT 
CTTGCTCTCA TTATCTGCAA TGAAGAATTT GACAGTATTC CTAGAAGAAC TGGAGCTGAG 
GTTGACATCA CAGGCATGAC AATGCTGCTA CAAAATCTGG GGTACAGCGT AGATGTGAAA 
AAAAATCTCA CTGCTTCGGA CATGACTACA GAGCTGGAGG CATTTGCACA CCGCCCAGAG 
CACAAGACCT CTGACAGCAC GTTCCTGGTG TTCATGTCTC ATGGTATTCG GGAAGGCATT 
TGTGGGAAGA AACACTCTGA GCAAGTCCCA GATATACTAC AACTCAATGC AATCTTTAAC 
ATGTTGAATA CCAAGAACTG CCCAAGTTTG AAGGACAAAC CGAAGGTGAT CATCATCCAG 
GCCTGCCGTG GTGACAGCCC TGGTGTGGTG TGGTTTAAAG ATTCAGTAGG AGTTTCTGGA 
AACCTATCTT TACCAACTAC AGAAGAGTTT GAGGATGATG CTATTAAGAA AGCCCACATA 
GAGAAGGATT TTATCGCTTT CTGCTCTTCC ACACCAGATA ATGTTTCTTG GAGACATCCC 
ACAATGGGCT CTGTTTTTAT TGGAAGACTC ATTGAACATA TGCAAGAATA TGCCTGTTCC 
TGTGATGTGG AGGAAATTTT CCGCAAGGTT CGATTTTCAT TTGAGCAGCC AGATGGTAGA 
GCGCAGATGC CCACCACTGA AAGAGTGACT TTGACAAGAT GTTTCTACCT CTTCCCAGGA 
CATTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016873882.1
CDS	402..1607
Translation	MYRPCQKGRRSILSVSVTQEGRREKPWPTRVLNKEEMEKVKRENATVMDKTRALIDSVIPKGAQACQICITYICEEDSYLAGTLGLSADQTSGNYLNMQDSQGVLSSFPAPQAVQDNPAMPTSSGSEGNVKLCSLEEAQRIWKQKSAEIYPIMDKSSRTRLALIICNEEFDSIPRRTGAEVDITGMTMLLQNLGYSVDVKKNLTASDMTTELEAFAHRPEHKTSDSTFLVFMSHGIREGICGKKHSEQVPDILQLNAIFNMLNTKNCPSLKDKPKVIIIQACRGDSPGVVWFKDSVGVSGNLSLPTTEEFEDDAIKKAHIEKDFIAFCSSTPDNVSWRHPTMGSVFIGRLIEHMQEYACSCDVEEIFRKVRFSFEQPDGRAQMPTTERVTLTRCFYLFPGH

Target ORF information:

RefSeq Version	XM_017018393.1
Organism	Homo sapiens(human)
Definition	Homo sapiens caspase 1 (CASP1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017018393.1

ORF Insert Sequence:

ATGTACAGGC CCTGCCAAAA AGGAAGGCGA AGCATACTTT CAGTTTCAGT CACACAAGAA 
GGGAGGAGAG AAAAGCCATG GCCGACAAGG GTGCTGAACA AGGAAGAGAT GGAGAAAGTA 
AAACGTGAAA ATGCTACAGT TATGGATAAG ACCCGAGCTT TGATTGACTC CGTTATTCCG 
AAAGGGGCAC AGGCATGCCA AATTTGCATC ACATACATTT GTGAAGAAGA CAGTTACCTG 
GCAGGGACGC TGGGACTCTC AGCAGATCAA ACATCTGGAA ATTACCTTAA TATGCAAGAC 
TCTCAAGGAG TACTTTCTTC CTTTCCAGCT CCTCAGGCAG TGCAGGACAA CCCAGCTATG 
CCCACATCCT CAGGCTCAGA AGGGAATGTC AAGCTTTGCT CCCTAGAAGA AGCTCAAAGG 
ATATGGAAAC AAAAGTCGGC AGAGATTTAT CCAATAATGG ACAAGTCAAG CCGCACACGT 
CTTGCTCTCA TTATCTGCAA TGAAGAATTT GACAGTATTC CTAGAAGAAC TGGAGCTGAG 
GTTGACATCA CAGGCATGAC AATGCTGCTA CAAAATCTGG GGTACAGCGT AGATGTGAAA 
AAAAATCTCA CTGCTTCGGA CATGACTACA GAGCTGGAGG CATTTGCACA CCGCCCAGAG 
CACAAGACCT CTGACAGCAC GTTCCTGGTG TTCATGTCTC ATGGTATTCG GGAAGGCATT 
TGTGGGAAGA AACACTCTGA GCAAGTCCCA GATATACTAC AACTCAATGC AATCTTTAAC 
ATGTTGAATA CCAAGAACTG CCCAAGTTTG AAGGACAAAC CGAAGGTGAT CATCATCCAG 
GCCTGCCGTG GTGACAGCCC TGGTGTGGTG TGGTTTAAAG ATTCAGTAGG AGTTTCTGGA 
AACCTATCTT TACCAACTAC AGAAGAGTTT GAGGATGATG CTATTAAGAA AGCCCACATA 
GAGAAGGATT TTATCGCTTT CTGCTCTTCC ACACCAGATA ATGTTTCTTG GAGACATCCC 
ACAATGGGCT CTGTTTTTAT TGGAAGACTC ATTGAACATA TGCAAGAATA TGCCTGTTCC 
TGTGATGTGG AGGAAATTTT CCGCAAGGTT CGATTTTCAT TTGAGCAGCC AGATGGTAGA 
GCGCAGATGC CCACCACTGA AAGAGTGACT TTGACAAGAT GTTTCTACCT CTTCCCAGGA 
CATTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CASP1 ( XM_017018395.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016873884.1 Homo sapiens caspase 1 (CASP1), transcript variant X3, mRNA.

Price & Availability↑

CloneID	OHu92571
Clone ID Related Accession (Same CDS sequence)	XM_017018395.1
Accession Version	XM_017018395.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1143bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	caspase-1 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000011.10) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTACAGGC CCTGCCAAAA AGGAAGGCGA AGCATACTTT CAGTTTCAGT CACACAAGAA 
GGGAGGAGAG AAAAGCCATG GCCGACAAGG GTGCTGAACA AGGAAGAGAT GGAGAAAGTA 
AAACGTGAAA ATGCTACAGT TATGGATAAG ACCCGAGCTT TGATTGACTC CGTTATTCCG 
AAAGGGGCAC AGGCATGCCA AATTTGCATC ACATACATTT GTGAAGAAGA CAGTTACCTG 
GCAGGGACGC TGGGACTCTC AGCAGCTCCT CAGGCAGTGC AGGACAACCC AGCTATGCCC 
ACATCCTCAG GCTCAGAAGG GAATGTCAAG CTTTGCTCCC TAGAAGAAGC TCAAAGGATA 
TGGAAACAAA AGTCGGCAGA GATTTATCCA ATAATGGACA AGTCAAGCCG CACACGTCTT 
GCTCTCATTA TCTGCAATGA AGAATTTGAC AGTATTCCTA GAAGAACTGG AGCTGAGGTT 
GACATCACAG GCATGACAAT GCTGCTACAA AATCTGGGGT ACAGCGTAGA TGTGAAAAAA 
AATCTCACTG CTTCGGACAT GACTACAGAG CTGGAGGCAT TTGCACACCG CCCAGAGCAC 
AAGACCTCTG ACAGCACGTT CCTGGTGTTC ATGTCTCATG GTATTCGGGA AGGCATTTGT 
GGGAAGAAAC ACTCTGAGCA AGTCCCAGAT ATACTACAAC TCAATGCAAT CTTTAACATG 
TTGAATACCA AGAACTGCCC AAGTTTGAAG GACAAACCGA AGGTGATCAT CATCCAGGCC 
TGCCGTGGTG ACAGCCCTGG TGTGGTGTGG TTTAAAGATT CAGTAGGAGT TTCTGGAAAC 
CTATCTTTAC CAACTACAGA AGAGTTTGAG GATGATGCTA TTAAGAAAGC CCACATAGAG 
AAGGATTTTA TCGCTTTCTG CTCTTCCACA CCAGATAATG TTTCTTGGAG ACATCCCACA 
ATGGGCTCTG TTTTTATTGG AAGACTCATT GAACATATGC AAGAATATGC CTGTTCCTGT 
GATGTGGAGG AAATTTTCCG CAAGGTTCGA TTTTCATTTG AGCAGCCAGA TGGTAGAGCG 
CAGATGCCCA CCACTGAAAG AGTGACTTTG ACAAGATGTT TCTACCTCTT CCCAGGACAT 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016873884.1
CDS	402..1544
Translation	MYRPCQKGRRSILSVSVTQEGRREKPWPTRVLNKEEMEKVKRENATVMDKTRALIDSVIPKGAQACQICITYICEEDSYLAGTLGLSAAPQAVQDNPAMPTSSGSEGNVKLCSLEEAQRIWKQKSAEIYPIMDKSSRTRLALIICNEEFDSIPRRTGAEVDITGMTMLLQNLGYSVDVKKNLTASDMTTELEAFAHRPEHKTSDSTFLVFMSHGIREGICGKKHSEQVPDILQLNAIFNMLNTKNCPSLKDKPKVIIIQACRGDSPGVVWFKDSVGVSGNLSLPTTEEFEDDAIKKAHIEKDFIAFCSSTPDNVSWRHPTMGSVFIGRLIEHMQEYACSCDVEEIFRKVRFSFEQPDGRAQMPTTERVTLTRCFYLFPGH

Target ORF information:

RefSeq Version	XM_017018395.1
Organism	Homo sapiens(human)
Definition	Homo sapiens caspase 1 (CASP1), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017018395.1

ORF Insert Sequence:

ATGTACAGGC CCTGCCAAAA AGGAAGGCGA AGCATACTTT CAGTTTCAGT CACACAAGAA 
GGGAGGAGAG AAAAGCCATG GCCGACAAGG GTGCTGAACA AGGAAGAGAT GGAGAAAGTA 
AAACGTGAAA ATGCTACAGT TATGGATAAG ACCCGAGCTT TGATTGACTC CGTTATTCCG 
AAAGGGGCAC AGGCATGCCA AATTTGCATC ACATACATTT GTGAAGAAGA CAGTTACCTG 
GCAGGGACGC TGGGACTCTC AGCAGCTCCT CAGGCAGTGC AGGACAACCC AGCTATGCCC 
ACATCCTCAG GCTCAGAAGG GAATGTCAAG CTTTGCTCCC TAGAAGAAGC TCAAAGGATA 
TGGAAACAAA AGTCGGCAGA GATTTATCCA ATAATGGACA AGTCAAGCCG CACACGTCTT 
GCTCTCATTA TCTGCAATGA AGAATTTGAC AGTATTCCTA GAAGAACTGG AGCTGAGGTT 
GACATCACAG GCATGACAAT GCTGCTACAA AATCTGGGGT ACAGCGTAGA TGTGAAAAAA 
AATCTCACTG CTTCGGACAT GACTACAGAG CTGGAGGCAT TTGCACACCG CCCAGAGCAC 
AAGACCTCTG ACAGCACGTT CCTGGTGTTC ATGTCTCATG GTATTCGGGA AGGCATTTGT 
GGGAAGAAAC ACTCTGAGCA AGTCCCAGAT ATACTACAAC TCAATGCAAT CTTTAACATG 
TTGAATACCA AGAACTGCCC AAGTTTGAAG GACAAACCGA AGGTGATCAT CATCCAGGCC 
TGCCGTGGTG ACAGCCCTGG TGTGGTGTGG TTTAAAGATT CAGTAGGAGT TTCTGGAAAC 
CTATCTTTAC CAACTACAGA AGAGTTTGAG GATGATGCTA TTAAGAAAGC CCACATAGAG 
AAGGATTTTA TCGCTTTCTG CTCTTCCACA CCAGATAATG TTTCTTGGAG ACATCCCACA 
ATGGGCTCTG TTTTTATTGG AAGACTCATT GAACATATGC AAGAATATGC CTGTTCCTGT 
GATGTGGAGG AAATTTTCCG CAAGGTTCGA TTTTCATTTG AGCAGCCAGA TGGTAGAGCG 
CAGATGCCCA CCACTGAAAG AGTGACTTTG ACAAGATGTT TCTACCTCTT CCCAGGACAT 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Gene Symbol	CASP1
Entrez Gene ID	834
Full Name	caspase 1
Synonyms	ICE,IL1BC,P45
General protein information	Preferred Names caspase 1 Names caspase-1 CASP1 nirs variant 1 IL-1 beta-converting enzyme IL1B-convertase caspase 1, apoptosis-related cysteine peptidase interleukin 1, beta, convertase interleukin 1-B converting enzyme
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 11 Map Location: 11q22.3
Summary	This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce 2 subunits, large and small, that dimerize to form the active enzyme. This gene was identified by its ability to proteolytically cleave and activate the inactive precursor of interleukin-1, a cytokine involved in the processes such as inflammation, septic shock, and wound healing. This gene has been shown to induce cell apoptosis and may function in various developmental stages. Studies of a similar gene in mouse suggest a role in the pathogenesis of Huntington disease. Alternative splicing results in transcript variants encoding distinct isoforms. [provided by RefSeq, Mar 2012].
Disorder MIM:	147678

Canis lupus familiaris (dog)	CASP4	NP_001003125.1
Mus musculus (house mouse)	Casp1	NP_033937.2
Gallus gallus (chicken)	CASP1	XP_003642432.2
Danio rerio (zebrafish)	caspbl	NP_001139064.1
Homo sapiens (human)	CASP1	NP_150634.1
Pan troglodytes (chimpanzee)	LOC101058924	XP_003952059.1
Danio rerio (zebrafish)	caspa	NP_571580.1
Danio rerio (zebrafish)	si:ch211-233g6.8	XP_003197824.1
	CASP1	XP_001094943.2
Bos taurus (cattle)	CASP1	XP_002692967.1
Rattus norvegicus (Norway rat)	Casp1	NP_036894.2
Danio rerio (zebrafish)	zgc:171731	NP_001103182.1
Xenopus tropicalis (tropical clawed frog)	LOC100491605	XP_002935240.2

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

CASP1 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

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