FZD9 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	FZD9
Entrez Gene ID	8326
Full Name	frizzled class receptor 9
Synonyms	CD349,FZD3
General protein information	Preferred Names frizzled class receptor 9 Names frizzled-9 frizzled 9, seven transmembrane spanning receptor frizzled family receptor 9 frizzled homolog 9 fz-9 fzE6 hFz9
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 7 Map Location: 7q11.23
Summary	Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD9 gene is located within the Williams syndrome common deletion region of chromosome 7, and heterozygous deletion of the FZD9 gene may contribute to the Williams syndrome phenotype. FZD9 is expressed predominantly in brain, testis, eye, skeletal muscle, and kidney. [provided by RefSeq, Jul 2008].
Disorder MIM:	601766

mRNA and Protein(s)

mRNA	Protein	Name
NM_003508.2	NP_003499.1	frizzled-9 precursor
NM_003508.3	NP_003499.1	frizzled-9 precursor

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	FZD9	XP_527779.3
Gallus gallus (chicken)	FZD9	NP_001263212.1
Homo sapiens (human)	FZD9	NP_003499.1
Bos taurus (cattle)	FZD9	XP_002698235.1
Danio rerio (zebrafish)	fzd9b	NP_571586.1
Xenopus tropicalis (tropical clawed frog)	fzd9	XP_004911821.1
Canis lupus familiaris (dog)	FZD9	XP_546927.2
Rattus norvegicus (Norway rat)	Fzd9	NP_695217.1
Mus musculus (house mouse)	Fzd9	NP_034376.1
Danio rerio (zebrafish)	fzd9	XP_003198734.1

Gene Ontology
Bibliography

Related articles in PubMed

Involvement of c-Fos in cell proliferation, migration, and invasion in osteosarcoma cells accompanied by altered expression of Wnt2 and Fzd9.
Wang Q, Liu H, Wang Q, Zhou F, Liu Y, Zhang Y, Ding H, Yuan M, Li F, Chen Y
PloS one12(6)e0180558(2017)

Methylation status of the promoter region of the human frizzled 9 gene in acute myeloid leukemia.
Zhang Y, Jiang Q, Kong X, Yang L, Hu W, Lv C, Li Y
Molecular medicine reports14(2)1339-44(2016 Aug)

A human neurodevelopmental model for Williams syndrome.
Chailangkarn T, Trujillo CA, Freitas BC, Hrvoj-Mihic B, Herai RH, Yu DX, Brown TT, Marchetto MC, Bardy C, McHenry L, Stefanacci L, J?rvinen A, Searcy YM, DeWitt M, Wong W, Lai P, Ard MC, Hanson KL, Romero S, Jacobs B, Dale AM, Dai L, Korenberg JR, Gage FH, Bellugi U, Halgren E, Semendeferi K, Muotri AR
Nature536(7616)338-43(2016 08)

Expression profile of the embryonic markers nanog, OCT-4, SSEA-1, SSEA-4, and frizzled-9 receptor in human periodontal ligament mesenchymal stem cells.
Trubiani O, Zalzal SF, Paganelli R, Marchisio M, Giancola R, Pizzicannella J, B?hring HJ, Piattelli M, Caputi S, Nanci A
Journal of cellular physiology225(1)123-31(2010 Oct)

Sprouty-4 inhibits transformed cell growth, migration and invasion, and epithelial-mesenchymal transition, and is regulated by Wnt7A through PPARgamma in non-small cell lung cancer.
Tennis MA, Van Scoyk MM, Freeman SV, Vandervest KM, Nemenoff RA, Winn RA
Molecular cancer research : MCR8(6)833-43(2010 Jun)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

data enforced the evidence that knockdown of c-Fos inhibited cell proliferation, migration, and invasion, and promoted the apoptosis of OS cells accompanied by altered expression of Wnt2 and Fzd9
Title: Involvement of c-Fos in cell proliferation, migration, and invasion in osteosarcoma cells accompanied by altered expression of Wnt2 and Fzd9.

the present study indicated that the methylation profile of the FZD9 gene corresponded to that of a candidate tumorsuppressor gene in acute myeloid leukemia.
Title: Methylation status of the promoter region of the human frizzled 9 gene in acute myeloid leukemia.

The presence of nanog, Oct-4, SSEA-1, and SSEA-4 suggests that periodontal ligament mesenchymal stem cells are less differentiated than bone marrow-derived MSCs, and that the frizzled-9/Wnt pathway is important in proliferation and differentiation.
Title: Expression profile of the embryonic markers nanog, OCT-4, SSEA-1, SSEA-4, and frizzled-9 receptor in human periodontal ligament mesenchymal stem cells.

Observational study of gene-disease association. (HuGE Navigator)
Title: Comprehensive copy number variant (CNV) analysis of neuronal pathways genes in psychiatric disorders identifies rare variants within patients.

The activity of the Sprouty4 promoter is increased by Wnt7A/Fzd9 signaling through peroxisome proliferator-activated receptor gamma in lung cancer cells.
Title: Sprouty-4 inhibits transformed cell growth, migration and invasion, and epithelial-mesenchymal transition, and is regulated by Wnt7A through PPARgamma in non-small cell lung cancer.

The following FZD9 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the FZD9 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu18257	NM_003508.3 Latest version!	Homo sapiens frizzled class receptor 9 (FZD9), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$219.50-$307.30 $439.00
View Old Accession Versions >>
OHu18257	NM_003508.2	Homo sapiens frizzled class receptor 9 (FZD9), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$219.50-$307.30 $439.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

FZD9 ( NM_003508.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_003499.1 Homo sapiens frizzled class receptor 9 (FZD9), mRNA.

Price & Availability↑

CloneID	OHu18257
Clone ID Related Accession (Same CDS sequence)	NM_003508.2 , NM_003508.3
Accession Version	NM_003508.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1776bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-16
Organism	Homo sapiens(human)
Product	frizzled-9 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC005049.2 and U82169.1. This sequence is a reference standard in the RefSeqGene project. On Apr 22, 2005 this sequence version replaced NM_003508.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript is intronless :: BC026333.1 [ECO:0000345] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCCGTGG CGCCTCTGCG GGGGGCGCTG CTGCTGTGGC AGCTGCTGGC GGCGGGCGGC 
GCGGCACTGG AGATCGGCCG CTTCGACCCG GAGCGCGGGC GCGGGGCTGC GCCGTGCCAG 
GCGGTGGAGA TCCCCATGTG CCGCGGCATC GGCTACAACC TGACCCGCAT GCCCAACCTG 
CTGGGCCACA CGTCGCAGGG CGAGGCGGCT GCCGAGCTAG CGGAGTTCGC GCCGCTGGTG 
CAGTACGGCT GCCACAGCCA CCTGCGCTTC TTCCTGTGCT CGCTCTACGC GCCCATGTGC 
ACCGACCAGG TCTCGACGCC CATTCCCGCC TGCCGGCCCA TGTGCGAGCA GGCGCGCCTG 
CGCTGCGCGC CCATCATGGA GCAGTTCAAC TTCGGCTGGC CGGACTCGCT CGACTGCGCC 
CGGCTGCCCA CGCGCAACGA CCCGCACGCG CTGTGCATGG AGGCGCCCGA GAACGCCACG 
GCCGGCCCCG CGGAGCCCCA CAAGGGCCTG GGCATGCTGC CCGTGGCGCC GCGGCCCGCG 
CGCCCTCCCG GAGACCTGGG CCCGGGCGCG GGCGGCAGTG GCACCTGCGA GAACCCCGAG 
AAGTTCCAGT ACGTGGAGAA GAGCCGCTCG TGCGCACCGC GCTGCGGGCC CGGCGTCGAG 
GTGTTCTGGT CCCGGCGCGA CAAGGACTTC GCGCTGGTCT GGATGGCCGT GTGGTCGGCG 
CTGTGCTTCT TCTCCACCGC CTTCACTGTG CTCACCTTCT TGCTGGAGCC CCACCGCTTC 
CAGTACCCCG AGCGCCCCAT CATCTTCCTC TCCATGTGCT ACAACGTCTA CTCGCTGGCC 
TTCCTGATCC GTGCGGTGGC CGGAGCGCAG AGCGTGGCCT GTGACCAGGA GGCGGGCGCG 
CTCTACGTGA TCCAGGAGGG CCTGGAGAAC ACGGGCTGCA CGCTGGTCTT CCTACTGCTC 
TACTACTTCG GCATGGCCAG CTCGCTCTGG TGGGTGGTCC TGACGCTCAC CTGGTTCCTG 
GCTGCCGGGA AGAAATGGGG CCACGAGGCC ATCGAGGCCC ACGGCAGCTA TTTCCACATG 
GCTGCCTGGG GCCTGCCCGC GCTCAAGACC ATCGTCATCC TGACCCTGCG CAAGGTGGCG 
GGTGATGAGC TGACTGGGCT TTGCTACGTG GCCAGCACGG ATGCAGCAGC GCTCACGGGC 
TTCGTGCTGG TGCCCCTCTC TGGCTACCTG GTGCTGGGCA GTAGTTTCCT CCTGACCGGC 
TTCGTGGCCC TCTTCCACAT CCGCAAGATC ATGAAGACGG GCGGCACCAA CACAGAGAAG 
CTGGAGAAGC TCATGGTCAA GATCGGGGTC TTCTCCATCC TCTACACGGT GCCCGCCACC 
TGCGTCATCG TTTGCTATGT CTACGAACGC CTCAACATGG ACTTCTGGCG CCTTCGGGCC 
ACAGAGCAGC CATGCGCAGC GGCCGCGGGG CCCGGAGGCC GGAGGGACTG CTCGCTGCCA 
GGGGGCTCGG TGCCCACCGT GGCGGTCTTC ATGCTCAAAA TTTTCATGTC ACTGGTGGTG 
GGGATCACCA GCGGCGTCTG GGTGTGGAGC TCCAAGACTT TCCAGACCTG GCAGAGCCTG 
TGCTACCGCA AGATAGCAGC TGGCCGGGCC CGGGCCAAGG CCTGCCGCGC CCCCGGGAGC 
TACGGACGTG GCACGCACTG CCACTATAAG GCTCCCACCG TGGTCTTGCA CATGACTAAG 
ACGGACCCCT CTTTGGAGAA CCCCACACAC CTCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_003499.1
CDS	230..2005
Translation	MAVAPLRGALLLWQLLAAGGAALEIGRFDPERGRGAAPCQAVEIPMCRGIGYNLTRMPNLLGHTSQGEAAAELAEFAPLVQYGCHSHLRFFLCSLYAPMCTDQVSTPIPACRPMCEQARLRCAPIMEQFNFGWPDSLDCARLPTRNDPHALCMEAPENATAGPAEPHKGLGMLPVAPRPARPPGDLGPGAGGSGTCENPEKFQYVEKSRSCAPRCGPGVEVFWSRRDKDFALVWMAVWSALCFFSTAFTVLTFLLEPHRFQYPERPIIFLSMCYNVYSLAFLIRAVAGAQSVACDQEAGALYVIQEGLENTGCTLVFLLLYYFGMASSLWWVVLTLTWFLAAGKKWGHEAIEAHGSYFHMAAWGLPALKTIVILTLRKVAGDELTGLCYVASTDAAALTGFVLVPLSGYLVLGSSFLLTGFVALFHIRKIMKTGGTNTEKLEKLMVKIGVFSILYTVPATCVIVCYVYERLNMDFWRLRATEQPCAAAAGPGGRRDCSLPGGSVPTVAVFMLKIFMSLVVGITSGVWVWSSKTFQTWQSLCYRKIAAGRARAKACRAPGSYGRGTHCHYKAPTVVLHMTKTDPSLENPTHL

Target ORF information:

RefSeq Version	NM_003508.2
Organism	Homo sapiens(human)
Definition	Homo sapiens frizzled class receptor 9 (FZD9), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_003508.2

ORF Insert Sequence:

ATGGCCGTGG CGCCTCTGCG GGGGGCGCTG CTGCTGTGGC AGCTGCTGGC GGCGGGCGGC 
GCGGCACTGG AGATCGGCCG CTTCGACCCG GAGCGCGGGC GCGGGGCTGC GCCGTGCCAG 
GCGGTGGAGA TCCCCATGTG CCGCGGCATC GGCTACAACC TGACCCGCAT GCCCAACCTG 
CTGGGCCACA CGTCGCAGGG CGAGGCGGCT GCCGAGCTAG CGGAGTTCGC GCCGCTGGTG 
CAGTACGGCT GCCACAGCCA CCTGCGCTTC TTCCTGTGCT CGCTCTACGC GCCCATGTGC 
ACCGACCAGG TCTCGACGCC CATTCCCGCC TGCCGGCCCA TGTGCGAGCA GGCGCGCCTG 
CGCTGCGCGC CCATCATGGA GCAGTTCAAC TTCGGCTGGC CGGACTCGCT CGACTGCGCC 
CGGCTGCCCA CGCGCAACGA CCCGCACGCG CTGTGCATGG AGGCGCCCGA GAACGCCACG 
GCCGGCCCCG CGGAGCCCCA CAAGGGCCTG GGCATGCTGC CCGTGGCGCC GCGGCCCGCG 
CGCCCTCCCG GAGACCTGGG CCCGGGCGCG GGCGGCAGTG GCACCTGCGA GAACCCCGAG 
AAGTTCCAGT ACGTGGAGAA GAGCCGCTCG TGCGCACCGC GCTGCGGGCC CGGCGTCGAG 
GTGTTCTGGT CCCGGCGCGA CAAGGACTTC GCGCTGGTCT GGATGGCCGT GTGGTCGGCG 
CTGTGCTTCT TCTCCACCGC CTTCACTGTG CTCACCTTCT TGCTGGAGCC CCACCGCTTC 
CAGTACCCCG AGCGCCCCAT CATCTTCCTC TCCATGTGCT ACAACGTCTA CTCGCTGGCC 
TTCCTGATCC GTGCGGTGGC CGGAGCGCAG AGCGTGGCCT GTGACCAGGA GGCGGGCGCG 
CTCTACGTGA TCCAGGAGGG CCTGGAGAAC ACGGGCTGCA CGCTGGTCTT CCTACTGCTC 
TACTACTTCG GCATGGCCAG CTCGCTCTGG TGGGTGGTCC TGACGCTCAC CTGGTTCCTG 
GCTGCCGGGA AGAAATGGGG CCACGAGGCC ATCGAGGCCC ACGGCAGCTA TTTCCACATG 
GCTGCCTGGG GCCTGCCCGC GCTCAAGACC ATCGTCATCC TGACCCTGCG CAAGGTGGCG 
GGTGATGAGC TGACTGGGCT TTGCTACGTG GCCAGCACGG ATGCAGCAGC GCTCACGGGC 
TTCGTGCTGG TGCCCCTCTC TGGCTACCTG GTGCTGGGCA GTAGTTTCCT CCTGACCGGC 
TTCGTGGCCC TCTTCCACAT CCGCAAGATC ATGAAGACGG GCGGCACCAA CACAGAGAAG 
CTGGAGAAGC TCATGGTCAA GATCGGGGTC TTCTCCATCC TCTACACGGT GCCCGCCACC 
TGCGTCATCG TTTGCTATGT CTACGAACGC CTCAACATGG ACTTCTGGCG CCTTCGGGCC 
ACAGAGCAGC CATGCGCAGC GGCCGCGGGG CCCGGAGGCC GGAGGGACTG CTCGCTGCCA 
GGGGGCTCGG TGCCCACCGT GGCGGTCTTC ATGCTCAAAA TTTTCATGTC ACTGGTGGTG 
GGGATCACCA GCGGCGTCTG GGTGTGGAGC TCCAAGACTT TCCAGACCTG GCAGAGCCTG 
TGCTACCGCA AGATAGCAGC TGGCCGGGCC CGGGCCAAGG CCTGCCGCGC CCCCGGGAGC 
TACGGACGTG GCACGCACTG CCACTATAAG GCTCCCACCG TGGTCTTGCA CATGACTAAG 
ACGGACCCCT CTTTGGAGAA CCCCACACAC CTCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

FZD9 ( NM_003508.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_003499.1 Homo sapiens frizzled class receptor 9 (FZD9), mRNA.

Price & Availability↑

CloneID	OHu18257
Clone ID Related Accession (Same CDS sequence)	NM_003508.2 , NM_003508.3
Accession Version	NM_003508.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1776bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2020-01-01
Organism	Homo sapiens(human)
Product	frizzled-9 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC005049.2 and U82169.1. This sequence is a reference standard in the RefSeqGene project. On May 17, 2019 this sequence version replaced NM_003508.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript is intronless :: BC026333.1, U82169.1 [ECO:0000345] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000344575.5/ ENSP00000345785.3 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGCCGTGG CGCCTCTGCG GGGGGCGCTG CTGCTGTGGC AGCTGCTGGC GGCGGGCGGC 
GCGGCACTGG AGATCGGCCG CTTCGACCCG GAGCGCGGGC GCGGGGCTGC GCCGTGCCAG 
GCGGTGGAGA TCCCCATGTG CCGCGGCATC GGCTACAACC TGACCCGCAT GCCCAACCTG 
CTGGGCCACA CGTCGCAGGG CGAGGCGGCT GCCGAGCTAG CGGAGTTCGC GCCGCTGGTG 
CAGTACGGCT GCCACAGCCA CCTGCGCTTC TTCCTGTGCT CGCTCTACGC GCCCATGTGC 
ACCGACCAGG TCTCGACGCC CATTCCCGCC TGCCGGCCCA TGTGCGAGCA GGCGCGCCTG 
CGCTGCGCGC CCATCATGGA GCAGTTCAAC TTCGGCTGGC CGGACTCGCT CGACTGCGCC 
CGGCTGCCCA CGCGCAACGA CCCGCACGCG CTGTGCATGG AGGCGCCCGA GAACGCCACG 
GCCGGCCCCG CGGAGCCCCA CAAGGGCCTG GGCATGCTGC CCGTGGCGCC GCGGCCCGCG 
CGCCCTCCCG GAGACCTGGG CCCGGGCGCG GGCGGCAGTG GCACCTGCGA GAACCCCGAG 
AAGTTCCAGT ACGTGGAGAA GAGCCGCTCG TGCGCACCGC GCTGCGGGCC CGGCGTCGAG 
GTGTTCTGGT CCCGGCGCGA CAAGGACTTC GCGCTGGTCT GGATGGCCGT GTGGTCGGCG 
CTGTGCTTCT TCTCCACCGC CTTCACTGTG CTCACCTTCT TGCTGGAGCC CCACCGCTTC 
CAGTACCCCG AGCGCCCCAT CATCTTCCTC TCCATGTGCT ACAACGTCTA CTCGCTGGCC 
TTCCTGATCC GTGCGGTGGC CGGAGCGCAG AGCGTGGCCT GTGACCAGGA GGCGGGCGCG 
CTCTACGTGA TCCAGGAGGG CCTGGAGAAC ACGGGCTGCA CGCTGGTCTT CCTACTGCTC 
TACTACTTCG GCATGGCCAG CTCGCTCTGG TGGGTGGTCC TGACGCTCAC CTGGTTCCTG 
GCTGCCGGGA AGAAATGGGG CCACGAGGCC ATCGAGGCCC ACGGCAGCTA TTTCCACATG 
GCTGCCTGGG GCCTGCCCGC GCTCAAGACC ATCGTCATCC TGACCCTGCG CAAGGTGGCG 
GGTGATGAGC TGACTGGGCT TTGCTACGTG GCCAGCACGG ATGCAGCAGC GCTCACGGGC 
TTCGTGCTGG TGCCCCTCTC TGGCTACCTG GTGCTGGGCA GTAGTTTCCT CCTGACCGGC 
TTCGTGGCCC TCTTCCACAT CCGCAAGATC ATGAAGACGG GCGGCACCAA CACAGAGAAG 
CTGGAGAAGC TCATGGTCAA GATCGGGGTC TTCTCCATCC TCTACACGGT GCCCGCCACC 
TGCGTCATCG TTTGCTATGT CTACGAACGC CTCAACATGG ACTTCTGGCG CCTTCGGGCC 
ACAGAGCAGC CATGCGCAGC GGCCGCGGGG CCCGGAGGCC GGAGGGACTG CTCGCTGCCA 
GGGGGCTCGG TGCCCACCGT GGCGGTCTTC ATGCTCAAAA TTTTCATGTC ACTGGTGGTG 
GGGATCACCA GCGGCGTCTG GGTGTGGAGC TCCAAGACTT TCCAGACCTG GCAGAGCCTG 
TGCTACCGCA AGATAGCAGC TGGCCGGGCC CGGGCCAAGG CCTGCCGCGC CCCCGGGAGC 
TACGGACGTG GCACGCACTG CCACTATAAG GCTCCCACCG TGGTCTTGCA CATGACTAAG 
ACGGACCCCT CTTTGGAGAA CCCCACACAC CTCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_003499.1
CDS	231..2006
Translation	MAVAPLRGALLLWQLLAAGGAALEIGRFDPERGRGAAPCQAVEIPMCRGIGYNLTRMPNLLGHTSQGEAAAELAEFAPLVQYGCHSHLRFFLCSLYAPMCTDQVSTPIPACRPMCEQARLRCAPIMEQFNFGWPDSLDCARLPTRNDPHALCMEAPENATAGPAEPHKGLGMLPVAPRPARPPGDLGPGAGGSGTCENPEKFQYVEKSRSCAPRCGPGVEVFWSRRDKDFALVWMAVWSALCFFSTAFTVLTFLLEPHRFQYPERPIIFLSMCYNVYSLAFLIRAVAGAQSVACDQEAGALYVIQEGLENTGCTLVFLLLYYFGMASSLWWVVLTLTWFLAAGKKWGHEAIEAHGSYFHMAAWGLPALKTIVILTLRKVAGDELTGLCYVASTDAAALTGFVLVPLSGYLVLGSSFLLTGFVALFHIRKIMKTGGTNTEKLEKLMVKIGVFSILYTVPATCVIVCYVYERLNMDFWRLRATEQPCAAAAGPGGRRDCSLPGGSVPTVAVFMLKIFMSLVVGITSGVWVWSSKTFQTWQSLCYRKIAAGRARAKACRAPGSYGRGTHCHYKAPTVVLHMTKTDPSLENPTHL

Target ORF information:

RefSeq Version	NM_003508.3
Organism	Homo sapiens(human)
Definition	Homo sapiens frizzled class receptor 9 (FZD9), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_003508.3

ORF Insert Sequence:

ATGGCCGTGG CGCCTCTGCG GGGGGCGCTG CTGCTGTGGC AGCTGCTGGC GGCGGGCGGC 
GCGGCACTGG AGATCGGCCG CTTCGACCCG GAGCGCGGGC GCGGGGCTGC GCCGTGCCAG 
GCGGTGGAGA TCCCCATGTG CCGCGGCATC GGCTACAACC TGACCCGCAT GCCCAACCTG 
CTGGGCCACA CGTCGCAGGG CGAGGCGGCT GCCGAGCTAG CGGAGTTCGC GCCGCTGGTG 
CAGTACGGCT GCCACAGCCA CCTGCGCTTC TTCCTGTGCT CGCTCTACGC GCCCATGTGC 
ACCGACCAGG TCTCGACGCC CATTCCCGCC TGCCGGCCCA TGTGCGAGCA GGCGCGCCTG 
CGCTGCGCGC CCATCATGGA GCAGTTCAAC TTCGGCTGGC CGGACTCGCT CGACTGCGCC 
CGGCTGCCCA CGCGCAACGA CCCGCACGCG CTGTGCATGG AGGCGCCCGA GAACGCCACG 
GCCGGCCCCG CGGAGCCCCA CAAGGGCCTG GGCATGCTGC CCGTGGCGCC GCGGCCCGCG 
CGCCCTCCCG GAGACCTGGG CCCGGGCGCG GGCGGCAGTG GCACCTGCGA GAACCCCGAG 
AAGTTCCAGT ACGTGGAGAA GAGCCGCTCG TGCGCACCGC GCTGCGGGCC CGGCGTCGAG 
GTGTTCTGGT CCCGGCGCGA CAAGGACTTC GCGCTGGTCT GGATGGCCGT GTGGTCGGCG 
CTGTGCTTCT TCTCCACCGC CTTCACTGTG CTCACCTTCT TGCTGGAGCC CCACCGCTTC 
CAGTACCCCG AGCGCCCCAT CATCTTCCTC TCCATGTGCT ACAACGTCTA CTCGCTGGCC 
TTCCTGATCC GTGCGGTGGC CGGAGCGCAG AGCGTGGCCT GTGACCAGGA GGCGGGCGCG 
CTCTACGTGA TCCAGGAGGG CCTGGAGAAC ACGGGCTGCA CGCTGGTCTT CCTACTGCTC 
TACTACTTCG GCATGGCCAG CTCGCTCTGG TGGGTGGTCC TGACGCTCAC CTGGTTCCTG 
GCTGCCGGGA AGAAATGGGG CCACGAGGCC ATCGAGGCCC ACGGCAGCTA TTTCCACATG 
GCTGCCTGGG GCCTGCCCGC GCTCAAGACC ATCGTCATCC TGACCCTGCG CAAGGTGGCG 
GGTGATGAGC TGACTGGGCT TTGCTACGTG GCCAGCACGG ATGCAGCAGC GCTCACGGGC 
TTCGTGCTGG TGCCCCTCTC TGGCTACCTG GTGCTGGGCA GTAGTTTCCT CCTGACCGGC 
TTCGTGGCCC TCTTCCACAT CCGCAAGATC ATGAAGACGG GCGGCACCAA CACAGAGAAG 
CTGGAGAAGC TCATGGTCAA GATCGGGGTC TTCTCCATCC TCTACACGGT GCCCGCCACC 
TGCGTCATCG TTTGCTATGT CTACGAACGC CTCAACATGG ACTTCTGGCG CCTTCGGGCC 
ACAGAGCAGC CATGCGCAGC GGCCGCGGGG CCCGGAGGCC GGAGGGACTG CTCGCTGCCA 
GGGGGCTCGG TGCCCACCGT GGCGGTCTTC ATGCTCAAAA TTTTCATGTC ACTGGTGGTG 
GGGATCACCA GCGGCGTCTG GGTGTGGAGC TCCAAGACTT TCCAGACCTG GCAGAGCCTG 
TGCTACCGCA AGATAGCAGC TGGCCGGGCC CGGGCCAAGG CCTGCCGCGC CCCCGGGAGC 
TACGGACGTG GCACGCACTG CCACTATAAG GCTCCCACCG TGGTCTTGCA CATGACTAAG 
ACGGACCCCT CTTTGGAGAA CCCCACACAC CTCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Involvement of c-Fos in cell proliferation, migration, and invasion in osteosarcoma cells accompanied by altered expression of Wnt2 and Fzd9.
PloS one12(6)e0180558(2017)
Wang Q,Liu H,Wang Q,Zhou F,Liu Y,Zhang Y,Ding H,Yuan M,Li F,Chen Y

Methylation status of the promoter region of the human frizzled 9 gene in acute myeloid leukemia.
Molecular medicine reports14(2)1339-44(2016 Aug)
Zhang Y,Jiang Q,Kong X,Yang L,Hu W,Lv C,Li Y

A human neurodevelopmental model for Williams syndrome.
Nature536(7616)338-43(2016 08)
Chailangkarn T,Trujillo CA,Freitas BC,Hrvoj-Mihic B,Herai RH,Yu DX,Brown TT,Marchetto MC,Bardy C,McHenry L,Stefanacci L,J?rvinen A,Searcy YM,DeWitt M,Wong W,Lai P,Ard MC,Hanson KL,Romero S,Jacobs B,Dale AM,Dai L,Korenberg JR,Gage FH,Bellugi U,Halgren E,Semendeferi K,Muotri AR

Expression profile of the embryonic markers nanog, OCT-4, SSEA-1, SSEA-4, and frizzled-9 receptor in human periodontal ligament mesenchymal stem cells.
Journal of cellular physiology225(1)123-31(2010 Oct)
Trubiani O,Zalzal SF,Paganelli R,Marchisio M,Giancola R,Pizzicannella J,B?hring HJ,Piattelli M,Caputi S,Nanci A

Sprouty-4 inhibits transformed cell growth, migration and invasion, and epithelial-mesenchymal transition, and is regulated by Wnt7A through PPARgamma in non-small cell lung cancer.
Molecular cancer research : MCR8(6)833-43(2010 Jun)
Tennis MA,Van Scoyk MM,Freeman SV,Vandervest KM,Nemenoff RA,Winn RA

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FZD9 cDNA ORF clone, Homo sapiens(human)

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