FZD7 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	FZD7
Entrez Gene ID	8324
Full Name	frizzled class receptor 7
Synonyms	FzE3
General protein information	Preferred Names frizzled class receptor 7 Names frizzled-7 Frizzled, drosophila, homolog of, 7 frizzled 7, seven transmembrane spanning receptor frizzled family receptor 7 frizzled homolog 7 fz-7 hFz7
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 2 Map Location: 2q33.1
Summary	Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD7 protein contains an N-terminal signal sequence, 10 cysteine residues typical of the cysteine-rich extracellular domain of Fz family members, 7 putative transmembrane domains, and an intracellular C-terminal tail with a PDZ domain-binding motif. FZD7 gene expression may downregulate APC function and enhance beta-catenin-mediated signals in poorly differentiated human esophageal carcinomas. [provided by RefSeq, Jul 2008].
Disorder MIM:	603410

mRNA and Protein(s)

mRNA	Protein	Name
NM_003507.1	NP_003498.1	frizzled-7 precursor

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	FZD7	XP_516034.3
	FZD7	XP_001100283.1
Gallus gallus (chicken)	FZD7	NP_989552.1
Xenopus tropicalis (tropical clawed frog)	fzd7	NP_001016741.1
Canis lupus familiaris (dog)	FZD7	XP_545599.2
Rattus norvegicus (Norway rat)	LOC100360552	NP_001258114.1
Homo sapiens (human)	FZD7	NP_003498.1
Bos taurus (cattle)	FZD7	NP_001137563.1
Mus musculus (house mouse)	Fzd7	NP_032083.3

Gene Ontology

The following FZD7 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the FZD7 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OHu23932	NM_003507.1 Latest version!	Homo sapiens frizzled class receptor 7 (FZD7), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$219.50-$307.30 $439.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

FZD7 ( NM_003507.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_003498.1 Homo sapiens frizzled class receptor 7 (FZD7), mRNA.

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CloneID	OHu23932
Clone ID Related Accession (Same CDS sequence)	NM_003507.1
Accession Version	NM_003507.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1725bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-25
Organism	Homo sapiens(human)
Product	frizzled-7 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AB017365.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript is intronless :: AB017365.1 [ECO:0000345] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGCGGGACC CCGGCGCGGC CGCTCCGCTT TCGTCCCTGG GCCTCTGTGC CCTGGTGCTG 
GCGCTGCTGG GCGCACTGTC CGCGGGCGCC GGGGCGCAGC CGTACCACGG AGAGAAGGGC 
ATCTCCGTGC CGGACCACGG CTTCTGCCAG CCCATCTCCA TCCCGCTGTG CACGGACATC 
GCCTACAACC AGACCATCCT GCCCAACCTG CTGGGCCACA CGAACCAAGA GGACGCGGGC 
CTCGAGGTGC ACCAGTTCTA CCCGCTGGTG AAGGTGCAGT GTTCTCCCGA ACTCCGCTTT 
TTCTTATGCT CCATGTATGC GCCCGTGTGC ACCGTGCTCG ATCAGGCCAT CCCGCCGTGT 
CGTTCTCTGT GCGAGCGCGC CCGCCAGGGC TGCGAGGCGC TCATGAACAA GTTCGGCTTC 
CAGTGGCCCG AGCGGCTGCG CTGCGAGAAC TTCCCGGTGC ACGGTGCGGG CGAGATCTGC 
GTGGGCCAGA ACACGTCGGA CGGCTCCGGG GGCCCAGGCG GCGGCCCCAC TGCCTACCCT 
ACCGCGCCCT ACCTGCCGGA CCTGCCCTTC ACCGCGCTGC CCCCGGGGGC CTCAGATGGC 
AGGGGGCGTC CCGCCTTCCC CTTCTCATGC CCCCGTCAGC TCAAGGTGCC CCCGTACCTG 
GGCTACCGCT TCCTGGGTGA GCGCGATTGT GGCGCCCCGT GCGAACCGGG CCGTGCCAAC 
GGCCTGATGT ACTTTAAGGA GGAGGAGAGG CGCTTCGCCC GCCTCTGGGT GGGCGTGTGG 
TCCGTGCTGT GCTGCGCCTC GACGCTCTTT ACCGTTCTCA CCTACCTGGT GGACATGCGG 
CGCTTCAGCT ACCCAGAGCG GCCCATCATC TTCCTGTCGG GCTGCTACTT CATGGTGGCC 
GTGGCGCACG TGGCCGGCTT CCTTCTAGAG GACCGCGCCG TGTGCGTGGA GCGCTTCTCG 
GACGATGGCT ACCGCACGGT GGCGCAGGGC ACCAAGAAGG AGGGCTGCAC CATCCTCTTC 
ATGGTGCTCT ACTTCTTCGG CATGGCCAGC TCCATCTGGT GGGTCATTCT GTCTCTCACT 
TGGTTCCTGG CGGCCGGCAT GAAGTGGGGC CACGAGGCCA TCGAGGCCAA CTCGCAGTAC 
TTCCACCTGG CCGCGTGGGC CGTGCCCGCC GTCAAGACCA TCACTATCCT GGCCATGGGC 
CAGGTAGACG GGGACCTGCT GAGCGGGGTG TGCTACGTTG GCCTCTCCAG TGTGGACGCG 
CTGCGGGGCT TCGTGCTGGC GCCTCTGTTC GTCTACCTCT TCATAGGCAC GTCCTTCTTG 
CTGGCCGGCT TCGTGTCCCT CTTCCGTATC CGCACCATCA TGAAACACGA CGGCACCAAG 
ACCGAGAAGC TGGAGAAGCT CATGGTGCGC ATCGGCGTCT TCAGCGTGCT CTACACAGTG 
CCCGCCACCA TCGTCCTGGC CTGCTACTTC TACGAGCAGG CCTTCCGCGA GCACTGGGAG 
CGCACCTGGC TCCTGCAGAC GTGCAAGAGC TATGCCGTGC CCTGCCCGCC CGGCCACTTC 
CCGCCCATGA GCCCCGACTT CACCGTCTTC ATGATCAAGT ACCTGATGAC CATGATCGTC 
GGCATCACCA CTGGCTTCTG GATCTGGTCG GGCAAGACCC TGCAGTCGTG GCGCCGCTTC 
TACCACAGAC TTAGCCACAG CAGCAAGGGG GAGACTGCGG TATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_003498.1
CDS	62..1786
Translation	MRDPGAAAPLSSLGLCALVLALLGALSAGAGAQPYHGEKGISVPDHGFCQPISIPLCTDIAYNQTILPNLLGHTNQEDAGLEVHQFYPLVKVQCSPELRFFLCSMYAPVCTVLDQAIPPCRSLCERARQGCEALMNKFGFQWPERLRCENFPVHGAGEICVGQNTSDGSGGPGGGPTAYPTAPYLPDLPFTALPPGASDGRGRPAFPFSCPRQLKVPPYLGYRFLGERDCGAPCEPGRANGLMYFKEEERRFARLWVGVWSVLCCASTLFTVLTYLVDMRRFSYPERPIIFLSGCYFMVAVAHVAGFLLEDRAVCVERFSDDGYRTVAQGTKKEGCTILFMVLYFFGMASSIWWVILSLTWFLAAGMKWGHEAIEANSQYFHLAAWAVPAVKTITILAMGQVDGDLLSGVCYVGLSSVDALRGFVLAPLFVYLFIGTSFLLAGFVSLFRIRTIMKHDGTKTEKLEKLMVRIGVFSVLYTVPATIVLACYFYEQAFREHWERTWLLQTCKSYAVPCPPGHFPPMSPDFTVFMIKYLMTMIVGITTGFWIWSGKTLQSWRRFYHRLSHSSKGETAV

Target ORF information:

RefSeq Version	NM_003507.1
Organism	Homo sapiens(human)
Definition	Homo sapiens frizzled class receptor 7 (FZD7), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_003507.1

ORF Insert Sequence:

ATGCGGGACC CCGGCGCGGC CGCTCCGCTT TCGTCCCTGG GCCTCTGTGC CCTGGTGCTG 
GCGCTGCTGG GCGCACTGTC CGCGGGCGCC GGGGCGCAGC CGTACCACGG AGAGAAGGGC 
ATCTCCGTGC CGGACCACGG CTTCTGCCAG CCCATCTCCA TCCCGCTGTG CACGGACATC 
GCCTACAACC AGACCATCCT GCCCAACCTG CTGGGCCACA CGAACCAAGA GGACGCGGGC 
CTCGAGGTGC ACCAGTTCTA CCCGCTGGTG AAGGTGCAGT GTTCTCCCGA ACTCCGCTTT 
TTCTTATGCT CCATGTATGC GCCCGTGTGC ACCGTGCTCG ATCAGGCCAT CCCGCCGTGT 
CGTTCTCTGT GCGAGCGCGC CCGCCAGGGC TGCGAGGCGC TCATGAACAA GTTCGGCTTC 
CAGTGGCCCG AGCGGCTGCG CTGCGAGAAC TTCCCGGTGC ACGGTGCGGG CGAGATCTGC 
GTGGGCCAGA ACACGTCGGA CGGCTCCGGG GGCCCAGGCG GCGGCCCCAC TGCCTACCCT 
ACCGCGCCCT ACCTGCCGGA CCTGCCCTTC ACCGCGCTGC CCCCGGGGGC CTCAGATGGC 
AGGGGGCGTC CCGCCTTCCC CTTCTCATGC CCCCGTCAGC TCAAGGTGCC CCCGTACCTG 
GGCTACCGCT TCCTGGGTGA GCGCGATTGT GGCGCCCCGT GCGAACCGGG CCGTGCCAAC 
GGCCTGATGT ACTTTAAGGA GGAGGAGAGG CGCTTCGCCC GCCTCTGGGT GGGCGTGTGG 
TCCGTGCTGT GCTGCGCCTC GACGCTCTTT ACCGTTCTCA CCTACCTGGT GGACATGCGG 
CGCTTCAGCT ACCCAGAGCG GCCCATCATC TTCCTGTCGG GCTGCTACTT CATGGTGGCC 
GTGGCGCACG TGGCCGGCTT CCTTCTAGAG GACCGCGCCG TGTGCGTGGA GCGCTTCTCG 
GACGATGGCT ACCGCACGGT GGCGCAGGGC ACCAAGAAGG AGGGCTGCAC CATCCTCTTC 
ATGGTGCTCT ACTTCTTCGG CATGGCCAGC TCCATCTGGT GGGTCATTCT GTCTCTCACT 
TGGTTCCTGG CGGCCGGCAT GAAGTGGGGC CACGAGGCCA TCGAGGCCAA CTCGCAGTAC 
TTCCACCTGG CCGCGTGGGC CGTGCCCGCC GTCAAGACCA TCACTATCCT GGCCATGGGC 
CAGGTAGACG GGGACCTGCT GAGCGGGGTG TGCTACGTTG GCCTCTCCAG TGTGGACGCG 
CTGCGGGGCT TCGTGCTGGC GCCTCTGTTC GTCTACCTCT TCATAGGCAC GTCCTTCTTG 
CTGGCCGGCT TCGTGTCCCT CTTCCGTATC CGCACCATCA TGAAACACGA CGGCACCAAG 
ACCGAGAAGC TGGAGAAGCT CATGGTGCGC ATCGGCGTCT TCAGCGTGCT CTACACAGTG 
CCCGCCACCA TCGTCCTGGC CTGCTACTTC TACGAGCAGG CCTTCCGCGA GCACTGGGAG 
CGCACCTGGC TCCTGCAGAC GTGCAAGAGC TATGCCGTGC CCTGCCCGCC CGGCCACTTC 
CCGCCCATGA GCCCCGACTT CACCGTCTTC ATGATCAAGT ACCTGATGAC CATGATCGTC 
GGCATCACCA CTGGCTTCTG GATCTGGTCG GGCAAGACCC TGCAGTCGTG GCGCCGCTTC 
TACCACAGAC TTAGCCACAG CAGCAAGGGG GAGACTGCGG TATGA