SMC1A cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	SMC1A
Entrez Gene ID	8243
Full Name	structural maintenance of chromosomes 1A
Synonyms	CDLS2,DXS423E,SB1.8,SMC1,SMC1L1,SMC1alpha,SMCB
General protein information	Preferred Names structural maintenance of chromosomes 1A Names structural maintenance of chromosomes protein 1A SMC protein 1A SMC-1-alpha SMC1 (structural maintenance of chromosomes 1, yeast)-like 1 segregation of mitotic chromosomes 1
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: X Map Location: Xp11.22
Summary	Proper cohesion of sister chromatids is a prerequisite for the correct segregation of chromosomes during cell division. The cohesin multiprotein complex is required for sister chromatid cohesion. This complex is composed partly of two structural maintenance of chromosomes (SMC) proteins, SMC3 and either SMC1B or the protein encoded by this gene. Most of the cohesin complexes dissociate from the chromosomes before mitosis, although those complexes at the kinetochore remain. Therefore, the encoded protein is thought to be an important part of functional kinetochores. In addition, this protein interacts with BRCA1 and is phosphorylated by ATM, indicating a potential role for this protein in DNA repair. This gene, which belongs to the SMC gene family, is located in an area of the X-chromosome that escapes X inactivation. Mutations in this gene result in Cornelia de Lange syndrome. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2013].
Disorder MIM:	300040
Disorder Html:	Cornelia de Lange syndrome 2, 300590 (3)

mRNA and Protein(s)

mRNA	Protein	Name
NM_006306.4	NP_006297.2	structural maintenance of chromosomes protein 1A isoform 1
NM_001281463.1	NP_001268392.1	structural maintenance of chromosomes protein 1A isoform 2
NM_006306.3	NP_006297.2	structural maintenance of chromosomes protein 1A isoform 1

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	SMC1A	XP_538049.3
Danio rerio (zebrafish)	smc1a	NP_001155103.1
Schizosaccharomyces pombe (fission yeast)	psm1	NP_596049.2
Mus musculus (house mouse)	Smc1a	NP_062684.2
Caenorhabditis elegans (roundworm)	him-1	NP_001040658.2
	SMC1A	XP_001091228.1
Arabidopsis thaliana (thale cress)	TTN8	NP_001190092.1
Oryza sativa (rice)	Os12g0641500	NP_001067404.1
Danio rerio (zebrafish)	smc1al	NP_997975.2
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP002947	XP_311953.3
Saccharomyces cerevisiae (baker's yeast)	SMC1	NP_116647.1
Kluyveromyces lactis	KLLA0D07502g	XP_453397.1
Eremothecium gossypii	AGOS_AGL023W	NP_986643.1
Homo sapiens (human)	SMC1A	NP_006297.2
Pan troglodytes (chimpanzee)	SMC1A	XP_003954052.1
Bos taurus (cattle)	SMC1A	NP_777039.1
Rattus norvegicus (Norway rat)	Smc1a	NP_113871.1
Gallus gallus (chicken)	SMC1A	NP_989847.1
Drosophila melanogaster (fruit fly)	SMC1	NP_651211.2
Magnaporthe oryzae (rice blast fungus)	MGG_16203	XP_003709622.1
Neurospora crassa	NCU01323	XP_961409.2
Xenopus tropicalis (tropical clawed frog)	LOC100493711	XP_002935560.1

Gene Ontology

The following SMC1A gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the SMC1A cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu21613	NM_006306.4 Latest version!	Homo sapiens structural maintenance of chromosomes 1A (SMC1A), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$274.50-$384.30 $549.00
OHu29161	NM_001281463.1 Latest version!	Homo sapiens structural maintenance of chromosomes 1A (SMC1A), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	20	$643.30 $919.00
View Old Accession Versions >>
OHu21613	NM_006306.3	Homo sapiens structural maintenance of chromosomes 1A (SMC1A), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$274.50-$384.30 $549.00
Hide Old Accession Versions >>

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***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

SMC1A ( NM_006306.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_006297.2 Homo sapiens structural maintenance of chromosomes 1A (SMC1A), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu21613
Clone ID Related Accession (Same CDS sequence)	NM_006306.4 , NM_006306.3
Accession Version	NM_006306.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3702bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-10
Organism	Homo sapiens(human)
Product	structural maintenance of chromosomes protein 1A isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC080185.1, D80000.2 and AC233728.4. On Aug 31, 2019 this sequence version replaced NM_006306.3. Transcript Variant: This variant (1) encodes the longer isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: D80000.2, S78271.1 [ECO:0000332] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on manual assertion, conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGGGTTCC TGAAACTGAT TGAGATTGAG AACTTTAAGT CGTACAAGGG TCGACAGATT 
ATCGGACCAT TTCAGAGGTT CACCGCCATC ATTGGACCCA ATGGCTCTGG TAAGTCAAAT 
CTCATGGATG CCATCAGCTT TGTGCTAGGT GAAAAAACCA GCAACCTGCG GGTAAAGACC 
CTGCGGGACC TGATCCATGG AGCTCCTGTG GGCAAGCCAG CTGCCAACCG GGCCTTTGTC 
AGCATGGTCT ACTCTGAGGA GGGTGCTGAG GACCGTACCT TTGCCCGTGT CATTGTAGGA 
GGTTCTTCTG AGTACAAGAT CAACAACAAA GTGGTCCAAC TACATGAGTA CAGTGAGGAA 
TTAGAGAAGT TGGGCATTCT CATCAAAGCT CGTAACTTCC TCGTTTTCCA GGGTGCTGTG 
GAATCTATTG CCATGAAGAA CCCCAAAGAG AGGACAGCTC TATTTGAAGA GATTAGTCGT 
TCTGGGGAGC TGGCGCAGGA GTATGACAAG CGAAAGAAGG AAATGGTGAA GGCTGAAGAG 
GACACACAGT TTAATTACCA TCGCAAGAAA AATATTGCGG CTGAACGCAA GGAAGCAAAG 
CAGGAGAAAG AAGAGGCTGA CCGGTACCAG CGCCTGAAGG ATGAGGTAGT ACGGGCTCAG 
GTACAGCTGC AGCTCTTTAA GCTTTACCAT AATGAAGTGG AAATTGAGAA GCTCAACAAG 
GAACTGGCCT CAAAGAACAA GGAGATCGAG AAGGACAAGA AGCGTATGGA CAAGGTGGAG 
GATGAACTGA AGGAGAAGAA GAAGGAGCTG GGCAAAATGA TGCGGGAGCA GCAGCAGATT 
GAGAAGGAGA TCAAGGAGAA GGACTCAGAA TTGAACCAGA AGCGGCCTCA GTACATCAAA 
GCCAAGGAGA ACACCTCCCA CAAAATCAAG AAGCTGGAAG CAGCCAAGAA GTCTCTGCAG 
AATGCTCAGA AGCACTACAA GAAGCGTAAA GGTGACATGG ATGAGCTGGA GAAGGAGATG 
CTGTCAGTGG AGAAGGCTCG GCAGGAGTTT GAAGAACGGA TGGAAGAAGA GAGTCAGAGT 
CAGGGCAGAG ATTTGACGTT GGAGGAGAAT CAGGTGAAGA AATACCACCG GTTGAAAGAA 
GAAGCCAGCA AGAGAGCAGC TACCCTGGCC CAGGAGCTGG AGAAATTCAA TCGAGACCAG 
AAAGCTGACC AGGACCGTCT GGATCTGGAA GAACGGAAGA AAGTAGAGAC AGAGGCCAAG 
ATCAAGCAAA AGCTGCGGGA AATTGAAGAG AATCAGAAGC GGATTGAGAA ACTGGAGGAA 
TACATCACCA CTAGCAAGCA GTCCCTAGAA GAGCAGAAGA AGCTAGAGGG GGAGCTGACA 
GAGGAGGTGG AGATGGCCAA GCGGCGTATT GATGAAATCA ATAAGGAGCT GAACCAGGTG 
ATGGAGCAGC TAGGGGATGC CCGCATCGAC CGCCAGGAGA GCAGCCGCCA GCAGCGAAAG 
GCAGAGATAA TGGAAAGCAT CAAGCGCCTT TACCCTGGCT CTGTGTACGG CCGCCTCATT 
GACCTATGCC AGCCCACACA AAAGAAGTAT CAGATTGCTG TAACCAAGGT TTTGGGCAAG 
AACATGGATG CCATTATTGT GGACTCGGAG AAGACAGGCC GGGACTGTAT TCAGTATATC 
AAGGAGCAGC GTGGGGAGCC TGAGACCTTC TTGCCTCTTG ACTACCTGGA GGTGAAGCCT 
ACAGATGAGA AACTCCGGGA GCTGAAGGGG GCCAAGCTAG TGATTGATGT GATTCGCTAT 
GAGCCACCTC ATATCAAAAA GGCCCTGCAG TATGCTTGTG GCAATGCCCT TGTCTGTGAC 
AACGTGGAAG ATGCCCGCCG CATTGCCTTT GGAGGCCACC AGCGCCACAA GACAGTGGCA 
CTGGATGGAA CCCTATTCCA GAAGTCAGGA GTGATCTCTG GTGGGGCCAG TGACCTGAAG 
GCCAAGGCAC GGCGCTGGGA TGAGAAAGCA GTAGACAAGT TGAAAGAGAA GAAGGAGCGC 
TTGACAGAGG AGCTGAAAGA GCAGATGAAG GCAAAACGGA AAGAGGCAGA GCTGCGTCAG 
GTGCAGTCTC AGGCCCATGG ACTGCAGATG CGGCTCAAGT ACTCCCAGAG TGACCTAGAA 
CAGACCAAGA CACGACATCT AGCCCTGAAT CTGCAGGAAA AATCCAAGCT GGAGAGTGAG 
CTAGCCAACT TTGGGCCTCG CATTAATGAT ATCAAGAGGA TCATTCAGAG CCGAGAGAGG 
GAAATGAAAG ACTTGAAGGA GAAGATGAAC CAGGTAGAGG ATGAGGTGTT TGAAGAGTTT 
TGTCGGGAGA TTGGTGTGCG CAACATCCGG GAGTTTGAGG AAGAAAAGGT GAAACGGCAG 
AATGAAATCG CCAAGAAGCG TTTGGAGTTT GAGAATCAGA AGACTCGCTT GGGCATTCAG 
TTGGATTTTG AAAAGAACCA ACTGAAGGAG GACCAAGATA AAGTACACAT GTGGGAGCAG 
ACAGTGAAAA AAGATGAAAA TGAGATAGAA AAGCTCAAAA AGGAGGAACA AAGACACATG 
AAGATCATAG ATGAGACCAT GGCTCAGCTA CAAGACCTGA AGAATCAGCA TCTGGCCAAG 
AAGTCGGAAG TGAATGACAA GAATCATGAG ATGGAGGAGA TTCGTAAGAA ACTCGGGGGC 
GCCAACAAGG AAATGACCCA TTTACAGAAG GAGGTGACAG CCATTGAGAC CAAGCTTGAA 
CAGAAGCGCA GTGACCGTCA CAACTTGCTA CAGGCCTGTA AGATGCAGGA CATTAAGTTG 
CCACTGTCAA AAGGCACCAT GGATGATATT AGTCAGGAAG AGGGTAGCTC CCAGGGGGAG 
GACTCAGTGA GTGGTTCACA GAGAATTTCC AGTATCTATG CACGAGAGGC CCTCATTGAG 
ATTGACTACG GTGATCTGTG TGAGGATCTG AAGGATGCCC AGGCTGAGGA AGAGATCAAG 
CAAGAGATGA ACACACTGCA GCAGAAGCTG AATGAGCAGC AGAGTGTGCT TCAGCGTATT 
GCCGCCCCCA ACATGAAGGC CATGGAAAAG CTGGAAAGTG TCCGAGACAA GTTCCAGGAG 
ACCTCAGATG AGTTTGAAGC AGCCCGAAAG CGAGCAAAGA AGGCCAAGCA GGCATTCGAA 
CAGATCAAGA AGGAGCGCTT TGACCGCTTC AATGCTTGTT TTGAATCTGT GGCTACCAAC 
ATTGATGAGA TCTATAAGGC CCTGTCCCGC AATAGCAGTG CCCAGGCATT CCTGGGCCCT 
GAGAACCCTG AAGAGCCCTA CTTGGATGGC ATCAACTACA ACTGTGTGGC TCCTGGGAAA 
CGCTTCCGGC CTATGGACAA CTTGTCAGGC GGGGAGAAGA CAGTGGCAGC TCTGGCCCTG 
CTCTTTGCCA TCCACAGCTA CAAGCCAGCC CCCTTCTTCG TCCTGGATGA GATTGATGCT 
GCCTTGGATA ACACCAACAT TGGCAAGGTG GCAAATTACA TCAAGGAGCA GTCGACTTGC 
AACTTCCAGG CCATCGTCAT CTCTCTCAAG GAGGAGTTCT ACACCAAGGC CGAGAGCCTC 
ATTGGAGTCT ATCCTGAGCA AGGGGACTGT GTGATCAGCA AAGTCCTGAC CTTCGACCTC 
ACCAAGTACC CAGATGCCAA CCCCAACCCC AATGAGCAGT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_006297.2
CDS	55..3756
Translation	MGFLKLIEIENFKSYKGRQIIGPFQRFTAIIGPNGSGKSNLMDAISFVLGEKTSNLRVKTLRDLIHGAPVGKPAANRAFVSMVYSEEGAEDRTFARVIVGGSSEYKINNKVVQLHEYSEELEKLGILIKARNFLVFQGAVESIAMKNPKERTALFEEISRSGELAQEYDKRKKEMVKAEEDTQFNYHRKKNIAAERKEAKQEKEEADRYQRLKDEVVRAQVQLQLFKLYHNEVEIEKLNKELASKNKEIEKDKKRMDKVEDELKEKKKELGKMMREQQQIEKEIKEKDSELNQKRPQYIKAKENTSHKIKKLEAAKKSLQNAQKHYKKRKGDMDELEKEMLSVEKARQEFEERMEEESQSQGRDLTLEENQVKKYHRLKEEASKRAATLAQELEKFNRDQKADQDRLDLEERKKVETEAKIKQKLREIEENQKRIEKLEEYITTSKQSLEEQKKLEGELTEEVEMAKRRIDEINKELNQVMEQLGDARIDRQESSRQQRKAEIMESIKRLYPGSVYGRLIDLCQPTQKKYQIAVTKVLGKNMDAIIVDSEKTGRDCIQYIKEQRGEPETFLPLDYLEVKPTDEKLRELKGAKLVIDVIRYEPPHIKKALQYACGNALVCDNVEDARRIAFGGHQRHKTVALDGTLFQKSGVISGGASDLKAKARRWDEKAVDKLKEKKERLTEELKEQMKAKRKEAELRQVQSQAHGLQMRLKYSQSDLEQTKTRHLALNLQEKSKLESELANFGPRINDIKRIIQSREREMKDLKEKMNQVEDEVFEEFCREIGVRNIREFEEEKVKRQNEIAKKRLEFENQKTRLGIQLDFEKNQLKEDQDKVHMWEQTVKKDENEIEKLKKEEQRHMKIIDETMAQLQDLKNQHLAKKSEVNDKNHEMEEIRKKLGGANKEMTHLQKEVTAIETKLEQKRSDRHNLLQACKMQDIKLPLSKGTMDDISQEEGSSQGEDSVSGSQRISSIYAREALIEIDYGDLCEDLKDAQAEEEIKQEMNTLQQKLNEQQSVLQRIAAPNMKAMEKLESVRDKFQETSDEFEAARKRAKKAKQAFEQIKKERFDRFNACFESVATNIDEIYKALSRNSSAQAFLGPENPEEPYLDGINYNCVAPGKRFRPMDNLSGGEKTVAALALLFAIHSYKPAPFFVLDEIDAALDNTNIGKVANYIKEQSTCNFQAIVISLKEEFYTKAESLIGVYPEQGDCVISKVLTFDLTKYPDANPNPNEQ

Target ORF information:

RefSeq Version	NM_006306.4
Organism	Homo sapiens(human)
Definition	Homo sapiens structural maintenance of chromosomes 1A (SMC1A), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_006306.4

ORF Insert Sequence:

ATGGGGTTCC TGAAACTGAT TGAGATTGAG AACTTTAAGT CGTACAAGGG TCGACAGATT 
ATCGGACCAT TTCAGAGGTT CACCGCCATC ATTGGACCCA ATGGCTCTGG TAAGTCAAAT 
CTCATGGATG CCATCAGCTT TGTGCTAGGT GAAAAAACCA GCAACCTGCG GGTAAAGACC 
CTGCGGGACC TGATCCATGG AGCTCCTGTG GGCAAGCCAG CTGCCAACCG GGCCTTTGTC 
AGCATGGTCT ACTCTGAGGA GGGTGCTGAG GACCGTACCT TTGCCCGTGT CATTGTAGGA 
GGTTCTTCTG AGTACAAGAT CAACAACAAA GTGGTCCAAC TACATGAGTA CAGTGAGGAA 
TTAGAGAAGT TGGGCATTCT CATCAAAGCT CGTAACTTCC TCGTTTTCCA GGGTGCTGTG 
GAATCTATTG CCATGAAGAA CCCCAAAGAG AGGACAGCTC TATTTGAAGA GATTAGTCGT 
TCTGGGGAGC TGGCGCAGGA GTATGACAAG CGAAAGAAGG AAATGGTGAA GGCTGAAGAG 
GACACACAGT TTAATTACCA TCGCAAGAAA AATATTGCGG CTGAACGCAA GGAAGCAAAG 
CAGGAGAAAG AAGAGGCTGA CCGGTACCAG CGCCTGAAGG ATGAGGTAGT ACGGGCTCAG 
GTACAGCTGC AGCTCTTTAA GCTTTACCAT AATGAAGTGG AAATTGAGAA GCTCAACAAG 
GAACTGGCCT CAAAGAACAA GGAGATCGAG AAGGACAAGA AGCGTATGGA CAAGGTGGAG 
GATGAACTGA AGGAGAAGAA GAAGGAGCTG GGCAAAATGA TGCGGGAGCA GCAGCAGATT 
GAGAAGGAGA TCAAGGAGAA GGACTCAGAA TTGAACCAGA AGCGGCCTCA GTACATCAAA 
GCCAAGGAGA ACACCTCCCA CAAAATCAAG AAGCTGGAAG CAGCCAAGAA GTCTCTGCAG 
AATGCTCAGA AGCACTACAA GAAGCGTAAA GGTGACATGG ATGAGCTGGA GAAGGAGATG 
CTGTCAGTGG AGAAGGCTCG GCAGGAGTTT GAAGAACGGA TGGAAGAAGA GAGTCAGAGT 
CAGGGCAGAG ATTTGACGTT GGAGGAGAAT CAGGTGAAGA AATACCACCG GTTGAAAGAA 
GAAGCCAGCA AGAGAGCAGC TACCCTGGCC CAGGAGCTGG AGAAATTCAA TCGAGACCAG 
AAAGCTGACC AGGACCGTCT GGATCTGGAA GAACGGAAGA AAGTAGAGAC AGAGGCCAAG 
ATCAAGCAAA AGCTGCGGGA AATTGAAGAG AATCAGAAGC GGATTGAGAA ACTGGAGGAA 
TACATCACCA CTAGCAAGCA GTCCCTAGAA GAGCAGAAGA AGCTAGAGGG GGAGCTGACA 
GAGGAGGTGG AGATGGCCAA GCGGCGTATT GATGAAATCA ATAAGGAGCT GAACCAGGTG 
ATGGAGCAGC TAGGGGATGC CCGCATCGAC CGCCAGGAGA GCAGCCGCCA GCAGCGAAAG 
GCAGAGATAA TGGAAAGCAT CAAGCGCCTT TACCCTGGCT CTGTGTACGG CCGCCTCATT 
GACCTATGCC AGCCCACACA AAAGAAGTAT CAGATTGCTG TAACCAAGGT TTTGGGCAAG 
AACATGGATG CCATTATTGT GGACTCGGAG AAGACAGGCC GGGACTGTAT TCAGTATATC 
AAGGAGCAGC GTGGGGAGCC TGAGACCTTC TTGCCTCTTG ACTACCTGGA GGTGAAGCCT 
ACAGATGAGA AACTCCGGGA GCTGAAGGGG GCCAAGCTAG TGATTGATGT GATTCGCTAT 
GAGCCACCTC ATATCAAAAA GGCCCTGCAG TATGCTTGTG GCAATGCCCT TGTCTGTGAC 
AACGTGGAAG ATGCCCGCCG CATTGCCTTT GGAGGCCACC AGCGCCACAA GACAGTGGCA 
CTGGATGGAA CCCTATTCCA GAAGTCAGGA GTGATCTCTG GTGGGGCCAG TGACCTGAAG 
GCCAAGGCAC GGCGCTGGGA TGAGAAAGCA GTAGACAAGT TGAAAGAGAA GAAGGAGCGC 
TTGACAGAGG AGCTGAAAGA GCAGATGAAG GCAAAACGGA AAGAGGCAGA GCTGCGTCAG 
GTGCAGTCTC AGGCCCATGG ACTGCAGATG CGGCTCAAGT ACTCCCAGAG TGACCTAGAA 
CAGACCAAGA CACGACATCT AGCCCTGAAT CTGCAGGAAA AATCCAAGCT GGAGAGTGAG 
CTAGCCAACT TTGGGCCTCG CATTAATGAT ATCAAGAGGA TCATTCAGAG CCGAGAGAGG 
GAAATGAAAG ACTTGAAGGA GAAGATGAAC CAGGTAGAGG ATGAGGTGTT TGAAGAGTTT 
TGTCGGGAGA TTGGTGTGCG CAACATCCGG GAGTTTGAGG AAGAAAAGGT GAAACGGCAG 
AATGAAATCG CCAAGAAGCG TTTGGAGTTT GAGAATCAGA AGACTCGCTT GGGCATTCAG 
TTGGATTTTG AAAAGAACCA ACTGAAGGAG GACCAAGATA AAGTACACAT GTGGGAGCAG 
ACAGTGAAAA AAGATGAAAA TGAGATAGAA AAGCTCAAAA AGGAGGAACA AAGACACATG 
AAGATCATAG ATGAGACCAT GGCTCAGCTA CAAGACCTGA AGAATCAGCA TCTGGCCAAG 
AAGTCGGAAG TGAATGACAA GAATCATGAG ATGGAGGAGA TTCGTAAGAA ACTCGGGGGC 
GCCAACAAGG AAATGACCCA TTTACAGAAG GAGGTGACAG CCATTGAGAC CAAGCTTGAA 
CAGAAGCGCA GTGACCGTCA CAACTTGCTA CAGGCCTGTA AGATGCAGGA CATTAAGTTG 
CCACTGTCAA AAGGCACCAT GGATGATATT AGTCAGGAAG AGGGTAGCTC CCAGGGGGAG 
GACTCAGTGA GTGGTTCACA GAGAATTTCC AGTATCTATG CACGAGAGGC CCTCATTGAG 
ATTGACTACG GTGATCTGTG TGAGGATCTG AAGGATGCCC AGGCTGAGGA AGAGATCAAG 
CAAGAGATGA ACACACTGCA GCAGAAGCTG AATGAGCAGC AGAGTGTGCT TCAGCGTATT 
GCCGCCCCCA ACATGAAGGC CATGGAAAAG CTGGAAAGTG TCCGAGACAA GTTCCAGGAG 
ACCTCAGATG AGTTTGAAGC AGCCCGAAAG CGAGCAAAGA AGGCCAAGCA GGCATTCGAA 
CAGATCAAGA AGGAGCGCTT TGACCGCTTC AATGCTTGTT TTGAATCTGT GGCTACCAAC 
ATTGATGAGA TCTATAAGGC CCTGTCCCGC AATAGCAGTG CCCAGGCATT CCTGGGCCCT 
GAGAACCCTG AAGAGCCCTA CTTGGATGGC ATCAACTACA ACTGTGTGGC TCCTGGGAAA 
CGCTTCCGGC CTATGGACAA CTTGTCAGGC GGGGAGAAGA CAGTGGCAGC TCTGGCCCTG 
CTCTTTGCCA TCCACAGCTA CAAGCCAGCC CCCTTCTTCG TCCTGGATGA GATTGATGCT 
GCCTTGGATA ACACCAACAT TGGCAAGGTG GCAAATTACA TCAAGGAGCA GTCGACTTGC 
AACTTCCAGG CCATCGTCAT CTCTCTCAAG GAGGAGTTCT ACACCAAGGC CGAGAGCCTC 
ATTGGAGTCT ATCCTGAGCA AGGGGACTGT GTGATCAGCA AAGTCCTGAC CTTCGACCTC 
ACCAAGTACC CAGATGCCAA CCCCAACCCC AATGAGCAGT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SMC1A ( NM_006306.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_006297.2 Homo sapiens structural maintenance of chromosomes 1A (SMC1A), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu21613
Clone ID Related Accession (Same CDS sequence)	NM_006306.4 , NM_006306.3
Accession Version	NM_006306.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3702bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-06-17
Organism	Homo sapiens(human)
Product	structural maintenance of chromosomes protein 1A isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BP312805.1, BC080185.1, D80000.2 and AC233728.4. This sequence is a reference standard in the RefSeqGene project. On Jul 27, 2013 this sequence version replaced NM_006306.2. Transcript Variant: This variant (1) encodes the longer isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803616.212109.1, SRR1660803.37658.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGGGTTCC TGAAACTGAT TGAGATTGAG AACTTTAAGT CGTACAAGGG TCGACAGATT 
ATCGGACCAT TTCAGAGGTT CACCGCCATC ATTGGACCCA ATGGCTCTGG TAAGTCAAAT 
CTCATGGATG CCATCAGCTT TGTGCTAGGT GAAAAAACCA GCAACCTGCG GGTAAAGACC 
CTGCGGGACC TGATCCATGG AGCTCCTGTG GGCAAGCCAG CTGCCAACCG GGCCTTTGTC 
AGCATGGTCT ACTCTGAGGA GGGTGCTGAG GACCGTACCT TTGCCCGTGT CATTGTAGGA 
GGTTCTTCTG AGTACAAGAT CAACAACAAA GTGGTCCAAC TACATGAGTA CAGTGAGGAA 
TTAGAGAAGT TGGGCATTCT CATCAAAGCT CGTAACTTCC TCGTTTTCCA GGGTGCTGTG 
GAATCTATTG CCATGAAGAA CCCCAAAGAG AGGACAGCTC TATTTGAAGA GATTAGTCGT 
TCTGGGGAGC TGGCGCAGGA GTATGACAAG CGAAAGAAGG AAATGGTGAA GGCTGAAGAG 
GACACACAGT TTAATTACCA TCGCAAGAAA AATATTGCGG CTGAACGCAA GGAAGCAAAG 
CAGGAGAAAG AAGAGGCTGA CCGGTACCAG CGCCTGAAGG ATGAGGTAGT ACGGGCTCAG 
GTACAGCTGC AGCTCTTTAA GCTTTACCAT AATGAAGTGG AAATTGAGAA GCTCAACAAG 
GAACTGGCCT CAAAGAACAA GGAGATCGAG AAGGACAAGA AGCGTATGGA CAAGGTGGAG 
GATGAACTGA AGGAGAAGAA GAAGGAGCTG GGCAAAATGA TGCGGGAGCA GCAGCAGATT 
GAGAAGGAGA TCAAGGAGAA GGACTCAGAA TTGAACCAGA AGCGGCCTCA GTACATCAAA 
GCCAAGGAGA ACACCTCCCA CAAAATCAAG AAGCTGGAAG CAGCCAAGAA GTCTCTGCAG 
AATGCTCAGA AGCACTACAA GAAGCGTAAA GGTGACATGG ATGAGCTGGA GAAGGAGATG 
CTGTCAGTGG AGAAGGCTCG GCAGGAGTTT GAAGAACGGA TGGAAGAAGA GAGTCAGAGT 
CAGGGCAGAG ATTTGACGTT GGAGGAGAAT CAGGTGAAGA AATACCACCG GTTGAAAGAA 
GAAGCCAGCA AGAGAGCAGC TACCCTGGCC CAGGAGCTGG AGAAATTCAA TCGAGACCAG 
AAAGCTGACC AGGACCGTCT GGATCTGGAA GAACGGAAGA AAGTAGAGAC AGAGGCCAAG 
ATCAAGCAAA AGCTGCGGGA AATTGAAGAG AATCAGAAGC GGATTGAGAA ACTGGAGGAA 
TACATCACCA CTAGCAAGCA GTCCCTAGAA GAGCAGAAGA AGCTAGAGGG GGAGCTGACA 
GAGGAGGTGG AGATGGCCAA GCGGCGTATT GATGAAATCA ATAAGGAGCT GAACCAGGTG 
ATGGAGCAGC TAGGGGATGC CCGCATCGAC CGCCAGGAGA GCAGCCGCCA GCAGCGAAAG 
GCAGAGATAA TGGAAAGCAT CAAGCGCCTT TACCCTGGCT CTGTGTACGG CCGCCTCATT 
GACCTATGCC AGCCCACACA AAAGAAGTAT CAGATTGCTG TAACCAAGGT TTTGGGCAAG 
AACATGGATG CCATTATTGT GGACTCGGAG AAGACAGGCC GGGACTGTAT TCAGTATATC 
AAGGAGCAGC GTGGGGAGCC TGAGACCTTC TTGCCTCTTG ACTACCTGGA GGTGAAGCCT 
ACAGATGAGA AACTCCGGGA GCTGAAGGGG GCCAAGCTAG TGATTGATGT GATTCGCTAT 
GAGCCACCTC ATATCAAAAA GGCCCTGCAG TATGCTTGTG GCAATGCCCT TGTCTGTGAC 
AACGTGGAAG ATGCCCGCCG CATTGCCTTT GGAGGCCACC AGCGCCACAA GACAGTGGCA 
CTGGATGGAA CCCTATTCCA GAAGTCAGGA GTGATCTCTG GTGGGGCCAG TGACCTGAAG 
GCCAAGGCAC GGCGCTGGGA TGAGAAAGCA GTAGACAAGT TGAAAGAGAA GAAGGAGCGC 
TTGACAGAGG AGCTGAAAGA GCAGATGAAG GCAAAACGGA AAGAGGCAGA GCTGCGTCAG 
GTGCAGTCTC AGGCCCATGG ACTGCAGATG CGGCTCAAGT ACTCCCAGAG TGACCTAGAA 
CAGACCAAGA CACGACATCT AGCCCTGAAT CTGCAGGAAA AATCCAAGCT GGAGAGTGAG 
CTAGCCAACT TTGGGCCTCG CATTAATGAT ATCAAGAGGA TCATTCAGAG CCGAGAGAGG 
GAAATGAAAG ACTTGAAGGA GAAGATGAAC CAGGTAGAGG ATGAGGTGTT TGAAGAGTTT 
TGTCGGGAGA TTGGTGTGCG CAACATCCGG GAGTTTGAGG AAGAAAAGGT GAAACGGCAG 
AATGAAATCG CCAAGAAGCG TTTGGAGTTT GAGAATCAGA AGACTCGCTT GGGCATTCAG 
TTGGATTTTG AAAAGAACCA ACTGAAGGAG GACCAAGATA AAGTACACAT GTGGGAGCAG 
ACAGTGAAAA AAGATGAAAA TGAGATAGAA AAGCTCAAAA AGGAGGAACA AAGACACATG 
AAGATCATAG ATGAGACCAT GGCTCAGCTA CAAGACCTGA AGAATCAGCA TCTGGCCAAG 
AAGTCGGAAG TGAATGACAA GAATCATGAG ATGGAGGAGA TTCGTAAGAA ACTCGGGGGC 
GCCAACAAGG AAATGACCCA TTTACAGAAG GAGGTGACAG CCATTGAGAC CAAGCTTGAA 
CAGAAGCGCA GTGACCGTCA CAACTTGCTA CAGGCCTGTA AGATGCAGGA CATTAAGTTG 
CCACTGTCAA AAGGCACCAT GGATGATATT AGTCAGGAAG AGGGTAGCTC CCAGGGGGAG 
GACTCAGTGA GTGGTTCACA GAGAATTTCC AGTATCTATG CACGAGAGGC CCTCATTGAG 
ATTGACTACG GTGATCTGTG TGAGGATCTG AAGGATGCCC AGGCTGAGGA AGAGATCAAG 
CAAGAGATGA ACACACTGCA GCAGAAGCTG AATGAGCAGC AGAGTGTGCT TCAGCGTATT 
GCCGCCCCCA ACATGAAGGC CATGGAAAAG CTGGAAAGTG TCCGAGACAA GTTCCAGGAG 
ACCTCAGATG AGTTTGAAGC AGCCCGAAAG CGAGCAAAGA AGGCCAAGCA GGCATTCGAA 
CAGATCAAGA AGGAGCGCTT TGACCGCTTC AATGCTTGTT TTGAATCTGT GGCTACCAAC 
ATTGATGAGA TCTATAAGGC CCTGTCCCGC AATAGCAGTG CCCAGGCATT CCTGGGCCCT 
GAGAACCCTG AAGAGCCCTA CTTGGATGGC ATCAACTACA ACTGTGTGGC TCCTGGGAAA 
CGCTTCCGGC CTATGGACAA CTTGTCAGGC GGGGAGAAGA CAGTGGCAGC TCTGGCCCTG 
CTCTTTGCCA TCCACAGCTA CAAGCCAGCC CCCTTCTTCG TCCTGGATGA GATTGATGCT 
GCCTTGGATA ACACCAACAT TGGCAAGGTG GCAAATTACA TCAAGGAGCA GTCGACTTGC 
AACTTCCAGG CCATCGTCAT CTCTCTCAAG GAGGAGTTCT ACACCAAGGC CGAGAGCCTC 
ATTGGAGTCT ATCCTGAGCA AGGGGACTGT GTGATCAGCA AAGTCCTGAC CTTCGACCTC 
ACCAAGTACC CAGATGCCAA CCCCAACCCC AATGAGCAGT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_006297.2
CDS	129..3830
Translation	MGFLKLIEIENFKSYKGRQIIGPFQRFTAIIGPNGSGKSNLMDAISFVLGEKTSNLRVKTLRDLIHGAPVGKPAANRAFVSMVYSEEGAEDRTFARVIVGGSSEYKINNKVVQLHEYSEELEKLGILIKARNFLVFQGAVESIAMKNPKERTALFEEISRSGELAQEYDKRKKEMVKAEEDTQFNYHRKKNIAAERKEAKQEKEEADRYQRLKDEVVRAQVQLQLFKLYHNEVEIEKLNKELASKNKEIEKDKKRMDKVEDELKEKKKELGKMMREQQQIEKEIKEKDSELNQKRPQYIKAKENTSHKIKKLEAAKKSLQNAQKHYKKRKGDMDELEKEMLSVEKARQEFEERMEEESQSQGRDLTLEENQVKKYHRLKEEASKRAATLAQELEKFNRDQKADQDRLDLEERKKVETEAKIKQKLREIEENQKRIEKLEEYITTSKQSLEEQKKLEGELTEEVEMAKRRIDEINKELNQVMEQLGDARIDRQESSRQQRKAEIMESIKRLYPGSVYGRLIDLCQPTQKKYQIAVTKVLGKNMDAIIVDSEKTGRDCIQYIKEQRGEPETFLPLDYLEVKPTDEKLRELKGAKLVIDVIRYEPPHIKKALQYACGNALVCDNVEDARRIAFGGHQRHKTVALDGTLFQKSGVISGGASDLKAKARRWDEKAVDKLKEKKERLTEELKEQMKAKRKEAELRQVQSQAHGLQMRLKYSQSDLEQTKTRHLALNLQEKSKLESELANFGPRINDIKRIIQSREREMKDLKEKMNQVEDEVFEEFCREIGVRNIREFEEEKVKRQNEIAKKRLEFENQKTRLGIQLDFEKNQLKEDQDKVHMWEQTVKKDENEIEKLKKEEQRHMKIIDETMAQLQDLKNQHLAKKSEVNDKNHEMEEIRKKLGGANKEMTHLQKEVTAIETKLEQKRSDRHNLLQACKMQDIKLPLSKGTMDDISQEEGSSQGEDSVSGSQRISSIYAREALIEIDYGDLCEDLKDAQAEEEIKQEMNTLQQKLNEQQSVLQRIAAPNMKAMEKLESVRDKFQETSDEFEAARKRAKKAKQAFEQIKKERFDRFNACFESVATNIDEIYKALSRNSSAQAFLGPENPEEPYLDGINYNCVAPGKRFRPMDNLSGGEKTVAALALLFAIHSYKPAPFFVLDEIDAALDNTNIGKVANYIKEQSTCNFQAIVISLKEEFYTKAESLIGVYPEQGDCVISKVLTFDLTKYPDANPNPNEQ

Target ORF information:

RefSeq Version	NM_006306.3
Organism	Homo sapiens(human)
Definition	Homo sapiens structural maintenance of chromosomes 1A (SMC1A), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_006306.3

ORF Insert Sequence:

ATGGGGTTCC TGAAACTGAT TGAGATTGAG AACTTTAAGT CGTACAAGGG TCGACAGATT 
ATCGGACCAT TTCAGAGGTT CACCGCCATC ATTGGACCCA ATGGCTCTGG TAAGTCAAAT 
CTCATGGATG CCATCAGCTT TGTGCTAGGT GAAAAAACCA GCAACCTGCG GGTAAAGACC 
CTGCGGGACC TGATCCATGG AGCTCCTGTG GGCAAGCCAG CTGCCAACCG GGCCTTTGTC 
AGCATGGTCT ACTCTGAGGA GGGTGCTGAG GACCGTACCT TTGCCCGTGT CATTGTAGGA 
GGTTCTTCTG AGTACAAGAT CAACAACAAA GTGGTCCAAC TACATGAGTA CAGTGAGGAA 
TTAGAGAAGT TGGGCATTCT CATCAAAGCT CGTAACTTCC TCGTTTTCCA GGGTGCTGTG 
GAATCTATTG CCATGAAGAA CCCCAAAGAG AGGACAGCTC TATTTGAAGA GATTAGTCGT 
TCTGGGGAGC TGGCGCAGGA GTATGACAAG CGAAAGAAGG AAATGGTGAA GGCTGAAGAG 
GACACACAGT TTAATTACCA TCGCAAGAAA AATATTGCGG CTGAACGCAA GGAAGCAAAG 
CAGGAGAAAG AAGAGGCTGA CCGGTACCAG CGCCTGAAGG ATGAGGTAGT ACGGGCTCAG 
GTACAGCTGC AGCTCTTTAA GCTTTACCAT AATGAAGTGG AAATTGAGAA GCTCAACAAG 
GAACTGGCCT CAAAGAACAA GGAGATCGAG AAGGACAAGA AGCGTATGGA CAAGGTGGAG 
GATGAACTGA AGGAGAAGAA GAAGGAGCTG GGCAAAATGA TGCGGGAGCA GCAGCAGATT 
GAGAAGGAGA TCAAGGAGAA GGACTCAGAA TTGAACCAGA AGCGGCCTCA GTACATCAAA 
GCCAAGGAGA ACACCTCCCA CAAAATCAAG AAGCTGGAAG CAGCCAAGAA GTCTCTGCAG 
AATGCTCAGA AGCACTACAA GAAGCGTAAA GGTGACATGG ATGAGCTGGA GAAGGAGATG 
CTGTCAGTGG AGAAGGCTCG GCAGGAGTTT GAAGAACGGA TGGAAGAAGA GAGTCAGAGT 
CAGGGCAGAG ATTTGACGTT GGAGGAGAAT CAGGTGAAGA AATACCACCG GTTGAAAGAA 
GAAGCCAGCA AGAGAGCAGC TACCCTGGCC CAGGAGCTGG AGAAATTCAA TCGAGACCAG 
AAAGCTGACC AGGACCGTCT GGATCTGGAA GAACGGAAGA AAGTAGAGAC AGAGGCCAAG 
ATCAAGCAAA AGCTGCGGGA AATTGAAGAG AATCAGAAGC GGATTGAGAA ACTGGAGGAA 
TACATCACCA CTAGCAAGCA GTCCCTAGAA GAGCAGAAGA AGCTAGAGGG GGAGCTGACA 
GAGGAGGTGG AGATGGCCAA GCGGCGTATT GATGAAATCA ATAAGGAGCT GAACCAGGTG 
ATGGAGCAGC TAGGGGATGC CCGCATCGAC CGCCAGGAGA GCAGCCGCCA GCAGCGAAAG 
GCAGAGATAA TGGAAAGCAT CAAGCGCCTT TACCCTGGCT CTGTGTACGG CCGCCTCATT 
GACCTATGCC AGCCCACACA AAAGAAGTAT CAGATTGCTG TAACCAAGGT TTTGGGCAAG 
AACATGGATG CCATTATTGT GGACTCGGAG AAGACAGGCC GGGACTGTAT TCAGTATATC 
AAGGAGCAGC GTGGGGAGCC TGAGACCTTC TTGCCTCTTG ACTACCTGGA GGTGAAGCCT 
ACAGATGAGA AACTCCGGGA GCTGAAGGGG GCCAAGCTAG TGATTGATGT GATTCGCTAT 
GAGCCACCTC ATATCAAAAA GGCCCTGCAG TATGCTTGTG GCAATGCCCT TGTCTGTGAC 
AACGTGGAAG ATGCCCGCCG CATTGCCTTT GGAGGCCACC AGCGCCACAA GACAGTGGCA 
CTGGATGGAA CCCTATTCCA GAAGTCAGGA GTGATCTCTG GTGGGGCCAG TGACCTGAAG 
GCCAAGGCAC GGCGCTGGGA TGAGAAAGCA GTAGACAAGT TGAAAGAGAA GAAGGAGCGC 
TTGACAGAGG AGCTGAAAGA GCAGATGAAG GCAAAACGGA AAGAGGCAGA GCTGCGTCAG 
GTGCAGTCTC AGGCCCATGG ACTGCAGATG CGGCTCAAGT ACTCCCAGAG TGACCTAGAA 
CAGACCAAGA CACGACATCT AGCCCTGAAT CTGCAGGAAA AATCCAAGCT GGAGAGTGAG 
CTAGCCAACT TTGGGCCTCG CATTAATGAT ATCAAGAGGA TCATTCAGAG CCGAGAGAGG 
GAAATGAAAG ACTTGAAGGA GAAGATGAAC CAGGTAGAGG ATGAGGTGTT TGAAGAGTTT 
TGTCGGGAGA TTGGTGTGCG CAACATCCGG GAGTTTGAGG AAGAAAAGGT GAAACGGCAG 
AATGAAATCG CCAAGAAGCG TTTGGAGTTT GAGAATCAGA AGACTCGCTT GGGCATTCAG 
TTGGATTTTG AAAAGAACCA ACTGAAGGAG GACCAAGATA AAGTACACAT GTGGGAGCAG 
ACAGTGAAAA AAGATGAAAA TGAGATAGAA AAGCTCAAAA AGGAGGAACA AAGACACATG 
AAGATCATAG ATGAGACCAT GGCTCAGCTA CAAGACCTGA AGAATCAGCA TCTGGCCAAG 
AAGTCGGAAG TGAATGACAA GAATCATGAG ATGGAGGAGA TTCGTAAGAA ACTCGGGGGC 
GCCAACAAGG AAATGACCCA TTTACAGAAG GAGGTGACAG CCATTGAGAC CAAGCTTGAA 
CAGAAGCGCA GTGACCGTCA CAACTTGCTA CAGGCCTGTA AGATGCAGGA CATTAAGTTG 
CCACTGTCAA AAGGCACCAT GGATGATATT AGTCAGGAAG AGGGTAGCTC CCAGGGGGAG 
GACTCAGTGA GTGGTTCACA GAGAATTTCC AGTATCTATG CACGAGAGGC CCTCATTGAG 
ATTGACTACG GTGATCTGTG TGAGGATCTG AAGGATGCCC AGGCTGAGGA AGAGATCAAG 
CAAGAGATGA ACACACTGCA GCAGAAGCTG AATGAGCAGC AGAGTGTGCT TCAGCGTATT 
GCCGCCCCCA ACATGAAGGC CATGGAAAAG CTGGAAAGTG TCCGAGACAA GTTCCAGGAG 
ACCTCAGATG AGTTTGAAGC AGCCCGAAAG CGAGCAAAGA AGGCCAAGCA GGCATTCGAA 
CAGATCAAGA AGGAGCGCTT TGACCGCTTC AATGCTTGTT TTGAATCTGT GGCTACCAAC 
ATTGATGAGA TCTATAAGGC CCTGTCCCGC AATAGCAGTG CCCAGGCATT CCTGGGCCCT 
GAGAACCCTG AAGAGCCCTA CTTGGATGGC ATCAACTACA ACTGTGTGGC TCCTGGGAAA 
CGCTTCCGGC CTATGGACAA CTTGTCAGGC GGGGAGAAGA CAGTGGCAGC TCTGGCCCTG 
CTCTTTGCCA TCCACAGCTA CAAGCCAGCC CCCTTCTTCG TCCTGGATGA GATTGATGCT 
GCCTTGGATA ACACCAACAT TGGCAAGGTG GCAAATTACA TCAAGGAGCA GTCGACTTGC 
AACTTCCAGG CCATCGTCAT CTCTCTCAAG GAGGAGTTCT ACACCAAGGC CGAGAGCCTC 
ATTGGAGTCT ATCCTGAGCA AGGGGACTGT GTGATCAGCA AAGTCCTGAC CTTCGACCTC 
ACCAAGTACC CAGATGCCAA CCCCAACCCC AATGAGCAGT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SMC1A ( NM_001281463.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001268392.1 Homo sapiens structural maintenance of chromosomes 1A (SMC1A), transcript variant 2, mRNA.

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CloneID	OHu29161
Clone ID Related Accession (Same CDS sequence)	NM_001281463.1
Accession Version	NM_001281463.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3636bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-09
Organism	Homo sapiens(human)
Product	structural maintenance of chromosomes protein 1A isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC233728.4. This sequence is a reference standard in the RefSeqGene project. Transcript Variant: This variant (2) differs in the 5' UTR and has multiple coding region differences, compared to variant 1. These differences cause translation initiation at a downstream AUG and result in an isoform (2) with a shorter N-terminus, compared to isoform 1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803617.4606.1, SRR1803615.245523.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END##

ATGCTTGAGG TGTCGATCCC CACCCCCCAC CGCTATGTCA GAGGTAAGTC AAATCTCATG 
GATGCCATCA GCTTTGTGCT AGGTGAAAAA ACCAGCAACC TGCGGGTAAA GACCCTGCGG 
GACCTGATCC ATGGAGCTCC TGTGGGCAAG CCAGCTGCCA ACCGGGCCTT TGTCAGCATG 
GTCTACTCTG AGGAGGGTGC TGAGGACCGT ACCTTTGCCC GTGTCATTGT AGGAGGTTCT 
TCTGAGTACA AGATCAACAA CAAAGTGGTC CAACTACATG AGTACAGTGA GGAATTAGAG 
AAGTTGGGCA TTCTCATCAA AGCTCGTAAC TTCCTCGTTT TCCAGGGTGC TGTGGAATCT 
ATTGCCATGA AGAACCCCAA AGAGAGGACA GCTCTATTTG AAGAGATTAG TCGTTCTGGG 
GAGCTGGCGC AGGAGTATGA CAAGCGAAAG AAGGAAATGG TGAAGGCTGA AGAGGACACA 
CAGTTTAATT ACCATCGCAA GAAAAATATT GCGGCTGAAC GCAAGGAAGC AAAGCAGGAG 
AAAGAAGAGG CTGACCGGTA CCAGCGCCTG AAGGATGAGG TAGTACGGGC TCAGGTACAG 
CTGCAGCTCT TTAAGCTTTA CCATAATGAA GTGGAAATTG AGAAGCTCAA CAAGGAACTG 
GCCTCAAAGA ACAAGGAGAT CGAGAAGGAC AAGAAGCGTA TGGACAAGGT GGAGGATGAA 
CTGAAGGAGA AGAAGAAGGA GCTGGGCAAA ATGATGCGGG AGCAGCAGCA GATTGAGAAG 
GAGATCAAGG AGAAGGACTC AGAATTGAAC CAGAAGCGGC CTCAGTACAT CAAAGCCAAG 
GAGAACACCT CCCACAAAAT CAAGAAGCTG GAAGCAGCCA AGAAGTCTCT GCAGAATGCT 
CAGAAGCACT ACAAGAAGCG TAAAGGTGAC ATGGATGAGC TGGAGAAGGA GATGCTGTCA 
GTGGAGAAGG CTCGGCAGGA GTTTGAAGAA CGGATGGAAG AAGAGAGTCA GAGTCAGGGC 
AGAGATTTGA CGTTGGAGGA GAATCAGGTG AAGAAATACC ACCGGTTGAA AGAAGAAGCC 
AGCAAGAGAG CAGCTACCCT GGCCCAGGAG CTGGAGAAAT TCAATCGAGA CCAGAAAGCT 
GACCAGGACC GTCTGGATCT GGAAGAACGG AAGAAAGTAG AGACAGAGGC CAAGATCAAG 
CAAAAGCTGC GGGAAATTGA AGAGAATCAG AAGCGGATTG AGAAACTGGA GGAATACATC 
ACCACTAGCA AGCAGTCCCT AGAAGAGCAG AAGAAGCTAG AGGGGGAGCT GACAGAGGAG 
GTGGAGATGG CCAAGCGGCG TATTGATGAA ATCAATAAGG AGCTGAACCA GGTGATGGAG 
CAGCTAGGGG ATGCCCGCAT CGACCGCCAG GAGAGCAGCC GCCAGCAGCG AAAGGCAGAG 
ATAATGGAAA GCATCAAGCG CCTTTACCCT GGCTCTGTGT ACGGCCGCCT CATTGACCTA 
TGCCAGCCCA CACAAAAGAA GTATCAGATT GCTGTAACCA AGGTTTTGGG CAAGAACATG 
GATGCCATTA TTGTGGACTC GGAGAAGACA GGCCGGGACT GTATTCAGTA TATCAAGGAG 
CAGCGTGGGG AGCCTGAGAC CTTCTTGCCT CTTGACTACC TGGAGGTGAA GCCTACAGAT 
GAGAAACTCC GGGAGCTGAA GGGGGCCAAG CTAGTGATTG ATGTGATTCG CTATGAGCCA 
CCTCATATCA AAAAGGCCCT GCAGTATGCT TGTGGCAATG CCCTTGTCTG TGACAACGTG 
GAAGATGCCC GCCGCATTGC CTTTGGAGGC CACCAGCGCC ACAAGACAGT GGCACTGGAT 
GGAACCCTAT TCCAGAAGTC AGGAGTGATC TCTGGTGGGG CCAGTGACCT GAAGGCCAAG 
GCACGGCGCT GGGATGAGAA AGCAGTAGAC AAGTTGAAAG AGAAGAAGGA GCGCTTGACA 
GAGGAGCTGA AAGAGCAGAT GAAGGCAAAA CGGAAAGAGG CAGAGCTGCG TCAGGTGCAG 
TCTCAGGCCC ATGGACTGCA GATGCGGCTC AAGTACTCCC AGAGTGACCT AGAACAGACC 
AAGACACGAC ATCTAGCCCT GAATCTGCAG GAAAAATCCA AGCTGGAGAG TGAGCTAGCC 
AACTTTGGGC CTCGCATTAA TGATATCAAG AGGATCATTC AGAGCCGAGA GAGGGAAATG 
AAAGACTTGA AGGAGAAGAT GAACCAGGTA GAGGATGAGG TGTTTGAAGA GTTTTGTCGG 
GAGATTGGTG TGCGCAACAT CCGGGAGTTT GAGGAAGAAA AGGTGAAACG GCAGAATGAA 
ATCGCCAAGA AGCGTTTGGA GTTTGAGAAT CAGAAGACTC GCTTGGGCAT TCAGTTGGAT 
TTTGAAAAGA ACCAACTGAA GGAGGACCAA GATAAAGTAC ACATGTGGGA GCAGACAGTG 
AAAAAAGATG AAAATGAGAT AGAAAAGCTC AAAAAGGAGG AACAAAGACA CATGAAGATC 
ATAGATGAGA CCATGGCTCA GCTACAAGAC CTGAAGAATC AGCATCTGGC CAAGAAGTCG 
GAAGTGAATG ACAAGAATCA TGAGATGGAG GAGATTCGTA AGAAACTCGG GGGCGCCAAC 
AAGGAAATGA CCCATTTACA GAAGGAGGTG ACAGCCATTG AGACCAAGCT TGAACAGAAG 
CGCAGTGACC GTCACAACTT GCTACAGGCC TGTAAGATGC AGGACATTAA GTTGCCACTG 
TCAAAAGGCA CCATGGATGA TATTAGTCAG GAAGAGGGTA GCTCCCAGGG GGAGGACTCA 
GTGAGTGGTT CACAGAGAAT TTCCAGTATC TATGCACGAG AGGCCCTCAT TGAGATTGAC 
TACGGTGATC TGTGTGAGGA TCTGAAGGAT GCCCAGGCTG AGGAAGAGAT CAAGCAAGAG 
ATGAACACAC TGCAGCAGAA GCTGAATGAG CAGCAGAGTG TGCTTCAGCG TATTGCCGCC 
CCCAACATGA AGGCCATGGA AAAGCTGGAA AGTGTCCGAG ACAAGTTCCA GGAGACCTCA 
GATGAGTTTG AAGCAGCCCG AAAGCGAGCA AAGAAGGCCA AGCAGGCATT CGAACAGATC 
AAGAAGGAGC GCTTTGACCG CTTCAATGCT TGTTTTGAAT CTGTGGCTAC CAACATTGAT 
GAGATCTATA AGGCCCTGTC CCGCAATAGC AGTGCCCAGG CATTCCTGGG CCCTGAGAAC 
CCTGAAGAGC CCTACTTGGA TGGCATCAAC TACAACTGTG TGGCTCCTGG GAAACGCTTC 
CGGCCTATGG ACAACTTGTC AGGCGGGGAG AAGACAGTGG CAGCTCTGGC CCTGCTCTTT 
GCCATCCACA GCTACAAGCC AGCCCCCTTC TTCGTCCTGG ATGAGATTGA TGCTGCCTTG 
GATAACACCA ACATTGGCAA GGTGGCAAAT TACATCAAGG AGCAGTCGAC TTGCAACTTC 
CAGGCCATCG TCATCTCTCT CAAGGAGGAG TTCTACACCA AGGCCGAGAG CCTCATTGGA 
GTCTATCCTG AGCAAGGGGA CTGTGTGATC AGCAAAGTCC TGACCTTCGA CCTCACCAAG 
TACCCAGATG CCAACCCCAA CCCCAATGAG CAGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001268392.1
CDS	341..3976
Translation	MLEVSIPTPHRYVRGKSNLMDAISFVLGEKTSNLRVKTLRDLIHGAPVGKPAANRAFVSMVYSEEGAEDRTFARVIVGGSSEYKINNKVVQLHEYSEELEKLGILIKARNFLVFQGAVESIAMKNPKERTALFEEISRSGELAQEYDKRKKEMVKAEEDTQFNYHRKKNIAAERKEAKQEKEEADRYQRLKDEVVRAQVQLQLFKLYHNEVEIEKLNKELASKNKEIEKDKKRMDKVEDELKEKKKELGKMMREQQQIEKEIKEKDSELNQKRPQYIKAKENTSHKIKKLEAAKKSLQNAQKHYKKRKGDMDELEKEMLSVEKARQEFEERMEEESQSQGRDLTLEENQVKKYHRLKEEASKRAATLAQELEKFNRDQKADQDRLDLEERKKVETEAKIKQKLREIEENQKRIEKLEEYITTSKQSLEEQKKLEGELTEEVEMAKRRIDEINKELNQVMEQLGDARIDRQESSRQQRKAEIMESIKRLYPGSVYGRLIDLCQPTQKKYQIAVTKVLGKNMDAIIVDSEKTGRDCIQYIKEQRGEPETFLPLDYLEVKPTDEKLRELKGAKLVIDVIRYEPPHIKKALQYACGNALVCDNVEDARRIAFGGHQRHKTVALDGTLFQKSGVISGGASDLKAKARRWDEKAVDKLKEKKERLTEELKEQMKAKRKEAELRQVQSQAHGLQMRLKYSQSDLEQTKTRHLALNLQEKSKLESELANFGPRINDIKRIIQSREREMKDLKEKMNQVEDEVFEEFCREIGVRNIREFEEEKVKRQNEIAKKRLEFENQKTRLGIQLDFEKNQLKEDQDKVHMWEQTVKKDENEIEKLKKEEQRHMKIIDETMAQLQDLKNQHLAKKSEVNDKNHEMEEIRKKLGGANKEMTHLQKEVTAIETKLEQKRSDRHNLLQACKMQDIKLPLSKGTMDDISQEEGSSQGEDSVSGSQRISSIYAREALIEIDYGDLCEDLKDAQAEEEIKQEMNTLQQKLNEQQSVLQRIAAPNMKAMEKLESVRDKFQETSDEFEAARKRAKKAKQAFEQIKKERFDRFNACFESVATNIDEIYKALSRNSSAQAFLGPENPEEPYLDGINYNCVAPGKRFRPMDNLSGGEKTVAALALLFAIHSYKPAPFFVLDEIDAALDNTNIGKVANYIKEQSTCNFQAIVISLKEEFYTKAESLIGVYPEQGDCVISKVLTFDLTKYPDANPNPNEQ

Target ORF information:

RefSeq Version	NM_001281463.1
Organism	Homo sapiens(human)
Definition	Homo sapiens structural maintenance of chromosomes 1A (SMC1A), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001281463.1

ORF Insert Sequence:

ATGCTTGAGG TGTCGATCCC CACCCCCCAC CGCTATGTCA GAGGTAAGTC AAATCTCATG 
GATGCCATCA GCTTTGTGCT AGGTGAAAAA ACCAGCAACC TGCGGGTAAA GACCCTGCGG 
GACCTGATCC ATGGAGCTCC TGTGGGCAAG CCAGCTGCCA ACCGGGCCTT TGTCAGCATG 
GTCTACTCTG AGGAGGGTGC TGAGGACCGT ACCTTTGCCC GTGTCATTGT AGGAGGTTCT 
TCTGAGTACA AGATCAACAA CAAAGTGGTC CAACTACATG AGTACAGTGA GGAATTAGAG 
AAGTTGGGCA TTCTCATCAA AGCTCGTAAC TTCCTCGTTT TCCAGGGTGC TGTGGAATCT 
ATTGCCATGA AGAACCCCAA AGAGAGGACA GCTCTATTTG AAGAGATTAG TCGTTCTGGG 
GAGCTGGCGC AGGAGTATGA CAAGCGAAAG AAGGAAATGG TGAAGGCTGA AGAGGACACA 
CAGTTTAATT ACCATCGCAA GAAAAATATT GCGGCTGAAC GCAAGGAAGC AAAGCAGGAG 
AAAGAAGAGG CTGACCGGTA CCAGCGCCTG AAGGATGAGG TAGTACGGGC TCAGGTACAG 
CTGCAGCTCT TTAAGCTTTA CCATAATGAA GTGGAAATTG AGAAGCTCAA CAAGGAACTG 
GCCTCAAAGA ACAAGGAGAT CGAGAAGGAC AAGAAGCGTA TGGACAAGGT GGAGGATGAA 
CTGAAGGAGA AGAAGAAGGA GCTGGGCAAA ATGATGCGGG AGCAGCAGCA GATTGAGAAG 
GAGATCAAGG AGAAGGACTC AGAATTGAAC CAGAAGCGGC CTCAGTACAT CAAAGCCAAG 
GAGAACACCT CCCACAAAAT CAAGAAGCTG GAAGCAGCCA AGAAGTCTCT GCAGAATGCT 
CAGAAGCACT ACAAGAAGCG TAAAGGTGAC ATGGATGAGC TGGAGAAGGA GATGCTGTCA 
GTGGAGAAGG CTCGGCAGGA GTTTGAAGAA CGGATGGAAG AAGAGAGTCA GAGTCAGGGC 
AGAGATTTGA CGTTGGAGGA GAATCAGGTG AAGAAATACC ACCGGTTGAA AGAAGAAGCC 
AGCAAGAGAG CAGCTACCCT GGCCCAGGAG CTGGAGAAAT TCAATCGAGA CCAGAAAGCT 
GACCAGGACC GTCTGGATCT GGAAGAACGG AAGAAAGTAG AGACAGAGGC CAAGATCAAG 
CAAAAGCTGC GGGAAATTGA AGAGAATCAG AAGCGGATTG AGAAACTGGA GGAATACATC 
ACCACTAGCA AGCAGTCCCT AGAAGAGCAG AAGAAGCTAG AGGGGGAGCT GACAGAGGAG 
GTGGAGATGG CCAAGCGGCG TATTGATGAA ATCAATAAGG AGCTGAACCA GGTGATGGAG 
CAGCTAGGGG ATGCCCGCAT CGACCGCCAG GAGAGCAGCC GCCAGCAGCG AAAGGCAGAG 
ATAATGGAAA GCATCAAGCG CCTTTACCCT GGCTCTGTGT ACGGCCGCCT CATTGACCTA 
TGCCAGCCCA CACAAAAGAA GTATCAGATT GCTGTAACCA AGGTTTTGGG CAAGAACATG 
GATGCCATTA TTGTGGACTC GGAGAAGACA GGCCGGGACT GTATTCAGTA TATCAAGGAG 
CAGCGTGGGG AGCCTGAGAC CTTCTTGCCT CTTGACTACC TGGAGGTGAA GCCTACAGAT 
GAGAAACTCC GGGAGCTGAA GGGGGCCAAG CTAGTGATTG ATGTGATTCG CTATGAGCCA 
CCTCATATCA AAAAGGCCCT GCAGTATGCT TGTGGCAATG CCCTTGTCTG TGACAACGTG 
GAAGATGCCC GCCGCATTGC CTTTGGAGGC CACCAGCGCC ACAAGACAGT GGCACTGGAT 
GGAACCCTAT TCCAGAAGTC AGGAGTGATC TCTGGTGGGG CCAGTGACCT GAAGGCCAAG 
GCACGGCGCT GGGATGAGAA AGCAGTAGAC AAGTTGAAAG AGAAGAAGGA GCGCTTGACA 
GAGGAGCTGA AAGAGCAGAT GAAGGCAAAA CGGAAAGAGG CAGAGCTGCG TCAGGTGCAG 
TCTCAGGCCC ATGGACTGCA GATGCGGCTC AAGTACTCCC AGAGTGACCT AGAACAGACC 
AAGACACGAC ATCTAGCCCT GAATCTGCAG GAAAAATCCA AGCTGGAGAG TGAGCTAGCC 
AACTTTGGGC CTCGCATTAA TGATATCAAG AGGATCATTC AGAGCCGAGA GAGGGAAATG 
AAAGACTTGA AGGAGAAGAT GAACCAGGTA GAGGATGAGG TGTTTGAAGA GTTTTGTCGG 
GAGATTGGTG TGCGCAACAT CCGGGAGTTT GAGGAAGAAA AGGTGAAACG GCAGAATGAA 
ATCGCCAAGA AGCGTTTGGA GTTTGAGAAT CAGAAGACTC GCTTGGGCAT TCAGTTGGAT 
TTTGAAAAGA ACCAACTGAA GGAGGACCAA GATAAAGTAC ACATGTGGGA GCAGACAGTG 
AAAAAAGATG AAAATGAGAT AGAAAAGCTC AAAAAGGAGG AACAAAGACA CATGAAGATC 
ATAGATGAGA CCATGGCTCA GCTACAAGAC CTGAAGAATC AGCATCTGGC CAAGAAGTCG 
GAAGTGAATG ACAAGAATCA TGAGATGGAG GAGATTCGTA AGAAACTCGG GGGCGCCAAC 
AAGGAAATGA CCCATTTACA GAAGGAGGTG ACAGCCATTG AGACCAAGCT TGAACAGAAG 
CGCAGTGACC GTCACAACTT GCTACAGGCC TGTAAGATGC AGGACATTAA GTTGCCACTG 
TCAAAAGGCA CCATGGATGA TATTAGTCAG GAAGAGGGTA GCTCCCAGGG GGAGGACTCA 
GTGAGTGGTT CACAGAGAAT TTCCAGTATC TATGCACGAG AGGCCCTCAT TGAGATTGAC 
TACGGTGATC TGTGTGAGGA TCTGAAGGAT GCCCAGGCTG AGGAAGAGAT CAAGCAAGAG 
ATGAACACAC TGCAGCAGAA GCTGAATGAG CAGCAGAGTG TGCTTCAGCG TATTGCCGCC 
CCCAACATGA AGGCCATGGA AAAGCTGGAA AGTGTCCGAG ACAAGTTCCA GGAGACCTCA 
GATGAGTTTG AAGCAGCCCG AAAGCGAGCA AAGAAGGCCA AGCAGGCATT CGAACAGATC 
AAGAAGGAGC GCTTTGACCG CTTCAATGCT TGTTTTGAAT CTGTGGCTAC CAACATTGAT 
GAGATCTATA AGGCCCTGTC CCGCAATAGC AGTGCCCAGG CATTCCTGGG CCCTGAGAAC 
CCTGAAGAGC CCTACTTGGA TGGCATCAAC TACAACTGTG TGGCTCCTGG GAAACGCTTC 
CGGCCTATGG ACAACTTGTC AGGCGGGGAG AAGACAGTGG CAGCTCTGGC CCTGCTCTTT 
GCCATCCACA GCTACAAGCC AGCCCCCTTC TTCGTCCTGG ATGAGATTGA TGCTGCCTTG 
GATAACACCA ACATTGGCAA GGTGGCAAAT TACATCAAGG AGCAGTCGAC TTGCAACTTC 
CAGGCCATCG TCATCTCTCT CAAGGAGGAG TTCTACACCA AGGCCGAGAG CCTCATTGGA 
GTCTATCCTG AGCAAGGGGA CTGTGTGATC AGCAAAGTCC TGACCTTCGA CCTCACCAAG 
TACCCAGATG CCAACCCCAA CCCCAATGAG CAGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

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SMC1A cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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見積依頼

Eメール

電話

FAX

オンラインフォーム

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