MIA cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	MIA
Entrez Gene ID	8190
Full Name	melanoma inhibitory activity
Synonyms	CD-RAP
General protein information	Preferred Names melanoma inhibitory activity Names melanoma-derived growth regulatory protein
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 19 Map Location: 19q13.2
Disorder MIM:	601340

mRNA and Protein(s)

mRNA	Protein	Name
NM_001202553.1	NP_001189482.1	melanoma-derived growth regulatory protein precursor
NM_006533.3	NP_006524.1	melanoma-derived growth regulatory protein precursor
NM_006533.4	NP_006524.1	melanoma-derived growth regulatory protein precursor
NM_001202553.2	NP_001189482.1	melanoma-derived growth regulatory protein precursor

Pathways from BioSystems

Homologies

	MIA	XP_001098600.1
Rattus norvegicus (Norway rat)	Mia	NP_110479.1
Homo sapiens (human)	MIA	NP_001189482.1
Canis lupus familiaris (dog)	MIA	XP_541610.3
Bos taurus (cattle)	MIA	NP_776361.1
Mus musculus (house mouse)	Mia	NP_062267.2
Xenopus tropicalis (tropical clawed frog)	mia	NP_001135716.1
Pan troglodytes (chimpanzee)	MIA	XP_001146858.1
Danio rerio (zebrafish)	zgc:194158	NP_001122226.1

Gene Ontology
Bibliography

Related articles in PubMed

Comparison of the Serum Tumor Markers S100 and Melanoma-inhibitory Activity (MIA) in the Monitoring of Patients with Metastatic Melanoma Receiving Vaccination Immunotherapy with Dendritic Cells.
Uslu U, Schliep S, Schliep K, Erdmann M, Koch HU, Parsch H, Rosenheinrich S, Anzengruber D, Bosserhoff AK, Schuler G, Schuler-Thurner B
Anticancer research37(9)5033-5037(2017 09)

Human melanoma inhibitory protein binds to the FN12-14 Hep II domain of fibronectin.
Yip KT, Zhong X, Seibel N, Arnolds O, Sch?pel M, Stoll R
Biointerphases12(2)02D415(2017 May)

Chromosome 19q13 disruption alters expressions of CYP2A7, MIA and MIA-RAB4B lncRNA and contributes to FAP-like phenotype in APC mutation-negative familial colorectal cancer patients.
Thean LF, Wong YH, Lo M, Loi C, Chew MH, Tang CL, Cheah PY
PloS one12(3)e0173772(2017)

Storkhead box 2 and melanoma inhibitory activity promote oral squamous cell carcinoma progression.
Sasahira T, Nishiguchi Y, Fujiwara R, Kurihara M, Kirita T, Bosserhoff AK, Kuniyasu H
Oncotarget7(18)26751-64(2016 May)

A comprehensive expression analysis of the MIA gene family in malignancies: MIA gene family members are novel, useful markers of esophageal, lung, and cervical squamous cell carcinoma.
Sasahira T, Kirita T, Nishiguchi Y, Kurihara M, Nakashima C, Bosserhoff AK, Kuniyasu H
Oncotarget7(21)31137-52(2016 May)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

MIA had a slightly superior sensitivity to detect progressive disease compared to S100 and seems to be more useful in monitoring of patients with metastatic melanoma receiving immunotherapy
Title: Comparison of the Serum Tumor Markers S100 and Melanoma-inhibitory Activity (MIA) in the Monitoring of Patients with Metastatic Melanoma Receiving Vaccination Immunotherapy with Dendritic Cells.

real-time RT-PCR assays showed that expressions of MIA and MIA-RAB4B located 35 kb upstream of the deletion, were up-regulated in the polyps compared to the matched mucosa of the proband. MIA-RAB4B, the read-through long non-coding RNA (lncRNA), RAB4B, PIM2 and TAOK1 share common binding site of a microRNA, miR-24, in their 3'UTRs
Title: Chromosome 19q13 disruption alters expressions of CYP2A7, MIA and MIA-RAB4B lncRNA and contributes to FAP-like phenotype in APC mutation-negative familial colorectal cancer patients.

Our results suggest that MIA-STOX2 signaling may be a useful diagnostic and therapeutic target in oral squamous cell carcinoma
Title: Storkhead box 2 and melanoma inhibitory activity promote oral squamous cell carcinoma progression.

The frequency of MIA gene family expression was higher among squamous cell carcinomas than among other tumor types subjected to screening. MIA gene family staining was observed frequently in esophageal and lung cancers associated with nodal and/or distant metastasis. In cervical cancers, MIA and TANGO immunostaining also correlated with tumor progression and metastasis.
Title: A comprehensive expression analysis of the MIA gene family in malignancies: MIA gene family members are novel, useful markers of esophageal, lung, and cervical squamous cell carcinoma.

data provide evidence for a critical role of SOX10 in melanoma cell invasion through the regulation of MIA and highlight its role as a therapeutic target in melanoma
Title: SOX10 promotes melanoma cell invasion by regulating melanoma inhibitory activity.

The following MIA gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the MIA cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu23931	NM_006533.4 Latest version!	Homo sapiens MIA SH3 domain containing (MIA), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu23931	NM_001202553.2 Latest version!	Homo sapiens MIA SH3 domain containing (MIA), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
View Old Accession Versions >>
OHu23931	NM_006533.3	Homo sapiens melanoma inhibitory activity (MIA), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu23931	NM_001202553.1	Homo sapiens MIA SH3 domain containing (MIA), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

MIA ( NM_001202553.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001189482.1 Homo sapiens MIA SH3 domain containing (MIA), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu23931
Clone ID Related Accession (Same CDS sequence)	NM_001202553.1 , NM_006533.3 , NM_006533.4 , NM_001202553.2
Accession Version	NM_001202553.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 396bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-06-24
Organism	Homo sapiens(human)
Product	melanoma-derived growth regulatory protein precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BQ681978.1, BM715936.1, BM856478.1 and DV462488.1. Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Both variants 1 and 2 encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BQ681978.1, BM674250.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA1968832 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCCCGGT CCCTGGTGTG CCTTGGTGTC ATCATCTTGC TGTCTGCCTT CTCCGGACCT 
GGTGTCAGGG GTGGTCCTAT GCCCAAGCTG GCTGACCGGA AGCTGTGTGC GGACCAGGAG 
TGCAGCCACC CTATCTCCAT GGCTGTGGCC CTTCAGGACT ACATGGCCCC CGACTGCCGA 
TTCCTGACCA TTCACCGGGG CCAAGTGGTG TATGTCTTCT CCAAGCTGAA GGGCCGTGGG 
CGGCTCTTCT GGGGAGGCAG CGTTCAGGGA GATTACTATG GAGATCTGGC TGCTCGCCTG 
GGCTATTTCC CCAGTAGCAT TGTCCGAGAG GACCAGACCC TGAAACCTGG CAAAGTCGAT 
GTGAAGACAG ACAAATGGGA TTTCTACTGC CAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001189482.1
CDS	42..437
Translation	MARSLVCLGVIILLSAFSGPGVRGGPMPKLADRKLCADQECSHPISMAVALQDYMAPDCRFLTIHRGQVVYVFSKLKGRGRLFWGGSVQGDYYGDLAARLGYFPSSIVREDQTLKPGKVDVKTDKWDFYCQ

Target ORF information:

RefSeq Version	NM_001202553.1
Organism	Homo sapiens(human)
Definition	Homo sapiens MIA SH3 domain containing (MIA), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001202553.1

ORF Insert Sequence:

ATGGCCCGGT CCCTGGTGTG CCTTGGTGTC ATCATCTTGC TGTCTGCCTT CTCCGGACCT 
GGTGTCAGGG GTGGTCCTAT GCCCAAGCTG GCTGACCGGA AGCTGTGTGC GGACCAGGAG 
TGCAGCCACC CTATCTCCAT GGCTGTGGCC CTTCAGGACT ACATGGCCCC CGACTGCCGA 
TTCCTGACCA TTCACCGGGG CCAAGTGGTG TATGTCTTCT CCAAGCTGAA GGGCCGTGGG 
CGGCTCTTCT GGGGAGGCAG CGTTCAGGGA GATTACTATG GAGATCTGGC TGCTCGCCTG 
GGCTATTTCC CCAGTAGCAT TGTCCGAGAG GACCAGACCC TGAAACCTGG CAAAGTCGAT 
GTGAAGACAG ACAAATGGGA TTTCTACTGC CAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MIA ( NM_006533.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_006524.1 Homo sapiens melanoma inhibitory activity (MIA), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu23931
Clone ID Related Accession (Same CDS sequence)	NM_001202553.1 , NM_006533.3 , NM_006533.4 , NM_001202553.2
Accession Version	NM_006533.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 396bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-09-24
Organism	Homo sapiens(human)
Product	melanoma-derived growth regulatory protein precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BX280685.1, BC005910.1, BM856478.1 and DV462488.1. On Feb 4, 2011 this sequence version replaced NM_006533.2. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Both variants 1 and 2 encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BM791767.1, DR005753.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1966682, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCCCGGT CCCTGGTGTG CCTTGGTGTC ATCATCTTGC TGTCTGCCTT CTCCGGACCT 
GGTGTCAGGG GTGGTCCTAT GCCCAAGCTG GCTGACCGGA AGCTGTGTGC GGACCAGGAG 
TGCAGCCACC CTATCTCCAT GGCTGTGGCC CTTCAGGACT ACATGGCCCC CGACTGCCGA 
TTCCTGACCA TTCACCGGGG CCAAGTGGTG TATGTCTTCT CCAAGCTGAA GGGCCGTGGG 
CGGCTCTTCT GGGGAGGCAG CGTTCAGGGA GATTACTATG GAGATCTGGC TGCTCGCCTG 
GGCTATTTCC CCAGTAGCAT TGTCCGAGAG GACCAGACCC TGAAACCTGG CAAAGTCGAT 
GTGAAGACAG ACAAATGGGA TTTCTACTGC CAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_006524.1
CDS	167..562
Translation	MARSLVCLGVIILLSAFSGPGVRGGPMPKLADRKLCADQECSHPISMAVALQDYMAPDCRFLTIHRGQVVYVFSKLKGRGRLFWGGSVQGDYYGDLAARLGYFPSSIVREDQTLKPGKVDVKTDKWDFYCQ

Target ORF information:

RefSeq Version	NM_006533.3
Organism	Homo sapiens(human)
Definition	Homo sapiens melanoma inhibitory activity (MIA), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_006533.3

ORF Insert Sequence:

ATGGCCCGGT CCCTGGTGTG CCTTGGTGTC ATCATCTTGC TGTCTGCCTT CTCCGGACCT 
GGTGTCAGGG GTGGTCCTAT GCCCAAGCTG GCTGACCGGA AGCTGTGTGC GGACCAGGAG 
TGCAGCCACC CTATCTCCAT GGCTGTGGCC CTTCAGGACT ACATGGCCCC CGACTGCCGA 
TTCCTGACCA TTCACCGGGG CCAAGTGGTG TATGTCTTCT CCAAGCTGAA GGGCCGTGGG 
CGGCTCTTCT GGGGAGGCAG CGTTCAGGGA GATTACTATG GAGATCTGGC TGCTCGCCTG 
GGCTATTTCC CCAGTAGCAT TGTCCGAGAG GACCAGACCC TGAAACCTGG CAAAGTCGAT 
GTGAAGACAG ACAAATGGGA TTTCTACTGC CAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MIA ( NM_006533.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_006524.1 Homo sapiens MIA SH3 domain containing (MIA), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu23931
Clone ID Related Accession (Same CDS sequence)	NM_001202553.1 , NM_006533.3 , NM_006533.4 , NM_001202553.2
Accession Version	NM_006533.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 396bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-27
Organism	Homo sapiens(human)
Product	melanoma-derived growth regulatory protein precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BC005910.1 and BM856478.1. On Nov 23, 2018 this sequence version replaced NM_006533.3. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Both variants 1 and 2 encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC005910.1, BM856478.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1966682, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000263369.4/ ENSP00000263369.2 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGCCCGGT CCCTGGTGTG CCTTGGTGTC ATCATCTTGC TGTCTGCCTT CTCCGGACCT 
GGTGTCAGGG GTGGTCCTAT GCCCAAGCTG GCTGACCGGA AGCTGTGTGC GGACCAGGAG 
TGCAGCCACC CTATCTCCAT GGCTGTGGCC CTTCAGGACT ACATGGCCCC CGACTGCCGA 
TTCCTGACCA TTCACCGGGG CCAAGTGGTG TATGTCTTCT CCAAGCTGAA GGGCCGTGGG 
CGGCTCTTCT GGGGAGGCAG CGTTCAGGGA GATTACTATG GAGATCTGGC TGCTCGCCTG 
GGCTATTTCC CCAGTAGCAT TGTCCGAGAG GACCAGACCC TGAAACCTGG CAAAGTCGAT 
GTGAAGACAG ACAAATGGGA TTTCTACTGC CAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_006524.1
CDS	23..418
Translation	MARSLVCLGVIILLSAFSGPGVRGGPMPKLADRKLCADQECSHPISMAVALQDYMAPDCRFLTIHRGQVVYVFSKLKGRGRLFWGGSVQGDYYGDLAARLGYFPSSIVREDQTLKPGKVDVKTDKWDFYCQ

Target ORF information:

RefSeq Version	NM_006533.4
Organism	Homo sapiens(human)
Definition	Homo sapiens MIA SH3 domain containing (MIA), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_006533.4

ORF Insert Sequence:

ATGGCCCGGT CCCTGGTGTG CCTTGGTGTC ATCATCTTGC TGTCTGCCTT CTCCGGACCT 
GGTGTCAGGG GTGGTCCTAT GCCCAAGCTG GCTGACCGGA AGCTGTGTGC GGACCAGGAG 
TGCAGCCACC CTATCTCCAT GGCTGTGGCC CTTCAGGACT ACATGGCCCC CGACTGCCGA 
TTCCTGACCA TTCACCGGGG CCAAGTGGTG TATGTCTTCT CCAAGCTGAA GGGCCGTGGG 
CGGCTCTTCT GGGGAGGCAG CGTTCAGGGA GATTACTATG GAGATCTGGC TGCTCGCCTG 
GGCTATTTCC CCAGTAGCAT TGTCCGAGAG GACCAGACCC TGAAACCTGG CAAAGTCGAT 
GTGAAGACAG ACAAATGGGA TTTCTACTGC CAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MIA ( NM_001202553.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001189482.1 Homo sapiens MIA SH3 domain containing (MIA), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu23931
Clone ID Related Accession (Same CDS sequence)	NM_001202553.1 , NM_006533.3 , NM_006533.4 , NM_001202553.2
Accession Version	NM_001202553.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 396bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-27
Organism	Homo sapiens(human)
Product	melanoma-derived growth regulatory protein precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC020945.6, BQ681978.1, BM715936.1 and BM856478.1. On May 31, 2019 this sequence version replaced NM_001202553.1. Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Both variants 1 and 2 encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BU157778.1, BQ681978.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA1968832 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCCCGGT CCCTGGTGTG CCTTGGTGTC ATCATCTTGC TGTCTGCCTT CTCCGGACCT 
GGTGTCAGGG GTGGTCCTAT GCCCAAGCTG GCTGACCGGA AGCTGTGTGC GGACCAGGAG 
TGCAGCCACC CTATCTCCAT GGCTGTGGCC CTTCAGGACT ACATGGCCCC CGACTGCCGA 
TTCCTGACCA TTCACCGGGG CCAAGTGGTG TATGTCTTCT CCAAGCTGAA GGGCCGTGGG 
CGGCTCTTCT GGGGAGGCAG CGTTCAGGGA GATTACTATG GAGATCTGGC TGCTCGCCTG 
GGCTATTTCC CCAGTAGCAT TGTCCGAGAG GACCAGACCC TGAAACCTGG CAAAGTCGAT 
GTGAAGACAG ACAAATGGGA TTTCTACTGC CAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001189482.1
CDS	59..454
Translation	MARSLVCLGVIILLSAFSGPGVRGGPMPKLADRKLCADQECSHPISMAVALQDYMAPDCRFLTIHRGQVVYVFSKLKGRGRLFWGGSVQGDYYGDLAARLGYFPSSIVREDQTLKPGKVDVKTDKWDFYCQ

Target ORF information:

RefSeq Version	NM_001202553.2
Organism	Homo sapiens(human)
Definition	Homo sapiens MIA SH3 domain containing (MIA), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001202553.2

ORF Insert Sequence:

ATGGCCCGGT CCCTGGTGTG CCTTGGTGTC ATCATCTTGC TGTCTGCCTT CTCCGGACCT 
GGTGTCAGGG GTGGTCCTAT GCCCAAGCTG GCTGACCGGA AGCTGTGTGC GGACCAGGAG 
TGCAGCCACC CTATCTCCAT GGCTGTGGCC CTTCAGGACT ACATGGCCCC CGACTGCCGA 
TTCCTGACCA TTCACCGGGG CCAAGTGGTG TATGTCTTCT CCAAGCTGAA GGGCCGTGGG 
CGGCTCTTCT GGGGAGGCAG CGTTCAGGGA GATTACTATG GAGATCTGGC TGCTCGCCTG 
GGCTATTTCC CCAGTAGCAT TGTCCGAGAG GACCAGACCC TGAAACCTGG CAAAGTCGAT 
GTGAAGACAG ACAAATGGGA TTTCTACTGC CAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Comparison of the Serum Tumor Markers S100 and Melanoma-inhibitory Activity (MIA) in the Monitoring of Patients with Metastatic Melanoma Receiving Vaccination Immunotherapy with Dendritic Cells.
Anticancer research37(9)5033-5037(2017 09)
Uslu U,Schliep S,Schliep K,Erdmann M,Koch HU,Parsch H,Rosenheinrich S,Anzengruber D,Bosserhoff AK,Schuler G,Schuler-Thurner B

Human melanoma inhibitory protein binds to the FN12-14 Hep II domain of fibronectin.
Biointerphases12(2)02D415(2017 May)
Yip KT,Zhong X,Seibel N,Arnolds O,Sch?pel M,Stoll R

Chromosome 19q13 disruption alters expressions of CYP2A7, MIA and MIA-RAB4B lncRNA and contributes to FAP-like phenotype in APC mutation-negative familial colorectal cancer patients.
PloS one12(3)e0173772(2017)
Thean LF,Wong YH,Lo M,Loi C,Chew MH,Tang CL,Cheah PY

Storkhead box 2 and melanoma inhibitory activity promote oral squamous cell carcinoma progression.
Oncotarget7(18)26751-64(2016 May)
Sasahira T,Nishiguchi Y,Fujiwara R,Kurihara M,Kirita T,Bosserhoff AK,Kuniyasu H

A comprehensive expression analysis of the MIA gene family in malignancies: MIA gene family members are novel, useful markers of esophageal, lung, and cervical squamous cell carcinoma.
Oncotarget7(21)31137-52(2016 May)
Sasahira T,Kirita T,Nishiguchi Y,Kurihara M,Nakashima C,Bosserhoff AK,Kuniyasu H

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MIA cDNA ORF clone, Homo sapiens(human)

Gene

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gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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