FAHD1 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	FAHD1
Entrez Gene ID	81889
Full Name	fumarylacetoacetate hydrolase domain containing 1
Synonyms	C16orf36,YISKL
General protein information	Preferred Names fumarylacetoacetate hydrolase domain containing 1 Names acylpyruvase FAHD1, mitochondrial FAH domain-containing protein 1 OAA decarboxylase YISK like/RJD15 acylpyruvate hydrolase fumarylacetoacetate hydrolase domain-containing protein 1 oxaloacetate decarboxylase yisK-like protein
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 16 Map Location: 16p13.3
Disorder MIM:	616320

mRNA and Protein(s)

mRNA	Protein	Name
NM_031208.3	NP_112485.1	acylpyruvase FAHD1, mitochondrial isoform 2
NM_001018104.2	NP_001018114.1	acylpyruvase FAHD1, mitochondrial isoform 1
NM_001142398.1	NP_001135870.1	acylpyruvase FAHD1, mitochondrial isoform 3

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	FAHD1	XP_001145622.1
Danio rerio (zebrafish)	fahd1	NP_001018564.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP001942	XP_321120.4
Kluyveromyces lactis	KLLA0D08052g	XP_453422.1
Schizosaccharomyces pombe (fission yeast)	SPBC21C3.09c	NP_596589.1
Homo sapiens (human)	FAHD1	NP_112485.1
Bos taurus (cattle)	FAHD1	NP_001068868.1
Caenorhabditis elegans (roundworm)	ZK688.3	NP_498715.1
Neurospora crassa	NCU03283	XP_964209.1
Rattus norvegicus (Norway rat)	Fahd1	NP_001020162.1
Saccharomyces cerevisiae (baker's yeast)	FMP41	NP_014231.1
Oryza sativa (rice)	Os03g0829000	NP_001051779.1
	FAHD1	XP_001118644.2
Mus musculus (house mouse)	Fahd1	NP_075969.1
Gallus gallus (chicken)	FAHD1	NP_001264681.1
Drosophila melanogaster (fruit fly)	CG5793	NP_650944.3
Magnaporthe oryzae (rice blast fungus)	MGG_17430	XP_003718500.1
Arabidopsis thaliana (thale cress)	AT3G16700	NP_188292.1
Arabidopsis thaliana (thale cress)	AT4G15940	NP_193329.1
Xenopus tropicalis (tropical clawed frog)	fahd1	XP_004918119.1
Canis lupus familiaris (dog)	FAHD1	XP_547188.1

Gene Ontology
Bibliography

Related articles in PubMed

Depletion of oxaloacetate decarboxylase FAHD1 inhibits mitochondrial electron transport and induces cellular senescence in human endothelial cells.
Petit M, Koziel R, Etemad S, Pircher H, Jansen-D?rr P
Experimental gerontology927-12(2017 06)

Identification of FAH domain-containing protein 1 (FAHD1) as oxaloacetate decarboxylase.
Pircher H, von Grafenstein S, Diener T, Metzger C, Albertini E, Taferner A, Unterluggauer H, Kramer C, Liedl KR, Jansen-D?rr P
The Journal of biological chemistry290(11)6755-62(2015 Mar)

FAH domain containing protein 1 (FAHD-1) is required for mitochondrial function and locomotion activity in C. elegans.
Taferner A, Pircher H, Koziel R, von Grafenstein S, Baraldo G, Palikaras K, Liedl KR, Tavernarakis N, Jansen-D?rr P
PloS one10(8)e0134161(2015)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The results indicate that FAHD1 is required for mitochondrial function in human cells and provide additional support to the growing evidence that mitochondrial dysfunction can induce cellular senescence by metabolic alterations independent of the DNA damage response pathway.
Title: Depletion of oxaloacetate decarboxylase FAHD1 inhibits mitochondrial electron transport and induces cellular senescence in human endothelial cells.

Based on molecular modeling and subsequent biochemical investigations, the study identified FAHD1 as a eukaryotic oxaloacetate decarboxylase enzyme.
Title: Identification of FAH domain-containing protein 1 (FAHD1) as oxaloacetate decarboxylase.

we recently identified human FAH domain containing protein-1 (FAHD1) as the first eukaryotic oxaloacetate decarboxylase..these data establish a role of fahd-1 to maintain mitochondrial function and consequently physical activity
Title: FAH domain containing protein 1 (FAHD-1) is required for mitochondrial function and locomotion activity in C. elegans.

identified mammalian FAHD1 as a novel mitochondrial enzyme with acylpyruvate hydrolase activity.
Title: Identification of human fumarylacetoacetate hydrolase domain-containing protein 1 (FAHD1) as a novel mitochondrial acylpyruvase.

Observational study of gene-disease association. (HuGE Navigator)
Title: Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.

The following FAHD1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the FAHD1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu00038	NM_001018104.2 Latest version!	Homo sapiens fumarylacetoacetate hydrolase domain containing 1 (FAHD1), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu09214	NM_001142398.1 Latest version!	Homo sapiens fumarylacetoacetate hydrolase domain containing 1 (FAHD1), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$134.50-$188.30 $269.00
OHu32048	NM_031208.3 Latest version!	Homo sapiens fumarylacetoacetate hydrolase domain containing 1 (FAHD1), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$188.30 $269.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

FAHD1 ( NM_001018104.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001018114.1 Homo sapiens fumarylacetoacetate hydrolase domain containing 1 (FAHD1), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu00038
Clone ID Related Accession (Same CDS sequence)	NM_001018104.2
Accession Version	NM_001018104.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 747bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-06-10
Organism	Homo sapiens(human)
Product	acylpyruvase FAHD1, mitochondrial isoform 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL136720.1, AC012180.6, AL031722.20 and BC063017.1. On Dec 2, 2008 this sequence version replaced NM_001018104.1. Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803613.51677.1, SRR1803614.210543.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: reported by MitoCarta RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGGAATCA TGGCAGCATC CAGGCCATTG TCCCGCTTCT GGGAGTGGGG AAAGAACATC 
GTCTGCGTGG GGAGGAACTA CGCGGACCAC GTCAGGGAGA TGCGCAGCGC GGTGTTGAGC 
GAGCCCGTGC TGTTCCTGAA GCCGTCCACG GCCTACGCGC CCGAGGGCTC GCCCATCCTC 
ATGCCCGCGT ACACTCGCAA CCTGCACCAC GAGCTGGAGC TGGGCGTGGT GATGGGCAAG 
CGCTGCCGCG CAGTCCCCGA GGCTGCGGCC ATGGACTACG TGGGCGGCTA TGCCCTGTGC 
CTGGATATGA CCGCCCGGGA CGTGCAGGAC GAGTGCAAGA AGAAGGGGCT GCCCTGGACT 
CTGGCGAAGA GCTTCACGGC GTCCTGCCCG GTCAGCGCGT TCGTGCCCAA GGAGAAGATC 
CCTGACCCTC ACAAGCTGAA GCTCTGGCTC AAGGTCAACG GCGAACTCAG ACAGGAGGGT 
GAGACATCCT CCATGATTTT TTCCATCCCC TACATCATCA GCTATGTTTC TAAGATCATA 
ACCTTGGAAG AAGGAGATAT TATCTTGACT GGGACGCCAA AGGGAGTTGG ACCGGTTAAA 
GAAAACGATG AGATCGAGGC TGGCATACAC GGGCTGAGAC AGGGTCTCAC TCTGTCGCCC 
AAGCTGGAGT GCAGCAGTGC TATCACAGCT CACTGCAGCC TCGAACTCCC GGGGTCAAGC 
AATCCTCCCT CAGCTTCCCG TTTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001018114.1
CDS	7..753
Translation	MGIMAASRPLSRFWEWGKNIVCVGRNYADHVREMRSAVLSEPVLFLKPSTAYAPEGSPILMPAYTRNLHHELELGVVMGKRCRAVPEAAAMDYVGGYALCLDMTARDVQDECKKKGLPWTLAKSFTASCPVSAFVPKEKIPDPHKLKLWLKVNGELRQEGETSSMIFSIPYIISYVSKIITLEEGDIILTGTPKGVGPVKENDEIEAGIHGLRQGLTLSPKLECSSAITAHCSLELPGSSNPPSASRF

Target ORF information:

RefSeq Version	NM_001018104.2
Organism	Homo sapiens(human)
Definition	Homo sapiens fumarylacetoacetate hydrolase domain containing 1 (FAHD1), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001018104.2

ORF Insert Sequence:

ATGGGAATCA TGGCAGCATC CAGGCCATTG TCCCGCTTCT GGGAGTGGGG AAAGAACATC 
GTCTGCGTGG GGAGGAACTA CGCGGACCAC GTCAGGGAGA TGCGCAGCGC GGTGTTGAGC 
GAGCCCGTGC TGTTCCTGAA GCCGTCCACG GCCTACGCGC CCGAGGGCTC GCCCATCCTC 
ATGCCCGCGT ACACTCGCAA CCTGCACCAC GAGCTGGAGC TGGGCGTGGT GATGGGCAAG 
CGCTGCCGCG CAGTCCCCGA GGCTGCGGCC ATGGACTACG TGGGCGGCTA TGCCCTGTGC 
CTGGATATGA CCGCCCGGGA CGTGCAGGAC GAGTGCAAGA AGAAGGGGCT GCCCTGGACT 
CTGGCGAAGA GCTTCACGGC GTCCTGCCCG GTCAGCGCGT TCGTGCCCAA GGAGAAGATC 
CCTGACCCTC ACAAGCTGAA GCTCTGGCTC AAGGTCAACG GCGAACTCAG ACAGGAGGGT 
GAGACATCCT CCATGATTTT TTCCATCCCC TACATCATCA GCTATGTTTC TAAGATCATA 
ACCTTGGAAG AAGGAGATAT TATCTTGACT GGGACGCCAA AGGGAGTTGG ACCGGTTAAA 
GAAAACGATG AGATCGAGGC TGGCATACAC GGGCTGAGAC AGGGTCTCAC TCTGTCGCCC 
AAGCTGGAGT GCAGCAGTGC TATCACAGCT CACTGCAGCC TCGAACTCCC GGGGTCAAGC 
AATCCTCCCT CAGCTTCCCG TTTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

FAHD1 ( NM_001142398.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001135870.1 Homo sapiens fumarylacetoacetate hydrolase domain containing 1 (FAHD1), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu09214
Clone ID Related Accession (Same CDS sequence)	NM_001142398.1
Accession Version	NM_001142398.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 681bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-06-10
Organism	Homo sapiens(human)
Product	acylpyruvase FAHD1, mitochondrial isoform 3
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BC063017.1. Transcript Variant: This variant (3) lacks an alternate exon compared to variant 1. The resulting isoform (3) has a shorter and distinct C-terminus compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC063017.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA2144835 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: reported by MitoCarta ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGGAATCA TGGCAGCATC CAGGCCATTG TCCCGCTTCT GGGAGTGGGG AAAGAACATC 
GTCTGCGTGG GGAGGAACTA CGCGGACCAC GTCAGGGAGA TGCGCAGCGC GGTGTTGAGC 
GAGCCCGTGC TGTTCCTGAA GCCGTCCACG GCCTACGCGC CCGAGGGCTC GCCCATCCTC 
ATGCCCGCGT ACACTCGCAA CCTGCACCAC GAGCTGGAGC TGGGCGTGGT GATGGGCAAG 
CGCTGCCGCG CAGTCCCCGA GGCTGCGGCC ATGGACTACG TGGGCGGCTA TGCCCTGTGC 
CTGGATATGA CCGCCCGGGA CGTGCAGGAC GAGTGCAAGA AGAAGGGGCT GCCCTGGACT 
CTGGCGAAGA GCTTCACGGC GTCCTGCCCG GTCAGCGCGT TCGTGCCCAA GGAGAAGATC 
CCTGACCCTC ACAAGCTGAA GCTCTGGCTC AAGGTCAACG GCGAACTCAG ACAGGAGGGT 
GAGACATCCT CCATGATTTT TTCCATCCCC TACATCATCA GCTATGTTTC TAAGATCATA 
ACCTTGGAAG AAGGAGATAT TATCTTGACT GGGACGCCAA AGGGAGTTGG ACCGGTTAAA 
GAAAACGATG AGATCGAGGC TGGCATACAC GGGCTGCCCA AAGTCTCCTC AGCAACACTT 
CCTGTGAGAC TACAGGAATG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001135870.1
CDS	7..687
Translation	MGIMAASRPLSRFWEWGKNIVCVGRNYADHVREMRSAVLSEPVLFLKPSTAYAPEGSPILMPAYTRNLHHELELGVVMGKRCRAVPEAAAMDYVGGYALCLDMTARDVQDECKKKGLPWTLAKSFTASCPVSAFVPKEKIPDPHKLKLWLKVNGELRQEGETSSMIFSIPYIISYVSKIITLEEGDIILTGTPKGVGPVKENDEIEAGIHGLPKVSSATLPVRLQE

Target ORF information:

RefSeq Version	NM_001142398.1
Organism	Homo sapiens(human)
Definition	Homo sapiens fumarylacetoacetate hydrolase domain containing 1 (FAHD1), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001142398.1

ORF Insert Sequence:

ATGGGAATCA TGGCAGCATC CAGGCCATTG TCCCGCTTCT GGGAGTGGGG AAAGAACATC 
GTCTGCGTGG GGAGGAACTA CGCGGACCAC GTCAGGGAGA TGCGCAGCGC GGTGTTGAGC 
GAGCCCGTGC TGTTCCTGAA GCCGTCCACG GCCTACGCGC CCGAGGGCTC GCCCATCCTC 
ATGCCCGCGT ACACTCGCAA CCTGCACCAC GAGCTGGAGC TGGGCGTGGT GATGGGCAAG 
CGCTGCCGCG CAGTCCCCGA GGCTGCGGCC ATGGACTACG TGGGCGGCTA TGCCCTGTGC 
CTGGATATGA CCGCCCGGGA CGTGCAGGAC GAGTGCAAGA AGAAGGGGCT GCCCTGGACT 
CTGGCGAAGA GCTTCACGGC GTCCTGCCCG GTCAGCGCGT TCGTGCCCAA GGAGAAGATC 
CCTGACCCTC ACAAGCTGAA GCTCTGGCTC AAGGTCAACG GCGAACTCAG ACAGGAGGGT 
GAGACATCCT CCATGATTTT TTCCATCCCC TACATCATCA GCTATGTTTC TAAGATCATA 
ACCTTGGAAG AAGGAGATAT TATCTTGACT GGGACGCCAA AGGGAGTTGG ACCGGTTAAA 
GAAAACGATG AGATCGAGGC TGGCATACAC GGGCTGCCCA AAGTCTCCTC AGCAACACTT 
CCTGTGAGAC TACAGGAATG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

FAHD1 ( NM_031208.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_112485.1 Homo sapiens fumarylacetoacetate hydrolase domain containing 1 (FAHD1), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu32048
Clone ID Related Accession (Same CDS sequence)	NM_031208.3
Accession Version	NM_031208.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 675bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-06-10
Organism	Homo sapiens(human)
Product	acylpyruvase FAHD1, mitochondrial isoform 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL136720.1. On Dec 2, 2008 this sequence version replaced NM_031208.2. Transcript Variant: This variant (2) differs in the 3' UTR and coding sequence compared to variant 1. The resulting isoform (2) has a shorter and distinct C-terminus compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript is intronless :: AL136720.1, AK094199.1 [ECO:0000345] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: reported by MitoCarta ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGGAATCA TGGCAGCATC CAGGCCATTG TCCCGCTTCT GGGAGTGGGG AAAGAACATC 
GTCTGCGTGG GGAGGAACTA CGCGGACCAC GTCAGGGAGA TGCGCAGCGC GGTGTTGAGC 
GAGCCCGTGC TGTTCCTGAA GCCGTCCACG GCCTACGCGC CCGAGGGCTC GCCCATCCTC 
ATGCCCGCGT ACACTCGCAA CCTGCACCAC GAGCTGGAGC TGGGCGTGGT GATGGGCAAG 
CGCTGCCGCG CAGTCCCCGA GGCTGCGGCC ATGGACTACG TGGGCGGCTA TGCCCTGTGC 
CTGGATATGA CCGCCCGGGA CGTGCAGGAC GAGTGCAAGA AGAAGGGGCT GCCCTGGACT 
CTGGCGAAGA GCTTCACGGC GTCCTGCCCG GTCAGCGCGT TCGTGCCCAA GGAGAAGATC 
CCTGACCCTC ACAAGCTGAA GCTCTGGCTC AAGGTCAACG GCGAACTCAG ACAGGAGGGT 
GAGACATCCT CCATGATTTT TTCCATCCCC TACATCATCA GCTATGTTTC TAAGATCATA 
ACCTTGGAAG AAGGAGATAT TATCTTGACT GGGACGCCAA AGGGAGTTGG ACCGGTTAAA 
GAAAACGATG AGATCGAGGC TGGCATACAC GGGCTGGTCA GTATGACATT TAAAGTGGAA 
AAGCCAGAAT ATTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_112485.1
CDS	7..681
Translation	MGIMAASRPLSRFWEWGKNIVCVGRNYADHVREMRSAVLSEPVLFLKPSTAYAPEGSPILMPAYTRNLHHELELGVVMGKRCRAVPEAAAMDYVGGYALCLDMTARDVQDECKKKGLPWTLAKSFTASCPVSAFVPKEKIPDPHKLKLWLKVNGELRQEGETSSMIFSIPYIISYVSKIITLEEGDIILTGTPKGVGPVKENDEIEAGIHGLVSMTFKVEKPEY

Target ORF information:

RefSeq Version	NM_031208.3
Organism	Homo sapiens(human)
Definition	Homo sapiens fumarylacetoacetate hydrolase domain containing 1 (FAHD1), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_031208.3

ORF Insert Sequence:

ATGGGAATCA TGGCAGCATC CAGGCCATTG TCCCGCTTCT GGGAGTGGGG AAAGAACATC 
GTCTGCGTGG GGAGGAACTA CGCGGACCAC GTCAGGGAGA TGCGCAGCGC GGTGTTGAGC 
GAGCCCGTGC TGTTCCTGAA GCCGTCCACG GCCTACGCGC CCGAGGGCTC GCCCATCCTC 
ATGCCCGCGT ACACTCGCAA CCTGCACCAC GAGCTGGAGC TGGGCGTGGT GATGGGCAAG 
CGCTGCCGCG CAGTCCCCGA GGCTGCGGCC ATGGACTACG TGGGCGGCTA TGCCCTGTGC 
CTGGATATGA CCGCCCGGGA CGTGCAGGAC GAGTGCAAGA AGAAGGGGCT GCCCTGGACT 
CTGGCGAAGA GCTTCACGGC GTCCTGCCCG GTCAGCGCGT TCGTGCCCAA GGAGAAGATC 
CCTGACCCTC ACAAGCTGAA GCTCTGGCTC AAGGTCAACG GCGAACTCAG ACAGGAGGGT 
GAGACATCCT CCATGATTTT TTCCATCCCC TACATCATCA GCTATGTTTC TAAGATCATA 
ACCTTGGAAG AAGGAGATAT TATCTTGACT GGGACGCCAA AGGGAGTTGG ACCGGTTAAA 
GAAAACGATG AGATCGAGGC TGGCATACAC GGGCTGGTCA GTATGACATT TAAAGTGGAA 
AAGCCAGAAT ATTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Depletion of oxaloacetate decarboxylase FAHD1 inhibits mitochondrial electron transport and induces cellular senescence in human endothelial cells.
Experimental gerontology927-12(2017 06)
Petit M,Koziel R,Etemad S,Pircher H,Jansen-D?rr P

Identification of FAH domain-containing protein 1 (FAHD1) as oxaloacetate decarboxylase.
The Journal of biological chemistry290(11)6755-62(2015 Mar)
Pircher H,von Grafenstein S,Diener T,Metzger C,Albertini E,Taferner A,Unterluggauer H,Kramer C,Liedl KR,Jansen-D?rr P

FAH domain containing protein 1 (FAHD-1) is required for mitochondrial function and locomotion activity in C. elegans.
PloS one10(8)e0134161(2015)
Taferner A,Pircher H,Koziel R,von Grafenstein S,Baraldo G,Palikaras K,Liedl KR,Tavernarakis N,Jansen-D?rr P

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FAHD1 cDNA ORF clone, Homo sapiens(human)

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gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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