KRTAP1-1 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	KRTAP1-1
Entrez Gene ID	81851
Full Name	keratin associated protein 1-1
Synonyms	HB2A,KAP1.1,KAP1.1A,KAP1.1B,KAP1.6,KAP1.7,KRTAP1.1,KRTAP1A,hKAP1.7
General protein information	Preferred Names keratin associated protein 1-1 Names keratin-associated protein 1-1 high sulfur keratin-associated protein 1.1 keratin associated protein 1.7 keratin associated protein 1A keratin-associated protein 1.1 keratin-associated protein 1.6
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 17 Map Location: 17q21.2
Summary	This protein is a member of the keratin-associated protein (KAP) family. The KAP proteins form a matrix of keratin intermediate filaments which contribute to the structure of hair fibers. KAP family members appear to have unique, family-specific amino- and carboxyl-terminal regions and are subdivided into three multi-gene families according to amino acid composition: the high sulfur, the ultrahigh sulfur, and the high tyrosine/glycine KAPs. This protein is a member of the high sulfur KAP family and the gene is localized to a cluster of KAPs at 17q12-q21. [provided by RefSeq, Jul 2008].
Disorder MIM:	608819

mRNA and Protein(s)

mRNA	Protein	Name
NM_030967.2	NP_112229.1	keratin-associated protein 1-1
NM_030967.3	NP_112229.1	keratin-associated protein 1-1

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	KRTAP1-1	XP_523635.2
Mus musculus (house mouse)	Krtap1-3	NP_001078995.1
Rattus norvegicus (Norway rat)	Krtap1-3	XP_001055744.3
	LOC703076	XP_001102313.2
Canis lupus familiaris (dog)	LOC102151604	XP_005624577.1
Canis lupus familiaris (dog)	LOC102151527	XP_005624576.1
Bos taurus (cattle)	LOC618495	XP_002696018.1
Bos taurus (cattle)	LOC788284	XP_002696060.1
Homo sapiens (human)	KRTAP1-1	NP_112229.1
Canis lupus familiaris (dog)	LOC102151268	XP_005624572.1
Canis lupus familiaris (dog)	LOC102151404	XP_005624574.1
Bos taurus (cattle)	KRTAP1-1	NP_001098839.1
Bos taurus (cattle)	LOC540285	XP_002696019.1

Gene Ontology
Bibliography

Related articles in PubMed

Krtap11-1, a hair keratin-associated protein, as a possible crucial element for the physical properties of hair shafts.
Fujimoto S, Takase T, Kadono N, Maekubo K, Hirai Y
Journal of dermatological science74(1)39-47(2014 Apr)

Polymorphisms in the human high sulfur hair keratin-associated protein 1, KAP1, gene family.
Shimomura Y, Aoki N, Schweizer J, Langbein L, Rogers MA, Winter H, Ito M
The Journal of biological chemistry277(47)45493-501(2002 Nov)

hKAP1.6 and hKAP1.7, two novel human high sulfur keratin-associated proteins are expressed in the hair follicle cortex.
Shimomura Y, Aoki N, Rogers MA, Langbein L, Schweizer J, Ito M
The Journal of investigative dermatology118(2)226-31(2002 Feb)

Characterization of a cluster of human high/ultrahigh sulfur keratin-associated protein genes embedded in the type I keratin gene domain on chromosome 17q12-21.
Rogers MA, Langbein L, Winter H, Ehmann C, Praetzel S, Korn B, Schweizer J
The Journal of biological chemistry276(22)19440-51(2001 Jun)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Krtap11-1 may play an important role on keratin-bundle assembly in the hair cortex.
Title: Krtap11-1, a hair keratin-associated protein, as a possible crucial element for the physical properties of hair shafts.

polymorphisms in Japanese and Caucasian individuals
Title: Polymorphisms in the human high sulfur hair keratin-associated protein 1, KAP1, gene family.

The following KRTAP1-1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the KRTAP1-1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu29158	NM_030967.3 Latest version!	Homo sapiens keratin associated protein 1-1 (KRTAP1-1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
View Old Accession Versions >>
OHu29158	NM_030967.2	Homo sapiens keratin associated protein 1-1 (KRTAP1-1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
Hide Old Accession Versions >>

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

KRTAP1-1 ( NM_030967.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_112229.1 Homo sapiens keratin associated protein 1-1 (KRTAP1-1), mRNA.

Price & Availability↑

CloneID	OHu29158
Clone ID Related Accession (Same CDS sequence)	NM_030967.2 , NM_030967.3
Accession Version	NM_030967.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 534bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-09-30
Organism	Homo sapiens(human)
Product	keratin-associated protein 1-1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff in collaboration with Michael Rogers. The reference sequence was derived from AB052934.1. This sequence is a reference standard in the RefSeqGene project. On Sep 14, 2001 this sequence version replaced NM_030967.1. ##Evidence-Data-START## Transcript is intronless :: AB052934.1 [ECO:0000345] ##Evidence-Data-END##

ATGGCCTGCT GTCAGACCAG CTTCTGTGGA TTTCCCAGCT GCTCCACCAG TGGGACCTGC 
GGCTCCAGCT GCTGCCAGCC AAGCTGCTGT GAGACCAGCT CCTGCCAGCC ACGCTGCTGT 
GAGACCAGCT GCTGCCAGCC AAGCTGCTGC CAGACCAGCT TCTGTGGATT TCCTAGCTTC 
TCAACCGGTG GGACTTGTGA CTCTAGCTGC TGCCAGCCAA GCTGCTGTGA AACTAGCTGC 
TGCCAGCCAA GCTGCTACCA GACCAGCTCC TGCGGAACTG GCTGTGGCAT TGGTGGTGGC 
ATTGGCTATG GCCAGGAGGG CAGCAGTGGA GCTGTGAGCA CCCGTATCAG GTGGTGCCGC 
CCAGACTGCC GTGTGGAGGG TACCTGCCTG CCCCCCTGCT GCGTGGTGAG CTGCACACCC 
CCATCCTGCT GCCAGCTGCA CCACGCCGAG GCCTCCTGCT GCCGCCCATC CTACTGTGGA 
CAGTCCTGTT GCCGCCCAGT CTGCTGCTGC TACTGCTCTG AGCCCACTTG TTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_112229.1
CDS	65..598
Translation	MACCQTSFCGFPSCSTSGTCGSSCCQPSCCETSSCQPRCCETSCCQPSCCQTSFCGFPSFSTGGTCDSSCCQPSCCETSCCQPSCYQTSSCGTGCGIGGGIGYGQEGSSGAVSTRIRWCRPDCRVEGTCLPPCCVVSCTPPSCCQLHHAEASCCRPSYCGQSCCRPVCCCYCSEPTC

Target ORF information:

RefSeq Version	NM_030967.2
Organism	Homo sapiens(human)
Definition	Homo sapiens keratin associated protein 1-1 (KRTAP1-1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_030967.2

ORF Insert Sequence:

ATGGCCTGCT GTCAGACCAG CTTCTGTGGA TTTCCCAGCT GCTCCACCAG TGGGACCTGC 
GGCTCCAGCT GCTGCCAGCC AAGCTGCTGT GAGACCAGCT CCTGCCAGCC ACGCTGCTGT 
GAGACCAGCT GCTGCCAGCC AAGCTGCTGC CAGACCAGCT TCTGTGGATT TCCTAGCTTC 
TCAACCGGTG GGACTTGTGA CTCTAGCTGC TGCCAGCCAA GCTGCTGTGA AACTAGCTGC 
TGCCAGCCAA GCTGCTACCA GACCAGCTCC TGCGGAACTG GCTGTGGCAT TGGTGGTGGC 
ATTGGCTATG GCCAGGAGGG CAGCAGTGGA GCTGTGAGCA CCCGTATCAG GTGGTGCCGC 
CCAGACTGCC GTGTGGAGGG TACCTGCCTG CCCCCCTGCT GCGTGGTGAG CTGCACACCC 
CCATCCTGCT GCCAGCTGCA CCACGCCGAG GCCTCCTGCT GCCGCCCATC CTACTGTGGA 
CAGTCCTGTT GCCGCCCAGT CTGCTGCTGC TACTGCTCTG AGCCCACTTG TTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

KRTAP1-1 ( NM_030967.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_112229.1 Homo sapiens keratin associated protein 1-1 (KRTAP1-1), mRNA.

Price & Availability↑

CloneID	OHu29158
Clone ID Related Accession (Same CDS sequence)	NM_030967.2 , NM_030967.3
Accession Version	NM_030967.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 534bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-21
Organism	Homo sapiens(human)
Product	keratin-associated protein 1-1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff in collaboration with Michael Rogers. The reference sequence was derived from AB052934.1 and AC007455.7. This sequence is a reference standard in the RefSeqGene project. On Nov 23, 2018 this sequence version replaced NM_030967.2. ##Evidence-Data-START## Transcript is intronless :: AB052934.1, AJ406926.1 [ECO:0000345] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000306271.5/ ENSP00000305975.4 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGCCTGCT GTCAGACCAG CTTCTGTGGA TTTCCCAGCT GCTCCACCAG TGGGACCTGC 
GGCTCCAGCT GCTGCCAGCC AAGCTGCTGT GAGACCAGCT CCTGCCAGCC ACGCTGCTGT 
GAGACCAGCT GCTGCCAGCC AAGCTGCTGC CAGACCAGCT TCTGTGGATT TCCTAGCTTC 
TCAACCGGTG GGACTTGTGA CTCTAGCTGC TGCCAGCCAA GCTGCTGTGA AACTAGCTGC 
TGCCAGCCAA GCTGCTACCA GACCAGCTCC TGCGGAACTG GCTGTGGCAT TGGTGGTGGC 
ATTGGCTATG GCCAGGAGGG CAGCAGTGGA GCTGTGAGCA CCCGTATCAG GTGGTGCCGC 
CCAGACTGCC GTGTGGAGGG TACCTGCCTG CCCCCCTGCT GCGTGGTGAG CTGCACACCC 
CCATCCTGCT GCCAGCTGCA CCACGCCGAG GCCTCCTGCT GCCGCCCATC CTACTGTGGA 
CAGTCCTGTT GCCGCCCAGT CTGCTGCTGC TACTGCTCTG AGCCCACTTG TTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_112229.1
CDS	54..587
Translation	MACCQTSFCGFPSCSTSGTCGSSCCQPSCCETSSCQPRCCETSCCQPSCCQTSFCGFPSFSTGGTCDSSCCQPSCCETSCCQPSCYQTSSCGTGCGIGGGIGYGQEGSSGAVSTRIRWCRPDCRVEGTCLPPCCVVSCTPPSCCQLHHAEASCCRPSYCGQSCCRPVCCCYCSEPTC

Target ORF information:

RefSeq Version	NM_030967.3
Organism	Homo sapiens(human)
Definition	Homo sapiens keratin associated protein 1-1 (KRTAP1-1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_030967.3

ORF Insert Sequence:

ATGGCCTGCT GTCAGACCAG CTTCTGTGGA TTTCCCAGCT GCTCCACCAG TGGGACCTGC 
GGCTCCAGCT GCTGCCAGCC AAGCTGCTGT GAGACCAGCT CCTGCCAGCC ACGCTGCTGT 
GAGACCAGCT GCTGCCAGCC AAGCTGCTGC CAGACCAGCT TCTGTGGATT TCCTAGCTTC 
TCAACCGGTG GGACTTGTGA CTCTAGCTGC TGCCAGCCAA GCTGCTGTGA AACTAGCTGC 
TGCCAGCCAA GCTGCTACCA GACCAGCTCC TGCGGAACTG GCTGTGGCAT TGGTGGTGGC 
ATTGGCTATG GCCAGGAGGG CAGCAGTGGA GCTGTGAGCA CCCGTATCAG GTGGTGCCGC 
CCAGACTGCC GTGTGGAGGG TACCTGCCTG CCCCCCTGCT GCGTGGTGAG CTGCACACCC 
CCATCCTGCT GCCAGCTGCA CCACGCCGAG GCCTCCTGCT GCCGCCCATC CTACTGTGGA 
CAGTCCTGTT GCCGCCCAGT CTGCTGCTGC TACTGCTCTG AGCCCACTTG TTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Krtap11-1, a hair keratin-associated protein, as a possible crucial element for the physical properties of hair shafts.
Journal of dermatological science74(1)39-47(2014 Apr)
Fujimoto S,Takase T,Kadono N,Maekubo K,Hirai Y

Polymorphisms in the human high sulfur hair keratin-associated protein 1, KAP1, gene family.
The Journal of biological chemistry277(47)45493-501(2002 Nov)
Shimomura Y,Aoki N,Schweizer J,Langbein L,Rogers MA,Winter H,Ito M

hKAP1.6 and hKAP1.7, two novel human high sulfur keratin-associated proteins are expressed in the hair follicle cortex.
The Journal of investigative dermatology118(2)226-31(2002 Feb)
Shimomura Y,Aoki N,Rogers MA,Langbein L,Schweizer J,Ito M

Characterization of a cluster of human high/ultrahigh sulfur keratin-associated protein genes embedded in the type I keratin gene domain on chromosome 17q12-21.
The Journal of biological chemistry276(22)19440-51(2001 Jun)
Rogers MA,Langbein L,Winter H,Ehmann C,Praetzel S,Korn B,Schweizer J

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KRTAP1-1 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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