KRTAP1-3 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	KRTAP1-3
Entrez Gene ID	81850
Full Name	keratin associated protein 1-3
Synonyms	KAP1.2,KAP1.3,KAP1.6,KAP1.8A,KAP1.8B,KAP1.9,KRTAP1.3
General protein information	Preferred Names keratin associated protein 1-3 Names keratin-associated protein 1-3 keratin associated protein 1.6 keratin-associated protein 1.8 keratin-associated protein 1.9
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 17 Map Location: 17q21.2
Summary	This protein is a member of the keratin-associated protein (KAP) family. The KAP proteins form a matrix of keratin intermediate filaments which contribute to the structure of hair fibers. KAP family members appear to have unique, family-specific amino- and carboxyl-terminal regions and are subdivided into three multi-gene families according to amino acid composition: the high sulfur, the ultrahigh sulfur, and the high tyrosine/glycine KAPs. This protein is a member of the high sulfur KAP family and the gene is localized to a cluster of KAPs at 17q12-q21. [provided by RefSeq, Jul 2008].
Disorder MIM:	608820

mRNA and Protein(s)

mRNA	Protein	Name
NM_030966.2	NP_112228.1	keratin-associated protein 1-3
NM_030966.1	NP_112228.1	keratin-associated protein 1-3

Pathways from BioSystems

Homologies

Homo sapiens (human)	KRTAP1-3	NP_112228.1
Pan troglodytes (chimpanzee)	LOC743364	XP_001147177.2
Mus musculus (house mouse)	Krtap9-3	NP_083627.2

Gene Ontology
Bibliography

Related articles in PubMed

Polymorphisms in the human high sulfur hair keratin-associated protein 1, KAP1, gene family.
Shimomura Y, Aoki N, Schweizer J, Langbein L, Rogers MA, Winter H, Ito M
The Journal of biological chemistry277(47)45493-501(2002 Nov)

Characterization of a cluster of human high/ultrahigh sulfur keratin-associated protein genes embedded in the type I keratin gene domain on chromosome 17q12-21.
Rogers MA, Langbein L, Winter H, Ehmann C, Praetzel S, Korn B, Schweizer J
The Journal of biological chemistry276(22)19440-51(2001 Jun)

[Cloning and structural characteristics of human hair keratin genes rich in sulfur].
Zhumabaeva BD, Gening LV, Gazarian KG
Molekuliarnaia biologiia26(4)813-20(1992 Jul-Aug)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

polymorphisms in Japanese and Caucasian individuals
Title: Polymorphisms in the human high sulfur hair keratin-associated protein 1, KAP1, gene family.

The following KRTAP1-3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the KRTAP1-3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu29111	NM_030966.2 Latest version!	Homo sapiens keratin associated protein 1-3 (KRTAP1-3), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
View Old Accession Versions >>
OHu29111	NM_030966.1	Homo sapiens keratin associated protein 1-3 (KRTAP1-3), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

KRTAP1-3 ( NM_030966.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_112228.1 Homo sapiens keratin associated protein 1-3 (KRTAP1-3), mRNA.

Price & Availability↑

CloneID	OHu29111
Clone ID Related Accession (Same CDS sequence)	NM_030966.2 , NM_030966.1
Accession Version	NM_030966.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 504bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-20
Organism	Homo sapiens(human)
Product	keratin-associated protein 1-3
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff in collaboration with Michael Rogers. The reference sequence was derived from AC007455.7 and AJ406927.1. On May 17, 2019 this sequence version replaced NM_030966.1. ##Evidence-Data-START## Transcript is intronless :: AJ406927.1, BC069161.1 [ECO:0000345] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000344363.7/ ENSP00000344420.5 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGACCTGCT GCCAGACCAG CTTCTGTGGA TATCCCAGCT GCTCCACCAG TGGGACATGC 
GGCTCCAGCT GCTGCCAGCC AAGCTGCTGT GAGACCAGCT GCTGCCAGCC AAGCTGCTGC 
CAGACCAGCT TCTGCGGATT TCCTAGCTTC TCAACTAGTG GGACCTGCAG CTCCAGTTGC 
TGCCAGCCAA GCTGCTGTGA GACCAGCTGC TGCCAGCCAA GCTGCTGCCA GACCAGCTCC 
TGCGGAACTG GCTGTGGCAT TGGTGGTGGC ATTGGCTATG GCCAGGAGGG CAGCAGTGGA 
GCTGTGAGCA CCCGTATCAG GTGGTGCCGC CCAGACTGCC GTGTGGAGGG TACCTGCCTG 
CCCCCCTGCT GTGTGGTGAG CTGCACACCC CCAACCTGCT GCCAGCTGCA CCACGCCGAG 
GCCTCCTGCT GCCGCCCATC CTACTGTGGA CAGTCCTGCT GCCGCCCAGT CTGCTGCTGC 
TACTCCTGTG AGCCCACCTG CTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_112228.1
CDS	54..557
Translation	MTCCQTSFCGYPSCSTSGTCGSSCCQPSCCETSCCQPSCCQTSFCGFPSFSTSGTCSSSCCQPSCCETSCCQPSCCQTSSCGTGCGIGGGIGYGQEGSSGAVSTRIRWCRPDCRVEGTCLPPCCVVSCTPPTCCQLHHAEASCCRPSYCGQSCCRPVCCCYSCEPTC

Target ORF information:

RefSeq Version	NM_030966.2
Organism	Homo sapiens(human)
Definition	Homo sapiens keratin associated protein 1-3 (KRTAP1-3), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_030966.2

ORF Insert Sequence:

ATGACCTGCT GCCAGACCAG CTTCTGTGGA TATCCCAGCT GCTCCACCAG TGGGACATGC 
GGCTCCAGCT GCTGCCAGCC AAGCTGCTGT GAGACCAGCT GCTGCCAGCC AAGCTGCTGC 
CAGACCAGCT TCTGCGGATT TCCTAGCTTC TCAACTAGTG GGACCTGCAG CTCCAGTTGC 
TGCCAGCCAA GCTGCTGTGA GACCAGCTGC TGCCAGCCAA GCTGCTGCCA GACCAGCTCC 
TGCGGAACTG GCTGTGGCAT TGGTGGTGGC ATTGGCTATG GCCAGGAGGG CAGCAGTGGA 
GCTGTGAGCA CCCGTATCAG GTGGTGCCGC CCAGACTGCC GTGTGGAGGG TACCTGCCTG 
CCCCCCTGCT GTGTGGTGAG CTGCACACCC CCAACCTGCT GCCAGCTGCA CCACGCCGAG 
GCCTCCTGCT GCCGCCCATC CTACTGTGGA CAGTCCTGCT GCCGCCCAGT CTGCTGCTGC 
TACTCCTGTG AGCCCACCTG CTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

KRTAP1-3 ( NM_030966.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_112228.1 Homo sapiens keratin associated protein 1-3 (KRTAP1-3), mRNA.

Price & Availability↑

CloneID	OHu29111
Clone ID Related Accession (Same CDS sequence)	NM_030966.2 , NM_030966.1
Accession Version	NM_030966.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 504bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-13
Organism	Homo sapiens(human)
Product	keratin-associated protein 1-3
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff in collaboration with Michael Rogers. The reference sequence was derived from AJ406927.1. ##Evidence-Data-START## Transcript is intronless :: AJ406927.1 [ECO:0000345] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGACCTGCT GCCAGACCAG CTTCTGTGGA TATCCCAGCT GCTCCACCAG TGGGACATGC 
GGCTCCAGCT GCTGCCAGCC AAGCTGCTGT GAGACCAGCT GCTGCCAGCC AAGCTGCTGC 
CAGACCAGCT TCTGCGGATT TCCTAGCTTC TCAACTAGTG GGACCTGCAG CTCCAGTTGC 
TGCCAGCCAA GCTGCTGTGA GACCAGCTGC TGCCAGCCAA GCTGCTGCCA GACCAGCTCC 
TGCGGAACTG GCTGTGGCAT TGGTGGTGGC ATTGGCTATG GCCAGGAGGG CAGCAGTGGA 
GCTGTGAGCA CCCGTATCAG GTGGTGCCGC CCAGACTGCC GTGTGGAGGG TACCTGCCTG 
CCCCCCTGCT GTGTGGTGAG CTGCACACCC CCAACCTGCT GCCAGCTGCA CCACGCCGAG 
GCCTCCTGCT GCCGCCCATC CTACTGTGGA CAGTCCTGCT GCCGCCCAGT CTGCTGCTGC 
TACTCCTGTG AGCCCACCTG CTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_112228.1
CDS	35..538
Translation	MTCCQTSFCGYPSCSTSGTCGSSCCQPSCCETSCCQPSCCQTSFCGFPSFSTSGTCSSSCCQPSCCETSCCQPSCCQTSSCGTGCGIGGGIGYGQEGSSGAVSTRIRWCRPDCRVEGTCLPPCCVVSCTPPTCCQLHHAEASCCRPSYCGQSCCRPVCCCYSCEPTC

Target ORF information:

RefSeq Version	NM_030966.1
Organism	Homo sapiens(human)
Definition	Homo sapiens keratin associated protein 1-3 (KRTAP1-3), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_030966.1

ORF Insert Sequence:

ATGACCTGCT GCCAGACCAG CTTCTGTGGA TATCCCAGCT GCTCCACCAG TGGGACATGC 
GGCTCCAGCT GCTGCCAGCC AAGCTGCTGT GAGACCAGCT GCTGCCAGCC AAGCTGCTGC 
CAGACCAGCT TCTGCGGATT TCCTAGCTTC TCAACTAGTG GGACCTGCAG CTCCAGTTGC 
TGCCAGCCAA GCTGCTGTGA GACCAGCTGC TGCCAGCCAA GCTGCTGCCA GACCAGCTCC 
TGCGGAACTG GCTGTGGCAT TGGTGGTGGC ATTGGCTATG GCCAGGAGGG CAGCAGTGGA 
GCTGTGAGCA CCCGTATCAG GTGGTGCCGC CCAGACTGCC GTGTGGAGGG TACCTGCCTG 
CCCCCCTGCT GTGTGGTGAG CTGCACACCC CCAACCTGCT GCCAGCTGCA CCACGCCGAG 
GCCTCCTGCT GCCGCCCATC CTACTGTGGA CAGTCCTGCT GCCGCCCAGT CTGCTGCTGC 
TACTCCTGTG AGCCCACCTG CTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Polymorphisms in the human high sulfur hair keratin-associated protein 1, KAP1, gene family.
The Journal of biological chemistry277(47)45493-501(2002 Nov)
Shimomura Y,Aoki N,Schweizer J,Langbein L,Rogers MA,Winter H,Ito M

Characterization of a cluster of human high/ultrahigh sulfur keratin-associated protein genes embedded in the type I keratin gene domain on chromosome 17q12-21.
The Journal of biological chemistry276(22)19440-51(2001 Jun)
Rogers MA,Langbein L,Winter H,Ehmann C,Praetzel S,Korn B,Schweizer J

[Cloning and structural characteristics of human hair keratin genes rich in sulfur].
Molekuliarnaia biologiia26(4)813-20(1992 Jul-Aug)
Zhumabaeva BD,Gening LV,Gazarian KG

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KRTAP1-3 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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