ADAMTS10 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	ADAMTS10
Entrez Gene ID	81794
Full Name	ADAM metallopeptidase with thrombospondin type 1 motif 10
Synonyms	ADAM-TS10,ADAMTS-10,WMS,WMS1
General protein information	Preferred Names ADAM metallopeptidase with thrombospondin type 1 motif 10 Names A disintegrin and metalloproteinase with thrombospondin motifs 10 ADAM-TS 10 a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 10 zinc metalloendopeptidase
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 19 Map Location: 19p13.2
Summary	This gene belongs to the ADAMTS (a disintegrin and metalloproteinase domain with thrombospondin type-1 motifs) family of zinc-dependent proteases. ADAMTS proteases are complex secreted enzymes containing a prometalloprotease domain of the reprolysin type attached to an ancillary domain with a highly conserved structure that includes at least one thrombospondin type 1 repeat. They have been demonstrated to have important roles in connective tissue organization, coagulation, inflammation, arthritis, angiogenesis and cell migration. The product of this gene plays a major role in growth and in skin, lens, and heart development. It is also a candidate gene for autosomal recessive Weill-Marchesani syndrome. [provided by RefSeq, Jul 2008].
Disorder MIM:	608990
Disorder Html:	Weill-Marchesani syndrome 1, recessive, 277600 (3)

mRNA and Protein(s)

mRNA	Protein	Name
XM_017027340.1	XP_016882829.1	A disintegrin and metalloproteinase with thrombospondin motifs 10 isoform X4
NM_030957.4	NP_112219.3	A disintegrin and metalloproteinase with thrombospondin motifs 10 isoform 1 preproprotein
NM_001282352.1	NP_001269281.1	A disintegrin and metalloproteinase with thrombospondin motifs 10 isoform 2
XM_017027339.1	XP_016882828.1	A disintegrin and metalloproteinase with thrombospondin motifs 10 isoform X3
XM_017027338.1	XP_016882827.1	A disintegrin and metalloproteinase with thrombospondin motifs 10 isoform X1
XM_017027338.2	XP_016882827.1	A disintegrin and metalloproteinase with thrombospondin motifs 10 isoform X1
NM_030957.3	NP_112219.3	A disintegrin and metalloproteinase with thrombospondin motifs 10 isoform 1 preproprotein
XM_006722917.3	XP_006722980.1	A disintegrin and metalloproteinase with thrombospondin motifs 10 isoform X2

Pathways from BioSystems

Homologies

Homo sapiens (human)	ADAMTS10	NP_112219.3
Bos taurus (cattle)	ADAMTS10	NP_001192679.1
Gallus gallus (chicken)	ADAMTS10	XP_001232250.1
Canis lupus familiaris (dog)	ADAMTS10	XP_854320.1
	ADAMTS10	XP_001095217.1
Xenopus tropicalis (tropical clawed frog)	adamts10	XP_002938612.2
Pan troglodytes (chimpanzee)	ADAMTS10	XP_001159753.1
Mus musculus (house mouse)	Adamts10	NP_766207.2
Rattus norvegicus (Norway rat)	Adamts10	NP_001258374.1
Danio rerio (zebrafish)	adamts10	NP_001116746.1

Gene Ontology
Bibliography

Related articles in PubMed

ADAMTS-10 and -6 differentially regulate cell-cell junctions and focal adhesions.
Cain SA, Mularczyk EJ, Singh M, Massam-Wu T, Kielty CM
Scientific reports635956(2016 Oct)

Screening ADAMTS10 in dog populations supports Gly661Arg as the glaucoma-causing variant in beagles.
Kuchtey J, Kunkel J, Esson D, Sapienza JS, Ward DA, Plummer CE, Gelatt KN, Kuchtey RW
Investigative ophthalmology & visual science54(3)1881-6(2013 Mar)

SuperTAG methylation-specific digital karyotyping reveals uremia-induced epigenetic dysregulation of atherosclerosis-related genes.
Zawada AM, Rogacev KS, Hummel B, Gr?n OS, Friedrich A, Rotter B, Winter P, Geisel J, Fliser D, Heine GH
Circulation. Cardiovascular genetics5(6)611-20(2012 Dec)

ADAMTS10 protein interacts with fibrillin-1 and promotes its deposition in extracellular matrix of cultured fibroblasts.
Kutz WE, Wang LW, Bader HL, Majors AK, Iwata K, Traboulsi EI, Sakai LY, Keene DR, Apte SS
The Journal of biological chemistry286(19)17156-67(2011 May)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

These findings support the Gly661Arg mutation of ADAMTS10 as the likely cause of POAG in beagles.
Title: Screening ADAMTS10 in dog populations supports Gly661Arg as the glaucoma-causing variant in beagles.

ADAMTS10 participates in microfibril biogenesis rather than in fibrillin-1 turnover
Title: ADAMTS10 protein interacts with fibrillin-1 and promotes its deposition in extracellular matrix of cultured fibroblasts.

Homozygous mutation in ADAMTS10 causes lenticular myopia, ectopia lentis, glaucoma, spherophakia, and short stature.
Title: Homozygous mutations in ADAMTS10 and ADAMTS17 cause lenticular myopia, ectopia lentis, glaucoma, spherophakia, and short stature.

Mutations in ADAMTS10 gene is not responsible for microspherophakia.
Title: Clinical and genetic investigation of isolated microspherophakia in a consanguineous Tunisian family.

infer that folding of the complex C-terminal ancillary domain is the rate-limiting step in biosynthesis of ADAMTS10, and that it (but not catalytic domain) is sensitive to subtle changes in efficiency of signal peptide cleavage.
Title: Functional analysis of an ADAMTS10 signal peptide mutation in Weill-Marchesani syndrome demonstrates a long-range effect on secretion of the full-length enzyme.

The following ADAMTS10 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the ADAMTS10 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu20533	NM_001282352.1 Latest version!	Homo sapiens ADAM metallopeptidase with thrombospondin type 1 motif 10 (ADAMTS10), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
OHu51850	XM_006722917.3 Latest version!	Homo sapiens ADAM metallopeptidase with thrombospondin type 1 motif 10 (ADAMTS10), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$391.30 $559.00
OHu88745	XM_017027339.1 Latest version!	Homo sapiens ADAM metallopeptidase with thrombospondin type 1 motif 10 (ADAMTS10), transcript variant X4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00
OHu88746	XM_017027340.1 Latest version!	Homo sapiens ADAM metallopeptidase with thrombospondin type 1 motif 10 (ADAMTS10), transcript variant X5, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00
OHu20510	NM_030957.4 Latest version!	Homo sapiens ADAM metallopeptidase with thrombospondin type 1 motif 10 (ADAMTS10), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	20	$776.30 $1109.00
OHu20510	XM_017027338.2 Latest version!	Homo sapiens ADAM metallopeptidase with thrombospondin type 1 motif 10 (ADAMTS10), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	20	$776.30 $1109.00
View Old Accession Versions >>
OHu20510	XM_017027338.1	Homo sapiens ADAM metallopeptidase with thrombospondin type 1 motif 10 (ADAMTS10), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	20	$776.30 $1109.00
OHu20510	NM_030957.3	Homo sapiens ADAM metallopeptidase with thrombospondin type 1 motif 10 (ADAMTS10), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	20	$776.30 $1109.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

ADAMTS10 ( NM_001282352.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001269281.1 Homo sapiens ADAM metallopeptidase with thrombospondin type 1 motif 10 (ADAMTS10), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu20533
Clone ID Related Accession (Same CDS sequence)	NM_001282352.1
Accession Version	NM_001282352.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1773bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-15
Organism	Homo sapiens(human)
Product	A disintegrin and metalloproteinase with thrombospondin motifs 10 isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK131414.1, AF163762.1, BC029308.1, AC130469.2 and BF510205.1. On or before Aug 31, 2013 this sequence version replaced XM_005272501.1, XM_005277799.1. Transcript Variant: This variant (2) lacks several exons, uses an alternate 5'-terminal exon, and initiates translation at an alternate start codon, compared to variant 1. The encoded isoform (2) has a shorter and distinct N-terminus, compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK131414.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGGGCCGA CGAGTGTCCT CCGGGCTGGA CTCACTCCTT CCTGTCTCCC CCCACCCAGT 
GGTGCTACAA ACGGGTCTGT GTCCCCTTTG GGTCGCGCCC AGAGGGTGTG GACGGAGCCT 
GGGGGCCGTG GACTCCATGG GGCGACTGCA GCCGGACCTG TGGCGGCGGC GTGTCCTCTT 
CTAGCCGTCA CTGCGACAGC CCCAGGCCAA CCATCGGGGG CAAGTACTGT CTGGGTGAGA 
GAAGGCGGCA CCGCTCCTGC AACACGGATG ACTGTCCCCC TGGCTCCCAG GACTTCAGAG 
AAGTGCAGTG TTCTGAATTT GACAGCATCC CTTTCCGTGG GAAATTCTAC AAGTGGAAAA 
CGTACCGGGG AGGCCTGCTC GCTCACGTGC CTAGCGGAAG GCTTCAACTT CTACACGGAG 
AGGGCGGCAG CCGTGGTGGA CGGGACACCC TGCCGTCCAG ACACGGTGGA CATTTGCGTC 
AGTGGCGAAT GCAAGCACGT GGGCTGCGAC CGAGTCCTGG GCTCCGACCT GCGGGAGGAC 
AAGTGCCGAG TGTGTGGCGG TGACGGCAGT GCCTGCGAGA CCATCGAGGG CGTCTTCAGC 
CCAGCCTCAC CTGGGGCCGG GTACGAGGAT GTCGTCTGGA TTCCCAAAGG CTCCGTCCAC 
ATCTTCATCC AGGATCTGAA CCTCTCTCTC AGTCACTTGG CCCTGAAGGG AGACCAGGAG 
TCCCTGCTGC TGGAGGGGCT GCCTGGGACC CCCCAGCCCC ACCGTCTGCC TCTAGCTGGG 
ACCACCTTTC AACTGCGACA GGGGCCAGAC CAGGTCCAGA GCCTCGAAGC CCTGGGACCG 
ATTAATGCAT CTCTCATCGT CATGGTGCTG GCCCGGACCG AGCTGCCTGC CCTCCGCTAC 
CGCTTCAATG CCCCCATCGC CCGTGACTCG CTGCCCCCCT ACTCCTGGCA CTATGCGCCC 
TGGACCAAGT GCTCGGCCCA GTGTGCAGGC GGTAGCCAGG TGCAGGCGGT GGAGTGCCGC 
AACCAGCTGG ACAGCTCCGC GGTCGCCCCC CACTACTGCA GTGCCCACAG CAAGCTGCCC 
AAAAGGCAGC GCGCCTGCAA CACGGAGCCT TGCCCTCCAG ACTGGGTTGT AGGGAACTGG 
TCGCTCTGCA GCCGCAGCTG CGATGCAGGC GTGCGCAGCC GCTCGGTCGT GTGCCAGCGC 
CGCGTCTCTG CCGCGGAGGA GAAGGCGCTG GACGACAGCG CATGCCCGCA GCCGCGCCCA 
CCTGTACTGG AGGCCTGCCA CGGCCCCACT TGCCCTCCGG AGTGGGCGGC CCTCGACTGG 
TCTGAGTGCA CCCCCAGCTG CGGGCCGGGC CTCCGCCACC GCGTGGTCCT TTGCAAGAGC 
GCAGACCACC GCGCCACGCT GCCCCCGGCG CACTGCTCAC CCGCCGCCAA GCCACCGGCC 
ACCATGCGCT GCAACTTGCG CCGCTGCCCC CCGGCCCGCT GGGTGGCTGG CGAGTGGGGT 
GAGTGCTCTG CACAGTGCGG CGTCGGGCAG CGGCAGCGCT CGGTGCGCTG CACCAGCCAC 
ACGGGCCAGG CGTCGCACGA GTGCACGGAG GCCCTGCGGC CGCCCACCAC GCAGCAGTGT 
GAGGCCAAGT GCGACAGCCC AACCCCCGGG GACGGCCCTG AAGAGTGCAA GGATGTGAAC 
AAGGTCGCCT ACTGCCCCCT GGTGCTCAAA TTTCAGTTCT GCAGCCGAGC CTACTTCCGC 
CAGATGTGCT GCAAAACCTG CCATGGCCAC TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001269281.1
CDS	35..1807
Translation	MGPTSVLRAGLTPSCLPPPSGATNGSVSPLGRAQRVWTEPGGRGLHGATAAGPVAAACPLLAVTATAPGQPSGASTVWVREGGTAPATRMTVPLAPRTSEKCSVLNLTASLSVGNSTSGKRTGEACSLTCLAEGFNFYTERAAAVVDGTPCRPDTVDICVSGECKHVGCDRVLGSDLREDKCRVCGGDGSACETIEGVFSPASPGAGYEDVVWIPKGSVHIFIQDLNLSLSHLALKGDQESLLLEGLPGTPQPHRLPLAGTTFQLRQGPDQVQSLEALGPINASLIVMVLARTELPALRYRFNAPIARDSLPPYSWHYAPWTKCSAQCAGGSQVQAVECRNQLDSSAVAPHYCSAHSKLPKRQRACNTEPCPPDWVVGNWSLCSRSCDAGVRSRSVVCQRRVSAAEEKALDDSACPQPRPPVLEACHGPTCPPEWAALDWSECTPSCGPGLRHRVVLCKSADHRATLPPAHCSPAAKPPATMRCNLRRCPPARWVAGEWGECSAQCGVGQRQRSVRCTSHTGQASHECTEALRPPTTQQCEAKCDSPTPGDGPEECKDVNKVAYCPLVLKFQFCSRAYFRQMCCKTCHGH

Target ORF information:

RefSeq Version	NM_001282352.1
Organism	Homo sapiens(human)
Definition	Homo sapiens ADAM metallopeptidase with thrombospondin type 1 motif 10 (ADAMTS10), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001282352.1

ORF Insert Sequence:

ATGGGGCCGA CGAGTGTCCT CCGGGCTGGA CTCACTCCTT CCTGTCTCCC CCCACCCAGT 
GGTGCTACAA ACGGGTCTGT GTCCCCTTTG GGTCGCGCCC AGAGGGTGTG GACGGAGCCT 
GGGGGCCGTG GACTCCATGG GGCGACTGCA GCCGGACCTG TGGCGGCGGC GTGTCCTCTT 
CTAGCCGTCA CTGCGACAGC CCCAGGCCAA CCATCGGGGG CAAGTACTGT CTGGGTGAGA 
GAAGGCGGCA CCGCTCCTGC AACACGGATG ACTGTCCCCC TGGCTCCCAG GACTTCAGAG 
AAGTGCAGTG TTCTGAATTT GACAGCATCC CTTTCCGTGG GAAATTCTAC AAGTGGAAAA 
CGTACCGGGG AGGCCTGCTC GCTCACGTGC CTAGCGGAAG GCTTCAACTT CTACACGGAG 
AGGGCGGCAG CCGTGGTGGA CGGGACACCC TGCCGTCCAG ACACGGTGGA CATTTGCGTC 
AGTGGCGAAT GCAAGCACGT GGGCTGCGAC CGAGTCCTGG GCTCCGACCT GCGGGAGGAC 
AAGTGCCGAG TGTGTGGCGG TGACGGCAGT GCCTGCGAGA CCATCGAGGG CGTCTTCAGC 
CCAGCCTCAC CTGGGGCCGG GTACGAGGAT GTCGTCTGGA TTCCCAAAGG CTCCGTCCAC 
ATCTTCATCC AGGATCTGAA CCTCTCTCTC AGTCACTTGG CCCTGAAGGG AGACCAGGAG 
TCCCTGCTGC TGGAGGGGCT GCCTGGGACC CCCCAGCCCC ACCGTCTGCC TCTAGCTGGG 
ACCACCTTTC AACTGCGACA GGGGCCAGAC CAGGTCCAGA GCCTCGAAGC CCTGGGACCG 
ATTAATGCAT CTCTCATCGT CATGGTGCTG GCCCGGACCG AGCTGCCTGC CCTCCGCTAC 
CGCTTCAATG CCCCCATCGC CCGTGACTCG CTGCCCCCCT ACTCCTGGCA CTATGCGCCC 
TGGACCAAGT GCTCGGCCCA GTGTGCAGGC GGTAGCCAGG TGCAGGCGGT GGAGTGCCGC 
AACCAGCTGG ACAGCTCCGC GGTCGCCCCC CACTACTGCA GTGCCCACAG CAAGCTGCCC 
AAAAGGCAGC GCGCCTGCAA CACGGAGCCT TGCCCTCCAG ACTGGGTTGT AGGGAACTGG 
TCGCTCTGCA GCCGCAGCTG CGATGCAGGC GTGCGCAGCC GCTCGGTCGT GTGCCAGCGC 
CGCGTCTCTG CCGCGGAGGA GAAGGCGCTG GACGACAGCG CATGCCCGCA GCCGCGCCCA 
CCTGTACTGG AGGCCTGCCA CGGCCCCACT TGCCCTCCGG AGTGGGCGGC CCTCGACTGG 
TCTGAGTGCA CCCCCAGCTG CGGGCCGGGC CTCCGCCACC GCGTGGTCCT TTGCAAGAGC 
GCAGACCACC GCGCCACGCT GCCCCCGGCG CACTGCTCAC CCGCCGCCAA GCCACCGGCC 
ACCATGCGCT GCAACTTGCG CCGCTGCCCC CCGGCCCGCT GGGTGGCTGG CGAGTGGGGT 
GAGTGCTCTG CACAGTGCGG CGTCGGGCAG CGGCAGCGCT CGGTGCGCTG CACCAGCCAC 
ACGGGCCAGG CGTCGCACGA GTGCACGGAG GCCCTGCGGC CGCCCACCAC GCAGCAGTGT 
GAGGCCAAGT GCGACAGCCC AACCCCCGGG GACGGCCCTG AAGAGTGCAA GGATGTGAAC 
AAGGTCGCCT ACTGCCCCCT GGTGCTCAAA TTTCAGTTCT GCAGCCGAGC CTACTTCCGC 
CAGATGTGCT GCAAAACCTG CCATGGCCAC TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ADAMTS10 ( XM_006722917.3 ) cDNA ORF clone, Homo sapiens(human) -> XP_006722980.1 Homo sapiens ADAM metallopeptidase with thrombospondin type 1 motif 10 (ADAMTS10), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu51850
Clone ID Related Accession (Same CDS sequence)	XM_006722917.3
Accession Version	XM_006722917.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2355bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	A disintegrin and metalloproteinase with thrombospondin motifs 10 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000019.10) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_006722917.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTGTGAGC GCGAGAGAAG CTGCAGCGTC AATGAGGACA TTGGCCTGGC CACAGCGTTC 
ACCATTGCCC ACGAGATCGG GCACACATTC GGCATGAACC ATGACGGCGT GGGAAACAGC 
TGTGGGGCCC GTGGTCAGGA CCCAGCCAAG CTCATGGCTG CCCACATTAC CATGAAGACC 
AACCCATTCG TGTGGTCATC CTGCAGCCGT GACTACATCA CCAGCTTTCT AGACTCGGGC 
CTGGGGCTCT GCCTGAACAA CCGGCCCCCC AGACAGGACT TTGTGTACCC GACAGTGGCA 
CCGGGCCAAG CCTACGATGC AGATGAGCAA TGCCGCTTTC AGCATGGAGT CAAATCGCGT 
CAGTGTAAAT ACGGGGAGGT CTGCAGCGAG CTGTGGTGTC TGAGCAAGAG CAACCGGTGC 
ATCACCAACA GCATCCCGGC CGCCGAGGGC ACGCTGTGCC AGACGCACAC CATCGACAAG 
GGGTGGTGCT ACAAACGGGT CTGTGTCCCC TTTGGGTCGC GCCCAGAGGG TGTGGACGGA 
GCCTGGGGGC CGTGGACTCC ATGGGGCGAC TGCAGCCGGA CCTGTGGCGG CGGCGTGTCC 
TCTTCTAGCC GTCACTGCGA CAGCCCCAGG CCAACCATCG GGGGCAAGTA CTGTCTGGGT 
GAGAGAAGGC GGCACCGCTC CTGCAACACG GATGACTGTC CCCCTGGCTC CCAGGACTTC 
AGAGAAGTGC AGTGTTCTGA ATTTGACAGC ATCCCTTTCC GTGGGAAATT CTACAAGTGG 
AAAACGTACC GGGGAGGGGG CGTGAAGGCC TGCTCGCTCA CGTGCCTAGC GGAAGGCTTC 
AACTTCTACA CGGAGAGGGC GGCAGCCGTG GTGGACGGGA CACCCTGCCG TCCAGACACG 
GTGGACATTT GCGTCAGTGG CGAATGCAAG CACGTGGGCT GCGACCGAGT CCTGGGCTCC 
GACCTGCGGG AGGACAAGTG CCGAGTGTGT GGCGGTGACG GCAGTGCCTG CGAGACCATC 
GAGGGCGTCT TCAGCCCAGC CTCACCTGGG GCCGGGTACG AGGATGTCGT CTGGATTCCC 
AAAGGCTCCG TCCACATCTT CATCCAGGAT CTGAACCTCT CTCTCAGTCA CTTGGCCCTG 
AAGGGAGACC AGGAGTCCCT GCTGCTGGAG GGGCTGCCTG GGACCCCCCA GCCCCACCGT 
CTGCCTCTAG CTGGGACCAC CTTTCAACTG CGACAGGGGC CAGACCAGGT CCAGAGCCTC 
GAAGCCCTGG GACCGATTAA TGCATCTCTC ATCGTCATGG TGCTGGCCCG GACCGAGCTG 
CCTGCCCTCC GCTACCGCTT CAATGCCCCC ATCGCCCGTG ACTCGCTGCC CCCCTACTCC 
TGGCACTATG CGCCCTGGAC CAAGTGCTCG GCCCAGTGTG CAGGCGGTAG CCAGGTGCAG 
GCGGTGGAGT GCCGCAACCA GCTGGACAGC TCCGCGGTCG CCCCCCACTA CTGCAGTGCC 
CACAGCAAGC TGCCCAAAAG GCAGCGCGCC TGCAACACGG AGCCTTGCCC TCCAGACTGG 
GTTGTAGGGA ACTGGTCGCT CTGCAGCCGC AGCTGCGATG CAGGCGTGCG CAGCCGCTCG 
GTCGTGTGCC AGCGCCGCGT CTCTGCCGCG GAGGAGAAGG CGCTGGACGA CAGCGCATGC 
CCGCAGCCGC GCCCACCTGT ACTGGAGGCC TGCCACGGCC CCACTTGCCC TCCGGAGTGG 
GCGGCCCTCG ACTGGTCTGA GGTCAGCCGC CCCCTTCCTT CGCGCCCACT GGGATGCCCA 
GGTGGGGTGT CCACGGAGAC GCCTCTGCGC GGTCTCCAGG TTAGCTGTCC CCTCCTCACT 
TCGCACTGGG GCAGCACCCT GAGCACGAAA CGCCCCTTCC AACTGCAGTG CACCCCCAGC 
TGCGGGCCGG GCCTCCGCCA CCGCGTGGTC CTTTGCAAGA GCGCAGACCA CCGCGCCACG 
CTGCCCCCGG CGCACTGCTC ACCCGCCGCC AAGCCACCGG CCACCATGCG CTGCAACTTG 
CGCCGCTGCC CCCCGGCCCG CTGGGTGGCT GGCGAGTGGG GTGAGTGCTC TGCACAGTGC 
GGCGTCGGGC AGCGGCAGCG CTCGGTGCGC TGCACCAGCC ACACGGGCCA GGCGTCGCAC 
GAGTGCACGG AGGCCCTGCG GCCGCCCACC ACGCAGCAGT GTGAGGCCAA GTGCGACAGC 
CCAACCCCCG GGGACGGCCC TGAAGAGTGC AAGGATGTGA ACAAGGTCGC CTACTGCCCC 
CTGGTGCTCA AATTTCAGTT CTGCAGCCGA GCCTACTTCC GCCAGATGTG CTGCAAAACC 
TGCCATGGCC ACTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006722980.1
CDS	1257..3611
Translation	MCERERSCSVNEDIGLATAFTIAHEIGHTFGMNHDGVGNSCGARGQDPAKLMAAHITMKTNPFVWSSCSRDYITSFLDSGLGLCLNNRPPRQDFVYPTVAPGQAYDADEQCRFQHGVKSRQCKYGEVCSELWCLSKSNRCITNSIPAAEGTLCQTHTIDKGWCYKRVCVPFGSRPEGVDGAWGPWTPWGDCSRTCGGGVSSSSRHCDSPRPTIGGKYCLGERRRHRSCNTDDCPPGSQDFREVQCSEFDSIPFRGKFYKWKTYRGGGVKACSLTCLAEGFNFYTERAAAVVDGTPCRPDTVDICVSGECKHVGCDRVLGSDLREDKCRVCGGDGSACETIEGVFSPASPGAGYEDVVWIPKGSVHIFIQDLNLSLSHLALKGDQESLLLEGLPGTPQPHRLPLAGTTFQLRQGPDQVQSLEALGPINASLIVMVLARTELPALRYRFNAPIARDSLPPYSWHYAPWTKCSAQCAGGSQVQAVECRNQLDSSAVAPHYCSAHSKLPKRQRACNTEPCPPDWVVGNWSLCSRSCDAGVRSRSVVCQRRVSAAEEKALDDSACPQPRPPVLEACHGPTCPPEWAALDWSEVSRPLPSRPLGCPGGVSTETPLRGLQVSCPLLTSHWGSTLSTKRPFQLQCTPSCGPGLRHRVVLCKSADHRATLPPAHCSPAAKPPATMRCNLRRCPPARWVAGEWGECSAQCGVGQRQRSVRCTSHTGQASHECTEALRPPTTQQCEAKCDSPTPGDGPEECKDVNKVAYCPLVLKFQFCSRAYFRQMCCKTCHGH

Target ORF information:

RefSeq Version	XM_006722917.3
Organism	Homo sapiens(human)
Definition	Homo sapiens ADAM metallopeptidase with thrombospondin type 1 motif 10 (ADAMTS10), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006722917.3

ORF Insert Sequence:

ATGTGTGAGC GCGAGAGAAG CTGCAGCGTC AATGAGGACA TTGGCCTGGC CACAGCGTTC 
ACCATTGCCC ACGAGATCGG GCACACATTC GGCATGAACC ATGACGGCGT GGGAAACAGC 
TGTGGGGCCC GTGGTCAGGA CCCAGCCAAG CTCATGGCTG CCCACATTAC CATGAAGACC 
AACCCATTCG TGTGGTCATC CTGCAGCCGT GACTACATCA CCAGCTTTCT AGACTCGGGC 
CTGGGGCTCT GCCTGAACAA CCGGCCCCCC AGACAGGACT TTGTGTACCC GACAGTGGCA 
CCGGGCCAAG CCTACGATGC AGATGAGCAA TGCCGCTTTC AGCATGGAGT CAAATCGCGT 
CAGTGTAAAT ACGGGGAGGT CTGCAGCGAG CTGTGGTGTC TGAGCAAGAG CAACCGGTGC 
ATCACCAACA GCATCCCGGC CGCCGAGGGC ACGCTGTGCC AGACGCACAC CATCGACAAG 
GGGTGGTGCT ACAAACGGGT CTGTGTCCCC TTTGGGTCGC GCCCAGAGGG TGTGGACGGA 
GCCTGGGGGC CGTGGACTCC ATGGGGCGAC TGCAGCCGGA CCTGTGGCGG CGGCGTGTCC 
TCTTCTAGCC GTCACTGCGA CAGCCCCAGG CCAACCATCG GGGGCAAGTA CTGTCTGGGT 
GAGAGAAGGC GGCACCGCTC CTGCAACACG GATGACTGTC CCCCTGGCTC CCAGGACTTC 
AGAGAAGTGC AGTGTTCTGA ATTTGACAGC ATCCCTTTCC GTGGGAAATT CTACAAGTGG 
AAAACGTACC GGGGAGGGGG CGTGAAGGCC TGCTCGCTCA CGTGCCTAGC GGAAGGCTTC 
AACTTCTACA CGGAGAGGGC GGCAGCCGTG GTGGACGGGA CACCCTGCCG TCCAGACACG 
GTGGACATTT GCGTCAGTGG CGAATGCAAG CACGTGGGCT GCGACCGAGT CCTGGGCTCC 
GACCTGCGGG AGGACAAGTG CCGAGTGTGT GGCGGTGACG GCAGTGCCTG CGAGACCATC 
GAGGGCGTCT TCAGCCCAGC CTCACCTGGG GCCGGGTACG AGGATGTCGT CTGGATTCCC 
AAAGGCTCCG TCCACATCTT CATCCAGGAT CTGAACCTCT CTCTCAGTCA CTTGGCCCTG 
AAGGGAGACC AGGAGTCCCT GCTGCTGGAG GGGCTGCCTG GGACCCCCCA GCCCCACCGT 
CTGCCTCTAG CTGGGACCAC CTTTCAACTG CGACAGGGGC CAGACCAGGT CCAGAGCCTC 
GAAGCCCTGG GACCGATTAA TGCATCTCTC ATCGTCATGG TGCTGGCCCG GACCGAGCTG 
CCTGCCCTCC GCTACCGCTT CAATGCCCCC ATCGCCCGTG ACTCGCTGCC CCCCTACTCC 
TGGCACTATG CGCCCTGGAC CAAGTGCTCG GCCCAGTGTG CAGGCGGTAG CCAGGTGCAG 
GCGGTGGAGT GCCGCAACCA GCTGGACAGC TCCGCGGTCG CCCCCCACTA CTGCAGTGCC 
CACAGCAAGC TGCCCAAAAG GCAGCGCGCC TGCAACACGG AGCCTTGCCC TCCAGACTGG 
GTTGTAGGGA ACTGGTCGCT CTGCAGCCGC AGCTGCGATG CAGGCGTGCG CAGCCGCTCG 
GTCGTGTGCC AGCGCCGCGT CTCTGCCGCG GAGGAGAAGG CGCTGGACGA CAGCGCATGC 
CCGCAGCCGC GCCCACCTGT ACTGGAGGCC TGCCACGGCC CCACTTGCCC TCCGGAGTGG 
GCGGCCCTCG ACTGGTCTGA GGTCAGCCGC CCCCTTCCTT CGCGCCCACT GGGATGCCCA 
GGTGGGGTGT CCACGGAGAC GCCTCTGCGC GGTCTCCAGG TTAGCTGTCC CCTCCTCACT 
TCGCACTGGG GCAGCACCCT GAGCACGAAA CGCCCCTTCC AACTGCAGTG CACCCCCAGC 
TGCGGGCCGG GCCTCCGCCA CCGCGTGGTC CTTTGCAAGA GCGCAGACCA CCGCGCCACG 
CTGCCCCCGG CGCACTGCTC ACCCGCCGCC AAGCCACCGG CCACCATGCG CTGCAACTTG 
CGCCGCTGCC CCCCGGCCCG CTGGGTGGCT GGCGAGTGGG GTGAGTGCTC TGCACAGTGC 
GGCGTCGGGC AGCGGCAGCG CTCGGTGCGC TGCACCAGCC ACACGGGCCA GGCGTCGCAC 
GAGTGCACGG AGGCCCTGCG GCCGCCCACC ACGCAGCAGT GTGAGGCCAA GTGCGACAGC 
CCAACCCCCG GGGACGGCCC TGAAGAGTGC AAGGATGTGA ACAAGGTCGC CTACTGCCCC 
CTGGTGCTCA AATTTCAGTT CTGCAGCCGA GCCTACTTCC GCCAGATGTG CTGCAAAACC 
TGCCATGGCC ACTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ADAMTS10 ( XM_017027339.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016882828.1 Homo sapiens ADAM metallopeptidase with thrombospondin type 1 motif 10 (ADAMTS10), transcript variant X4, mRNA.

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CloneID	OHu88745
Clone ID Related Accession (Same CDS sequence)	XM_017027339.1
Accession Version	XM_017027339.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1881bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	A disintegrin and metalloproteinase with thrombospondin motifs 10 isoform X3
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000019.10) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCAGATGA GCAATGCCGC TTTCAGCATG GAGTCAAATC GCGTCAGTGA GGTCTGCAGC 
GAGCTGTGGT GTCTGAGCAA GAGCAACCGG TGCATCACCA ACAGCATCCC GGCCGCCGAG 
GGCACGCTGT GCCAGACGCA CACCATCGAC AAGGGGTGGT GCTACAAACG GGTCTGTGTC 
CCCTTTGGGT CGCGCCCAGA GGGTGTGGAC GGAGCCTGGG GGCCGTGGAC TCCATGGGGC 
GACTGCAGCC GGACCTGTGG CGGCGGCGTG TCCTCTTCTA GCCGTCACTG CGACAGCCCC 
AGGCCAACCA TCGGGGGCAA GTACTGTCTG GGTGAGAGAA GGCGGCACCG CTCCTGCAAC 
ACGGATGACT GTCCCCCTGG CTCCCAGGAC TTCAGAGAAG TGCAGTGTTC TGAATTTGAC 
AGCATCCCTT TCCGTGGGAA ATTCTACAAG TGGAAAACGT ACCGGGGAGG GGGCGTGAAG 
GCCTGCTCGC TCACGTGCCT AGCGGAAGGC TTCAACTTCT ACACGGAGAG GGCGGCAGCC 
GTGGTGGACG GGACACCCTG CCGTCCAGAC ACGGTGGACA TTTGCGTCAG TGGCGAATGC 
AAGCACGTGG GCTGCGACCG AGTCCTGGGC TCCGACCTGC GGGAGGACAA GTGCCGAGTG 
TGTGGCGGTG ACGGCAGTGC CTGCGAGACC ATCGAGGGCG TCTTCAGCCC AGCCTCACCT 
GGGGCCGGGT ACGAGGATGT CGTCTGGATT CCCAAAGGCT CCGTCCACAT CTTCATCCAG 
GATCTGAACC TCTCTCTCAG TCACTTGGCC CTGAAGGGAG ACCAGGAGTC CCTGCTGCTG 
GAGGGGCTGC CTGGGACCCC CCAGCCCCAC CGTCTGCCTC TAGCTGGGAC CACCTTTCAA 
CTGCGACAGG GGCCAGACCA GGTCCAGAGC CTCGAAGCCC TGGGACCGAT TAATGCATCT 
CTCATCGTCA TGGTGCTGGC CCGGACCGAG CTGCCTGCCC TCCGCTACCG CTTCAATGCC 
CCCATCGCCC GTGACTCGCT GCCCCCCTAC TCCTGGCACT ATGCGCCCTG GACCAAGTGC 
TCGGCCCAGT GTGCAGGCGG TAGCCAGGTG CAGGCGGTGG AGTGCCGCAA CCAGCTGGAC 
AGCTCCGCGG TCGCCCCCCA CTACTGCAGT GCCCACAGCA AGCTGCCCAA AAGGCAGCGC 
GCCTGCAACA CGGAGCCTTG CCCTCCAGAC TGGGTTGTAG GGAACTGGTC GCTCTGCAGC 
CGCAGCTGCG ATGCAGGCGT GCGCAGCCGC TCGGTCGTGT GCCAGCGCCG CGTCTCTGCC 
GCGGAGGAGA AGGCGCTGGA CGACAGCGCA TGCCCGCAGC CGCGCCCACC TGTACTGGAG 
GCCTGCCACG GCCCCACTTG CCCTCCGGAG TGGGCGGCCC TCGACTGGTC TGAGTGCACC 
CCCAGCTGCG GGCCGGGCCT CCGCCACCGC GTGGTCCTTT GCAAGAGCGC AGACCACCGC 
GCCACGCTGC CCCCGGCGCA CTGCTCACCC GCCGCCAAGC CACCGGCCAC CATGCGCTGC 
AACTTGCGCC GCTGCCCCCC GGCCCGCTGG GTGGCTGGCG AGTGGGGTGA GTGCTCTGCA 
CAGTGCGGCG TCGGGCAGCG GCAGCGCTCG GTGCGCTGCA CCAGCCACAC GGGCCAGGCG 
TCGCACGAGT GCACGGAGGC CCTGCGGCCG CCCACCACGC AGCAGTGTGA GGCCAAGTGC 
GACAGCCCAA CCCCCGGGGA CGGCCCTGAA GAGTGCAAGG ATGTGAACAA GGTCGCCTAC 
TGCCCCCTGG TGCTCAAATT TCAGTTCTGC AGCCGAGCCT ACTTCCGCCA GATGTGCTGC 
AAAACCTGCC ATGGCCACTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016882828.1
CDS	218..2098
Translation	MQMSNAAFSMESNRVSEVCSELWCLSKSNRCITNSIPAAEGTLCQTHTIDKGWCYKRVCVPFGSRPEGVDGAWGPWTPWGDCSRTCGGGVSSSSRHCDSPRPTIGGKYCLGERRRHRSCNTDDCPPGSQDFREVQCSEFDSIPFRGKFYKWKTYRGGGVKACSLTCLAEGFNFYTERAAAVVDGTPCRPDTVDICVSGECKHVGCDRVLGSDLREDKCRVCGGDGSACETIEGVFSPASPGAGYEDVVWIPKGSVHIFIQDLNLSLSHLALKGDQESLLLEGLPGTPQPHRLPLAGTTFQLRQGPDQVQSLEALGPINASLIVMVLARTELPALRYRFNAPIARDSLPPYSWHYAPWTKCSAQCAGGSQVQAVECRNQLDSSAVAPHYCSAHSKLPKRQRACNTEPCPPDWVVGNWSLCSRSCDAGVRSRSVVCQRRVSAAEEKALDDSACPQPRPPVLEACHGPTCPPEWAALDWSECTPSCGPGLRHRVVLCKSADHRATLPPAHCSPAAKPPATMRCNLRRCPPARWVAGEWGECSAQCGVGQRQRSVRCTSHTGQASHECTEALRPPTTQQCEAKCDSPTPGDGPEECKDVNKVAYCPLVLKFQFCSRAYFRQMCCKTCHGH

Target ORF information:

RefSeq Version	XM_017027339.1
Organism	Homo sapiens(human)
Definition	Homo sapiens ADAM metallopeptidase with thrombospondin type 1 motif 10 (ADAMTS10), transcript variant X4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017027339.1

ORF Insert Sequence:

ATGCAGATGA GCAATGCCGC TTTCAGCATG GAGTCAAATC GCGTCAGTGA GGTCTGCAGC 
GAGCTGTGGT GTCTGAGCAA GAGCAACCGG TGCATCACCA ACAGCATCCC GGCCGCCGAG 
GGCACGCTGT GCCAGACGCA CACCATCGAC AAGGGGTGGT GCTACAAACG GGTCTGTGTC 
CCCTTTGGGT CGCGCCCAGA GGGTGTGGAC GGAGCCTGGG GGCCGTGGAC TCCATGGGGC 
GACTGCAGCC GGACCTGTGG CGGCGGCGTG TCCTCTTCTA GCCGTCACTG CGACAGCCCC 
AGGCCAACCA TCGGGGGCAA GTACTGTCTG GGTGAGAGAA GGCGGCACCG CTCCTGCAAC 
ACGGATGACT GTCCCCCTGG CTCCCAGGAC TTCAGAGAAG TGCAGTGTTC TGAATTTGAC 
AGCATCCCTT TCCGTGGGAA ATTCTACAAG TGGAAAACGT ACCGGGGAGG GGGCGTGAAG 
GCCTGCTCGC TCACGTGCCT AGCGGAAGGC TTCAACTTCT ACACGGAGAG GGCGGCAGCC 
GTGGTGGACG GGACACCCTG CCGTCCAGAC ACGGTGGACA TTTGCGTCAG TGGCGAATGC 
AAGCACGTGG GCTGCGACCG AGTCCTGGGC TCCGACCTGC GGGAGGACAA GTGCCGAGTG 
TGTGGCGGTG ACGGCAGTGC CTGCGAGACC ATCGAGGGCG TCTTCAGCCC AGCCTCACCT 
GGGGCCGGGT ACGAGGATGT CGTCTGGATT CCCAAAGGCT CCGTCCACAT CTTCATCCAG 
GATCTGAACC TCTCTCTCAG TCACTTGGCC CTGAAGGGAG ACCAGGAGTC CCTGCTGCTG 
GAGGGGCTGC CTGGGACCCC CCAGCCCCAC CGTCTGCCTC TAGCTGGGAC CACCTTTCAA 
CTGCGACAGG GGCCAGACCA GGTCCAGAGC CTCGAAGCCC TGGGACCGAT TAATGCATCT 
CTCATCGTCA TGGTGCTGGC CCGGACCGAG CTGCCTGCCC TCCGCTACCG CTTCAATGCC 
CCCATCGCCC GTGACTCGCT GCCCCCCTAC TCCTGGCACT ATGCGCCCTG GACCAAGTGC 
TCGGCCCAGT GTGCAGGCGG TAGCCAGGTG CAGGCGGTGG AGTGCCGCAA CCAGCTGGAC 
AGCTCCGCGG TCGCCCCCCA CTACTGCAGT GCCCACAGCA AGCTGCCCAA AAGGCAGCGC 
GCCTGCAACA CGGAGCCTTG CCCTCCAGAC TGGGTTGTAG GGAACTGGTC GCTCTGCAGC 
CGCAGCTGCG ATGCAGGCGT GCGCAGCCGC TCGGTCGTGT GCCAGCGCCG CGTCTCTGCC 
GCGGAGGAGA AGGCGCTGGA CGACAGCGCA TGCCCGCAGC CGCGCCCACC TGTACTGGAG 
GCCTGCCACG GCCCCACTTG CCCTCCGGAG TGGGCGGCCC TCGACTGGTC TGAGTGCACC 
CCCAGCTGCG GGCCGGGCCT CCGCCACCGC GTGGTCCTTT GCAAGAGCGC AGACCACCGC 
GCCACGCTGC CCCCGGCGCA CTGCTCACCC GCCGCCAAGC CACCGGCCAC CATGCGCTGC 
AACTTGCGCC GCTGCCCCCC GGCCCGCTGG GTGGCTGGCG AGTGGGGTGA GTGCTCTGCA 
CAGTGCGGCG TCGGGCAGCG GCAGCGCTCG GTGCGCTGCA CCAGCCACAC GGGCCAGGCG 
TCGCACGAGT GCACGGAGGC CCTGCGGCCG CCCACCACGC AGCAGTGTGA GGCCAAGTGC 
GACAGCCCAA CCCCCGGGGA CGGCCCTGAA GAGTGCAAGG ATGTGAACAA GGTCGCCTAC 
TGCCCCCTGG TGCTCAAATT TCAGTTCTGC AGCCGAGCCT ACTTCCGCCA GATGTGCTGC 
AAAACCTGCC ATGGCCACTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ADAMTS10 ( XM_017027340.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016882829.1 Homo sapiens ADAM metallopeptidase with thrombospondin type 1 motif 10 (ADAMTS10), transcript variant X5, mRNA.

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CloneID	OHu88746
Clone ID Related Accession (Same CDS sequence)	XM_017027340.1
Accession Version	XM_017027340.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1875bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	A disintegrin and metalloproteinase with thrombospondin motifs 10 isoform X4
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000019.10) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCAGATGA GCAATGCCGC TTTCAGCATG GAGTCAAATC GCGAGGTCTG CAGCGAGCTG 
TGGTGTCTGA GCAAGAGCAA CCGGTGCATC ACCAACAGCA TCCCGGCCGC CGAGGGCACG 
CTGTGCCAGA CGCACACCAT CGACAAGGGG TGGTGCTACA AACGGGTCTG TGTCCCCTTT 
GGGTCGCGCC CAGAGGGTGT GGACGGAGCC TGGGGGCCGT GGACTCCATG GGGCGACTGC 
AGCCGGACCT GTGGCGGCGG CGTGTCCTCT TCTAGCCGTC ACTGCGACAG CCCCAGGCCA 
ACCATCGGGG GCAAGTACTG TCTGGGTGAG AGAAGGCGGC ACCGCTCCTG CAACACGGAT 
GACTGTCCCC CTGGCTCCCA GGACTTCAGA GAAGTGCAGT GTTCTGAATT TGACAGCATC 
CCTTTCCGTG GGAAATTCTA CAAGTGGAAA ACGTACCGGG GAGGGGGCGT GAAGGCCTGC 
TCGCTCACGT GCCTAGCGGA AGGCTTCAAC TTCTACACGG AGAGGGCGGC AGCCGTGGTG 
GACGGGACAC CCTGCCGTCC AGACACGGTG GACATTTGCG TCAGTGGCGA ATGCAAGCAC 
GTGGGCTGCG ACCGAGTCCT GGGCTCCGAC CTGCGGGAGG ACAAGTGCCG AGTGTGTGGC 
GGTGACGGCA GTGCCTGCGA GACCATCGAG GGCGTCTTCA GCCCAGCCTC ACCTGGGGCC 
GGGTACGAGG ATGTCGTCTG GATTCCCAAA GGCTCCGTCC ACATCTTCAT CCAGGATCTG 
AACCTCTCTC TCAGTCACTT GGCCCTGAAG GGAGACCAGG AGTCCCTGCT GCTGGAGGGG 
CTGCCTGGGA CCCCCCAGCC CCACCGTCTG CCTCTAGCTG GGACCACCTT TCAACTGCGA 
CAGGGGCCAG ACCAGGTCCA GAGCCTCGAA GCCCTGGGAC CGATTAATGC ATCTCTCATC 
GTCATGGTGC TGGCCCGGAC CGAGCTGCCT GCCCTCCGCT ACCGCTTCAA TGCCCCCATC 
GCCCGTGACT CGCTGCCCCC CTACTCCTGG CACTATGCGC CCTGGACCAA GTGCTCGGCC 
CAGTGTGCAG GCGGTAGCCA GGTGCAGGCG GTGGAGTGCC GCAACCAGCT GGACAGCTCC 
GCGGTCGCCC CCCACTACTG CAGTGCCCAC AGCAAGCTGC CCAAAAGGCA GCGCGCCTGC 
AACACGGAGC CTTGCCCTCC AGACTGGGTT GTAGGGAACT GGTCGCTCTG CAGCCGCAGC 
TGCGATGCAG GCGTGCGCAG CCGCTCGGTC GTGTGCCAGC GCCGCGTCTC TGCCGCGGAG 
GAGAAGGCGC TGGACGACAG CGCATGCCCG CAGCCGCGCC CACCTGTACT GGAGGCCTGC 
CACGGCCCCA CTTGCCCTCC GGAGTGGGCG GCCCTCGACT GGTCTGAGTG CACCCCCAGC 
TGCGGGCCGG GCCTCCGCCA CCGCGTGGTC CTTTGCAAGA GCGCAGACCA CCGCGCCACG 
CTGCCCCCGG CGCACTGCTC ACCCGCCGCC AAGCCACCGG CCACCATGCG CTGCAACTTG 
CGCCGCTGCC CCCCGGCCCG CTGGGTGGCT GGCGAGTGGG GTGAGTGCTC TGCACAGTGC 
GGCGTCGGGC AGCGGCAGCG CTCGGTGCGC TGCACCAGCC ACACGGGCCA GGCGTCGCAC 
GAGTGCACGG AGGCCCTGCG GCCGCCCACC ACGCAGCAGT GTGAGGCCAA GTGCGACAGC 
CCAACCCCCG GGGACGGCCC TGAAGAGTGC AAGGATGTGA ACAAGGTCGC CTACTGCCCC 
CTGGTGCTCA AATTTCAGTT CTGCAGCCGA GCCTACTTCC GCCAGATGTG CTGCAAAACC 
TGCCATGGCC ACTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016882829.1
CDS	84..1958
Translation	MQMSNAAFSMESNREVCSELWCLSKSNRCITNSIPAAEGTLCQTHTIDKGWCYKRVCVPFGSRPEGVDGAWGPWTPWGDCSRTCGGGVSSSSRHCDSPRPTIGGKYCLGERRRHRSCNTDDCPPGSQDFREVQCSEFDSIPFRGKFYKWKTYRGGGVKACSLTCLAEGFNFYTERAAAVVDGTPCRPDTVDICVSGECKHVGCDRVLGSDLREDKCRVCGGDGSACETIEGVFSPASPGAGYEDVVWIPKGSVHIFIQDLNLSLSHLALKGDQESLLLEGLPGTPQPHRLPLAGTTFQLRQGPDQVQSLEALGPINASLIVMVLARTELPALRYRFNAPIARDSLPPYSWHYAPWTKCSAQCAGGSQVQAVECRNQLDSSAVAPHYCSAHSKLPKRQRACNTEPCPPDWVVGNWSLCSRSCDAGVRSRSVVCQRRVSAAEEKALDDSACPQPRPPVLEACHGPTCPPEWAALDWSECTPSCGPGLRHRVVLCKSADHRATLPPAHCSPAAKPPATMRCNLRRCPPARWVAGEWGECSAQCGVGQRQRSVRCTSHTGQASHECTEALRPPTTQQCEAKCDSPTPGDGPEECKDVNKVAYCPLVLKFQFCSRAYFRQMCCKTCHGH

Target ORF information:

RefSeq Version	XM_017027340.1
Organism	Homo sapiens(human)
Definition	Homo sapiens ADAM metallopeptidase with thrombospondin type 1 motif 10 (ADAMTS10), transcript variant X5, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017027340.1

ORF Insert Sequence:

ATGCAGATGA GCAATGCCGC TTTCAGCATG GAGTCAAATC GCGAGGTCTG CAGCGAGCTG 
TGGTGTCTGA GCAAGAGCAA CCGGTGCATC ACCAACAGCA TCCCGGCCGC CGAGGGCACG 
CTGTGCCAGA CGCACACCAT CGACAAGGGG TGGTGCTACA AACGGGTCTG TGTCCCCTTT 
GGGTCGCGCC CAGAGGGTGT GGACGGAGCC TGGGGGCCGT GGACTCCATG GGGCGACTGC 
AGCCGGACCT GTGGCGGCGG CGTGTCCTCT TCTAGCCGTC ACTGCGACAG CCCCAGGCCA 
ACCATCGGGG GCAAGTACTG TCTGGGTGAG AGAAGGCGGC ACCGCTCCTG CAACACGGAT 
GACTGTCCCC CTGGCTCCCA GGACTTCAGA GAAGTGCAGT GTTCTGAATT TGACAGCATC 
CCTTTCCGTG GGAAATTCTA CAAGTGGAAA ACGTACCGGG GAGGGGGCGT GAAGGCCTGC 
TCGCTCACGT GCCTAGCGGA AGGCTTCAAC TTCTACACGG AGAGGGCGGC AGCCGTGGTG 
GACGGGACAC CCTGCCGTCC AGACACGGTG GACATTTGCG TCAGTGGCGA ATGCAAGCAC 
GTGGGCTGCG ACCGAGTCCT GGGCTCCGAC CTGCGGGAGG ACAAGTGCCG AGTGTGTGGC 
GGTGACGGCA GTGCCTGCGA GACCATCGAG GGCGTCTTCA GCCCAGCCTC ACCTGGGGCC 
GGGTACGAGG ATGTCGTCTG GATTCCCAAA GGCTCCGTCC ACATCTTCAT CCAGGATCTG 
AACCTCTCTC TCAGTCACTT GGCCCTGAAG GGAGACCAGG AGTCCCTGCT GCTGGAGGGG 
CTGCCTGGGA CCCCCCAGCC CCACCGTCTG CCTCTAGCTG GGACCACCTT TCAACTGCGA 
CAGGGGCCAG ACCAGGTCCA GAGCCTCGAA GCCCTGGGAC CGATTAATGC ATCTCTCATC 
GTCATGGTGC TGGCCCGGAC CGAGCTGCCT GCCCTCCGCT ACCGCTTCAA TGCCCCCATC 
GCCCGTGACT CGCTGCCCCC CTACTCCTGG CACTATGCGC CCTGGACCAA GTGCTCGGCC 
CAGTGTGCAG GCGGTAGCCA GGTGCAGGCG GTGGAGTGCC GCAACCAGCT GGACAGCTCC 
GCGGTCGCCC CCCACTACTG CAGTGCCCAC AGCAAGCTGC CCAAAAGGCA GCGCGCCTGC 
AACACGGAGC CTTGCCCTCC AGACTGGGTT GTAGGGAACT GGTCGCTCTG CAGCCGCAGC 
TGCGATGCAG GCGTGCGCAG CCGCTCGGTC GTGTGCCAGC GCCGCGTCTC TGCCGCGGAG 
GAGAAGGCGC TGGACGACAG CGCATGCCCG CAGCCGCGCC CACCTGTACT GGAGGCCTGC 
CACGGCCCCA CTTGCCCTCC GGAGTGGGCG GCCCTCGACT GGTCTGAGTG CACCCCCAGC 
TGCGGGCCGG GCCTCCGCCA CCGCGTGGTC CTTTGCAAGA GCGCAGACCA CCGCGCCACG 
CTGCCCCCGG CGCACTGCTC ACCCGCCGCC AAGCCACCGG CCACCATGCG CTGCAACTTG 
CGCCGCTGCC CCCCGGCCCG CTGGGTGGCT GGCGAGTGGG GTGAGTGCTC TGCACAGTGC 
GGCGTCGGGC AGCGGCAGCG CTCGGTGCGC TGCACCAGCC ACACGGGCCA GGCGTCGCAC 
GAGTGCACGG AGGCCCTGCG GCCGCCCACC ACGCAGCAGT GTGAGGCCAA GTGCGACAGC 
CCAACCCCCG GGGACGGCCC TGAAGAGTGC AAGGATGTGA ACAAGGTCGC CTACTGCCCC 
CTGGTGCTCA AATTTCAGTT CTGCAGCCGA GCCTACTTCC GCCAGATGTG CTGCAAAACC 
TGCCATGGCC ACTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ADAMTS10 ( NM_030957.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_112219.3 Homo sapiens ADAM metallopeptidase with thrombospondin type 1 motif 10 (ADAMTS10), transcript variant 1, mRNA.

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CloneID	OHu20510
Clone ID Related Accession (Same CDS sequence)	NM_030957.4 , XM_017027338.1 , XM_017027338.2 , NM_030957.3
Accession Version	NM_030957.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3312bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-30
Organism	Homo sapiens(human)
Product	A disintegrin and metalloproteinase with thrombospondin motifs 10 isoform 1 preproprotein
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from CN431169.1, AB209515.1, AF163762.1, BC029308.1, AC130469.2, AK131414.1 and BF510205.1. This sequence is a reference standard in the RefSeqGene project. On Nov 22, 2018 this sequence version replaced NM_030957.3. Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## inferred exon combination :: based on alignments, homology MANE Ensembl match :: ENST00000597188.6/ ENSP00000471851.1 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGCTCCCG CCTGCCAGAT CCTCCGCTGG GCCCTCGCCC TGGGGCTGGG CCTCATGTTC 
GAGGTCACGC ACGCCTTCCG GTCTCAAGAT GAGTTCCTGT CCAGTCTGGA GAGCTATGAG 
ATCGCCTTCC CCACCCGCGT GGACCACAAC GGGGCACTGC TGGCCTTCTC GCCACCTCCT 
CCCCGGAGGC AGCGCCGCGG CACGGGGGCC ACAGCCGAGT CCCGCCTCTT CTACAAAGTG 
GCCTCGCCCA GCACCCACTT CCTGCTGAAC CTGACCCGCA GCTCCCGTCT ACTGGCAGGG 
CACGTCTCCG TGGAGTACTG GACACGGGAG GGCCTGGCCT GGCAGAGGGC GGCCCGGCCC 
CACTGCCTCT ACGCTGGTCA CCTGCAGGGC CAGGCCAGCA GCTCCCATGT GGCCATCAGC 
ACCTGTGGAG GCCTGCACGG CCTGATCGTG GCAGACGAGG AAGAGTACCT GATTGAGCCC 
CTGCACGGTG GGCCCAAGGG TTCTCGGAGC CCGGAGGAAA GTGGACCACA TGTGGTGTAC 
AAGCGTTCCT CTCTGCGTCA CCCCCACCTG GACACAGCCT GTGGAGTGAG AGATGAGAAA 
CCGTGGAAAG GGCGGCCATG GTGGCTGCGG ACCTTGAAGC CACCGCCTGC CAGGCCCCTG 
GGGAATGAAA CAGAGCGTGG CCAGCCAGGC CTGAAGCGAT CGGTCAGCCG AGAGCGCTAC 
GTGGAGACCC TGGTGGTGGC TGACAAGATG ATGGTGGCCT ATCACGGGCG CCGGGATGTG 
GAGCAGTATG TCCTGGCCAT CATGAACATT GTTGCCAAAC TTTTCCAGGA CTCGAGTCTG 
GGAAGCACCG TTAACATCCT CGTAACTCGC CTCATCCTGC TCACGGAGGA CCAGCCCACT 
CTGGAGATCA CCCACCATGC CGGGAAGTCC CTGGACAGCT TCTGTAAGTG GCAGAAATCC 
ATCGTGAACC ACAGCGGCCA TGGCAATGCC ATTCCAGAGA ACGGTGTGGC TAACCATGAC 
ACAGCAGTGC TCATCACACG CTATGACATC TGCATCTACA AGAACAAACC CTGCGGCACA 
CTAGGCCTGG CCCCGGTGGG CGGAATGTGT GAGCGCGAGA GAAGCTGCAG CGTCAATGAG 
GACATTGGCC TGGCCACAGC GTTCACCATT GCCCACGAGA TCGGGCACAC ATTCGGCATG 
AACCATGACG GCGTGGGAAA CAGCTGTGGG GCCCGTGGTC AGGACCCAGC CAAGCTCATG 
GCTGCCCACA TTACCATGAA GACCAACCCA TTCGTGTGGT CATCCTGCAG CCGTGACTAC 
ATCACCAGCT TTCTAGACTC GGGCCTGGGG CTCTGCCTGA ACAACCGGCC CCCCAGACAG 
GACTTTGTGT ACCCGACAGT GGCACCGGGC CAAGCCTACG ATGCAGATGA GCAATGCCGC 
TTTCAGCATG GAGTCAAATC GCGTCAGTGT AAATACGGGG AGGTCTGCAG CGAGCTGTGG 
TGTCTGAGCA AGAGCAACCG GTGCATCACC AACAGCATCC CGGCCGCCGA GGGCACGCTG 
TGCCAGACGC ACACCATCGA CAAGGGGTGG TGCTACAAAC GGGTCTGTGT CCCCTTTGGG 
TCGCGCCCAG AGGGTGTGGA CGGAGCCTGG GGGCCGTGGA CTCCATGGGG CGACTGCAGC 
CGGACCTGTG GCGGCGGCGT GTCCTCTTCT AGCCGTCACT GCGACAGCCC CAGGCCAACC 
ATCGGGGGCA AGTACTGTCT GGGTGAGAGA AGGCGGCACC GCTCCTGCAA CACGGATGAC 
TGTCCCCCTG GCTCCCAGGA CTTCAGAGAA GTGCAGTGTT CTGAATTTGA CAGCATCCCT 
TTCCGTGGGA AATTCTACAA GTGGAAAACG TACCGGGGAG GGGGCGTGAA GGCCTGCTCG 
CTCACGTGCC TAGCGGAAGG CTTCAACTTC TACACGGAGA GGGCGGCAGC CGTGGTGGAC 
GGGACACCCT GCCGTCCAGA CACGGTGGAC ATTTGCGTCA GTGGCGAATG CAAGCACGTG 
GGCTGCGACC GAGTCCTGGG CTCCGACCTG CGGGAGGACA AGTGCCGAGT GTGTGGCGGT 
GACGGCAGTG CCTGCGAGAC CATCGAGGGC GTCTTCAGCC CAGCCTCACC TGGGGCCGGG 
TACGAGGATG TCGTCTGGAT TCCCAAAGGC TCCGTCCACA TCTTCATCCA GGATCTGAAC 
CTCTCTCTCA GTCACTTGGC CCTGAAGGGA GACCAGGAGT CCCTGCTGCT GGAGGGGCTG 
CCTGGGACCC CCCAGCCCCA CCGTCTGCCT CTAGCTGGGA CCACCTTTCA ACTGCGACAG 
GGGCCAGACC AGGTCCAGAG CCTCGAAGCC CTGGGACCGA TTAATGCATC TCTCATCGTC 
ATGGTGCTGG CCCGGACCGA GCTGCCTGCC CTCCGCTACC GCTTCAATGC CCCCATCGCC 
CGTGACTCGC TGCCCCCCTA CTCCTGGCAC TATGCGCCCT GGACCAAGTG CTCGGCCCAG 
TGTGCAGGCG GTAGCCAGGT GCAGGCGGTG GAGTGCCGCA ACCAGCTGGA CAGCTCCGCG 
GTCGCCCCCC ACTACTGCAG TGCCCACAGC AAGCTGCCCA AAAGGCAGCG CGCCTGCAAC 
ACGGAGCCTT GCCCTCCAGA CTGGGTTGTA GGGAACTGGT CGCTCTGCAG CCGCAGCTGC 
GATGCAGGCG TGCGCAGCCG CTCGGTCGTG TGCCAGCGCC GCGTCTCTGC CGCGGAGGAG 
AAGGCGCTGG ACGACAGCGC ATGCCCGCAG CCGCGCCCAC CTGTACTGGA GGCCTGCCAC 
GGCCCCACTT GCCCTCCGGA GTGGGCGGCC CTCGACTGGT CTGAGTGCAC CCCCAGCTGC 
GGGCCGGGCC TCCGCCACCG CGTGGTCCTT TGCAAGAGCG CAGACCACCG CGCCACGCTG 
CCCCCGGCGC ACTGCTCACC CGCCGCCAAG CCACCGGCCA CCATGCGCTG CAACTTGCGC 
CGCTGCCCCC CGGCCCGCTG GGTGGCTGGC GAGTGGGGTG AGTGCTCTGC ACAGTGCGGC 
GTCGGGCAGC GGCAGCGCTC GGTGCGCTGC ACCAGCCACA CGGGCCAGGC GTCGCACGAG 
TGCACGGAGG CCCTGCGGCC GCCCACCACG CAGCAGTGTG AGGCCAAGTG CGACAGCCCA 
ACCCCCGGGG ACGGCCCTGA AGAGTGCAAG GATGTGAACA AGGTCGCCTA CTGCCCCCTG 
GTGCTCAAAT TTCAGTTCTG CAGCCGAGCC TACTTCCGCC AGATGTGCTG CAAAACCTGC 
CATGGCCACT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_112219.3
CDS	287..3598
Translation	MAPACQILRWALALGLGLMFEVTHAFRSQDEFLSSLESYEIAFPTRVDHNGALLAFSPPPPRRQRRGTGATAESRLFYKVASPSTHFLLNLTRSSRLLAGHVSVEYWTREGLAWQRAARPHCLYAGHLQGQASSSHVAISTCGGLHGLIVADEEEYLIEPLHGGPKGSRSPEESGPHVVYKRSSLRHPHLDTACGVRDEKPWKGRPWWLRTLKPPPARPLGNETERGQPGLKRSVSRERYVETLVVADKMMVAYHGRRDVEQYVLAIMNIVAKLFQDSSLGSTVNILVTRLILLTEDQPTLEITHHAGKSLDSFCKWQKSIVNHSGHGNAIPENGVANHDTAVLITRYDICIYKNKPCGTLGLAPVGGMCERERSCSVNEDIGLATAFTIAHEIGHTFGMNHDGVGNSCGARGQDPAKLMAAHITMKTNPFVWSSCSRDYITSFLDSGLGLCLNNRPPRQDFVYPTVAPGQAYDADEQCRFQHGVKSRQCKYGEVCSELWCLSKSNRCITNSIPAAEGTLCQTHTIDKGWCYKRVCVPFGSRPEGVDGAWGPWTPWGDCSRTCGGGVSSSSRHCDSPRPTIGGKYCLGERRRHRSCNTDDCPPGSQDFREVQCSEFDSIPFRGKFYKWKTYRGGGVKACSLTCLAEGFNFYTERAAAVVDGTPCRPDTVDICVSGECKHVGCDRVLGSDLREDKCRVCGGDGSACETIEGVFSPASPGAGYEDVVWIPKGSVHIFIQDLNLSLSHLALKGDQESLLLEGLPGTPQPHRLPLAGTTFQLRQGPDQVQSLEALGPINASLIVMVLARTELPALRYRFNAPIARDSLPPYSWHYAPWTKCSAQCAGGSQVQAVECRNQLDSSAVAPHYCSAHSKLPKRQRACNTEPCPPDWVVGNWSLCSRSCDAGVRSRSVVCQRRVSAAEEKALDDSACPQPRPPVLEACHGPTCPPEWAALDWSECTPSCGPGLRHRVVLCKSADHRATLPPAHCSPAAKPPATMRCNLRRCPPARWVAGEWGECSAQCGVGQRQRSVRCTSHTGQASHECTEALRPPTTQQCEAKCDSPTPGDGPEECKDVNKVAYCPLVLKFQFCSRAYFRQMCCKTCHGH

Target ORF information:

RefSeq Version	NM_030957.4
Organism	Homo sapiens(human)
Definition	Homo sapiens ADAM metallopeptidase with thrombospondin type 1 motif 10 (ADAMTS10), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_030957.4

ORF Insert Sequence:

ATGGCTCCCG CCTGCCAGAT CCTCCGCTGG GCCCTCGCCC TGGGGCTGGG CCTCATGTTC 
GAGGTCACGC ACGCCTTCCG GTCTCAAGAT GAGTTCCTGT CCAGTCTGGA GAGCTATGAG 
ATCGCCTTCC CCACCCGCGT GGACCACAAC GGGGCACTGC TGGCCTTCTC GCCACCTCCT 
CCCCGGAGGC AGCGCCGCGG CACGGGGGCC ACAGCCGAGT CCCGCCTCTT CTACAAAGTG 
GCCTCGCCCA GCACCCACTT CCTGCTGAAC CTGACCCGCA GCTCCCGTCT ACTGGCAGGG 
CACGTCTCCG TGGAGTACTG GACACGGGAG GGCCTGGCCT GGCAGAGGGC GGCCCGGCCC 
CACTGCCTCT ACGCTGGTCA CCTGCAGGGC CAGGCCAGCA GCTCCCATGT GGCCATCAGC 
ACCTGTGGAG GCCTGCACGG CCTGATCGTG GCAGACGAGG AAGAGTACCT GATTGAGCCC 
CTGCACGGTG GGCCCAAGGG TTCTCGGAGC CCGGAGGAAA GTGGACCACA TGTGGTGTAC 
AAGCGTTCCT CTCTGCGTCA CCCCCACCTG GACACAGCCT GTGGAGTGAG AGATGAGAAA 
CCGTGGAAAG GGCGGCCATG GTGGCTGCGG ACCTTGAAGC CACCGCCTGC CAGGCCCCTG 
GGGAATGAAA CAGAGCGTGG CCAGCCAGGC CTGAAGCGAT CGGTCAGCCG AGAGCGCTAC 
GTGGAGACCC TGGTGGTGGC TGACAAGATG ATGGTGGCCT ATCACGGGCG CCGGGATGTG 
GAGCAGTATG TCCTGGCCAT CATGAACATT GTTGCCAAAC TTTTCCAGGA CTCGAGTCTG 
GGAAGCACCG TTAACATCCT CGTAACTCGC CTCATCCTGC TCACGGAGGA CCAGCCCACT 
CTGGAGATCA CCCACCATGC CGGGAAGTCC CTGGACAGCT TCTGTAAGTG GCAGAAATCC 
ATCGTGAACC ACAGCGGCCA TGGCAATGCC ATTCCAGAGA ACGGTGTGGC TAACCATGAC 
ACAGCAGTGC TCATCACACG CTATGACATC TGCATCTACA AGAACAAACC CTGCGGCACA 
CTAGGCCTGG CCCCGGTGGG CGGAATGTGT GAGCGCGAGA GAAGCTGCAG CGTCAATGAG 
GACATTGGCC TGGCCACAGC GTTCACCATT GCCCACGAGA TCGGGCACAC ATTCGGCATG 
AACCATGACG GCGTGGGAAA CAGCTGTGGG GCCCGTGGTC AGGACCCAGC CAAGCTCATG 
GCTGCCCACA TTACCATGAA GACCAACCCA TTCGTGTGGT CATCCTGCAG CCGTGACTAC 
ATCACCAGCT TTCTAGACTC GGGCCTGGGG CTCTGCCTGA ACAACCGGCC CCCCAGACAG 
GACTTTGTGT ACCCGACAGT GGCACCGGGC CAAGCCTACG ATGCAGATGA GCAATGCCGC 
TTTCAGCATG GAGTCAAATC GCGTCAGTGT AAATACGGGG AGGTCTGCAG CGAGCTGTGG 
TGTCTGAGCA AGAGCAACCG GTGCATCACC AACAGCATCC CGGCCGCCGA GGGCACGCTG 
TGCCAGACGC ACACCATCGA CAAGGGGTGG TGCTACAAAC GGGTCTGTGT CCCCTTTGGG 
TCGCGCCCAG AGGGTGTGGA CGGAGCCTGG GGGCCGTGGA CTCCATGGGG CGACTGCAGC 
CGGACCTGTG GCGGCGGCGT GTCCTCTTCT AGCCGTCACT GCGACAGCCC CAGGCCAACC 
ATCGGGGGCA AGTACTGTCT GGGTGAGAGA AGGCGGCACC GCTCCTGCAA CACGGATGAC 
TGTCCCCCTG GCTCCCAGGA CTTCAGAGAA GTGCAGTGTT CTGAATTTGA CAGCATCCCT 
TTCCGTGGGA AATTCTACAA GTGGAAAACG TACCGGGGAG GGGGCGTGAA GGCCTGCTCG 
CTCACGTGCC TAGCGGAAGG CTTCAACTTC TACACGGAGA GGGCGGCAGC CGTGGTGGAC 
GGGACACCCT GCCGTCCAGA CACGGTGGAC ATTTGCGTCA GTGGCGAATG CAAGCACGTG 
GGCTGCGACC GAGTCCTGGG CTCCGACCTG CGGGAGGACA AGTGCCGAGT GTGTGGCGGT 
GACGGCAGTG CCTGCGAGAC CATCGAGGGC GTCTTCAGCC CAGCCTCACC TGGGGCCGGG 
TACGAGGATG TCGTCTGGAT TCCCAAAGGC TCCGTCCACA TCTTCATCCA GGATCTGAAC 
CTCTCTCTCA GTCACTTGGC CCTGAAGGGA GACCAGGAGT CCCTGCTGCT GGAGGGGCTG 
CCTGGGACCC CCCAGCCCCA CCGTCTGCCT CTAGCTGGGA CCACCTTTCA ACTGCGACAG 
GGGCCAGACC AGGTCCAGAG CCTCGAAGCC CTGGGACCGA TTAATGCATC TCTCATCGTC 
ATGGTGCTGG CCCGGACCGA GCTGCCTGCC CTCCGCTACC GCTTCAATGC CCCCATCGCC 
CGTGACTCGC TGCCCCCCTA CTCCTGGCAC TATGCGCCCT GGACCAAGTG CTCGGCCCAG 
TGTGCAGGCG GTAGCCAGGT GCAGGCGGTG GAGTGCCGCA ACCAGCTGGA CAGCTCCGCG 
GTCGCCCCCC ACTACTGCAG TGCCCACAGC AAGCTGCCCA AAAGGCAGCG CGCCTGCAAC 
ACGGAGCCTT GCCCTCCAGA CTGGGTTGTA GGGAACTGGT CGCTCTGCAG CCGCAGCTGC 
GATGCAGGCG TGCGCAGCCG CTCGGTCGTG TGCCAGCGCC GCGTCTCTGC CGCGGAGGAG 
AAGGCGCTGG ACGACAGCGC ATGCCCGCAG CCGCGCCCAC CTGTACTGGA GGCCTGCCAC 
GGCCCCACTT GCCCTCCGGA GTGGGCGGCC CTCGACTGGT CTGAGTGCAC CCCCAGCTGC 
GGGCCGGGCC TCCGCCACCG CGTGGTCCTT TGCAAGAGCG CAGACCACCG CGCCACGCTG 
CCCCCGGCGC ACTGCTCACC CGCCGCCAAG CCACCGGCCA CCATGCGCTG CAACTTGCGC 
CGCTGCCCCC CGGCCCGCTG GGTGGCTGGC GAGTGGGGTG AGTGCTCTGC ACAGTGCGGC 
GTCGGGCAGC GGCAGCGCTC GGTGCGCTGC ACCAGCCACA CGGGCCAGGC GTCGCACGAG 
TGCACGGAGG CCCTGCGGCC GCCCACCACG CAGCAGTGTG AGGCCAAGTG CGACAGCCCA 
ACCCCCGGGG ACGGCCCTGA AGAGTGCAAG GATGTGAACA AGGTCGCCTA CTGCCCCCTG 
GTGCTCAAAT TTCAGTTCTG CAGCCGAGCC TACTTCCGCC AGATGTGCTG CAAAACCTGC 
CATGGCCACT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ADAMTS10 ( NM_030957.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_112219.3 Homo sapiens ADAM metallopeptidase with thrombospondin type 1 motif 10 (ADAMTS10), transcript variant 1, mRNA.

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CloneID	OHu20510
Clone ID Related Accession (Same CDS sequence)	NM_030957.4 , XM_017027338.1 , XM_017027338.2 , NM_030957.3
Accession Version	NM_030957.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3312bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-02
Organism	Homo sapiens(human)
Product	A disintegrin and metalloproteinase with thrombospondin motifs 10 isoform 1 preproprotein
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from CN431169.1, AB209515.1, AF163762.1, BC029308.1, AC130469.2, AK131414.1 and BF510205.1. This sequence is a reference standard in the RefSeqGene project. On Aug 31, 2013 this sequence version replaced NM_030957.2. Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## inferred exon combination :: based on alignments, homology ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGCTCCCG CCTGCCAGAT CCTCCGCTGG GCCCTCGCCC TGGGGCTGGG CCTCATGTTC 
GAGGTCACGC ACGCCTTCCG GTCTCAAGAT GAGTTCCTGT CCAGTCTGGA GAGCTATGAG 
ATCGCCTTCC CCACCCGCGT GGACCACAAC GGGGCACTGC TGGCCTTCTC GCCACCTCCT 
CCCCGGAGGC AGCGCCGCGG CACGGGGGCC ACAGCCGAGT CCCGCCTCTT CTACAAAGTG 
GCCTCGCCCA GCACCCACTT CCTGCTGAAC CTGACCCGCA GCTCCCGTCT ACTGGCAGGG 
CACGTCTCCG TGGAGTACTG GACACGGGAG GGCCTGGCCT GGCAGAGGGC GGCCCGGCCC 
CACTGCCTCT ACGCTGGTCA CCTGCAGGGC CAGGCCAGCA GCTCCCATGT GGCCATCAGC 
ACCTGTGGAG GCCTGCACGG CCTGATCGTG GCAGACGAGG AAGAGTACCT GATTGAGCCC 
CTGCACGGTG GGCCCAAGGG TTCTCGGAGC CCGGAGGAAA GTGGACCACA TGTGGTGTAC 
AAGCGTTCCT CTCTGCGTCA CCCCCACCTG GACACAGCCT GTGGAGTGAG AGATGAGAAA 
CCGTGGAAAG GGCGGCCATG GTGGCTGCGG ACCTTGAAGC CACCGCCTGC CAGGCCCCTG 
GGGAATGAAA CAGAGCGTGG CCAGCCAGGC CTGAAGCGAT CGGTCAGCCG AGAGCGCTAC 
GTGGAGACCC TGGTGGTGGC TGACAAGATG ATGGTGGCCT ATCACGGGCG CCGGGATGTG 
GAGCAGTATG TCCTGGCCAT CATGAACATT GTTGCCAAAC TTTTCCAGGA CTCGAGTCTG 
GGAAGCACCG TTAACATCCT CGTAACTCGC CTCATCCTGC TCACGGAGGA CCAGCCCACT 
CTGGAGATCA CCCACCATGC CGGGAAGTCC CTGGACAGCT TCTGTAAGTG GCAGAAATCC 
ATCGTGAACC ACAGCGGCCA TGGCAATGCC ATTCCAGAGA ACGGTGTGGC TAACCATGAC 
ACAGCAGTGC TCATCACACG CTATGACATC TGCATCTACA AGAACAAACC CTGCGGCACA 
CTAGGCCTGG CCCCGGTGGG CGGAATGTGT GAGCGCGAGA GAAGCTGCAG CGTCAATGAG 
GACATTGGCC TGGCCACAGC GTTCACCATT GCCCACGAGA TCGGGCACAC ATTCGGCATG 
AACCATGACG GCGTGGGAAA CAGCTGTGGG GCCCGTGGTC AGGACCCAGC CAAGCTCATG 
GCTGCCCACA TTACCATGAA GACCAACCCA TTCGTGTGGT CATCCTGCAG CCGTGACTAC 
ATCACCAGCT TTCTAGACTC GGGCCTGGGG CTCTGCCTGA ACAACCGGCC CCCCAGACAG 
GACTTTGTGT ACCCGACAGT GGCACCGGGC CAAGCCTACG ATGCAGATGA GCAATGCCGC 
TTTCAGCATG GAGTCAAATC GCGTCAGTGT AAATACGGGG AGGTCTGCAG CGAGCTGTGG 
TGTCTGAGCA AGAGCAACCG GTGCATCACC AACAGCATCC CGGCCGCCGA GGGCACGCTG 
TGCCAGACGC ACACCATCGA CAAGGGGTGG TGCTACAAAC GGGTCTGTGT CCCCTTTGGG 
TCGCGCCCAG AGGGTGTGGA CGGAGCCTGG GGGCCGTGGA CTCCATGGGG CGACTGCAGC 
CGGACCTGTG GCGGCGGCGT GTCCTCTTCT AGCCGTCACT GCGACAGCCC CAGGCCAACC 
ATCGGGGGCA AGTACTGTCT GGGTGAGAGA AGGCGGCACC GCTCCTGCAA CACGGATGAC 
TGTCCCCCTG GCTCCCAGGA CTTCAGAGAA GTGCAGTGTT CTGAATTTGA CAGCATCCCT 
TTCCGTGGGA AATTCTACAA GTGGAAAACG TACCGGGGAG GGGGCGTGAA GGCCTGCTCG 
CTCACGTGCC TAGCGGAAGG CTTCAACTTC TACACGGAGA GGGCGGCAGC CGTGGTGGAC 
GGGACACCCT GCCGTCCAGA CACGGTGGAC ATTTGCGTCA GTGGCGAATG CAAGCACGTG 
GGCTGCGACC GAGTCCTGGG CTCCGACCTG CGGGAGGACA AGTGCCGAGT GTGTGGCGGT 
GACGGCAGTG CCTGCGAGAC CATCGAGGGC GTCTTCAGCC CAGCCTCACC TGGGGCCGGG 
TACGAGGATG TCGTCTGGAT TCCCAAAGGC TCCGTCCACA TCTTCATCCA GGATCTGAAC 
CTCTCTCTCA GTCACTTGGC CCTGAAGGGA GACCAGGAGT CCCTGCTGCT GGAGGGGCTG 
CCTGGGACCC CCCAGCCCCA CCGTCTGCCT CTAGCTGGGA CCACCTTTCA ACTGCGACAG 
GGGCCAGACC AGGTCCAGAG CCTCGAAGCC CTGGGACCGA TTAATGCATC TCTCATCGTC 
ATGGTGCTGG CCCGGACCGA GCTGCCTGCC CTCCGCTACC GCTTCAATGC CCCCATCGCC 
CGTGACTCGC TGCCCCCCTA CTCCTGGCAC TATGCGCCCT GGACCAAGTG CTCGGCCCAG 
TGTGCAGGCG GTAGCCAGGT GCAGGCGGTG GAGTGCCGCA ACCAGCTGGA CAGCTCCGCG 
GTCGCCCCCC ACTACTGCAG TGCCCACAGC AAGCTGCCCA AAAGGCAGCG CGCCTGCAAC 
ACGGAGCCTT GCCCTCCAGA CTGGGTTGTA GGGAACTGGT CGCTCTGCAG CCGCAGCTGC 
GATGCAGGCG TGCGCAGCCG CTCGGTCGTG TGCCAGCGCC GCGTCTCTGC CGCGGAGGAG 
AAGGCGCTGG ACGACAGCGC ATGCCCGCAG CCGCGCCCAC CTGTACTGGA GGCCTGCCAC 
GGCCCCACTT GCCCTCCGGA GTGGGCGGCC CTCGACTGGT CTGAGTGCAC CCCCAGCTGC 
GGGCCGGGCC TCCGCCACCG CGTGGTCCTT TGCAAGAGCG CAGACCACCG CGCCACGCTG 
CCCCCGGCGC ACTGCTCACC CGCCGCCAAG CCACCGGCCA CCATGCGCTG CAACTTGCGC 
CGCTGCCCCC CGGCCCGCTG GGTGGCTGGC GAGTGGGGTG AGTGCTCTGC ACAGTGCGGC 
GTCGGGCAGC GGCAGCGCTC GGTGCGCTGC ACCAGCCACA CGGGCCAGGC GTCGCACGAG 
TGCACGGAGG CCCTGCGGCC GCCCACCACG CAGCAGTGTG AGGCCAAGTG CGACAGCCCA 
ACCCCCGGGG ACGGCCCTGA AGAGTGCAAG GATGTGAACA AGGTCGCCTA CTGCCCCCTG 
GTGCTCAAAT TTCAGTTCTG CAGCCGAGCC TACTTCCGCC AGATGTGCTG CAAAACCTGC 
CATGGCCACT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_112219.3
CDS	307..3618
Translation	MAPACQILRWALALGLGLMFEVTHAFRSQDEFLSSLESYEIAFPTRVDHNGALLAFSPPPPRRQRRGTGATAESRLFYKVASPSTHFLLNLTRSSRLLAGHVSVEYWTREGLAWQRAARPHCLYAGHLQGQASSSHVAISTCGGLHGLIVADEEEYLIEPLHGGPKGSRSPEESGPHVVYKRSSLRHPHLDTACGVRDEKPWKGRPWWLRTLKPPPARPLGNETERGQPGLKRSVSRERYVETLVVADKMMVAYHGRRDVEQYVLAIMNIVAKLFQDSSLGSTVNILVTRLILLTEDQPTLEITHHAGKSLDSFCKWQKSIVNHSGHGNAIPENGVANHDTAVLITRYDICIYKNKPCGTLGLAPVGGMCERERSCSVNEDIGLATAFTIAHEIGHTFGMNHDGVGNSCGARGQDPAKLMAAHITMKTNPFVWSSCSRDYITSFLDSGLGLCLNNRPPRQDFVYPTVAPGQAYDADEQCRFQHGVKSRQCKYGEVCSELWCLSKSNRCITNSIPAAEGTLCQTHTIDKGWCYKRVCVPFGSRPEGVDGAWGPWTPWGDCSRTCGGGVSSSSRHCDSPRPTIGGKYCLGERRRHRSCNTDDCPPGSQDFREVQCSEFDSIPFRGKFYKWKTYRGGGVKACSLTCLAEGFNFYTERAAAVVDGTPCRPDTVDICVSGECKHVGCDRVLGSDLREDKCRVCGGDGSACETIEGVFSPASPGAGYEDVVWIPKGSVHIFIQDLNLSLSHLALKGDQESLLLEGLPGTPQPHRLPLAGTTFQLRQGPDQVQSLEALGPINASLIVMVLARTELPALRYRFNAPIARDSLPPYSWHYAPWTKCSAQCAGGSQVQAVECRNQLDSSAVAPHYCSAHSKLPKRQRACNTEPCPPDWVVGNWSLCSRSCDAGVRSRSVVCQRRVSAAEEKALDDSACPQPRPPVLEACHGPTCPPEWAALDWSECTPSCGPGLRHRVVLCKSADHRATLPPAHCSPAAKPPATMRCNLRRCPPARWVAGEWGECSAQCGVGQRQRSVRCTSHTGQASHECTEALRPPTTQQCEAKCDSPTPGDGPEECKDVNKVAYCPLVLKFQFCSRAYFRQMCCKTCHGH

Target ORF information:

RefSeq Version	NM_030957.3
Organism	Homo sapiens(human)
Definition	Homo sapiens ADAM metallopeptidase with thrombospondin type 1 motif 10 (ADAMTS10), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_030957.3

ORF Insert Sequence:

ATGGCTCCCG CCTGCCAGAT CCTCCGCTGG GCCCTCGCCC TGGGGCTGGG CCTCATGTTC 
GAGGTCACGC ACGCCTTCCG GTCTCAAGAT GAGTTCCTGT CCAGTCTGGA GAGCTATGAG 
ATCGCCTTCC CCACCCGCGT GGACCACAAC GGGGCACTGC TGGCCTTCTC GCCACCTCCT 
CCCCGGAGGC AGCGCCGCGG CACGGGGGCC ACAGCCGAGT CCCGCCTCTT CTACAAAGTG 
GCCTCGCCCA GCACCCACTT CCTGCTGAAC CTGACCCGCA GCTCCCGTCT ACTGGCAGGG 
CACGTCTCCG TGGAGTACTG GACACGGGAG GGCCTGGCCT GGCAGAGGGC GGCCCGGCCC 
CACTGCCTCT ACGCTGGTCA CCTGCAGGGC CAGGCCAGCA GCTCCCATGT GGCCATCAGC 
ACCTGTGGAG GCCTGCACGG CCTGATCGTG GCAGACGAGG AAGAGTACCT GATTGAGCCC 
CTGCACGGTG GGCCCAAGGG TTCTCGGAGC CCGGAGGAAA GTGGACCACA TGTGGTGTAC 
AAGCGTTCCT CTCTGCGTCA CCCCCACCTG GACACAGCCT GTGGAGTGAG AGATGAGAAA 
CCGTGGAAAG GGCGGCCATG GTGGCTGCGG ACCTTGAAGC CACCGCCTGC CAGGCCCCTG 
GGGAATGAAA CAGAGCGTGG CCAGCCAGGC CTGAAGCGAT CGGTCAGCCG AGAGCGCTAC 
GTGGAGACCC TGGTGGTGGC TGACAAGATG ATGGTGGCCT ATCACGGGCG CCGGGATGTG 
GAGCAGTATG TCCTGGCCAT CATGAACATT GTTGCCAAAC TTTTCCAGGA CTCGAGTCTG 
GGAAGCACCG TTAACATCCT CGTAACTCGC CTCATCCTGC TCACGGAGGA CCAGCCCACT 
CTGGAGATCA CCCACCATGC CGGGAAGTCC CTGGACAGCT TCTGTAAGTG GCAGAAATCC 
ATCGTGAACC ACAGCGGCCA TGGCAATGCC ATTCCAGAGA ACGGTGTGGC TAACCATGAC 
ACAGCAGTGC TCATCACACG CTATGACATC TGCATCTACA AGAACAAACC CTGCGGCACA 
CTAGGCCTGG CCCCGGTGGG CGGAATGTGT GAGCGCGAGA GAAGCTGCAG CGTCAATGAG 
GACATTGGCC TGGCCACAGC GTTCACCATT GCCCACGAGA TCGGGCACAC ATTCGGCATG 
AACCATGACG GCGTGGGAAA CAGCTGTGGG GCCCGTGGTC AGGACCCAGC CAAGCTCATG 
GCTGCCCACA TTACCATGAA GACCAACCCA TTCGTGTGGT CATCCTGCAG CCGTGACTAC 
ATCACCAGCT TTCTAGACTC GGGCCTGGGG CTCTGCCTGA ACAACCGGCC CCCCAGACAG 
GACTTTGTGT ACCCGACAGT GGCACCGGGC CAAGCCTACG ATGCAGATGA GCAATGCCGC 
TTTCAGCATG GAGTCAAATC GCGTCAGTGT AAATACGGGG AGGTCTGCAG CGAGCTGTGG 
TGTCTGAGCA AGAGCAACCG GTGCATCACC AACAGCATCC CGGCCGCCGA GGGCACGCTG 
TGCCAGACGC ACACCATCGA CAAGGGGTGG TGCTACAAAC GGGTCTGTGT CCCCTTTGGG 
TCGCGCCCAG AGGGTGTGGA CGGAGCCTGG GGGCCGTGGA CTCCATGGGG CGACTGCAGC 
CGGACCTGTG GCGGCGGCGT GTCCTCTTCT AGCCGTCACT GCGACAGCCC CAGGCCAACC 
ATCGGGGGCA AGTACTGTCT GGGTGAGAGA AGGCGGCACC GCTCCTGCAA CACGGATGAC 
TGTCCCCCTG GCTCCCAGGA CTTCAGAGAA GTGCAGTGTT CTGAATTTGA CAGCATCCCT 
TTCCGTGGGA AATTCTACAA GTGGAAAACG TACCGGGGAG GGGGCGTGAA GGCCTGCTCG 
CTCACGTGCC TAGCGGAAGG CTTCAACTTC TACACGGAGA GGGCGGCAGC CGTGGTGGAC 
GGGACACCCT GCCGTCCAGA CACGGTGGAC ATTTGCGTCA GTGGCGAATG CAAGCACGTG 
GGCTGCGACC GAGTCCTGGG CTCCGACCTG CGGGAGGACA AGTGCCGAGT GTGTGGCGGT 
GACGGCAGTG CCTGCGAGAC CATCGAGGGC GTCTTCAGCC CAGCCTCACC TGGGGCCGGG 
TACGAGGATG TCGTCTGGAT TCCCAAAGGC TCCGTCCACA TCTTCATCCA GGATCTGAAC 
CTCTCTCTCA GTCACTTGGC CCTGAAGGGA GACCAGGAGT CCCTGCTGCT GGAGGGGCTG 
CCTGGGACCC CCCAGCCCCA CCGTCTGCCT CTAGCTGGGA CCACCTTTCA ACTGCGACAG 
GGGCCAGACC AGGTCCAGAG CCTCGAAGCC CTGGGACCGA TTAATGCATC TCTCATCGTC 
ATGGTGCTGG CCCGGACCGA GCTGCCTGCC CTCCGCTACC GCTTCAATGC CCCCATCGCC 
CGTGACTCGC TGCCCCCCTA CTCCTGGCAC TATGCGCCCT GGACCAAGTG CTCGGCCCAG 
TGTGCAGGCG GTAGCCAGGT GCAGGCGGTG GAGTGCCGCA ACCAGCTGGA CAGCTCCGCG 
GTCGCCCCCC ACTACTGCAG TGCCCACAGC AAGCTGCCCA AAAGGCAGCG CGCCTGCAAC 
ACGGAGCCTT GCCCTCCAGA CTGGGTTGTA GGGAACTGGT CGCTCTGCAG CCGCAGCTGC 
GATGCAGGCG TGCGCAGCCG CTCGGTCGTG TGCCAGCGCC GCGTCTCTGC CGCGGAGGAG 
AAGGCGCTGG ACGACAGCGC ATGCCCGCAG CCGCGCCCAC CTGTACTGGA GGCCTGCCAC 
GGCCCCACTT GCCCTCCGGA GTGGGCGGCC CTCGACTGGT CTGAGTGCAC CCCCAGCTGC 
GGGCCGGGCC TCCGCCACCG CGTGGTCCTT TGCAAGAGCG CAGACCACCG CGCCACGCTG 
CCCCCGGCGC ACTGCTCACC CGCCGCCAAG CCACCGGCCA CCATGCGCTG CAACTTGCGC 
CGCTGCCCCC CGGCCCGCTG GGTGGCTGGC GAGTGGGGTG AGTGCTCTGC ACAGTGCGGC 
GTCGGGCAGC GGCAGCGCTC GGTGCGCTGC ACCAGCCACA CGGGCCAGGC GTCGCACGAG 
TGCACGGAGG CCCTGCGGCC GCCCACCACG CAGCAGTGTG AGGCCAAGTG CGACAGCCCA 
ACCCCCGGGG ACGGCCCTGA AGAGTGCAAG GATGTGAACA AGGTCGCCTA CTGCCCCCTG 
GTGCTCAAAT TTCAGTTCTG CAGCCGAGCC TACTTCCGCC AGATGTGCTG CAAAACCTGC 
CATGGCCACT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ADAMTS10 ( XM_017027338.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016882827.1 Homo sapiens ADAM metallopeptidase with thrombospondin type 1 motif 10 (ADAMTS10), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu20510
Clone ID Related Accession (Same CDS sequence)	NM_030957.4 , XM_017027338.1 , XM_017027338.2 , NM_030957.3
Accession Version	XM_017027338.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3312bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	A disintegrin and metalloproteinase with thrombospondin motifs 10 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000019.10) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCTCCCG CCTGCCAGAT CCTCCGCTGG GCCCTCGCCC TGGGGCTGGG CCTCATGTTC 
GAGGTCACGC ACGCCTTCCG GTCTCAAGAT GAGTTCCTGT CCAGTCTGGA GAGCTATGAG 
ATCGCCTTCC CCACCCGCGT GGACCACAAC GGGGCACTGC TGGCCTTCTC GCCACCTCCT 
CCCCGGAGGC AGCGCCGCGG CACGGGGGCC ACAGCCGAGT CCCGCCTCTT CTACAAAGTG 
GCCTCGCCCA GCACCCACTT CCTGCTGAAC CTGACCCGCA GCTCCCGTCT ACTGGCAGGG 
CACGTCTCCG TGGAGTACTG GACACGGGAG GGCCTGGCCT GGCAGAGGGC GGCCCGGCCC 
CACTGCCTCT ACGCTGGTCA CCTGCAGGGC CAGGCCAGCA GCTCCCATGT GGCCATCAGC 
ACCTGTGGAG GCCTGCACGG CCTGATCGTG GCAGACGAGG AAGAGTACCT GATTGAGCCC 
CTGCACGGTG GGCCCAAGGG TTCTCGGAGC CCGGAGGAAA GTGGACCACA TGTGGTGTAC 
AAGCGTTCCT CTCTGCGTCA CCCCCACCTG GACACAGCCT GTGGAGTGAG AGATGAGAAA 
CCGTGGAAAG GGCGGCCATG GTGGCTGCGG ACCTTGAAGC CACCGCCTGC CAGGCCCCTG 
GGGAATGAAA CAGAGCGTGG CCAGCCAGGC CTGAAGCGAT CGGTCAGCCG AGAGCGCTAC 
GTGGAGACCC TGGTGGTGGC TGACAAGATG ATGGTGGCCT ATCACGGGCG CCGGGATGTG 
GAGCAGTATG TCCTGGCCAT CATGAACATT GTTGCCAAAC TTTTCCAGGA CTCGAGTCTG 
GGAAGCACCG TTAACATCCT CGTAACTCGC CTCATCCTGC TCACGGAGGA CCAGCCCACT 
CTGGAGATCA CCCACCATGC CGGGAAGTCC CTGGACAGCT TCTGTAAGTG GCAGAAATCC 
ATCGTGAACC ACAGCGGCCA TGGCAATGCC ATTCCAGAGA ACGGTGTGGC TAACCATGAC 
ACAGCAGTGC TCATCACACG CTATGACATC TGCATCTACA AGAACAAACC CTGCGGCACA 
CTAGGCCTGG CCCCGGTGGG CGGAATGTGT GAGCGCGAGA GAAGCTGCAG CGTCAATGAG 
GACATTGGCC TGGCCACAGC GTTCACCATT GCCCACGAGA TCGGGCACAC ATTCGGCATG 
AACCATGACG GCGTGGGAAA CAGCTGTGGG GCCCGTGGTC AGGACCCAGC CAAGCTCATG 
GCTGCCCACA TTACCATGAA GACCAACCCA TTCGTGTGGT CATCCTGCAG CCGTGACTAC 
ATCACCAGCT TTCTAGACTC GGGCCTGGGG CTCTGCCTGA ACAACCGGCC CCCCAGACAG 
GACTTTGTGT ACCCGACAGT GGCACCGGGC CAAGCCTACG ATGCAGATGA GCAATGCCGC 
TTTCAGCATG GAGTCAAATC GCGTCAGTGT AAATACGGGG AGGTCTGCAG CGAGCTGTGG 
TGTCTGAGCA AGAGCAACCG GTGCATCACC AACAGCATCC CGGCCGCCGA GGGCACGCTG 
TGCCAGACGC ACACCATCGA CAAGGGGTGG TGCTACAAAC GGGTCTGTGT CCCCTTTGGG 
TCGCGCCCAG AGGGTGTGGA CGGAGCCTGG GGGCCGTGGA CTCCATGGGG CGACTGCAGC 
CGGACCTGTG GCGGCGGCGT GTCCTCTTCT AGCCGTCACT GCGACAGCCC CAGGCCAACC 
ATCGGGGGCA AGTACTGTCT GGGTGAGAGA AGGCGGCACC GCTCCTGCAA CACGGATGAC 
TGTCCCCCTG GCTCCCAGGA CTTCAGAGAA GTGCAGTGTT CTGAATTTGA CAGCATCCCT 
TTCCGTGGGA AATTCTACAA GTGGAAAACG TACCGGGGAG GGGGCGTGAA GGCCTGCTCG 
CTCACGTGCC TAGCGGAAGG CTTCAACTTC TACACGGAGA GGGCGGCAGC CGTGGTGGAC 
GGGACACCCT GCCGTCCAGA CACGGTGGAC ATTTGCGTCA GTGGCGAATG CAAGCACGTG 
GGCTGCGACC GAGTCCTGGG CTCCGACCTG CGGGAGGACA AGTGCCGAGT GTGTGGCGGT 
GACGGCAGTG CCTGCGAGAC CATCGAGGGC GTCTTCAGCC CAGCCTCACC TGGGGCCGGG 
TACGAGGATG TCGTCTGGAT TCCCAAAGGC TCCGTCCACA TCTTCATCCA GGATCTGAAC 
CTCTCTCTCA GTCACTTGGC CCTGAAGGGA GACCAGGAGT CCCTGCTGCT GGAGGGGCTG 
CCTGGGACCC CCCAGCCCCA CCGTCTGCCT CTAGCTGGGA CCACCTTTCA ACTGCGACAG 
GGGCCAGACC AGGTCCAGAG CCTCGAAGCC CTGGGACCGA TTAATGCATC TCTCATCGTC 
ATGGTGCTGG CCCGGACCGA GCTGCCTGCC CTCCGCTACC GCTTCAATGC CCCCATCGCC 
CGTGACTCGC TGCCCCCCTA CTCCTGGCAC TATGCGCCCT GGACCAAGTG CTCGGCCCAG 
TGTGCAGGCG GTAGCCAGGT GCAGGCGGTG GAGTGCCGCA ACCAGCTGGA CAGCTCCGCG 
GTCGCCCCCC ACTACTGCAG TGCCCACAGC AAGCTGCCCA AAAGGCAGCG CGCCTGCAAC 
ACGGAGCCTT GCCCTCCAGA CTGGGTTGTA GGGAACTGGT CGCTCTGCAG CCGCAGCTGC 
GATGCAGGCG TGCGCAGCCG CTCGGTCGTG TGCCAGCGCC GCGTCTCTGC CGCGGAGGAG 
AAGGCGCTGG ACGACAGCGC ATGCCCGCAG CCGCGCCCAC CTGTACTGGA GGCCTGCCAC 
GGCCCCACTT GCCCTCCGGA GTGGGCGGCC CTCGACTGGT CTGAGTGCAC CCCCAGCTGC 
GGGCCGGGCC TCCGCCACCG CGTGGTCCTT TGCAAGAGCG CAGACCACCG CGCCACGCTG 
CCCCCGGCGC ACTGCTCACC CGCCGCCAAG CCACCGGCCA CCATGCGCTG CAACTTGCGC 
CGCTGCCCCC CGGCCCGCTG GGTGGCTGGC GAGTGGGGTG AGTGCTCTGC ACAGTGCGGC 
GTCGGGCAGC GGCAGCGCTC GGTGCGCTGC ACCAGCCACA CGGGCCAGGC GTCGCACGAG 
TGCACGGAGG CCCTGCGGCC GCCCACCACG CAGCAGTGTG AGGCCAAGTG CGACAGCCCA 
ACCCCCGGGG ACGGCCCTGA AGAGTGCAAG GATGTGAACA AGGTCGCCTA CTGCCCCCTG 
GTGCTCAAAT TTCAGTTCTG CAGCCGAGCC TACTTCCGCC AGATGTGCTG CAAAACCTGC 
CATGGCCACT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016882827.1
CDS	163..3474
Translation	MAPACQILRWALALGLGLMFEVTHAFRSQDEFLSSLESYEIAFPTRVDHNGALLAFSPPPPRRQRRGTGATAESRLFYKVASPSTHFLLNLTRSSRLLAGHVSVEYWTREGLAWQRAARPHCLYAGHLQGQASSSHVAISTCGGLHGLIVADEEEYLIEPLHGGPKGSRSPEESGPHVVYKRSSLRHPHLDTACGVRDEKPWKGRPWWLRTLKPPPARPLGNETERGQPGLKRSVSRERYVETLVVADKMMVAYHGRRDVEQYVLAIMNIVAKLFQDSSLGSTVNILVTRLILLTEDQPTLEITHHAGKSLDSFCKWQKSIVNHSGHGNAIPENGVANHDTAVLITRYDICIYKNKPCGTLGLAPVGGMCERERSCSVNEDIGLATAFTIAHEIGHTFGMNHDGVGNSCGARGQDPAKLMAAHITMKTNPFVWSSCSRDYITSFLDSGLGLCLNNRPPRQDFVYPTVAPGQAYDADEQCRFQHGVKSRQCKYGEVCSELWCLSKSNRCITNSIPAAEGTLCQTHTIDKGWCYKRVCVPFGSRPEGVDGAWGPWTPWGDCSRTCGGGVSSSSRHCDSPRPTIGGKYCLGERRRHRSCNTDDCPPGSQDFREVQCSEFDSIPFRGKFYKWKTYRGGGVKACSLTCLAEGFNFYTERAAAVVDGTPCRPDTVDICVSGECKHVGCDRVLGSDLREDKCRVCGGDGSACETIEGVFSPASPGAGYEDVVWIPKGSVHIFIQDLNLSLSHLALKGDQESLLLEGLPGTPQPHRLPLAGTTFQLRQGPDQVQSLEALGPINASLIVMVLARTELPALRYRFNAPIARDSLPPYSWHYAPWTKCSAQCAGGSQVQAVECRNQLDSSAVAPHYCSAHSKLPKRQRACNTEPCPPDWVVGNWSLCSRSCDAGVRSRSVVCQRRVSAAEEKALDDSACPQPRPPVLEACHGPTCPPEWAALDWSECTPSCGPGLRHRVVLCKSADHRATLPPAHCSPAAKPPATMRCNLRRCPPARWVAGEWGECSAQCGVGQRQRSVRCTSHTGQASHECTEALRPPTTQQCEAKCDSPTPGDGPEECKDVNKVAYCPLVLKFQFCSRAYFRQMCCKTCHGH

Target ORF information:

RefSeq Version	XM_017027338.1
Organism	Homo sapiens(human)
Definition	Homo sapiens ADAM metallopeptidase with thrombospondin type 1 motif 10 (ADAMTS10), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017027338.1

ORF Insert Sequence:

ATGGCTCCCG CCTGCCAGAT CCTCCGCTGG GCCCTCGCCC TGGGGCTGGG CCTCATGTTC 
GAGGTCACGC ACGCCTTCCG GTCTCAAGAT GAGTTCCTGT CCAGTCTGGA GAGCTATGAG 
ATCGCCTTCC CCACCCGCGT GGACCACAAC GGGGCACTGC TGGCCTTCTC GCCACCTCCT 
CCCCGGAGGC AGCGCCGCGG CACGGGGGCC ACAGCCGAGT CCCGCCTCTT CTACAAAGTG 
GCCTCGCCCA GCACCCACTT CCTGCTGAAC CTGACCCGCA GCTCCCGTCT ACTGGCAGGG 
CACGTCTCCG TGGAGTACTG GACACGGGAG GGCCTGGCCT GGCAGAGGGC GGCCCGGCCC 
CACTGCCTCT ACGCTGGTCA CCTGCAGGGC CAGGCCAGCA GCTCCCATGT GGCCATCAGC 
ACCTGTGGAG GCCTGCACGG CCTGATCGTG GCAGACGAGG AAGAGTACCT GATTGAGCCC 
CTGCACGGTG GGCCCAAGGG TTCTCGGAGC CCGGAGGAAA GTGGACCACA TGTGGTGTAC 
AAGCGTTCCT CTCTGCGTCA CCCCCACCTG GACACAGCCT GTGGAGTGAG AGATGAGAAA 
CCGTGGAAAG GGCGGCCATG GTGGCTGCGG ACCTTGAAGC CACCGCCTGC CAGGCCCCTG 
GGGAATGAAA CAGAGCGTGG CCAGCCAGGC CTGAAGCGAT CGGTCAGCCG AGAGCGCTAC 
GTGGAGACCC TGGTGGTGGC TGACAAGATG ATGGTGGCCT ATCACGGGCG CCGGGATGTG 
GAGCAGTATG TCCTGGCCAT CATGAACATT GTTGCCAAAC TTTTCCAGGA CTCGAGTCTG 
GGAAGCACCG TTAACATCCT CGTAACTCGC CTCATCCTGC TCACGGAGGA CCAGCCCACT 
CTGGAGATCA CCCACCATGC CGGGAAGTCC CTGGACAGCT TCTGTAAGTG GCAGAAATCC 
ATCGTGAACC ACAGCGGCCA TGGCAATGCC ATTCCAGAGA ACGGTGTGGC TAACCATGAC 
ACAGCAGTGC TCATCACACG CTATGACATC TGCATCTACA AGAACAAACC CTGCGGCACA 
CTAGGCCTGG CCCCGGTGGG CGGAATGTGT GAGCGCGAGA GAAGCTGCAG CGTCAATGAG 
GACATTGGCC TGGCCACAGC GTTCACCATT GCCCACGAGA TCGGGCACAC ATTCGGCATG 
AACCATGACG GCGTGGGAAA CAGCTGTGGG GCCCGTGGTC AGGACCCAGC CAAGCTCATG 
GCTGCCCACA TTACCATGAA GACCAACCCA TTCGTGTGGT CATCCTGCAG CCGTGACTAC 
ATCACCAGCT TTCTAGACTC GGGCCTGGGG CTCTGCCTGA ACAACCGGCC CCCCAGACAG 
GACTTTGTGT ACCCGACAGT GGCACCGGGC CAAGCCTACG ATGCAGATGA GCAATGCCGC 
TTTCAGCATG GAGTCAAATC GCGTCAGTGT AAATACGGGG AGGTCTGCAG CGAGCTGTGG 
TGTCTGAGCA AGAGCAACCG GTGCATCACC AACAGCATCC CGGCCGCCGA GGGCACGCTG 
TGCCAGACGC ACACCATCGA CAAGGGGTGG TGCTACAAAC GGGTCTGTGT CCCCTTTGGG 
TCGCGCCCAG AGGGTGTGGA CGGAGCCTGG GGGCCGTGGA CTCCATGGGG CGACTGCAGC 
CGGACCTGTG GCGGCGGCGT GTCCTCTTCT AGCCGTCACT GCGACAGCCC CAGGCCAACC 
ATCGGGGGCA AGTACTGTCT GGGTGAGAGA AGGCGGCACC GCTCCTGCAA CACGGATGAC 
TGTCCCCCTG GCTCCCAGGA CTTCAGAGAA GTGCAGTGTT CTGAATTTGA CAGCATCCCT 
TTCCGTGGGA AATTCTACAA GTGGAAAACG TACCGGGGAG GGGGCGTGAA GGCCTGCTCG 
CTCACGTGCC TAGCGGAAGG CTTCAACTTC TACACGGAGA GGGCGGCAGC CGTGGTGGAC 
GGGACACCCT GCCGTCCAGA CACGGTGGAC ATTTGCGTCA GTGGCGAATG CAAGCACGTG 
GGCTGCGACC GAGTCCTGGG CTCCGACCTG CGGGAGGACA AGTGCCGAGT GTGTGGCGGT 
GACGGCAGTG CCTGCGAGAC CATCGAGGGC GTCTTCAGCC CAGCCTCACC TGGGGCCGGG 
TACGAGGATG TCGTCTGGAT TCCCAAAGGC TCCGTCCACA TCTTCATCCA GGATCTGAAC 
CTCTCTCTCA GTCACTTGGC CCTGAAGGGA GACCAGGAGT CCCTGCTGCT GGAGGGGCTG 
CCTGGGACCC CCCAGCCCCA CCGTCTGCCT CTAGCTGGGA CCACCTTTCA ACTGCGACAG 
GGGCCAGACC AGGTCCAGAG CCTCGAAGCC CTGGGACCGA TTAATGCATC TCTCATCGTC 
ATGGTGCTGG CCCGGACCGA GCTGCCTGCC CTCCGCTACC GCTTCAATGC CCCCATCGCC 
CGTGACTCGC TGCCCCCCTA CTCCTGGCAC TATGCGCCCT GGACCAAGTG CTCGGCCCAG 
TGTGCAGGCG GTAGCCAGGT GCAGGCGGTG GAGTGCCGCA ACCAGCTGGA CAGCTCCGCG 
GTCGCCCCCC ACTACTGCAG TGCCCACAGC AAGCTGCCCA AAAGGCAGCG CGCCTGCAAC 
ACGGAGCCTT GCCCTCCAGA CTGGGTTGTA GGGAACTGGT CGCTCTGCAG CCGCAGCTGC 
GATGCAGGCG TGCGCAGCCG CTCGGTCGTG TGCCAGCGCC GCGTCTCTGC CGCGGAGGAG 
AAGGCGCTGG ACGACAGCGC ATGCCCGCAG CCGCGCCCAC CTGTACTGGA GGCCTGCCAC 
GGCCCCACTT GCCCTCCGGA GTGGGCGGCC CTCGACTGGT CTGAGTGCAC CCCCAGCTGC 
GGGCCGGGCC TCCGCCACCG CGTGGTCCTT TGCAAGAGCG CAGACCACCG CGCCACGCTG 
CCCCCGGCGC ACTGCTCACC CGCCGCCAAG CCACCGGCCA CCATGCGCTG CAACTTGCGC 
CGCTGCCCCC CGGCCCGCTG GGTGGCTGGC GAGTGGGGTG AGTGCTCTGC ACAGTGCGGC 
GTCGGGCAGC GGCAGCGCTC GGTGCGCTGC ACCAGCCACA CGGGCCAGGC GTCGCACGAG 
TGCACGGAGG CCCTGCGGCC GCCCACCACG CAGCAGTGTG AGGCCAAGTG CGACAGCCCA 
ACCCCCGGGG ACGGCCCTGA AGAGTGCAAG GATGTGAACA AGGTCGCCTA CTGCCCCCTG 
GTGCTCAAAT TTCAGTTCTG CAGCCGAGCC TACTTCCGCC AGATGTGCTG CAAAACCTGC 
CATGGCCACT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ADAMTS10 ( XM_017027338.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_016882827.1 Homo sapiens ADAM metallopeptidase with thrombospondin type 1 motif 10 (ADAMTS10), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu20510
Clone ID Related Accession (Same CDS sequence)	NM_030957.4 , XM_017027338.1 , XM_017027338.2 , NM_030957.3
Accession Version	XM_017027338.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3312bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	A disintegrin and metalloproteinase with thrombospondin motifs 10 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000019.10) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_017027338.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCTCCCG CCTGCCAGAT CCTCCGCTGG GCCCTCGCCC TGGGGCTGGG CCTCATGTTC 
GAGGTCACGC ACGCCTTCCG GTCTCAAGAT GAGTTCCTGT CCAGTCTGGA GAGCTATGAG 
ATCGCCTTCC CCACCCGCGT GGACCACAAC GGGGCACTGC TGGCCTTCTC GCCACCTCCT 
CCCCGGAGGC AGCGCCGCGG CACGGGGGCC ACAGCCGAGT CCCGCCTCTT CTACAAAGTG 
GCCTCGCCCA GCACCCACTT CCTGCTGAAC CTGACCCGCA GCTCCCGTCT ACTGGCAGGG 
CACGTCTCCG TGGAGTACTG GACACGGGAG GGCCTGGCCT GGCAGAGGGC GGCCCGGCCC 
CACTGCCTCT ACGCTGGTCA CCTGCAGGGC CAGGCCAGCA GCTCCCATGT GGCCATCAGC 
ACCTGTGGAG GCCTGCACGG CCTGATCGTG GCAGACGAGG AAGAGTACCT GATTGAGCCC 
CTGCACGGTG GGCCCAAGGG TTCTCGGAGC CCGGAGGAAA GTGGACCACA TGTGGTGTAC 
AAGCGTTCCT CTCTGCGTCA CCCCCACCTG GACACAGCCT GTGGAGTGAG AGATGAGAAA 
CCGTGGAAAG GGCGGCCATG GTGGCTGCGG ACCTTGAAGC CACCGCCTGC CAGGCCCCTG 
GGGAATGAAA CAGAGCGTGG CCAGCCAGGC CTGAAGCGAT CGGTCAGCCG AGAGCGCTAC 
GTGGAGACCC TGGTGGTGGC TGACAAGATG ATGGTGGCCT ATCACGGGCG CCGGGATGTG 
GAGCAGTATG TCCTGGCCAT CATGAACATT GTTGCCAAAC TTTTCCAGGA CTCGAGTCTG 
GGAAGCACCG TTAACATCCT CGTAACTCGC CTCATCCTGC TCACGGAGGA CCAGCCCACT 
CTGGAGATCA CCCACCATGC CGGGAAGTCC CTGGACAGCT TCTGTAAGTG GCAGAAATCC 
ATCGTGAACC ACAGCGGCCA TGGCAATGCC ATTCCAGAGA ACGGTGTGGC TAACCATGAC 
ACAGCAGTGC TCATCACACG CTATGACATC TGCATCTACA AGAACAAACC CTGCGGCACA 
CTAGGCCTGG CCCCGGTGGG CGGAATGTGT GAGCGCGAGA GAAGCTGCAG CGTCAATGAG 
GACATTGGCC TGGCCACAGC GTTCACCATT GCCCACGAGA TCGGGCACAC ATTCGGCATG 
AACCATGACG GCGTGGGAAA CAGCTGTGGG GCCCGTGGTC AGGACCCAGC CAAGCTCATG 
GCTGCCCACA TTACCATGAA GACCAACCCA TTCGTGTGGT CATCCTGCAG CCGTGACTAC 
ATCACCAGCT TTCTAGACTC GGGCCTGGGG CTCTGCCTGA ACAACCGGCC CCCCAGACAG 
GACTTTGTGT ACCCGACAGT GGCACCGGGC CAAGCCTACG ATGCAGATGA GCAATGCCGC 
TTTCAGCATG GAGTCAAATC GCGTCAGTGT AAATACGGGG AGGTCTGCAG CGAGCTGTGG 
TGTCTGAGCA AGAGCAACCG GTGCATCACC AACAGCATCC CGGCCGCCGA GGGCACGCTG 
TGCCAGACGC ACACCATCGA CAAGGGGTGG TGCTACAAAC GGGTCTGTGT CCCCTTTGGG 
TCGCGCCCAG AGGGTGTGGA CGGAGCCTGG GGGCCGTGGA CTCCATGGGG CGACTGCAGC 
CGGACCTGTG GCGGCGGCGT GTCCTCTTCT AGCCGTCACT GCGACAGCCC CAGGCCAACC 
ATCGGGGGCA AGTACTGTCT GGGTGAGAGA AGGCGGCACC GCTCCTGCAA CACGGATGAC 
TGTCCCCCTG GCTCCCAGGA CTTCAGAGAA GTGCAGTGTT CTGAATTTGA CAGCATCCCT 
TTCCGTGGGA AATTCTACAA GTGGAAAACG TACCGGGGAG GGGGCGTGAA GGCCTGCTCG 
CTCACGTGCC TAGCGGAAGG CTTCAACTTC TACACGGAGA GGGCGGCAGC CGTGGTGGAC 
GGGACACCCT GCCGTCCAGA CACGGTGGAC ATTTGCGTCA GTGGCGAATG CAAGCACGTG 
GGCTGCGACC GAGTCCTGGG CTCCGACCTG CGGGAGGACA AGTGCCGAGT GTGTGGCGGT 
GACGGCAGTG CCTGCGAGAC CATCGAGGGC GTCTTCAGCC CAGCCTCACC TGGGGCCGGG 
TACGAGGATG TCGTCTGGAT TCCCAAAGGC TCCGTCCACA TCTTCATCCA GGATCTGAAC 
CTCTCTCTCA GTCACTTGGC CCTGAAGGGA GACCAGGAGT CCCTGCTGCT GGAGGGGCTG 
CCTGGGACCC CCCAGCCCCA CCGTCTGCCT CTAGCTGGGA CCACCTTTCA ACTGCGACAG 
GGGCCAGACC AGGTCCAGAG CCTCGAAGCC CTGGGACCGA TTAATGCATC TCTCATCGTC 
ATGGTGCTGG CCCGGACCGA GCTGCCTGCC CTCCGCTACC GCTTCAATGC CCCCATCGCC 
CGTGACTCGC TGCCCCCCTA CTCCTGGCAC TATGCGCCCT GGACCAAGTG CTCGGCCCAG 
TGTGCAGGCG GTAGCCAGGT GCAGGCGGTG GAGTGCCGCA ACCAGCTGGA CAGCTCCGCG 
GTCGCCCCCC ACTACTGCAG TGCCCACAGC AAGCTGCCCA AAAGGCAGCG CGCCTGCAAC 
ACGGAGCCTT GCCCTCCAGA CTGGGTTGTA GGGAACTGGT CGCTCTGCAG CCGCAGCTGC 
GATGCAGGCG TGCGCAGCCG CTCGGTCGTG TGCCAGCGCC GCGTCTCTGC CGCGGAGGAG 
AAGGCGCTGG ACGACAGCGC ATGCCCGCAG CCGCGCCCAC CTGTACTGGA GGCCTGCCAC 
GGCCCCACTT GCCCTCCGGA GTGGGCGGCC CTCGACTGGT CTGAGTGCAC CCCCAGCTGC 
GGGCCGGGCC TCCGCCACCG CGTGGTCCTT TGCAAGAGCG CAGACCACCG CGCCACGCTG 
CCCCCGGCGC ACTGCTCACC CGCCGCCAAG CCACCGGCCA CCATGCGCTG CAACTTGCGC 
CGCTGCCCCC CGGCCCGCTG GGTGGCTGGC GAGTGGGGTG AGTGCTCTGC ACAGTGCGGC 
GTCGGGCAGC GGCAGCGCTC GGTGCGCTGC ACCAGCCACA CGGGCCAGGC GTCGCACGAG 
TGCACGGAGG CCCTGCGGCC GCCCACCACG CAGCAGTGTG AGGCCAAGTG CGACAGCCCA 
ACCCCCGGGG ACGGCCCTGA AGAGTGCAAG GATGTGAACA AGGTCGCCTA CTGCCCCCTG 
GTGCTCAAAT TTCAGTTCTG CAGCCGAGCC TACTTCCGCC AGATGTGCTG CAAAACCTGC 
CATGGCCACT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016882827.1
CDS	163..3474
Translation	MAPACQILRWALALGLGLMFEVTHAFRSQDEFLSSLESYEIAFPTRVDHNGALLAFSPPPPRRQRRGTGATAESRLFYKVASPSTHFLLNLTRSSRLLAGHVSVEYWTREGLAWQRAARPHCLYAGHLQGQASSSHVAISTCGGLHGLIVADEEEYLIEPLHGGPKGSRSPEESGPHVVYKRSSLRHPHLDTACGVRDEKPWKGRPWWLRTLKPPPARPLGNETERGQPGLKRSVSRERYVETLVVADKMMVAYHGRRDVEQYVLAIMNIVAKLFQDSSLGSTVNILVTRLILLTEDQPTLEITHHAGKSLDSFCKWQKSIVNHSGHGNAIPENGVANHDTAVLITRYDICIYKNKPCGTLGLAPVGGMCERERSCSVNEDIGLATAFTIAHEIGHTFGMNHDGVGNSCGARGQDPAKLMAAHITMKTNPFVWSSCSRDYITSFLDSGLGLCLNNRPPRQDFVYPTVAPGQAYDADEQCRFQHGVKSRQCKYGEVCSELWCLSKSNRCITNSIPAAEGTLCQTHTIDKGWCYKRVCVPFGSRPEGVDGAWGPWTPWGDCSRTCGGGVSSSSRHCDSPRPTIGGKYCLGERRRHRSCNTDDCPPGSQDFREVQCSEFDSIPFRGKFYKWKTYRGGGVKACSLTCLAEGFNFYTERAAAVVDGTPCRPDTVDICVSGECKHVGCDRVLGSDLREDKCRVCGGDGSACETIEGVFSPASPGAGYEDVVWIPKGSVHIFIQDLNLSLSHLALKGDQESLLLEGLPGTPQPHRLPLAGTTFQLRQGPDQVQSLEALGPINASLIVMVLARTELPALRYRFNAPIARDSLPPYSWHYAPWTKCSAQCAGGSQVQAVECRNQLDSSAVAPHYCSAHSKLPKRQRACNTEPCPPDWVVGNWSLCSRSCDAGVRSRSVVCQRRVSAAEEKALDDSACPQPRPPVLEACHGPTCPPEWAALDWSECTPSCGPGLRHRVVLCKSADHRATLPPAHCSPAAKPPATMRCNLRRCPPARWVAGEWGECSAQCGVGQRQRSVRCTSHTGQASHECTEALRPPTTQQCEAKCDSPTPGDGPEECKDVNKVAYCPLVLKFQFCSRAYFRQMCCKTCHGH

Target ORF information:

RefSeq Version	XM_017027338.2
Organism	Homo sapiens(human)
Definition	Homo sapiens ADAM metallopeptidase with thrombospondin type 1 motif 10 (ADAMTS10), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017027338.2

ORF Insert Sequence:

ATGGCTCCCG CCTGCCAGAT CCTCCGCTGG GCCCTCGCCC TGGGGCTGGG CCTCATGTTC 
GAGGTCACGC ACGCCTTCCG GTCTCAAGAT GAGTTCCTGT CCAGTCTGGA GAGCTATGAG 
ATCGCCTTCC CCACCCGCGT GGACCACAAC GGGGCACTGC TGGCCTTCTC GCCACCTCCT 
CCCCGGAGGC AGCGCCGCGG CACGGGGGCC ACAGCCGAGT CCCGCCTCTT CTACAAAGTG 
GCCTCGCCCA GCACCCACTT CCTGCTGAAC CTGACCCGCA GCTCCCGTCT ACTGGCAGGG 
CACGTCTCCG TGGAGTACTG GACACGGGAG GGCCTGGCCT GGCAGAGGGC GGCCCGGCCC 
CACTGCCTCT ACGCTGGTCA CCTGCAGGGC CAGGCCAGCA GCTCCCATGT GGCCATCAGC 
ACCTGTGGAG GCCTGCACGG CCTGATCGTG GCAGACGAGG AAGAGTACCT GATTGAGCCC 
CTGCACGGTG GGCCCAAGGG TTCTCGGAGC CCGGAGGAAA GTGGACCACA TGTGGTGTAC 
AAGCGTTCCT CTCTGCGTCA CCCCCACCTG GACACAGCCT GTGGAGTGAG AGATGAGAAA 
CCGTGGAAAG GGCGGCCATG GTGGCTGCGG ACCTTGAAGC CACCGCCTGC CAGGCCCCTG 
GGGAATGAAA CAGAGCGTGG CCAGCCAGGC CTGAAGCGAT CGGTCAGCCG AGAGCGCTAC 
GTGGAGACCC TGGTGGTGGC TGACAAGATG ATGGTGGCCT ATCACGGGCG CCGGGATGTG 
GAGCAGTATG TCCTGGCCAT CATGAACATT GTTGCCAAAC TTTTCCAGGA CTCGAGTCTG 
GGAAGCACCG TTAACATCCT CGTAACTCGC CTCATCCTGC TCACGGAGGA CCAGCCCACT 
CTGGAGATCA CCCACCATGC CGGGAAGTCC CTGGACAGCT TCTGTAAGTG GCAGAAATCC 
ATCGTGAACC ACAGCGGCCA TGGCAATGCC ATTCCAGAGA ACGGTGTGGC TAACCATGAC 
ACAGCAGTGC TCATCACACG CTATGACATC TGCATCTACA AGAACAAACC CTGCGGCACA 
CTAGGCCTGG CCCCGGTGGG CGGAATGTGT GAGCGCGAGA GAAGCTGCAG CGTCAATGAG 
GACATTGGCC TGGCCACAGC GTTCACCATT GCCCACGAGA TCGGGCACAC ATTCGGCATG 
AACCATGACG GCGTGGGAAA CAGCTGTGGG GCCCGTGGTC AGGACCCAGC CAAGCTCATG 
GCTGCCCACA TTACCATGAA GACCAACCCA TTCGTGTGGT CATCCTGCAG CCGTGACTAC 
ATCACCAGCT TTCTAGACTC GGGCCTGGGG CTCTGCCTGA ACAACCGGCC CCCCAGACAG 
GACTTTGTGT ACCCGACAGT GGCACCGGGC CAAGCCTACG ATGCAGATGA GCAATGCCGC 
TTTCAGCATG GAGTCAAATC GCGTCAGTGT AAATACGGGG AGGTCTGCAG CGAGCTGTGG 
TGTCTGAGCA AGAGCAACCG GTGCATCACC AACAGCATCC CGGCCGCCGA GGGCACGCTG 
TGCCAGACGC ACACCATCGA CAAGGGGTGG TGCTACAAAC GGGTCTGTGT CCCCTTTGGG 
TCGCGCCCAG AGGGTGTGGA CGGAGCCTGG GGGCCGTGGA CTCCATGGGG CGACTGCAGC 
CGGACCTGTG GCGGCGGCGT GTCCTCTTCT AGCCGTCACT GCGACAGCCC CAGGCCAACC 
ATCGGGGGCA AGTACTGTCT GGGTGAGAGA AGGCGGCACC GCTCCTGCAA CACGGATGAC 
TGTCCCCCTG GCTCCCAGGA CTTCAGAGAA GTGCAGTGTT CTGAATTTGA CAGCATCCCT 
TTCCGTGGGA AATTCTACAA GTGGAAAACG TACCGGGGAG GGGGCGTGAA GGCCTGCTCG 
CTCACGTGCC TAGCGGAAGG CTTCAACTTC TACACGGAGA GGGCGGCAGC CGTGGTGGAC 
GGGACACCCT GCCGTCCAGA CACGGTGGAC ATTTGCGTCA GTGGCGAATG CAAGCACGTG 
GGCTGCGACC GAGTCCTGGG CTCCGACCTG CGGGAGGACA AGTGCCGAGT GTGTGGCGGT 
GACGGCAGTG CCTGCGAGAC CATCGAGGGC GTCTTCAGCC CAGCCTCACC TGGGGCCGGG 
TACGAGGATG TCGTCTGGAT TCCCAAAGGC TCCGTCCACA TCTTCATCCA GGATCTGAAC 
CTCTCTCTCA GTCACTTGGC CCTGAAGGGA GACCAGGAGT CCCTGCTGCT GGAGGGGCTG 
CCTGGGACCC CCCAGCCCCA CCGTCTGCCT CTAGCTGGGA CCACCTTTCA ACTGCGACAG 
GGGCCAGACC AGGTCCAGAG CCTCGAAGCC CTGGGACCGA TTAATGCATC TCTCATCGTC 
ATGGTGCTGG CCCGGACCGA GCTGCCTGCC CTCCGCTACC GCTTCAATGC CCCCATCGCC 
CGTGACTCGC TGCCCCCCTA CTCCTGGCAC TATGCGCCCT GGACCAAGTG CTCGGCCCAG 
TGTGCAGGCG GTAGCCAGGT GCAGGCGGTG GAGTGCCGCA ACCAGCTGGA CAGCTCCGCG 
GTCGCCCCCC ACTACTGCAG TGCCCACAGC AAGCTGCCCA AAAGGCAGCG CGCCTGCAAC 
ACGGAGCCTT GCCCTCCAGA CTGGGTTGTA GGGAACTGGT CGCTCTGCAG CCGCAGCTGC 
GATGCAGGCG TGCGCAGCCG CTCGGTCGTG TGCCAGCGCC GCGTCTCTGC CGCGGAGGAG 
AAGGCGCTGG ACGACAGCGC ATGCCCGCAG CCGCGCCCAC CTGTACTGGA GGCCTGCCAC 
GGCCCCACTT GCCCTCCGGA GTGGGCGGCC CTCGACTGGT CTGAGTGCAC CCCCAGCTGC 
GGGCCGGGCC TCCGCCACCG CGTGGTCCTT TGCAAGAGCG CAGACCACCG CGCCACGCTG 
CCCCCGGCGC ACTGCTCACC CGCCGCCAAG CCACCGGCCA CCATGCGCTG CAACTTGCGC 
CGCTGCCCCC CGGCCCGCTG GGTGGCTGGC GAGTGGGGTG AGTGCTCTGC ACAGTGCGGC 
GTCGGGCAGC GGCAGCGCTC GGTGCGCTGC ACCAGCCACA CGGGCCAGGC GTCGCACGAG 
TGCACGGAGG CCCTGCGGCC GCCCACCACG CAGCAGTGTG AGGCCAAGTG CGACAGCCCA 
ACCCCCGGGG ACGGCCCTGA AGAGTGCAAG GATGTGAACA AGGTCGCCTA CTGCCCCCTG 
GTGCTCAAAT TTCAGTTCTG CAGCCGAGCC TACTTCCGCC AGATGTGCTG CAAAACCTGC 
CATGGCCACT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

ADAMTS-10 and -6 differentially regulate cell-cell junctions and focal adhesions.
Scientific reports635956(2016 Oct)
Cain SA,Mularczyk EJ,Singh M,Massam-Wu T,Kielty CM

Screening ADAMTS10 in dog populations supports Gly661Arg as the glaucoma-causing variant in beagles.
Investigative ophthalmology & visual science54(3)1881-6(2013 Mar)
Kuchtey J,Kunkel J,Esson D,Sapienza JS,Ward DA,Plummer CE,Gelatt KN,Kuchtey RW

SuperTAG methylation-specific digital karyotyping reveals uremia-induced epigenetic dysregulation of atherosclerosis-related genes.
Circulation. Cardiovascular genetics5(6)611-20(2012 Dec)
Zawada AM,Rogacev KS,Hummel B,Gr?n OS,Friedrich A,Rotter B,Winter P,Geisel J,Fliser D,Heine GH

ADAMTS10 protein interacts with fibrillin-1 and promotes its deposition in extracellular matrix of cultured fibroblasts.
The Journal of biological chemistry286(19)17156-67(2011 May)
Kutz WE,Wang LW,Bader HL,Majors AK,Iwata K,Traboulsi EI,Sakai LY,Keene DR,Apte SS

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ADAMTS10 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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