Gene Symbol | CDT1 |
Entrez Gene ID | 81620 |
Full Name | chromatin licensing and DNA replication factor 1 |
Synonyms | DUP,RIS2 |
General protein information |
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Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Summary | The protein encoded by this gene is involved in the formation of the pre-replication complex that is necessary for DNA replication. The encoded protein can bind geminin, which prevents replication and may function to prevent this protein from initiating replication at inappropriate origins. Phosphorylation of this protein by cyclin A-dependent kinases results in degradation of the protein. [provided by RefSeq, Mar 2011]. |
Disorder MIM: | |
Disorder Html: | Meier-Gorlin syndrome 4, 613804 (3) |