Gene Symbol | CAMK2B |
Entrez Gene ID | 816 |
Full Name | calcium/calmodulin dependent protein kinase II beta |
Synonyms | CAM2,CAMK2,CAMKB,MRD54 |
General protein information |
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Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Summary | The product of this gene belongs to the serine/threonine protein kinase family and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. In mammalian cells, the enzyme is composed of four different chains: alpha, beta, gamma, and delta. The product of this gene is a beta chain. It is possible that distinct isoforms of this chain have different cellular localizations and interact differently with calmodulin. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014]. |
Disorder MIM: | |
Disorder Html: | Mental retardation, autosomal dominant 54, 617799 (3) |