MOB2 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	MOB2
Entrez Gene ID	81532
Full Name	MOB kinase activator 2
Synonyms	HCCA2
General protein information	Preferred Names MOB kinase activator 2 Names MOB kinase activator 2 MOB2 Mps One Binder homolog Mps one binder kinase activator-like 2
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 11 Map Location: 11p15.5
Disorder MIM:	611969

mRNA and Protein(s)

mRNA	Protein	Name
NM_001172223.2	NP_001165694.1	MOB kinase activator 2 isoform 1
NM_053005.5	NP_443731.2	MOB kinase activator 2 isoform 2
NM_001172223.3	NP_001165694.1	MOB kinase activator 2 isoform 1

Pathways from BioSystems

Homologies

Mus musculus (house mouse)	Mob2	NP_082584.1
Homo sapiens (human)	MOB2	NP_001165694.1
Pan troglodytes (chimpanzee)	MOB2	XP_001152532.2
Canis lupus familiaris (dog)	MOB2	XP_854258.2
Rattus norvegicus (Norway rat)	Mob2	NP_001102629.1
Danio rerio (zebrafish)	mob2b	NP_001038782.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP010841	XP_309864.4
Xenopus tropicalis (tropical clawed frog)	mob2.1	NP_989013.1
Gallus gallus (chicken)	MOB2	XP_421030.1
Danio rerio (zebrafish)	mob2a	NP_001002364.1

Gene Ontology
Bibliography

Related articles in PubMed

Architecture of the human interactome defines protein communities and disease networks.
Huttlin EL, Bruckner RJ, Paulo JA, Cannon JR, Ting L, Baltier K, Colby G, Gebreab F, Gygi MP, Parzen H, Szpyt J, Tam S, Zarraga G, Pontano-Vaites L, Swarup S, White AE, Schweppe DK, Rad R, Erickson BK, Obar RA, Guruharsha KG, Li K, Artavanis-Tsakonas S, Gygi SP, Harper JW
Nature545(7655)505-509(2017 05)

Modulation of tumor cell migration, invasion and cell-matrix adhesion by human monopolar spindle-one-binder 2.
Wu W, Zhang X, Qin H, Peng W, Xue Q, Lv H, Zhang H, Qiu Y, Cheng H, Zhang Y, Yu Z, Shen W
Oncology reports33(5)2495-503(2015 May)

Integrative analysis of kinase networks in TRAIL-induced apoptosis provides a source of potential targets for combination therapy.
So J, Pasculescu A, Dai AY, Williton K, James A, Nguyen V, Creixell P, Schoof EM, Sinclair J, Barrios-Rodiles M, Gu J, Krizus A, Williams R, Olhovsky M, Dennis JW, Wrana JL, Linding R, Jorgensen C, Pawson T, Colwill K
Science signaling8(371)rs3(2015 Apr)

Regulation of DNA damage responses and cell cycle progression by hMOB2.
Gomez V, Gundogdu R, Gomez M, Hoa L, Panchal N, O'Driscoll M, Hergovich A
Cellular signalling27(2)326-39(2015 Feb)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The altered cell-matrix adhesion and cell motility induced by hMOB2 expression was caused by the assembly of focal adhesions.
Title: Modulation of tumor cell migration, invasion and cell-matrix adhesion by human monopolar spindle-one-binder 2.

hMOB2 interacts with RAD50, facilitating the recruitment of the MRE11-RAD50-NBS1 (MRN) DNA damage sensor complex and activated ATM to DNA damaged chromatin.
Title: Regulation of DNA damage responses and cell cycle progression by hMOB2.

MOB2 overexpression induces apoptosis and inhibits the growth of human hepatic cancer cells
Title: Growth-inhibitory effects of MOB2 on human hepatic carcinoma cell line SMMC-7721.

Observational study of gene-disease association, gene-gene interaction, and gene-environment interaction. (HuGE Navigator)
Title: Genetic risk reclassification for type 2 diabetes by age below or above 50 years using 40 type 2 diabetes risk single nucleotide polymorphisms.

Data indicate that human MOB2 is a negative regulator of human NDR kinases in biochemical and biological settings.
Title: Differential NDR/LATS interactions with the human MOB family reveal a negative role for human MOB2 in the regulation of human NDR kinases.

The following MOB2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the MOB2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu16037	NM_053005.5 Latest version!	Homo sapiens MOB kinase activator 2 (MOB2), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$139.30 $199.00
OHu16039	NM_001172223.3 Latest version!	Homo sapiens MOB kinase activator 2 (MOB2), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$216.30 $309.00
View Old Accession Versions >>
OHu16039	NM_001172223.2	Homo sapiens MOB kinase activator 2 (MOB2), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$216.30 $309.00
Hide Old Accession Versions >>

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

MOB2 ( NM_053005.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_443731.2 Homo sapiens MOB kinase activator 2 (MOB2), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu16037
Clone ID Related Accession (Same CDS sequence)	NM_053005.5
Accession Version	NM_053005.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 714bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-10
Organism	Homo sapiens(human)
Product	MOB kinase activator 2 isoform 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from HY032250.1, DC413532.1, BC067785.1, BC047291.1, AW874617.1 and BP388313.1. On Apr 15, 2014 this sequence version replaced NM_053005.4. Transcript Variant: This variant (2) represents use of an alternate promoter and differs in the 5' UTR and 5' coding region, compared to variant 1. The resulting isoform (2) has a shorter and distinct N-terminus, compared to isoform 1. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMEA2467148 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGACTGGC TCATGGGGAA GTCCAAAGCC AAGCCTAATG GCAAGAAGCC CGCTGCGGAG 
GAGAGGAAGG CCTACCTGGA GCCTGAGCAC ACCAAGGCCA GGATCACCGA CTTCCAGTTC 
AAGGAGCTGG TGGTGCTGCC CCGCGAGATT GACCTTAACG AGTGGCTGGC CAGCAACACC 
ACGACGTTTT TCCACCACAT CAACCTGCAG TATAGCACCA TCTCCGAGTT CTGCACAGGA 
GAGACGTGTC AGACGATGGC CGTGTGCAAC ACACAGTACT ACTGGTATGA CGAGCGGGGG 
AAGAAGGTCA AGTGCACGGC CCCACAGTAC GTTGACTTCG TCATGAGCTC CGTGCAGAAG 
CTGGTGACGG ATGAGGACGT GTTCCCCACA AAATACGGCA GAGAATTCCC CAGCTCCTTT 
GAGTCCCTGG TGAGGAAGAT CTGCAGACAC CTGTTCCACG TGCTGGCACA CATCTACTGG 
GCCCACTTCA AGGAGACGCT GGCCCTGGAG CTGCACGGAC ACTTGAACAC GCTCTACGTC 
CACTTCATCC TCTTTGCTCG GGAGTTCAAC CTGCTGGACC CCAAAGAGAC CGCCATCATG 
GACGACCTCA CCGAGGTGCT ATGCAGCGGG GCCGGCGGGG TCCACAGTGG GGGCAGTGGG 
GATGGGGCCG GCAGCGGGGG CCCGGGAGCA CAGAACCACG TGAAGGAGAG ATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_443731.2
CDS	104..817
Translation	MDWLMGKSKAKPNGKKPAAEERKAYLEPEHTKARITDFQFKELVVLPREIDLNEWLASNTTTFFHHINLQYSTISEFCTGETCQTMAVCNTQYYWYDERGKKVKCTAPQYVDFVMSSVQKLVTDEDVFPTKYGREFPSSFESLVRKICRHLFHVLAHIYWAHFKETLALELHGHLNTLYVHFILFAREFNLLDPKETAIMDDLTEVLCSGAGGVHSGGSGDGAGSGGPGAQNHVKER

Target ORF information:

RefSeq Version	NM_053005.5
Organism	Homo sapiens(human)
Definition	Homo sapiens MOB kinase activator 2 (MOB2), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_053005.5

ORF Insert Sequence:

ATGGACTGGC TCATGGGGAA GTCCAAAGCC AAGCCTAATG GCAAGAAGCC CGCTGCGGAG 
GAGAGGAAGG CCTACCTGGA GCCTGAGCAC ACCAAGGCCA GGATCACCGA CTTCCAGTTC 
AAGGAGCTGG TGGTGCTGCC CCGCGAGATT GACCTTAACG AGTGGCTGGC CAGCAACACC 
ACGACGTTTT TCCACCACAT CAACCTGCAG TATAGCACCA TCTCCGAGTT CTGCACAGGA 
GAGACGTGTC AGACGATGGC CGTGTGCAAC ACACAGTACT ACTGGTATGA CGAGCGGGGG 
AAGAAGGTCA AGTGCACGGC CCCACAGTAC GTTGACTTCG TCATGAGCTC CGTGCAGAAG 
CTGGTGACGG ATGAGGACGT GTTCCCCACA AAATACGGCA GAGAATTCCC CAGCTCCTTT 
GAGTCCCTGG TGAGGAAGAT CTGCAGACAC CTGTTCCACG TGCTGGCACA CATCTACTGG 
GCCCACTTCA AGGAGACGCT GGCCCTGGAG CTGCACGGAC ACTTGAACAC GCTCTACGTC 
CACTTCATCC TCTTTGCTCG GGAGTTCAAC CTGCTGGACC CCAAAGAGAC CGCCATCATG 
GACGACCTCA CCGAGGTGCT ATGCAGCGGG GCCGGCGGGG TCCACAGTGG GGGCAGTGGG 
GATGGGGCCG GCAGCGGGGG CCCGGGAGCA CAGAACCACG TGAAGGAGAG ATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MOB2 ( NM_001172223.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001165694.1 Homo sapiens MOB kinase activator 2 (MOB2), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu16039
Clone ID Related Accession (Same CDS sequence)	NM_001172223.2 , NM_001172223.3
Accession Version	NM_001172223.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 807bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-02
Organism	Homo sapiens(human)
Product	MOB kinase activator 2 isoform 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC091196.6, DC413532.1, AK296658.1, BC047291.1, AW874617.1 and BP388313.1. On Apr 15, 2014 this sequence version replaced NM_001172223.1. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). ##Evidence-Data-START## Transcript exon combination :: ERR279857.515.1, ERR279848.7072.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2467148 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCTGGGAG ACCACTGCAG TCTCCCTGAA GACCAAGCCC GGCCCGGCCA GTCCCTGCAA 
AGTGGACTCT GCTGCAAAAT GGTGCTTCAG GCTGTCAGCA AAGTGCTCAG GAAGTCCAAA 
GCCAAGCCTA ATGGCAAGAA GCCCGCTGCG GAGGAGAGGA AGGCCTACCT GGAGCCTGAG 
CACACCAAGG CCAGGATCAC CGACTTCCAG TTCAAGGAGC TGGTGGTGCT GCCCCGCGAG 
ATTGACCTTA ACGAGTGGCT GGCCAGCAAC ACCACGACGT TTTTCCACCA CATCAACCTG 
CAGTATAGCA CCATCTCCGA GTTCTGCACA GGAGAGACGT GTCAGACGAT GGCCGTGTGC 
AACACACAGT ACTACTGGTA TGACGAGCGG GGGAAGAAGG TCAAGTGCAC GGCCCCACAG 
TACGTTGACT TCGTCATGAG CTCCGTGCAG AAGCTGGTGA CGGATGAGGA CGTGTTCCCC 
ACAAAATACG GCAGAGAATT CCCCAGCTCC TTTGAGTCCC TGGTGAGGAA GATCTGCAGA 
CACCTGTTCC ACGTGCTGGC ACACATCTAC TGGGCCCACT TCAAGGAGAC GCTGGCCCTG 
GAGCTGCACG GACACTTGAA CACGCTCTAC GTCCACTTCA TCCTCTTTGC TCGGGAGTTC 
AACCTGCTGG ACCCCAAAGA GACCGCCATC ATGGACGACC TCACCGAGGT GCTATGCAGC 
GGGGCCGGCG GGGTCCACAG TGGGGGCAGT GGGGATGGGG CCGGCAGCGG GGGCCCGGGA 
GCACAGAACC ACGTGAAGGA GAGATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001165694.1
CDS	224..1030
Translation	MLGDHCSLPEDQARPGQSLQSGLCCKMVLQAVSKVLRKSKAKPNGKKPAAEERKAYLEPEHTKARITDFQFKELVVLPREIDLNEWLASNTTTFFHHINLQYSTISEFCTGETCQTMAVCNTQYYWYDERGKKVKCTAPQYVDFVMSSVQKLVTDEDVFPTKYGREFPSSFESLVRKICRHLFHVLAHIYWAHFKETLALELHGHLNTLYVHFILFAREFNLLDPKETAIMDDLTEVLCSGAGGVHSGGSGDGAGSGGPGAQNHVKER

Target ORF information:

RefSeq Version	NM_001172223.2
Organism	Homo sapiens(human)
Definition	Homo sapiens MOB kinase activator 2 (MOB2), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001172223.2

ORF Insert Sequence:

ATGCTGGGAG ACCACTGCAG TCTCCCTGAA GACCAAGCCC GGCCCGGCCA GTCCCTGCAA 
AGTGGACTCT GCTGCAAAAT GGTGCTTCAG GCTGTCAGCA AAGTGCTCAG GAAGTCCAAA 
GCCAAGCCTA ATGGCAAGAA GCCCGCTGCG GAGGAGAGGA AGGCCTACCT GGAGCCTGAG 
CACACCAAGG CCAGGATCAC CGACTTCCAG TTCAAGGAGC TGGTGGTGCT GCCCCGCGAG 
ATTGACCTTA ACGAGTGGCT GGCCAGCAAC ACCACGACGT TTTTCCACCA CATCAACCTG 
CAGTATAGCA CCATCTCCGA GTTCTGCACA GGAGAGACGT GTCAGACGAT GGCCGTGTGC 
AACACACAGT ACTACTGGTA TGACGAGCGG GGGAAGAAGG TCAAGTGCAC GGCCCCACAG 
TACGTTGACT TCGTCATGAG CTCCGTGCAG AAGCTGGTGA CGGATGAGGA CGTGTTCCCC 
ACAAAATACG GCAGAGAATT CCCCAGCTCC TTTGAGTCCC TGGTGAGGAA GATCTGCAGA 
CACCTGTTCC ACGTGCTGGC ACACATCTAC TGGGCCCACT TCAAGGAGAC GCTGGCCCTG 
GAGCTGCACG GACACTTGAA CACGCTCTAC GTCCACTTCA TCCTCTTTGC TCGGGAGTTC 
AACCTGCTGG ACCCCAAAGA GACCGCCATC ATGGACGACC TCACCGAGGT GCTATGCAGC 
GGGGCCGGCG GGGTCCACAG TGGGGGCAGT GGGGATGGGG CCGGCAGCGG GGGCCCGGGA 
GCACAGAACC ACGTGAAGGA GAGATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MOB2 ( NM_001172223.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_001165694.1 Homo sapiens MOB kinase activator 2 (MOB2), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu16039
Clone ID Related Accession (Same CDS sequence)	NM_001172223.2 , NM_001172223.3
Accession Version	NM_001172223.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 807bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-09
Organism	Homo sapiens(human)
Product	MOB kinase activator 2 isoform 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC091196.6, DC413532.1, AK296658.1, BC047291.1 and AW874617.1. On Nov 23, 2018 this sequence version replaced NM_001172223.2. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). ##Evidence-Data-START## Transcript exon combination :: SRR3476690.852508.1, ERR279857.515.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2467148 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000329957.7/ ENSP00000328694.6 RefSeq Select criteria :: based on conservation, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGCTGGGAG ACCACTGCAG TCTCCCTGAA GACCAAGCCC GGCCCGGCCA GTCCCTGCAA 
AGTGGACTCT GCTGCAAAAT GGTGCTTCAG GCTGTCAGCA AAGTGCTCAG GAAGTCCAAA 
GCCAAGCCTA ATGGCAAGAA GCCCGCTGCG GAGGAGAGGA AGGCCTACCT GGAGCCTGAG 
CACACCAAGG CCAGGATCAC CGACTTCCAG TTCAAGGAGC TGGTGGTGCT GCCCCGCGAG 
ATTGACCTTA ACGAGTGGCT GGCCAGCAAC ACCACGACGT TTTTCCACCA CATCAACCTG 
CAGTATAGCA CCATCTCCGA GTTCTGCACA GGAGAGACGT GTCAGACGAT GGCCGTGTGC 
AACACACAGT ACTACTGGTA TGACGAGCGG GGGAAGAAGG TCAAGTGCAC GGCCCCACAG 
TACGTTGACT TCGTCATGAG CTCCGTGCAG AAGCTGGTGA CGGATGAGGA CGTGTTCCCC 
ACAAAATACG GCAGAGAATT CCCCAGCTCC TTTGAGTCCC TGGTGAGGAA GATCTGCAGA 
CACCTGTTCC ACGTGCTGGC ACACATCTAC TGGGCCCACT TCAAGGAGAC GCTGGCCCTG 
GAGCTGCACG GACACTTGAA CACGCTCTAC GTCCACTTCA TCCTCTTTGC TCGGGAGTTC 
AACCTGCTGG ACCCCAAAGA GACCGCCATC ATGGACGACC TCACCGAGGT GCTATGCAGC 
GGGGCCGGCG GGGTCCACAG TGGGGGCAGT GGGGATGGGG CCGGCAGCGG GGGCCCGGGA 
GCACAGAACC ACGTGAAGGA GAGATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001165694.1
CDS	224..1030
Translation	MLGDHCSLPEDQARPGQSLQSGLCCKMVLQAVSKVLRKSKAKPNGKKPAAEERKAYLEPEHTKARITDFQFKELVVLPREIDLNEWLASNTTTFFHHINLQYSTISEFCTGETCQTMAVCNTQYYWYDERGKKVKCTAPQYVDFVMSSVQKLVTDEDVFPTKYGREFPSSFESLVRKICRHLFHVLAHIYWAHFKETLALELHGHLNTLYVHFILFAREFNLLDPKETAIMDDLTEVLCSGAGGVHSGGSGDGAGSGGPGAQNHVKER

Target ORF information:

RefSeq Version	NM_001172223.3
Organism	Homo sapiens(human)
Definition	Homo sapiens MOB kinase activator 2 (MOB2), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001172223.3

ORF Insert Sequence:

ATGCTGGGAG ACCACTGCAG TCTCCCTGAA GACCAAGCCC GGCCCGGCCA GTCCCTGCAA 
AGTGGACTCT GCTGCAAAAT GGTGCTTCAG GCTGTCAGCA AAGTGCTCAG GAAGTCCAAA 
GCCAAGCCTA ATGGCAAGAA GCCCGCTGCG GAGGAGAGGA AGGCCTACCT GGAGCCTGAG 
CACACCAAGG CCAGGATCAC CGACTTCCAG TTCAAGGAGC TGGTGGTGCT GCCCCGCGAG 
ATTGACCTTA ACGAGTGGCT GGCCAGCAAC ACCACGACGT TTTTCCACCA CATCAACCTG 
CAGTATAGCA CCATCTCCGA GTTCTGCACA GGAGAGACGT GTCAGACGAT GGCCGTGTGC 
AACACACAGT ACTACTGGTA TGACGAGCGG GGGAAGAAGG TCAAGTGCAC GGCCCCACAG 
TACGTTGACT TCGTCATGAG CTCCGTGCAG AAGCTGGTGA CGGATGAGGA CGTGTTCCCC 
ACAAAATACG GCAGAGAATT CCCCAGCTCC TTTGAGTCCC TGGTGAGGAA GATCTGCAGA 
CACCTGTTCC ACGTGCTGGC ACACATCTAC TGGGCCCACT TCAAGGAGAC GCTGGCCCTG 
GAGCTGCACG GACACTTGAA CACGCTCTAC GTCCACTTCA TCCTCTTTGC TCGGGAGTTC 
AACCTGCTGG ACCCCAAAGA GACCGCCATC ATGGACGACC TCACCGAGGT GCTATGCAGC 
GGGGCCGGCG GGGTCCACAG TGGGGGCAGT GGGGATGGGG CCGGCAGCGG GGGCCCGGGA 
GCACAGAACC ACGTGAAGGA GAGATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Architecture of the human interactome defines protein communities and disease networks.
Nature545(7655)505-509(2017 05)
Huttlin EL,Bruckner RJ,Paulo JA,Cannon JR,Ting L,Baltier K,Colby G,Gebreab F,Gygi MP,Parzen H,Szpyt J,Tam S,Zarraga G,Pontano-Vaites L,Swarup S,White AE,Schweppe DK,Rad R,Erickson BK,Obar RA,Guruharsha KG,Li K,Artavanis-Tsakonas S,Gygi SP,Harper JW

Modulation of tumor cell migration, invasion and cell-matrix adhesion by human monopolar spindle-one-binder 2.
Oncology reports33(5)2495-503(2015 May)
Wu W,Zhang X,Qin H,Peng W,Xue Q,Lv H,Zhang H,Qiu Y,Cheng H,Zhang Y,Yu Z,Shen W

Integrative analysis of kinase networks in TRAIL-induced apoptosis provides a source of potential targets for combination therapy.
Science signaling8(371)rs3(2015 Apr)
So J,Pasculescu A,Dai AY,Williton K,James A,Nguyen V,Creixell P,Schoof EM,Sinclair J,Barrios-Rodiles M,Gu J,Krizus A,Williams R,Olhovsky M,Dennis JW,Wrana JL,Linding R,Jorgensen C,Pawson T,Colwill K

Regulation of DNA damage responses and cell cycle progression by hMOB2.
Cellular signalling27(2)326-39(2015 Feb)
Gomez V,Gundogdu R,Gomez M,Hoa L,Panchal N,O'Driscoll M,Hergovich A

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MOB2 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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